Prescription ID | TCMFx1340 |
Pinyin Name | Gu Ci Wan |
Chinese Name | 骨刺丸 |
English Name | Bone Piercing Bolus |
Function Description | 痹病 |
Indications | Arthritis, Rheumatoid arthritis |
Disease ICD-11 Category |
FA2Z [Inflammatory arthropathies, unspecified, 炎性关节病,未特指的
]; FA20 [Rheumatoid arthritis, 类风湿性关节炎 ]; |
Human Tissues Associated with Indication | SkeletalMuscle, Blood |
Reference | Chinese pharmacopoeia (2015) |
Reference Book/link | ISBN 978-7-5067-7337-9 |
Component ID | Latin Name | Chinese Name | Component Quantity | Barcode |
---|---|---|---|---|
TCMH1966 | Rehmannia glutinosa | 熟地黄 | TCMH1966 | ITSAH4578-14 |
TCMH700 | Drynaria fortunei | 骨碎补 | TCMH700 | GBVM3977-11 |
TCMH1405 | Strychnos nux-vomica | 马钱子 | TCMH1405 | PPBI045-16 |
TCMH1036 | Spatholobus suberectus | 鸡血藤 | TCMH1036 | ITSAK2607-14 |
TCMH1740 | Cistanche deserticola | 肉苁蓉 | TCMH1740 | ITSAM2511-14 |
TCMH802 | Radix notoginseng | 汉三七 | TCMH802 | |
TCMH1753 | Boswellia carterii | 乳香 | TCMH1753 | |
TCMH1508 | Commiphora myrrha | 没药 | TCMH1508 | MH522406 |
TCMH305 | Cnidium officinale | 川芎 | TCMH305 | ITSAP4207-14 |
Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
---|---|---|---|---|
TCMT112 | ADORA3 | Adenosine A3 receptor | GPCR | P0DMS8 |
TCMT131 | ACHE | Acetylcholinesterase | Hydrolase | P22303 |
TCMT133 | CA1 | Carbonic anhydrase I | Lyase | P00915 |
TCMT134 | CA2 | Carbonic anhydrase II | Lyase | P00918 |
TCMT135 | CA14 | Carbonic anhydrase XIV | Lyase | Q9ULX7 |
TCMT136 | CA12 | Carbonic anhydrase XII | Lyase | O43570 |
TCMT138 | CA7 | Carbonic anhydrase VII | Lyase | P43166 |
TCMT142 | CA4 | Carbonic anhydrase IV | Lyase | P22748 |
TCMT156 | CYP19A1 | Cytochrome P450 19A1 | Oxidoreductase | P11511 |
TCMT162 | UGT1A1 | UDP-glucuronosyltransferase 1-1 | Transferase | P22309 |
TCMT174 | HSD11B1 | 11-beta-hydroxysteroid dehydrogenase 1 | Oxidoreductase | P28845 |
TCMT187 | AR | Androgen Receptor | Nuclear receptor | P10275 |
TCMT215 | CYP1A1 | Cytochrome P450 1A1 | Oxidoreductase | P04798 |
TCMT219 | CYP1A2 | Cytochrome P450 1A2 | Oxidoreductase | P05177 |
TCMT223 | AKR1B1 | Aldose reductase | Oxidoreductase | P15121 |
TCMT23 | ALPL | Alkaline phosphatase, tissue-nonspecific isozyme | Hydrolase | P05186 |
TCMT236 | ESR2 | Estrogen receptor beta | Nuclear receptor | Q92731 |
TCMT257 | CYP1B1 | Cytochrome P450 1B1 | Oxidoreductase | Q16678 |
TCMT295 | MMP1 | Matrix metalloproteinase-1 | Hydrolase | P03956 |
TCMT296 | ADORA1 | Adenosine A1 receptor | GPCR | P30542 |
TCMT297 | FABP4 | Fatty acid binding protein adipocyte | Unclassified | P15090 |
TCMT298 | FABP3 | Fatty acid binding protein muscle | Hydrolase | P05413 |
TCMT306 | MMP2 | Matrix metalloproteinase-2 | Hydrolase | P08253 |
TCMT321 | MMP9 | Matrix metalloproteinase 9 | Hydrolase | P14780 |
TCMT332 | AOC3 | Amine oxidase, copper containing | Oxidoreductase | Q16853 |
TCMT344 | AOX1 | Aldehyde oxidase | Oxidoreductase | Q06278 |
TCMT591 | ESRRA | Estrogen-related receptor alpha | Nuclear receptor | P11474 |
TCMT592 | XDH | Xanthine dehydrogenase | Oxidoreductase | P47989 |
TCMT597 | SLC28A3 | Solute carrier family 28 member 3 | Transporter | Q9HAS3 |
TCMT599 | UBE2N | Ubiquitin-conjugating enzyme E2 N | Transferase | P61088 |
TCMT613 | NR3C1 | Glucocorticoid receptor | Nuclear receptor | P04150 |
TCMT614 | EGLN1 | Egl nine homolog 1 | Oxidoreductase | Q9GZT9 |
