| GO Term |
GO Name |
Enriched Genes |
Log10 Adjusted P-value |
|
[BP] GO:0065008 |
regulation of biological quality
|
ABCB1, ACHE, ADORA1, AKR1B1, AKR1C3, ALOX15, APEX1, APP, AR, AURKB, AXL, BCL2, CA12, CA2, CA7, CNR1, CNR2, CYP19A1, CYP1A1, CYP1B1, CYP3A4, DRD1, DRD2, EGFR, ESR1, F10, F3, FABP3, FABP4, FLT3, GPR35, HCAR2, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR2C, HTR4, HTR7, INSR, KDR, KIT, MET, MIF, OPRD1, OPRK1, OPRM1, PDE3A, PIK3CA, PIK3CB, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PTGS1, PTGS2, SLC22A1, SLC22A2, SLC22A3, SMAD3, SOAT1, SOAT2, SRC, TEK, TERT, TNKS, TNKS2, TRPV1, XDH |
21.7289 |
|
[BP] GO:0042221 |
response to chemical
|
ABCB1, AKR1B1, AKR1C3, ALOX15, ALPL, APEX1, APP, AR, AXL, BCL2, CA2, CA9, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DNMT1, DRD1, DRD2, EGFR, ESR1, ESRRA, FABP3, FABP4, FLT3, HSD11B2, HSD17B2, HSPA1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR2C, HTR5A, IGF1R, INSR, KDR, KIT, MMP2, MMP9, NR3C1, OPRD1, OPRK1, OPRM1, PDE3A, PDE3B, PIK3CA, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, RORC, SMAD3, SRC, TEK, TERT, TRPV1, TYR |
18.7088 |
|
[BP] GO:1901700 |
response to oxygen-containing compound
|
AKR1B1, AKR1C3, ALPL, APEX1, APP, AR, AXL, BCL2, CA9, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DNMT1, DRD1, DRD2, EGFR, ESR1, ESRRA, FABP3, HSD11B2, HSD17B2, HTR1B, HTR5A, IGF1R, INSR, MMP2, MMP9, NR3C1, OPRK1, OPRM1, PDE3A, PDE3B, PIK3CA, POLB, PPARA, PRKCB, PRKCD, PRKCE, PTGS2, RORC, SRC, TEK, TRPV1, TYR |
18.0938 |
|
[BP] GO:0010033 |
response to organic substance
|
AKR1B1, AKR1C3, ALOX15, ALPL, APEX1, APP, AR, AXL, BCL2, CA2, CA9, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DNMT1, DRD1, DRD2, EGFR, ESR1, ESRRA, FABP3, FABP4, FLT3, HSD11B2, HSD17B2, HSPA1A, HTR1B, HTR5A, IGF1R, INSR, KDR, KIT, MMP2, NR3C1, OPRD1, OPRK1, OPRM1, PDE3A, PDE3B, PIK3CA, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, RORC, SMAD3, SRC, TEK, TRPV1, TYR |
18.0519 |
|
[BP] GO:0010647 |
positive regulation of cell communication
|
ADORA1, AKR1B1, AKR1C3, ALOX15, APP, AR, AXL, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, EGFR, F10, F3, FLT3, GPR35, HCAR2, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, OPRK1, OPRM1, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
16.2547 |
|
[BP] GO:0023056 |
positive regulation of signaling
|
ADORA1, AKR1B1, AKR1C3, ALOX15, APP, AR, AXL, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, EGFR, F10, F3, FLT3, GPR35, HCAR2, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, OPRK1, OPRM1, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
16.2265 |
|
[BP] GO:0014070 |
response to organic cyclic compound
|
AKR1C3, ALPL, APEX1, APP, AR, BCL2, CA2, CA9, CNR1, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, EGFR, ESR1, ESRRA, FLT3, HSD11B2, HTR1B, HTR5A, NR3C1, OPRK1, OPRM1, PDE3A, PRKCE, PRKCG, PTGS2, RORC, SRC, TEK, TRPV1, TYR |
15.216 |
|
[BP] GO:0009719 |
response to endogenous stimulus
|
AKR1B1, AKR1C3, ALPL, APEX1, APP, AR, BCL2, CA2, CA9, CSNK2A1, CYP1A2, DNMT1, DRD1, EGFR, ESR1, ESRRA, FABP3, FLT3, HSD11B2, HTR1B, HTR5A, IGF1R, INSR, KIT, MMP2, NR3C1, OPRK1, OPRM1, PDE3A, PDE3B, PPARA, PRKCD, PRKCE, PTGS2, SMAD3, SRC, TEK, TRPV1 |
14.724 |
|
[BP] GO:0007210 |
None
|
HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7 |
14.5646 |
|
[BP] GO:0098664 |
None
|
HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7 |
14.5646 |
|
[BP] GO:1902533 |
positive regulation of intracellular signal transduction
|
ADORA1, AKR1B1, AKR1C3, ALOX15, APP, AR, AXL, BCL2, CYP1B1, DRD2, EGFR, F10, F3, FLT3, GPR35, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, INSR, KDR, KIT, MET, MIF, OPRK1, OPRM1, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
14.1847 |
|
[BP] GO:0009967 |
positive regulation of signal transduction
|
ADORA1, AKR1B1, AKR1C3, ALOX15, APP, AR, AXL, BCL2, CSNK2A1, CYP1B1, DRD2, EGFR, F10, F3, FLT3, GPR35, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, OPRK1, OPRM1, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
14.1223 |
|
[BP] GO:0010646 |
regulation of cell communication
|
ACHE, ADORA1, AKR1B1, AKR1C3, ALOX15, APP, AR, AURKB, AXL, BACE1, BCL2, CA2, CA7, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, F10, F3, FLT3, GPR35, HCAR2, HSPA1A, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, NUAK1, OPRK1, OPRM1, PDE10A, PDE3B, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
13.7523 |
|
[BP] GO:0006629 |
lipid metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, AKR1C3, ALOX15, ALOX5, APP, CBR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DRD2, EGFR, ESR1, FABP3, FABP4, FUT7, HSD11B1, HSD11B2, HSD17B1, HSD17B2, KIT, MET, MIF, PDE3A, PIK3CA, PIK3CB, PPARA, PTGS1, PTGS2, SOAT1, SOAT2, TRPV1 |
13.7198 |
|
[BP] GO:0023051 |
regulation of signaling
|
ACHE, ADORA1, AKR1B1, AKR1C3, ALOX15, APP, AR, AURKB, AXL, BACE1, BCL2, CA2, CA7, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, F10, F3, FLT3, GPR35, HCAR2, HSPA1A, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, NUAK1, OPRK1, OPRM1, PDE10A, PDE3B, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
13.5118 |
|
[BP] GO:1902531 |
regulation of intracellular signal transduction
|
ADORA1, AKR1B1, AKR1C3, ALOX15, APP, AR, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, F10, F3, FLT3, GPR35, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, KIT, MET, MIF, MMP9, NUAK1, OPRK1, OPRM1, PDE10A, PDE3B, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
13.4182 |
|
[BP] GO:0048522 |
positive regulation of cellular process
|
ACHE, ADORA1, AKR1B1, AKR1C3, ALOX15, APEX1, APP, AR, AURKB, AXL, BCL2, CA2, CA7, CDC25B, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FLT3, GPR35, HCAR2, HSPA1A, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, KIT, MET, MIF, MMP1, MMP12, MMP2, MMP9, NR3C1, OPRD1, OPRK1, OPRM1, PDE3A, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SOAT1, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
13.2711 |
|
[BP] GO:0009725 |
response to hormone
|
AKR1B1, AKR1C3, ALPL, APEX1, AR, BCL2, CA2, CA9, CSNK2A1, CYP1A2, EGFR, ESR1, ESRRA, FABP3, FLT3, HSD11B2, HTR1B, HTR5A, INSR, KIT, NR3C1, OPRK1, PDE3B, PPARA, PRKCD, PRKCE, PTGS2, SRC, TEK, TRPV1 |
13.0823 |
|
[BP] GO:0042493 |
response to drug
|
ABCB1, AKR1B1, APEX1, AXL, BCL2, CA9, CNR1, CNR2, CYP1A1, CYP1B1, DRD1, DRD2, EGFR, FABP3, HSD11B2, HTR1B, HTR2A, HTR2B, HTR2C, KDR, NR3C1, OPRK1, OPRM1, PDE3A, POLB, PRKCD, PRKCE, PRKCG, PTGS2, SRC, TRPV1 |
12.7326 |
|
[BP] GO:0070887 |
cellular response to chemical stimulus
|
AKR1B1, AKR1C3, ALOX15, ALPL, APEX1, APP, AR, AXL, BCL2, CYP1A1, CYP1A2, CYP1B1, DNMT1, DRD1, EGFR, ESR1, FABP4, FLT3, HSPA1A, HTR1B, IGF1R, INSR, KDR, KIT, MMP2, MMP9, NR3C1, OPRD1, OPRK1, OPRM1, PDE3A, PDE3B, PIK3CA, PRKCB, PRKCD, PRKCE, PTGS2, RORC, SMAD3, SRC, TERT, TRPV1 |
12.3158 |
|
[BP] GO:0071310 |
cellular response to organic substance
|
AKR1B1, AKR1C3, ALOX15, ALPL, APEX1, APP, AR, AXL, BCL2, CYP1A1, CYP1B1, DNMT1, DRD1, EGFR, ESR1, FABP4, FLT3, HTR1B, IGF1R, INSR, KDR, KIT, MMP2, NR3C1, OPRD1, OPRK1, OPRM1, PDE3A, PDE3B, PIK3CA, PRKCB, PRKCD, PRKCE, PTGS2, RORC, SMAD3, SRC, TRPV1 |
12.1643 |
|
[BP] GO:0043067 |
regulation of programmed cell death
|
ADORA1, AKR1B1, AKR1C3, APEX1, AR, AURKB, AXL, BCL2, CNR1, CSNK2A1, CYP1B1, EGFR, ESR1, F3, FLT3, GLO1, HCAR2, HSPA1A, HTR2B, IGF1R, KDR, KIT, MET, MIF, MMP9, PDE3A, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCD, PRKCG, PTGS2, PTPN1, SIGMAR1, SMAD3, SRC, TEK, TERT, TOP2A, TRPV1, XDH |
11.9964 |
|
[BP] GO:0048584 |
positive regulation of response to stimulus
|
ADORA1, AKR1B1, AKR1C3, ALOX15, APP, AR, AXL, BCL2, CNR1, CSNK2A1, CYP1B1, DRD2, EGFR, ESRRA, F10, F3, FABP4, FLT3, GPR35, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, INSR, KDR, KIT, MET, MIF, MMP12, MMP2, MMP9, OPRK1, OPRM1, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
11.9053 |
|
[BP] GO:0042127 |
regulation of cell proliferation
|
ADORA1, ADORA3, AKR1B1, AKR1C3, APP, AR, BCL2, CDC25B, CSNK2A1, CYP1B1, DNMT1, DRD2, EGFR, ESR1, ESRRA, F3, FABP3, FLT3, HSPA1A, HTR1A, HTR1B, HTR2A, HTR2B, IGF1R, INSR, KDR, KIT, MIF, MMP12, MMP2, MMP9, NUAK1, OPRM1, PGR, PIM1, PRKCA, PTGS1, PTGS2, SMAD3, SRC, TEK, TERT, XDH |
11.6624 |
|
[BP] GO:0050896 |
response to stimulus
|
ABCB1, ACHE, ADORA1, ADORA3, AKR1B1, AKR1C3, ALOX15, ALPL, APEX1, APP, AR, AURKB, AXL, BCL2, CA2, CA6, CA9, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DNMT1, DRD1, DRD2, EGFR, ESR1, ESRRA, F10, F3, FABP3, FABP4, FLT3, HSD11B2, HSD17B2, HSPA1A, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR2C, HTR5A, IGF1R, INSR, KDR, KIT, MIF, MMP12, MMP2, MMP9, NR3C1, NUAK1, OPRD1, OPRK1, OPRM1, PDE3A, PDE3B, PIK3CA, PIK3CB, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TOP2A, TRPV1, TYR |
11.6559 |
|
[BP] GO:0044281 |
small molecule metabolic process
|
AKR1B1, AKR1B10, AKR1C3, ALOX15, ALOX5, AOX1, APP, CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CBR1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, FABP3, FUT7, GLO1, HSPA1A, HTR2B, HTR2C, MIF, PDE10A, PDE3A, PDE3B, PIK3CA, PIM1, PPARA, PTGS1, PTGS2, SOAT1, SOAT2, TYR, XDH |
11.6559 |
|
[BP] GO:0010941 |
regulation of cell death
|
ADORA1, AKR1B1, AKR1C3, APEX1, AR, AURKB, AXL, BCL2, CNR1, CSNK2A1, CYP1B1, EGFR, ESR1, F3, FLT3, GLO1, HCAR2, HSPA1A, HTR2B, IGF1R, KDR, KIT, MET, MIF, MMP9, PDE3A, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCD, PRKCG, PTGS2, PTPN1, SIGMAR1, SMAD3, SRC, TEK, TERT, TOP2A, TRPV1, XDH |
11.6454 |
|
[BP] GO:0033993 |
response to lipid
|
AKR1C3, ALPL, AR, AXL, BCL2, CA2, CA9, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, EGFR, ESR1, ESRRA, FABP3, FLT3, HSD11B2, HSD17B2, HTR1B, HTR5A, NR3C1, OPRK1, OPRM1, PRKCE, PTGS2, RORC, SRC, TYR |
11.3414 |
|
[BP] GO:0048518 |
positive regulation of biological process
|
ABCB1, ACHE, ADORA1, AKR1B1, AKR1C3, ALOX15, APEX1, APP, AR, AURKB, AXL, BCL2, CA2, CA7, CDC25B, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, GPR35, HCAR2, HSPA1A, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, KIT, MET, MIF, MMP1, MMP12, MMP2, MMP9, NR3C1, OPRD1, OPRK1, OPRM1, PDE3A, PGR, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SOAT1, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
11.3119 |
|
[BP] GO:0032879 |
regulation of localization
|
ABCB1, ACHE, ADORA1, ADORA3, ALOX15, APEX1, APP, AR, AXL, BCL2, CA2, CA7, CNR1, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, EGFR, F10, F3, GPR35, HCAR2, HSPA1A, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, OPRD1, OPRK1, OPRM1, PIK3CB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TRPV1 |
11.2255 |
|
[BP] GO:0008152 |
metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, AKR1C3, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CBR1, CDC25B, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, FUT7, GLO1, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR1B, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, MIF, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NR3C2, NUAK1, PDE10A, PDE3A, PDE3B, PGR, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SENP6, SLC22A2, SMAD3, SOAT1, SOAT2, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
11.1533 |
|
[BP] GO:0042981 |
regulation of apoptotic process
|
ADORA1, AKR1B1, AKR1C3, APEX1, AR, AURKB, AXL, BCL2, CNR1, CSNK2A1, CYP1B1, EGFR, ESR1, F3, FLT3, GLO1, HCAR2, HSPA1A, HTR2B, IGF1R, KDR, MIF, MMP9, PDE3A, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCD, PRKCG, PTGS2, PTPN1, SIGMAR1, SMAD3, SRC, TEK, TERT, TOP2A, TRPV1, XDH |
10.796 |
|
[BP] GO:0010243 |
response to organonitrogen compound
|
AKR1B1, APEX1, APP, CNR1, CNR2, DNMT1, DRD1, DRD2, EGFR, FABP3, FLT3, HSD11B2, HTR1B, IGF1R, INSR, MMP2, OPRK1, OPRM1, PDE3A, PDE3B, PPARA, PRKCD, PRKCE, PRKCG, PTGS2, SRC, TEK, TRPV1, TYR |
10.796 |
|
[BP] GO:0019748 |
secondary metabolic process
|
AKR1B1, AKR1B10, AKR1C3, BCL2, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, TYR |
10.7754 |
|
[BP] GO:0007165 |
signal transduction
|
ADORA1, ADORA3, AKR1B1, AKR1C3, APP, AR, AXL, BCL2, CA1, CA2, CNR1, CNR2, CSNK2A1, CYP1B1, DNMT1, DRD1, DRD2, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, HCAR2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MET, MIF, MMP2, MMP9, NR3C1, NR3C2, NUAK1, OPRD1, OPRK1, OPRM1, PDE10A, PDE3A, PDE3B, PGR, PIK3CA, PIK3CB, PIM1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, RORC, SIGMAR1, SMAD3, SRC, TEK, TNKS, TNKS2, TRPV1 |
10.5907 |
|
[BP] GO:0051173 |
positive regulation of nitrogen compound metabolic process
|
ADORA1, ALOX15, APP, AR, AURKB, BCL2, CDC25B, CSNK2A1, DNMT1, DRD1, DRD2, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, NR3C1, OPRD1, OPRK1, OPRM1, PGR, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SOAT1, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
10.5663 |
|
[BP] GO:0010562 |
positive regulation of phosphorus metabolic process
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, DRD1, DRD2, EGFR, ESRRB, FABP3, FLT3, HTR2A, HTR2B, HTR2C, INSR, KDR, KIT, MIF, MMP9, OPRD1, OPRK1, OPRM1, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
10.5273 |
|
[BP] GO:0045937 |
positive regulation of phosphate metabolic process
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, DRD1, DRD2, EGFR, ESRRB, FABP3, FLT3, HTR2A, HTR2B, HTR2C, INSR, KDR, KIT, MIF, MMP9, OPRD1, OPRK1, OPRM1, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
10.5273 |
|
[BP] GO:0019369 |
arachidonic acid metabolic process
|
AKR1C3, ALOX15, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, PTGS1, PTGS2 |
10.519 |
|
[BP] GO:0031325 |
positive regulation of cellular metabolic process
|
ADORA1, AKR1C3, ALOX15, APP, AR, AURKB, BCL2, CDC25B, DNMT1, DRD1, DRD2, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FLT3, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, NR3C1, OPRD1, OPRK1, OPRM1, PGR, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SOAT1, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
10.5108 |
|
[BP] GO:0010817 |
regulation of hormone levels
|
ACHE, ADORA1, AKR1B1, AKR1C3, CNR1, CYP19A1, CYP1A1, CYP1B1, CYP3A4, DRD2, EGFR, ESR1, HCAR2, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HTR1A, HTR2A, HTR2C, OPRK1, PRKCA, PRKCE, SLC22A1 |
10.5108 |
|
[BP] GO:0032501 |
multicellular organismal process
|
ADORA1, AKR1B1, AKR1B10, AKR1C3, ALOX15, ALOX5, ALPL, APP, AR, AXL, BCL2, CNR1, CNR2, CYP19A1, CYP1A2, CYP1B1, DRD1, DRD2, DUSP3, EGFR, ESR1, ESRRB, F10, F3, FABP4, HSD11B2, HSD17B2, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR2C, HTR7, IGF1R, INSR, KIT, MET, MMP1, MMP12, MMP2, MMP9, OPRD1, OPRK1, OPRM1, PDE3A, PIK3CA, PIM1, PPARA, PRKCD, PRKCG, PTGS2, RORC, SMAD3, SOAT1, SOAT2, SRC, TEK, TNKS2, TRPV1, TYR |
10.4849 |
|
[BP] GO:0008202 |
steroid metabolic process
|
AKR1B1, AKR1B10, AKR1C3, APP, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP2D6, CYP3A4, ESR1, HSD11B1, HSD11B2, HSD17B1, HSD17B2, SOAT1, SOAT2 |
10.4836 |
|
[BP] GO:0033559 |
unsaturated fatty acid metabolic process
|
AKR1C3, ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, MIF, PTGS1, PTGS2 |
10.3887 |
|
[BP] GO:0048523 |
negative regulation of cellular process
|
ACHE, ADORA1, ADORA3, AKR1B1, AKR1C3, APEX1, APP, AR, AURKB, AXL, BCL2, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, CYP2D6, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, GLO1, GPR35, HSPA1A, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IGF1R, KDR, KIT, MET, MIF, MMP12, MMP9, NR3C1, OPRD1, OPRK1, OPRM1, PDE3A, PDE3B, PIK3CA, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, PTPRS, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
10.373 |
|
[BP] GO:0007187 |
None
|
ADORA1, CNR1, CNR2, DRD1, DRD2, HTR1A, HTR1B, HTR1D, HTR1E, HTR4, HTR5A, HTR6, HTR7, OPRD1, OPRK1, OPRM1 |
10.3298 |
|
[BP] GO:0032844 |
regulation of homeostatic process
|
ADORA1, AURKB, BCL2, CA2, CA7, CNR1, DRD1, DRD2, EGFR, HCAR2, HTR2A, HTR2B, HTR2C, KDR, MIF, OPRK1, PIK3CB, PRKCE, PTGS2, SRC, TNKS, TNKS2, TRPV1 |
10.2749 |
|
[BP] GO:0044237 |
cellular metabolic process
|
ACHE, AKR1B1, AKR1B10, AKR1C3, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CBR1, CDC25B, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, FABP3, FABP4, FLT3, FUT7, GLO1, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR1B, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, MIF, MMP1, MMP2, NQO2, NR3C1, NR3C2, NUAK1, PDE10A, PDE3A, PDE3B, PGR, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SENP6, SLC22A2, SMAD3, SOAT1, SOAT2, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
