| GO Term |
GO Name |
Enriched Genes |
Log10 Adjusted P-value |
|
[BP] GO:0008152 |
metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, AURKB, AXL, BCL2, CA1, CA12, CA2, CA4, CA6, CA7, CA9, CBR1, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DHFR, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GSK3B, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, IDO1, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIM1, PPARA, PTGS2, PTPN1, PTPRS, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1, TYR, XDH |
12.2644 |
|
[BP] GO:1901700 |
response to oxygen-containing compound
|
AKR1B1, ALPL, AXL, BCL2, CA9, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DHFR, EGFR, ESR1, ESRRA, FABP3, GSK3B, HMGCR, HSD11B2, HSD17B2, IDO1, IGF1R, INSR, MMP2, MMP9, PPARA, PTGS2, RORC, SRC, TEK, TYR |
11.5376 |
|
[BP] GO:0010033 |
response to organic substance
|
AKR1B1, ALOX15, ALPL, AXL, BCL2, CA2, CA9, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DHFR, EGFR, ESR1, ESRRA, FABP3, FABP4, FLT3, GSK3B, HMGCR, HSD11B2, HSD17B2, HSPA1A, IDO1, IGF1R, INSR, KDR, MMP2, PPARA, PTGS2, RORC, SMAD3, SRC, TEK, TYR |
11.4342 |
|
[BP] GO:0006629 |
lipid metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, CBR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, EGFR, ESR1, FABP3, FABP4, FUT7, GBA2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, MET, PPARA, PTGS2 |
11.3958 |
|
[BP] GO:0042221 |
response to chemical
|
ABCB1, AKR1B1, ALOX15, ALPL, AXL, BCL2, CA2, CA9, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DHFR, EGFR, ESR1, ESRRA, FABP3, FABP4, FLT3, GSK3B, HMGCR, HSD11B2, HSD17B2, HSPA1A, IDO1, IGF1R, INSR, KDR, MMP2, MMP9, PPARA, PTGS2, RORC, SMAD3, SRC, TEK, TOP1, TYR |
11.0303 |
|
[BP] GO:0044281 |
small molecule metabolic process
|
AKR1B1, AKR1B10, ALOX15, ALOX5, AOX1, CA1, CA12, CA2, CA4, CA6, CA7, CA9, CBR1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DHFR, FABP3, FUT7, GBA2, HMGCR, HSPA1A, IDO1, PIM1, PPARA, PTGS2, TYR, XDH |
10.1277 |
|
[BP] GO:0008202 |
steroid metabolic process
|
AKR1B1, AKR1B10, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP3A4, ESR1, GBA2, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
9.90881 |
|
[BP] GO:0055114 |
oxidation-reduction process
|
AKR1B1, AKR1B10, ALOX15, ALOX5, AOX1, CBR1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DHFR, GSK3B, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, IDO1, PTGS2, TYR, XDH |
9.89593 |
|
[BP] GO:0065008 |
regulation of biological quality
|
ABCB1, ACHE, ADORA1, AKR1B1, ALOX15, AURKB, AXL, BCL2, CA12, CA2, CA7, CDK6, CYP19A1, CYP1A1, CYP1B1, CYP3A4, DHFR, EGFR, ESR1, F10, F3, FABP3, FABP4, FLT3, GPR35, GSK3B, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, INSR, KDR, MET, PPARA, PTGS2, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
9.89593 |
|
[BP] GO:0010647 |
positive regulation of cell communication
|
ADORA1, AKR1B1, ALOX15, AXL, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, EGFR, F10, F3, FLT3, GPR35, GSK3B, HMGCR, HSPA1A, INSR, KDR, MET, MMP12, MMP9, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
9.89593 |
|
[BP] GO:0023056 |
positive regulation of signaling
|
ADORA1, AKR1B1, ALOX15, AXL, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, EGFR, F10, F3, FLT3, GPR35, GSK3B, HMGCR, HSPA1A, INSR, KDR, MET, MMP12, MMP9, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
9.87439 |
|
[BP] GO:0044237 |
cellular metabolic process
|
ACHE, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, AURKB, AXL, BCL2, CA1, CA12, CA2, CA4, CA6, CA7, CA9, CBR1, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DHFR, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, FABP3, FABP4, FLT3, FUT7, GBA2, GSK3B, HMGCR, HSD17B1, HSD17B2, HSPA1A, IDO1, IGF1R, INSR, KDR, MET, MMP1, MMP2, NUAK1, PIM1, PPARA, PTGS2, PTPN1, PTPRS, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1, TYR, XDH |
9.55912 |
|
[BP] GO:0042127 |
regulation of cell proliferation
|
ADORA1, ADORA3, AKR1B1, BCL2, CDC25B, CDK6, CSNK2A1, CYP1B1, EGFR, ESR1, ESRRA, F3, FABP3, FLT3, HMGCR, HSPA1A, IDO1, IGF1R, INSR, KDR, MMP12, MMP2, MMP9, NUAK1, PIM1, PTGS2, SMAD3, SRC, TEK, XDH |
9.21644 |
|
[BP] GO:0019748 |
secondary metabolic process
|
AKR1B1, AKR1B10, BCL2, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, TYR |
9.21644 |
|
[BP] GO:0033993 |
response to lipid
|
ALPL, AXL, BCL2, CA2, CA9, CDK6, CSNK2A1, CYP1A1, CYP1A2, EGFR, ESR1, ESRRA, FABP3, FLT3, HSD11B2, HSD17B2, IDO1, PTGS2, RORC, SRC, TYR |
9.07702 |
|
[BP] GO:0044238 |
primary metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, AURKB, AXL, BCL2, CBR1, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DHFR, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GSK3B, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, IDO1, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIM1, PPARA, PTGS2, PTPN1, PTPRS, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1, TYR, XDH |
9.06526 |
|
[BP] GO:0006730 |
one-carbon metabolic process
|
CA1, CA12, CA2, CA4, CA6, CA7, CA9, DHFR |
8.82814 |
|
[BP] GO:0009967 |
positive regulation of signal transduction
|
ADORA1, AKR1B1, ALOX15, AXL, BCL2, CSNK2A1, CYP1B1, EGFR, F10, F3, FLT3, GPR35, GSK3B, HMGCR, HSPA1A, INSR, KDR, MET, MMP12, MMP9, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
8.4917 |
|
[BP] GO:0015701 |
bicarbonate transport
|
CA1, CA12, CA14, CA2, CA4, CA6, CA7, CA9 |
8.10964 |
|
[BP] GO:0080134 |
regulation of response to stress
|
ABCB1, ADORA1, CDK6, CYP19A1, DHFR, DUSP3, EGFR, ESR1, F3, FABP4, GSK3B, HMGCR, HSPA1A, IDO1, IGF1R, MET, MMP12, MMP2, NUAK1, PPARA, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TEK, XDH |
8.08325 |
|
[BP] GO:0048522 |
positive regulation of cellular process
|
ACHE, ADORA1, AKR1B1, ALOX15, AURKB, AXL, BCL2, CA2, CA7, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FLT3, GPR35, GSK3B, HMGCR, HSPA1A, IDO1, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, PIM1, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
7.97513 |
|
[BP] GO:0071704 |
organic substance metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, AURKB, AXL, BCL2, CBR1, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DHFR, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GSK3B, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, IDO1, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIM1, PPARA, PTGS2, PTPN1, PTPRS, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1, TYR, XDH |
7.97513 |
|
[BP] GO:0048583 |
regulation of response to stimulus
|
ABCB1, ADORA1, AKR1B1, ALOX15, AURKB, AXL, BCL2, CDK6, CSNK2A1, CYP19A1, CYP1B1, DHFR, DUSP3, EGFR, ESR1, ESR2, ESRRA, F10, F3, FABP4, FLT3, GPR35, GSK3B, HMGCR, HSPA1A, IDO1, IGF1R, INSR, KDR, MET, MMP12, MMP2, MMP9, NUAK1, PPARA, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
7.92044 |
|
[BP] GO:0048518 |
positive regulation of biological process
|
ABCB1, ACHE, ADORA1, AKR1B1, ALOX15, AURKB, AXL, BCL2, CA2, CA7, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DHFR, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, GPR35, GSK3B, HMGCR, HSPA1A, IDO1, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, PIM1, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
7.90517 |
|
[BP] GO:0060548 |
negative regulation of cell death
|
ADORA1, AKR1B1, AURKB, AXL, BCL2, CSNK2A1, EGFR, GSK3B, HMGCR, HSPA1A, IDO1, IGF1R, KDR, MET, MMP9, PIM1, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK |
7.87056 |
|
[BP] GO:0048584 |
positive regulation of response to stimulus
|
ADORA1, AKR1B1, ALOX15, AXL, BCL2, CSNK2A1, CYP1B1, EGFR, ESRRA, F10, F3, FABP4, FLT3, GPR35, GSK3B, HMGCR, HSPA1A, IDO1, INSR, KDR, MET, MMP12, MMP2, MMP9, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
7.78947 |
|
[BP] GO:0043069 |
negative regulation of programmed cell death
|
ADORA1, AKR1B1, AURKB, AXL, BCL2, CSNK2A1, EGFR, GSK3B, HMGCR, HSPA1A, IDO1, IGF1R, KDR, MET, MMP9, PIM1, PTGS2, PTPN1, SMAD3, SRC, TEK |
7.75374 |
|
[BP] GO:0009719 |
response to endogenous stimulus
|
AKR1B1, ALPL, BCL2, CA2, CA9, CSNK2A1, CYP1A2, EGFR, ESR1, ESRRA, FABP3, FLT3, GSK3B, HSD11B2, IGF1R, INSR, MMP2, PPARA, PTGS2, SMAD3, SRC, TEK |
7.633 |
|
[BP] GO:0019369 |
arachidonic acid metabolic process
|
ALOX15, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, PTGS2 |
7.5248 |
|
[BP] GO:0006796 |
phosphate-containing compound metabolic process
|
ACHE, ALOX15, ALPL, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DHFR, DUSP3, EGFR, FLT3, GSK3B, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIM1, PTGS2, PTPN1, PTPRS, SRC, TEK, TNKS, TOP1, XDH |
7.5248 |
|
[BP] GO:0032502 |
developmental process
|
ACHE, ADORA1, AKR1B1, ALOX15, ALPL, AURKB, AXL, BCL2, CA2, CA9, CBR1, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DHFR, DUSP3, EGFR, ESR1, ESRRA, ESRRB, FABP4, FLT3, FUT7, GBA2, GSK3B, HMGCR, HSD11B1, HSD17B2, INSR, KDR, MET, MMP2, MMP9, PIM1, PPARA, PTGS2, PTPRS, RORC, SMAD3, SRC, TEK, TNKS2, TYR |
7.48249 |
|
[BP] GO:0014070 |
response to organic cyclic compound
|
