TCM-ID Component

Description of the Component

Component ID	TCMH1652
Latin Name	Paris polyphylla
English Name	rhizome of verticillate paris
Chinese Pinyin Name	Qi Ye Yi Zhi Hua
中文名	ä¸ƒå¶ä¸€æžèŠ±
TCM Properties	Cold,Bitter
TCM Meridians	Liver
Therapeutic Class English	Heat clearence
Therapeutic Class Chinese	æ¸…çƒ
Functions	remove heat, counteract toxicity, cause the subsidence of swelling and alleviate pain, and relieve convulsions
Toxicity	Toxic
Geo-authentic habitats (道地产区)	NA
Reference	Chinese Pharmacopoeia (2015)
Barcode ID	ITSAH2421-14
Barcode Source	BOLDSYSTEMS

TCM Prescriptions with the Component

Prescription ID	Prescription English Name	Prescription Chinese Name
TCMFx2129	Compound Powder of Snake-bile and Fritillary Bulb	å¤æ–¹è›‡èƒ†å·è´æ•£
TCMFx4649	Ji De Sheng She Yao Tablets	å£å¾·èƒœè›‡è¯ç‰‡
TCMFx4862	Luo Fu Shan Bai Cao You	ç½—æµ®å±±ç™¾è‰æ²¹
TCMF2373	QG Yin Qiao Powder	ç¾Œè†é“¶ç¿˜æ±¤
TCMF2108	Qi Protection Double Solution Decoction
TCMFx2150	Tumor Removing Decoction	æ¶ˆç˜¿æ±¤

Targeted Human Proteins by the Ingredient of Component

Target ID	Gene Symbol	Target Name	Target Class	Uniprot ID
TCMT132	BCHE	Butyrylcholinesterase	Hydrolase	P06276
TCMT215	CYP1A1	Cytochrome P450 1A1	Oxidoreductase	P04798
TCMT219	CYP1A2	Cytochrome P450 1A2	Oxidoreductase	P05177
TCMT232	ABCB1	P-glycoprotein 1	Transporter	P08183
TCMT240	AMY1A	Salivary alpha-amylase	Unclassified	P04745
TCMT257	CYP1B1	Cytochrome P450 1B1	Oxidoreductase	Q16678
TCMT63	PPARA	Peroxisome proliferator-activated receptor alpha	Nuclear receptor	Q07869
TCMT64	PPARD	Peroxisome proliferator-activated receptor delta	Nuclear receptor	Q03181
TCMT67	PPARG	Peroxisome proliferator-activated receptor gamma	Nuclear receptor	P37231

Targeted Pathogenic Microbes by the Ingredient of Component

Target ID	Target Name
TCMT1218	Staphylococcus aureus
TCMT1229	Enterococcus faecalis
TCMT1232	Pseudomonas aeruginosa
TCMT1246	Escherichia coli

Ingredient Structrues

Ingredient ID: TCMC348
Formula: C27H44O7

Common Name	20-Hydroxyecdysone
IUPAC Name	(2S,3R,5R,9R,10R,13R,14S,17S)-2,3,14-trihydroxy-10,13-dimethyl-17-[(2R,3R)-2,3,6-trihydroxy-6-methylheptan-2-yl]-2,3,4,5,9,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-6-one
Canonical SMILES	O[C@H]1C[C@@]2(C)[C@@H](C[C@H]1O)C(=O)C=C1[C@@H]2CC[C@]2([C@@]1(O)CC[C@@H]2[C@]([C@@H](CCC(O)(C)C)O)(O)C)C
Standard InCHI	InChI=1S/C27H44O7/c1-23(2,32)9-8-22(31)26(5,33)21-7-11-27(34)16-12-18(28)17-13-19(29)20(30)14-24(17,3)15(16)6-10-25(21,27)4/h12,15,17,19-22,29-34H,6-11,13-14H2,1-5H3/t15-,17-,19+,20-,21-,22+,24+,25+,26+,27+/m0/s1
Standard InCHIKey	NKDFYOWSKOHCCO-YPVLXUMRSA-N
External Identifiers	ChEMBL [CHEMBL224128]; PubChem [5459840];
Reference of Component-Ingredient Pair	29126784