10.1191 |
|
[BP] GO:0048583 |
regulation of response to stimulus
|
ABCB1, ADORA1, AKR1B1, AKR1C3, ALOX15, APP, AR, AURKB, AXL, BCL2, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, F10, F3, FABP4, FLT3, GPR35, HSPA1A, HTR1B, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP2, MMP9, NUAK1, OPRK1, OPRM1, PDE10A, PDE3B, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
10.1031 |
|
[BP] GO:1901698 |
response to nitrogen compound
|
AKR1B1, APEX1, APP, CNR1, CNR2, DNMT1, DRD1, DRD2, EGFR, FABP3, FLT3, HSD11B2, HTR1B, IGF1R, INSR, MMP2, OPRK1, OPRM1, PDE3A, PDE3B, PPARA, PRKCD, PRKCE, PRKCG, PTGS2, SRC, TEK, TRPV1, TYR |
10.099 |
|
[BP] GO:0006690 |
icosanoid metabolic process
|
AKR1C3, ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, MIF, PTGS1, PTGS2 |
10.0409 |
|
[BP] GO:0015701 |
bicarbonate transport
|
CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9 |
9.99841 |
|
[BP] GO:0006796 |
phosphate-containing compound metabolic process
|
ACHE, ALOX15, ALPL, APEX1, APP, AURKB, AXL, BCL2, CDC25B, CSNK2A1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, FLT3, HSPA1A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, NUAK1, PDE10A, PDE3A, PDE3B, PIK3CA, PIK3CB, PIM1, POLB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, PTPRS, SRC, TEK, TNKS, XDH |
9.84375 |
|
[BP] GO:0048519 |
negative regulation of biological process
|
ACHE, ADORA1, ADORA3, AKR1B1, AKR1C3, ALOX15, APEX1, APP, AR, AURKB, AXL, BCL2, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, CYP2D6, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, GLO1, GPR35, HCAR2, HSPA1A, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IGF1R, KDR, KIT, MET, MIF, MMP12, MMP9, NR3C1, OPRD1, OPRK1, OPRM1, PDE3A, PDE3B, PGR, PIK3CA, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, PTPRS, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
9.82426 |
|
[BP] GO:0009893 |
positive regulation of metabolic process
|
ADORA1, AKR1C3, ALOX15, APP, AR, AURKB, BCL2, CDC25B, CSNK2A1, DNMT1, DRD1, DRD2, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FLT3, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, NR3C1, OPRD1, OPRK1, OPRM1, PGR, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SOAT1, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
9.7615 |
|
[BP] GO:0043410 |
positive regulation of MAPK cascade
|
ADORA1, ALOX15, APP, AR, DRD2, EGFR, FLT3, HTR2A, HTR2B, HTR2C, INSR, KDR, KIT, MIF, OPRK1, OPRM1, PIK3CB, PRKCA, PRKCE, PTPN1, SRC, TEK, XDH |
9.66815 |
|
[BP] GO:0042327 |
positive regulation of phosphorylation
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, DRD2, EGFR, ESRRB, FLT3, HTR2A, HTR2B, HTR2C, INSR, KDR, KIT, MIF, MMP9, OPRD1, OPRK1, OPRM1, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
9.6502 |
|
[BP] GO:0019220 |
regulation of phosphate metabolic process
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, DRD1, DRD2, DUSP3, EGFR, ESRRB, FABP3, FABP4, FLT3, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MIF, MMP9, NUAK1, OPRD1, OPRK1, OPRM1, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
9.6502 |
|
[BP] GO:0051716 |
cellular response to stimulus
|
AKR1B1, AKR1C3, ALOX15, ALPL, APEX1, APP, AR, AURKB, AXL, BCL2, CA2, CA9, CYP1A1, CYP1A2, CYP1B1, DNMT1, DRD1, EGFR, ESR1, FABP4, FLT3, HSPA1A, HTR1B, IGF1R, INSR, KDR, KIT, MIF, MMP2, MMP9, NR3C1, NUAK1, OPRD1, OPRK1, OPRM1, PDE3A, PDE3B, PIK3CA, POLA1, POLB, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, RORC, SMAD3, SRC, TERT, TOP2A, TRPV1 |
9.59431 |
|
[BP] GO:0051174 |
regulation of phosphorus metabolic process
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, DRD1, DRD2, DUSP3, EGFR, ESRRB, FABP3, FABP4, FLT3, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MIF, MMP9, NUAK1, OPRD1, OPRK1, OPRM1, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
9.55261 |
|
[BP] GO:0043069 |
negative regulation of programmed cell death
|
ADORA1, AKR1B1, AR, AURKB, AXL, BCL2, CSNK2A1, EGFR, GLO1, HSPA1A, HTR2B, IGF1R, KDR, KIT, MET, MIF, MMP9, PDE3A, PIK3CA, PIM1, PRKCA, PRKCD, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT |
9.55207 |
|
[BP] GO:0009628 |
response to abiotic stimulus
|
ADORA1, AKR1B1, APP, AURKB, BCL2, CA2, CYP1A1, DRD1, DRD2, EGFR, HSD11B2, HSPA1A, HTR1B, HTR2A, HTR2B, KIT, MMP2, OPRD1, OPRK1, OPRM1, POLB, PPARA, PRKCB, PRKCE, PTGS2, SMAD3, SRC, TEK, TERT, TRPV1, TYR |
9.52118 |
|
[BP] GO:1901701 |
cellular response to oxygen-containing compound
|
AKR1B1, AKR1C3, APEX1, APP, AR, AXL, CYP1B1, DNMT1, DRD1, EGFR, ESR1, IGF1R, INSR, MMP2, MMP9, NR3C1, OPRK1, PDE3A, PDE3B, PIK3CA, PRKCB, PRKCD, PRKCE, PTGS2, RORC, SRC, TRPV1 |
9.44342 |
|
[BP] GO:0001934 |
positive regulation of protein phosphorylation
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, DRD2, EGFR, FLT3, HTR2A, HTR2B, HTR2C, INSR, KDR, KIT, MIF, MMP9, OPRD1, OPRK1, OPRM1, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
9.41568 |
|
[BP] GO:0051049 |
regulation of transport
|
ABCB1, ACHE, ADORA1, ALOX15, APP, AXL, BCL2, CA2, CA7, CNR1, CYP19A1, DRD1, DRD2, EGFR, GPR35, HCAR2, HSPA1A, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, INSR, MIF, MMP12, MMP9, OPRD1, OPRK1, OPRM1, PIK3CB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TERT, TRPV1 |
9.40238 |
|
[BP] GO:0010604 |
positive regulation of macromolecule metabolic process
|
ADORA1, ALOX15, APP, AR, AURKB, BCL2, CDC25B, CSNK2A1, DNMT1, DRD1, DRD2, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, NR3C1, OPRD1, OPRK1, OPRM1, PGR, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SOAT1, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
9.40238 |
|
[BP] GO:0060548 |
negative regulation of cell death
|
ADORA1, AKR1B1, AR, AURKB, AXL, BCL2, CSNK2A1, EGFR, GLO1, HSPA1A, HTR2B, IGF1R, KDR, KIT, MET, MIF, MMP9, PDE3A, PIK3CA, PIM1, PPARA, PRKCA, PRKCD, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT |
9.37717 |
|
[BP] GO:0006730 |
one-carbon metabolic process
|
CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9 |
9.30727 |
|
[BP] GO:0009966 |
regulation of signal transduction
|
ADORA1, AKR1B1, AKR1C3, ALOX15, APP, AR, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, F10, F3, FLT3, GPR35, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, NUAK1, OPRK1, OPRM1, PDE10A, PDE3B, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
9.27028 |
|
[BP] GO:0006793 |
phosphorus metabolic process
|
ACHE, ALOX15, ALPL, APEX1, APP, AURKB, AXL, BCL2, CDC25B, CSNK2A1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, FLT3, HSPA1A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, NUAK1, PDE10A, PDE3A, PDE3B, PIK3CA, PIK3CB, PIM1, POLB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, PTPRS, SRC, TEK, TNKS, XDH |
9.26047 |
|
[BP] GO:0044255 |
cellular lipid metabolic process
|
ACHE, AKR1B10, AKR1C3, ALOX15, ALOX5, CBR1, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DRD2, EGFR, FABP3, FABP4, FUT7, KIT, MET, MIF, PDE3A, PIK3CA, PIK3CB, PPARA, PTGS1, PTGS2, SOAT1, SOAT2 |
9.25159 |
|
[BP] GO:0043408 |
regulation of MAPK cascade
|
ADORA1, ALOX15, APP, AR, DRD2, DUSP3, EGFR, FLT3, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MIF, OPRK1, OPRM1, PIK3CB, PRKCA, PRKCD, PRKCE, PTPN1, SRC, TEK, XDH |
9.17422 |
|
[BP] GO:0007193 |
None
|
ADORA1, DRD2, HTR1A, HTR1B, HTR1D, HTR1E, HTR5A, HTR7, OPRD1, OPRK1, OPRM1 |
9.04698 |
|
[BP] GO:0009636 |
response to toxic substance
|
AKR1B1, ALPL, APEX1, AXL, BCL2, CNR1, CNR2, CYP1A1, CYP1B1, DRD1, DRD2, HTR1B, HTR1D, KDR, OPRD1, OPRK1, POLB, PRKCD, PRKCE, SRC |
9.01381 |
|
[BP] GO:0042592 |
homeostatic process
|
ADORA1, AKR1B1, APEX1, APP, AXL, BCL2, CA12, CA2, CA7, CNR1, DRD1, DRD2, EGFR, ESR1, FABP3, FABP4, FLT3, GPR35, HTR2A, HTR2B, HTR2C, INSR, MET, PIK3CA, PIK3CB, POLA1, POLB, PRKCB, PRKCE, SMAD3, SOAT1, SOAT2, SRC, TERT, TRPV1 |
8.92011 |
|
[BP] GO:0007186 |
G-protein coupled receptor signaling pathway
|
ADORA1, ADORA3, AKR1C3, APP, CA2, CNR1, CNR2, DRD1, DRD2, ESR1, GPR35, HCAR2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, INSR, OPRD1, OPRK1, OPRM1, PDE10A, PDE3A, PDE3B, PIK3CA, PIK3CB, SIGMAR1, SRC |
8.8884 |
|
[BP] GO:0071495 |
cellular response to endogenous stimulus
|
AKR1B1, AKR1C3, APEX1, APP, AR, DNMT1, DRD1, EGFR, ESR1, FLT3, HTR1B, IGF1R, INSR, KIT, MMP2, NR3C1, OPRM1, PDE3A, PDE3B, PRKCD, PRKCE, PTGS2, SMAD3, SRC, TRPV1 |
8.86192 |
|
[BP] GO:0019216 |
regulation of lipid metabolic process
|
ADORA1, AKR1C3, CNR1, CYP1A1, FABP3, FLT3, HCAR2, HTR2A, HTR2B, HTR2C, KIT, PDE3B, PPARA, PRKCD, PRKCE, PTGS2, RORC, SRC, TEK |
8.86192 |
|
[BP] GO:0010035 |
response to inorganic substance
|
AKR1B1, AKR1C3, ALOX15, APEX1, APP, AXL, BCL2, CA2, CYP1A1, CYP1A2, CYP1B1, DRD2, EGFR, FABP4, KDR, KIT, MMP9, PRKCD, PTGS2, SRC, TERT |
8.85022 |
|
[BP] GO:0051247 |
positive regulation of protein metabolic process
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, CSNK2A1, DNMT1, DRD2, DYRK1A, EGFR, ESR1, F3, FLT3, HSPA1A, HTR2A, HTR2B, HTR2C, INSR, KDR, KIT, MIF, MMP9, OPRD1, OPRK1, OPRM1, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SOAT1, SRC, TEK, XDH |
8.76042 |
|
[BP] GO:0008284 |
positive regulation of cell proliferation
|
AKR1B1, AKR1C3, AR, BCL2, CDC25B, CSNK2A1, DRD2, EGFR, ESR1, F3, FLT3, HTR1A, HTR1B, HTR2A, HTR2B, IGF1R, INSR, KDR, KIT, MIF, MMP12, MMP2, MMP9, PIM1, PRKCA, PTGS2, TEK, TERT |
8.7064 |
|
[BP] GO:0048511 |
rhythmic process
|
AXL, BCL2, CSNK2A1, DRD2, DYRK1A, EGFR, ESR1, HTR7, KIT, OPRK1, OPRM1, PGR, PPARA, PRKCG, RORC, SRC, TOP2A |
8.65428 |
|
[BP] GO:0040012 |
regulation of locomotion
|
ADORA1, ADORA3, APEX1, APP, BCL2, CYP19A1, CYP1B1, DRD1, DRD2, EGFR, F10, F3, HTR1D, IGF1R, INSR, KDR, KIT, MET, MIF, MMP9, OPRK1, PRKCA, PRKCE, PTGS2, SMAD3, SRC, TEK, TERT |
8.64503 |
|
[BP] GO:1903727 |
positive regulation of phospholipid metabolic process
|
FABP3, FLT3, HTR2A, HTR2B, HTR2C, KIT, PRKCD, SRC, TEK |
8.63878 |
|
[BP] GO:0009892 |
negative regulation of metabolic process
|
ADORA1, AKR1C3, APEX1, APP, AR, AURKB, BCL2, CNR1, CNR2, CSNK2A1, CYP2D6, DNMT1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, FABP4, HCAR2, HSPA1A, HTR1B, HTR1E, HTR2B, IGF1R, KDR, MET, MIF, MMP12, MMP9, NR3C1, OPRD1, OPRM1, PDE3B, PGR, PIK3CA, PPARA, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TRPV1, XDH |
8.5564 |
|
[BP] GO:0030334 |
regulation of cell migration
|
ADORA1, ADORA3, APEX1, APP, BCL2, CYP19A1, CYP1B1, DRD1, DRD2, EGFR, F10, F3, IGF1R, INSR, KDR, KIT, MET, MIF, MMP9, PRKCA, PRKCE, PTGS2, SMAD3, SRC, TEK, TERT |
8.52704 |
|
[BP] GO:0042325 |
regulation of phosphorylation
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, DRD1, DRD2, DUSP3, EGFR, ESRRB, FABP4, FLT3, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MIF, MMP9, OPRD1, OPRK1, OPRM1, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
8.40862 |
|
[BP] GO:0032502 |
developmental process
|
ACHE, ADORA1, AKR1B1, AKR1C3, ALOX15, ALPL, APEX1, APP, AR, AURKB, AXL, BCL2, CA2, CA9, CBR1, CDC25B, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESRRA, ESRRB, FABP4, FLT3, FUT7, GLO1, HSD11B1, HSD17B2, HTR2A, HTR2B, HTR5A, INSR, KDR, KIT, MET, MIF, MMP2, MMP9, PDE3A, PDE3B, PGR, PIK3CA, PIK3CB, PIM1, POLB, PPARA, PRKCA, PRKCD, PTGS2, PTPRS, RORC, SIGMAR1, SMAD3, SOAT1, SOAT2, SRC, TEK, TERT, TNKS2, TOP2A, TYR |
8.40862 |
|
[BP] GO:0043066 |
negative regulation of apoptotic process
|
ADORA1, AKR1B1, AR, AURKB, AXL, BCL2, CSNK2A1, EGFR, GLO1, HSPA1A, HTR2B, IGF1R, KDR, MIF, MMP9, PDE3A, PIK3CA, PIM1, PRKCA, PRKCD, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT |
8.32308 |
|
[BP] GO:0010648 |
negative regulation of cell communication
|
ACHE, ADORA1, AR, BCL2, CNR2, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, GPR35, HSPA1A, HTR1B, HTR2A, IGF1R, MET, MIF, MMP12, MMP9, OPRK1, OPRM1, PDE3B, PRKCB, PRKCD, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TERT, XDH |
8.30791 |
|
[BP] GO:0031401 |
positive regulation of protein modification process
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, DNMT1, DRD2, DYRK1A, EGFR, FLT3, HTR2A, HTR2B, HTR2C, INSR, KDR, KIT, MIF, MMP9, OPRD1, OPRK1, OPRM1, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
8.30739 |
|
[BP] GO:0031399 |
regulation of protein modification process
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, FABP4, FLT3, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MIF, MMP9, NUAK1, OPRD1, OPRK1, OPRM1, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SRC, TEK, XDH |
8.28946 |
|
[BP] GO:0023057 |
negative regulation of signaling
|
ACHE, ADORA1, AR, BCL2, CNR2, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, GPR35, HSPA1A, HTR1B, HTR2A, IGF1R, MET, MIF, MMP12, MMP9, OPRK1, OPRM1, PDE3B, PRKCB, PRKCD, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TERT, XDH |
8.28254 |
|
[BP] GO:0032270 |
positive regulation of cellular protein metabolic process
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, DNMT1, DRD2, DYRK1A, EGFR, ESR1, F3, FLT3, HSPA1A, HTR2A, HTR2B, HTR2C, INSR, KDR, KIT, MIF, MMP9, OPRD1, OPRK1, OPRM1, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
8.21975 |
|
[BP] GO:0071407 |
cellular response to organic cyclic compound
|
AKR1C3, ALPL, APEX1, APP, AR, CYP1A1, CYP1B1, DRD1, EGFR, ESR1, FLT3, NR3C1, OPRM1, PDE3A, PTGS2, RORC, SRC, TRPV1 |
8.216 |
|
[BP] GO:0032228 |
regulation of synaptic transmission, GABAergic
|
ADORA1, CA2, CA7, CNR1, CNR2, DRD2, HTR1B, PRKCE |
8.20327 |
|
[BP] GO:0001932 |
regulation of protein phosphorylation
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, DRD1, DRD2, DUSP3, EGFR, FABP4, FLT3, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MIF, MMP9, OPRD1, OPRK1, OPRM1, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TEK, XDH |
8.16861 |
|
[BP] GO:0045834 |
positive regulation of lipid metabolic process
|
FABP3, FLT3, HTR2A, HTR2B, HTR2C, KIT, PPARA, PRKCD, PRKCE, PTGS2, SRC, TEK |
8.06998 |
|
[BP] GO:1901568 |
fatty acid derivative metabolic process
|
AKR1C3, ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, MIF, PTGS1, PTGS2 |
8.05943 |
|
[BP] GO:0003018 |
None
|
ADORA1, DRD1, EGFR, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PDE3A, PTGS2, SRC, TEK |
8.05943 |
|
[BP] GO:0007188 |
None
|
ADORA1, CNR1, DRD1, DRD2, HTR1A, HTR1B, HTR1D, HTR1E, HTR5A, HTR7, OPRD1, OPRK1, OPRM1 |
8.02739 |
|
[BP] GO:2000145 |
regulation of cell motility
|
ADORA1, ADORA3, APEX1, APP, BCL2, CYP19A1, CYP1B1, DRD1, DRD2, EGFR, F10, F3, IGF1R, INSR, KDR, KIT, MET, MIF, MMP9, PRKCA, PRKCE, PTGS2, SMAD3, SRC, TEK, TERT |
7.97916 |
|
[BP] GO:0001676 |
long-chain fatty acid metabolic process
|
AKR1C3, ALOX15, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, PTGS1, PTGS2 |
7.83823 |
|
[BP] GO:0007610 |
None
|
APP, BCL2, CNR1, DRD1, DRD2, EGFR, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, INSR, KIT, OPRD1, OPRK1, OPRM1, PPARA, PRKCE, PRKCG, PTGS2, TRPV1 |
7.68815 |
|
[BP] GO:0040017 |
positive regulation of locomotion
|
APP, BCL2, DRD1, EGFR, F10, F3, IGF1R, INSR, KDR, KIT, MET, MMP9, OPRK1, PRKCA, PRKCE, PTGS2, SMAD3, SRC, TEK, TERT |
7.6338 |
|
[BP] GO:0070482 |
response to oxygen levels
|
ADORA1, BCL2, CYP1A1, DRD2, HSD11B2, MMP2, OPRD1, POLB, PPARA, PRKCB, PRKCE, PTGS2, SMAD3, SRC, TEK, TERT |
7.5763 |
|
[BP] GO:0080134 |
regulation of response to stress
|
ABCB1, ADORA1, APP, CNR1, CNR2, CYP19A1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, F3, FABP4, HSPA1A, IGF1R, MET, MIF, MMP12, MMP2, NUAK1, OPRK1, PPARA, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TEK, TERT, XDH |
7.52517 |
|
[BP] GO:0030335 |
positive regulation of cell migration
|
APP, BCL2, DRD1, EGFR, F10, F3, IGF1R, INSR, KDR, KIT, MET, MMP9, PRKCA, PRKCE, PTGS2, SMAD3, SRC, TEK, TERT |
7.5129 |
|
[BP] GO:0006468 |
protein phosphorylation
|
APP, AURKB, AXL, BCL2, CDC25B, CSNK2A1, DRD1, DYRK1A, EGFR, FLT3, HTR2B, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TNKS |
7.50409 |
|
[BP] GO:0097756 |
None
|
ADORA1, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PTGS2 |
7.50113 |
|
[BP] GO:0051896 |
regulation of protein kinase B signaling
|
AKR1C3, AXL, DRD2, EGFR, F10, F3, INSR, KIT, MET, PIK3CA, PIK3CB, SRC, TEK, XDH |
7.49062 |
|
[BP] GO:0048878 |
chemical homeostasis
|
AKR1B1, APP, BCL2, CA12, CA2, CA7, CNR1, DRD1, DRD2, EGFR, ESR1, FABP3, FABP4, GPR35, HTR2A, HTR2B, HTR2C, INSR, MET, PIK3CA, PIK3CB, PRKCB, PRKCE, SMAD3, SOAT1, SOAT2, TRPV1 |
7.43431 |
|
[BP] GO:0050804 |
modulation of chemical synaptic transmission
|
ACHE, ADORA1, APP, BACE1, CA2, CA7, CNR1, CNR2, DRD1, DRD2, EGFR, HTR1B, HTR2A, KIT, PRKCE, PTGS2 |