ALPL, BCL2, CA2, CA9, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DHFR, EGFR, ESR1, ESRRA, FLT3, HSD11B2, PTGS2, RORC, SRC, TEK, TYR |
7.41405 |
|
[BP] GO:0010646 |
regulation of cell communication
|
ACHE, ADORA1, AKR1B1, ALOX15, AURKB, AXL, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DUSP3, EGFR, ESR1, ESR2, F10, F3, FLT3, GPR35, GSK3B, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, NUAK1, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
7.35791 |
|
[BP] GO:0023051 |
regulation of signaling
|
ACHE, ADORA1, AKR1B1, ALOX15, AURKB, AXL, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DUSP3, EGFR, ESR1, ESR2, F10, F3, FLT3, GPR35, GSK3B, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, NUAK1, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
7.22576 |
|
[BP] GO:0009725 |
response to hormone
|
AKR1B1, ALPL, BCL2, CA2, CA9, CSNK2A1, CYP1A2, EGFR, ESR1, ESRRA, FABP3, FLT3, HSD11B2, INSR, PPARA, PTGS2, SRC, TEK |
7.22502 |
|
[BP] GO:0010941 |
regulation of cell death
|
ADORA1, AKR1B1, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, EGFR, ESR1, F3, FLT3, GSK3B, HMGCR, HSPA1A, IDO1, IGF1R, KDR, MET, MMP9, PIM1, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
7.20764 |
|
[BP] GO:0043067 |
regulation of programmed cell death
|
ADORA1, AKR1B1, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, EGFR, ESR1, F3, FLT3, GSK3B, HMGCR, HSPA1A, IDO1, IGF1R, KDR, MET, MMP9, PIM1, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
7.17576 |
|
[BP] GO:0043066 |
negative regulation of apoptotic process
|
ADORA1, AKR1B1, AURKB, AXL, BCL2, CSNK2A1, EGFR, GSK3B, HMGCR, HSPA1A, IDO1, IGF1R, KDR, MMP9, PIM1, PTGS2, PTPN1, SMAD3, SRC, TEK |
7.1718 |
|
[BP] GO:0006793 |
phosphorus metabolic process
|
ACHE, ALOX15, ALPL, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DHFR, DUSP3, EGFR, FLT3, GSK3B, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIM1, PTGS2, PTPN1, PTPRS, SRC, TEK, TNKS, TOP1, XDH |
7.1718 |
|
[BP] GO:0032501 |
multicellular organismal process
|
ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AXL, BCL2, CYP19A1, CYP1A2, CYP1B1, DUSP3, EGFR, ESR1, ESRRB, F10, F3, FABP4, HMGCR, HSD11B2, HSD17B2, IDO1, IGF1R, INSR, MET, MMP1, MMP12, MMP2, MMP9, PIM1, PPARA, PTGS2, RORC, SMAD3, SRC, TEK, TNKS2, TOP1, TYR |
7.1406 |
|
[BP] GO:0044255 |
cellular lipid metabolic process
|
ACHE, AKR1B10, ALOX15, ALOX5, CBR1, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, EGFR, FABP3, FABP4, FUT7, GBA2, HMGCR, MET, PPARA, PTGS2 |
7.11994 |
|
[BP] GO:0050896 |
response to stimulus
|
ABCB1, ACHE, ADORA1, ADORA3, AKR1B1, ALOX15, ALPL, AURKB, AXL, BCL2, CA2, CA6, CA9, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DHFR, EGFR, ESR1, ESRRA, F10, F3, FABP3, FABP4, FLT3, GSK3B, HMGCR, HSD11B2, HSD17B2, HSPA1A, IDO1, IGF1R, INSR, KDR, MMP12, MMP2, MMP9, NUAK1, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TOP1, TYR |
7.11549 |
|
[BP] GO:0048513 |
animal organ development
|
ACHE, AXL, BCL2, CA2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, EGFR, ESR1, ESRRA, ESRRB, FLT3, HSD11B1, HSD17B2, INSR, KDR, PPARA, PTPRS, SMAD3, SRC, TEK, TYR |
7.09825 |
|
[BP] GO:0033559 |
unsaturated fatty acid metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, PTGS2 |
7.08704 |
|
[BP] GO:1902533 |
positive regulation of intracellular signal transduction
|
ADORA1, AKR1B1, ALOX15, AXL, BCL2, CYP1B1, EGFR, F10, F3, FLT3, GPR35, HMGCR, HSPA1A, INSR, KDR, MET, PTGS2, PTPN1, SRC, TEK, XDH |
7.06567 |
|
[BP] GO:0042445 |
hormone metabolic process
|
ACHE, AKR1B1, CYP19A1, CYP1A1, CYP1B1, CYP3A4, ESR1, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
7.06567 |
|
[BP] GO:1902531 |
regulation of intracellular signal transduction
|
ADORA1, AKR1B1, ALOX15, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, DUSP3, EGFR, ESR1, F10, F3, FLT3, GPR35, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MMP9, NUAK1, PTGS2, PTPN1, SRC, TEK, XDH |
7.04258 |
|
[BP] GO:0006690 |
icosanoid metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, PTGS2 |
6.85821 |
|
[BP] GO:0048856 |
anatomical structure development
|
ACHE, ADORA1, AKR1B1, ALOX15, ALPL, AXL, BCL2, CA2, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DHFR, DUSP3, EGFR, ESR1, ESRRA, ESRRB, FLT3, GBA2, GSK3B, HSD11B1, HSD17B2, INSR, KDR, MMP9, PIM1, PPARA, PTGS2, PTPRS, RORC, SMAD3, SRC, TEK, TYR |
6.85821 |
|
[BP] GO:1901564 |
organonitrogen compound metabolic process
|
ACHE, AKR1B1, ALPL, AOX1, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP3A4, DHFR, DUSP3, EGFR, ESR1, F10, F3, FLT3, FUT7, GBA2, GSK3B, HMGCR, HSPA1A, IDO1, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIM1, PPARA, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1, TYR, XDH |
6.85821 |
|
[BP] GO:0046777 |
protein autophosphorylation
|
AURKB, CSNK2A1, EGFR, FLT3, GSK3B, IGF1R, INSR, KDR, PIM1, SRC, TEK |
6.84566 |
|
[BP] GO:0042981 |
regulation of apoptotic process
|
ADORA1, AKR1B1, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, EGFR, ESR1, F3, FLT3, GSK3B, HMGCR, HSPA1A, IDO1, IGF1R, KDR, MMP9, PIM1, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
6.65579 |
|
[BP] GO:0008284 |
positive regulation of cell proliferation
|
AKR1B1, BCL2, CDC25B, CDK6, CSNK2A1, EGFR, ESR1, F3, FLT3, HMGCR, IGF1R, INSR, KDR, MMP12, MMP2, MMP9, PIM1, PTGS2, TEK |
6.21086 |
|
[BP] GO:0009966 |
regulation of signal transduction
|
ADORA1, AKR1B1, ALOX15, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, DUSP3, EGFR, ESR1, ESR2, F10, F3, FLT3, GPR35, GSK3B, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, NUAK1, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
6.14174 |
|
[BP] GO:0070887 |
cellular response to chemical stimulus
|
AKR1B1, ALOX15, ALPL, AXL, BCL2, CDK6, CYP1A1, CYP1A2, CYP1B1, EGFR, ESR1, FABP4, FLT3, GSK3B, HSPA1A, IGF1R, INSR, KDR, MMP2, MMP9, PTGS2, RORC, SMAD3, SRC |
6.07832 |
|
[BP] GO:0048585 |
negative regulation of response to stimulus
|
ADORA1, ALOX15, BCL2, CDK6, CYP19A1, DUSP3, EGFR, ESR1, ESR2, GSK3B, HMGCR, HSPA1A, IGF1R, MET, MMP12, MMP9, PPARA, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TEK, XDH |
6.07821 |
|
[BP] GO:0032879 |
regulation of localization
|
ABCB1, ACHE, ADORA1, ADORA3, ALOX15, AXL, BCL2, CA2, CA7, CDK6, CSNK2A1, CYP19A1, CYP1B1, EGFR, F10, F3, GPR35, GSK3B, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK |
6.03408 |
|
[BP] GO:2000145 |
regulation of cell motility
|
ADORA1, ADORA3, BCL2, CDK6, CYP19A1, CYP1B1, EGFR, F10, F3, IGF1R, INSR, KDR, MET, MMP9, PTGS2, SMAD3, SRC, TEK |
5.91631 |
|
[BP] GO:0010035 |
response to inorganic substance
|
AKR1B1, ALOX15, AXL, BCL2, CA2, CYP1A1, CYP1A2, CYP1B1, EGFR, FABP4, KDR, MMP9, PTGS2, SRC |
5.87423 |
|
[BP] GO:0006468 |
protein phosphorylation
|
AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, EGFR, FLT3, GSK3B, IGF1R, INSR, KDR, MET, NUAK1, PIM1, SRC, TEK, TNKS, TOP1 |
5.86187 |
|
[BP] GO:0042446 |
hormone biosynthetic process
|
AKR1B1, CYP19A1, CYP3A4, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
5.8543 |
|
[BP] GO:0042493 |
response to drug
|
ABCB1, AKR1B1, AXL, BCL2, CA9, CDK6, CYP1A1, CYP1B1, DHFR, EGFR, FABP3, HMGCR, HSD11B2, KDR, PTGS2, SRC, TOP1 |
5.83865 |
|
[BP] GO:0001676 |
long-chain fatty acid metabolic process
|
ALOX15, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, PTGS2 |
5.7224 |
|
[BP] GO:0030334 |
regulation of cell migration
|
ADORA1, ADORA3, BCL2, CYP19A1, CYP1B1, EGFR, F10, F3, IGF1R, INSR, KDR, MET, MMP9, PTGS2, SMAD3, SRC, TEK |
5.5386 |
|
[BP] GO:0071310 |
cellular response to organic substance
|
AKR1B1, ALOX15, ALPL, AXL, BCL2, CDK6, CYP1A1, CYP1B1, EGFR, ESR1, FABP4, FLT3, GSK3B, IGF1R, INSR, KDR, MMP2, PTGS2, RORC, SMAD3, SRC |
5.53151 |
|
[BP] GO:0034754 |
cellular hormone metabolic process
|
AKR1B1, CYP19A1, CYP1A1, CYP1B1, CYP3A4, ESR1, HSD17B1, HSD17B2 |
5.47727 |
|
[BP] GO:1901568 |
fatty acid derivative metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, PTGS2 |
5.47727 |
|
[BP] GO:0048523 |
negative regulation of cellular process
|
ACHE, ADORA1, ADORA3, AKR1B1, AURKB, AXL, BCL2, CDK6, CSNK2A1, CYP19A1, CYP1B1, DHFR, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, GPR35, GSK3B, HMGCR, HSPA1A, IDO1, IGF1R, KDR, MET, MMP12, MMP9, PIM1, PPARA, PTGS2, PTPN1, PTPRS, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
5.46182 |
|
[BP] GO:0040012 |
regulation of locomotion
|
ADORA1, ADORA3, BCL2, CDK6, CYP19A1, CYP1B1, EGFR, F10, F3, IGF1R, INSR, KDR, MET, MMP9, PTGS2, SMAD3, SRC, TEK |
5.4534 |
|
[BP] GO:0051270 |
regulation of cellular component movement
|
ADORA1, ADORA3, BCL2, CDK6, CYP19A1, CYP1B1, EGFR, F10, F3, IGF1R, INSR, KDR, MET, MMP9, PTGS2, SMAD3, SRC, TEK |
5.43562 |
|
[BP] GO:0010817 |
regulation of hormone levels
|
ACHE, ADORA1, AKR1B1, CYP19A1, CYP1A1, CYP1B1, CYP3A4, EGFR, ESR1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
5.41234 |
|
[BP] GO:0019373 |
epoxygenase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6 |
5.35526 |
|
[BP] GO:0030335 |
positive regulation of cell migration
|
BCL2, EGFR, F10, F3, IGF1R, INSR, KDR, MET, MMP9, PTGS2, SMAD3, SRC, TEK |
5.22658 |
|
[BP] GO:0017144 |
drug metabolic process
