Description of the Component
Component ID |
TCMH352 |
Latin Name |
Radix heraclei maximi |
English Name |
root of laxflower cowparsnip |
Chinese Pinyin Name |
Da Du Huo |
中文名 |
大独活 |
TCM Properties |
Minor Warm,Pungent,Bitter |
TCM Meridians |
Bladder,Liver |
Therapeutic Class English |
For dispelling wind-dampness |
Therapeutic Class Chinese |
祛风湿 |
Functions |
relieve rheumatic conditions, and remove obstruction from the channels and relieve pain |
Toxicity |
NA |
Geo-authentic habitats (道地产区) |
NA |
Reference |
Chinese Pharmacopoeia (2015) |
Barcode ID |
|
Barcode Source |
TCM Prescriptions with the Component
| Prescription ID | Prescription English Name | Prescription Chinese Name |
|---|---|---|
| TCMFx2516 | Anti-Bone Growth Drink |
Targeted Human Proteins by the Ingredient of Component
| Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
|---|---|---|---|---|
| TCMT125 | GBA | Beta-glucocerebrosidase | Hydrolase | P04062 |
| TCMT207 | BACE1 | Beta-secretase 1 | Protease | P56817 |
| TCMT232 | ABCB1 | P-glycoprotein 1 | Transporter | P08183 |
| TCMT31 | CYP2C19 | Cytochrome P450 2C19 | Oxidoreductase | P33261 |
| TCMT33 | CYP3A4 | Cytochrome P450 3A4 | Oxidoreductase | P08684 |
| TCMT337 | XPO1 | Exportin-1 | Unclassified | O14980 |
| TCMT34 | CYP2D6 | Cytochrome P450 2D6 | Oxidoreductase | P10635 |
| TCMT87 | CYP2C9 | Cytochrome P450 2C9 | Oxidoreductase | P11712 |
Targeted Pathogenic Microbes by the Ingredient of Component
| Target ID | Target Name |
|---|---|
| TCMT1112 | Quinolone resistance protein norA |
| TCMT1463 | Mycobacterium tuberculosis |
Ingredient Structrues
Ingredient ID: TCMC1803
Formula: C15H16O3
Properties
| Ingredient ID | Formulae | Name | MW | AlogP | MlogP | XlogP | # HBA | # HBD | PSA | # Rotatable Bond | # Ring | # Heacy Atom | Lipinski RO5 Violation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TCMC1803 | C15H16O3 | Osthole | 244.11 | 2.0956 | 2.78 | 3.521 | 1 | 0 | 35.53 | 6 | 2 | 18 | 0 |
Download Data
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