7.38727 |
|
[BP] GO:0099177 |
regulation of trans-synaptic signaling
|
ACHE, ADORA1, APP, BACE1, CA2, CA7, CNR1, CNR2, DRD1, DRD2, EGFR, HTR1B, HTR2A, KIT, PRKCE, PTGS2 |
7.38727 |
|
[BP] GO:0001666 |
response to hypoxia
|
ADORA1, BCL2, CYP1A1, DRD2, HSD11B2, MMP2, OPRD1, PPARA, PRKCB, PRKCE, PTGS2, SMAD3, SRC, TEK, TERT |
7.33309 |
|
[BP] GO:0032845 |
None
|
ADORA1, BCL2, DRD2, HTR2A, HTR2B, HTR2C, MIF, PRKCE, SRC, TNKS, TNKS2, TRPV1 |
7.32668 |
|
[BP] GO:2000147 |
positive regulation of cell motility
|
APP, BCL2, DRD1, EGFR, F10, F3, IGF1R, INSR, KDR, KIT, MET, MMP9, PRKCA, PRKCE, PTGS2, SMAD3, SRC, TEK, TERT |
7.28247 |
|
[BP] GO:0044238 |
primary metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, AKR1C3, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BACE1, BCL2, CBR1, CDC25B, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, FUT7, GLO1, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, MIF, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, NUAK1, PDE10A, PDE3A, PDE3B, PGR, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SENP6, SMAD3, SOAT1, SOAT2, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
7.28042 |
|
[BP] GO:0051270 |
regulation of cellular component movement
|
ADORA1, ADORA3, APEX1, APP, BCL2, CYP19A1, CYP1B1, DRD1, DRD2, EGFR, F10, F3, IGF1R, INSR, KDR, KIT, MET, MIF, MMP9, PRKCA, PRKCE, PTGS2, SMAD3, SRC, TEK, TERT |
7.26091 |
|
[BP] GO:0036293 |
response to decreased oxygen levels
|
ADORA1, BCL2, CYP1A1, DRD2, HSD11B2, MMP2, OPRD1, PPARA, PRKCB, PRKCE, PTGS2, SMAD3, SRC, TEK, TERT |
7.16921 |
|
[BP] GO:0051272 |
positive regulation of cellular component movement
|
APP, BCL2, DRD1, EGFR, F10, F3, IGF1R, INSR, KDR, KIT, MET, MMP9, PRKCA, PRKCE, PTGS2, SMAD3, SRC, TEK, TERT |
7.09588 |
|
[BP] GO:0015711 |
organic anion transport
|
ABCB1, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, DRD2, FABP3, PPARA, SLC22A1, SLC22A2, SLC22A3, TRPV1 |
7.07924 |
|
[BP] GO:0051897 |
positive regulation of protein kinase B signaling
|
AKR1C3, AXL, EGFR, F10, F3, INSR, KIT, MET, PIK3CA, PIK3CB, SRC, TEK |
7.07902 |
|
[BP] GO:0070372 |
regulation of ERK1 and ERK2 cascade
|
ALOX15, APP, DRD2, DUSP3, EGFR, HTR2A, HTR2B, HTR2C, KDR, MIF, OPRM1, PRKCA, PTPN1, SRC, TEK |
7.02454 |
|
[BP] GO:0071704 |
organic substance metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, AKR1C3, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BACE1, BCL2, CBR1, CDC25B, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, FUT7, GLO1, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR1B, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, MIF, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, NUAK1, PDE10A, PDE3A, PDE3B, PGR, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SENP6, SMAD3, SOAT1, SOAT2, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
6.99275 |
|
[BP] GO:0003008 |
None
|
ADORA1, AKR1B1, AKR1C3, APP, BCL2, CNR1, CNR2, CYP1B1, DRD1, DRD2, EGFR, HSD11B2, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, INSR, KIT, OPRD1, OPRK1, OPRM1, PDE3A, PIK3CA, PRKCG, PTGS2, SOAT2, SRC, TEK, TRPV1, TYR |
6.92009 |
|
[BP] GO:0046777 |
protein autophosphorylation
|
AURKB, CSNK2A1, DYRK1A, EGFR, FLT3, IGF1R, INSR, KDR, KIT, PIM1, PRKCG, SRC, TEK |
6.88637 |
|
[BP] GO:0080090 |
regulation of primary metabolic process
|
ADORA1, ADORA3, AKR1C3, ALOX15, APEX1, APP, AR, AURKB, BCL2, CA9, CDC25B, CNR1, CSNK2A1, CYP1A1, CYP1B1, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GLO1, HCAR2, HSPA1A, HTR1A, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, NR3C1, NR3C2, NUAK1, OPRD1, OPRK1, OPRM1, PDE3B, PGR, PIK3CA, PIK3CB, PIM1, POLA1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SOAT1, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
6.88637 |
|
[BP] GO:0035690 |
cellular response to drug
|
AKR1B1, APEX1, AXL, CYP1B1, DRD1, EGFR, HTR1B, KDR, NR3C1, OPRM1, PRKCD, PRKCE, PTGS2, SRC, TRPV1 |
6.87258 |
|
[BP] GO:0070374 |
positive regulation of ERK1 and ERK2 cascade
|
ALOX15, APP, DRD2, EGFR, HTR2A, HTR2B, HTR2C, KDR, MIF, OPRM1, PRKCA, SRC, TEK |
6.86849 |
|
[BP] GO:0007154 |
None
|
ADORA1, AKR1C3, AR, AXL, BCL2, CNR1, DRD1, DRD2, ESR2, HTR1B, HTR1D, HTR1E, HTR2A, HTR2C, HTR4, HTR6, HTR7, OPRD1, OPRK1, OPRM1, PGR, PRKCG, PTGS2, TEK, TRPV1 |
6.85029 |
|
[BP] GO:0043269 |
regulation of ion transport
|
ABCB1, ADORA1, APP, BCL2, CA2, CA7, CNR1, DRD1, DRD2, GPR35, HTR1A, HTR1B, HTR2A, MIF, MMP9, OPRD1, OPRK1, OPRM1, PRKCD, PRKCE, PTGS2 |
6.84241 |
|
[BP] GO:0006950 |
response to stress
|
ACHE, ADORA1, ADORA3, AKR1B1, AKR1C3, ALOX15, APEX1, APP, AXL, BCL2, CA2, CA9, CNR2, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, EGFR, HSD11B2, HSPA1A, HTR1A, HTR2C, KIT, MIF, MMP2, MMP9, NUAK1, OPRD1, OPRK1, OPRM1, PIK3CA, PIK3CB, POLA1, POLB, PPARA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TOP2A, TRPV1 |
6.83568 |
|
[BP] GO:0065007 |
biological regulation
|
ABCB1, ACHE, ADORA1, ADORA3, AKR1B1, AKR1C3, ALOX15, APEX1, APP, AR, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA2, CA7, CA9, CDC25B, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, CYP3A4, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, GLO1, GPR35, HCAR2, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MET, MIF, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, NUAK1, OPRD1, OPRK1, OPRM1, PDE10A, PDE3A, PDE3B, PGR, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SENP6, SIGMAR1, SLC22A1, SLC22A2, SLC22A3, SMAD3, SOAT1, SOAT2, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
6.81893 |
|
[BP] GO:0019222 |
regulation of metabolic process
|
ACHE, ADORA1, ADORA3, AKR1C3, ALOX15, APEX1, APP, AR, AURKB, BCL2, CA9, CDC25B, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GLO1, HCAR2, HSPA1A, HTR1A, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, NR3C1, NR3C2, NUAK1, OPRD1, OPRK1, OPRM1, PDE3B, PGR, PIK3CA, PIK3CB, PIM1, POLA1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SOAT1, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
6.81893 |
|
[BP] GO:0051239 |
regulation of multicellular organismal process
|
ADORA1, ADORA3, APP, AR, AXL, BCL2, CA2, CNR1, CYP1B1, DRD2, EGFR, ESR1, ESRRA, ESRRB, F3, GPR35, HCAR2, HSPA1A, HTR2A, HTR2B, HTR2C, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, OPRD1, OPRK1, OPRM1, PDE3A, PDE3B, PIK3CA, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPRS, SMAD3, SRC, TEK, TERT, TNKS2, TRPV1, XDH |
6.7439 |
|
[BP] GO:1903725 |
regulation of phospholipid metabolic process
|
FABP3, FLT3, HTR2A, HTR2B, HTR2C, KIT, PRKCD, SRC, TEK |
6.73097 |
|
[BP] GO:0043401 |
steroid hormone mediated signaling pathway
|
AR, ESR1, ESR2, ESRRA, ESRRB, NR3C1, NR3C2, PGR, PPARA, RORC, SRC |
6.72989 |
|
[BP] GO:0003013 |
None
|
ADORA1, DRD1, EGFR, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PDE3A, PTGS2, SRC, TEK |
6.6911 |
|
[BP] GO:0071417 |
cellular response to organonitrogen compound
|
AKR1B1, APEX1, APP, DNMT1, DRD1, EGFR, HTR1B, IGF1R, INSR, MMP2, OPRM1, PDE3A, PDE3B, PRKCD, PTGS2, SRC, TRPV1 |
6.64774 |
|
[BP] GO:0006631 |
fatty acid metabolic process
|
AKR1C3, ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, FABP3, MIF, PPARA, PTGS1, PTGS2 |
6.62853 |
|
[BP] GO:2000021 |
regulation of ion homeostasis
|
ADORA1, BCL2, CA2, CA7, DRD1, DRD2, HTR2A, HTR2B, HTR2C, KDR, PRKCE, SRC, TRPV1 |
6.62345 |
|
[BP] GO:0055114 |
oxidation-reduction process
|
AKR1B1, AKR1B10, AKR1C3, ALOX15, ALOX5, AOX1, APEX1, CBR1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, HSD11B1, HSD11B2, HSD17B1, HSD17B2, NQO2, PTGS1, PTGS2, TYR, XDH |
6.62051 |
|
[BP] GO:0007198 |
None
|
HTR1A, HTR1B, HTR5A, HTR7 |
6.61097 |
|
[BP] GO:0099536 |
None
|
CNR1, DRD1, DRD2, HTR1B, HTR1D, HTR1E, HTR2A, HTR2C, HTR4, HTR6, HTR7, OPRD1, OPRK1, OPRM1, PRKCG |
6.58018 |
|
[BP] GO:0099537 |
None
|
CNR1, DRD1, DRD2, HTR1B, HTR1D, HTR1E, HTR2A, HTR2C, HTR4, HTR6, HTR7, OPRD1, OPRK1, OPRM1, PRKCG |
6.58018 |
|
[BP] GO:0065009 |
regulation of molecular function
|
ABCB1, ADORA1, ADORA3, APP, AR, AURKB, BCL2, CDC25B, CNR1, CNR2, CSNK2A1, CYP1B1, CYP2D6, DRD1, DRD2, DUSP3, EGFR, ESR1, ESR2, F3, FABP4, FLT3, GPR35, HSPA1A, HTR2A, HTR2B, IGF1R, INSR, KIT, MET, MIF, MMP9, NUAK1, OPRD1, OPRM1, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, TRPV1, XDH |
6.5174 |
|
[BP] GO:0051240 |
positive regulation of multicellular organismal process
|
APP, AR, AXL, BCL2, CA2, CNR1, CYP1B1, DRD2, EGFR, ESRRB, F3, HCAR2, HSPA1A, HTR2A, HTR2B, KDR, KIT, MET, MIF, MMP12, MMP9, OPRM1, PDE3A, PIM1, PRKCA, PRKCB, PRKCE, PTGS2, SMAD3, SRC, TEK, TERT, TRPV1 |
6.50764 |
|
[BP] GO:0032101 |
regulation of response to external stimulus
|
ADORA1, CNR1, CNR2, CYP19A1, DRD1, DRD2, EGFR, ESR1, F3, FABP4, KDR, MET, MIF, MMP12, OPRM1, PPARA, PRKCA, PRKCD, PRKCG, PTGS2, PTPRS, SMAD3, TEK |
6.36997 |
|
[BP] GO:0016310 |
phosphorylation
|
APP, AURKB, AXL, BCL2, CDC25B, CSNK2A1, DRD1, DYRK1A, EGFR, FLT3, HTR2B, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TNKS |
6.33214 |
|
[BP] GO:0050790 |
regulation of catalytic activity
|
ADORA1, ADORA3, APP, AR, AURKB, BCL2, CDC25B, CNR1, CNR2, CSNK2A1, DRD1, DRD2, DUSP3, EGFR, ESR1, F3, FABP4, FLT3, HSPA1A, HTR2A, HTR2B, IGF1R, INSR, KIT, MIF, MMP9, NUAK1, OPRM1, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, XDH |
6.27756 |
|
[BP] GO:0048585 |
negative regulation of response to stimulus
|
ADORA1, ALOX15, AR, BCL2, CNR1, CNR2, CYP19A1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, HSPA1A, IGF1R, MET, MIF, MMP12, MMP9, PDE3B, PPARA, PRKCB, PRKCD, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TEK, TERT, XDH |
6.26718 |
|
[BP] GO:0009410 |
None
|
CNR1, CNR2, DRD1, DRD2, EGFR, HTR1B, NR3C1, OPRK1, OPRM1, PRKCE, PRKCG |
6.23937 |
|
[BP] GO:0042445 |
hormone metabolic process
|
ACHE, AKR1B1, AKR1C3, CYP19A1, CYP1A1, CYP1B1, CYP3A4, ESR1, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
6.20805 |
|
[BP] GO:0018108 |
peptidyl-tyrosine phosphorylation
|
AXL, DYRK1A, EGFR, FLT3, IGF1R, INSR, KDR, KIT, MET, PRKCD, SRC, TEK |
6.18373 |
|
[BP] GO:1901699 |
cellular response to nitrogen compound
|
AKR1B1, APEX1, APP, DNMT1, DRD1, EGFR, HTR1B, IGF1R, INSR, MMP2, OPRM1, PDE3A, PDE3B, PRKCD, PTGS2, SRC, TRPV1 |
6.17302 |
|
[BP] GO:0031323 |
regulation of cellular metabolic process
|
ACHE, ADORA1, ADORA3, AKR1C3, ALOX15, APEX1, APP, AR, AURKB, BCL2, CA9, CDC25B, CNR1, CSNK2A1, CYP1B1, CYP2D6, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GLO1, HSPA1A, HTR1A, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, NR3C1, NR3C2, NUAK1, OPRD1, OPRK1, OPRM1, PGR, PIK3CA, PIK3CB, PIM1, POLA1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SOAT1, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
6.15983 |
|
[BP] GO:0051966 |
regulation of synaptic transmission, glutamatergic
|
ADORA1, CNR1, DRD1, DRD2, EGFR, HTR1B, HTR2A, PTGS2 |
6.15524 |
|
[BP] GO:0018193 |
peptidyl-amino acid modification
|
AURKB, AXL, BCL2, CSNK2A1, DRD1, DYRK1A, EGFR, F10, FLT3, IGF1R, INSR, KDR, KIT, MET, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SENP6, SRC, TEK, TNKS, TOP2A |
6.14888 |
|
[BP] GO:0018212 |
peptidyl-tyrosine modification
|
AXL, DYRK1A, EGFR, FLT3, IGF1R, INSR, KDR, KIT, MET, PRKCD, SRC, TEK |
6.11783 |
|
[BP] GO:0048513 |
animal organ development
|
ACHE, AKR1C3, AR, AXL, BCL2, CA2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, EGFR, ESR1, ESRRA, ESRRB, FLT3, HSD11B1, HSD17B2, INSR, KDR, KIT, PIK3CA, POLB, PPARA, PTPRS, SMAD3, SRC, TEK, TYR |
6.08461 |
|
[BP] GO:0007200 |
None
|
DRD1, DRD2, ESR1, HTR2A, HTR2B, HTR2C, OPRD1, OPRK1, OPRM1 |
6.05863 |
|
[BP] GO:0042446 |
hormone biosynthetic process
|
AKR1B1, AKR1C3, CYP19A1, CYP3A4, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
6.04928 |
|
[BP] GO:0009987 |
cellular process
|
ABCB1, ACHE, ADORA1, ADORA3, AKR1B1, AKR1B10, AKR1C3, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CBR1, CDC25B, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, FUT7, GLO1, GPR35, HCAR2, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MET, MIF, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NR3C2, NUAK1, OPRD1, OPRK1, OPRM1, PDE10A, PDE3A, PDE3B, PGR, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SENP6, SIGMAR1, SLC22A1, SLC22A2, SMAD3, SOAT1, SOAT2, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, TUBB3, TYR, XDH |
6.03226 |
|
[BP] GO:0007267 |
None
|
ADORA1, AR, CNR1, DRD1, DRD2, ESR2, HTR1B, HTR1D, HTR1E, HTR2A, HTR2C, HTR4, HTR6, HTR7, OPRD1, OPRK1, OPRM1, PGR, PRKCG, TEK |
5.95477 |
|
[BP] GO:0031324 |
negative regulation of cellular metabolic process
|
AKR1C3, APEX1, APP, AR, AURKB, BCL2, CNR1, CSNK2A1, CYP2D6, DNMT1, DRD2, DUSP3, DYRK1A, ESR1, ESR2, ESRRA, FABP4, HSPA1A, HTR1B, HTR1E, HTR2B, IGF1R, MET, MIF, MMP12, MMP9, NR3C1, OPRM1, PIK3CA, PPARA, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TRPV1, XDH |
5.89553 |
|
[BP] GO:0050805 |
negative regulation of synaptic transmission
|
ACHE, ADORA1, CNR2, DRD1, DRD2, HTR1B, HTR2A, PTGS2 |
5.88976 |
|
[BP] GO:0050795 |
None
|
ADORA1, CNR1, DRD2, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B |
5.88976 |
|
[BP] GO:0097746 |
None
|
ADORA1, DRD1, EGFR, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PTGS2 |
5.85544 |
|
[BP] GO:0035296 |
None
|
ADORA1, DRD1, EGFR, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PTGS2 |
5.85544 |
|
[BP] GO:0007268 |
None
|
DRD1, DRD2, HTR1B, HTR1D, HTR1E, HTR2A, HTR2C, HTR4, HTR6, HTR7, OPRD1, OPRK1, OPRM1, PRKCG |
5.85011 |
|
[BP] GO:0098916 |
None
|
DRD1, DRD2, HTR1B, HTR1D, HTR1E, HTR2A, HTR2C, HTR4, HTR6, HTR7, OPRD1, OPRK1, OPRM1, PRKCG |
5.85011 |
|
[BP] GO:0009894 |
regulation of catabolic process
|
ADORA1, APEX1, BCL2, CNR1, CSNK2A1, EGFR, ESRRB, HCAR2, HSPA1A, HTR2A, HTR2B, INSR, KDR, MET, PDE3B, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, PRKCG, PTPN1, SMAD3 |
5.8343 |
|
[BP] GO:0044093 |
positive regulation of molecular function
|
ABCB1, ADORA1, APP, AR, AURKB, BCL2, CDC25B, DRD2, EGFR, ESR1, ESR2, F3, FLT3, HSPA1A, HTR2A, HTR2B, INSR, KIT, MET, MIF, MMP9, OPRD1, PIK3CA, PIK3CB, PRKCB, PRKCD, PRKCE, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, XDH |
5.76266 |
|
[BP] GO:1901652 |
response to peptide
|
AKR1B1, APEX1, APP, FABP3, HSD11B2, IGF1R, INSR, OPRK1, PDE3B, PPARA, PRKCD, PTGS2, SRC, TEK, TRPV1 |
5.74844 |
|
[BP] GO:0018105 |
peptidyl-serine phosphorylation
|
AURKB, BCL2, DRD1, DYRK1A, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TNKS |
5.73337 |
|
[BP] GO:0009755 |
hormone-mediated signaling pathway
|
AR, ESR1, ESR2, ESRRA, ESRRB, NR3C1, NR3C2, PGR, PPARA, RORC, SRC |
5.68283 |
|
[BP] GO:0008283 |
cell proliferation
|
ABCB1, ACHE, AR, AURKB, BCL2, CYP1A1, EGFR, ESR1, FLT3, HTR1A, KIT, MET, MIF, PIK3CB, PIM1, POLA1, PRKCD, SRC, TEK, TYR |
5.66793 |
|
[BP] GO:0050880 |
None
|
ADORA1, DRD1, EGFR, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PTGS2 |
5.6168 |
|
[BP] GO:1901615 |
organic hydroxy compound metabolic process
|
AKR1B1, AKR1B10, AKR1C3, ALOX15, APP, BCL2, CYP19A1, CYP1A1, CYP1B1, CYP3A4, DRD1, DRD2, HTR1A, SOAT1, SOAT2, TYR |
5.6038 |
|
[BP] GO:0035150 |
None
|
ADORA1, DRD1, EGFR, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PTGS2 |
5.59017 |
|
[BP] GO:0030522 |
intracellular receptor signaling pathway
|
AR, ESR1, ESR2, ESRRA, ESRRB, NR3C1, PGR, PIM1, PPARA, RORC, SRC |
5.48927 |
|
[BP] GO:0035556 |
intracellular signal transduction
|
AKR1B1, AXL, BCL2, CYP1B1, DNMT1, DRD1, DRD2, EGFR, HTR2A, HTR2B, HTR5A, IGF1R, INSR, KDR, KIT, MET, MIF, NUAK1, OPRM1, PDE3A, PIK3CA, PIK3CB, POLB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, SRC, TEK |
5.48438 |
|
[BP] GO:0006939 |
None
|
DRD1, DRD2, HTR1D, HTR2A, HTR2B, HTR7, TRPV1 |
5.48438 |
|
[BP] GO:0006820 |
anion transport
|
ABCB1, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, DRD2, FABP3, PPARA, SLC22A1, SLC22A2, SLC22A3, TRPV1 |
5.46557 |
|
[BP] GO:0048545 |
response to steroid hormone
|
AKR1C3, ALPL, AR, BCL2, CA2, EGFR, FLT3, HSD11B2, HTR1B, NR3C1, PTGS2, SRC |
5.46526 |
|
[BP] GO:0042310 |
None
|
HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7 |
5.45265 |
|
[BP] GO:0051050 |
positive regulation of transport
|
ABCB1, ACHE, ADORA1, APP, AXL, BCL2, CA2, CYP19A1, DRD1, DRD2, EGFR, HCAR2, HTR2B, INSR, MIF, MMP12, OPRK1, PRKCD, PRKCE, PTGS2, SMAD3, SRC, TERT, TRPV1 |
5.44355 |
|
[BP] GO:0010038 |
response to metal ion
|
AKR1C3, ALOX15, APP, BCL2, CA2, CYP1A1, CYP1A2, DRD2, EGFR, FABP4, KIT, MMP9, PTGS2, TERT |
5.41092 |
|
[BP] GO:0043271 |
negative regulation of ion transport
|
