TCM-ID Component

Component: Fissistigma oldhamii 钻山风

Description of the Component

Component ID	TCMH2747
Latin Name	Fissistigma oldhamii
English Name	NA
Chinese Pinyin Name	Zuan Shan Feng
中文名	钻山风
TCM Properties
TCM Meridians
Therapeutic Class English
Therapeutic Class Chinese
Functions
Toxicity	NA
Geo-authentic habitats (道地产区)	NA
Reference	Chinese Pharmacopoeia (2015)
Barcode ID
Barcode Source

TCM Prescriptions with the Component

Prescription ID	Prescription English Name	Prescription Chinese Name
TCMFx901	Zuan Shan Feng Syrup	钻山风糖浆
TCMFx6851	Zuan Shan Feng Syrup	钻山风糖浆

Targeted Human Proteins by the Ingredient of Component

Target ID	Gene Symbol	Target Name	Target Class	Uniprot ID
TCMT160	HTR7	Serotonin 7 (5-HT7) receptor	GPCR	P34969
TCMT2	MAPT	Microtubule-associated protein tau	Unclassified	P10636
TCMT31	CYP2C19	Cytochrome P450 2C19	Oxidoreductase	P33261
TCMT33	CYP3A4	Cytochrome P450 3A4	Oxidoreductase	P08684
TCMT34	CYP2D6	Cytochrome P450 2D6	Oxidoreductase	P10635
TCMT36	HTR1A	Serotonin 1a (5-HT1a) receptor	GPCR	P08908
TCMT37	HTR2A	Serotonin 2a (5-HT2a) receptor	GPCR	P28223
TCMT8	KDM4E	Lysine-specific demethylase 4D-like	Oxidoreductase	B2RXH2
TCMT87	CYP2C9	Cytochrome P450 2C9	Oxidoreductase	P11712

Targeted Pathogenic Microbes by the Ingredient of Component

Target ID	Target Name
TCMT1223	Staphylococcus epidermidis
TCMT1438	Plasmodium falciparum

Ingredient Structrues

Ingredient ID: TCMC2577
Formula: C19H15NO4

Common Name	Homomoschatoline
IUPAC Name	n.a.
Canonical SMILES	COc1c(OC)c(OC)c2c3c1c1ccccc1C(=O)c3ncc2
Standard InCHI	InChI=1S/C19H15NO4/c1-22-17-12-8-9-20-15-13(12)14(18(23-2)19(17)24-3)10-6-4-5-7-11(10)16(15)21/h4-9H,1-3H3
Standard InCHIKey	WXGQWNXTPSGPIX-UHFFFAOYSA-N
External Identifiers	ChEMBL [CHEMBL227533]; PubChem [145779];
Reference of Component-Ingredient Pair	N/A

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH2747	Fissistigma oldhamii	Zuan Shan Feng	钻山风

Ingredient ID: TCMC1383
Formula: C19H21NO4

Common Name	Isoboldine
IUPAC Name	(6aS)-2,10-dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline-1,9-diol
Canonical SMILES	COc1cc2c(cc1O)C[C@H]1c3c2c(O)c(OC)cc3CCN1C
Standard InCHI	InChI=1S/C19H21NO4/c1-20-5-4-10-8-16(24-3)19(22)18-12-9-15(23-2)14(21)7-11(12)6-13(20)17(10)18/h7-9,13,21-22H,4-6H2,1-3H3/t13-/m0/s1
Standard InCHIKey	LINHZVMHXABQLB-ZDUSSCGKSA-N
External Identifiers	ChEMBL [CHEMBL462880]; PubChem [133323];
Reference of Component-Ingredient Pair	N/A

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH1825	Litsea cubeba	Shan Jiang Zi	山姜子
TCMH2747	Fissistigma oldhamii	Zuan Shan Feng	钻山风
TCMH2664	Hypocrella bambusae	Zhu Hong Jun	竹红菌
TCMH2101	Eupatorium rebaudianum	Tian Ye Ju	甜叶菊
TCMH2282	Citrus medica	Xiang Yuan Pi	香橼皮
TCMH2281	Citrus medica	Xiang Yuan	香橼
TCMH511	Litsea cubeba	Dou Chi Jiang	豆豉姜
TCMH1812	Litsea cubeba	Shan Cang Zi	山苍子

Ingredient ID: TCMC1258
Formula: C21H25NO4

Common Name	Glaucine
IUPAC Name	(6aS)-1,2,9,10-tetramethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline
Canonical SMILES	COc1cc2c(cc1OC)C[C@H]1c3c2c(OC)c(OC)cc3CCN1C
Standard InCHI	InChI=1S/C21H25NO4/c1-22-7-6-12-9-18(25-4)21(26-5)20-14-11-17(24-3)16(23-2)10-13(14)8-15(22)19(12)20/h9-11,15H,6-8H2,1-5H3/t15-/m0/s1
Standard InCHIKey	RUZIUYOSRDWYQF-HNNXBMFYSA-N
External Identifiers	ChEMBL [CHEMBL228082]; PubChem [16754];
Reference of Component-Ingredient Pair	15938142

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH2515	Papaver somniferum	Ying Su Ke	罂粟壳
TCMH2747	Fissistigma oldhamii	Zuan Shan Feng	钻山风
TCMH2376	Corydalis yanhusuo	Yan Hu Suo	延胡索
TCMH1489	Papaver somniferum	Mi Ying Su Ke	蜜罂粟壳
TCMH2514	Papaver somniferum	Ying Su	罂粟

Properties

Ingredient ID	Formulae	Name	MW	AlogP	MlogP	XlogP	# HBA	# HBD	PSA	# Rotatable Bond	# Ring	# Heacy Atom	Lipinski RO5 Violation
TCMC1258	C21H25NO4	Glaucine	355.18	0.1875	3.22	2.237	1	0	40.16	9	4	26	0
TCMC1383	C19H21NO4	Isoboldine	327.15	-0.6295	3	1.199	1	2	62.16	7	4	24	0
TCMC2577	C19H15NO4	Homomoschatoline	321.1	-0.4192	3	2.904	2	0	57.65	6	4	24	0

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Data Section	Select to Download
1. General Information of the Component
2. TCM Prescriptions with the Component
3. Putative Targets
4. Activity & References for Filtering Putative Targets
5. Ingredient Data & Chemical Structure Information (Properties, InChI, InChIkey, SMILES, etc.)