Prescription Description
| Prescription ID | TCMF282 |
| Pinyin Name | Xiao Er Jie Biao Ke Li |
| Chinese Name | 小儿解表颗粒 |
| English Name | Xiao Er Jie Biao Granules |
| Function Description | 感冒 |
| Indications | Common cold disorder, Common cold |
| Disease ICD-11 Category |
SA60 [Common cold disorder (TM1), 感冒 (TM1)
]; CA00 [Acute nasopharyngitis, 急性鼻咽炎 ]; |
| Human Tissues Associated with Indication | Lung, Blood |
| Reference | Chinese pharmacopoeia (2015) |
| Reference Book/link | ISBN 978-7-5067-7337-9 |
Prescription Components
| Component ID | Latin Name | Chinese Name | Component Quantity | Barcode |
|---|---|---|---|---|
| TCMH1127 | Lonicera japonica | 金银花 | TCMH1127 | ITSAI3881-14 |
| TCMH1272 | Forsythia suspensa | 连翘 | TCMH1272 | ITSAJ4444-14 |
| TCMH1562 | Arctium lappa | 牛蒡子 | TCMH1562 | ITSAI1776-14 |
| TCMH1632 | Taraxacum mongolicum | 蒲公英 | TCMH1632 | ITSAG679-14 |
| TCMH986 | Scutellaria baicalensis | 黄芩 | TCMH986 | ITSAP4211-14 |
| TCMH562 | Saposhnikovia divaricata | 防风 | TCMH562 | ITSAE3225-14 |
| TCMH2722 | Perilla frutescens var. arguta | 紫苏叶 | TCMH2722 | ITSAF2620-14 |
| TCMH1142 | Schizonepetae spica | 荆芥穗 | TCMH1142 | |
| TCMH677 | Pueraria lobata | 葛根 | TCMH677 | ITSAJ4206-14 |
| TCMH1716 | Calculus bovis artificiosus | 人工牛黄 | TCMH1716 |
Targeted Human Proteins by the Ingredients of Prescription
| Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
|---|---|---|---|---|
| TCMT100 | TTR | Transthyretin | Unclassified | P02766 |
| TCMT101 | PTPN1 | Protein-tyrosine phosphatase 1B | Hydrolase | P18031 |
| TCMT102 | ACP1 | Low molecular weight phosphotyrosine protein phosphatase | Hydrolase | P24666 |
| TCMT103 | PTPRF | Receptor-type tyrosine-protein phosphatase F (LAR) | Hydrolase | P10586 |
| TCMT112 | ADORA3 | Adenosine A3 receptor | GPCR | P0DMS8 |
| TCMT114 | CNR2 | Cannabinoid CB2 receptor | GPCR | P34972 |
| TCMT115 | CNR1 | Cannabinoid CB1 receptor | GPCR | P21554 |
| TCMT126 | TERT | Telomerase reverse transcriptase | Transferase | O14746 |
| TCMT127 | PARP1 | Poly [ADP-ribose] polymerase-1 | Transferase | P09874 |
| TCMT128 | TNKS2 | Tankyrase-2 | Transferase | Q9H2K2 |
Showing 1 to 10 of 103 entries
Targeted Pathogenic Microbes by the Ingredients of Prescription
| Target ID | Target Name |
|---|---|
| TCMT1170 | Enterobacter cloacae |
| TCMT1176 | Streptococcus pneumoniae |
| TCMT1178 | Actinomyces viscosus |
| TCMT1181 | Mycobacterium tuberculosis H37Ra |
| TCMT1189 | Pseudomonas fluorescens |
| TCMT1191 | Bacillus megaterium |
| TCMT1207 | Legionella pneumophila |
| TCMT1208 | Escherichia coli K12 |
| TCMT1210 | Streptococcus sobrinus |
| TCMT1211 | Fusobacterium nucleatum |
Showing 1 to 10 of 66 entries
Gene Ontology Associated to Targeted Human Proteins
| GO Term | GO Name | Enriched Genes | Log10 Adjusted P-value |
|---|---|---|---|
| [BP] GO:0000302 | response to reactive oxygen species | AKR1B1, APEX1, AXL, CYP1B1, MMP9, SRC | 2.45118 |
| [BP] GO:0001676 | long-chain fatty acid metabolic process | ALOX15, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6 | 4.74538 |
| [BP] GO:0001932 | regulation of protein phosphorylation | ADORA1, ALOX15, APP, AR, CDC25B, FABP4, FLT3, HMGCR, IGF1R, KDR, KIT, MMP9, PTPN1, SRC, XDH | 2.15707 |
| [BP] GO:0001934 | positive regulation of protein phosphorylation | ADORA1, ALOX15, APP, AR, CDC25B, FLT3, HMGCR, KDR, KIT, MMP9, PTPN1, SRC, XDH | 2.55718 |
| [BP] GO:0002318 | myeloid progenitor cell differentiation | FLT3, KIT | 2.0368 |
| [BP] GO:0002521 | leukocyte differentiation | AXL, FLT3, FUT7, GLO1, KIT, MMP9, RORC | 2.43015 |
| [BP] GO:0002682 | regulation of immune system process | ADORA1, ALOX15, APP, AXL, CA2, CNR1, CNR2, CYP19A1, ESR1, ESRRA, KIT, MMP12, MMP2, PTPN1, PTPRS, SRC | 2.20522 |
| [BP] GO:0002683 | negative regulation of immune system process | ADORA1, ALOX15, AXL, CNR1, CNR2, CYP19A1, MMP12, PTPRS | 2.12247 |
| [BP] GO:0003006 | developmental process involved in reproduction | AR, AXL, CDC25B, CYP19A1, ESR1, ESRRB, HSD17B2, KIT, PGR, SRC | 2.34832 |
| [BP] GO:0006082 | organic acid metabolic process | ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, FABP3, GLO1, PIM1, PPARA, TYR | 2.49163 |
Showing 1 to 10 of 305 entries
KEGG Pathways Associated to Targeted Human Proteins
| KEGG Pathway ID | Enriched Genes | Log10 Adjusted P-value |
|---|---|---|
| ABC transporters_Homo sapiens_hsa02010 | ABCB1 | 0.6131 |
| Acute myeloid leukemia_Homo sapiens_hsa05221 | FLT3, KIT, PIM1 | 2.2393 |
| Adherens junction_Homo sapiens_hsa04520 | PTPN1, CSNK2A1, SRC, MET, IGF1R | 4.1018 |
| Adipocytokine signaling pathway_Homo sapiens_hsa04920 | PPARA | 0.5013 |
| AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | MMP2, PIM1 | 0.9462 |
| Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | NR3C2 | 0.6498 |
| Alzheimer's disease_Homo sapiens_hsa05010 | APP | 0.3226 |
| AMPK signaling pathway_Homo sapiens_hsa04152 | HMGCR, IGF1R | 0.8283 |
| Arachidonic acid metabolism_Homo sapiens_hsa00590 | CBR1, ALOX5, ALOX15 | 2.1525 |
| Axon guidance_Homo sapiens_hsa04360 | MET | 0.3774 |
Showing 1 to 10 of 126 entries
Target Exprsssion in Healthy Human Tissues (protein & mRNA level)
Protein expression data was from the "Human Proteome Map" datasetmRNA expression data was from the "GTEx" dataset
Average Target Expression (Fold Change) in Multiple Disease Conditions
Fold Change with Corresponding Normal SamplesClick each cell within the heatmap to access gene expression of individual patient samples