ADORA1, BCL2, CNR1, DRD2, GPR35, HTR1B, HTR2A, MMP9, PRKCE, PTGS2 |
5.36991 |
|
[BP] GO:0032268 |
regulation of cellular protein metabolic process
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, CSNK2A1, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, F3, FABP4, FLT3, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MIF, MMP9, NUAK1, OPRD1, OPRK1, OPRM1, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SMAD3, SRC, TEK, XDH |
5.36991 |
|
[BP] GO:0051171 |
regulation of nitrogen compound metabolic process
|
ADORA1, ADORA3, ALOX15, APEX1, APP, AR, AURKB, BCL2, CA9, CDC25B, CSNK2A1, CYP1B1, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GLO1, HSPA1A, HTR1A, HTR1B, HTR1E, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, NR3C1, NR3C2, NUAK1, OPRD1, OPRK1, OPRM1, PGR, PIK3CA, PIK3CB, PIM1, POLA1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SOAT1, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
5.34868 |
|
[BP] GO:0006721 |
terpenoid metabolic process
|
AKR1B10, AKR1C3, CYP1A1, CYP1A2, CYP1B1, CYP2D6, CYP3A4, EGFR, PDE3A |
5.33338 |
|
[BP] GO:0032846 |
positive regulation of homeostatic process
|
AURKB, CA2, CA7, CNR1, DRD1, DRD2, EGFR, HCAR2, PIK3CB, PTGS2, TNKS, TNKS2 |
5.3305 |
|
[BP] GO:0034754 |
cellular hormone metabolic process
|
AKR1B1, AKR1C3, CYP19A1, CYP1A1, CYP1B1, CYP3A4, ESR1, HSD17B1, HSD17B2 |
5.30325 |
|
[BP] GO:0034614 |
cellular response to reactive oxygen species
|
AKR1B1, AKR1C3, APEX1, AXL, CYP1B1, EGFR, MMP9, PRKCD, SRC |
5.30325 |
|
[BP] GO:0018209 |
peptidyl-serine modification
|
AURKB, BCL2, DRD1, DYRK1A, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TNKS |
5.29518 |
|
[BP] GO:0050994 |
None
|
ADORA1, CNR1, HCAR2, PDE3B, PPARA, PRKCD, PRKCE |
5.26275 |
|
[BP] GO:0023052 |
None
|
ADORA1, AR, CNR1, DRD1, DRD2, ESR2, HTR1B, HTR1D, HTR1E, HTR2A, HTR2C, HTR4, HTR6, HTR7, OPRD1, OPRK1, OPRM1, PGR, PRKCG, TEK |
5.25038 |
|
[BP] GO:0030168 |
platelet activation
|
AXL, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC |
5.24221 |
|
[BP] GO:0009698 |
phenylpropanoid metabolic process
|
CYP1A1, CYP2A13, CYP2A6, CYP2D6 |
5.21193 |
|
[BP] GO:0009804 |
coumarin metabolic process
|
CYP1A1, CYP2A13, CYP2A6, CYP2D6 |
5.21193 |
|
[BP] GO:0043278 |
None
|
CNR1, DRD2, OPRK1, OPRM1, PRKCE, PRKCG |
5.21193 |
|
[BP] GO:0014072 |
None
|
CNR1, DRD2, OPRK1, OPRM1, PRKCE, PRKCG |
5.21193 |
|
[BP] GO:0006805 |
xenobiotic metabolic process
|
CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2D6, CYP3A4, NQO2, PTGS1, RORC |
5.11568 |
|
[BP] GO:0044092 |
negative regulation of molecular function
|
ADORA3, APP, AURKB, CNR1, CNR2, CSNK2A1, CYP1B1, CYP2D6, DRD2, DUSP3, ESR1, FABP4, GPR35, IGF1R, MET, MMP9, OPRM1, PIM1, PPARA, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TNKS |
5.10953 |
|
[BP] GO:0043405 |
regulation of MAP kinase activity
|
ADORA1, DUSP3, EGFR, FLT3, HTR2A, HTR2B, IGF1R, INSR, KIT, MIF, PIK3CB, PRKCD, PTPN1, SRC |
5.10206 |
|
[BP] GO:0006979 |
response to oxidative stress
|
AKR1B1, AKR1C3, APEX1, APP, AXL, BCL2, CYP1B1, EGFR, HSPA1A, MMP9, PRKCD, PTGS1, PTGS2, SRC |
5.05678 |
|
[BP] GO:1901564 |
organonitrogen compound metabolic process
|
ACHE, AKR1B1, ALPL, AOX1, APP, AR, AURKB, AXL, BACE1, BCL2, CDC25B, CSNK2A1, CYP1A1, CYP1A2, CYP2D6, CYP3A4, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, F10, F3, FLT3, FUT7, GLO1, HSPA1A, HTR1A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PDE10A, PDE3A, PDE3B, PIK3CA, PIM1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, PTPRS, SENP6, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TYR, XDH |
5.01803 |
|
[BP] GO:0031960 |
response to corticosteroid
|
AKR1C3, ALPL, BCL2, EGFR, FLT3, HSD11B2, HTR1B, NR3C1, PTGS2, SRC |
5.01771 |
|
[BP] GO:0072347 |
None
|
CNR1, DRD2, HTR1B, OPRK1, OPRM1, PRKCE, PRKCG |
5.00387 |
|
[BP] GO:0022414 |
reproductive process
|
AKR1B1, AKR1C3, ALPL, APP, AR, AXL, BCL2, CDC25B, CNR1, CYP19A1, CYP1A1, DRD1, EGFR, ESR1, ESRRB, HSD11B2, HSD17B2, INSR, KIT, MMP2, MMP9, OPRK1, OPRM1, PDE3A, PGR, PTGS2, SRC, TOP2A |
4.96626 |
|
[BP] GO:0038003 |
None
|
OPRD1, OPRK1, OPRM1, SIGMAR1 |
4.93819 |
|
[BP] GO:0009891 |
positive regulation of biosynthetic process
|
APP, AR, AURKB, DRD1, DRD2, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MET, MMP12, NR3C1, PGR, PPARA, PRKCD, PTGS2, RORC, SMAD3, SOAT1, SRC, TERT, TNKS, TNKS2, TOP2A, TRPV1 |
4.93815 |
|
[BP] GO:0051046 |
None
|
ACHE, ADORA1, CNR1, CYP19A1, DRD2, EGFR, HCAR2, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, MIF, MMP12, OPRK1, OPRM1, PRKCA, PRKCE, SRC, TRPV1 |
4.93169 |
|
[BP] GO:0050806 |
positive regulation of synaptic transmission
|
ADORA1, APP, CA2, CA7, DRD1, DRD2, EGFR, PRKCE, PTGS2 |
4.91747 |
|
[BP] GO:0006367 |
transcription initiation from RNA polymerase II promoter
|
AR, ESR1, ESR2, ESRRA, ESRRB, NR3C1, NR3C2, PGR, PPARA, RORC |
4.90708 |
|
[BP] GO:0060359 |
None
|
CNR1, DRD1, DRD2, HTR1B, OPRK1, OPRM1, PRKCE, PRKCG |
4.89822 |
|
[BP] GO:0050801 |
ion homeostasis
|
APP, BCL2, CA12, CA2, CA7, DRD1, DRD2, EGFR, ESR1, FABP3, GPR35, HTR2A, HTR2B, HTR2C, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
4.89019 |
|
[BP] GO:2000379 |
positive regulation of reactive oxygen species metabolic process
|
AKR1C3, EGFR, INSR, PRKCD, PTGS2, SMAD3, TRPV1, XDH |
4.82621 |
|
[BP] GO:0072507 |
divalent inorganic cation homeostasis
|
APP, BCL2, DRD1, DRD2, EGFR, ESR1, GPR35, HTR2A, HTR2B, HTR2C, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
4.82621 |
|
[BP] GO:0032787 |
None
|
AKR1C3, ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, FABP3, GLO1, MIF, PPARA, PTGS1, PTGS2 |
4.82426 |
|
[BP] GO:0001505 |
regulation of neurotransmitter levels
|
ACHE, CYP1B1, DRD1, DRD2, EGFR, HTR1A, INSR, PTGS2, SLC22A2, SLC22A3, SMAD3, TRPV1 |
4.81894 |
|
[BP] GO:0006720 |
isoprenoid metabolic process
|
AKR1B10, AKR1C3, CYP1A1, CYP1A2, CYP1B1, CYP2D6, CYP3A4, EGFR, PDE3A |
4.81125 |
|
[BP] GO:0043279 |
None
|
CNR1, DRD2, HTR1B, OPRK1, OPRM1, PRKCE, PRKCG, TRPV1 |
4.79496 |
|
[BP] GO:1903530 |
regulation of secretion by cell
|
ACHE, ADORA1, CNR1, CYP19A1, DRD2, EGFR, HCAR2, HTR1A, HTR1B, HTR2A, HTR2B, HTR2C, MIF, MMP12, OPRK1, OPRM1, PRKCA, PRKCE, SRC |
4.77243 |
|
[BP] GO:0050794 |
regulation of cellular process
|
ACHE, ADORA1, ADORA3, AKR1B1, AKR1C3, ALOX15, APEX1, APP, AR, AURKB, AXL, BACE1, BCL2, CA1, CA2, CA7, CA9, CDC25B, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, CYP2D6, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, GLO1, GPR35, HCAR2, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MET, MIF, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, NUAK1, OPRD1, OPRK1, OPRM1, PDE10A, PDE3A, PDE3B, PGR, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SENP6, SIGMAR1, SMAD3, SOAT1, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
4.72986 |
|
[BP] GO:0008610 |
lipid biosynthetic process
|
ACHE, AKR1B1, AKR1C3, ALOX15, CSNK2A1, CYP19A1, CYP1A1, CYP3A4, HSD11B1, HSD11B2, HSD17B1, HSD17B2, MIF, PIK3CA, PIK3CB, PTGS1, PTGS2 |
4.71734 |
|
[BP] GO:0071073 |
None
|
FABP3, HTR2A, HTR2B, HTR2C |
4.71541 |
|
[BP] GO:0051246 |
regulation of protein metabolic process
|
ADORA1, ALOX15, APP, AR, BCL2, CDC25B, CSNK2A1, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, F3, FABP4, FLT3, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MIF, MMP9, NUAK1, OPRD1, OPRK1, OPRM1, PIK3CA, PIK3CB, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, SMAD3, SOAT1, SRC, TEK, XDH |
4.71237 |
|
[BP] GO:0019373 |
epoxygenase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6 |
4.71221 |
|
[BP] GO:2000377 |
regulation of reactive oxygen species metabolic process
|
AKR1C3, BCL2, CYP1B1, EGFR, INSR, PRKCD, PTGS2, SMAD3, TRPV1, XDH |
4.71058 |
|
[BP] GO:0009895 |
negative regulation of catabolic process
|
ADORA1, BCL2, CNR1, EGFR, HCAR2, HTR2B, MET, PDE3B, PIK3CA, PPARA, PRKCG, SMAD3 |
4.6945 |
|
[BP] GO:0046883 |
regulation of hormone secretion
|
ADORA1, CNR1, CYP19A1, DRD2, EGFR, HCAR2, HTR1A, HTR2A, HTR2C, OPRK1, PRKCA, PRKCE |
4.6945 |
|
[BP] GO:0045787 |
positive regulation of cell cycle
|
APEX1, APP, AURKB, CDC25B, CYP1A1, DRD2, DUSP3, EGFR, INSR, MIF, PRKCA, PRKCE, SRC, TERT |
4.6945 |
|
[BP] GO:0007631 |
None
|
APP, DRD1, DRD2, HTR1B, HTR2C, OPRD1, OPRK1, OPRM1 |
4.66847 |
|
[BP] GO:0031328 |
positive regulation of cellular biosynthetic process
|
APP, AR, AURKB, DRD1, DRD2, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, HTR2A, HTR2B, HTR2C, IGF1R, INSR, MET, MMP12, NR3C1, PGR, PPARA, PRKCD, PTGS2, RORC, SMAD3, SOAT1, SRC, TERT, TNKS, TNKS2, TOP2A, TRPV1 |
4.62321 |
|
[BP] GO:0007169 |
transmembrane receptor protein tyrosine kinase signaling pathway
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, KIT, MET, MMP2, MMP9, PIK3CA, PIK3CB, PRKCA, PTPN1, SRC, TEK |
4.61211 |
|
[BP] GO:0000302 |
response to reactive oxygen species
|
AKR1B1, AKR1C3, APEX1, AXL, BCL2, CYP1B1, EGFR, MMP9, PRKCD, SRC |
4.60309 |
|
[BP] GO:0006874 |
cellular calcium ion homeostasis
|
APP, BCL2, DRD1, DRD2, ESR1, GPR35, HTR2A, HTR2B, HTR2C, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
4.56224 |
|
[BP] GO:0051130 |
positive regulation of cellular component organization
|
ALOX15, APP, AR, AURKB, AXL, BCL2, CNR1, DNMT1, DRD2, ESR1, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP9, PRKCD, PRKCE, SMAD3, SRC, TEK, TNKS, TNKS2 |
4.55566 |
|
[BP] GO:0050890 |
None
|
ADORA1, APP, CNR1, DRD1, DRD2, EGFR, HTR2A, INSR, KIT, OPRK1, PRKCG, PTGS2 |
4.54866 |
|
[BP] GO:0098771 |
inorganic ion homeostasis
|
APP, BCL2, CA12, CA2, CA7, DRD1, DRD2, EGFR, ESR1, GPR35, HTR2A, HTR2B, HTR2C, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
4.50771 |
|
[BP] GO:0009611 |
response to wounding
|
ACHE, ADORA3, ALOX15, BCL2, CYP1A1, DRD2, EGFR, OPRM1, PPARA, SMAD3 |
4.49775 |
|
[BP] GO:0002682 |
regulation of immune system process
|
ADORA1, ALOX15, APP, AXL, BCL2, CA2, CNR1, CNR2, CYP19A1, DRD2, DUSP3, ESR1, ESRRA, HCAR2, HSPA1A, KIT, MIF, MMP12, MMP2, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTPN1, PTPRS, SMAD3, SRC |
4.49775 |
|
[BP] GO:0031347 |
regulation of defense response
|
ADORA1, CNR1, CNR2, CYP19A1, DRD2, EGFR, ESR1, FABP4, HSPA1A, MMP12, MMP2, PPARA, PRKCD, PRKCE, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TEK |
4.49373 |
|
[BP] GO:0043434 |
None
|
APEX1, FABP3, HSD11B2, INSR, OPRK1, PDE3B, PPARA, PRKCD, PTGS2, SRC, TEK, TRPV1 |
4.45607 |
|
[BP] GO:0032098 |
None
|
HTR2C, HTR4, OPRM1, PPARA, SLC22A3 |
4.42483 |
|
[BP] GO:1902532 |
negative regulation of intracellular signal transduction
|
BCL2, DRD2, DUSP3, DYRK1A, ESR1, HSPA1A, IGF1R, MET, MIF, MMP9, PDE3B, PRKCD, PTGS2, PTPN1, SRC, XDH |
4.4241 |
|
[BP] GO:0055074 |
calcium ion homeostasis
|
APP, BCL2, DRD1, DRD2, ESR1, GPR35, HTR2A, HTR2B, HTR2C, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
4.41592 |
|
[BP] GO:0044057 |
None
|
ADORA1, ADORA3, DRD2, EGFR, GPR35, HCAR2, HTR2A, HTR2C, KIT, OPRD1, OPRK1, OPRM1, PRKCA, PTGS2, SMAD3, TRPV1 |
4.40462 |
|
[BP] GO:0050730 |
None
|
ADORA1, APP, EGFR, FLT3, HTR2A, KIT, MIF, PRKCD, PRKCE, PTPN1, SRC |
4.39903 |
|
[BP] GO:0007568 |
aging
|
APEX1, AURKB, BCL2, CNR1, CYP1A1, HTR2A, MIF, POLB, PRKCD, PTGS2, TERT |
4.39903 |
|
[BP] GO:0051209 |
None
|
DRD2, HTR2A, HTR2B, HTR2C, PRKCE, TRPV1 |
4.38037 |
|
[BP] GO:0051283 |
None
|
DRD2, HTR2A, HTR2B, HTR2C, PRKCE, TRPV1 |
4.38037 |
|
[BP] GO:0072503 |
cellular divalent inorganic cation homeostasis
|
APP, BCL2, DRD1, DRD2, ESR1, GPR35, HTR2A, HTR2B, HTR2C, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
4.35845 |
|
[BP] GO:0001775 |
cell activation
|
ALOX5, APP, AXL, BCL2, EGFR, FLT3, FUT7, HSPA1A, KIT, MIF, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, RORC, SMAD3, SRC, TRPV1 |
4.35436 |
|
[BP] GO:0019371 |
None
|
AKR1C3, CBR1, PTGS1, PTGS2 |
4.34358 |
|
[BP] GO:0007611 |
None
|
APP, CNR1, DRD1, DRD2, EGFR, HTR2A, INSR, KIT, OPRK1, PRKCG, PTGS2 |
4.33329 |
|
[BP] GO:0017144 |
drug metabolic process
|
ACHE, AKR1B1, AKR1B10, AKR1C3, AOX1, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP2D6, CYP3A4, DRD1, DRD2, EGFR, HSPA1A |
4.31807 |
|
[BP] GO:0032870 |
cellular response to hormone stimulus
|
AKR1C3, APEX1, AR, EGFR, ESR1, FLT3, INSR, KIT, NR3C1, PDE3B, PRKCD, PRKCE, SRC |
4.31735 |
|
[BP] GO:0090087 |
None
|
ACHE, ADORA1, APP, CA2, CNR1, DRD2, EGFR, HCAR2, HTR2B, HTR2C, MIF, MMP12, OPRM1, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC |
4.30469 |
|
[BP] GO:0006811 |
None
|
ABCB1, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, DRD1, DRD2, FABP3, HTR2A, HTR2B, HTR2C, OPRM1, PPARA, PRKCB, PRKCE, SLC22A1, SLC22A2, SLC22A3, SLC47A1, TRPV1 |
4.28508 |
|
[BP] GO:0003006 |
developmental process involved in reproduction
|
AKR1C3, ALPL, AR, AXL, BCL2, CDC25B, CYP19A1, EGFR, ESR1, ESRRB, HSD17B2, INSR, KIT, PDE3A, PGR, PTGS2, SRC |
4.27705 |
|
[BP] GO:0008217 |
None
|
ADORA1, AR, CNR1, DRD2, HSD11B2, PPARA, PTGS1, PTGS2, SMAD3 |
4.22777 |
|
[BP] GO:0051952 |
None
|
ADORA1, CNR1, DRD1, DRD2, HTR1B, HTR2A, OPRK1 |
4.22757 |
|
[BP] GO:0048661 |
positive regulation of smooth muscle cell proliferation
|
AKR1B1, EGFR, HTR1B, MMP2, MMP9, PTGS2, TERT |
4.22757 |
|
[BP] GO:0034599 |
cellular response to oxidative stress
|
AKR1B1, AKR1C3, APEX1, AXL, CYP1B1, EGFR, HSPA1A, MMP9, PRKCD, SRC |
4.21318 |
|
[BP] GO:0015872 |
None
|
DRD1, SLC22A1, SLC22A2, SLC22A3 |
4.18796 |
|
[BP] GO:0050793 |
regulation of developmental process
|
APP, AR, AXL, BCL2, CA2, CNR1, CYP1B1, DRD2, EGFR, ESR1, ESRRA, ESRRB, F3, HTR2A, HTR2C, INSR, KDR, KIT, MIF, NUAK1, OPRM1, PDE3A, PDE3B, PIK3CA, PIM1, PPARA, PRKCA, PRKCB, PTGS2, PTPRS, RORC, SMAD3, SRC, TEK, TERT, TNKS2, TRPV1, XDH |
4.16638 |
|
[BP] GO:0018107 |
peptidyl-threonine phosphorylation
|
BCL2, CSNK2A1, DYRK1A, PRKCA, PRKCB, PRKCD, TNKS |
4.15792 |
|
[BP] GO:0051347 |
positive regulation of transferase activity
|
ADORA1, AURKB, CDC25B, DRD2, EGFR, FLT3, HTR2A, HTR2B, INSR, KIT, MIF, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC, TEK, TNKS |
4.14779 |
|
[BP] GO:0016477 |
cell migration
|
AXL, CNR2, CYP1B1, DRD1, DRD2, EGFR, FUT7, HTR2B, HTR6, KDR, KIT, MIF, MMP1, MMP12, MMP9, PIK3CA, PIK3CB, PRKCD, SRC, TEK |
4.13642 |
|
[BP] GO:0033674 |
positive regulation of kinase activity
|
ADORA1, CDC25B, DRD2, EGFR, FLT3, HTR2A, HTR2B, INSR, KIT, MIF, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC, TEK |
4.13071 |
|
[BP] GO:0043085 |
positive regulation of catalytic activity
|
ADORA1, APP, AURKB, BCL2, CDC25B, DRD2, EGFR, ESR1, F3, FLT3, HSPA1A, HTR2A, HTR2B, INSR, KIT, MIF, PIK3CA, PIK3CB, PRKCD, PRKCE, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, XDH |
4.1197 |
|
[BP] GO:0016572 |
histone phosphorylation
|
AURKB, DRD1, PRKCA, PRKCB, PRKCD |
4.11451 |
|
[BP] GO:0014059 |
None
|
CNR1, DRD2, HTR1B, HTR2A, OPRK1 |
4.11451 |
|
[BP] GO:0032847 |
regulation of cellular pH reduction
|
BCL2, CA2, CA7 |
4.10717 |
|
[BP] GO:0051726 |
regulation of cell cycle
|
APEX1, APP, AURKB, BCL2, CDC25B, CSNK2A1, CYP1A1, DRD2, DUSP3, EGFR, HSPA1A, INSR, MIF, PDE3A, PIM1, PRKCA, PRKCE, PTGS2, SENP6, SMAD3, SRC, TERT, TNKS, TOP2A |
4.08521 |
|
[BP] GO:0008150 |
biological_process
|
ABCB1, ACHE, ADORA1, ADORA3, AKR1B1, AKR1B10, AKR1C3, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CBR1, CDC25B, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, FUT7, GLO1, GPR35, HCAR2, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MET, MIF, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NR3C2, NUAK1, OPRD1, OPRK1, OPRM1, PDE10A, PDE3A, PDE3B, PGR, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SENP6, SIGMAR1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SMAD3, SOAT1, SOAT2, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, TUBB3, TYR, XDH |
4.06329 |
|
[BP] GO:0060255 |
regulation of macromolecule metabolic process
|
ACHE, ADORA1, ADORA3, ALOX15, APEX1, APP, AR, AURKB, BCL2, CA9, CDC25B, CSNK2A1, CYP1A2, CYP1B1, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP4, FLT3, GLO1, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP9, NR3C1, NR3C2, NUAK1, OPRD1, OPRK1, OPRM1, PGR, PIK3CA, PIK3CB, PIM1, POLA1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SOAT1, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
4.05671 |
|
[BP] GO:0043549 |
regulation of kinase activity
|
ADORA1, APP, CDC25B, DRD2, DUSP3, EGFR, FABP4, FLT3, HTR2A, HTR2B, IGF1R, INSR, KIT, MIF, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC, TEK |
4.04282 |
|
[BP] GO:0051172 |
None
|