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH1673	Gentiana macrophylla	Qin Jiao	ç§¦è‰½
TCMH1508	Commiphora myrrha	Mo Yao	æ²¡è¯
TCMH1496	Rhizoma dryopteris crassirhizomae	Mian Ma Guan Zhong	ç»µé©¬è´¯ä¼—
TCMH281	Dipsacus asper	Chuan Duan	å·æ–
TCMH1674	Gentiana straminea	Qin Jiao Hua	ç§¦è‰½èŠ±
TCMH255	Vigna angularis	Chi Dou	èµ¤è±†
TCMH1102	Tinospora capillipes	Jin Guo Lan	é‡‘æžœæ¦„
TCMH202	Bombyx mori	Can Yong	èš•è›¹
TCMH1588	Achyranthes bidentata	Niu Xi	ç‰›è†
TCMH1331	Rhaponticum uniflorum	Lou Lu	æ¼èŠ¦
TCMH1584	Achyranthes bidentata	Niu Teng	ç‰›è—¤
TCMH75	Bombyx mori	Bai Jiang Can	ç™½åƒµèš•
TCMH197	Bombyx mori	Can E	èš•è›¾
TCMH200	Bombyx mori	Can Jian	èš•èŒ§
TCMH201	Bombyx mori	Can Sha	èš•ç ‚
TCMH1652	Paris polyphylla	Qi Ye Yi Zhi Hua	ä¸ƒå¶ä¸€æžèŠ±
TCMH1507	Commiphora myrrha	Mo Xiang	æ²¡é¦™
TCMH2595	Rhododendron micranthum	Zhao Shan Bai	ç…§å±±ç™½
TCMH2576	Paris polyphylla	Zao Xiu	èš¤ä¼‘
TCMH2646	Rhizoma paridis	Chong Lou	é‡æ¥¼
TCMH2362	Artemisia lactiflora	Ya Jiao Ai	é¸è„šè‰¾
TCMH2017	Artemisia lactiflora	Si Ji Cai	å››å£èœ

Ingredient ID: TCMC1064
Formula: C16H12O6

Common Name	Diosmetin
IUPAC Name	5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)chromen-4-one
Canonical SMILES	COc1ccc(cc1O)c1cc(=O)c2c(o1)cc(cc2O)O
Standard InCHI	InChI=1S/C16H12O6/c1-21-13-3-2-8(4-10(13)18)14-7-12(20)16-11(19)5-9(17)6-15(16)22-14/h2-7,17-19H,1H3
Standard InCHIKey	MBNGWHIJMBWFHU-UHFFFAOYSA-N
External Identifiers	ChEMBL [CHEMBL90568]; PubChem [5281612];
Reference of Component-Ingredient Pair	22860452