|
ACHE, AKR1B1, AKR1B10, AOX1, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP3A4, DHFR, EGFR, HSPA1A, IDO1 |
5.22658 |
|
[BP] GO:0010648 |
negative regulation of cell communication
|
ACHE, ADORA1, BCL2, DUSP3, EGFR, ESR1, ESR2, GPR35, GSK3B, HMGCR, HSPA1A, IGF1R, MET, MMP12, MMP9, PTGS2, PTPN1, PTPRS, SMAD3, SRC, XDH |
5.18802 |
|
[BP] GO:0023057 |
negative regulation of signaling
|
ACHE, ADORA1, BCL2, DUSP3, EGFR, ESR1, ESR2, GPR35, GSK3B, HMGCR, HSPA1A, IGF1R, MET, MMP12, MMP9, PTGS2, PTPN1, PTPRS, SMAD3, SRC, XDH |
5.16904 |
|
[BP] GO:0006631 |
fatty acid metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, FABP3, PPARA, PTGS2 |
5.16183 |
|
[BP] GO:0009056 |
catabolic process
|
ACHE, ADORA1, AKR1B10, AOX1, AURKB, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP3A4, FABP3, FABP4, FUT7, GBA2, GSK3B, HSPA1A, IDO1, MMP1, MMP12, MMP2, MMP9, SRC, XDH |
5.10377 |
|
[BP] GO:2000147 |
positive regulation of cell motility
|
BCL2, EGFR, F10, F3, IGF1R, INSR, KDR, MET, MMP9, PTGS2, SMAD3, SRC, TEK |
5.07912 |
|
[BP] GO:0051173 |
positive regulation of nitrogen compound metabolic process
|
ADORA1, ALOX15, AURKB, BCL2, CDC25B, CSNK2A1, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GSK3B, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
5.02827 |
|
[BP] GO:0006694 |
steroid biosynthetic process
|
AKR1B1, CYP19A1, CYP3A4, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
5.02827 |
|
[BP] GO:0009611 |
response to wounding
|
ACHE, ADORA3, ALOX15, BCL2, CYP1A1, DHFR, EGFR, PPARA, SMAD3 |
5.01706 |
|
[BP] GO:0009893 |
positive regulation of metabolic process
|
ADORA1, ALOX15, AURKB, BCL2, CDC25B, CSNK2A1, DHFR, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FLT3, GSK3B, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
4.98234 |
|
[BP] GO:0051272 |
positive regulation of cellular component movement
|
BCL2, EGFR, F10, F3, IGF1R, INSR, KDR, MET, MMP9, PTGS2, SMAD3, SRC, TEK |
4.96911 |
|
[BP] GO:0051716 |
cellular response to stimulus
|
AKR1B1, ALOX15, ALPL, AURKB, AXL, BCL2, CA2, CA9, CDK6, CYP1A1, CYP1A2, CYP1B1, DHFR, EGFR, ESR1, FABP4, FLT3, GSK3B, HSPA1A, IGF1R, INSR, KDR, MMP2, MMP9, NUAK1, PTGS2, PTPN1, RORC, SMAD3, SRC |
4.95847 |
|
[BP] GO:0032844 |
regulation of homeostatic process
|
ADORA1, AURKB, BCL2, CA2, CA7, CDK6, EGFR, HMGCR, KDR, PTGS2, SRC, TNKS, TNKS2 |
4.93397 |
|
[BP] GO:0018108 |
peptidyl-tyrosine phosphorylation
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, SRC, TEK |
4.89911 |
|
[BP] GO:0032787 |
None
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, FABP3, GBA2, IDO1, PPARA, PTGS2 |
4.89911 |
|
[BP] GO:0018212 |
peptidyl-tyrosine modification
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, SRC, TEK |
4.84453 |
|
[BP] GO:0040017 |
positive regulation of locomotion
|
BCL2, EGFR, F10, F3, IGF1R, INSR, KDR, MET, MMP9, PTGS2, SMAD3, SRC, TEK |
4.81265 |
|
[BP] GO:0065009 |
regulation of molecular function
|
ABCB1, ADORA1, ADORA3, AURKB, BCL2, CDC25B, CSNK2A1, CYP1B1, DHFR, DUSP3, EGFR, ESR1, ESR2, F3, FABP4, FLT3, GPR35, GSK3B, HMGCR, HSPA1A, IGF1R, INSR, MET, MMP9, NUAK1, PIM1, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, XDH |
4.79218 |
|
[BP] GO:0032101 |
regulation of response to external stimulus
|
ADORA1, CYP19A1, EGFR, ESR1, F3, FABP4, HMGCR, IDO1, KDR, MET, MMP12, PPARA, PTGS2, PTPRS, SMAD3, TEK |
4.77803 |
|
[BP] GO:0048519 |
negative regulation of biological process
|
ACHE, ADORA1, ADORA3, AKR1B1, ALOX15, AURKB, AXL, BCL2, CDK6, CSNK2A1, CYP19A1, CYP1B1, DHFR, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, GPR35, GSK3B, HMGCR, HSPA1A, IDO1, IGF1R, KDR, MET, MMP12, MMP9, PIM1, PPARA, PTGS2, PTPN1, PTPRS, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
4.75842 |
|
[BP] GO:0031347 |
regulation of defense response
|
ADORA1, CYP19A1, EGFR, ESR1, FABP4, HSPA1A, IDO1, MMP12, MMP2, PPARA, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TEK |
4.75842 |
|
[BP] GO:0001666 |
response to hypoxia
|
ADORA1, BCL2, CYP1A1, HSD11B2, MMP2, PPARA, PTGS2, SMAD3, SRC, TEK |
4.75816 |
|
[BP] GO:1901615 |
organic hydroxy compound metabolic process
|
AKR1B1, AKR1B10, ALOX15, BCL2, CYP19A1, CYP1A1, CYP1B1, CYP3A4, DHFR, GBA2, HMGCR, TYR |
4.71623 |
|
[BP] GO:0031325 |
positive regulation of cellular metabolic process
|
ADORA1, ALOX15, AURKB, BCL2, CDC25B, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FLT3, GSK3B, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
4.71623 |
|
[BP] GO:0010604 |
positive regulation of macromolecule metabolic process
|
ADORA1, ALOX15, AURKB, BCL2, CDC25B, CSNK2A1, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GSK3B, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
4.669 |
|
[BP] GO:0036293 |
response to decreased oxygen levels
|
ADORA1, BCL2, CYP1A1, HSD11B2, MMP2, PPARA, PTGS2, SMAD3, SRC, TEK |
4.65199 |
|
[BP] GO:0016310 |
phosphorylation
|
AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, EGFR, FLT3, GSK3B, IGF1R, INSR, KDR, MET, NUAK1, PIM1, SRC, TEK, TNKS, TOP1 |
4.6289 |
|
[BP] GO:0044092 |
negative regulation of molecular function
|
ADORA3, AURKB, CSNK2A1, CYP1B1, DUSP3, ESR1, FABP4, GPR35, GSK3B, HMGCR, IGF1R, MET, MMP9, PIM1, PPARA, PTGS2, PTPN1, SRC, TNKS |
4.5574 |
|
[BP] GO:0010638 |
positive regulation of organelle organization
|
ALOX15, AURKB, BCL2, GSK3B, HSPA1A, INSR, KDR, MET, MMP9, SMAD3, SRC, TEK, TNKS, TNKS2 |
4.5433 |
|
[BP] GO:0050790 |
regulation of catalytic activity
|
ADORA1, ADORA3, AURKB, BCL2, CDC25B, CSNK2A1, DHFR, DUSP3, EGFR, ESR1, F3, FABP4, FLT3, GSK3B, HMGCR, HSPA1A, IGF1R, INSR, MMP9, NUAK1, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS, XDH |
4.50842 |
|
[BP] GO:0051896 |
regulation of protein kinase B signaling
|
AXL, EGFR, F10, F3, INSR, MET, SRC, TEK, XDH |
4.50673 |
|
[BP] GO:0051897 |
positive regulation of protein kinase B signaling
|
AXL, EGFR, F10, F3, INSR, MET, SRC, TEK |
4.50673 |
|
[BP] GO:0001952 |
regulation of cell-matrix adhesion
|
BCL2, CDK6, GSK3B, KDR, SMAD3, SRC, TEK |
4.48372 |
|
[BP] GO:0048511 |
rhythmic process
|
AXL, BCL2, CSNK2A1, EGFR, ESR1, GSK3B, PPARA, RORC, SRC, TOP1 |
4.43553 |
|
[BP] GO:0032847 |
regulation of cellular pH reduction
|
BCL2, CA2, CA7 |
4.39807 |
|
[BP] GO:0019220 |
regulation of phosphate metabolic process
|
ADORA1, ALOX15, BCL2, CDC25B, DUSP3, EGFR, ESRRB, FABP3, FABP4, FLT3, HMGCR, IGF1R, INSR, KDR, MMP9, NUAK1, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
4.38943 |
|
[BP] GO:0070482 |
response to oxygen levels
|
ADORA1, BCL2, CYP1A1, HSD11B2, MMP2, PPARA, PTGS2, SMAD3, SRC, TEK |
4.35018 |
|
[BP] GO:0051174 |
regulation of phosphorus metabolic process
|
ADORA1, ALOX15, BCL2, CDC25B, DUSP3, EGFR, ESRRB, FABP3, FABP4, FLT3, HMGCR, IGF1R, INSR, KDR, MMP9, NUAK1, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
4.33321 |
|
[BP] GO:0019752 |
carboxylic acid metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DHFR, FABP3, GBA2, IDO1, PIM1, PPARA, PTGS2, TYR |
4.31847 |
|
[BP] GO:0080135 |
regulation of cellular response to stress
|
CDK6, DHFR, DUSP3, EGFR, GSK3B, HMGCR, HSPA1A, IGF1R, MET, NUAK1, PTGS2, PTPN1, PTPRS, XDH |
4.30032 |
|
[BP] GO:0008610 |
lipid biosynthetic process
|
ACHE, AKR1B1, ALOX15, CSNK2A1, CYP19A1, CYP1A1, CYP3A4, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, PTGS2 |
4.29008 |
|
[BP] GO:0010562 |
positive regulation of phosphorus metabolic process
|
ADORA1, ALOX15, BCL2, CDC25B, EGFR, ESRRB, FABP3, FLT3, HMGCR, INSR, KDR, MMP9, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
4.27426 |
|
[BP] GO:0045937 |
positive regulation of phosphate metabolic process
|
ADORA1, ALOX15, BCL2, CDC25B, EGFR, ESRRB, FABP3, FLT3, HMGCR, INSR, KDR, MMP9, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
4.27426 |
|
[BP] GO:0051239 |
regulation of multicellular organismal process
|
ADORA1, ADORA3, AXL, BCL2, CA2, CDK6, CYP1B1, EGFR, ESR1, ESRRA, ESRRB, F3, GPR35, GSK3B, HMGCR, HSPA1A, IDO1, INSR, KDR, MET, MMP12, MMP9, PIM1, PTGS2, PTPRS, SMAD3, SRC, TEK, TNKS2, XDH |
4.27205 |
|
[BP] GO:0010243 |
response to organonitrogen compound
|
AKR1B1, DHFR, EGFR, FABP3, FLT3, GSK3B, HSD11B2, IGF1R, INSR, MMP2, PPARA, PTGS2, SRC, TEK, TYR |
4.25868 |
|
[BP] GO:0001503 |
ossification
|
ALOX15, ALPL, BCL2, EGFR, MMP2, MMP9, TEK |
4.22615 |
|
[BP] GO:0018193 |
peptidyl-amino acid modification
|
AURKB, AXL, BCL2, CSNK2A1, EGFR, F10, FLT3, GSK3B, IGF1R, INSR, KDR, MET, SRC, TEK, TNKS, TOP1 |
4.21454 |
|
[BP] GO:2000377 |
regulation of reactive oxygen species metabolic process
|
BCL2, CYP1B1, DHFR, EGFR, INSR, PTGS2, SMAD3, XDH |
4.20714 |
|
[BP] GO:0009628 |
response to abiotic stimulus
|
ADORA1, AKR1B1, AURKB, BCL2, CA2, CYP1A1, EGFR, HMGCR, HSD11B2, HSPA1A, MMP2, PPARA, PTGS2, SMAD3, SRC, TEK, TYR |
4.16097 |
|
[BP] GO:0030522 |
intracellular receptor signaling pathway
|
ESR1, ESR2, ESRRA, ESRRB, PIM1, PPARA, RORC, SRC |
4.10285 |
|
[BP] GO:0048661 |
positive regulation of smooth muscle cell proliferation
|
AKR1B1, EGFR, HMGCR, MMP2, MMP9, PTGS2 |
4.0443 |
|
[BP] GO:0006720 |
isoprenoid metabolic process
|
AKR1B10, CYP1A1, CYP1A2, CYP1B1, CYP3A4, EGFR, HMGCR |
