TCM Putative Target References: TCMH1866


Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
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Ingredient ID & Structure Target ID Target Name Target Organism Activity Records & Reference
TCMC1803
TCMT337 Exportin-1 Homo sapiens IC50: 1600 (nM), Ref: 20493693
TCMC949
TCMT136 Carbonic anhydrase XII Homo sapiens Ki: 8900 (nM), Ref: 19911821
TCMC949
TCMT135 Carbonic anhydrase XIV Homo sapiens Ki: 48 (nM), Ref: 19911821
TCMC949
TCMT137 Carbonic anhydrase IX Homo sapiens Ki: 9100 (nM), Ref: 19911821
TCMC949
TCMT138 Carbonic anhydrase VII Homo sapiens Ki: 3300 (nM), Ref: 19911821
TCMC949
TCMT139 Carbonic anhydrase VI Homo sapiens Ki: 2000 (nM), Ref: 19911821
TCMC949
TCMT140 Carbonic anhydrase VB Homo sapiens Ki: 5200 (nM), Ref: 19911821
TCMC949
TCMT141 Carbonic anhydrase VA Homo sapiens Ki: 9400 (nM), Ref: 19911821
TCMC949
TCMT142 Carbonic anhydrase IV Homo sapiens Ki: 6800 (nM), Ref: 19911821
TCMC949
TCMT143 Carbonic anhydrase III Homo sapiens Ki: 5600 (nM), Ref: 19911821
TCMC949
TCMT133 Carbonic anhydrase I Homo sapiens Ki: 3100 (nM), Ref: 19911821
Ki: 3100 (nM), Ref: 21067924
Ki: 3100 (nM), Ref: 22137345
Ki: 3100 (nM), Ref: 22077347
Ki: 3100 (nM), Ref: 22365761
Ki: 3100 (nM), Ref: 22377674
Ki: 3100 (nM), Ref: 23241068
Ki: 3100 (nM), Ref: 22892213
Ki: 3100 (nM), Ref: 26688270
TCMC949
TCMT134 Carbonic anhydrase II Homo sapiens Ki: 9200 (nM), Ref: 21067924
Ki: 9200 (nM), Ref: 22137345
Ki: 9200 (nM), Ref: 22077347
Ki: 9200 (nM), Ref: 22365761
Ki: 9200 (nM), Ref: 22377674
Ki: 9200 (nM), Ref: 23241068
Ki: 9200 (nM), Ref: 22892213
Ki: 9200 (nM), Ref: 26688270
TCMC2242
TCMT133 Carbonic anhydrase I Homo sapiens Ki: 7710 (nM), Ref: 22892213
TCMC2242
TCMT138 Carbonic anhydrase VII Homo sapiens Ki: 6270 (nM), Ref: 22892213
TCMC2242
TCMT225 Carbonic anhydrase XIII Homo sapiens Ki: 3150 (nM), Ref: 22892213
TCMC2242
TCMT136 Carbonic anhydrase XII Homo sapiens Ki: 960 (nM), Ref: 22892213
TCMC2242
TCMT137 Carbonic anhydrase IX Homo sapiens Ki: 740 (nM), Ref: 22892213
TCMC405
TCMT506 Protein tyrosine kinase 2 beta Homo sapiens IC50: 2324 (nM), Ref:
TCMC1830
TCMT297 Fatty acid binding protein adipocyte Homo sapiens IC50: 930 (nM), Ref: 15357969
TCMC1830
TCMT298 Fatty acid binding protein muscle Homo sapiens IC50: 2600 (nM), Ref: 15357969
TCMC1830
TCMT808 Fatty acid binding protein epidermal Homo sapiens IC50: 1200 (nM), Ref: 15357969
TCMC1830
TCMT809 Fatty acid binding protein intestinal Homo sapiens IC50: 1700 (nM), Ref: 15357969
TCMC1830
TCMT810 Toll-like receptor 2 Homo sapiens IC50: 5000 (nM), Ref: 16509590
TCMC1830
TCMT64 Peroxisome proliferator-activated receptor delta Homo sapiens IC50: 7400 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1830
TCMT63 Peroxisome proliferator-activated receptor alpha Homo sapiens IC50: 1500 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1551
TCMT206 Cytochrome P450 2A6 Homo sapiens Ki: 1900 (nM), Ref: 16248836
Ki: 1900 (nM), Ref: 16248836
