TCM Putative Target References: TCMH313


Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
.
Ingredient ID & Structure Target ID Target Name Target Organism Activity Records & Reference
TCMC1409
TCMT22 Intestinal alkaline phosphatase Homo sapiens IC50: 5250 (nM), Ref: IC50: 8960 (nM), Ref:
TCMC1409
TCMT223 Aldose reductase Homo sapiens IC50: 4500 (nM), Ref: 22261024
TCMC1409
TCMT134 Carbonic anhydrase II Homo sapiens Ki: 6211.2 (nM), Ref: 26498393
Ki: 410 (nM), Ref: 26498393
TCMC1409
TCMT142 Carbonic anhydrase IV Homo sapiens Ki: 75.7 (nM), Ref: 26498393
TCMC1409
TCMT138 Carbonic anhydrase VII Homo sapiens Ki: 3.8 (nM), Ref: 26498393
TCMC1409
TCMT136 Carbonic anhydrase XII Homo sapiens Ki: 52.1 (nM), Ref: 26498393
Ki: 170 (nM), Ref: 26498393
TCMC2189
TCMT254 Carbonyl reductase [NADPH] 1 Homo sapiens IC50: 400 (nM), Ref: 19097799
Ki: 60 (nM), Ref: 19097799
TCMC1400
TCMT223 Aldose reductase Homo sapiens IC50: 720 (nM), Ref: 22261024
TCMC1365
TCMT307 HERG Homo sapiens IC50: 100 (nM), Ref: 21185626
TCMC1365
TCMT903 Glutamate [NMDA] receptor subunit epsilon 2 Homo sapiens IC50: 20 (nM), Ref: 24411196
Ki: 10 (nM), Ref: 25458498

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure Target ID Target Name Target Organism Activity Records & Reference
TCMC1206
TCMT1099 Neuraminidase Influenza A virus (A/Puerto Rico/8/1934(H1N1)) IC50: 21.25 (ug/ml), Ref: 20116898
TCMC2189
TCMT1093 Enoyl-acyl-carrier protein reductase Plasmodium falciparum IC50: 0.014 (ug/ml), Ref: 17765547
IC50: 73 (nM), Ref: 16198563
IC50: 73 (nM), Ref: 16466916
Ki: 7.29 (nM), Ref: 17263522
Ki: 28.31 (nM), Ref: 17263522
Ki: 52.71 (nM), Ref: 17263522
Ki: 30.54 (nM), Ref: 17263522
Ki: 71.02 (nM), Ref: 17263522
Ki: 0.0019 (nM), Ref: 17263522
Ki: 0.109 (nM), Ref: 17263522
Ki: 0.05206 (nM), Ref: 17263522
Ki: 0.2806 (nM), Ref: 17263522
Ki: 0.7983 (nM), Ref: 17263522
Ki: 1 (nM), Ref: 17263522
Ki: 8.25 (nM), Ref: 17263522
Ki: 8 (nM), Ref: 17263522
Ki: 10 (nM), Ref: 17263522
Ki: 13.72 (nM), Ref: 17263522
IC50: 66 (nM), Ref: 17477517
IC50: 73 (nM), Ref: 17567585
IC50: 70 (nM), Ref: 17485508
IC50: 73 (nM), Ref: 19217192
Ki: 50 (nM), Ref: 19217192
IC50: 70 (nM), Ref: 22082562
TCMC2189
TCMT1105 Enoyl-ACP reductase Plasmodium falciparum IC50: 0.014 (ug/ml), Ref: 20855214
TCMC1409
TCMT1463 Mycobacterium tuberculosis Mycobacterium tuberculosis H37Rv MIC: 94 (ug/ml), Ref: 15104489
TCMC1409
TCMT1447 Respiratory syncytial virus Respiratory syncytial virus IC50: 5.9 (ug/ml), Ref: 15104496
TCMC1409
TCMT1294 Human parainfluenza virus 3 Human parainfluenza virus 3 IC50: 23.4 (ug/ml), Ref: 15104496
TCMC1409
TCMT1346 Helicobacter pylori Helicobacter pylori MIC: 25 (ug/ml), Ref: 12762812
TCMC1409
TCMT1443 Leishmania amazonensis Leishmania amazonensis IC50: 0.78 (ug/ml), Ref: 10.1039/C5MD00481K