3.97626 |
|
[BP] GO:0007169 |
transmembrane receptor protein tyrosine kinase signaling pathway
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, MMP2, MMP9, PTPN1, SRC, TEK |
3.96097 |
|
[BP] GO:0051130 |
positive regulation of cellular component organization
|
ALOX15, AURKB, AXL, BCL2, ESR1, GSK3B, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP9, SMAD3, SRC, TEK, TNKS, TNKS2 |
3.92406 |
|
[BP] GO:0010810 |
regulation of cell-substrate adhesion
|
ALOX15, BCL2, CDK6, GSK3B, KDR, SMAD3, SRC, TEK |
3.88334 |
|
[BP] GO:1901698 |
response to nitrogen compound
|
AKR1B1, DHFR, EGFR, FABP3, FLT3, GSK3B, HSD11B2, IGF1R, INSR, MMP2, PPARA, PTGS2, SRC, TEK, TYR |
3.87939 |
|
[BP] GO:0043401 |
steroid hormone mediated signaling pathway
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC, SRC |
3.87939 |
|
[BP] GO:0015711 |
organic anion transport
|
ABCB1, CA1, CA12, CA14, CA2, CA4, CA6, CA7, CA9, FABP3, PPARA |
3.87939 |
|
[BP] GO:0009968 |
negative regulation of signal transduction
|
BCL2, DUSP3, EGFR, ESR1, ESR2, GSK3B, HMGCR, HSPA1A, IGF1R, MET, MMP12, MMP9, PTGS2, PTPN1, PTPRS, SMAD3, SRC, XDH |
3.86804 |
|
[BP] GO:0001954 |
positive regulation of cell-matrix adhesion
|
CDK6, GSK3B, KDR, SMAD3, TEK |
3.86337 |
|
[BP] GO:1902532 |
negative regulation of intracellular signal transduction
|
BCL2, DUSP3, ESR1, HMGCR, HSPA1A, IGF1R, MET, MMP9, PTGS2, PTPN1, SRC, XDH |
3.82288 |
|
[BP] GO:0044093 |
positive regulation of molecular function
|
ABCB1, ADORA1, AURKB, BCL2, CDC25B, DHFR, EGFR, ESR1, ESR2, F3, FLT3, GSK3B, HSPA1A, INSR, MET, MMP9, PTPN1, SMAD3, SRC, TEK, TNKS, XDH |
3.82047 |
|
[BP] GO:0043436 |
oxoacid metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DHFR, FABP3, GBA2, IDO1, PIM1, PPARA, PTGS2, TYR |
3.81886 |
|
[BP] GO:0038083 |
peptidyl-tyrosine autophosphorylation
|
EGFR, IGF1R, INSR, KDR, SRC |
3.77976 |
|
[BP] GO:0051247 |
positive regulation of protein metabolic process
|
ADORA1, ALOX15, BCL2, CDC25B, CSNK2A1, EGFR, ESR1, F3, FLT3, GSK3B, HMGCR, HSPA1A, INSR, KDR, MMP9, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
3.74985 |
|
[BP] GO:0006082 |
organic acid metabolic process
|
ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, DHFR, FABP3, GBA2, IDO1, PIM1, PPARA, PTGS2, TYR |
3.7281 |
|
[BP] GO:1901652 |
response to peptide
|
AKR1B1, FABP3, GSK3B, HSD11B2, IGF1R, INSR, PPARA, PTGS2, SRC, TEK |
3.72601 |
|
[BP] GO:0016042 |
lipid catabolic process
|
ADORA1, AKR1B10, CYP19A1, CYP1A2, CYP1B1, CYP3A4, FABP3, FABP4, GBA2 |
3.72601 |
|
[BP] GO:0042325 |
regulation of phosphorylation
|
ADORA1, ALOX15, BCL2, CDC25B, DUSP3, EGFR, ESRRB, FABP4, FLT3, HMGCR, IGF1R, INSR, KDR, MMP9, PPARA, PTGS2, PTPN1, SRC, TEK, XDH |
3.64488 |
|
[BP] GO:1901701 |
cellular response to oxygen-containing compound
|
AKR1B1, AXL, CDK6, CYP1B1, EGFR, ESR1, GSK3B, IGF1R, INSR, MMP2, MMP9, PTGS2, RORC, SRC |
3.61733 |
|
[BP] GO:0042327 |
positive regulation of phosphorylation
|
ADORA1, ALOX15, BCL2, CDC25B, EGFR, ESRRB, FLT3, HMGCR, INSR, KDR, MMP9, PTGS2, PTPN1, SRC, TEK, XDH |
3.60413 |
|
[BP] GO:0019216 |
regulation of lipid metabolic process
|
ADORA1, CYP1A1, FABP3, FLT3, HMGCR, PPARA, PTGS2, RORC, SRC, TEK |
3.58693 |
|
[BP] GO:0009698 |
phenylpropanoid metabolic process
|
CYP1A1, CYP2A13, CYP2A6 |
3.57874 |
|
[BP] GO:0009804 |
coumarin metabolic process
|
CYP1A1, CYP2A13, CYP2A6 |
3.57874 |
|
[BP] GO:0008283 |
cell proliferation
|
ABCB1, ACHE, AURKB, BCL2, CYP1A1, EGFR, ESR1, FLT3, MET, PIM1, SRC, TEK, TYR |
3.56843 |
|
[BP] GO:0050793 |
regulation of developmental process
|
AXL, BCL2, CA2, CDK6, CYP1B1, EGFR, ESR1, ESRRA, ESRRB, F3, GSK3B, HMGCR, IDO1, INSR, KDR, NUAK1, PIM1, PPARA, PTGS2, PTPRS, RORC, SMAD3, SRC, TEK, TNKS2, XDH |
3.55277 |
|
[BP] GO:0071248 |
cellular response to metal ion
|
ALOX15, CYP1A1, CYP1A2, EGFR, FABP4, MMP9, PTGS2 |
3.55254 |
|
[BP] GO:0032270 |
positive regulation of cellular protein metabolic process
|
ADORA1, ALOX15, BCL2, CDC25B, EGFR, ESR1, F3, FLT3, GSK3B, HMGCR, HSPA1A, INSR, KDR, MMP9, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
3.54942 |
|
[BP] GO:2001243 |
negative regulation of intrinsic apoptotic signaling pathway
|
BCL2, HSPA1A, MMP9, PTGS2, PTPN1, SRC |
3.54769 |
|
[BP] GO:0008210 |
estrogen metabolic process
|
CYP19A1, CYP1B1, HSD17B1, HSD17B2 |
3.53699 |
|
[BP] GO:0010906 |
None
|
ESRRB, GSK3B, INSR, PPARA, RORC, SRC |
3.52555 |
|
[BP] GO:0048869 |
cellular developmental process
|
ACHE, ALPL, AXL, BCL2, CBR1, CDC25B, CDK6, CYP1A1, EGFR, ESR1, ESRRB, FABP4, FLT3, FUT7, GBA2, GSK3B, HMGCR, KDR, MET, MMP2, MMP9, PTGS2, PTPRS, RORC, SMAD3, SRC, TEK |
3.48074 |
|
[BP] GO:0030155 |
regulation of cell adhesion
|
ALOX15, BCL2, CDK6, CYP1B1, DUSP3, GSK3B, IDO1, KDR, NUAK1, PPARA, SMAD3, SRC, TEK |
3.48074 |
|
[BP] GO:0048545 |
response to steroid hormone
|
ALPL, BCL2, CA2, EGFR, FLT3, HSD11B2, PTGS2, SRC |
3.4639 |
|
[BP] GO:0007167 |
enzyme linked receptor protein signaling pathway
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, MMP2, MMP9, PTPN1, SMAD3, SRC, TEK |
3.44979 |
|
[BP] GO:0031960 |
response to corticosteroid
|
ALPL, BCL2, EGFR, FLT3, HSD11B2, PTGS2, SRC |
3.44127 |
|
[BP] GO:0051049 |
regulation of transport
|
ABCB1, ACHE, ADORA1, ALOX15, AXL, BCL2, CA2, CA7, CYP19A1, EGFR, GPR35, GSK3B, HMGCR, HSPA1A, INSR, MMP12, MMP9, PPARA, PTGS2, PTPN1, SMAD3, SRC |
3.43345 |
|
[BP] GO:0051701 |
interaction with host
|
AXL, EGFR, HSPA1A, INSR, MET, SMAD3, SRC |
3.39676 |
|
[BP] GO:0050727 |
regulation of inflammatory response
|
ADORA1, CYP19A1, EGFR, ESR1, FABP4, IDO1, PPARA, PTGS2, SMAD3, TEK |
3.38034 |
|
[BP] GO:1901617 |
organic hydroxy compound biosynthetic process
|
AKR1B1, ALOX15, CYP19A1, CYP3A4, DHFR, HMGCR, TYR |
3.34151 |
|
[BP] GO:0010811 |
positive regulation of cell-substrate adhesion
|
ALOX15, CDK6, GSK3B, KDR, SMAD3, TEK |
3.31716 |
|
[BP] GO:0006721 |
terpenoid metabolic process
|
AKR1B10, CYP1A1, CYP1A2, CYP1B1, CYP3A4, EGFR |
3.29752 |
|
[BP] GO:0009987 |
cellular process
|
ABCB1, ACHE, ADORA1, ADORA3, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, AURKB, AXL, BCL2, CA1, CA12, CA2, CA4, CA6, CA7, CA9, CBR1, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DHFR, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GPR35, GSK3B, HMGCR, HSD17B1, HSD17B2, HSPA1A, IDO1, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIM1, PPARA, PTGS2, PTPN1, PTPRS, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1, TUBB3, TYR, XDH |
3.28714 |
|
[BP] GO:0034614 |
cellular response to reactive oxygen species
|
AKR1B1, AXL, CYP1B1, EGFR, MMP9, SRC |
3.28007 |
|
[BP] GO:0009755 |
hormone-mediated signaling pathway
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC, SRC |
3.27235 |
|
[BP] GO:0003006 |
developmental process involved in reproduction
|
ALPL, AXL, BCL2, CDC25B, CYP19A1, EGFR, ESR1, ESRRB, HSD17B2, INSR, PTGS2, SRC |
3.26871 |
|
[BP] GO:0001934 |
positive regulation of protein phosphorylation
|
ADORA1, ALOX15, BCL2, CDC25B, EGFR, FLT3, HMGCR, INSR, KDR, MMP9, PTGS2, PTPN1, SRC, TEK, XDH |
3.24394 |
|
[BP] GO:0010038 |
response to metal ion
|
ALOX15, BCL2, CA2, CYP1A1, CYP1A2, EGFR, FABP4, MMP9, PTGS2 |
3.23321 |
|
[BP] GO:0043408 |
regulation of MAPK cascade
|
ADORA1, ALOX15, DUSP3, EGFR, FLT3, HMGCR, IGF1R, INSR, KDR, PTPN1, SRC, TEK, XDH |
3.20905 |
|
[BP] GO:0001101 |
response to acid chemical
|
AKR1B1, DHFR, EGFR, FABP3, HSD17B2, KDR, MMP2, PTGS2, SRC |
3.20424 |
|
[BP] GO:0071241 |
cellular response to inorganic substance
|
ALOX15, CYP1A1, CYP1A2, EGFR, FABP4, MMP9, PTGS2 |
3.20154 |
|
[BP] GO:0043410 |
positive regulation of MAPK cascade
|
ADORA1, ALOX15, EGFR, FLT3, HMGCR, INSR, KDR, PTPN1, SRC, TEK, XDH |
3.17425 |
|
[BP] GO:0000302 |
response to reactive oxygen species
|
AKR1B1, AXL, BCL2, CYP1B1, EGFR, MMP9, SRC |
3.17365 |
|
[BP] GO:0022414 |
reproductive process
|
AKR1B1, ALPL, AXL, BCL2, CDC25B, CYP19A1, CYP1A1, EGFR, ESR1, ESRRB, HSD11B2, HSD17B2, IDO1, INSR, MMP2, MMP9, PTGS2, SRC |
3.17365 |
|
[BP] GO:0006805 |
xenobiotic metabolic process
|
CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP3A4, RORC |
3.17113 |
|
[BP] GO:0019538 |
protein metabolic process
|
ACHE, ALPL, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DUSP3, EGFR, ESR1, F10, F3, FLT3, FUT7, GSK3B, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIM1, PPARA, PTPN1, PTPRS, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1 |
3.16948 |
|
[BP] GO:2001225 |
regulation of chloride transport
|
ABCB1, CA2, CA7 |
3.14806 |
|
[BP] GO:0097267 |
omega-hydroxylase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1 |
3.14806 |
|
[BP] GO:0001932 |
regulation of protein phosphorylation
|
ADORA1, ALOX15, BCL2, CDC25B, DUSP3, EGFR, FABP4, FLT3, HMGCR, IGF1R, INSR, KDR, MMP9, PTGS2, PTPN1, SRC, TEK, XDH |
3.08437 |
|
[BP] GO:0009892 |
negative regulation of metabolic process
|
ADORA1, AURKB, BCL2, CSNK2A1, DHFR, DUSP3, EGFR, ESR1, ESR2, ESRRA, FABP4, GSK3B, HMGCR, HSPA1A, IGF1R, KDR, MET, MMP12, MMP9, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TNKS, TNKS2, XDH |
3.08398 |
|
[BP] GO:0042180 |
None
|
