Component: Atropa belladonna 颠茄流浸膏


Description of the Component

Component ID
 TCMH472
Latin Name
 Atropa belladonna
English Name
 belladonna
Chinese Pinyin Name
 Dian Qie Liu Jin Gao
中文名
 颠茄流浸膏
TCM Properties
TCM Meridians
Therapeutic Class English
Therapeutic Class Chinese
Functions
Toxicity
 NA
Geo-authentic habitats (道地产区)
 NA
Reference
 Chinese Pharmacopoeia (2015)
Barcode ID
 AY028147
Barcode Source
 GenBank

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name
TCMFx2964 An Mo Ru 按摩乳
TCMFx799 An Mo Ointment 按摩软膏
TCMFx3168 Bai Hua Huo Xue Die Da Ointment 百花活血跌打膏
TCMFx3656 Dong Chuang Wei Kui Ointment 冻疮未溃膏
TCMFx3479 Feng Shi Shang Tong Ointment 风湿伤痛膏
TCMF779 Fu Fang Ku Shen Chang Yan Kang Tablet 复方苦参肠炎康片
TCMFx3048 Fu Fang Tian Qi Wei Tong Capsules 复方田七胃痛胶囊
TCMFx3056 Fu Fang Tian Qi Wei Tong Tablets 复方田七胃痛片
TCMFx3450 Gu Jian Ling Ointment 骨健灵膏
TCMFx7128 Gu You Ling Ba Bu Ointment 骨友灵巴布膏
TCMFx3553 Gu You Ling Tie Ointment 骨友灵贴膏
TCMFx3678 Guan Jie Jie Tong Ointment 关节解痛膏
TCMF3703 Guan Jie Zhen Tong Ointment 关节镇痛膏
TCMFx3712 Guan Jie Zhi Tong Ointment 关节止痛膏
TCMFx491 Guan Jie Zhi Tong Ointment 关节止痛膏
TCMFx4445 Huo Xue Zhi Tong Ointment 活血止痛膏
TCMF5719 Shang Shi Bao Zhen Ointment 伤湿宝珍膏
TCMFx5728 Shang Shi Jie Tong Ointment 伤湿解痛膏
TCMFx5067 She Xiang Ba Shi Ointment 麝香拔湿膏
TCMFx1197 She Xiang Die Da Feng Shi Ointment 麝香跌打风湿膏
TCMFx5076 She Xiang Die Da Feng Shi Ointment 麝香跌打风湿膏
TCMFx5115 She Xiang Guan Jie Zhi Tong Ointment 麝香关节止痛膏
TCMFx5226 She Xiang Shang Shi Jie Tong Ointment 麝香伤湿解痛膏
TCMFx5283 She Xiang Zhi Chuang Shuan 麝香痔疮栓
TCMFx1196 She Xiang Zhi Chuang Suppository 麝香痔疮栓
TCMFx6906 She Xiang Zhui Feng Zhi Tong Ointment 麝香追风止痛膏
TCMFx5366 Shen Nong Zhen Tong Ointment 神农镇痛膏
TCMFx5342 Te Zhi Gou Pi Ointment 特制狗皮膏
TCMFx5682 Wei Le Capsules 胃乐胶囊
TCMFx5759 Wei Ning Powder 胃宁散
TCMFx5978 Xiang Gui Huo Xue Ointment 香桂活血膏
TCMFx6342 Yi Zhi Hao Shang Shi Qu Tong Ointment 一枝蒿伤湿祛痛膏
TCMF6484 Zhuang Gu She Xiang Zhi Tong Ointment 壮骨麝香止痛膏

