TCM-ID Component

Component: Rhizoma dioscoreae nipponicae 广地龙

Description of the Component

Component ID	TCMH721
Latin Name	Rhizoma dioscoreae nipponicae
English Name	Earthworm
Chinese Pinyin Name	Guang Di Long
中文名	广地龙
TCM Properties	Cold,Salty
TCM Meridians	Bladder,Spleen,Liver
Therapeutic Class English	For calming liver and containing wind
Therapeutic Class Chinese	平肝息风
Functions	remove heat, arrest convulsions, remove obstruction from the collaterals, relieve asthma, and cause diuresis
Toxicity	NA
Geo-authentic habitats (道地产区)	NA
Reference	Chinese Pharmacopoeia (2015)
Barcode ID
Barcode Source

TCM Prescriptions with the Component

Prescription ID	Prescription English Name	Prescription Chinese Name
TCMFx2516	Anti-Bone Growth Drink
TCMFx3337	Feng Shi An Tai Tablets	风湿安泰片

Targeted Human Proteins by the Ingredient of Component

Target ID	Gene Symbol	Target Name	Target Class	Uniprot ID
TCMT3	ALOX15	Arachidonate 15-lipoxygenase	Oxidoreductase	P16050
TCMT318	HKDC1	Putative hexokinase HKDC1	Transferase	Q2TB90
TCMT8	KDM4E	Lysine-specific demethylase 4D-like	Oxidoreductase	B2RXH2

Targeted Pathogenic Microbes by the Ingredient of Component

Target ID	Target Name

Ingredient Structrues

Ingredient ID: TCMC1015
Formula: C11H10N2O

Common Name	Deoxyvasicinone
IUPAC Name	2,3-dihydro-1H-pyrrolo[2,1-b]quinazolin-9-one
Canonical SMILES	O=c1c2ccccc2nc2n1CCC2
Standard InCHI	InChI=1S/C11H10N2O/c14-11-8-4-1-2-5-9(8)12-10-6-3-7-13(10)11/h1-2,4-5H,3,6-7H2
Standard InCHIKey	VARHXCYGZKSOOO-UHFFFAOYSA-N
External Identifiers	ChEMBL [CHEMBL456881]; PubChem [68261];
Reference of Component-Ingredient Pair	N/A

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH1213	Dioscorea parviflora	Ku Liang Jiang	苦良姜
TCMH1167	Dioscorea hypoglauca	Jiu Niu Li	九牛力
TCMH276	Dioscorea septemloba	Chuan Bi Xie	川萆薢
TCMH285	Dioscorea nipponica	Chuan Long Shu Yu	穿龙薯蓣
TCMH535	Dioscorea zingiberensis	Dun Ye Shu Yu Gen Jing	盾叶薯蓣根茎
TCMH721	Rhizoma dioscoreae nipponicae	Guang Di Long	广地龙
TCMH1512	Isatis indigotica	Mu Da Qing Ye	木大青叶
TCMH294	Rhizoma dioscoreae nipponicae	Chuan Shan Long	穿山龙
TCMH456	Rhizoma dioscoreae nipponicae	Di Long	地龙
TCMH126	Isatis indigotica	Ban Lan	板蓝
TCMH127	Isatis indigotica	Ban Lan Gen	板蓝根
TCMH381	Isatis indigotica	Da Qing Ye	大青叶
TCMH1510	Isatis indigotica	Mu Ban Lan Gen	木板蓝根
TCMH170	Dioscorea hypoglauca	Bi Xie	萆薢

Properties

Ingredient ID	Formulae	Name	MW	AlogP	MlogP	XlogP	# HBA	# HBD	PSA	# Rotatable Bond	# Ring	# Heacy Atom	Lipinski RO5 Violation
TCMC1015	C11H10N2O	Deoxyvasicinone	186.08	-0.8417	2.34	1.937	3	0	32.67	0	3	14	0

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Data Section	Select to Download
1. General Information of the Component
2. TCM Prescriptions with the Component
3. Putative Targets
4. Activity & References for Filtering Putative Targets
5. Ingredient Data & Chemical Structure Information (Properties, InChI, InChIkey, SMILES, etc.)