TCMC1206
TCMT1465 Entamoeba histolytica Entamoeba histolytica IC50: 44.7 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC2189
TCMT1246 Escherichia coli Escherichia coli MIC: 0.3 (ug/ml), Ref: 14736233
MIC: 0.2 (ug/ml), Ref: 19933806
MIC: 3 (ug/ml), Ref: 19933806
MIC: 4 (ug/ml), Ref: 19933806
MIC: 0.2 (ug/ml), Ref: 18180352
MIC: 0.125 (ug/ml), Ref: 23092194
MIC: 2 (ug/ml), Ref: 23466234
TCMC2189
TCMT1218 Staphylococcus aureus Staphylococcus aureus MIC: 0.06 (ug/ml), Ref: 12109908
MIC: 0.03 (ug/ml), Ref: 11514139
MIC: 0.125 (ug/ml), Ref: 17095231
MIC: 0.063 (ug/ml), Ref: 17713898
MIC: 20 (ug/ml), Ref: 21821415
MIC: 0.031 (ug/ml), Ref: 23092194
MIC: 4 (ug/ml), Ref: 23466234
MIC: 0.01 (ug/ml), Ref: 24332629
MIC: 0.391 (ug/ml), Ref: 26343826
TCMC2189
TCMT1177 Haemophilus influenzae Haemophilus influenzae MIC: 0.06 (ug/ml), Ref: 12109908
TCMC2189
TCMT1462 Streptococcus mutans Streptococcus mutans MIC: 16 (ug/ml), Ref: 17220400
MIC: 4 (ug/ml), Ref: 20427099
TCMC2189
TCMT1217 Bacillus anthracis Bacillus anthracis MIC: 3.1 (ug/ml), Ref: 18499454
TCMC2189
TCMT1463 Mycobacterium tuberculosis Mycobacterium tuberculosis H37Rv MIC: 5 (ug/ml), Ref: 18538450
MIC: 5 (ug/ml), Ref: 22079026
TCMC2189
TCMT1178 Actinomyces viscosus Actinomyces viscosus MIC: 4 (ug/ml), Ref: 20427099
TCMC2189
TCMT1182 Streptococcus sanguinis Streptococcus sanguinis MIC: 4 (ug/ml), Ref: 20427099
TCMC2189
TCMT1211 Fusobacterium nucleatum Fusobacterium nucleatum MIC: 2 (ug/ml), Ref: 20427099
TCMC2189
TCMT1232 Pseudomonas aeruginosa Pseudomonas aeruginosa MIC: 1 (ug/ml), Ref: 19933806
TCMC2189
TCMT1224 Proteus mirabilis Proteus mirabilis MIC: 0.2 (ug/ml), Ref: 18180352
MIC: 40 (ug/ml), Ref: 18180352
MIC: 2 (ug/ml), Ref: 18180352
MIC: 5 (ug/ml), Ref: 18180352
MIC: 0.1 (ug/ml), Ref: 18180352
MIC: 20 (ug/ml), Ref: 18180352
MIC: 10 (ug/ml), Ref: 18180352
MIC: 0.8 (ug/ml), Ref: 18180352
TCMC2189
TCMT1174 Mycobacterium bovis BCG Mycobacterium bovis BCG MIC: 8 (ug/ml), Ref: 19564371
TCMC2189
TCMT1463 Mycobacterium tuberculosis Mycobacterium tuberculosis MIC: 5 (ug/ml), Ref: 18538450
MIC: 5 (ug/ml), Ref: 22079026
TCMC2189
TCMT1229 Enterococcus faecalis Enterococcus faecalis MIC: 2 (ug/ml), Ref: 23092194
TCMC2189
TCMT1455 Mycobacterium tuberculosis H37Rv Mycobacterium tuberculosis H37Rv MIC: 10 (ug/ml), Ref: 24292339
MIC: 10 (ug/ml), Ref: 25771110
TCMC2189
TCMT1286 Bacillus cereus Bacillus cereus MIC: 0.01 (ug/ml), Ref: 24332629
TCMC2189
TCMT1172 Staphylococcus aureus subsp. aureus RN4220 Staphylococcus aureus subsp. aureus RN4220 MIC: 0.01 (ug/ml), Ref: 24332629
TCMC2189
TCMT1140 Enoyl-[acyl-carrier-protein] reductase Staphylococcus aureus IC50: 70 (nM), Ref: 12699381
TCMC2189
TCMT1142 Enoyl-[acyl-carrier-protein] reductase [NADPH] Staphylococcus aureus IC50: 59 (nM), Ref: 23092194