Description of the Component
Component ID |
TCMH2339 |
Latin Name |
Rhizoma corydalis |
English Name |
root of corydalis |
Chinese Pinyin Name |
Xuan Hu |
中文名 |
玄胡 |
TCM Properties |
Pungent,Slightly Bitter |
TCM Meridians |
|
Therapeutic Class English |
|
Therapeutic Class Chinese |
|
Functions |
promote the circulation of blood and vital energy, and alleviatepain |
Toxicity |
NA |
Geo-authentic habitats (道地产区) |
NA |
Reference |
CFDA |
Barcode ID |
|
Barcode Source |
Targeted Human Proteins by the Ingredient of Component
| Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
|---|---|---|---|---|
| TCMT33 | CYP3A4 | Cytochrome P450 3A4 | Oxidoreductase | P08684 |
| TCMT34 | CYP2D6 | Cytochrome P450 2D6 | Oxidoreductase | P10635 |
| TCMT36 | HTR1A | Serotonin 1a (5-HT1a) receptor | GPCR | P08908 |
| TCMT46 | F3 | Coagulation factor III | Unclassified | P13726 |
Showing 1 to 4 of 4 entries
Targeted Pathogenic Microbes by the Ingredient of Component
Ingredient Structrues
Ingredient ID: TCMC315
Formula: C21H25NO4
Ingredient ID: TCMC315
| Common Name | 2,3,9,10-Tetramethoxy-6,8,13,13A-Tetrahydro-5H-Isoquinolino[2,1-B]Isoquinoline |
| IUPAC Name | 2,3,9,10-tetramethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline |
| Canonical SMILES | COc1cc2CCN3C(c2cc1OC)Cc1c(C3)c(OC)c(cc1)OC |
| Standard InCHI | InChI=1S/C21H25NO4/c1-23-18-6-5-13-9-17-15-11-20(25-3)19(24-2)10-14(15)7-8-22(17)12-16(13)21(18)26-4/h5-6,10-11,17H,7-9,12H2,1-4H3 |
| Standard InCHIKey | AEQDJSLRWYMAQI-UHFFFAOYSA-N |
| External Identifiers | ChEMBL [CHEMBL187892]; PubChem [5417]; |
| Reference of Component-Ingredient Pair | N/A |
Occurrence of the ingredient across TCM components
| Component ID | Latin Name | Pinyin Name | Chinese Name |
|---|---|---|---|
| TCMH1064 | Coptis chinensis | Jiang Huang Lian | 姜黄连 |
| TCMH1092 | Stephania sinica | Jin Bu Huan | 金不换 |
| TCMH1161 | Coptis chinensis | Jiu Huang Lian | 酒黄连 |
| TCMH1475 | Glycyrrhiza uralensis | Mi Gan Cao | 蜜甘草 |
| TCMH1680 | Sinomenium acutum | Qing Feng Teng | 青风藤 |
| TCMH1899 | Glycyrrhiza uralensis | Sheng Gan Cao | 生甘草 |
| TCMH2135 | Glycyrrhiza uralensis | Tu Gan Cao | 土甘草 |
| TCMH2248 | Corydalis decumbens | Xia Tian Wu | 夏天无 |
| TCMH2330 | Coptis chinensis | Xiong Huang Lian | 雄黄连 |
| TCMH2339 | Rhizoma corydalis | Xuan Hu | 玄胡 |
Showing 1 to 10 of 33 entries
Ingredient ID: TCMC2146
Formula: C20H21NO4
Ingredient ID: TCMC2146
| Common Name | Tetrahydroberberine |
| IUPAC Name | n.a. |
| Canonical SMILES | COc1c(OC)ccc2c1CN1CCc3c(C1C2)cc1c(c3)OCO1 |
| Standard InCHI | InChI=1S/C20H21NO4/c1-22-17-4-3-12-7-16-14-9-19-18(24-11-25-19)8-13(14)5-6-21(16)10-15(12)20(17)23-2/h3-4,8-9,16H,5-7,10-11H2,1-2H3 |
