Prescription Description
| Prescription ID | TCMFx6850 |
| Pinyin Name | Xin Nao Shu Tong Jiao Nang |
| Chinese Name | 心脑舒通胶囊 |
| English Name | Xin Nao Shu Tong Capsules |
| Function Description | 胸痹, 偏枯, 风痱 |
| Indications | Stroke |
| Disease ICD-11 Category |
8B20 [Stroke not known if ischaemic or haemorrhagic, 缺血或出血未知的卒中
]; |
| Human Tissues Associated with Indication | Heart, Lung |
| Reference | CFDA |
| Reference Book/link | http://samr.cfda.gov.cn/WS01/CL0001/ |
Prescription Components
| Component ID | Latin Name | Chinese Name | Component Quantity | Barcode |
|---|---|---|---|---|
| TCMH1024 | Tribulus terrestris | 蒺藜 | TCMH1024 | ITSAJ4258-14 |
Targeted Human Proteins by the Ingredients of Prescription
| Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
|---|---|---|---|---|
| TCMT208 | MAOA | Monoamine oxidase A | Oxidoreductase | P21397 |
| TCMT355 | CSNK1D | Casein kinase I delta | Kinase | P48730 |
| TCMT417 | DYRK2 | Dual-specificity tyrosine-phosphorylation regulated kinase 2 | Kinase | Q92630 |
| TCMT458 | HASPIN | Serine/threonine-protein kinase haspin | Kinase | Q8TF76 |
| TCMT473 | PIM3 | Serine/threonine-protein kinase PIM3 | Kinase | Q86V86 |
| TCMT751 | DYRK1A | Dual-specificity tyrosine-phosphorylation regulated kinase 1A | Kinase | Q13627 |
| TCMT763 | DYRK3 | Dual-specificity tyrosine-phosphorylation regulated kinase 3 | Kinase | O43781 |
| TCMT814 | CLK1 | Dual specificty protein kinase CLK1 | Kinase | P49759 |
| TCMT829 | NISCH | Nischarin | Unclassified | Q9Y2I1 |
| TCMT831 | DYRK4 | Dual specificity tyrosine-phosphorylation-regulated kinase 4 | Kinase | Q9NR20 |
| TCMT832 | DYRK1B | Dual specificity tyrosine-phosphorylation-regulated kinase 1B | Kinase | Q9Y463 |
Targeted Pathogenic Microbes by the Ingredients of Prescription
| Target ID | Target Name |
|---|---|
| TCMT1218 | Staphylococcus aureus |
| TCMT1223 | Staphylococcus epidermidis |
| TCMT1246 | Escherichia coli |
| TCMT1251 | Candida albicans |
| TCMT1408 | Colletotrichum gloeosporioides |
| TCMT1438 | Plasmodium falciparum |
| TCMT1442 | Leishmania donovani |
| TCMT1444 | Fusarium oxysporum |
| TCMT1454 | Bacillus subtilis |
| TCMT1463 | Mycobacterium tuberculosis |
Gene Ontology Associated to Targeted Human Proteins
| GO Term | GO Name | Enriched Genes | Log10 Adjusted P-value |
|---|
KEGG Pathways Associated to Targeted Human Proteins
| KEGG Pathway ID | Enriched Genes | Log10 Adjusted P-value |
|---|
Target Exprsssion in Healthy Human Tissues (protein & mRNA level)
Protein expression data was from the "Human Proteome Map" datasetmRNA expression data was from the "GTEx" dataset
Average Target Expression (Fold Change) in Multiple Disease Conditions
Fold Change with Corresponding Normal SamplesClick each cell within the heatmap to access gene expression of individual patient samples