AKR1B1, AKR1B10, CYP19A1, HMGCR, IDO1 |
3.07939 |
|
[BP] GO:0010907 |
None
|
ESRRB, INSR, PPARA, SRC |
3.05957 |
|
[BP] GO:0043405 |
regulation of MAP kinase activity
|
ADORA1, DUSP3, EGFR, FLT3, HMGCR, IGF1R, INSR, PTPN1, SRC |
3.04399 |
|
[BP] GO:0051240 |
positive regulation of multicellular organismal process
|
AXL, BCL2, CA2, CYP1B1, EGFR, ESRRB, F3, HMGCR, HSPA1A, IDO1, KDR, MET, MMP12, MMP9, PIM1, PTGS2, SMAD3, SRC, TEK |
3.04399 |
|
[BP] GO:0006807 |
nitrogen compound metabolic process
|
ACHE, AKR1B1, AKR1B10, ALPL, AOX1, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, DHFR, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FLT3, FUT7, GBA2, GSK3B, HMGCR, HSPA1A, IDO1, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIM1, PPARA, PTGS2, PTPN1, PTPRS, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1, TYR, XDH |
3.04399 |
|
[BP] GO:0010675 |
None
|
ESRRB, GSK3B, INSR, PPARA, RORC, SRC |
3.04399 |
|
[BP] GO:0009991 |
response to extracellular stimulus
|
ALPL, AXL, BCL2, CYP1A1, EGFR, HMGCR, HSD11B2, PTGS2, SRC, TYR |
3.04377 |
|
[BP] GO:0006979 |
response to oxidative stress
|
AKR1B1, AXL, BCL2, CYP1B1, EGFR, HSPA1A, MMP9, PTGS2, SRC |
3.02055 |
|
[BP] GO:0051098 |
regulation of binding
|
AURKB, BCL2, GSK3B, MET, MMP9, PPARA, SMAD3, SRC, TNKS |
3.02055 |
|
[BP] GO:0045834 |
positive regulation of lipid metabolic process
|
FABP3, FLT3, PPARA, PTGS2, SRC, TEK |
3.01018 |
|
[BP] GO:0007166 |
cell surface receptor signaling pathway
|
ADORA1, ADORA3, AXL, BCL2, CA1, CSNK2A1, EGFR, F3, FLT3, GPR35, GSK3B, IGF1R, INSR, KDR, MET, MMP2, MMP9, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2 |
2.99717 |
|
[BP] GO:0044283 |
None
|
AKR1B1, ALOX15, ALOX5, CYP19A1, CYP1A1, CYP3A4, DHFR, HMGCR, IDO1, PTGS2 |
2.9919 |
|
[BP] GO:1901575 |
None
|
ACHE, ADORA1, AKR1B10, AOX1, AURKB, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP3A4, FABP3, FABP4, FUT7, GBA2, GSK3B, HSPA1A, IDO1, XDH |
2.97757 |
|
[BP] GO:0010634 |
positive regulation of epithelial cell migration
|
KDR, MET, MMP9, PTGS2, SRC, TEK |
2.97699 |
|
[BP] GO:0006820 |
anion transport
|
ABCB1, CA1, CA12, CA14, CA2, CA4, CA6, CA7, CA9, FABP3, PPARA |
2.95648 |
|
[BP] GO:0071407 |
cellular response to organic cyclic compound
|
ALPL, CYP1A1, CYP1B1, EGFR, ESR1, FLT3, PTGS2, RORC, SRC |
2.9545 |
|
[BP] GO:0043085 |
positive regulation of catalytic activity
|
ADORA1, AURKB, BCL2, CDC25B, DHFR, EGFR, ESR1, F3, FLT3, GSK3B, HSPA1A, INSR, PTPN1, SMAD3, SRC, TEK, TNKS, XDH |
2.94005 |
|
[BP] GO:0051338 |
regulation of transferase activity
|
ADORA1, AURKB, CDC25B, DUSP3, EGFR, FABP4, FLT3, GSK3B, HMGCR, IGF1R, INSR, PTPN1, SRC, TEK, TNKS |
2.93904 |
|
[BP] GO:0048660 |
regulation of smooth muscle cell proliferation
|
AKR1B1, EGFR, HMGCR, MMP2, MMP9, PTGS2 |
2.92928 |
|
[BP] GO:0042738 |
exogenous drug catabolic process
|
CYP1A2, CYP2A6, CYP3A4 |
2.92928 |
|
[BP] GO:0007346 |
regulation of mitotic cell cycle
|
AURKB, BCL2, CDC25B, CDK6, CYP1A1, DUSP3, EGFR, HSPA1A, INSR, PIM1, SMAD3, TNKS |
2.92062 |
|
[BP] GO:0034599 |
cellular response to oxidative stress
|
AKR1B1, AXL, CYP1B1, EGFR, HSPA1A, MMP9, SRC |
2.91887 |
|
[BP] GO:0070372 |
regulation of ERK1 and ERK2 cascade
|
ALOX15, DUSP3, EGFR, HMGCR, KDR, PTPN1, SRC, TEK |
2.87506 |
|
[BP] GO:0009115 |
None
|
AOX1, XDH |
2.87227 |
|
[BP] GO:2000026 |
regulation of multicellular organismal development
|
AXL, BCL2, CA2, CDK6, CYP1B1, EGFR, ESR1, ESRRA, F3, GSK3B, HMGCR, IDO1, INSR, KDR, PIM1, PTGS2, PTPRS, SMAD3, SRC, TEK, XDH |
2.83894 |
|
[BP] GO:0006703 |
estrogen biosynthetic process
|
CYP19A1, HSD17B1, HSD17B2 |
2.8315 |
|
[BP] GO:0060255 |
regulation of macromolecule metabolic process
|
ACHE, ADORA1, ADORA3, ALOX15, AURKB, BCL2, CA9, CDC25B, CDK6, CSNK2A1, CYP1A2, CYP1B1, DHFR, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP4, FLT3, GSK3B, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, NUAK1, PIM1, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1, XDH |
2.8315 |
|
[BP] GO:0032103 |
positive regulation of response to external stimulus
|
EGFR, F3, FABP4, IDO1, KDR, MET, PTGS2, SMAD3 |
2.8315 |
|
[BP] GO:0002009 |
morphogenesis of an epithelium
|
BCL2, CA2, CA9, EGFR, ESR1, MET, SMAD3, SRC |
2.80441 |
|
[BP] GO:0035690 |
cellular response to drug
|
AKR1B1, AXL, CDK6, CYP1B1, EGFR, KDR, PTGS2, SRC |
2.80441 |
|
[BP] GO:0031099 |
regeneration
|
AXL, BCL2, CSNK2A1, DHFR, EGFR, FLT3 |
2.80441 |
|
[BP] GO:0043393 |
regulation of protein binding
|
AURKB, BCL2, GSK3B, MET, MMP9, PPARA, SRC |
2.78673 |
|
[BP] GO:0032268 |
regulation of cellular protein metabolic process
|
ADORA1, ALOX15, BCL2, CDC25B, CSNK2A1, DHFR, DUSP3, EGFR, ESR1, F3, FABP4, FLT3, GSK3B, HMGCR, HSPA1A, IGF1R, INSR, KDR, MMP9, NUAK1, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
2.78219 |
|
[BP] GO:0043281 |
regulation of cysteine-type endopeptidase activity involved in apoptotic process
|
CSNK2A1, F3, MMP9, PTGS2, SMAD3, SRC, XDH |
2.7773 |
|
[BP] GO:0033273 |
response to vitamin
|
ALPL, CYP1A1, EGFR, PTGS2, TYR |
2.7773 |
|
[BP] GO:0044267 |
cellular protein metabolic process
|
ALPL, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DUSP3, EGFR, ESR1, F10, FLT3, FUT7, GSK3B, IGF1R, INSR, KDR, MET, MMP1, MMP2, NUAK1, PIM1, PTPN1, PTPRS, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1 |
2.77625 |
|
[BP] GO:0031399 |
regulation of protein modification process
|
ADORA1, ALOX15, BCL2, CDC25B, DUSP3, EGFR, FABP4, FLT3, HMGCR, HSPA1A, IGF1R, INSR, KDR, MMP9, NUAK1, PTGS2, PTPN1, SRC, TEK, XDH |
2.77625 |
|
[BP] GO:0051384 |
response to glucocorticoid
|
ALPL, BCL2, EGFR, FLT3, HSD11B2, PTGS2 |
2.76311 |
|
[BP] GO:0060065 |
uterus development
|
CYP19A1, ESR1, SRC |
2.75289 |
|
[BP] GO:1904407 |
positive regulation of nitric oxide metabolic process
|
EGFR, INSR, PTGS2, SMAD3 |
2.75238 |
|
[BP] GO:0045429 |
positive regulation of nitric oxide biosynthetic process
|
EGFR, INSR, PTGS2, SMAD3 |
2.75238 |
|
[BP] GO:0019222 |
regulation of metabolic process
|
ACHE, ADORA1, ADORA3, ALOX15, AURKB, BCL2, CA9, CDC25B, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DHFR, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GSK3B, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, NUAK1, PIM1, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1, XDH |
2.70379 |
|
[BP] GO:0051054 |
positive regulation of DNA metabolic process
|
AURKB, EGFR, IGF1R, INSR, SRC, TNKS, TNKS2 |
2.70139 |
|
[BP] GO:0032845 |
None
|
ADORA1, BCL2, HMGCR, SRC, TNKS, TNKS2 |
2.68844 |
|
[BP] GO:0006950 |
response to stress
|
ACHE, ADORA1, ADORA3, AKR1B1, ALOX15, AXL, BCL2, CA2, CA9, CYP1A1, CYP1A2, CYP1B1, DHFR, EGFR, GSK3B, HSD11B2, HSPA1A, IDO1, MMP2, MMP9, NUAK1, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK |
2.68274 |
|
[BP] GO:0044089 |
positive regulation of cellular component biogenesis
|
ALOX15, ESR1, GSK3B, HSPA1A, KDR, MET, MMP1, SMAD3, SRC, TEK |
2.67969 |
|
[BP] GO:1903727 |
positive regulation of phospholipid metabolic process
|
FABP3, FLT3, SRC, TEK |
2.67964 |
|
[BP] GO:0042592 |
homeostatic process
|
ADORA1, AKR1B1, AXL, BCL2, CA12, CA2, CA7, EGFR, ESR1, FABP3, FABP4, FLT3, GPR35, INSR, MET, SMAD3, SRC |
2.66415 |
|
[BP] GO:0051050 |
positive regulation of transport
|
ABCB1, ACHE, ADORA1, AXL, BCL2, CA2, CYP19A1, EGFR, GSK3B, INSR, MMP12, PTGS2, SMAD3, SRC |
2.61833 |
|
[BP] GO:2000379 |
positive regulation of reactive oxygen species metabolic process
|
EGFR, INSR, PTGS2, SMAD3, XDH |
2.61276 |
|
[BP] GO:0030540 |
female genitalia development
|
AXL, CYP19A1, ESR1 |
2.5935 |
|
[BP] GO:0019372 |
lipoxygenase pathway
|
ALOX15, ALOX5, PTGS2 |
2.5935 |
|
[BP] GO:0043065 |
positive regulation of apoptotic process
|
BCL2, CYP1B1, F3, GSK3B, HMGCR, IDO1, MMP9, PTGS2, SMAD3, SRC, XDH |
2.5935 |
|
[BP] GO:0002682 |
regulation of immune system process
|
ADORA1, ALOX15, AXL, BCL2, CA2, CDK6, CYP19A1, DUSP3, ESR1, ESRRA, HSPA1A, IDO1, MMP12, MMP2, PTPN1, PTPRS, SMAD3, SRC |
2.59099 |
|
[BP] GO:0006464 |
cellular protein modification process
|
ALPL, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DUSP3, EGFR, ESR1, F10, FLT3, FUT7, GSK3B, IGF1R, INSR, KDR, MET, NUAK1, PIM1, PTPN1, PTPRS, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1 |
2.58334 |
|
[BP] GO:0036211 |
protein modification process
|
ALPL, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DUSP3, EGFR, ESR1, F10, FLT3, FUT7, GSK3B, IGF1R, INSR, KDR, MET, NUAK1, PIM1, PTPN1, PTPRS, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1 |
2.58334 |
|
[BP] GO:0031334 |
positive regulation of protein complex assembly
|
ALOX15, ESR1, GSK3B, HSPA1A, MET, MMP1, SRC |
2.57409 |
|
[BP] GO:0051128 |
regulation of cellular component organization
|
ALOX15, AURKB, AXL, BCL2, CSNK2A1, EGFR, ESR1, ESR2, GSK3B, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP9, PTPN1, PTPRS, SMAD3, SRC, TEK, TNKS, TNKS2 |
2.57398 |
|
[BP] GO:0009636 |
response to toxic substance
|
AKR1B1, ALPL, AXL, BCL2, CYP1A1, CYP1B1, HMGCR, KDR, SRC |
2.57258 |
|
[BP] GO:0044248 |
cellular catabolic process
|
ACHE, AKR1B10, AOX1, AURKB, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP3A4, FABP3, FABP4, GBA2, GSK3B, HSPA1A, IDO1, SRC, XDH |