APEX1, APP, AR, AURKB, CSNK2A1, DNMT1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, FABP4, HSPA1A, HTR1B, HTR1E, IGF1R, MIF, MMP12, MMP9, NR3C1, OPRM1, PPARA, PRKCA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TRPV1, XDH |
4.04273 |
|
[BP] GO:0055080 |
cation homeostasis
|
APP, BCL2, CA2, CA7, DRD1, DRD2, EGFR, ESR1, GPR35, HTR2A, HTR2B, HTR2C, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
4.03298 |
|
[BP] GO:0051094 |
positive regulation of developmental process
|
APP, AR, AXL, BCL2, CA2, CNR1, CYP1B1, DRD2, ESRRB, F3, HTR2A, HTR2C, INSR, KDR, KIT, OPRM1, PDE3A, PIM1, PRKCA, PRKCB, PTGS2, SMAD3, SRC, TEK, TERT |
4.03114 |
|
[BP] GO:0006352 |
DNA-templated transcription, initiation
|
AR, ESR1, ESR2, ESRRA, ESRRB, NR3C1, NR3C2, PGR, PPARA, RORC |
4.02566 |
|
[BP] GO:0048871 |
multicellular organismal homeostasis
|
ADORA1, AKR1B1, DRD1, DRD2, HTR2A, MET, PIK3CA, TRPV1 |
4.02566 |
|
[BP] GO:0045935 |
positive regulation of nucleobase-containing compound metabolic process
|
APP, AR, AURKB, DNMT1, DRD1, DRD2, EGFR, ESR1, ESR2, ESRRA, ESRRB, HSPA1A, HTR2A, IGF1R, INSR, MET, MMP12, NR3C1, PGR, PPARA, PRKCD, PRKCG, PTPN1, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A |
4.0094 |
|
[BP] GO:0090066 |
None
|
ADORA1, ALOX15, DRD1, EGFR, HTR1A, HTR1B, HTR1D, HTR2A, HTR2B, HTR7, PRKCD, PRKCE, PTGS2 |
4.0094 |
|
[BP] GO:0048856 |
anatomical structure development
|
ACHE, ADORA1, AKR1B1, AKR1C3, ALOX15, ALPL, APP, AR, AXL, BCL2, CA2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESRRA, ESRRB, FLT3, HSD11B1, HSD17B2, HTR5A, INSR, KDR, KIT, MMP9, PGR, PIK3CA, PIM1, POLB, PPARA, PTGS2, PTPRS, RORC, SIGMAR1, SMAD3, SRC, TEK, TYR |
4.00922 |
|
[BP] GO:0019233 |
None
|
CNR1, CNR2, OPRD1, OPRK1, OPRM1, PTGS2 |
4.00624 |
|
[BP] GO:0051338 |
regulation of transferase activity
|
ADORA1, APP, AURKB, CDC25B, DRD2, DUSP3, EGFR, FABP4, FLT3, HTR2A, HTR2B, IGF1R, INSR, KIT, MIF, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC, TEK, TNKS |
4.00304 |
|
[BP] GO:0051051 |
negative regulation of transport
|
ADORA1, APP, BCL2, CNR1, DRD2, GPR35, HSPA1A, HTR1B, HTR2A, MMP9, OPRK1, OPRM1, PRKCB, PRKCE, PTGS2 |
4.00304 |
|
[BP] GO:0009968 |
negative regulation of signal transduction
|
AR, BCL2, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, HSPA1A, IGF1R, MET, MIF, MMP12, MMP9, PDE3B, PRKCB, PRKCD, PTGS2, PTPN1, PTPRS, SMAD3, SRC, TERT, XDH |
3.99038 |
|
[BP] GO:0097237 |
cellular response to toxic substance
|
AKR1B1, APEX1, AXL, CYP1B1, KDR, OPRD1, PRKCD, PRKCE |
3.98102 |
|
[BP] GO:0030003 |
cellular cation homeostasis
|
APP, BCL2, CA2, CA7, DRD1, DRD2, ESR1, GPR35, HTR2A, HTR2B, HTR2C, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
3.97084 |
|
[BP] GO:0006954 |
inflammatory response
|
ADORA1, ADORA3, ALOX15, AXL, CNR2, KIT, MIF, OPRM1, PIK3CA, PIK3CB, POLB, PTGS1, PTGS2, TRPV1 |
3.96587 |
|
[BP] GO:0019725 |
cellular homeostasis
|
APEX1, APP, BCL2, CA2, CA7, DRD1, DRD2, ESR1, GPR35, HTR2A, HTR2B, HTR2C, PIK3CA, PIK3CB, POLA1, PRKCB, PRKCE, SMAD3, TRPV1 |
3.95088 |
|
[BP] GO:0050789 |
regulation of biological process
|
ABCB1, ACHE, ADORA1, ADORA3, AKR1B1, AKR1C3, ALOX15, APEX1, APP, AR, AURKB, AXL, BACE1, BCL2, CA1, CA2, CA7, CA9, CDC25B, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, GLO1, GPR35, HCAR2, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MET, MIF, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, NUAK1, OPRD1, OPRK1, OPRM1, PDE10A, PDE3A, PDE3B, PGR, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SENP6, SIGMAR1, SMAD3, SOAT1, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, XDH |
3.9479 |
|
[BP] GO:0018210 |
peptidyl-threonine modification
|
BCL2, CSNK2A1, DYRK1A, PRKCA, PRKCB, PRKCD, TNKS |
3.94578 |
|
[BP] GO:0051967 |
None
|
ADORA1, DRD2, HTR1B, HTR2A |
3.93368 |
|
[BP] GO:0045859 |
regulation of protein kinase activity
|
ADORA1, APP, CDC25B, DRD2, DUSP3, EGFR, FABP4, FLT3, HTR2A, HTR2B, IGF1R, INSR, KIT, MIF, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC |
3.93238 |
|
[BP] GO:0001659 |
None
|
ADORA1, DRD1, DRD2, HTR2A, TRPV1 |
3.92287 |
|
[BP] GO:0014065 |
phosphatidylinositol 3-kinase signaling
|
HTR2A, HTR2B, IGF1R, PIK3CA, PIK3CB |
3.92287 |
|
[BP] GO:0043406 |
positive regulation of MAP kinase activity
|
ADORA1, EGFR, FLT3, HTR2A, HTR2B, INSR, KIT, MIF, PIK3CB, PTPN1, SRC |
3.9085 |
|
[BP] GO:0051054 |
positive regulation of DNA metabolic process
|
AURKB, DNMT1, EGFR, IGF1R, INSR, PRKCD, PRKCG, SRC, TNKS, TNKS2 |
3.90096 |
|
[BP] GO:0046686 |
response to cadmium ion
|
AKR1C3, CYP1A2, EGFR, KIT, MMP9, TERT |
3.88479 |
|
[BP] GO:0080135 |
regulation of cellular response to stress
|
APP, DUSP3, DYRK1A, EGFR, HSPA1A, IGF1R, MET, MIF, NUAK1, OPRK1, PRKCD, PRKCG, PTGS2, PTPN1, PTPRS, TERT, XDH |
3.8714 |
|
[BP] GO:0051047 |
None
|
ACHE, ADORA1, CYP19A1, DRD2, EGFR, HCAR2, HTR2B, MIF, MMP12, OPRK1, PRKCE, SRC, TRPV1 |
3.8699 |
|
[BP] GO:0010634 |
positive regulation of epithelial cell migration
|
KDR, MET, MMP9, PRKCA, PRKCE, PTGS2, SRC, TEK |
3.86671 |
|
[BP] GO:0006873 |
cellular ion homeostasis
|
APP, BCL2, CA2, CA7, DRD1, DRD2, ESR1, GPR35, HTR2A, HTR2B, HTR2C, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
3.85357 |
|
[BP] GO:0097553 |
None
|
DRD2, HTR2A, HTR2B, HTR2C, PRKCE, TRPV1 |
3.84454 |
|
[BP] GO:0006694 |
steroid biosynthetic process
|
AKR1B1, AKR1C3, CYP19A1, CYP3A4, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
3.84454 |
|
[BP] GO:0051128 |
regulation of cellular component organization
|
ALOX15, APP, AR, AURKB, AXL, BCL2, CNR1, CSNK2A1, DNMT1, DRD2, EGFR, ESR1, ESR2, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP9, OPRD1, PDE3A, PIK3CB, PRKCD, PRKCE, PRKCG, PTPN1, PTPRS, SENP6, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
3.84454 |
|
[BP] GO:0055082 |
cellular chemical homeostasis
|
APP, BCL2, CA2, CA7, DRD1, DRD2, ESR1, GPR35, HTR2A, HTR2B, HTR2C, PIK3CA, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
3.84333 |
|
[BP] GO:0048869 |
cellular developmental process
|
ACHE, AKR1C3, ALPL, APP, AR, AXL, BCL2, CBR1, CDC25B, CYP1A1, DRD1, DRD2, EGFR, ESR1, ESRRB, FABP4, FLT3, FUT7, GLO1, HTR2B, KDR, KIT, MET, MIF, MMP2, MMP9, PDE3A, PGR, PRKCD, PTGS2, PTPRS, RORC, SMAD3, SOAT1, SOAT2, SRC, TEK, TERT, TOP2A |
3.84289 |
|
[BP] GO:0045860 |
positive regulation of protein kinase activity
|
ADORA1, CDC25B, DRD2, EGFR, FLT3, HTR2A, HTR2B, INSR, KIT, MIF, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC |
3.84221 |
|
[BP] GO:2001023 |
None
|
CNR1, DRD1, DRD2, HTR1B, HTR2A, MET, OPRK1 |
3.83309 |
|
[BP] GO:0051937 |
None
|
DRD1, SLC22A1, SLC22A2, SLC22A3 |
3.82352 |
|
[BP] GO:0031348 |
negative regulation of defense response
|
ADORA1, CNR2, CYP19A1, DRD2, MMP12, PPARA, PRKCD, SMAD3, TEK |
3.80733 |
|
[BP] GO:0010863 |
positive regulation of phospholipase C activity
|
EGFR, ESR1, HTR2A, HTR2B, KIT |
3.80236 |
|
[BP] GO:0002791 |
None
|
ACHE, ADORA1, CNR1, DRD2, EGFR, HCAR2, HTR2B, HTR2C, MIF, MMP12, OPRM1, PRKCA, PRKCE, SRC |
3.80226 |
|
[BP] GO:0071502 |
None
|
HTR1B, HTR2B, TRPV1 |
3.77095 |
|
[BP] GO:0010513 |
None
|
HTR2A, HTR2B, HTR2C |
3.77095 |
|
[BP] GO:1904018 |
positive regulation of vasculature development
|
CYP1B1, F3, KDR, KIT, PRKCA, PRKCB, PTGS2, TEK, TERT |
3.7302 |
|
[BP] GO:0071071 |
None
|
FABP3, HTR2A, HTR2B, HTR2C |
3.70948 |
|
[BP] GO:0032102 |
negative regulation of response to external stimulus
|
ADORA1, CNR2, CYP19A1, DRD1, DRD2, MIF, PPARA, PRKCD, PTPRS, SMAD3, TEK |
3.70568 |
|
[BP] GO:0032103 |
positive regulation of response to external stimulus
|
CNR1, EGFR, F3, FABP4, KDR, MET, MIF, OPRM1, PRKCA, PTGS2, SMAD3 |
3.70568 |
|
[BP] GO:0070848 |
response to growth factor
|
APP, EGFR, INSR, KDR, NR3C1, OPRD1, OPRM1, PDE3A, SMAD3, SRC, TRPV1 |
3.70568 |
|
[BP] GO:0021885 |
forebrain cell migration
|
AXL, DRD1, DRD2, EGFR, HTR6 |
3.68178 |
|
[BP] GO:0007167 |
enzyme linked receptor protein signaling pathway
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, KIT, MET, MMP2, MMP9, PIK3CA, PIK3CB, PRKCA, PTPN1, SMAD3, SRC, TEK |
3.67817 |
|
[BP] GO:2001243 |
negative regulation of intrinsic apoptotic signaling pathway
|
BCL2, HSPA1A, MIF, MMP9, PTGS2, PTPN1, SRC |
3.65881 |
|
[BP] GO:0051098 |
regulation of binding
|
APP, AURKB, BCL2, CYP2D6, MET, MMP9, PPARA, PRKCD, SMAD3, SRC, TERT, TNKS |
3.62342 |
|
[BP] GO:1900274 |
regulation of phospholipase C activity
|
EGFR, ESR1, HTR2A, HTR2B, KIT |
3.62342 |
|
[BP] GO:0048870 |
cell motility
|
AXL, CNR2, CYP1B1, DRD1, DRD2, EGFR, FUT7, HTR2B, HTR6, KDR, KIT, MIF, MMP1, MMP12, MMP9, PIK3CA, PIK3CB, PRKCD, SRC, TEK |
3.59442 |
|
[BP] GO:0046889 |
None
|
FABP3, HTR2A, HTR2B, HTR2C, PRKCD, PTGS2 |
3.57626 |
|
[BP] GO:0060402 |
None
|
DRD2, HTR2A, HTR2B, HTR2C, PRKCE, TRPV1 |
3.57626 |
|
[BP] GO:0006855 |
None
|
ABCB1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2 |
3.57626 |
|
[BP] GO:1900542 |
None
|
DRD1, DRD2, ESRRB, HTR1B, HTR1E, HTR2A, INSR, OPRM1, PPARA, PRKCA |
3.57565 |
|
[BP] GO:0046456 |
icosanoid biosynthetic process
|
ALOX15, ALOX5, MIF, PTGS1, PTGS2 |
3.56999 |
|
[BP] GO:0055065 |
metal ion homeostasis
|
APP, BCL2, DRD1, DRD2, EGFR, ESR1, GPR35, HTR2A, HTR2B, HTR2C, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
3.56122 |
|
[BP] GO:0033138 |
positive regulation of peptidyl-serine phosphorylation
|
APP, BCL2, EGFR, MIF, OPRD1, PIK3CA, PTGS2 |
3.55063 |
|
[BP] GO:0030534 |
None
|
APP, DRD1, DRD2, HTR2A, OPRD1, OPRK1, OPRM1, PPARA |
3.53672 |
|
[BP] GO:0048609 |
multicellular organismal reproductive process
|
AKR1B1, APP, AR, AXL, CNR1, CYP1A1, DRD1, EGFR, ESR1, KIT, OPRK1, OPRM1, PGR, PTGS2, SRC |
3.51663 |
|
[BP] GO:0014821 |
None
|
DRD1, DRD2, HTR1D, HTR2B |
3.50921 |
|
[BP] GO:0032229 |
None
|
ADORA1, CNR2, HTR1B |
3.50008 |
|
[BP] GO:0016098 |
monoterpenoid metabolic process
|
CYP1A2, CYP2D6, CYP3A4 |
3.50008 |
|
[BP] GO:0051234 |
None
|
ABCB1, ACHE, ADORA1, AKR1C3, ALOX15, ALOX5, APP, AR, AXL, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, DRD1, DRD2, EGFR, F10, FABP3, HSPA1A, HTR1B, HTR2A, HTR2B, HTR2C, KIT, MIF, MMP12, MMP9, OPRD1, OPRM1, PPARA, PRKCB, PRKCD, PRKCE, SIGMAR1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SOAT1, SOAT2, SRC, TERT, TNKS, TRPV1, XDH |
3.49727 |
|
[BP] GO:0006875 |
cellular metal ion homeostasis
|
APP, BCL2, DRD1, DRD2, ESR1, GPR35, HTR2A, HTR2B, HTR2C, PIK3CB, PRKCB, PRKCE, SMAD3, TRPV1 |
3.48323 |
|
[BP] GO:0006140 |
None
|
DRD1, DRD2, ESRRB, HTR1B, HTR1E, HTR2A, INSR, OPRM1, PPARA, PRKCA |
3.47592 |
|
[BP] GO:0045931 |
positive regulation of mitotic cell cycle
|
APEX1, APP, CDC25B, CYP1A1, DUSP3, INSR, PRKCA, TERT |
3.45638 |
|
[BP] GO:0040011 |
locomotion
|
AXL, CNR2, CYP1B1, DRD1, DRD2, EGFR, FUT7, HTR2B, HTR6, KDR, KIT, MET, MIF, MMP1, MMP12, MMP9, PIK3CA, PIK3CB, PRKCD, SRC, TEK |
3.45269 |
|
[BP] GO:0045913 |
None
|
ESRRB, HTR2A, INSR, PPARA, PRKCE, SRC |
3.43887 |
|
[BP] GO:0032880 |
regulation of protein localization
|
ACHE, APP, AR, BCL2, CNR1, CSNK2A1, DRD2, EGFR, HCAR2, HTR2B, MIF, MMP12, OPRM1, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TERT |
3.42985 |
|
[BP] GO:0071363 |
cellular response to growth factor stimulus
|
APP, EGFR, INSR, KDR, NR3C1, OPRD1, PDE3A, SMAD3, SRC, TRPV1 |
3.42006 |
|
[BP] GO:0015893 |
None
|
ABCB1, CA2, DRD1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2 |
3.37669 |
|
[BP] GO:0071248 |
cellular response to metal ion
|
AKR1C3, ALOX15, CYP1A1, CYP1A2, EGFR, FABP4, MMP9, PTGS2 |
3.37669 |
|
[BP] GO:0031644 |
None
|
ADORA1, GPR35, HTR2C, OPRD1, OPRK1, OPRM1 |
3.3722 |
|
[BP] GO:1904407 |
positive regulation of nitric oxide metabolic process
|
EGFR, INSR, PTGS2, SMAD3, TRPV1 |
3.3694 |
|
[BP] GO:0045429 |
positive regulation of nitric oxide biosynthetic process
|
EGFR, INSR, PTGS2, SMAD3, TRPV1 |
3.3694 |
|
[BP] GO:0009991 |
response to extracellular stimulus
|
AKR1C3, ALPL, AXL, BCL2, CNR1, CYP1A1, EGFR, HSD11B2, OPRM1, PTGS2, SRC, TRPV1, TYR |
3.35332 |
|
[BP] GO:0010564 |
regulation of cell cycle process
|
APEX1, APP, AURKB, BCL2, CDC25B, CSNK2A1, CYP1A1, DRD2, EGFR, HSPA1A, INSR, MIF, PDE3A, PRKCE, SENP6, TERT, TNKS |
3.34757 |
|
[BP] GO:0051179 |
None
|
ABCB1, ACHE, ADORA1, AKR1C3, ALOX15, ALOX5, APP, AR, AURKB, AXL, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, DRD1, DRD2, EGFR, ESR1, F10, FABP3, HSPA1A, HTR1B, HTR2A, HTR2B, HTR2C, KIT, MIF, MMP12, MMP9, OPRD1, OPRM1, PPARA, PRKCB, PRKCD, PRKCE, SIGMAR1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SOAT1, SOAT2, SRC, TERT, TNKS, TNKS2, TRPV1, XDH |
3.34658 |
|
[BP] GO:1900543 |
None
|
DRD2, HTR1B, HTR1E, OPRM1, PPARA, PRKCA |
3.34402 |
|
[BP] GO:0006952 |
defense response
|
ADORA1, ADORA3, ALOX15, APP, AXL, BCL2, CNR2, DRD1, HTR1A, HTR2C, KIT, MIF, OPRK1, OPRM1, PIK3CA, PIK3CB, POLB, PRKCD, PTGS1, PTGS2, SRC, TRPV1 |
3.34391 |
|
[BP] GO:0048148 |
None
|
DRD1, DRD2, HTR2A, OPRK1 |
3.34079 |
|
[BP] GO:0042542 |
response to hydrogen peroxide
|
AKR1B1, APEX1, AXL, BCL2, CYP1B1, PRKCD, SRC |
3.33087 |
|
[BP] GO:0071900 |
regulation of protein serine/threonine kinase activity
|
ADORA1, DUSP3, EGFR, FLT3, HTR2A, HTR2B, IGF1R, INSR, KIT, MIF, PIK3CB, PRKCD, PTPN1, SRC |
3.32655 |
|
[BP] GO:0007166 |
cell surface receptor signaling pathway
|
ADORA1, ADORA3, APP, AXL, BCL2, CA1, CSNK2A1, DRD2, EGFR, F3, FLT3, GPR35, IGF1R, INSR, KDR, KIT, MET, MIF, MMP2, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCB, PRKCD, PRKCE, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TRPV1 |
3.31438 |
|
[BP] GO:0045980 |
None
|
DRD2, HTR1B, HTR1E, OPRM1, PPARA, PRKCA |
3.31438 |
|
[BP] GO:0009820 |
alkaloid metabolic process
|
CYP1A2, CYP2D6, CYP3A4 |
3.28841 |
|
[BP] GO:0010511 |
None
|
HTR2A, HTR2B, HTR2C |
3.28841 |
|
[BP] GO:0002793 |
None
|
ACHE, ADORA1, DRD2, EGFR, HCAR2, HTR2B, MIF, MMP12, PRKCE, SRC |
3.28841 |
|
[BP] GO:0045766 |
positive regulation of angiogenesis
|
CYP1B1, F3, KDR, PRKCA, PRKCB, PTGS2, TEK, TERT |
3.26937 |
|
[BP] GO:0015844 |
None
|
DRD1, SLC22A1, SLC22A2, SLC22A3 |
3.26076 |
|
[BP] GO:0071383 |
None
|
AKR1C3, AR, EGFR, FLT3, NR3C1, SRC |
3.25185 |
|
[BP] GO:0043393 |
regulation of protein binding
|
APP, AURKB, BCL2, MET, MMP9, PPARA, PRKCD, SRC, TERT |
3.23504 |
|
[BP] GO:0050999 |
None
|
CNR1, CNR2, EGFR, HTR2B, TERT |
3.23504 |
|
[BP] GO:0007346 |
regulation of mitotic cell cycle
|
APEX1, APP, AURKB, BCL2, CDC25B, CYP1A1, DUSP3, EGFR, HSPA1A, INSR, PIM1, PRKCA, SMAD3, TERT, TNKS, TOP2A |
3.23459 |
|
[BP] GO:1904951 |
positive regulation of establishment of protein localization
|
ACHE, APP, BCL2, DRD2, EGFR, HCAR2, HTR2B, MIF, MMP12, PRKCD, PRKCE, PTGS2, SMAD3, SRC |
3.22474 |
|
[BP] GO:0051282 |
None
|
DRD1, DRD2, HTR2A, HTR2B, HTR2C, PRKCE, TRPV1 |
3.21672 |
|
[BP] GO:0051701 |
interaction with host
|
AXL, EGFR, HSPA1A, HTR2A, INSR, MET, SMAD3, SRC |
3.19657 |
|
[BP] GO:0045934 |
None
|
APEX1, AR, AURKB, DNMT1, DRD2, DYRK1A, ESR1, ESR2, ESRRA, FABP4, HSPA1A, HTR1B, HTR1E, MMP12, NR3C1, OPRM1, PPARA, PRKCA, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TRPV1 |
3.19657 |
|
[BP] GO:0001503 |
ossification
|
ALOX15, ALPL, BCL2, EGFR, MMP2, MMP9, TEK |
3.19441 |
|
[BP] GO:0060401 |
None
|
DRD2, HTR2A, HTR2B, HTR2C, PRKCE, TRPV1 |
3.19401 |
|
[BP] GO:0033554 |
cellular response to stress
|
AKR1B1, AKR1C3, ALOX15, APEX1, AXL, BCL2, CA2, CA9, CYP1B1, EGFR, HSPA1A, MIF, MMP9, NUAK1, OPRD1, OPRM1, POLA1, POLB, PRKCD, PRKCE, PTGS2, PTPN1, SRC, TERT, TOP2A, TRPV1 |
3.18978 |
|
[BP] GO:0042698 |
ovulation cycle
|
AXL, EGFR, OPRK1, OPRM1 |
3.18969 |
|
[BP] GO:1904707 |
positive regulation of vascular smooth muscle cell proliferation
|
HTR1B, MMP2, MMP9, TERT |
3.18969 |
|
[BP] GO:0050995 |
None
|
ADORA1, CNR1, HCAR2, PDE3B |
3.18969 |
|
[BP] GO:0001101 |
response to acid chemical
|
AKR1B1, AKR1C3, DNMT1, EGFR, FABP3, HSD17B2, KDR, MMP2, PRKCE, PTGS2, SRC |
3.18588 |
|
[BP] GO:0006810 |
None
|
ABCB1, ACHE, ADORA1, AKR1C3, ALOX15, ALOX5, APP, AR, AXL, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, DRD1, DRD2, F10, FABP3, HSPA1A, HTR1B, HTR2A, HTR2B, HTR2C, KIT, MIF, MMP12, MMP9, OPRD1, OPRM1, PPARA, PRKCB, PRKCD, PRKCE, SIGMAR1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SOAT1, SOAT2, SRC, TNKS, TRPV1, XDH |
3.18376 |
|
[BP] GO:0050728 |
negative regulation of inflammatory response
|
ADORA1, CNR2, CYP19A1, PPARA, PRKCD, SMAD3, TEK |
3.17859 |
|
[BP] GO:0070201 |
None
|
ACHE, APP, BCL2, CNR1, DRD2, EGFR, HCAR2, HTR2B, MIF, MMP12, OPRM1, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC |
3.17859 |
|
[BP] GO:0030155 |
regulation of cell adhesion
|
ALOX15, BCL2, CYP1B1, DUSP3, KDR, NUAK1, PDE3B, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCE, SMAD3, SRC, TEK |
3.16865 |
|
[BP] GO:0050727 |
