Prescription Description
| Prescription ID | TCMF68 |
| Pinyin Name | Qing Yan Run Hou Wan |
| Chinese Name | 清咽润喉丸 |
| English Name | Qing Yan Run Hou Pills |
| Function Description | 上呼吸道感染, 病毒性感冒, 急性化脓性扁桃体, 急性咽炎, 急性气管炎, 高热 |
| Indications | Common cold disorder, Common cold, Upper respiratory infection(uri) |
| Disease ICD-11 Category |
SA60 [Common cold disorder (TM1), 感冒 (TM1)
]; CA00 [Acute nasopharyngitis, 急性鼻咽炎 ]; CA0Z [Upper respiratory tract disorders, unspecified, 上呼吸道疾患，未特指的 ]; |
| Human Tissues Associated with Indication | Lung, Bronchus, Blood |
| Reference | Chinese pharmacopoeia (2015) |
| Reference Book/link | ISBN 978-7-5067-7337-9 |
Prescription Components
| Component ID | Latin Name | Chinese Name | Component Quantity | Barcode |
|---|---|---|---|---|
| TCMH1870 | Belamcanda chinensis | 射干 | TCMH1870 | |
| TCMH1080 | Platycodon grandiflorum | 桔梗 | TCMH1080 | ITSAJ4293-14 |
| TCMH2641 | Gardenia jasminoides | 栀子 | TCMH2641 | ITSAJ4473-14 |
| TCMH1683 | Canarium album | 青果 | TCMH1683 | ITSAM870-14 |
| TCMH1423 | Ophiopogon japonicus | 麦冬 | TCMH1423 | ITSAJ4140-14 |
| TCMH2624 | Anemarrhena asphodeloides | 知母 | TCMH2624 | GBVA3255-11, GBVU1201-13 |
| TCMH104 | Paeonia lactiflora | 白芍 | TCMH104 | ITSAH2416-14 |
| TCMH628 | Glycyrrhiza uralensis | 甘草 | TCMH628 | ITSAM892-14 |
| TCMH1999 | Bubalus bubalis | 水牛角浓缩粉 | TCMH1999 | GBMA0080-06 |
| TCMH1814 | Sophora subprostrata | 山豆根 | TCMH1814 | |
| TCMH1060 | Bombyx batryticatus | 僵蚕 | TCMH1060 | |
| TCMH1513 | Paeonia moutan | 牡丹皮 | TCMH1513 | |
| TCMH1102 | Tinospora capillipes | 金果榄 | TCMH1102 | ITSAP1073-14 |
| TCMH2343 | Scrophularia ningpoensis | 玄参 | TCMH2343 | ITSAO4295-14 |
| TCMH451 | Rehmannia glutinosa | 地黄 | TCMH451 | ITSAH4578-14 |
| TCMH2596 | Fritillaria verticillata | 浙贝母 | TCMH2596 | |
| TCMH183 | Dryobalanops aromatica | 冰片 | TCMH183 | GBVK4926-11 |
Targeted Human Proteins by the Ingredients of Prescription
| Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
|---|---|---|---|---|
| TCMT101 | PTPN1 | Protein-tyrosine phosphatase 1B | Hydrolase | P18031 |
| TCMT112 | ADORA3 | Adenosine A3 receptor | GPCR | P0DMS8 |
| TCMT126 | TERT | Telomerase reverse transcriptase | Transferase | O14746 |
| TCMT127 | PARP1 | Poly [ADP-ribose] polymerase-1 | Transferase | P09874 |
| TCMT128 | TNKS2 | Tankyrase-2 | Transferase | Q9H2K2 |
| TCMT129 | TNKS | Tankyrase-1 | Transferase | O95271 |
| TCMT130 | ALOX5 | Arachidonate 5-lipoxygenase | Oxidoreductase | P09917 |
| TCMT131 | ACHE | Acetylcholinesterase | Hydrolase | P22303 |
| TCMT133 | CA1 | Carbonic anhydrase I | Lyase | P00915 |
| TCMT134 | CA2 | Carbonic anhydrase II | Lyase | P00918 |
Showing 1 to 10 of 120 entries
Targeted Pathogenic Microbes by the Ingredients of Prescription
| Target ID | Target Name |
|---|---|
| TCMT1170 | Enterobacter cloacae |
| TCMT1175 | Human immunodeficiency virus |
| TCMT1176 | Streptococcus pneumoniae |
| TCMT1177 | Haemophilus influenzae |
| TCMT1178 | Actinomyces viscosus |
| TCMT1179 | Escherichia coli ATCC 8739 |
| TCMT1181 | Mycobacterium tuberculosis H37Ra |