2.56956 |
|
[BP] GO:0032846 |
positive regulation of homeostatic process
|
AURKB, CA2, CA7, EGFR, PTGS2, TNKS, TNKS2 |
2.56745 |
|
[BP] GO:0043068 |
positive regulation of programmed cell death
|
BCL2, CYP1B1, F3, GSK3B, HMGCR, IDO1, MMP9, PTGS2, SMAD3, SRC, XDH |
2.5674 |
|
[BP] GO:0031667 |
response to nutrient levels
|
ALPL, BCL2, CYP1A1, EGFR, HMGCR, HSD11B2, PTGS2, SRC, TYR |
2.55307 |
|
[BP] GO:0002683 |
negative regulation of immune system process
|
ADORA1, ALOX15, AXL, CDK6, CYP19A1, DUSP3, IDO1, MMP12, PTPRS |
2.54614 |
|
[BP] GO:0003018 |
None
|
ADORA1, EGFR, HMGCR, PTGS2, SRC, TEK |
2.54309 |
|
[BP] GO:1904355 |
positive regulation of telomere capping
|
AURKB, TNKS, TNKS2 |
2.53075 |
|
[BP] GO:0031324 |
negative regulation of cellular metabolic process
|
AURKB, BCL2, CSNK2A1, DHFR, DUSP3, ESR1, ESR2, ESRRA, FABP4, GSK3B, HMGCR, HSPA1A, IGF1R, MET, MMP12, MMP9, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TNKS, TNKS2, XDH |
2.53075 |
|
[BP] GO:2001242 |
regulation of intrinsic apoptotic signaling pathway
|
BCL2, HSPA1A, MMP9, PTGS2, PTPN1, SRC |
2.50335 |
|
[BP] GO:0010605 |
negative regulation of macromolecule metabolic process
|
AURKB, CSNK2A1, DHFR, DUSP3, EGFR, ESR1, ESR2, ESRRA, FABP4, GSK3B, HMGCR, HSPA1A, IGF1R, KDR, MMP12, MMP9, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TNKS, TNKS2, XDH |
2.48271 |
|
[BP] GO:0046110 |
None
|
AOX1, XDH |
2.48271 |
|
[BP] GO:0032849 |
positive regulation of cellular pH reduction
|
CA2, CA7 |
2.48271 |
|
[BP] GO:0006367 |
transcription initiation from RNA polymerase II promoter
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC |
2.48222 |
|
[BP] GO:2000116 |
regulation of cysteine-type endopeptidase activity
|
CSNK2A1, F3, MMP9, PTGS2, SMAD3, SRC, XDH |
2.47128 |
|
[BP] GO:0016137 |
None
|
AKR1B1, AKR1B10, GBA2 |
2.46957 |
|
[BP] GO:0022900 |
electron transport chain
|
AKR1B1, AOX1, CYP19A1, CYP1A2, IDO1, XDH |
2.45609 |
|
[BP] GO:0051828 |
entry into other organism involved in symbiotic interaction
|
AXL, EGFR, HSPA1A, MET, SRC |
2.41992 |
|
[BP] GO:0051806 |
entry into cell of other organism involved in symbiotic interaction
|
AXL, EGFR, HSPA1A, MET, SRC |
2.41992 |
|
[BP] GO:0030260 |
entry into host cell
|
AXL, EGFR, HSPA1A, MET, SRC |
2.41992 |
|
[BP] GO:0044409 |
entry into host
|
AXL, EGFR, HSPA1A, MET, SRC |
2.41992 |
|
[BP] GO:0018105 |
peptidyl-serine phosphorylation
|
AURKB, BCL2, GSK3B, SRC, TNKS, TOP1 |
2.41955 |
|
[BP] GO:0048732 |
gland development
|
BCL2, CSNK2A1, CYP19A1, EGFR, INSR, SMAD3, TYR |
2.4142 |
|
[BP] GO:1903428 |
positive regulation of reactive oxygen species biosynthetic process
|
EGFR, INSR, PTGS2, SMAD3 |
2.41223 |
|
[BP] GO:0010676 |
None
|
ESRRB, INSR, PPARA, SRC |
2.41223 |
|
[BP] GO:0050678 |
None
|
CDK6, EGFR, F3, KDR, MMP12, SMAD3, TEK, XDH |
2.4121 |
|
[BP] GO:0051900 |
regulation of mitochondrial depolarization
|
BCL2, KDR, SRC |
2.41173 |
|
[BP] GO:0072593 |
reactive oxygen species metabolic process
|
BCL2, CYP1A1, CYP1A2, CYP1B1, EGFR |
2.40843 |
|
[BP] GO:0032210 |
regulation of telomere maintenance via telomerase
|
AURKB, SRC, TNKS, TNKS2 |
2.38458 |
|
[BP] GO:0051726 |
regulation of cell cycle
|
AURKB, BCL2, CDC25B, CDK6, CSNK2A1, CYP1A1, DUSP3, EGFR, HSPA1A, INSR, PIM1, PTGS2, SMAD3, SRC, TNKS |
2.36424 |
|
[BP] GO:0051893 |
regulation of focal adhesion assembly
|
KDR, SMAD3, SRC, TEK |
2.35627 |
|
[BP] GO:0090109 |
regulation of cell-substrate junction assembly
|
KDR, SMAD3, SRC, TEK |
2.35627 |
|
[BP] GO:0031348 |
negative regulation of defense response
|
ADORA1, CYP19A1, MMP12, PPARA, SMAD3, TEK |
2.34867 |
|
[BP] GO:0010942 |
positive regulation of cell death
|
BCL2, CYP1B1, F3, GSK3B, HMGCR, IDO1, MMP9, PTGS2, SMAD3, SRC, XDH |
2.32179 |
|
[BP] GO:0006109 |
regulation of carbohydrate metabolic process
|
ESRRB, GSK3B, INSR, PPARA, RORC, SRC |
2.30937 |
|
[BP] GO:0042542 |
response to hydrogen peroxide
|
AKR1B1, AXL, BCL2, CYP1B1, SRC |
2.30141 |
|
[BP] GO:0009894 |
regulation of catabolic process
|
ADORA1, BCL2, CSNK2A1, EGFR, ESRRB, GSK3B, HSPA1A, INSR, KDR, MET, PPARA, PTPN1, SMAD3 |
2.29509 |
|
[BP] GO:0071498 |
cellular response to fluid shear stress
|
CA2, PTGS2, SRC |
2.29288 |
|
[BP] GO:0001505 |
regulation of neurotransmitter levels
|
ACHE, CYP1B1, DHFR, EGFR, INSR, PTGS2, SMAD3 |
2.29288 |
|
[BP] GO:1903391 |
regulation of adherens junction organization
|
KDR, SMAD3, SRC, TEK |
2.27607 |
|
[BP] GO:0045428 |
regulation of nitric oxide biosynthetic process
|
EGFR, INSR, PTGS2, SMAD3 |
2.27607 |
|
[BP] GO:0051246 |
regulation of protein metabolic process
|
ADORA1, ALOX15, BCL2, CDC25B, CSNK2A1, DHFR, DUSP3, EGFR, ESR1, F3, FABP4, FLT3, GSK3B, HMGCR, HSPA1A, IGF1R, INSR, KDR, MMP9, NUAK1, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
2.24068 |
|
[BP] GO:0030520 |
intracellular estrogen receptor signaling pathway
|
ESR1, ESR2, SRC |
2.23544 |
|
[BP] GO:1901361 |
None
|
AOX1, CYP19A1, CYP1A1, CYP1A2, CYP2A6, CYP3A4, HSPA1A, IDO1, XDH |
2.23311 |
|
[BP] GO:0009891 |
positive regulation of biosynthetic process
|
AURKB, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, IGF1R, INSR, KDR, MET, MMP12, PPARA, PTGS2, RORC, SMAD3, SRC, TNKS, TNKS2 |
2.23311 |
|
[BP] GO:0070213 |
None
|
TNKS, TNKS2 |
2.23311 |
|
[BP] GO:0006145 |
None
|
AOX1, XDH |
2.23311 |
|
[BP] GO:0018894 |
dibenzo-p-dioxin metabolic process
|
CYP1A1, CYP1A2 |
2.23311 |
|
[BP] GO:0034502 |
protein localization to chromosome
|
AURKB, ESR1, TNKS, TNKS2 |
2.23159 |
|
[BP] GO:0048729 |
tissue morphogenesis
|
BCL2, CA2, CA9, EGFR, ESR1, MET, SMAD3, SRC |
2.22675 |
|
[BP] GO:0031401 |
positive regulation of protein modification process
|
ADORA1, ALOX15, BCL2, CDC25B, EGFR, FLT3, HMGCR, INSR, KDR, MMP9, PTGS2, PTPN1, SRC, TEK, XDH |
2.22373 |
|
[BP] GO:0071495 |
cellular response to endogenous stimulus
|
AKR1B1, EGFR, ESR1, FLT3, GSK3B, IGF1R, INSR, MMP2, PTGS2, SMAD3, SRC |
2.22224 |
|
[BP] GO:1904356 |
regulation of telomere maintenance via telomere lengthening
|
AURKB, SRC, TNKS, TNKS2 |
2.20766 |
|
[BP] GO:0018209 |
peptidyl-serine modification
|
AURKB, BCL2, GSK3B, SRC, TNKS, TOP1 |
2.20328 |
|
[BP] GO:0050728 |
negative regulation of inflammatory response
|
ADORA1, CYP19A1, PPARA, SMAD3, TEK |
2.19969 |
|
[BP] GO:0009404 |
toxin metabolic process
|
CYP1A1, CYP1A2, CYP1B1 |
2.19612 |
|
[BP] GO:0048878 |
chemical homeostasis
|
AKR1B1, BCL2, CA12, CA2, CA7, EGFR, ESR1, FABP3, FABP4, GPR35, INSR, MET, SMAD3 |
2.18324 |
|
[BP] GO:0048608 |
reproductive structure development
|
AXL, BCL2, CYP19A1, ESR1, HSD17B2, INSR, SRC |
2.16674 |
|
[BP] GO:0051894 |
None
|
KDR, SMAD3, TEK |
2.14628 |
|
[BP] GO:1903409 |
reactive oxygen species biosynthetic process
|
CYP1A1, CYP1A2, CYP1B1 |
2.14628 |
|
[BP] GO:0051172 |
None
|
AURKB, CSNK2A1, DHFR, DUSP3, EGFR, ESR1, ESR2, ESRRA, FABP4, HMGCR, HSPA1A, IGF1R, MMP12, MMP9, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TNKS, TNKS2, XDH |
2.13358 |
|
[BP] GO:0008285 |
negative regulation of cell proliferation
|
ADORA1, ADORA3, BCL2, CDK6, CYP1B1, FABP3, HSPA1A, IDO1, PTGS2, SMAD3, XDH |
2.12696 |
|
[BP] GO:0051704 |
multi-organism process
|
AXL, BCL2, CDK6, CYP1A1, EGFR, HSD11B2, HSPA1A, IDO1, INSR, KDR, MET, MMP1, MMP12, SMAD3, SRC, TOP1 |
2.12258 |
|
[BP] GO:2000573 |
positive regulation of DNA biosynthetic process
|
AURKB, SRC, TNKS, TNKS2 |
2.11522 |
|
[BP] GO:0050806 |
positive regulation of synaptic transmission
|
ADORA1, CA2, CA7, EGFR, PTGS2 |
2.11265 |
|
[BP] GO:0006766 |
vitamin metabolic process
|
AOX1, CBR1, CYP1A1, CYP3A4, DHFR |
2.11265 |
|
[BP] GO:0032496 |
response to lipopolysaccharide
|
ALPL, AXL, CYP1A1, CYP1A2, IDO1, PTGS2, SRC |
2.1115 |
|
[BP] GO:0007584 |
response to nutrient
|
ALPL, CYP1A1, EGFR, HMGCR, PTGS2, TYR |
2.1102 |
|
[BP] GO:0050927 |
None
|
F3, KDR, SMAD3 |
2.10599 |
|
[BP] GO:0043434 |
None
|
FABP3, HSD11B2, INSR, PPARA, PTGS2, SRC, TEK |
2.10599 |
|
[BP] GO:0080090 |
regulation of primary metabolic process
|
ADORA1, ADORA3, ALOX15, AURKB, BCL2, CA9, CDC25B, CSNK2A1, CYP1A1, CYP1B1, DHFR, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GSK3B, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, NUAK1, PIM1, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
2.10599 |
|
[BP] GO:0051171 |
regulation of nitrogen compound metabolic process
|
ADORA1, ADORA3, ALOX15, AURKB, BCL2, CA9, CDC25B, CSNK2A1, CYP1B1, DHFR, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GSK3B, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, NUAK1, PIM1, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
2.10563 |
|
[BP] GO:0030574 |
collagen catabolic process
|
MMP1, MMP12, MMP2, MMP9 |
2.09993 |
|
[BP] GO:0032102 |
negative regulation of response to external stimulus
|
ADORA1, CYP19A1, HMGCR, PPARA, PTPRS, SMAD3, TEK |
2.09993 |
|
[BP] GO:0043412 |
macromolecule modification
|
ALPL, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DUSP3, EGFR, ESR1, F10, FLT3, FUT7, GSK3B, IGF1R, INSR, KDR, MET, NUAK1, PIM1, PTPN1, PTPRS, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1 |