TCMT63 | PPARA | Peroxisome proliferator-activated receptor alpha | Nuclear receptor | Q07869 |
TCMT637 | SIRT3 | NAD-dependent deacetylase sirtuin 3 | Hydrolase | Q9NTG7 |
TCMT638 | SIRT2 | NAD-dependent deacetylase sirtuin 2 | Hydrolase | Q8IXJ6 |
TCMT65 | HSD17B1 | Estradiol 17-beta-dehydrogenase 1 | Oxidoreductase | P14061 |
TCMT709 | SLC28A2 | Sodium/nucleoside cotransporter 2 | Transporter | O43868 |
TCMT710 | SLC28A1 | Sodium/nucleoside cotransporter 1 | Transporter | O00337 |
TCMT752 | CSNK2A1 | Casein kinase II alpha | Kinase | P68400 |
TCMT783 | NR3C2 | Mineralocorticoid receptor | Nuclear receptor | P08235 |
TCMT808 | FABP5 | Fatty acid binding protein epidermal | Unclassified | Q01469 |
TCMT809 | FABP2 | Fatty acid binding protein intestinal | Unclassified | P12104 |
TCMT810 | TLR2 | Toll-like receptor 2 | Unclassified | O60603 |
TCMT82 | ESR1 | Estrogen receptor alpha | Nuclear receptor | P03372 |
TCMT822 | FUT7 | Alpha-(1,3)-fucosyltransferase 7 | Transferase | Q11130 |
TCMT899 | ALDH2 | Aldehyde dehydrogenase | Oxidoreductase | P05091 |
TCMT904 | PGR | Progesterone receptor | Nuclear receptor | P06401 |
TCMT910 | ESRRB | Estrogen-related receptor beta | Nuclear receptor | O95718 |
TCMT974 | GPER1 | G-protein coupled estrogen receptor 1 | GPCR | Q99527 |
TCMT99 | SHBG | Testis-specific androgen-binding protein | Unclassified | P04278 |
Target ID | Target Name |
---|---|
TCMT1175 | Human immunodeficiency virus |
TCMT1178 | Actinomyces viscosus |
TCMT1181 | Mycobacterium tuberculosis H37Ra |
TCMT1186 | Plasmodium yoelii yoelii |
TCMT1189 | Pseudomonas fluorescens |
TCMT1209 | Staphylococcus haemolyticus |
TCMT1210 | Streptococcus sobrinus |
TCMT1211 | Fusobacterium nucleatum |
TCMT1212 | Verticillium dahliae |
TCMT1214 | Enterococcus faecium |
TCMT1218 | Staphylococcus aureus |
TCMT1219 | Enterococcus |
TCMT1222 | Plasmodium falciparum D6 |
TCMT1223 | Staphylococcus epidermidis |
TCMT1226 | Klebsiella pneumoniae |
TCMT1229 | Enterococcus faecalis |
TCMT1232 | Pseudomonas aeruginosa |
TCMT1234 | Bacillus coagulans |
TCMT1235 | Clostridium sporogenes |
TCMT1236 | Mycobacterium bovis |
TCMT1237 | Mycobacterium kansasii |
TCMT1238 | Mycobacterium xenopi |
TCMT1239 | Mycobacterium marinum |
TCMT1245 | Phytophthora cactorum |
TCMT1246 | Escherichia coli |
TCMT1248 | Hepatitis C virus |
TCMT1251 | Candida albicans |
TCMT1253 | Penicillium chrysogenum |
TCMT1255 | Human immunodeficiency virus 1 |
TCMT1286 | Bacillus cereus |
TCMT1321 | Staphylococcus hominis |
TCMT1343 | Staphylococcus simulans |
TCMT1344 | Staphylococcus sciuri |
TCMT1346 | Helicobacter pylori |
TCMT1349 | Helicobacter pylori SS1 |
TCMT1361 | Neisseria meningitidis |
TCMT1370 | Prevotella melaninogenica |
TCMT1382 | Plasmodium falciparum (isolate K1 / Thailand) |
TCMT1408 | Colletotrichum gloeosporioides |
TCMT1412 | Salmonella typhimurium |
TCMT1438 | Plasmodium falciparum |
TCMT1442 | Leishmania donovani |
TCMT1448 | Enterobacter aerogenes |
TCMT1449 | Influenza A virus |
TCMT1454 | Bacillus subtilis |
TCMT1455 | Mycobacterium tuberculosis H37Rv |
TCMT1457 | Leishmania major |
TCMT1458 | Filobasidiella neoformans |
TCMT1462 | Streptococcus mutans |
TCMT1463 | Mycobacterium tuberculosis |
TCMT1464 | Hepatitis B virus |
TCMT1465 | Entamoeba histolytica |
GO Term | GO Name | Enriched Genes | Log10 Adjusted P-value |
---|
KEGG Pathway ID | Enriched Genes | Log10 Adjusted P-value |
---|