| TCMT1182 | Streptococcus sanguinis |
| TCMT1186 | Plasmodium yoelii yoelii |
| TCMT1189 | Pseudomonas fluorescens |
Showing 1 to 10 of 71 entries
Gene Ontology Associated to Targeted Human Proteins
| GO Term | GO Name | Enriched Genes | Log10 Adjusted P-value |
|---|---|---|---|
| [BP] GO:0000302 | response to reactive oxygen species | AKR1B1, AXL, BCL2, CYP1B1, EGFR, MMP9, SRC | 3.12499 |
| [BP] GO:0001101 | response to acid chemical | AKR1B1, DNMT1, EGFR, FABP3, HSD17B2, KDR, MMP2, NR1H4, PTGS2, SRC | 3.88631 |
| [BP] GO:0001503 | ossification | ALPL, BCL2, EGFR, MMP2, MMP9, TEK, THRA | 4.16849 |
| [BP] GO:0001505 | regulation of neurotransmitter levels | ACHE, CYP1B1, EGFR, INSR, MAOB, PTGS2, SMAD3 | 2.25705 |
| [BP] GO:0001525 | angiogenesis | CYP1B1, KDR, MMP2, PIK3CA, PIK3CB, PTGS2, TEK | 2.24831 |
| [BP] GO:0001666 | response to hypoxia | ADORA1, BCL2, CYP1A1, HSD11B2, MMP2, PPARA, PTGS2, SMAD3, SRC, TEK, TERT | 5.58954 |
| [BP] GO:0001676 | long-chain fatty acid metabolic process | CYP1A1, CYP1A2, CYP1B1, PTGS1, PTGS2 | 2.41992 |
| [BP] GO:0001775 | cell activation | ADRA2A, ADRA2C, ALOX5, APP, AXL, BCL2, EGFR, FLT3, FUT7, HSPA1A, KIT, MMP9, PIK3CA, PIK3CB, SMAD3, SRC | 3.54362 |
| [BP] GO:0001932 | regulation of protein phosphorylation | ADORA1, ADRA2A, ADRA2C, APP, BCL2, CDC25B, DUSP3, EGFR, FABP4, FLT3, IGF1R, INSR, KDR, KIT, MMP9, PDE5A, PIK3CA, PIK3CB, PTGS2, PTPN1, SRC, TEK, XDH | 5.64583 |
| [BP] GO:0001934 | positive regulation of protein phosphorylation | ADORA1, ADRA2A, ADRA2C, APP, BCL2, CDC25B, EGFR, FLT3, INSR, KDR, KIT, MMP9, PDE5A, PIK3CA, PIK3CB, PTGS2, PTPN1, SRC, TEK, XDH | 6.21852 |
Showing 1 to 10 of 545 entries
KEGG Pathways Associated to Targeted Human Proteins
| KEGG Pathway ID | Enriched Genes | Log10 Adjusted P-value |
|---|---|---|
| ABC transporters_Homo sapiens_hsa02010 | ABCB1 | 0.6714 |
| Acute myeloid leukemia_Homo sapiens_hsa05221 | PIK3CA, FLT3, KIT, PIM1, PIK3CB | 4.5384 |
| Adherens junction_Homo sapiens_hsa04520 | PTPN1, SMAD3, CSNK2A1, SRC, INSR, MET, EGFR, IGF1R | 7.5501 |
| Adipocytokine signaling pathway_Homo sapiens_hsa04920 | PPARA | 0.5411 |
| Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | PIK3CA, BCL2, PIK3CB | 1.3721 |
| AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | SMAD3, PIK3CA, MMP2, BCL2, PIM1, PIK3CB, F3 | 5.534 |
| Alcoholism_Homo sapiens_hsa05034 | MAOB | 0.2708 |
| Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | HSD11B2, PIK3CA, INSR, PIK3CB | 3.9731 |
| Alzheimer's disease_Homo sapiens_hsa05010 | BACE1, APP | 0.694 |
| Amoebiasis_Homo sapiens_hsa05146 | PIK3CA, PIK3CB | 1.0128 |
Showing 1 to 10 of 170 entries
Target Exprsssion in Healthy Human Tissues (protein & mRNA level)
Protein expression data was from the "Human Proteome Map" datasetmRNA expression data was from the "GTEx" dataset
Average Target Expression (Fold Change) in Multiple Disease Conditions
Fold Change with Corresponding Normal SamplesClick each cell within the heatmap to access gene expression of individual patient samples