2.0975 |
|
[BP] GO:0009605 |
response to external stimulus
|
ADORA1, ALPL, AXL, BCL2, CDK6, CYP1A1, CYP1A2, EGFR, HMGCR, HSD11B2, IDO1, MMP12, PTGS2, SMAD3, SRC, TYR |
2.08621 |
|
[BP] GO:0032355 |
response to estradiol
|
CYP1A2, EGFR, ESR1, ESRRA, PTGS2 |
2.07696 |
|
[BP] GO:0070374 |
positive regulation of ERK1 and ERK2 cascade
|
ALOX15, EGFR, HMGCR, KDR, SRC, TEK |
2.07502 |
|
[BP] GO:0009607 |
response to biotic stimulus
|
ALPL, AXL, BCL2, CDK6, CYP1A1, CYP1A2, GSK3B, IDO1, MMP12, PTGS2, SMAD3, SRC |
2.07502 |
|
[BP] GO:0031323 |
regulation of cellular metabolic process
|
ACHE, ADORA1, ADORA3, ALOX15, AURKB, BCL2, CA9, CDC25B, CSNK2A1, CYP1B1, DHFR, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GSK3B, HMGCR, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, NUAK1, PIM1, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
2.07396 |
|
[BP] GO:0006706 |
steroid catabolic process
|
CYP19A1, CYP1A2, CYP3A4 |
2.07396 |
|
[BP] GO:0050926 |
None
|
F3, KDR, SMAD3 |
2.07396 |
|
[BP] GO:0005979 |
None
|
ESRRB, GSK3B, INSR |
2.07396 |
|
[BP] GO:1904353 |
regulation of telomere capping
|
AURKB, TNKS, TNKS2 |
2.07396 |
|
[BP] GO:1903393 |
None
|
KDR, SMAD3, TEK |
2.07396 |
|
[BP] GO:0010962 |
None
|
ESRRB, GSK3B, INSR |
2.07396 |
|
[BP] GO:0043696 |
None
|
CDK6, ESRRB |
2.07274 |
|
[BP] GO:0043697 |
None
|
CDK6, ESRRB |
2.07274 |
|
[BP] GO:0010641 |
None
|
F3, SRC |
2.07274 |
|
[BP] GO:0007598 |
None
|
F10, F3 |
2.07274 |
|
[BP] GO:2001233 |
regulation of apoptotic signaling pathway
|
BCL2, GSK3B, HSPA1A, MMP9, PTGS2, PTPN1, SMAD3, SRC |
2.07274 |
|
[BP] GO:0065007 |
biological regulation
|
ABCB1, ACHE, ADORA1, ADORA3, AKR1B1, ALOX15, AURKB, AXL, BCL2, CA1, CA12, CA2, CA7, CA9, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, DHFR, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, GPR35, GSK3B, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, IDO1, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIM1, PPARA, PTGS2, PTPN1, PTPRS, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1, XDH |
2.07274 |
|
[BP] GO:0051094 |
positive regulation of developmental process
|
AXL, BCL2, CA2, CYP1B1, ESRRB, F3, HMGCR, IDO1, INSR, KDR, PIM1, PTGS2, SMAD3, SRC, TEK |
2.07114 |
|
[BP] GO:0045935 |
positive regulation of nucleobase-containing compound metabolic process
|
AURKB, EGFR, ESR1, ESR2, ESRRA, ESRRB, HSPA1A, IGF1R, INSR, MET, MMP12, PPARA, PTPN1, RORC, SMAD3, SRC, TNKS, TNKS2 |
2.06916 |
|
[BP] GO:0043549 |
regulation of kinase activity
|
ADORA1, CDC25B, DUSP3, EGFR, FABP4, FLT3, HMGCR, IGF1R, INSR, PTPN1, SRC, TEK |
2.06738 |
|
[BP] GO:0045913 |
None
|
ESRRB, INSR, PPARA, SRC |
2.05338 |
|
[BP] GO:1904357 |
None
|
SRC, TNKS, TNKS2 |
2.03857 |
|
[BP] GO:0006352 |
DNA-templated transcription, initiation
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC |
2.00801 |
|
[BP] GO:0003013 |
None
|
ADORA1, EGFR, HMGCR, PTGS2, SRC, TEK |
2.00801 |
|
[CC] GO:0044432 |
endoplasmic reticulum part
|
BCL2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, EGFR, F10, FLT3, GBA2, HMGCR, HSD11B1, HSD11B2, HSD17B2, PTGS2, PTPN1 |
3.41469 |
|
[CC] GO:0005789 |
endoplasmic reticulum membrane
|
BCL2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, EGFR, GBA2, HMGCR, HSD11B1, HSD11B2, HSD17B2, PTGS2 |
3.36956 |
|
[CC] GO:0044444 |
cytoplasmic part
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, AOX1, AURKB, BCL2, CA1, CA2, CA4, CA7, CBR1, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DHFR, DUSP3, EGFR, ESR1, ESR2, F10, FABP3, FABP4, FLT3, FUT7, GBA2, GSK3B, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, IDO1, INSR, KDR, MMP2, MMP9, PIM1, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TNKS, TNKS2, TOP1, TYR, XDH |
2.97244 |
|
[CC] GO:0043227 |
membrane-bounded organelle
|
ABCB1, ACHE, ADORA1, AKR1B1, AKR1B10, ALPL, AOX1, AURKB, AXL, BCL2, CA1, CA2, CA4, CA6, CBR1, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, DHFR, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GSK3B, HMGCR, HSPA1A, IGF1R, INSR, KDR, MMP12, MMP2, MMP9, NUAK1, PIM1, PPARA, PTGS2, PTPN1, PTPRS, RORC, SMAD3, SRC, TNKS, TNKS2, TOP1, TUBB3, TYR, XDH |
2.75885 |
|
[CC] GO:0016020 |
membrane
|
ABCB1, ACHE, ADORA1, ADORA3, ALOX15, ALOX5, ALPL, AXL, BCL2, CA12, CA14, CA2, CA4, CA9, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, EGFR, ESR1, F10, F3, FLT3, FUT7, GBA2, GPR35, GSK3B, HMGCR, HSD11B1, HSD11B2, HSD17B2, IGF1R, INSR, KDR, MET, MMP2, PIM1, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TEK, TNKS, TNKS2, TYR |
2.52649 |
|
[CC] GO:0043226 |
organelle
|
ABCB1, ACHE, ADORA1, AKR1B1, AKR1B10, ALOX15, ALPL, AOX1, AURKB, AXL, BCL2, CA1, CA2, CA4, CA6, CA9, CBR1, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP3A4, DHFR, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GSK3B, HMGCR, HSPA1A, IDO1, IGF1R, INSR, KDR, MMP12, MMP2, MMP9, NUAK1, PIM1, PPARA, PTGS2, PTPN1, PTPRS, RORC, SMAD3, SRC, TNKS, TNKS2, TOP1, TUBB3, TYR, XDH |
2.45575 |
|
[CC] GO:0031233 |
None
|
CA4, F10, F3 |
2.34998 |
|
[CC] GO:0016323 |
basolateral plasma membrane
|
ADORA1, CA2, CA4, CA9, EGFR, TEK |
2.18215 |
|
[MF] GO:0003824 |
catalytic activity
|
ABCB1, ACHE, ADORA1, AKR1B1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, AURKB, AXL, CA1, CA12, CA14, CA2, CA4, CA6, CA7, CA9, CBR1, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DHFR, DUSP3, EGFR, F10, F3, FLT3, FUT7, GBA2, GSK3B, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, IDO1, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIM1, PTGS2, PTPN1, PTPRS, SRC, TEK, TNKS, TNKS2, TOP1, TUBB3, TYR, XDH |
18.2909 |
|
[MF] GO:0046914 |
transition metal ion binding
|
ALOX15, ALOX5, AOX1, CA1, CA12, CA2, CA4, CA6, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, ESR1, ESR2, ESRRA, ESRRB, MMP1, MMP12, MMP2, MMP9, PIM1, PPARA, PTPN1, RORC, SMAD3, TNKS, TYR, XDH |
16.4194 |
|
[MF] GO:0043167 |
ion binding
|
ABCB1, ACHE, ALOX15, ALOX5, ALPL, AOX1, AURKB, AXL, CA1, CA12, CA14, CA2, CA4, CA6, CA7, CA9, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DHFR, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, GSK3B, HMGCR, HSD17B1, HSPA1A, IDO1, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIM1, PPARA, PTGS2, PTPN1, PTPRS, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1, TUBB3, TYR, XDH |
15.7608 |
|
[MF] GO:0004089 |
carbonate dehydratase activity
|
CA1, CA12, CA14, CA2, CA4, CA6, CA7, CA9 |
11.8272 |
|
[MF] GO:0016491 |
oxidoreductase activity
|
AKR1B1, AKR1B10, ALOX15, ALOX5, AOX1, CBR1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DHFR, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, IDO1, PTGS2, TYR, XDH |
10.7099 |
|
[MF] GO:0016712 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4 |
8.10516 |
|
[MF] GO:0005506 |
iron ion binding
|
ALOX15, ALOX5, AOX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, XDH |
7.5248 |
|
[MF] GO:0016836 |
hydro-lyase activity
|
CA1, CA12, CA14, CA2, CA4, CA6, CA7, CA9 |
7.4879 |
|
[MF] GO:0008270 |
zinc ion binding
|
CA1, CA12, CA2, CA4, CA6, CA7, CA9, ESR1, ESR2, ESRRA, ESRRB, MMP1, MMP12, MMP2, MMP9, PPARA, PTPN1, RORC, SMAD3, TNKS |
7.47672 |
|
[MF] GO:0048037 |
cofactor binding
|
AOX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DHFR, HMGCR, HSD11B2, HSD17B1, IDO1, PTGS2, SRC, XDH |
7.32921 |
|
[MF] GO:0020037 |
heme binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, IDO1, PTGS2, SRC |
7.25656 |
|
[MF] GO:0004714 |
transmembrane receptor protein tyrosine kinase activity
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, TEK |
7.1718 |
|
[MF] GO:0016614 |
oxidoreductase activity, acting on CH-OH group of donors
|
AKR1B1, AKR1B10, AOX1, CBR1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2, XDH |
7.09825 |
|
[MF] GO:0046906 |
tetrapyrrole binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, IDO1, PTGS2, SRC |
7.06567 |
|
[MF] GO:0070330 |
aromatase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP3A4 |
6.88814 |
|
[MF] GO:0008144 |
drug binding
|
ABCB1, ACHE, AURKB, AXL, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP3A4, DHFR, EGFR, FLT3, GSK3B, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIM1, PPARA, SRC, TEK, TOP1 |
6.85739 |
|
[MF] GO:0016835 |
carbon-oxygen lyase activity
|
CA1, CA12, CA14, CA2, CA4, CA6, CA7, CA9 |
6.63376 |
|
[MF] GO:0043169 |
cation binding
|
ACHE, ALOX15, ALOX5, ALPL, AOX1, AURKB, CA1, CA12, CA14, CA2, CA4, CA6, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, ESR1, ESR2, ESRRA, ESRRB, F10, IDO1, MMP1, MMP12, MMP2, MMP9, NUAK1, PIM1, PPARA, PTGS2, PTPN1, RORC, SMAD3, TNKS, TNKS2, TYR, XDH |
6.49055 |
|
[MF] GO:0019199 |
transmembrane receptor protein kinase activity
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, TEK |
6.46255 |
|
[MF] GO:0046872 |
metal ion binding
|
ALOX15, ALOX5, ALPL, AOX1, AURKB, CA1, CA12, CA14, CA2, CA4, CA6, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, ESR1, ESR2, ESRRA, ESRRB, F10, IDO1, MMP1, MMP12, MMP2, MMP9, NUAK1, PIM1, PPARA, PTGS2, PTPN1, RORC, SMAD3, TNKS, TNKS2, TYR, XDH |
6.20274 |
|
[MF] GO:0005496 |
steroid binding
|
