Prescription Description
| Prescription ID | TCMF1153 |
| Pinyin Name | Gan Mao Shu Ke Li |
| Chinese Name | 感冒舒颗粒 |
| English Name | Gan Mao Shu Granules |
| Function Description | 感冒 |
| Indications | Common cold disorder, Common cold |
| Disease ICD-11 Category |
SA60 [Common cold disorder (TM1), 感冒 (TM1)
]; CA00 [Acute nasopharyngitis, 急性鼻咽炎 ]; |
| Human Tissues Associated with Indication | Lung, Blood |
| Reference | Chinese pharmacopoeia (2015) |
| Reference Book/link | ISBN 978-7-5067-7337-9 |
Prescription Components
| Component ID | Latin Name | Chinese Name | Component Quantity | Barcode |
|---|---|---|---|---|
| TCMH381 | Isatis indigotica | 大青叶 | TCMH381 | KJ765825 |
| TCMH1272 | Forsythia suspensa | 连翘 | TCMH1272 | ITSAJ4444-14 |
| TCMH1141 | Schizonepeta tenuifolia | 荆芥 | TCMH1141 | ITSAL858-14 |
| TCMH562 | Saposhnikovia divaricata | 防风 | TCMH562 | ITSAE3225-14 |
| TCMH188 | Mentha haplocalyx | 薄荷 | TCMH188 | HM595443 |
| TCMH1562 | Arctium lappa | 牛蒡子 | TCMH1562 | ITSAI1776-14 |
| TCMH1080 | Platycodon grandiflorum | 桔梗 | TCMH1080 | ITSAJ4293-14 |
| TCMH118 | Angelica dahurica | 白芷 | TCMH118 | ITSAK3312-14 |
| TCMH628 | Glycyrrhiza uralensis | 甘草 | TCMH628 | ITSAM892-14 |
Targeted Human Proteins by the Ingredients of Prescription
| Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
|---|---|---|---|---|
| TCMT100 | TTR | Transthyretin | Unclassified | P02766 |
| TCMT101 | PTPN1 | Protein-tyrosine phosphatase 1B | Hydrolase | P18031 |
| TCMT102 | ACP1 | Low molecular weight phosphotyrosine protein phosphatase | Hydrolase | P24666 |
| TCMT103 | PTPRF | Receptor-type tyrosine-protein phosphatase F (LAR) | Hydrolase | P10586 |
| TCMT112 | ADORA3 | Adenosine A3 receptor | GPCR | P0DMS8 |
| TCMT127 | PARP1 | Poly [ADP-ribose] polymerase-1 | Transferase | P09874 |
| TCMT128 | TNKS2 | Tankyrase-2 | Transferase | Q9H2K2 |
| TCMT129 | TNKS | Tankyrase-1 | Transferase | O95271 |
| TCMT130 | ALOX5 | Arachidonate 5-lipoxygenase | Oxidoreductase | P09917 |
| TCMT131 | ACHE | Acetylcholinesterase | Hydrolase | P22303 |
Showing 1 to 10 of 91 entries
Targeted Pathogenic Microbes by the Ingredients of Prescription
| Target ID | Target Name |
|---|---|
| TCMT1170 | Enterobacter cloacae |
| TCMT1175 | Human immunodeficiency virus |
| TCMT1176 | Streptococcus pneumoniae |
| TCMT1178 | Actinomyces viscosus |
| TCMT1179 | Escherichia coli ATCC 8739 |
| TCMT1181 | Mycobacterium tuberculosis H37Ra |
| TCMT1186 | Plasmodium yoelii yoelii |
| TCMT1189 | Pseudomonas fluorescens |
| TCMT1206 | Influenza A virus (A/PR/8/34(H1N1)) |
| TCMT1208 | Escherichia coli K12 |
Showing 1 to 10 of 72 entries
Gene Ontology Associated to Targeted Human Proteins
| GO Term | GO Name | Enriched Genes | Log10 Adjusted P-value |
|---|---|---|---|
| [BP] GO:0000302 | response to reactive oxygen species | AKR1B1, AXL, BCL2, CYP1B1, MMP9, SRC | 2.62314 |
| [BP] GO:0001101 | response to acid chemical | AKR1B1, DHFR, FABP3, HSD17B2, KDR, MMP2, PTGS2, SRC | 2.89721 |
| [BP] GO:0001666 | response to hypoxia | ADORA1, BCL2, CYP1A1, HSD11B2, MMP2, PTGS2, SRC | 2.63293 |
| [BP] GO:0001676 | long-chain fatty acid metabolic process | CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, PTGS2 | 3.74822 |
| [BP] GO:0001932 | regulation of protein phosphorylation | ADORA1, BCL2, CDC25B, FABP4, FLT3, HMGCR, IGF1R, KDR, KIT, MMP9, PTGS2, PTPN1, SRC, XDH | 2.07345 |
| [BP] GO:0001934 | positive regulation of protein phosphorylation | ADORA1, BCL2, CDC25B, FLT3, HMGCR, KDR, KIT, MMP9, PTGS2, PTPN1, SRC, XDH | 2.35355 |
| [BP] GO:0001952 | regulation of cell-matrix adhesion | BCL2, CDK6, GSK3B, KDR, SRC | 2.6241 |
| [BP] GO:0002237 | response to molecule of bacterial origin | ALPL, AXL, CYP1A1, CYP1A2, IDO1, PTGS2, SRC | 2.35258 |
| [BP] GO:0002318 | myeloid progenitor cell differentiation | FLT3, KIT | 2.11173 |
| [BP] GO:0002320 | lymphoid progenitor cell differentiation | BCL2, FLT3, KIT | 3.11226 |
Showing 1 to 10 of 320 entries
KEGG Pathways Associated to Targeted Human Proteins
| KEGG Pathway ID | Enriched Genes | Log10 Adjusted P-value |
|---|---|---|
| Acute myeloid leukemia_Homo sapiens_hsa05221 | FLT3, KIT, PIM1 | 2.3312 |
| Adherens junction_Homo sapiens_hsa04520 | PTPN1, CSNK2A1, SRC, MET, IGF1R | 4.3621 |
| Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | BCL2 | 0.3927 |
| African trypanosomiasis_Homo sapiens_hsa05143 | IDO1 | 0.7585 |
| AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | MMP2, BCL2, PIM1, F3 | 2.6767 |
| Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | HSD11B2 | 0.724 |
| Alzheimer's disease_Homo sapiens_hsa05010 | GSK3B | 0.3609 |
| AMPK signaling pathway_Homo sapiens_hsa04152 | HMGCR, IGF1R | 0.9363 |
| Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | BCL2 | 0.6529 |
| Apoptosis_Homo sapiens_hsa04210 | BCL2 | 0.4053 |
Showing 1 to 10 of 145 entries
Target Exprsssion in Healthy Human Tissues (protein & mRNA level)
Protein expression data was from the "Human Proteome Map" datasetmRNA expression data was from the "GTEx" dataset
Average Target Expression (Fold Change) in Multiple Disease Conditions
Fold Change with Corresponding Normal SamplesClick each cell within the heatmap to access gene expression of individual patient samples