Prescription Description
| Prescription ID | TCMF2831 |
| Pinyin Name | Gan Lu Yin |
| Chinese Name | 甘露饮 |
| English Name | Gan Lu Decoction |
| Function Description | 治丈夫, 妇人, 小儿胃中客热, 牙宣口气, 齿龈肿烂, 时出脓血, 目睑垂重, 常欲合闭; 或频饥烦, 不欲饮食, 及赤目肿痛, 不任凉药, 口舌生疮, 咽喉肿痛, 疮疹已发, 未发, 皆可服之又疗脾胃受湿, 瘀热在里, 或醉饱房劳, 湿热相搏, 致生疸病, 身面皆黄, 肢体微肿, 胸满气短, 大便不调, 小便黄涩, 或时身热, 并皆治之 |
| Indications | None |
| Disease ICD-11 Category | |
| Human Tissues Associated with Indication | Lung |
| Reference | SATCM |
| Reference Book/link | http://www.satcm.gov.cn/ |
Prescription Components
| Component ID | Latin Name | Chinese Name | Component Quantity | Barcode |
|---|---|---|---|---|
| TCMH1617 | Eriobotrya japonica thunb | 枇杷叶 | TCMH1617 | ITSAN1970-14 |
| TCMH1966 | Rehmannia glutinosa | 熟地黄 | TCMH1966 | ITSAH4578-14 |
| TCMH2092 | Asparagus cochinchinensis | 天门冬 | TCMH2092 | ITSAJ4142-14 |
| TCMH2618 | Citrus aurantium | 枳壳 | TCMH2618 | ITSAA1279-14 |
| TCMH1846 | Artemisia capillaris | 山茵陈 | TCMH1846 | ITSAN1371-14 |
| TCMH1896 | Radix rehmanniae | 生地黄 | TCMH1896 | |
| TCMH1428 | Ophiopogon japonicus | 麦门冬 | TCMH1428 | ITSAJ4140-14 |
| TCMH1933 | Herba dendrobii | 石斛 | TCMH1933 | |
| TCMH628 | Glycyrrhiza uralensis | 甘草 | TCMH628 | ITSAM892-14 |
| TCMH986 | Scutellaria baicalensis | 黄芩 | TCMH986 | ITSAP4211-14 |
Targeted Human Proteins by the Ingredients of Prescription
| Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
|---|---|---|---|---|
| TCMT101 | PTPN1 | Protein-tyrosine phosphatase 1B | Hydrolase | P18031 |
| TCMT112 | ADORA3 | Adenosine A3 receptor | GPCR | P0DMS8 |
| TCMT127 | PARP1 | Poly [ADP-ribose] polymerase-1 | Transferase | P09874 |
| TCMT128 | TNKS2 | Tankyrase-2 | Transferase | Q9H2K2 |
| TCMT129 | TNKS | Tankyrase-1 | Transferase | O95271 |
| TCMT130 | ALOX5 | Arachidonate 5-lipoxygenase | Oxidoreductase | P09917 |
| TCMT131 | ACHE | Acetylcholinesterase | Hydrolase | P22303 |
| TCMT133 | CA1 | Carbonic anhydrase I | Lyase | P00915 |
| TCMT134 | CA2 | Carbonic anhydrase II | Lyase | P00918 |
| TCMT135 | CA14 | Carbonic anhydrase XIV | Lyase | Q9ULX7 |
Showing 1 to 10 of 97 entries
Targeted Pathogenic Microbes by the Ingredients of Prescription
| Target ID | Target Name |
|---|---|
| TCMT1170 | Enterobacter cloacae |
| TCMT1175 | Human immunodeficiency virus |
| TCMT1176 | Streptococcus pneumoniae |
| TCMT1178 | Actinomyces viscosus |
| TCMT1179 | Escherichia coli ATCC 8739 |
| TCMT1181 | Mycobacterium tuberculosis H37Ra |
| TCMT1186 | Plasmodium yoelii yoelii |
| TCMT1191 | Bacillus megaterium |
| TCMT1208 | Escherichia coli K12 |
| TCMT1209 | Staphylococcus haemolyticus |
Showing 1 to 10 of 77 entries
Gene Ontology Associated to Targeted Human Proteins
| GO Term | GO Name | Enriched Genes | Log10 Adjusted P-value |
|---|---|---|---|
| [BP] GO:0000302 | response to reactive oxygen species | AKR1B1, AKR1C3, AXL, BCL2, CYP1B1, MMP9, SRC | 3.41384 |
| [BP] GO:0001101 | response to acid chemical | AKR1B1, AKR1C3, FABP3, HSD17B2, KDR, MMP2, SRC | 2.05184 |
| [BP] GO:0001503 | ossification | ALOX15, ALPL, BCL2, MMP2, MMP9 | 2.37531 |
| [BP] GO:0001666 | response to hypoxia | ADORA1, BCL2, CYP1A1, HSD11B2, MMP2, PPARA, SRC | 2.52493 |
| [BP] GO:0001676 | long-chain fatty acid metabolic process | AKR1C3, ALOX15, CBR1, CYP1A1, CYP1A2, CYP1B1, TBXAS1 | 4.72739 |
| [BP] GO:0001934 | positive regulation of protein phosphorylation | ADORA1, ALOX15, APP, BCL2, CDC25B, FLT3, KDR, KIT, MMP9, PTPN1, SRC, XDH | 2.21031 |
| [BP] GO:0002318 | myeloid progenitor cell differentiation | FLT3, KIT | 2.02753 |
| [BP] GO:0002320 | lymphoid progenitor cell differentiation | BCL2, FLT3, KIT | 3.01928 |
| [BP] GO:0003006 | developmental process involved in reproduction | AKR1C3, ALPL, AXL, BCL2, CDC25B, CYP19A1, ESR1, ESRRB, HSD17B2, KIT, SRC | 3.09356 |
| [BP] GO:0003014 | None | ADORA1, AKR1B1, AKR1C3, BCL2, HSD11B2 | 2.6494 |
Showing 1 to 10 of 260 entries
KEGG Pathways Associated to Targeted Human Proteins
| KEGG Pathway ID | Enriched Genes | Log10 Adjusted P-value |
|---|---|---|
| ABC transporters_Homo sapiens_hsa02010 | ABCB1 | 0.6503 |
| Acute myeloid leukemia_Homo sapiens_hsa05221 | FLT3, KIT, PIM1 | 2.252 |
| Adherens junction_Homo sapiens_hsa04520 | PTPN1, CSNK2A1, SRC, MET, IGF1R | 4.1382 |
| Adipocytokine signaling pathway_Homo sapiens_hsa04920 | PPARA | 0.5558 |
| Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | BCL2 | 0.3839 |
| AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | MMP2, BCL2, PIM1, F3 | 2.5971 |
| Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | HSD11B2 | 0.694 |
| Alzheimer's disease_Homo sapiens_hsa05010 | APP | 0.3563 |
| AMPK signaling pathway_Homo sapiens_hsa04152 | IGF1R | 0.4174 |
| Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | BCL2 | 0.63 |
Showing 1 to 10 of 139 entries
Target Exprsssion in Healthy Human Tissues (protein & mRNA level)
Protein expression data was from the "Human Proteome Map" datasetmRNA expression data was from the "GTEx" dataset
Average Target Expression (Fold Change) in Multiple Disease Conditions
Fold Change with Corresponding Normal SamplesClick each cell within the heatmap to access gene expression of individual patient samples