CYP3A4, ESR1, ESR2, ESRRA, ESRRB, HSD11B2, HSD17B1, RORC |
6.18216 |
|
[MF] GO:0004497 |
monooxygenase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, TYR |
5.87423 |
|
[MF] GO:0004672 |
protein kinase activity
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, GSK3B, IGF1R, INSR, KDR, MET, NUAK1, PIM1, SRC, TEK, TOP1 |
5.72358 |
|
[MF] GO:0016705 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, PTGS2, TYR |
5.47727 |
|
[MF] GO:0019825 |
oxygen binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP3A4 |
5.21558 |
|
[MF] GO:0016616 |
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
|
AKR1B1, AKR1B10, CBR1, HMGCR, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
5.19019 |
|
[MF] GO:0098531 |
transcription factor activity, direct ligand regulated sequence-specific DNA binding
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC |
5.02827 |
|
[MF] GO:0004879 |
nuclear receptor activity
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC |
5.02827 |
|
[MF] GO:0004713 |
protein tyrosine kinase activity
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, SRC, TEK |
4.98234 |
|
[MF] GO:0008289 |
lipid binding
|
ALOX15, AXL, CYP3A4, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, HSD11B2, HSD17B1, PPARA, RORC |
4.81066 |
|
[MF] GO:0016773 |
phosphotransferase activity, alcohol group as acceptor
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, GSK3B, IGF1R, INSR, KDR, MET, NUAK1, PIM1, SRC, TEK, TOP1 |
4.77402 |
|
[MF] GO:0043168 |
anion binding
|
ABCB1, ALOX15, AOX1, AURKB, AXL, CDK6, CSNK2A1, DHFR, EGFR, F10, F3, FABP3, FABP4, FLT3, GSK3B, HMGCR, HSD17B1, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIM1, PTPRS, SRC, TEK, TOP1, TUBB3, XDH |
4.67854 |
|
[MF] GO:0003707 |
steroid hormone receptor activity
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC |
4.62063 |
|
[MF] GO:0036094 |
small molecule binding
|
ABCB1, ADORA1, AOX1, AURKB, AXL, CDK6, CSNK2A1, DHFR, EGFR, FABP3, FABP4, FLT3, GSK3B, HMGCR, HSD11B2, HSD17B1, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIM1, SRC, TEK, TOP1, TUBB3, XDH |
4.58446 |
|
[MF] GO:0008395 |
steroid hydroxylase activity
|
CYP19A1, CYP1A1, CYP2A13, CYP2A6, CYP3A4 |
4.40742 |
|
[MF] GO:0016301 |
kinase activity
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, GSK3B, IGF1R, INSR, KDR, MET, NUAK1, PIM1, SRC, TEK, TOP1 |
4.32908 |
|
[MF] GO:0000166 |
nucleotide binding
|
ABCB1, AOX1, AURKB, AXL, CDK6, CSNK2A1, DHFR, EGFR, FLT3, GSK3B, HMGCR, HSD11B2, HSD17B1, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIM1, SRC, TEK, TOP1, TUBB3, XDH |
4.15559 |
|
[MF] GO:1901265 |
nucleoside phosphate binding
|
ABCB1, AOX1, AURKB, AXL, CDK6, CSNK2A1, DHFR, EGFR, FLT3, GSK3B, HMGCR, HSD11B2, HSD17B1, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIM1, SRC, TEK, TOP1, TUBB3, XDH |
4.1544 |
|
[MF] GO:0016829 |
lyase activity
|
CA1, CA12, CA14, CA2, CA4, CA6, CA7, CA9 |
3.94858 |
|
[MF] GO:0140096 |
catalytic activity, acting on a protein
|
AURKB, AXL, CDC25B, CDK6, CSNK2A1, DUSP3, EGFR, F10, F3, FLT3, GSK3B, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIM1, PTPN1, PTPRS, SRC, TEK, TOP1 |
3.81122 |
|
[MF] GO:0044877 |
macromolecular complex binding
|
ACHE, ADORA1, CSNK2A1, EGFR, ESRRB, FLT3, IGF1R, INSR, KDR, MMP12, MMP9, PIM1, PPARA, PTPN1, SMAD3, SRC |
3.61314 |
|
[MF] GO:0016772 |
transferase activity, transferring phosphorus-containing groups
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, GSK3B, IGF1R, INSR, KDR, MET, NUAK1, PIM1, SRC, TEK, TOP1 |
3.50611 |
|
[MF] GO:0016702 |
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
|
ALOX15, ALOX5, IDO1, PTGS2 |
3.41324 |
|
[MF] GO:0032403 |
protein complex binding
|
ACHE, ADORA1, EGFR, ESRRB, FLT3, IGF1R, INSR, KDR, MMP12, MMP9, PPARA, PTPN1, SMAD3, SRC |
3.40612 |
|
[MF] GO:0019899 |
enzyme binding
|
AURKB, BCL2, CDC25B, CYP1A1, CYP1A2, CYP2A6, CYP3A4, DUSP3, EGFR, ESR1, ESR2, ESRRB, F3, GSK3B, HMGCR, HSPA1A, MET, PPARA, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS2 |
3.38341 |
|
[MF] GO:1901363 |
heterocyclic compound binding
|
ABCB1, ADORA1, AOX1, AURKB, AXL, BCL2, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DHFR, EGFR, ESR1, ESR2, ESRRA, ESRRB, FLT3, GSK3B, HMGCR, HSD11B2, HSD17B1, HSPA1A, IDO1, IGF1R, INSR, KDR, MET, MMP12, NUAK1, PIM1, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TOP1, TUBB3, XDH |
3.38314 |
|
[MF] GO:0033764 |
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
|
HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
3.36166 |
|
[MF] GO:0016701 |
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen
|
ALOX15, ALOX5, IDO1, PTGS2 |
3.36166 |
|
[MF] GO:0097159 |
organic cyclic compound binding
|
ABCB1, ADORA1, AOX1, AURKB, AXL, BCL2, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP3A4, DHFR, EGFR, ESR1, ESR2, ESRRA, ESRRB, FLT3, GSK3B, HMGCR, HSD11B2, HSD17B1, HSPA1A, IDO1, IGF1R, INSR, KDR, MET, MMP12, NUAK1, PIM1, PPARA, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TOP1, TUBB3, XDH |
3.34151 |
|
[MF] GO:0019902 |
phosphatase binding
|
BCL2, EGFR, HMGCR, MET, PPARA, PTPN1, SMAD3 |
3.31038 |
|
[MF] GO:0009055 |
electron transfer activity
|
AKR1B1, AOX1, CYP19A1, CYP1A2, IDO1, XDH |
3.28007 |
|
[MF] GO:0016725 |
oxidoreductase activity, acting on CH or CH2 groups
|
CYP1A2, CYP3A4, XDH |
3.27329 |
|
[MF] GO:0004716 |
signal transducer, downstream of receptor, with protein tyrosine kinase activity
|
EGFR, INSR, KDR |
3.27329 |
|
[MF] GO:0016229 |
steroid dehydrogenase activity
|
HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
3.2588 |
|
[MF] GO:0038023 |
signaling receptor activity
|
ADORA1, ADORA3, AXL, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, IGF1R, INSR, KDR, MET, PPARA, RORC, TEK |
3.1085 |
|
[MF] GO:0038052 |
RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
|
ESR1, ESR2 |
2.87227 |
|
[MF] GO:0003845 |
None
|
HSD11B1, HSD11B2 |
2.87227 |
|
[MF] GO:0008389 |
None
|
CYP2A13, CYP2A6 |
2.87227 |
|
[MF] GO:0060089 |
molecular transducer activity
|
ADORA1, ADORA3, AXL, CDK6, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, IGF1R, INSR, KDR, MET, PPARA, RORC, TEK |
2.82828 |
|
[MF] GO:0005524 |
ATP binding
|
ABCB1, AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, GSK3B, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIM1, SRC, TEK, TOP1 |
2.77001 |
|
[MF] GO:0042562 |
hormone binding
|
ACHE, EGFR, HSD17B1, IGF1R, INSR |
2.71523 |
|
[MF] GO:0032559 |
adenyl ribonucleotide binding
|
ABCB1, AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, GSK3B, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIM1, SRC, TEK, TOP1 |
2.65513 |
|
[MF] GO:0016903 |
None
|
AKR1B1, AKR1B10, AOX1, XDH |
2.64399 |
|
[MF] GO:0030554 |
adenyl nucleotide binding
|
ABCB1, AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, GSK3B, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIM1, SRC, TEK, TOP1 |
2.62003 |
|
[MF] GO:0004872 |
receptor activity
|
ADORA1, ADORA3, AXL, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, IGF1R, INSR, KDR, MET, PPARA, RORC, TEK |
2.52649 |
|
[MF] GO:0004871 |
signal transducer activity
|
ADORA1, ADORA3, AXL, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, IGF1R, INSR, KDR, MET, PPARA, RORC, SMAD3, TEK |
2.50098 |
|
[MF] GO:0050473 |
arachidonate 15-lipoxygenase activity
|
ALOX15, PTGS2 |
2.48271 |
|
[MF] GO:0070576 |
vitamin D 24-hydroxylase activity
|
CYP1A1, CYP3A4 |
2.48271 |
|
[MF] GO:0034056 |
estrogen response element binding
|
ESR1, ESR2 |
2.23311 |
|
[MF] GO:0034875 |
caffeine oxidase activity
|
CYP1A2, CYP3A4 |
2.23311 |
|
[MF] GO:0033695 |
oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor
|
CYP1A2, CYP3A4 |
2.23311 |
|
[MF] GO:0035639 |
purine ribonucleoside triphosphate binding
|
ABCB1, AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, GSK3B, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIM1, SRC, TEK, TOP1, TUBB3 |
2.23311 |
|
[MF] GO:0019903 |
protein phosphatase binding
|
BCL2, EGFR, HMGCR, MET, PTPN1 |
2.15268 |
|
[MF] GO:0005518 |
collagen binding
|
ACHE, MMP12, MMP9, SMAD3 |
2.13627 |
|
[MF] GO:0032555 |
purine ribonucleotide binding
|
ABCB1, AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, GSK3B, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIM1, SRC, TEK, TOP1, TUBB3 |
2.12 |
|
[MF] GO:0017076 |
purine nucleotide binding
|
ABCB1, AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, GSK3B, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIM1, SRC, TEK, TOP1, TUBB3 |
2.0975 |
|
[MF] GO:0032553 |
ribonucleotide binding
|
ABCB1, AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, GSK3B, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIM1, SRC, TEK, TOP1, TUBB3 |
2.08943 |
|
[MF] GO:0017171 |
serine hydrolase activity
|
ACHE, F10, F3, MMP1, MMP12, MMP2, MMP9 |
2.07396 |
|
[MF] GO:0101020 |
estrogen 16-alpha-hydroxylase activity
|
CYP1A1, CYP3A4 |
2.07274 |
|
[MF] GO:0030284 |
estrogen receptor activity
|
ESR1, ESR2 |
2.07274 |
|
[MF] GO:0043559 |
insulin binding
|
IGF1R, INSR |
2.07274 |
|
[MF] GO:0019838 |
growth factor binding
|
EGFR, IGF1R, INSR, KDR, TEK |
2.00801 |
