Component: Radix polygoni multiflori preparata 制首乌


Description of the Component

Component ID
TCMH2631
Latin Name
Radix polygoni multiflori preparata
English Name
Prepared fLeeceflower root
Chinese Pinyin Name
Zhi Shou Wu
中文名
制首乌
TCM Properties
Minor Warm,Sweet,Bitter,Punkery
TCM Meridians
Liver,Heart,Kidney
Therapeutic Class English
For tonifying weakness
Therapeutic Class Chinese
补虚
Functions
replenish the liver and the kidney with vital essence and blood, blacken the hair, and strengthen the tendons and bones
Toxicity
NA
Geo-authentic habitats (道地产区)
NA
Reference
CFDA
Barcode ID
Barcode Source

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT158 EPHX2 Epoxide hydratase Lyase P34913
TCMT2 MAPT Microtubule-associated protein tau Unclassified P10636
TCMT232 ABCB1 P-glycoprotein 1 Transporter P08183
TCMT3 ALOX15 Arachidonate 15-lipoxygenase Oxidoreductase P16050
TCMT39 PDE5A Phosphodiesterase 5A Hydrolase O76074
TCMT41 IDH1 Isocitrate dehydrogenase [NADP] cytoplasmic Oxidoreductase O75874
TCMT8 KDM4E Lysine-specific demethylase 4D-like Oxidoreductase B2RXH2


Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1464 Hepatitis B virus
TCMT1465 Entamoeba histolytica

Ingredient Structrues

Ingredient ID: TCMC1889
Formula: C16H12O5

Ingredient ID: TCMC1362
Formula: C21H20O6

Properties

Ingredient ID Formulae Name MW AlogP MlogP XlogP # HBA # HBD PSA # Rotatable Bond # Ring # Heacy Atom Lipinski RO5 Violation
TCMC1362 C21H20O6 Icaritin 368.13 -0.055 3.11 3.904 2 3 96.22 10 3 27 0
TCMC1889 C16H12O5 Physcion 284.07 -0.858 2.67 1.183 2 2 83.83 5 3 21 0

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1. General Information of the Component  
2. TCM Prescriptions with the Component  
3. Putative Targets  
4. Activity & References for Filtering Putative Targets  
5. Ingredient Data & Chemical Structure Information (Properties, InChI, InChIkey, SMILES, etc.)