regulation of inflammatory response
|
ADORA1, CNR1, CNR2, CYP19A1, EGFR, ESR1, FABP4, PPARA, PRKCD, PTGS2, SMAD3, TEK |
3.15397 |
|
[BP] GO:2001234 |
negative regulation of apoptotic signaling pathway
|
AR, BCL2, HSPA1A, MIF, MMP9, PTGS2, PTPN1, SRC, TERT |
3.15335 |
|
[BP] GO:0030518 |
intracellular steroid hormone receptor signaling pathway
|
AR, ESR1, ESR2, NR3C1, PGR, SRC |
3.14146 |
|
[BP] GO:0018958 |
None
|
AKR1B1, BCL2, DRD1, DRD2, HTR1A, TYR |
3.14146 |
|
[BP] GO:0044597 |
None
|
AKR1B1, AKR1B10, AKR1C3 |
3.11564 |
|
[BP] GO:0044598 |
None
|
AKR1B1, AKR1B10, AKR1C3 |
3.11564 |
|
[BP] GO:0030638 |
None
|
AKR1B1, AKR1B10, AKR1C3 |
3.11564 |
|
[BP] GO:0050433 |
None
|
CNR1, DRD2, HTR1B, HTR2A, OPRK1 |
3.11564 |
|
[BP] GO:0038083 |
peptidyl-tyrosine autophosphorylation
|
EGFR, IGF1R, INSR, KDR, SRC |
3.11564 |
|
[BP] GO:0048608 |
reproductive structure development
|
AKR1C3, AR, AXL, BCL2, CYP19A1, ESR1, HSD17B2, INSR, KIT, SRC |
3.10342 |
|
[BP] GO:0050678 |
None
|
AR, EGFR, F3, HTR2B, KDR, MMP12, PGR, PRKCA, SMAD3, TEK, XDH |
3.10118 |
|
[BP] GO:0009056 |
catabolic process
|
ACHE, ADORA1, AKR1B10, AKR1C3, AOX1, AURKB, BACE1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP2D6, CYP3A4, FABP3, FABP4, FUT7, HSPA1A, MMP1, MMP12, MMP2, MMP9, PDE10A, PDE3A, PDE3B, PIK3CB, SRC, XDH |
3.09629 |
|
[BP] GO:1901342 |
regulation of vasculature development
|
CYP1B1, F3, KDR, KIT, PDE3B, PRKCA, PRKCB, PTGS2, TEK, TERT, XDH |
3.09076 |
|
[BP] GO:0030815 |
None
|
DRD2, HTR1B, HTR1E, OPRM1, PRKCA |
3.07461 |
|
[BP] GO:0043065 |
positive regulation of apoptotic process
|
AKR1C3, BCL2, CNR1, CYP1B1, F3, HCAR2, MMP9, PIK3CB, PRKCD, PTGS2, SMAD3, SRC, TOP2A, TRPV1, XDH |
3.07122 |
|
[BP] GO:1901655 |
None
|
AKR1B1, AR, EGFR, NR3C1, PRKCE, SRC |
3.05768 |
|
[BP] GO:0008210 |
estrogen metabolic process
|
CYP19A1, CYP1B1, HSD17B1, HSD17B2 |
3.05246 |
|
[BP] GO:0042391 |
None
|
ADORA1, APP, BCL2, CNR1, CNR2, DRD1, GPR35, KDR, OPRD1, OPRM1, SRC, TRPV1 |
3.03902 |
|
[BP] GO:0050878 |
regulation of body fluid levels
|
ADORA1, AKR1B1, DRD2, F10, F3, MET, OPRK1, PRKCA, PRKCD, PRKCE, SLC22A2, XDH |
3.03902 |
|
[BP] GO:0010518 |
positive regulation of phospholipase activity
|
EGFR, ESR1, HTR2A, HTR2B, KIT |
3.03543 |
|
[BP] GO:0044070 |
regulation of anion transport
|
ABCB1, ADORA1, CA2, CA7, MIF, PRKCD |
3.032 |
|
[BP] GO:0043068 |
positive regulation of programmed cell death
|
AKR1C3, BCL2, CNR1, CYP1B1, F3, HCAR2, MMP9, PIK3CB, PRKCD, PTGS2, SMAD3, SRC, TOP2A, TRPV1, XDH |
3.02853 |
|
[BP] GO:0032496 |
response to lipopolysaccharide
|
ALPL, AXL, CNR1, CNR2, CYP1A1, CYP1A2, OPRK1, OPRM1, PTGS2, SRC |
3.02007 |
|
[BP] GO:0010638 |
positive regulation of organelle organization
|
ALOX15, AURKB, BCL2, DNMT1, HSPA1A, INSR, KDR, MET, MMP9, PRKCE, SMAD3, SRC, TEK, TNKS, TNKS2 |
3.0147 |
|
[BP] GO:0030800 |
None
|
DRD2, HTR1B, HTR1E, OPRM1, PRKCA |
2.99887 |
|
[BP] GO:0072523 |
None
|
AOX1, PDE10A, PDE3A, PDE3B, XDH |
2.99887 |
|
[BP] GO:0006928 |
movement of cell or subcellular component
|
APP, AXL, CNR2, CYP1B1, DRD1, DRD2, EGFR, FUT7, HTR2B, HTR6, KDR, KIT, MIF, MMP1, MMP12, MMP9, PIK3CA, PIK3CB, PRKCA, PRKCD, PTGS2, SRC, TEK, TUBB3 |
2.99535 |
|
[BP] GO:0031667 |
response to nutrient levels
|
AKR1C3, ALPL, BCL2, CNR1, CYP1A1, EGFR, HSD11B2, OPRM1, PTGS2, SRC, TRPV1, TYR |
2.99535 |
|
[BP] GO:0050776 |
regulation of immune response
|
ALOX15, BCL2, CNR1, DRD2, DUSP3, ESR1, HSPA1A, KIT, MIF, MMP12, MMP2, PIK3CA, PIK3CB, PRKCB, PRKCD, PRKCE, PTPN1, PTPRS, SMAD3, SRC |
2.9914 |
|
[BP] GO:0071241 |
cellular response to inorganic substance
|
AKR1C3, ALOX15, CYP1A1, CYP1A2, EGFR, FABP4, MMP9, PTGS2 |
2.97105 |
|
[BP] GO:0019752 |
carboxylic acid metabolic process
|
AKR1C3, ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, FABP3, GLO1, MIF, PIM1, PPARA, PTGS1, PTGS2, TYR |
2.97 |
|
[BP] GO:0030647 |
None
|
AKR1B1, AKR1B10, AKR1C3 |
2.96874 |
|
[BP] GO:0051223 |
None
|
ACHE, APP, CNR1, DRD2, EGFR, HCAR2, HTR2B, MIF, MMP12, OPRM1, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC |
2.94087 |
|
[BP] GO:0031329 |
regulation of cellular catabolic process
|
APEX1, BCL2, CNR1, ESRRB, HSPA1A, HTR2A, HTR2B, INSR, KDR, MET, PIK3CA, PIK3CB, PPARA, PRKCA, PRKCD, PRKCG, PTPN1 |
2.93471 |
|
[BP] GO:0051222 |
positive regulation of protein transport
|
ACHE, APP, DRD2, EGFR, HCAR2, HTR2B, MIF, MMP12, PRKCD, PRKCE, PTGS2, SMAD3, SRC |
2.93283 |
|
[BP] GO:0006693 |
None
|
AKR1C3, MIF, PTGS1, PTGS2 |
2.93283 |
|
[BP] GO:0006692 |
None
|
AKR1C3, MIF, PTGS1, PTGS2 |
2.93283 |
|
[BP] GO:0051480 |
regulation of cytosolic calcium ion concentration
|
DRD1, DRD2, ESR1, GPR35, HTR2A, HTR2B, HTR2C, PRKCE, SMAD3, TRPV1 |
2.93283 |
|
[BP] GO:1903428 |
positive regulation of reactive oxygen species biosynthetic process
|
EGFR, INSR, PTGS2, SMAD3, TRPV1 |
2.93148 |
|
[BP] GO:0010676 |
None
|
ESRRB, INSR, PPARA, PRKCE, SRC |
2.93148 |
|
[BP] GO:0050679 |
None
|
AR, EGFR, F3, HTR2B, KDR, MMP12, PRKCA, TEK |
2.93034 |
|
[BP] GO:0048660 |
regulation of smooth muscle cell proliferation
|
AKR1B1, EGFR, HTR1B, MMP2, MMP9, PTGS2, TERT |
2.92099 |
|
[BP] GO:0043412 |
macromolecule modification
|
ALPL, APEX1, APP, AR, AURKB, AXL, BCL2, CDC25B, CSNK2A1, DNMT1, DRD1, DUSP3, DYRK1A, EGFR, ESR1, F10, FLT3, FUT7, HTR2B, IGF1R, INSR, KDR, KIT, MET, NR3C1, NUAK1, PIK3CA, PIM1, POLB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, PTPRS, SENP6, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
2.8947 |
|
[BP] GO:0071902 |
positive regulation of protein serine/threonine kinase activity
|
ADORA1, EGFR, FLT3, HTR2A, HTR2B, INSR, KIT, MIF, PIK3CB, PTPN1, SRC |
2.89099 |
|
[BP] GO:1901654 |
None
|
AKR1B1, AR, CA9, CSNK2A1, EGFR, NR3C1, PRKCE, SRC |
2.88248 |
|
[BP] GO:1900182 |
positive regulation of protein localization to nucleus
|
APP, EGFR, PRKCD, PTGS2, SMAD3, SRC, TERT |
2.88248 |
|
[BP] GO:0046683 |
response to organophosphorus
|
APEX1, APP, PDE3A, PTGS2, TEK, TRPV1, TYR |
2.88248 |
|
[BP] GO:0007626 |
None
|
APP, DRD1, DRD2, HTR2C, OPRD1, OPRK1, OPRM1, PRKCE |
2.86662 |
|
[BP] GO:0033135 |
regulation of peptidyl-serine phosphorylation
|
APP, BCL2, EGFR, MIF, OPRD1, PIK3CA, PTGS2 |
2.86269 |
|
[BP] GO:0033555 |
multicellular organismal response to stress
|
BCL2, DRD1, HTR1A, HTR2C, PRKCG |
2.86067 |
|
[BP] GO:0009889 |
regulation of biosynthetic process
|
ADORA3, AKR1C3, APEX1, APP, AR, AURKB, BCL2, CA9, CSNK2A1, CYP1B1, DNMT1, DRD1, DRD2, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, GLO1, HSPA1A, HTR1B, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, MMP12, NR3C1, NR3C2, OPRD1, OPRM1, PGR, PIM1, POLA1, PPARA, PRKCA, PRKCB, PRKCD, PTGS2, RORC, SMAD3, SOAT1, SRC, TERT, TNKS, TNKS2, TOP2A, TRPV1 |
2.85449 |
|
[BP] GO:0009314 |
response to radiation
|
APP, AURKB, BCL2, DRD1, DRD2, EGFR, KIT, OPRK1, OPRM1, POLB, PTGS2, TYR |
2.84719 |
|
[BP] GO:1903532 |
None
|
ACHE, CYP19A1, DRD2, EGFR, HCAR2, HTR2B, MIF, MMP12, OPRK1, PRKCE, SRC |
2.84301 |
|
[BP] GO:0071396 |
cellular response to lipid
|
AKR1C3, AR, AXL, EGFR, ESR1, FLT3, NR3C1, OPRK1, PRKCE, RORC, SRC |
2.84301 |
|
[BP] GO:0050714 |
None
|
ACHE, DRD2, EGFR, HCAR2, HTR2B, MIF, MMP12, PRKCE, SRC |
2.83773 |
|
[BP] GO:2001225 |
regulation of chloride transport
|
ABCB1, CA2, CA7 |
2.83773 |
|
[BP] GO:0097267 |
omega-hydroxylase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1 |
2.83773 |
|
[BP] GO:0050708 |
None
|
ACHE, CNR1, DRD2, EGFR, HCAR2, HTR2B, MIF, MMP12, OPRM1, PRKCA, PRKCE, SRC |
2.832 |
|
[BP] GO:0009187 |
None
|
HTR2B, HTR2C, PDE10A, PDE3A, PDE3B |
2.82953 |
|
[BP] GO:0032768 |
None
|
CNR1, CNR2, EGFR, HTR2B, TERT |
2.82953 |
|
[BP] GO:0097164 |
None
|
ACHE, AKR1B1, AKR1B10, AKR1C3, CSNK2A1, DRD1, DRD2, HTR1A |
2.82543 |
|
[BP] GO:0033032 |
regulation of myeloid cell apoptotic process
|
BCL2, HCAR2, MIF, PIK3CB |
2.82185 |
|
[BP] GO:0002237 |
response to molecule of bacterial origin
|
ALPL, AXL, CNR1, CNR2, CYP1A1, CYP1A2, OPRK1, OPRM1, PTGS2, SRC |
2.8149 |
|
[BP] GO:0050877 |
None
|
ADORA1, APP, CNR1, CNR2, CYP1B1, DRD1, DRD2, EGFR, HTR2A, INSR, KIT, OPRD1, OPRK1, OPRM1, PRKCG, PTGS2, TRPV1, TYR |
2.78199 |
|
[BP] GO:0007612 |
None
|
APP, DRD1, DRD2, INSR, KIT, OPRK1, PTGS2 |
2.77184 |
|
[BP] GO:0006636 |
unsaturated fatty acid biosynthetic process
|
ALOX15, MIF, PTGS1, PTGS2 |
2.76358 |
|
[BP] GO:0045428 |
regulation of nitric oxide biosynthetic process
|
EGFR, INSR, PTGS2, SMAD3, TRPV1 |
2.76002 |
|
[BP] GO:0048732 |
gland development
|
AR, BCL2, CSNK2A1, CYP19A1, EGFR, INSR, PIK3CA, SMAD3, TYR |
2.75733 |
|
[BP] GO:0032409 |
None
|
ABCB1, APP, BCL2, DRD2, GPR35, MMP9, OPRM1, PRKCD, PRKCE |
2.75733 |
|
[BP] GO:0007208 |
None
|
HTR2A, HTR2C |
2.75733 |
|
[BP] GO:0031635 |
None
|
OPRK1, OPRM1 |
2.75733 |
|
[BP] GO:0016488 |
None
|
AKR1B10, AKR1C3 |
2.75733 |
|
[BP] GO:0016487 |
None
|
AKR1B10, AKR1C3 |
2.75733 |
|
[BP] GO:0035408 |
None
|
PRKCA, PRKCB |
2.75733 |
|
[BP] GO:0016107 |
None
|
AKR1B10, AKR1C3 |
2.75733 |
|
[BP] GO:0009115 |
None
|
AOX1, XDH |
2.75733 |
|
[BP] GO:0006714 |
None
|
AKR1B10, AKR1C3 |
2.75733 |
|
[BP] GO:0006286 |
base-excision repair, base-free sugar-phosphate removal
|
APEX1, POLB |
2.75733 |
|
[BP] GO:0030258 |
lipid modification
|
CYP1A1, CYP3A4, EGFR, KIT, MET, PIK3CA, PIK3CB, SOAT1, SOAT2 |
2.75172 |
|
[BP] GO:0010810 |
regulation of cell-substrate adhesion
|
ALOX15, BCL2, KDR, PIK3CB, PRKCE, SMAD3, SRC, TEK |
2.74898 |
|
[BP] GO:0032868 |
None
|
FABP3, HSD11B2, INSR, OPRK1, PDE3B, PPARA, SRC |
2.73263 |
|
[BP] GO:0051384 |
response to glucocorticoid
|
ALPL, BCL2, EGFR, FLT3, HSD11B2, NR3C1, PTGS2 |
2.73263 |
|
[BP] GO:0002031 |
None
|
DRD2, HTR1B, HTR2B |
2.73263 |
|
[BP] GO:0002320 |
lymphoid progenitor cell differentiation
|
BCL2, FLT3, KIT |
2.73263 |
|
[BP] GO:0060736 |
prostate gland growth
|
AR, CYP19A1, ESR1 |
2.73263 |
|
[BP] GO:0031326 |
regulation of cellular biosynthetic process
|
ADORA3, AKR1C3, APEX1, APP, AR, AURKB, BCL2, CA9, CSNK2A1, CYP1B1, DNMT1, DRD1, DRD2, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, GLO1, HSPA1A, HTR1B, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KIT, MET, MMP12, NR3C1, NR3C2, OPRD1, OPRM1, PGR, PIM1, POLA1, PPARA, PRKCA, PRKCB, PRKCD, PTGS2, RORC, SMAD3, SOAT1, SRC, TERT, TNKS, TNKS2, TOP2A, TRPV1 |
2.73166 |
|
[BP] GO:0019219 |
regulation of nucleobase-containing compound metabolic process
|
ADORA3, APEX1, APP, AR, AURKB, CA9, CSNK2A1, CYP1B1, DNMT1, DRD1, DRD2, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP4, GLO1, HSPA1A, HTR1B, HTR1E, HTR2A, IGF1R, INSR, KIT, MET, MMP12, NR3C1, NR3C2, OPRD1, OPRM1, PGR, PIK3CA, PIM1, POLA1, PPARA, PRKCA, PRKCB, PRKCD, PRKCG, PTPN1, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A, TRPV1 |
2.73134 |
|
[BP] GO:0035265 |
organ growth
|
AR, BCL2, CYP19A1, ESR1 |
2.73134 |
|
[BP] GO:0002209 |
None
|
BCL2, DRD1, HTR1A, HTR2C |
2.73134 |
|
[BP] GO:0001662 |
None
|
BCL2, DRD1, HTR1A, HTR2C |
2.73134 |
|
[BP] GO:0043552 |
positive regulation of phosphatidylinositol 3-kinase activity
|
FLT3, KIT, SRC, TEK |
2.73134 |
|
[BP] GO:0010942 |
positive regulation of cell death
|
AKR1C3, BCL2, CNR1, CYP1B1, F3, HCAR2, MMP9, PIK3CB, PRKCD, PTGS2, SMAD3, SRC, TOP2A, TRPV1, XDH |
2.72606 |
|
[BP] GO:0003014 |
None
|
ADORA1, AKR1B1, AKR1C3, BCL2, DRD2, HSD11B2 |
2.71904 |
|
[BP] GO:0044267 |
cellular protein metabolic process
|
ALPL, APP, AR, AURKB, AXL, BACE1, BCL2, CDC25B, CSNK2A1, DRD1, DUSP3, DYRK1A, EGFR, ESR1, F10, FLT3, FUT7, HTR2B, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP2, NUAK1, PIK3CA, PIM1, POLB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, PTPRS, SENP6, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
2.71904 |
|
[BP] GO:0034502 |
protein localization to chromosome
|
AURKB, ESR1, TERT, TNKS, TNKS2 |
2.71904 |
|
[BP] GO:0010517 |
regulation of phospholipase activity
|
EGFR, ESR1, HTR2A, HTR2B, KIT |
2.71904 |
|
[BP] GO:0070988 |
demethylation
|
APEX1, CYP1A1, CYP1A2, CYP2D6, CYP3A4 |
2.71904 |
|
[BP] GO:0007204 |
positive regulation of cytosolic calcium ion concentration
|
DRD1, DRD2, ESR1, GPR35, HTR2A, HTR2B, HTR2C, PRKCE, TRPV1 |
2.69855 |
|
[BP] GO:0016101 |
None
|
AKR1B10, AKR1C3, CYP1A1, CYP1B1, EGFR, PDE3A |
2.69691 |
|
[BP] GO:0007584 |
response to nutrient
|
AKR1C3, ALPL, CNR1, CYP1A1, EGFR, PTGS2, TRPV1, TYR |
2.68444 |
|
[BP] GO:0042220 |
None
|
CNR1, DRD2, HTR1B, OPRM1 |
2.68225 |
|
[BP] GO:0071276 |
cellular response to cadmium ion
|
AKR1C3, CYP1A2, EGFR, MMP9 |
2.68225 |
|
[BP] GO:0042752 |
None
|
ADORA1, DRD2, PPARA, PRKCG, RORC, TOP2A |
2.67475 |
|
[BP] GO:0070301 |
cellular response to hydrogen peroxide
|
AKR1B1, APEX1, AXL, CYP1B1, PRKCD |
2.65457 |
|
[BP] GO:0048015 |
phosphatidylinositol-mediated signaling
|
HTR2A, HTR2B, IGF1R, PIK3CA, PIK3CB |
2.65457 |
|
[BP] GO:0032147 |
activation of protein kinase activity
|
ADORA1, DRD2, EGFR, INSR, KIT, PIK3CA, PIK3CB, PRKCD, PTPN1, SRC |
2.64204 |
|
[BP] GO:0022029 |
None
|
DRD1, DRD2, EGFR, HTR6 |
2.63194 |
|
[BP] GO:0042596 |
None
|
BCL2, DRD1, HTR1A, HTR2C |
2.63194 |
|
[BP] GO:2001233 |
regulation of apoptotic signaling pathway
|
AR, BCL2, HSPA1A, MIF, MMP9, PRKCD, PTGS2, PTPN1, SMAD3, SRC, TERT |
2.63194 |
|
[BP] GO:0042738 |
exogenous drug catabolic process
|
CYP1A2, CYP2A6, CYP3A4 |
2.63194 |
|
[BP] GO:0015697 |
None
|
SLC22A1, SLC22A2, SLC22A3 |
2.63194 |
|
[BP] GO:0045759 |
None
|
CNR1, CNR2, GPR35 |
2.63194 |
|
[BP] GO:0070989 |
oxidative demethylation
|
CYP1A2, CYP2D6, CYP3A4 |
2.63194 |
|
[BP] GO:0060193 |
positive regulation of lipase activity
|
EGFR, ESR1, HTR2A, HTR2B, KIT |
2.62813 |
|
[BP] GO:0014074 |
response to purine-containing compound
|
APEX1, APP, PDE3A, PTGS2, TEK, TRPV1, TYR |
2.62355 |
|
[BP] GO:0010605 |
negative regulation of macromolecule metabolic process
|
APEX1, APP, AR, AURKB, CSNK2A1, DNMT1, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, FABP4, HSPA1A, IGF1R, KDR, MIF, MMP12, MMP9, NR3C1, OPRD1, PGR, PPARA, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TRPV1, XDH |
2.61972 |
|
[BP] GO:0006464 |
cellular protein modification process
|
ALPL, APP, AR, AURKB, AXL, BCL2, CDC25B, CSNK2A1, DRD1, DUSP3, DYRK1A, EGFR, ESR1, F10, FLT3, FUT7, HTR2B, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIM1, POLB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, PTPRS, SENP6, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
2.61604 |
|
[BP] GO:0036211 |
protein modification process
|
ALPL, APP, AR, AURKB, AXL, BCL2, CDC25B, CSNK2A1, DRD1, DUSP3, DYRK1A, EGFR, ESR1, F10, FLT3, FUT7, HTR2B, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIM1, POLB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, PTPRS, SENP6, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
2.61604 |
|
[BP] GO:0051828 |
entry into other organism involved in symbiotic interaction
|
AXL, EGFR, HSPA1A, HTR2A, MET, SRC |
2.61604 |
|
[BP] GO:0030260 |
entry into host cell
|
AXL, EGFR, HSPA1A, HTR2A, MET, SRC |
2.61604 |
|
[BP] GO:0051806 |
entry into cell of other organism involved in symbiotic interaction
|
AXL, EGFR, HSPA1A, HTR2A, MET, SRC |
2.61604 |
|
[BP] GO:0044409 |
entry into host
|
AXL, EGFR, HSPA1A, HTR2A, MET, SRC |
2.61604 |
|
[BP] GO:0001525 |
angiogenesis
|
CYP1B1, KDR, MMP2, PDE3B, PIK3CA, PIK3CB, PRKCA, PTGS2, TEK |
2.61269 |
|
[BP] GO:0090218 |
positive regulation of lipid kinase activity
|
FLT3, KIT, SRC, TEK |
2.59217 |
|
[BP] GO:0010907 |
None
|
ESRRB, INSR, PPARA, SRC |
2.59217 |
|
[BP] GO:0001952 |
regulation of cell-matrix adhesion
|
BCL2, KDR, PIK3CB, SMAD3, SRC, TEK |
2.57462 |
|
[BP] GO:0051090 |
regulation of DNA binding transcription factor activity
|
ADORA3, APP, AR, CYP1B1, ESR1, ESR2, HSPA1A, KIT, OPRD1, PIM1, PRKCB |
2.57462 |
|
[BP] GO:0051052 |
regulation of DNA metabolic process
|
AURKB, DNMT1, EGFR, IGF1R, INSR, PIK3CA, PRKCD, PRKCG, SRC, TNKS, TNKS2 |
2.57462 |
|
[BP] GO:0048017 |
inositol lipid-mediated signaling
|
HTR2A, HTR2B, IGF1R, PIK3CA, PIK3CB |
2.57396 |
|
[BP] GO:0009266 |
None
|
ADORA1, HSPA1A, HTR1B, HTR2A, HTR2B, PTGS2, TRPV1 |
2.56181 |
|
[BP] GO:0071456 |
cellular response to hypoxia
|
BCL2, OPRD1, PRKCE, PTGS2, SRC, TERT |
2.55328 |
|
[BP] GO:0051930 |
None
|
ADORA1, OPRD1, OPRK1, OPRM1 |
2.54551 |
|
[BP] GO:0051931 |
None
|
ADORA1, OPRD1, OPRK1, OPRM1 |
2.54551 |
|
[BP] GO:0006703 |
estrogen biosynthetic process
|
CYP19A1, HSD17B1, HSD17B2 |
2.53853 |
|
[BP] GO:0032230 |
positive regulation of synaptic transmission, GABAergic
|
CA2, CA7, PRKCE |
2.53853 |
|
[BP] GO:0001516 |
None
|
MIF, PTGS1, PTGS2 |
2.53853 |
|
[BP] GO:0046457 |
None
|
MIF, PTGS1, PTGS2 |
2.53853 |
|
