Component: Rosa roxburghii 刺梨果


Description of the Component

Component ID
TCMH321
Latin Name
Rosa roxburghii
English Name
Prickly pear fruit
Chinese Pinyin Name
Ci Li Guo
中文名
刺梨果
TCM Properties
TCM Meridians
Therapeutic Class English
Therapeutic Class Chinese
Functions
Toxicity
NA
Geo-authentic habitats (道地产区)
NA
Reference
Chinese Pharmacopoeia (2015)
Barcode ID
GBVJ2790-11
Barcode Source
BOLDSYSTEMS

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name
TCMFx7126 Jin Ci Shen Jiu Zheng Recipe 金刺参九正合剂

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT1 EHMT2 Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 Transferase Q96KQ7
TCMT101 PTPN1 Protein-tyrosine phosphatase 1B Hydrolase P18031
TCMT11 HIF1A Hypoxia-inducible factor 1 alpha Transcription factor Q16665
TCMT125 GBA Beta-glucocerebrosidase Hydrolase P04062
TCMT17 POLB DNA polymerase beta Transferase P06746
TCMT18 GAA Lysosomal alpha-glucosidase Hydrolase P10253
TCMT2 MAPT Microtubule-associated protein tau Unclassified P10636
TCMT3 ALOX15 Arachidonate 15-lipoxygenase Oxidoreductase P16050
TCMT31 CYP2C19 Cytochrome P450 2C19 Oxidoreductase P33261
TCMT33 CYP3A4 Cytochrome P450 3A4 Oxidoreductase P08684
TCMT8 KDM4E Lysine-specific demethylase 4D-like Oxidoreductase B2RXH2
TCMT80 MAPK1 MAP kinase ERK2 Kinase P28482
TCMT87 CYP2C9 Cytochrome P450 2C9 Oxidoreductase P11712


Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1121 Sialidase
TCMT1218 Staphylococcus aureus
TCMT1246 Escherichia coli
TCMT1454 Bacillus subtilis
TCMT1458 Filobasidiella neoformans

Ingredient Structrues

Ingredient ID: TCMC386
Formula: C31H46O2

Ingredient ID: TCMC2323
Formula: C18H14O5

Ingredient ID: TCMC1924
Formula: C25H24O6

Ingredient ID: TCMC1800
Formula: C25H24O5

Ingredient ID: TCMC1520
Formula: C23H22O6

Properties

Ingredient ID Formulae Name MW AlogP MlogP XlogP # HBA # HBD PSA # Rotatable Bond # Ring # Heacy Atom Lipinski RO5 Violation
TCMC386 C31H46O2 2-Methyl-3-[(E)-3,7,11,15-Tetramethylhexadec-2-Enyl]Naphthalene-1,4-Dione 450.35 2.7425 4.65 12.011 2 0 34.14 20 2 33 2
TCMC1520 C23H22O6 Macluraxanthone 394.14 0.7307 3.33 3.28 1 3 96.22 9 4 29 0
TCMC1800 C25H24O5 Osajin 404.16 1.1979 3.66 4.382 1 2 75.99 9 4 30 0
TCMC1924 C25H24O6 Pomiferin 420.16 0.7376 3.55 3.848 1 3 96.22 10 4 31 0
TCMC2323 C18H14O5 6-Deoxyjacareubin 310.08 -0.4307 2.89 2.014 1 2 75.99 4 4 23 0

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1. General Information of the Component  
2. TCM Prescriptions with the Component  
3. Putative Targets  
4. Activity & References for Filtering Putative Targets  
5. Ingredient Data & Chemical Structure Information (Properties, InChI, InChIkey, SMILES, etc.)