Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
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Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC2188	TCMT223	Aldose reductase	Homo sapiens	IC50: 2030 (nM), Ref: 10.1007/s00044-010-9412-4
TCMC1396	TCMT689	Protein-glutamine gamma-glutamyltransferase	Homo sapiens	IC50: 8000 (nM), Ref: 21215619
TCMC2196	TCMT30	Cyclooxygenase-2	Homo sapiens	IC50: 64 (nM), Ref: 22819942 IC50: 64 (nM), Ref: 23146282
TCMC2196	TCMT130	Arachidonate 5-lipoxygenase	Homo sapiens	IC50: 150 (nM), Ref: 22819942
TCMC2196	TCMT336	Indoleamine 2,3-dioxygenase	Homo sapiens	IC50: 53.7 (nM), Ref: 24099220 IC50: 7150 (nM), Ref: 24099220 Ki: 4810 (nM), Ref: 24099220
TCMC1202	TCMT135	Carbonic anhydrase XIV	Homo sapiens	Ki: 7030 (nM), Ref: 20185318
TCMC1202	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 7780 (nM), Ref: 20185318
TCMC1202	TCMT137	Carbonic anhydrase IX	Homo sapiens	Ki: 6990 (nM), Ref: 20185318
TCMC1202	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 6070 (nM), Ref: 20185318
TCMC1202	TCMT139	Carbonic anhydrase VI	Homo sapiens	Ki: 6130 (nM), Ref: 20185318
TCMC1202	TCMT140	Carbonic anhydrase VB	Homo sapiens	Ki: 9970 (nM), Ref: 20185318
TCMC1202	TCMT141	Carbonic anhydrase VA	Homo sapiens	Ki: 4080 (nM), Ref: 20185318
TCMC1202	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 9800 (nM), Ref: 20185318
TCMC1202	TCMT143	Carbonic anhydrase III	Homo sapiens	Ki: 7490 (nM), Ref: 20185318
TCMC1202	TCMT134	Carbonic anhydrase II	Homo sapiens	Ki: 2250 (nM), Ref: 20185318
TCMC1202	TCMT133	Carbonic anhydrase I	Homo sapiens	Ki: 3200 (nM), Ref: 20185318
TCMC1202	TCMT822	Alpha-(1,3)-fucosyltransferase 7	Homo sapiens	IC50: 60 (nM), Ref: 10.1039/C4MD00086B
TCMC983	TCMT236	Estrogen receptor beta	Homo sapiens	IC50: 2800 (nM), Ref: 15887952 IC50: 2800 (nM), Ref: 15887952 IC50: 1200 (nM), Ref: 12502307 IC50: 2800 (nM), Ref:
TCMC983	TCMT162	UDP-glucuronosyltransferase 1-1	Homo sapiens	IC50: 7300 (nM), Ref: 21030469
TCMC983	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 718.7 (nM), Ref: 26498393
TCMC983	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 4.2 (nM), Ref: 26498393
TCMC983	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 56.4 (nM), Ref: 26498393
TCMC1377	TCMT186	Monoamine oxidase B	Homo sapiens	Ki: 3000 (nM), Ref: 16137882 Ki: 3000 (nM), Ref: 19342233 IC50: 7943.28 (nM), Ref: 20934874 Ki: 5340 (nM), Ref: 21134756 Ki: 3000 (nM), Ref: 21778064 Ki: 2000 (nM), Ref: 24140951
TCMC1377	TCMT208	Monoamine oxidase A	Homo sapiens	Ki: 8380 (nM), Ref: 21134756
TCMC804	TCMT280	Aldo-keto reductase family 1 member B10	Homo sapiens	IC50: 2000 (nM), Ref: 21561086
TCMC1734	TCMT254	Carbonyl reductase [NADPH] 1	Homo sapiens	Ki: 3430 (nM), Ref: 19097799
TCMC1734	TCMT65	Estradiol 17-beta-dehydrogenase 1	Homo sapiens	IC50: 4960 (nM), Ref: 18533708
TCMC1734	TCMT156	Cytochrome P450 19A1	Homo sapiens	IC50: 2.9 (nM), Ref: 20413308 IC50: 230 (nM), Ref: 22115839 IC50: 230 (nM), Ref: 23142320 IC50: 1200 (nM), Ref: 23994869 IC50: 3300 (nM), Ref: 24074257 IC50: 1200 (nM), Ref: 24992702 IC50: 5100 (nM), Ref: 27155469 IC50: 1000 (nM), Ref: 27155469
TCMC1734	TCMT257	Cytochrome P450 1B1	Homo sapiens	IC50: 3656 (nM), Ref: 20696580
TCMC1734	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 79.5 (nM), Ref: 26498393
TCMC1734	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 4.3 (nM), Ref: 26498393
TCMC1734	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 44.3 (nM), Ref: 26498393
TCMC811	TCMT254	Carbonyl reductase [NADPH] 1	Homo sapiens	Ki: 2030 (nM), Ref: 19097799
TCMC811	TCMT66	Estradiol 17-beta-dehydrogenase 2	Homo sapiens	IC50: 9900 (nM), Ref: 18533708
TCMC811	TCMT156	Cytochrome P450 19A1	Homo sapiens	IC50: 10.2 (nM), Ref: 20413308
TCMC811	TCMT142	Carbonic anhydrase IV	Homo sapiens	Ki: 7078.5 (nM), Ref: 26498393