[BP] GO:0007613 |
None
|
CNR1, DRD1, DRD2, HTR2A, INSR, PTGS2 |
2.53483 |
|
[BP] GO:0003012 |
None
|
ADORA1, DRD1, DRD2, HTR1D, HTR2A, HTR2B, HTR7, PIK3CA, TRPV1 |
2.52198 |
|
[BP] GO:0044236 |
multicellular organism metabolic process
|
AKR1C3, MMP1, MMP12, MMP2, MMP9, TRPV1 |
2.51395 |
|
[BP] GO:0043436 |
oxoacid metabolic process
|
AKR1C3, ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, FABP3, GLO1, MIF, PIM1, PPARA, PTGS1, PTGS2, TYR |
2.51283 |
|
[BP] GO:0045595 |
regulation of cell differentiation
|
APP, AR, AXL, BCL2, CA2, CNR1, DRD2, EGFR, ESRRA, ESRRB, HTR2A, HTR2C, KDR, KIT, OPRM1, PDE3A, PPARA, PRKCA, PRKCB, PTGS2, PTPRS, RORC, SMAD3, TERT, TRPV1, XDH |
2.50961 |
|
[BP] GO:1901653 |
cellular response to peptide
|
AKR1B1, APEX1, APP, IGF1R, INSR, PDE3B, PRKCD, SRC |
2.49059 |
|
[BP] GO:0040014 |
regulation of multicellular organism growth
|
APP, BCL2, DRD2, PIK3CA, TNKS2 |
2.48976 |
|
[BP] GO:1900076 |
regulation of cellular response to insulin stimulus
|
ESRRA, PRKCB, PRKCD, PTPN1, SRC |
2.48976 |
|
[BP] GO:0008406 |
gonad development
|
AKR1C3, BCL2, CYP19A1, ESR1, INSR, KIT |
2.47354 |
|
[BP] GO:0016042 |
lipid catabolic process
|
ADORA1, AKR1B10, AKR1C3, CYP19A1, CYP1A2, CYP1B1, CYP3A4, FABP3, FABP4 |
2.45441 |
|
[BP] GO:0060065 |
uterus development
|
CYP19A1, ESR1, SRC |
2.4465 |
|
[BP] GO:0006198 |
None
|
PDE10A, PDE3A, PDE3B |
2.4465 |
|
[BP] GO:0046486 |
glycerolipid metabolic process
|
ACHE, ALOX15, CSNK2A1, DRD2, EGFR, FABP3, FABP4, KIT, MET, PIK3CA, PIK3CB |
2.43691 |
|
[BP] GO:2001242 |
regulation of intrinsic apoptotic signaling pathway
|
BCL2, HSPA1A, MIF, MMP9, PTGS2, PTPN1, SRC |
2.43691 |
|
[BP] GO:0042180 |
None
|
AKR1B1, AKR1B10, AKR1C3, CYP19A1, GLO1 |
2.43586 |
|
[BP] GO:0006082 |
organic acid metabolic process
|
AKR1C3, ALOX15, ALOX5, CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, FABP3, GLO1, MIF, PIM1, PPARA, PTGS1, PTGS2, TYR |
2.42641 |
|
[BP] GO:0002683 |
negative regulation of immune system process
|
ADORA1, ALOX15, AXL, CNR1, CNR2, CYP19A1, DRD2, DUSP3, MIF, MMP12, PTPRS |
2.42166 |
|
[BP] GO:0032467 |
None
|
AURKB, CDC25B, DRD2, PRKCE |
2.41736 |
|
[BP] GO:0036294 |
cellular response to decreased oxygen levels
|
BCL2, OPRD1, PRKCE, PTGS2, SRC, TERT |
2.41736 |
|
[BP] GO:0006936 |
None
|
DRD1, DRD2, HTR1D, HTR2A, HTR2B, HTR7, PIK3CA, TRPV1 |
2.41736 |
|
[BP] GO:0090068 |
positive regulation of cell cycle process
|
APEX1, APP, AURKB, CDC25B, CYP1A1, DRD2, INSR, PRKCE, TERT |
2.41576 |
|
[BP] GO:0010632 |
regulation of epithelial cell migration
|
KDR, MET, MMP9, PRKCA, PRKCE, PTGS2, SRC, TEK |
2.40466 |
|
[BP] GO:0008306 |
None
|
APP, DRD1, DRD2, KIT, OPRK1 |
2.38314 |
|
[BP] GO:0015695 |
None
|
SLC22A1, SLC22A2, SLC22A3, SLC47A1 |
2.37618 |
|
[BP] GO:0019637 |
organophosphate metabolic process
|
ACHE, ALOX15, CSNK2A1, DRD2, EGFR, HSPA1A, HTR2B, HTR2C, KIT, MET, PDE10A, PDE3A, PDE3B, PIK3CA, PIK3CB, PTGS2, XDH |
2.37618 |
|
[BP] GO:0050965 |
None
|
ADORA1, HTR2A, TRPV1 |
2.36676 |
|
[BP] GO:0050961 |
None
|
ADORA1, HTR2A, TRPV1 |
2.36676 |
|
[BP] GO:0070198 |
None
|
TERT, TNKS, TNKS2 |
2.36676 |
|
[BP] GO:0044089 |
positive regulation of cellular component biogenesis
|
ALOX15, ESR1, HSPA1A, KDR, KIT, MET, MMP1, PRKCA, PRKCE, SMAD3, SRC, TEK |
2.36676 |
|
[BP] GO:0048010 |
vascular endothelial growth factor receptor signaling pathway
|
AXL, KDR, PIK3CA, PIK3CB, SRC |
2.36676 |
|
[BP] GO:0030100 |
regulation of endocytosis
|
ALOX15, APP, AXL, DRD2, PIK3CB, PRKCG, PTPN1, SRC |
2.36676 |
|
[BP] GO:0034435 |
None
|
SOAT1, SOAT2 |
2.36676 |
|
[BP] GO:0060748 |
None
|
AR, PGR |
2.36676 |
|
[BP] GO:0098502 |
DNA dephosphorylation
|
APEX1, POLB |
2.36676 |
|
[BP] GO:0009822 |
alkaloid catabolic process
|
CYP2D6, CYP3A4 |
2.36676 |
|
[BP] GO:0034433 |
None
|
SOAT1, SOAT2 |
2.36676 |
|
[BP] GO:0034434 |
None
|
SOAT1, SOAT2 |
2.36676 |
|
[BP] GO:0046110 |
None
|
AOX1, XDH |
2.36676 |
|
[BP] GO:0032849 |
positive regulation of cellular pH reduction
|
CA2, CA7 |
2.36676 |
|
[BP] GO:0033602 |
None
|
CNR1, DRD2 |
2.36676 |
|
[BP] GO:0016095 |
None
|
AKR1B10, AKR1C3 |
2.36676 |
|
[BP] GO:0071702 |
None
|
ABCB1, ADORA1, AKR1C3, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, DRD1, DRD2, FABP3, MMP12, OPRD1, PPARA, PRKCB, SIGMAR1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SOAT1, SOAT2, TNKS, TRPV1 |
2.35336 |
|
[BP] GO:0038128 |
None
|
EGFR, PIK3CA, PRKCA, SRC |
2.35029 |
|
[BP] GO:1904705 |
regulation of vascular smooth muscle cell proliferation
|
HTR1B, MMP2, MMP9, TERT |
2.35029 |
|
[BP] GO:0045597 |
positive regulation of cell differentiation
|
APP, AR, AXL, BCL2, CA2, CNR1, DRD2, HTR2A, HTR2C, KDR, KIT, OPRM1, PDE3A, PRKCA, PTGS2, SMAD3, TERT |
2.34895 |
|
[BP] GO:0002009 |
morphogenesis of an epithelium
|
AR, BCL2, CA2, CA9, EGFR, ESR1, MET, SMAD3, SRC |
2.34466 |
|
[BP] GO:0030814 |
None
|
DRD1, DRD2, HTR1B, HTR1E, OPRM1, PRKCA |
2.33706 |
|
[BP] GO:0048534 |
hematopoietic or lymphoid organ development
|
BCL2, FLT3, KDR, KIT, POLB, TEK, TYR |
2.3199 |
|
[BP] GO:0046890 |
None
|
AKR1C3, FABP3, HTR2A, HTR2B, HTR2C, PRKCD, PTGS2 |
2.3199 |
|
[BP] GO:0009416 |
response to light stimulus
|
APP, AURKB, BCL2, DRD1, DRD2, EGFR, KIT, PTGS2, TYR |
2.31468 |
|
[BP] GO:0050900 |
leukocyte migration
|
CNR2, FUT7, KIT, MIF, MMP1, MMP9, PIK3CA, PIK3CB, SRC, TEK |
2.31468 |
|
[BP] GO:2000811 |
negative regulation of anoikis
|
BCL2, PIK3CA, SRC |
2.30228 |
|
[BP] GO:0032075 |
None
|
HSPA1A, PRKCD, PTPN1 |
2.30228 |
|
[BP] GO:0030540 |
female genitalia development
|
AXL, CYP19A1, ESR1 |
2.30228 |
|
[BP] GO:0070920 |
None
|
EGFR, ESR1, TERT |
2.30228 |
|
[BP] GO:0032225 |
None
|
DRD1, DRD2, PTGS2 |
2.30228 |
|
[BP] GO:0019372 |
lipoxygenase pathway
|
ALOX15, ALOX5, PTGS2 |
2.30228 |
|
[BP] GO:0040008 |
regulation of growth
|
APP, AR, BCL2, CSNK2A1, DRD2, EGFR, ESR2, HSPA1A, INSR, PIK3CA, PIM1, PTPRS, SMAD3, TNKS2 |
2.29748 |
|
[BP] GO:0010959 |
None
|
ADORA1, BCL2, DRD1, DRD2, GPR35, HTR2A, OPRD1, OPRK1, PRKCE, PTGS2 |
2.27965 |
|
[BP] GO:0022602 |
ovulation cycle process
|
BCL2, ESR1, KIT, PGR, SRC |
2.27437 |
|
[BP] GO:0022898 |
None
|
ABCB1, APP, BCL2, DRD2, GPR35, MMP9, OPRM1, PRKCE |
2.26346 |
|
[BP] GO:0019538 |
protein metabolic process
|
ACHE, ALPL, APP, AR, AURKB, AXL, BACE1, BCL2, CDC25B, CSNK2A1, DRD1, DUSP3, DYRK1A, EGFR, ESR1, F10, F3, FLT3, FUT7, HTR2B, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIM1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, PTPRS, SENP6, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
2.25782 |
|
[BP] GO:0042060 |
None
|
ALOX15, EGFR, OPRM1, PPARA, SMAD3 |
2.25054 |
|
[BP] GO:0010675 |
None
|
ESRRB, INSR, PPARA, PRKCE, RORC, SRC |
2.24937 |
|
[BP] GO:0045776 |
None
|
ADORA1, CNR1, DRD2, PPARA |
2.23893 |
|
[BP] GO:0050731 |
positive regulation of peptidyl-tyrosine phosphorylation
|
ADORA1, FLT3, HTR2A, KIT, MIF, PTPN1, SRC |
2.23671 |
|
[BP] GO:0043467 |
regulation of generation of precursor metabolites and energy
|
ESRRB, HTR2A, INSR, OPRK1, PIK3CA, PPARA |
2.23166 |
|
[BP] GO:0008631 |
intrinsic apoptotic signaling pathway in response to oxidative stress
|
BCL2, CYP1B1, PRKCD |
2.22955 |
|
[BP] GO:1904355 |
positive regulation of telomere capping
|
AURKB, TNKS, TNKS2 |
2.22955 |
|
[BP] GO:0009214 |
None
|
PDE10A, PDE3A, PDE3B |
2.22955 |
|
[BP] GO:0006807 |
nitrogen compound metabolic process
|
ACHE, AKR1B1, AKR1B10, AKR1C3, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BACE1, BCL2, CDC25B, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, CYP3A4, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FLT3, FUT7, GLO1, HSPA1A, HTR1A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP12, MMP2, MMP9, NR3C1, NR3C2, NUAK1, PDE10A, PDE3A, PDE3B, PGR, PIK3CA, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS2, PTPN1, PTPRS, RORC, SENP6, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
2.2272 |
|
[BP] GO:0006109 |
regulation of carbohydrate metabolic process
|
ESRRB, HTR2A, INSR, PPARA, PRKCE, RORC, SRC |
2.22542 |
|
[BP] GO:0006195 |
None
|
PDE10A, PDE3A, PDE3B, XDH |
2.20524 |
|
[BP] GO:0043551 |
regulation of phosphatidylinositol 3-kinase activity
|
FLT3, KIT, SRC, TEK |
2.20524 |
|
[BP] GO:0032355 |
response to estradiol
|
CYP1A2, EGFR, ESR1, ESRRA, HTR5A, PTGS2 |
2.19907 |
|
[BP] GO:0045765 |
regulation of angiogenesis
|
CYP1B1, F3, KDR, PDE3B, PRKCA, PRKCB, PTGS2, TEK, TERT |
2.19863 |
|
[BP] GO:0019932 |
second-messenger-mediated signaling
|
DRD1, DRD2, EGFR, HTR2B, HTR5A, KDR, OPRM1, PDE3A |
2.18582 |
|
[BP] GO:0070542 |
None
|
AKR1C3, FABP3, PRKCE, PTGS2, SRC |
2.18409 |
|
[BP] GO:0045833 |
None
|
ADORA1, AKR1C3, CNR1, HCAR2, PDE3B |
2.18409 |
|
[BP] GO:1901570 |
None
|
ALOX15, ALOX5, MIF, PTGS1, PTGS2 |
2.18409 |
|
[BP] GO:0034762 |
None
|
ABCB1, APP, BCL2, CA2, DRD1, DRD2, GPR35, MMP9, OPRK1, OPRM1, PRKCE |
2.1779 |
|
[BP] GO:0030818 |
None
|
DRD2, HTR1B, OPRM1, PRKCA |
2.17132 |
|
[BP] GO:0010557 |
positive regulation of macromolecule biosynthetic process
|
APP, AR, AURKB, DRD2, EGFR, ESR1, ESR2, ESRRA, ESRRB, IGF1R, INSR, KDR, MET, MMP12, NR3C1, PGR, PPARA, RORC, SMAD3, SOAT1, SRC, TERT, TNKS, TNKS2, TOP2A |
2.16404 |
|
[BP] GO:0072488 |
None
|
SLC22A1, SLC22A2, SLC22A3 |
2.16404 |
|
[BP] GO:0016137 |
None
|
AKR1B1, AKR1B10, AKR1C3 |
2.16404 |
|
[BP] GO:0032095 |
None
|
OPRM1, PPARA, PRKCG |
2.16404 |
|
[BP] GO:0045821 |
None
|
ESRRB, HTR2A, INSR |
2.16404 |
|
[BP] GO:0071453 |
cellular response to oxygen levels
|
BCL2, OPRD1, PRKCE, PTGS2, SRC, TERT |
2.15136 |
|
[BP] GO:2000106 |
regulation of leukocyte apoptotic process
|
AURKB, AXL, HCAR2, MIF, PIK3CB |
2.14068 |
|
[BP] GO:0033273 |
response to vitamin
|
ALPL, CYP1A1, EGFR, PTGS2, TYR |
2.14068 |
|
[BP] GO:1903426 |
None
|
EGFR, INSR, PTGS2, SMAD3, TRPV1 |
2.14068 |
|
[BP] GO:0009896 |
positive regulation of catabolic process
|
CSNK2A1, ESRRB, HSPA1A, HTR2A, INSR, KDR, PIK3CB, PPARA, PRKCD, PRKCE, PTPN1 |
2.13466 |
|
[BP] GO:0006816 |
None
|
DRD2, HTR2A, HTR2B, HTR2C, OPRM1, PRKCB, PRKCE, TRPV1 |
2.12204 |
|
[BP] GO:0015850 |
None
|
DRD1, SLC22A1, SLC22A2, SLC22A3, SOAT1, SOAT2 |
2.11944 |
|
[BP] GO:0001816 |
cytokine production
|
APP, FABP4, KIT, PRKCD, PTGS2 |
2.11944 |
|
[BP] GO:0009605 |
response to external stimulus
|
ADORA1, AKR1C3, ALPL, AXL, BCL2, CNR1, CNR2, CYP1A1, CYP1A2, EGFR, HSD11B2, HTR2A, KIT, MMP12, OPRK1, OPRM1, PRKCD, PTGS2, SMAD3, SRC, TRPV1, TYR |
2.11614 |
|
[BP] GO:1901374 |
None
|
SLC22A1, SLC22A2 |
2.11284 |
|
[BP] GO:0033031 |
positive regulation of neutrophil apoptotic process
|
HCAR2, PIK3CB |
2.11284 |
|
[BP] GO:0070213 |
None
|
TNKS, TNKS2 |
2.11284 |
|
[BP] GO:0006145 |
None
|
AOX1, XDH |
2.11284 |
|
[BP] GO:0038171 |
None
|
CNR1, CNR2 |
2.11284 |
|
[BP] GO:0015874 |
None
|
SLC22A1, SLC22A2 |
2.11284 |
|
[BP] GO:0018894 |
dibenzo-p-dioxin metabolic process
|
CYP1A1, CYP1A2 |
2.11284 |
|
[BP] GO:0014827 |
None
|
HTR1D, HTR2B |
2.11284 |
|
[BP] GO:0030803 |
None
|
DRD2, HTR1B, OPRM1, PRKCA |
2.1128 |
|
[BP] GO:0051091 |
positive regulation of DNA binding transcription factor activity
|
APP, AR, ESR1, ESR2, HSPA1A, KIT, OPRD1, PRKCB |
2.10786 |
|
[BP] GO:0016048 |
None
|
ADORA1, HTR2A, TRPV1 |
2.10771 |
|
[BP] GO:0051900 |
regulation of mitochondrial depolarization
|
BCL2, KDR, SRC |
2.10771 |
|
[BP] GO:0051197 |
None
|
ESRRB, HTR2A, INSR |
2.10771 |
|
[BP] GO:0051781 |
None
|
AURKB, CDC25B, DRD2, HTR2B, PRKCE |
2.10676 |
|
[BP] GO:1901989 |
None
|
APEX1, APP, CDC25B, CYP1A1, TERT |
2.10676 |
|
[BP] GO:0060191 |
regulation of lipase activity
|
EGFR, ESR1, HTR2A, HTR2B, KIT |
2.0839 |
|
[BP] GO:0010595 |
positive regulation of endothelial cell migration
|
KDR, MET, PRKCA, PTGS2, TEK |
2.0839 |
|
[BP] GO:0048638 |
regulation of developmental growth
|
APP, AR, BCL2, DRD2, INSR, PIK3CA, PIM1, PTPRS, TNKS2 |
2.078 |
|
[BP] GO:1901361 |
None
|
AOX1, CYP19A1, CYP1A1, CYP1A2, CYP2A6, CYP3A4, HSPA1A, PDE10A, PDE3A, PDE3B, XDH |
2.07728 |
|
[BP] GO:0070588 |
None
|
DRD2, HTR2A, HTR2B, HTR2C, OPRM1, PRKCE, TRPV1 |
2.06543 |
|
[BP] GO:0001936 |
None
|
F3, HTR2B, KDR, PRKCA, TEK, XDH |
2.06451 |
|
[BP] GO:0044259 |
multicellular organismal macromolecule metabolic process
|
AKR1C3, MMP1, MMP12, MMP2, MMP9 |
2.06451 |
|
[BP] GO:0001938 |
None
|
F3, HTR2B, KDR, PRKCA, TEK |
2.06451 |
|
[BP] GO:0008542 |
None
|
APP, DRD1, DRD2, KIT |
2.05077 |
|
[BP] GO:2000026 |
regulation of multicellular organismal development
|
APP, AR, AXL, BCL2, CA2, CNR1, CYP1B1, DRD2, EGFR, ESR1, ESRRA, F3, INSR, KDR, KIT, OPRM1, PDE3B, PIM1, PRKCA, PRKCB, PTGS2, PTPRS, SMAD3, SRC, TEK, TERT, XDH |
2.04864 |
|
[BP] GO:0051341 |
None
|
CNR1, CNR2, EGFR, HTR2B, TERT |
2.02145 |
|
[BP] GO:1900372 |
None
|
DRD2, HTR1B, OPRM1, PRKCA |
2.0209 |
|
[BP] GO:2000351 |
None
|
AKR1C3, KDR, TEK, TERT |
2.0209 |
|
[BP] GO:0030809 |
None
|
DRD2, HTR1B, OPRM1, PRKCA |
2.0209 |
|
[BP] GO:0046626 |
regulation of insulin receptor signaling pathway
|
PRKCB, PRKCD, PTPN1, SRC |
2.0209 |
|
[BP] GO:0008285 |
negative regulation of cell proliferation
|
ADORA1, ADORA3, APP, AR, BCL2, CYP1B1, DRD2, FABP3, HSPA1A, OPRM1, PTGS2, SMAD3, TERT, XDH |
2.02049 |
|
[BP] GO:0007623 |
circadian rhythm
|
DRD2, DYRK1A, EGFR, HTR7, PPARA, RORC |
2.01978 |
|
[CC] GO:0031226 |
intrinsic component of plasma membrane
|
ADORA1, ADORA3, APP, AXL, BACE1, CA4, CNR1, CNR2, DRD1, DRD2, F10, F3, FLT3, GPR35, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, OPRD1, OPRK1, OPRM1, PTPRS, SIGMAR1, SLC22A1, SLC22A2, SLC22A3, TEK, TRPV1 |
10.5091 |
|
[CC] GO:0005886 |
plasma membrane
|
ABCB1, ACHE, ADORA1, ADORA3, ALOX15, ALPL, APP, AR, AXL, BACE1, CA12, CA14, CA2, CA4, CA9, CNR1, CNR2, CSNK2A1, DRD1, DRD2, EGFR, ESR1, F10, F3, FLT3, GLO1, GPR35, HCAR2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MET, MMP2, OPRD1, OPRK1, OPRM1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, PTPRS, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SMAD3, SRC, TEK, TERT, TRPV1 |
9.62022 |
|
[CC] GO:0016020 |
membrane
|
ABCB1, ACHE, ADORA1, ADORA3, ALOX15, ALOX5, ALPL, APP, AR, AXL, BACE1, BCL2, CA12, CA14, CA2, CA4, CA9, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DRD1, DRD2, EGFR, ESR1, F10, F3, FLT3, FUT7, GLO1, GPR35, HCAR2, HSD11B1, HSD11B2, HSD17B2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MET, MMP2, NR3C2, OPRD1, OPRK1, OPRM1, PDE10A, PDE3B, PGR, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, PTPRS, SIGMAR1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SMAD3, SOAT1, SOAT2, SRC, TEK, TERT, TNKS, TNKS2, TRPV1, TYR |
9.40238 |
|
[CC] GO:0005887 |
integral component of plasma membrane
|
ADORA1, ADORA3, APP, AXL, BACE1, CNR1, CNR2, DRD1, DRD2, FLT3, GPR35, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, OPRD1, OPRK1, OPRM1, PTPRS, SIGMAR1, SLC22A1, SLC22A2, SLC22A3, TEK, TRPV1 |
9.1804 |
|
[CC] GO:0044459 |
plasma membrane part
|
ABCB1, ADORA1, ADORA3, ALOX15, APP, AXL, BACE1, CA2, CA4, CA9, CNR1, CNR2, DRD1, DRD2, DUSP3, EGFR, F10, F3, FLT3, GPR35, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MET, OPRD1, OPRK1, OPRM1, PRKCG, PTGS2, PTPRS, SIGMAR1, SLC22A1, SLC22A2, SLC22A3, SRC, TEK, TRPV1 |
8.34446 |
|
[CC] GO:0044425 |
membrane part
|
ABCB1, ACHE, ADORA1, ADORA3, ALOX15, ALPL, APP, AXL, BACE1, BCL2, CA12, CA14, CA2, CA4, CA9, CNR1, CNR2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DRD1, DRD2, DUSP3, EGFR, ESR1, F10, F3, FLT3, FUT7, GPR35, HCAR2, HSD11B1, HSD11B2, HSD17B2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MET, NR3C2, OPRD1, OPRK1, OPRM1, PDE3A, PDE3B, PIK3CA, PIK3CB, PRKCG, PTGS1, PTGS2, PTPN1, PTPRS, SIGMAR1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SOAT1, SOAT2, SRC, TEK, TRPV1, TYR |
6.64203 |
|
[CC] GO:0005783 |
None
|
ADORA1, APEX1, APP, BCL2, CA4, CYP19A1, CYP2D6, FLT3, HSPA1A, HTR5A, KDR, OPRM1, PDE3B, PRKCA, PRKCD, PRKCE, PTGS2, PTPN1, SIGMAR1, SOAT1, SOAT2, XDH |
4.47735 |
|
[CC] GO:0045121 |
membrane raft
|
APP, BACE1, CNR1, EGFR, HTR2A, INSR, KDR, OPRD1, OPRM1, PTGS2, SRC, TEK |
4.23865 |
|
[CC] GO:0044464 |
cell part
|
ABCB1, ACHE, ADORA1, ADORA3, AKR1B1, AKR1B10, AKR1C3, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA7, CA9, CBR1, CDC25B, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, FUT7, GLO1, GPR35, HCAR2, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MET, MIF, MMP12, MMP2, MMP9, NQO2, NR3C1, NR3C2, NUAK1, OPRD1, OPRK1, OPRM1, PDE10A, PDE3A, PDE3B, PGR, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SENP6, SIGMAR1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SMAD3, SOAT1, SOAT2, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, TUBB3, TYR, XDH |