Ki: 800 (nM), Ref: 16248836
Ki: 250 (nM), Ref: 22696418
TCMC1551
TCMT131 Acetylcholinesterase Homo sapiens IC50: 760 (nM), Ref: 23746477
TCMC1551
TCMT268 Cytochrome P450 2A13 Homo sapiens Ki: 40 (nM), Ref: 22696418
TCMC1611
TCMT810 Toll-like receptor 2 Homo sapiens IC50: 5000 (nM), Ref: 16509590
TCMC1611
TCMT63 Peroxisome proliferator-activated receptor alpha Homo sapiens IC50: 5400 (nM), Ref: 10.1007/s00044-012-0285-6
TCMC1961
TCMT206 Cytochrome P450 2A6 Homo sapiens Ki: 600 (nM), Ref: 16248836
TCMC1961
TCMT131 Acetylcholinesterase Homo sapiens IC50: 6480 (nM), Ref: 23746477
TCMC1064
TCMT219 Cytochrome P450 1A2 Homo sapiens IC50: 2437 (nM), Ref: 20696580
TCMC1064
TCMT215 Cytochrome P450 1A1 Homo sapiens IC50: 140 (nM), Ref: 20696580
TCMC1064
TCMT257 Cytochrome P450 1B1 Homo sapiens IC50: 29 (nM), Ref: 20696580

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure Target ID Target Name Target Organism Activity Records & Reference
TCMC1803
TCMT1112 Quinolone resistance protein norA Staphylococcus aureus MIC: 2 (ug/ml), Ref: 10.1039/C4MD00196F
TCMC1858
TCMT1112 Quinolone resistance protein norA Staphylococcus aureus MIC: 4 (ug/ml), Ref: 10.1039/C4MD00196F
TCMC2324
TCMT1462 Streptococcus mutans Streptococcus mutans MIC: 100 (ug/ml), Ref: 1517735
TCMC1803
TCMT1463 Mycobacterium tuberculosis Mycobacterium tuberculosis MIC: 32 (ug/ml), Ref: 23369537
TCMC1830
TCMT1361 Neisseria meningitidis Neisseria meningitidis MIC: 50 (ug/ml), Ref: 19884363
TCMC1830
TCMT1382 Plasmodium falciparum (isolate K1 / Thailand) Plasmodium falciparum K1 IC50: 3.8 (ug/ml), Ref: 20855214
IC50: 3.8 (ug/ml), Ref: 25103602
TCMC1830
TCMT1442 Leishmania donovani Leishmania donovani IC50: 14.5 (ug/ml), Ref: 20855214
TCMC2550
TCMT1393 Vibrio sp. Vibrio sp. MIC: 15 (ug/ml), Ref: 21865038
TCMC801
TCMT1438 Plasmodium falciparum Plasmodium falciparum IC50: 32 (ug/ml), Ref: 15844943
TCMC801
TCMT1465 Entamoeba histolytica Entamoeba histolytica IC50: 52.3 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC1551
TCMT1349 Helicobacter pylori SS1 Helicobacter pylori SS1 MIC: 25 (ug/ml), Ref: 20832915
TCMC2696
TCMT1354 Streptococcus mutans UA159 Streptococcus mutans UA159 MIC: 80 (ug/ml), Ref: 10.1007/s00044-011-9658-5
TCMC2718
TCMT1229 Enterococcus faecalis Enterococcus faecalis MBC: 3.13 (ug/ml), Ref: 12502328
MIC: 3.13 (ug/ml), Ref: 12502328
TCMC2718
TCMT1214 Enterococcus faecium Enterococcus faecium MBC: 3.13 (ug/ml), Ref: 12502328
MIC: 3.13 (ug/ml), Ref: 12502328
TCMC2718
TCMT1218 Staphylococcus aureus Staphylococcus aureus MBC: 3.13 (ug/ml), Ref: 12502328
MIC: 3.13 (ug/ml), Ref: 12502328
MBC: 1.56 (ug/ml), Ref: 12502328
MIC: 1.56 (ug/ml), Ref: 12502328
TCMC1961
TCMT1349 Helicobacter pylori SS1 Helicobacter pylori SS1 MIC: 6.25 (ug/ml), Ref: 20832915
TCMC1064
TCMT1218 Staphylococcus aureus Staphylococcus aureus MIC: 15 (ug/ml), Ref: 11170636
TCMC2822
TCMT1463 Mycobacterium tuberculosis Mycobacterium tuberculosis MIC: 6.25 (ug/ml), Ref: 17845001