| Standard InCHIKey | VZTUIEROBZXUFA-UHFFFAOYSA-N |
| External Identifiers | ChEMBL [CHEMBL275097]; PubChem [34458]; |
| Reference of Component-Ingredient Pair | 23934770 |
Occurrence of the ingredient across TCM components
| Component ID | Latin Name | Pinyin Name | Chinese Name |
|---|---|---|---|
| TCMH101 | Chelidonium majus | Bai Qu Cai | 白屈菜 |
| TCMH2339 | Rhizoma corydalis | Xuan Hu | 玄胡 |
| TCMH2374 | Phellodendron amurense | Yan Guan Huang Bai | 盐关黄柏 |
| TCMH2376 | Corydalis yanhusuo | Yan Hu Suo | 延胡索 |
| TCMH2552 | Rhizoma corydalis | Yuan Hu | 元胡 |
| TCMH2636 | Rhizoma corydalis | Zhi Xuan Hu | 制玄胡 |
| TCMH717 | Phellodendron amurense | Guan Huang Bai | 关黄柏 |
| TCMH949 | Phellodendron amurense | Huang Bai | 黄柏 |
| TCMH950 | Phellodendron amurense | Huang Bai Fen | 黄柏粉 |
| TCMH951 | Phellodendron amurense | Huang Bai Tan | 黄柏炭 |
Showing 1 to 10 of 10 entries
Ingredient ID: TCMC1957
Formula: C20H19NO5
Ingredient ID: TCMC1957
| Common Name | Protopine |
| IUPAC Name | n.a. |
| Canonical SMILES | CN1CCc2cc3OCOc3cc2C(=O)Cc2c(C1)cc1OCOc1c2 |
| Standard InCHI | InChI=1S/C20H19NO5/c1-21-3-2-12-5-17-20(26-11-23-17)8-15(12)16(22)4-13-6-18-19(25-10-24-18)7-14(13)9-21/h5-8H,2-4,9-11H2,1H3 |
| Standard InCHIKey | ZAALQOFZFANFTF-UHFFFAOYSA-N |
| External Identifiers | ChEMBL [CHEMBL486179]; PubChem [185559]; |
| Reference of Component-Ingredient Pair | N/A |
Occurrence of the ingredient across TCM components
| Component ID | Latin Name | Pinyin Name | Chinese Name |
|---|---|---|---|
| TCMH101 | Chelidonium majus | Bai Qu Cai | 白屈菜 |
| TCMH1205 | Corydalis bungeana | Ku Di Ding | 苦地丁 |
| TCMH1416 | Thalictrum foliolosum | Ma Wei Lian | 马尾连 |
| TCMH1489 | Papaver somniferum | Mi Ying Su Ke | 蜜罂粟壳 |
| TCMH1721 | Panax ginseng | Ren Shen | 人参 |
| TCMH1728 | Panax ginseng | Ren Shen Ye | 人参叶 |
| TCMH1839 | Panax ginseng | Shan Shen | 山参 |
| TCMH2248 | Corydalis decumbens | Xia Tian Wu | 夏天无 |
| TCMH2339 | Rhizoma corydalis | Xuan Hu | 玄胡 |
| TCMH2376 | Corydalis yanhusuo | Yan Hu Suo | 延胡索 |
Showing 1 to 10 of 16 entries
Properties
| Ingredient ID | Formulae | Name | MW | AlogP | MlogP | XlogP | # HBA | # HBD | PSA | # Rotatable Bond | # Ring | # Heacy Atom | Lipinski RO5 Violation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TCMC1957 | C20H19NO5 | Protopine | 353.13 | -0.4401 | 3 | 1.86 | 2 | 0 | 57.23 | 1 | 5 | 26 | 0 |
| TCMC2146 | C20H21NO4 | Tetrahydroberberine | 339.15 | -0.1023 | 3.11 | 2.475 | 1 | 0 | 40.16 | 4 | 5 | 25 | 0 |
| TCMC315 | C21H25NO4 | 2,3,9,10-Tetramethoxy-6,8,13,13A-Tetrahydro-5H-Isoquinolino[2,1-B]Isoquinoline | 355.18 | 0.0968 | 3.22 | 2.548 | 1 | 0 | 40.16 | 8 | 4 | 26 | 0 |
Showing 1 to 3 of 3 entries
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