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH888	Pithecellobium clypearia	Hou Er Huan Jin Gao	çŒ´è€³çŽ¯æµ¸è†
TCMH1144	Schizonepetae herba	Jing Jie Tan	è†èŠ¥ç‚
TCMH370	Herba cirsii japonici	Da Ji(1)	å¤§è“Ÿ
TCMH733	Desmodium styracifolium	Guang Jin Qian Cao	å¹¿é‡‘é’±è‰
TCMH463	Sanguisorba officinalis	Di Yu Tan	åœ°æ¦†ç‚
TCMH1460	Zanthoxylum nitidum	Mao Liang Mian Zhen	æ¯›ä¸¤é¢é’ˆ
TCMH1141	Schizonepeta tenuifolia	Jing Jie	è†èŠ¥
TCMH226	Camellia sinensis	Cha Ye	èŒ¶å¶
TCMH1872	Cnidium monnieri	She Ma Zi	è›‡éº»å
TCMH261	Ericerus pela	Chong Bai La	è™«ç™½èœ¡
TCMH1601	Nelumbo nucifera	Ou Pian	è—•ç‰‡
TCMH1503	Eclipta prostrata	Mo Han Lian	å¢¨æ—±èŽ²
TCMH710	Trichosanthes kirilowii maxim	Gua Lou Zi	ç“œè’Œå
TCMH348	Lobelia chinensis	Da Ban Bian Lian	å¤§åŠè¾¹èŽ²
TCMH122	Lobelia chinensis	Ban Bian Lian	åŠè¾¹èŽ²
TCMH1866	Cnidium monnieri	She Chuang Zi	è›‡åºŠå
TCMH705	Trichosanthes kirilowii	Gua Lou	ç“œè’Œ
TCMH706	Trichosanthes kirilowii	Gua Lou Pi	ç“œè’Œçš®
TCMH707	Trichosanthes kirilowii	Gua Lou Ren	ç“œè’Œä»
TCMH708	Trichosanthes kirilowii	Gua Lou Ren Shuang	ç“œè’Œä»éœœ
TCMH709	Trichosanthes kirilowii	Gua Lou Shi	æ è’Œå®ž
TCMH711	Trichosanthes kirilowii	Gua Lou Gen	æ æ¥¼æ ¹
TCMH712	Trichosanthes kirilowii	Gua Lou Ren(1)	æ æ¥¼ä»
TCMH368	Herba cirsii japonici	Da Ji Gen	å¤§è“Ÿæ ¹
TCMH369	Herba cirsii japonici	Da Ji Gen Jin Gao	å¤§è“Ÿæ ¹æµ¸è†
TCMH462	Sanguisorba officinalis	Di Yu	åœ°æ¦†
TCMH60	Ginkgo biloba	Bai Guo	ç™½æžœ
TCMH61	Ginkgo biloba	Bai Guo Ren	ç™½æžœä»
TCMH1652	Paris polyphylla	Qi Ye Yi Zhi Hua	ä¸ƒå¶ä¸€æžèŠ±
TCMH814	Nelumbo nucifera	He Geng	è·æ¢—
TCMH825	Nelumbo nucifera	He Ye	è·å¶
TCMH1275	Nelumbo nucifera	Lian Zi	èŽ²å
TCMH1276	Nelumbo nucifera	Lian Zi Xin	èŽ²åå¿ƒ
TCMH1598	Nelumbo nucifera	Ou	è—•
TCMH1599	Nelumbo nucifera	Ou Fen	è—•ç²‰
TCMH51	Camellia sinensis	Bai Cha	ç™½èŒ¶
TCMH886	Pithecellobium clypearia	Hou Er Huan	çŒ´è€³çŽ¯
TCMH887	Pithecellobium clypearia	Hou Er Huan Gan Jin Gao	çŒ´è€³çŽ¯å¹²æµ¸è†
TCMH1856	Gardenia jasminoides	Shan Zhi	å±±æ €
TCMH2506	Ginkgo biloba	Yin Xing Ye	é“¶æå¶
TCMH2372	Bergenia purpurascens	Yan Bai Cai	å²©ç™½èœ
TCMH2576	Paris polyphylla	Zao Xiu	èš¤ä¼‘
TCMH2642	Gardenia jasminoides	Zhi Zi Jin Gao	æ €åæµ¸è†
TCMH2086	Trichosanthes kirilowii	Tian Hua Fen	å¤©èŠ±ç²‰
TCMH2297	Cirsium setosum	Xiao Ji	å°è“Ÿ
TCMH2452	Chrysanthemum indicum	Ye Ju Hua	é‡ŽèŠèŠ±
TCMH2593	Octopus vulgaris	Zhang Yu	ç« é±¼
TCMH2641	Gardenia jasminoides	Zhi Zi	æ €å

Properties

Ingredient ID	Formulae	Name	MW	AlogP	MlogP	XlogP	# HBA	# HBD	PSA	# Rotatable Bond	# Ring	# Heacy Atom	Lipinski RO5 Violation
TCMC348	C27H44O7	20-Hydroxyecdysone	480.31	-1.1982	3.66	1.049	7	6	138.45	16	4	34	1
TCMC1064	C16H12O6	Diosmetin	300.06	-1.9363	2.56	1.123	1	3	96.22	6	3	22	0

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Data Section	Select to Download
1. General Information of the Component
2. TCM Prescriptions with the Component
3. Putative Targets
4. Activity & References for Filtering Putative Targets
5. Ingredient Data & Chemical Structure Information (Properties, InChI, InChIkey, SMILES, etc.)

Component: Paris polyphylla ä¸ƒå¶ä¸€æžèŠ±

Description of the Component

Component ID

Latin Name

English Name

Chinese Pinyin Name

中文名

TCM Properties

TCM Meridians

Therapeutic Class English

Therapeutic Class Chinese

Functions

Toxicity

Geo-authentic habitats (道地产区)

Reference

Barcode ID

Barcode Source

TCM Prescriptions with the Component

Targeted Human Proteins by the Ingredient of Component

Targeted Pathogenic Microbes by the Ingredient of Component

Ingredient Structrues

Ingredient ID: TCMC348

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC1064

Occurrence of the ingredient across TCM components

Properties

Download Data

Component: Paris polyphylla ä¸ƒå¶ä¸€æžèŠ±