Component ID |
TCMH2631 |
Latin Name |
Radix polygoni multiflori preparata |
English Name |
Prepared fLeeceflower root |
Chinese Pinyin Name |
Zhi Shou Wu |
中文名 |
制首乌 |
TCM Properties |
Minor Warm,Sweet,Bitter,Punkery |
TCM Meridians |
Liver,Heart,Kidney |
Therapeutic Class English |
For tonifying weakness |
Therapeutic Class Chinese |
补虚 |
Functions |
replenish the liver and the kidney with vital essence and blood, blacken the hair, and strengthen the tendons and bones |
Toxicity |
NA |
Geo-authentic habitats (道地产区) |
NA |
Reference |
CFDA |
Barcode ID |
|
Barcode Source |
Prescription ID | Prescription English Name | Prescription Chinese Name |
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Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
---|---|---|---|---|
TCMT158 | EPHX2 | Epoxide hydratase | Lyase | P34913 |
TCMT2 | MAPT | Microtubule-associated protein tau | Unclassified | P10636 |
TCMT232 | ABCB1 | P-glycoprotein 1 | Transporter | P08183 |
TCMT3 | ALOX15 | Arachidonate 15-lipoxygenase | Oxidoreductase | P16050 |
TCMT39 | PDE5A | Phosphodiesterase 5A | Hydrolase | O76074 |
TCMT41 | IDH1 | Isocitrate dehydrogenase [NADP] cytoplasmic | Oxidoreductase | O75874 |
TCMT8 | KDM4E | Lysine-specific demethylase 4D-like | Oxidoreductase | B2RXH2 |
Target ID | Target Name |
---|---|
TCMT1464 | Hepatitis B virus |
TCMT1465 | Entamoeba histolytica |
Ingredient ID: TCMC1889
Formula: C16H12O5
Ingredient ID: TCMC1362
Formula: C21H20O6
Ingredient ID | Formulae | Name | MW | AlogP | MlogP | XlogP | # HBA | # HBD | PSA | # Rotatable Bond | # Ring | # Heacy Atom | Lipinski RO5 Violation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
TCMC1362 | C21H20O6 | Icaritin | 368.13 | -0.055 | 3.11 | 3.904 | 2 | 3 | 96.22 | 10 | 3 | 27 | 0 |
TCMC1889 | C16H12O5 | Physcion | 284.07 | -0.858 | 2.67 | 1.183 | 2 | 2 | 83.83 | 5 | 3 | 21 | 0 |