TCMC811	TCMT138	Carbonic anhydrase VII	Homo sapiens	Ki: 371.5 (nM), Ref: 26498393
TCMC811	TCMT136	Carbonic anhydrase XII	Homo sapiens	Ki: 52.5 (nM), Ref: 26498393
TCMC1496	TCMT63	Peroxisome proliferator-activated receptor alpha	Homo sapiens	IC50: 1200 (nM), Ref: 10.1007/s00044-008-9102-7 IC50: 1200 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1496	TCMT67	Peroxisome proliferator-activated receptor gamma	Homo sapiens	IC50: 6000 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1496	TCMT164	Cyclooxygenase-1	Homo sapiens	Ki: 4000 (nM), Ref: 24088053
TCMC1063	TCMT277	Solute carrier organic anion transporter family member 1B3	Homo sapiens	Ki: 1430 (nM), Ref: 23396419 Ki: 4550 (nM), Ref: 23396419 Ki: 8290 (nM), Ref: 23396419 Ki: 1030 (nM), Ref: 23396419
TCMC1403	TCMT223	Aldose reductase	Homo sapiens	IC50: 1910 (nM), Ref: 10.1007/s00044-010-9412-4

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure	Target ID	Target Name	Target Organism	Activity Records & Reference
TCMC2233	TCMT1099	Neuraminidase	Influenza A virus (A/Puerto Rico/8/1934(H1N1))	IC50: 20.85 (ug/ml), Ref: 20116898
TCMC983	TCMT1099	Neuraminidase	Influenza A virus (A/Puerto Rico/8/1934(H1N1))	IC50: 9.43 (ug/ml), Ref: 20116898
TCMC855	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 4.2 (ug/ml), Ref: 19299148
TCMC2196	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC: 10 (ug/ml), Ref: 22819942 MIC: 0.5 (ug/ml), Ref: 26253635
TCMC2196	TCMT1455	Mycobacterium tuberculosis H37Rv	Mycobacterium tuberculosis H37Rv	MIC: 1 (ug/ml), Ref: 23360475 MIC: 1 (ug/ml), Ref: 26253635
TCMC2196	TCMT1439	Mycobacterium smegmatis	Mycobacterium smegmatis	MIC: 6 (ug/ml), Ref: 26253635
TCMC1186	TCMT1246	Escherichia coli	Escherichia coli	MIC: 100 (ug/ml), Ref: 3430167
TCMC1186	TCMT1284	Penicillium expansum	Penicillium expansum	MIC: 50 (ug/ml), Ref: 3430167
TCMC1202	TCMT1178	Actinomyces viscosus	Actinomyces viscosus	MIC: 78 (ug/ml), Ref: 8904847
TCMC1202	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 14.8 (ug/ml), Ref: 15844943
TCMC801	TCMT1438	Plasmodium falciparum	Plasmodium falciparum	IC50: 32 (ug/ml), Ref: 15844943
TCMC801	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 52.3 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC804	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis H37Rv	MIC: 32 (ug/ml), Ref: 15387646 MIC: 62 (ug/ml), Ref: 23356207
TCMC804	TCMT1181	Mycobacterium tuberculosis H37Ra	Mycobacterium tuberculosis H37Ra	MIC: 25 (ug/ml), Ref: 22280816
TCMC804	TCMT1463	Mycobacterium tuberculosis	Mycobacterium tuberculosis	MIC: 32 (ug/ml), Ref: 15387646 MIC: 62 (ug/ml), Ref: 23356207
TCMC1734	TCMT1465	Entamoeba histolytica	Entamoeba histolytica	IC50: 92.24 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC1063	TCMT1251	Candida albicans	Candida albicans	MIC: 1.56 (ug/ml), Ref: 3373231 MIC: 3.12 (ug/ml), Ref: 3373231 MIC: 6.25 (ug/ml), Ref: 3373231 MIC: 2 (ug/ml), Ref: 15921418
TCMC1063	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	MIC: 25 (ug/ml), Ref: 3373231 MIC: 1 (ug/ml), Ref: 15921418
TCMC1063	TCMT1243	Aspergillus flavus	Aspergillus flavus	MIC: 100 (ug/ml), Ref: 3373231
TCMC1063	TCMT1176	Streptococcus pneumoniae	Streptococcus pneumoniae	MIC: 32 (ug/ml), Ref: 15921418
TCMC1403	TCMT1229	Enterococcus faecalis	Enterococcus faecalis	MIC: 25 (ug/ml), Ref: 17027268
TCMC1403	TCMT1226	Klebsiella pneumoniae	Klebsiella pneumoniae	MIC: 25 (ug/ml), Ref: 17027268
TCMC1403	TCMT1246	Escherichia coli	Escherichia coli	MIC: 25 (ug/ml), Ref: 17027268
TCMC1403	TCMT1218	Staphylococcus aureus	Staphylococcus aureus	MIC: 25 (ug/ml), Ref: 17027268
TCMC1403	TCMT1458	Filobasidiella neoformans	Cryptococcus neoformans	MIC: 25 (ug/ml), Ref: 17027268
TCMC791	TCMT1221	Human herpesvirus 4	Human herpesvirus 4	IC50: 12.7 (nM), Ref: 17503850