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT1 EHMT2 Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 Transferase Q96KQ7
TCMT11 HIF1A Hypoxia-inducible factor 1 alpha Transcription factor Q16665
TCMT125 GBA Beta-glucocerebrosidase Hydrolase P04062
TCMT130 ALOX5 Arachidonate 5-lipoxygenase Oxidoreductase P09917
TCMT131 ACHE Acetylcholinesterase Hydrolase P22303
TCMT133 CA1 Carbonic anhydrase I Lyase P00915
TCMT134 CA2 Carbonic anhydrase II Lyase P00918
TCMT136 CA12 Carbonic anhydrase XII Lyase O43570
TCMT137 CA9 Carbonic anhydrase IX Lyase Q16790
TCMT138 CA7 Carbonic anhydrase VII Lyase P43166
TCMT162 UGT1A1 UDP-glucuronosyltransferase 1-1 Transferase P22309
TCMT17 POLB DNA polymerase beta Transferase P06746
TCMT18 GAA Lysosomal alpha-glucosidase Hydrolase P10253
TCMT193 RELA Nuclear factor NF-kappa-B p65 subunit Transcription factor Q04206
TCMT207 BACE1 Beta-secretase 1 Protease P56817
TCMT223 AKR1B1 Aldose reductase Oxidoreductase P15121
TCMT225 CA13 Carbonic anhydrase XIII Lyase Q8N1Q1
TCMT290 CHRM5 Muscarinic acetylcholine receptor M5 GPCR P08912
TCMT291 CHRM3 Muscarinic acetylcholine receptor M3 GPCR P20309
TCMT292 CHRM1 Muscarinic acetylcholine receptor M1 GPCR P11229
TCMT293 CHRM2 Muscarinic acetylcholine receptor M2 GPCR P08172
TCMT30 PTGS2 Cyclooxygenase-2 Oxidoreductase P35354
TCMT31 CYP2C19 Cytochrome P450 2C19 Oxidoreductase P33261
TCMT33 CYP3A4 Cytochrome P450 3A4 Oxidoreductase P08684
TCMT34 CYP2D6 Cytochrome P450 2D6 Oxidoreductase P10635
TCMT45 APP Beta amyloid A4 protein Unclassified P05067
TCMT6 NFKB1 Nuclear factor NF-kappa-B p105 subunit Transcription factor P19838
TCMT8 KDM4E Lysine-specific demethylase 4D-like Oxidoreductase B2RXH2
TCMT87 CYP2C9 Cytochrome P450 2C9 Oxidoreductase P11712


Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1393 Vibrio sp.
TCMT1455 Mycobacterium tuberculosis H37Rv

Ingredient Structrues

Ingredient ID: TCMC50
Formula: C8H15NO

Ingredient ID: TCMC2550
Formula: C15H24

Ingredient ID: TCMC2204
Formula: C9H6O3

Ingredient ID: TCMC2051
Formula: C10H8O4

Ingredient ID: TCMC200
Formula: C17H23NO3

Ingredient ID: TCMC1999
Formula: C21H24N2O3

Ingredient ID: TCMC1660
Formula: C21H24N2O3

Ingredient ID: TCMC1107
Formula: C17H23NO3

Properties

Ingredient ID Formulae Name MW AlogP MlogP XlogP # HBA # HBD PSA # Rotatable Bond # Ring # Heacy Atom Lipinski RO5 Violation
TCMC50 C8H15NO (1S,5R)-8-Methyl-8-Azabicyclo[3.2.1]Octan-3-Ol 141.12 -1.648 2.12 0.477 2 1 23.47 2 2 10 0
TCMC200 C17H23NO3 [(1S,5R)-8-Methyl-8-Azabicyclo[3.2.1]Octan-3-Yl] (2R)-3-Hydroxy-2-Phenylpropanoate 289.17 -1.8722 2.89 3.538 4 1 49.77 7 3 21 0
TCMC1107 C17H23NO3 Endo-Atropine 289.17 -1.8722 2.89 3.538 4 1 49.77 7 3 21 0
TCMC1660 C21H24N2O3 352.18 -0.6544 3.22 3.069 5 1 54.56 4 5 26 0
TCMC1999 C21H24N2O3 Rauwolfia Serpentina 352.18 -0.6544 3.22 3.069 5 1 54.56 4 5 26 0
TCMC2051 C10H8O4 Scopoletin 192.04 -0.2421 2.12 1.088 1 1 55.76 3 2 14 0
TCMC2204 C9H6O3 Umbelliferone 162.03 -0.1903 2.12 1.532 1 1 46.53 1 2 12 0
TCMC2550 C15H24 (+)-Germacrene D 204.19 2.7967 3.11 6.294 0 0 0 4 1 15 1

Download Data

All data can be downloaded by:

   → Selecting data type in the below download table
   → Then click the download button.
Data Section
Select to Download
1. General Information of the Component  
2. TCM Prescriptions with the Component  
3. Putative Targets  
4. Activity & References for Filtering Putative Targets  
5. Ingredient Data & Chemical Structure Information (Properties, InChI, InChIkey, SMILES, etc.)