4.22777 |
|
[CC] GO:0098857 |
membrane microdomain
|
APP, BACE1, CNR1, EGFR, HTR2A, INSR, KDR, OPRD1, OPRM1, PTGS2, SRC, TEK |
4.214 |
|
[CC] GO:0044444 |
cytoplasmic part
|
ACHE, ADORA1, AKR1B1, AKR1B10, AKR1C3, ALOX15, ALOX5, AOX1, APEX1, APP, AR, AURKB, BACE1, BCL2, CA1, CA2, CA4, CA5A, CA5B, CA7, CBR1, CDC25B, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DRD1, DRD2, DUSP3, EGFR, ESR1, ESR2, F10, FABP3, FABP4, FLT3, FUT7, GLO1, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR2A, HTR4, HTR5A, INSR, KDR, KIT, MIF, MMP2, MMP9, NQO2, NR3C1, NR3C2, OPRM1, PDE10A, PDE3A, PDE3B, PGR, PIK3CA, PIK3CB, PIM1, POLA1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, PTPRS, SENP6, SIGMAR1, SMAD3, SOAT1, SOAT2, SRC, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
3.93238 |
|
[CC] GO:0044432 |
endoplasmic reticulum part
|
APP, BACE1, BCL2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DRD1, EGFR, F10, FLT3, HSD11B1, HSD11B2, HSD17B2, NR3C2, PTGS1, PTGS2, PTPN1, SIGMAR1, SOAT1, SOAT2 |
3.88809 |
|
[CC] GO:0098590 |
plasma membrane region
|
ABCB1, ADORA1, CA2, CA4, CA9, CNR1, DRD1, DRD2, EGFR, HTR2A, INSR, MET, OPRD1, OPRM1, PRKCG, PTGS2, SIGMAR1, SLC22A1, SRC, TEK, TRPV1 |
3.7292 |
|
[CC] GO:0005789 |
endoplasmic reticulum membrane
|
BCL2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DRD1, EGFR, HSD11B1, HSD11B2, HSD17B2, NR3C2, PTGS1, PTGS2, SIGMAR1, SOAT1, SOAT2 |
3.58843 |
|
[CC] GO:0098589 |
membrane region
|
APP, BACE1, CNR1, EGFR, HTR2A, INSR, KDR, OPRD1, OPRM1, PTGS2, SRC, TEK |
3.50008 |
|
[CC] GO:0031224 |
None
|
ABCB1, ACHE, ADORA1, ADORA3, ALPL, APP, AXL, BACE1, CA12, CA14, CA4, CA9, CNR1, CNR2, CYP3A4, DRD1, DRD2, EGFR, ESR1, F10, F3, FLT3, FUT7, GPR35, HCAR2, HSD11B1, HSD17B2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MET, OPRD1, OPRK1, OPRM1, PDE3A, PDE3B, PTPRS, SIGMAR1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SOAT1, SOAT2, TEK, TRPV1, TYR |
3.43181 |
|
[CC] GO:0032589 |
None
|
ADORA1, INSR, OPRD1, OPRM1, TRPV1 |
3.3694 |
|
[CC] GO:0043005 |
None
|
ADORA1, APP, BACE1, CA2, CNR1, CNR2, DRD2, HTR2A, HTR2B, HTR5A, OPRD1, OPRK1, OPRM1, PRKCG, PTGS2, PTPRS, SRC, TUBB3 |
3.3694 |
|
[CC] GO:0043204 |
None
|
CNR2, DRD2, HTR5A, OPRK1, OPRM1, PDE10A, PTPRS |
3.17859 |
|
[CC] GO:0043227 |
membrane-bounded organelle
|
ABCB1, ACHE, ADORA1, AKR1B1, AKR1B10, AKR1C3, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BACE1, BCL2, CA1, CA2, CA4, CA5A, CA5B, CA6, CBR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, CYP3A4, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, FUT7, GLO1, HSPA1A, HTR2A, HTR4, HTR5A, IGF1R, INSR, KDR, KIT, MIF, MMP12, MMP2, MMP9, NQO2, NR3C1, NUAK1, OPRD1, OPRM1, PDE3B, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SIGMAR1, SLC22A2, SLC47A1, SMAD3, SOAT1, SOAT2, SRC, TERT, TNKS, TNKS2, TOP2A, TUBB3, TYR, XDH |
2.96874 |
|
[CC] GO:0097458 |
None
|
ADORA1, APP, BACE1, CA2, CNR1, CNR2, DRD2, HTR2A, HTR2B, HTR5A, INSR, OPRD1, OPRK1, OPRM1, PDE10A, PRKCG, PTGS1, PTGS2, PTPRS, SIGMAR1, SLC22A2, SRC, TRPV1, TUBB3 |
2.93036 |
|
[CC] GO:0120025 |
None
|
ADORA1, AKR1B1, APP, BACE1, CA2, CNR1, CNR2, DRD1, DRD2, HTR2A, HTR2B, HTR5A, HTR6, OPRD1, OPRK1, OPRM1, PIK3CA, PRKCG, PTGS2, PTPRS, SRC, TEK, TUBB3 |
2.9206 |
|
[CC] GO:0016021 |
None
|
ABCB1, ADORA1, ADORA3, ALPL, APP, AXL, BACE1, CA12, CA14, CA9, CNR1, CNR2, CYP3A4, DRD1, DRD2, EGFR, ESR1, F3, FLT3, FUT7, GPR35, HCAR2, HSD11B1, HSD17B2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MET, OPRD1, OPRK1, OPRM1, PDE3A, PDE3B, PTPRS, SIGMAR1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SOAT1, SOAT2, TEK, TRPV1, TYR |
2.81319 |
|
[CC] GO:0031253 |
None
|
ADORA1, CA4, CA9, DRD1, DRD2, INSR, OPRD1, OPRM1, SRC, TRPV1 |
2.63194 |
|
[CC] GO:0042995 |
cell projection
|
ADORA1, AKR1B1, APP, BACE1, CA2, CNR1, CNR2, DRD1, DRD2, HTR2A, HTR2B, HTR5A, HTR6, OPRD1, OPRK1, OPRM1, PIK3CA, PRKCG, PTGS2, PTPRS, SRC, TEK, TUBB3 |
2.61583 |
|
[CC] GO:0030424 |
None
|
APP, BACE1, CA2, CNR1, DRD2, HTR2A, OPRM1, PTPRS, TUBB3 |
2.60039 |
|
[CC] GO:0032590 |
None
|
INSR, OPRD1, OPRM1 |
2.4465 |
|
[CC] GO:0048471 |
perinuclear region of cytoplasm
|
ACHE, AKR1B1, APEX1, APP, CA4, EGFR, HSPA1A, PRKCA, PRKCD, PRKCE, PRKCG, SRC, TNKS2, TYR |
2.33747 |
|
[CC] GO:0043226 |
organelle
|
ABCB1, ACHE, ADORA1, AKR1B1, AKR1B10, AKR1C3, ALOX15, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BACE1, BCL2, CA1, CA2, CA4, CA5A, CA5B, CA6, CA9, CBR1, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, CYP3A4, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, FUT7, GLO1, HSPA1A, HTR2A, HTR4, HTR5A, HTR6, IGF1R, INSR, KDR, KIT, MIF, MMP12, MMP2, MMP9, NQO2, NR3C1, NUAK1, OPRD1, OPRM1, PDE3B, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SIGMAR1, SLC22A2, SLC47A1, SMAD3, SOAT1, SOAT2, SRC, TERT, TNKS, TNKS2, TOP2A, TUBB3, TYR, XDH |
2.22409 |
|
[CC] GO:0031982 |
None
|
ABCB1, AKR1B1, AKR1B10, AKR1C3, ALPL, AOX1, APP, AXL, BACE1, CA1, CA2, CA4, CA6, CBR1, DRD2, DUSP3, EGFR, F3, FABP3, FABP4, GLO1, HSPA1A, HTR2A, HTR4, INSR, KDR, KIT, MIF, MMP9, NQO2, OPRD1, OPRM1, PRKCA, PRKCB, PRKCD, PTGS1, PTPN1, PTPRS, SIGMAR1, SLC22A2, SLC47A1, SRC, TUBB3, TYR |
2.16909 |
|
[CC] GO:0016323 |
basolateral plasma membrane
|
ADORA1, CA2, CA4, CA9, EGFR, SLC22A1, TEK |
2.078 |
|
[CC] GO:0044456 |
None
|
ACHE, ADORA1, APP, CNR1, DRD2, OPRD1, OPRK1, OPRM1, PRKCG, PTPRS, SIGMAR1, SLC22A2, SRC, TRPV1 |
2.06451 |
|
[CC] GO:0031233 |
None
|
CA4, F10, F3 |
2.04796 |
|
[MF] GO:0043167 |
ion binding
|
ABCB1, ACHE, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DNMT1, DRD1, DRD2, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, GLO1, HSD17B1, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NR3C2, NUAK1, PDE10A, PDE3A, PDE3B, PGR, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SMAD3, SOAT1, SOAT2, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, TUBB3, TYR, XDH |
21.7289 |
|
[MF] GO:0046914 |
transition metal ion binding
|
ALOX15, ALOX5, AOX1, APP, AR, CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DNMT1, ESR1, ESR2, ESRRA, ESRRB, GLO1, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NR3C2, PGR, PIM1, PPARA, PRKCA, PRKCB, PRKCG, PTPN1, RORC, SMAD3, TNKS, TYR, XDH |
21.2203 |
|
[MF] GO:0043169 |
cation binding
|
ACHE, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DNMT1, DRD1, DRD2, ESR1, ESR2, ESRRA, ESRRB, F10, GLO1, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7, KIT, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NR3C2, NUAK1, PDE10A, PDE3A, PDE3B, PGR, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SMAD3, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
16.7325 |
|
[MF] GO:0004089 |
carbonate dehydratase activity
|
CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9 |
15.0087 |
|
[MF] GO:0038023 |
signaling receptor activity
|
ADORA1, ADORA3, AR, AXL, CNR1, CNR2, DRD1, DRD2, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, HCAR2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MET, NR3C1, NR3C2, OPRD1, OPRK1, OPRM1, PGR, PPARA, RORC, SIGMAR1, TEK, TRPV1 |
14.7015 |
|
[MF] GO:0043176 |
None
|
HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7 |
14.6807 |
|
[MF] GO:0051378 |
None
|
HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7 |
14.6807 |
|
[MF] GO:0003824 |
catalytic activity
|
ABCB1, ACHE, ADORA1, AKR1B1, AKR1B10, AKR1C3, ALOX15, ALOX5, ALPL, AOX1, APEX1, AURKB, AXL, BACE1, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CBR1, CDC25B, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DNMT1, DUSP3, DYRK1A, EGFR, F10, F3, FLT3, FUT7, GLO1, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, IGF1R, INSR, KDR, KIT, MET, MIF, MMP1, MMP12, MMP2, MMP9, NQO2, NUAK1, PDE10A, PDE3A, PDE3B, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, PTPRS, SENP6, SOAT1, SOAT2, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TUBB3, TYR, XDH |
14.5646 |
|
[MF] GO:0004993 |
None
|
HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7 |
14.5646 |
|
[MF] GO:0099589 |
None
|
HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7 |
14.5646 |
|
[MF] GO:0099528 |
None
|
HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, OPRM1 |
13.8221 |
|
[MF] GO:0004872 |
receptor activity
|
ADORA1, ADORA3, AR, AXL, CNR1, CNR2, DRD1, DRD2, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, HCAR2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MET, NR3C1, NR3C2, OPRD1, OPRK1, OPRM1, PGR, PPARA, RORC, SIGMAR1, TEK, TRPV1 |
13.0823 |
|
[MF] GO:0004871 |
signal transducer activity
|
ADORA1, ADORA3, AR, AXL, CNR1, CNR2, DRD1, DRD2, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, HCAR2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MET, NR3C1, NR3C2, OPRD1, OPRK1, OPRM1, PGR, PPARA, PRKCE, RORC, SIGMAR1, SMAD3, TEK, TRPV1 |
13.0099 |
|
[MF] GO:0060089 |
molecular transducer activity
|
ADORA1, ADORA3, AR, AXL, CNR1, CNR2, DRD1, DRD2, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, HCAR2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MET, NR3C1, NR3C2, OPRD1, OPRK1, OPRM1, PGR, PPARA, RORC, SIGMAR1, TEK, TRPV1 |
12.6166 |
|
[MF] GO:0008270 |
zinc ion binding
|
AR, CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, DNMT1, ESR1, ESR2, ESRRA, ESRRB, GLO1, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NR3C2, PGR, PPARA, PRKCA, PRKCB, PRKCG, PTPN1, RORC, SMAD3, TNKS |
12.4576 |
|
[MF] GO:0005496 |
steroid binding
|
AR, CYP3A4, ESR1, ESR2, ESRRA, ESRRB, HSD11B2, HSD17B1, NR3C1, NR3C2, PGR, RORC, SOAT1, SOAT2 |
12.3158 |
|
[MF] GO:0008144 |
drug binding
|
ABCB1, ACHE, AURKB, AXL, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2D6, CYP3A4, DRD1, DRD2, DYRK1A, EGFR, FLT3, HSPA1A, HTR1B, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, KIT, MET, NQO2, NUAK1, PDE10A, PIK3CA, PIK3CB, PIM1, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SIGMAR1, SRC, TEK, TOP2A, TRPV1 |
12.2134 |
|
[MF] GO:0008227 |
None
|
DRD2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7 |
11.704 |
|
[MF] GO:0030594 |
None
|
DRD1, DRD2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, OPRM1 |
10.969 |
|
[MF] GO:0070405 |
ammonium ion binding
|
ACHE, DRD1, DRD2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7 |
10.5091 |
|
[MF] GO:0016835 |
carbon-oxygen lyase activity
|
APEX1, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, POLB |
10.3887 |
|
[MF] GO:0046872 |
metal ion binding
|
ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DNMT1, ESR1, ESR2, ESRRA, ESRRB, F10, GLO1, KIT, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NR3C2, NUAK1, PDE10A, PDE3A, PDE3B, PGR, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SMAD3, TERT, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
10.373 |
|
[MF] GO:0042165 |
neurotransmitter binding
|
ACHE, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7 |
9.30748 |
|
[MF] GO:0099600 |
transmembrane receptor activity
|
ADORA1, ADORA3, AXL, CNR1, CNR2, DRD1, DRD2, EGFR, F3, FLT3, GPR35, HCAR2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MET, OPRD1, OPRK1, OPRM1, SIGMAR1, TEK, TRPV1 |
9.20423 |
|
[MF] GO:0004888 |
transmembrane signaling receptor activity
|
ADORA1, ADORA3, AXL, CNR1, CNR2, DRD1, DRD2, EGFR, F3, FLT3, GPR35, HCAR2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MET, OPRD1, OPRK1, OPRM1, SIGMAR1, TEK, TRPV1 |
9.20423 |
|
[MF] GO:0016836 |
hydro-lyase activity
|
CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9 |
9.08827 |
|
[MF] GO:0016712 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4 |
8.92367 |
|
[MF] GO:0003707 |
steroid hormone receptor activity
|
AR, ESR1, ESR2, ESRRA, ESRRB, NR3C1, NR3C2, PGR, PPARA, RORC |
8.80303 |
|
[MF] GO:0016491 |
oxidoreductase activity
|
AKR1B1, AKR1B10, AKR1C3, ALOX15, ALOX5, AOX1, APEX1, CBR1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, HSD11B1, HSD11B2, HSD17B1, HSD17B2, NQO2, PTGS1, PTGS2, TYR, XDH |
8.30791 |
|
[MF] GO:0070330 |
aromatase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2D6, CYP3A4 |
7.65909 |
|
[MF] GO:0097159 |
organic cyclic compound binding
|
ABCB1, ADORA1, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DNMT1, DRD1, DRD2, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, FLT3, HSD11B2, HSD17B1, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7, IGF1R, INSR, KDR, KIT, MET, MMP12, NQO2, NR3C1, NR3C2, NUAK1, PDE10A, PDE3A, PGR, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SOAT1, SOAT2, SRC, TEK, TERT, TOP2A, TRPV1, TUBB3, XDH |
7.49605 |
|
[MF] GO:0004714 |
transmembrane receptor protein tyrosine kinase activity
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, KIT, MET, TEK |
7.25927 |
|
[MF] GO:0016829 |
lyase activity
|
APEX1, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, GLO1, POLB |
7.19675 |
|
[MF] GO:0016705 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
|
AKR1C3, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, PTGS1, PTGS2, TYR |
6.98891 |
|
[MF] GO:0048037 |
cofactor binding
|
AOX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, HSD11B2, HSD17B1, NQO2, POLA1, PTGS1, PTGS2, SOAT1, SOAT2, SRC, XDH |
6.93012 |
|
[MF] GO:0004497 |
monooxygenase activity
|
AKR1C3, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, TYR |
6.87258 |
|
[MF] GO:0005506 |
iron ion binding
|
ALOX15, ALOX5, AOX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, XDH |
6.85068 |
|
[MF] GO:0008289 |
lipid binding
|
ALOX15, AR, AXL, CYP3A4, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, HSD11B2, HSD17B1, NR3C1, NR3C2, PGR, PPARA, RORC, SOAT1, SOAT2, TRPV1 |
6.78998 |
|
[MF] GO:0020037 |
heme binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, PTGS1, PTGS2, SRC |
6.78998 |
|
[MF] GO:0098531 |
transcription factor activity, direct ligand regulated sequence-specific DNA binding
|
AR, ESR1, ESR2, ESRRA, ESRRB, PGR, PPARA, RORC |
6.75737 |
|
[MF] GO:0004879 |
nuclear receptor activity
|
AR, ESR1, ESR2, ESRRA, ESRRB, PGR, PPARA, RORC |
6.75737 |
|
[MF] GO:0046906 |
tetrapyrrole binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, PTGS1, PTGS2, SRC |
6.48099 |
|
[MF] GO:0019199 |
transmembrane receptor protein kinase activity
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, KIT, MET, TEK |
6.39711 |
|
[MF] GO:0004672 |
protein kinase activity
|
AURKB, AXL, CSNK2A1, DYRK1A, EGFR, FLT3, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK |
6.35102 |
|
[MF] GO:0004713 |
protein tyrosine kinase activity
|
AXL, DYRK1A, EGFR, FLT3, IGF1R, INSR, KDR, KIT, MET, PRKCD, SRC, TEK |
6.30689 |
|
[MF] GO:0043560 |
insulin receptor substrate binding
|
IGF1R, INSR, PIK3CA, PIK3CB, PRKCD |
6.17302 |
|
[MF] GO:1901363 |
heterocyclic compound binding
|
ABCB1, ADORA1, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DNMT1, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, FLT3, HSD11B2, HSD17B1, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR7, IGF1R, INSR, KDR, KIT, MET, MMP12, NQO2, NR3C1, NR3C2, NUAK1, PDE10A, PDE3A, PGR, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, RORC, SMAD3, SRC, TEK, TERT, TOP2A, TRPV1, TUBB3, XDH |
6.07214 |
|
[MF] GO:0016773 |
phosphotransferase activity, alcohol group as acceptor
|
AURKB, AXL, CSNK2A1, DYRK1A, EGFR, FLT3, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK |
5.72061 |
|
[MF] GO:0019825 |
oxygen binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2D6, CYP3A4 |
5.66879 |
|
[MF] GO:0016772 |
transferase activity, transferring phosphorus-containing groups
|
AURKB, AXL, CSNK2A1, DYRK1A, EGFR, FLT3, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TERT |
5.65741 |
|
[MF] GO:0004930 |
None
|
ADORA1, ADORA3, CNR1, CNR2, DRD1, DRD2, GPR35, HCAR2, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, OPRD1, OPRK1, OPRM1, SIGMAR1 |
5.59017 |
|
[MF] GO:0016614 |
oxidoreductase activity, acting on CH-OH group of donors
|
AKR1B1, AKR1B10, AKR1C3, AOX1, CBR1, HSD11B1, HSD11B2, HSD17B1, HSD17B2, XDH |
5.49999 |
|
[MF] GO:0036094 |
small molecule binding
|
ABCB1, ADORA1, AOX1, AURKB, AXL, CSNK2A1, DNMT1, DYRK1A, EGFR, FABP3, FABP4, FLT3, HSD11B2, HSD17B1, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NQO2, NUAK1, PDE10A, PDE3A, PIK3CA, PIK3CB, PIM1, POLA1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SOAT1, SOAT2, SRC, TEK, TOP2A, TRPV1, TUBB3, XDH |
5.4457 |
|
[MF] GO:0004697 |
None
|
PRKCA, PRKCB, PRKCD, PRKCE, PRKCG |
5.29958 |
|
[MF] GO:0016301 |
kinase activity
|
AURKB, AXL, CSNK2A1, DYRK1A, EGFR, FLT3, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK |
5.10601 |
|
[MF] GO:0008395 |
steroid hydroxylase activity
|
CYP19A1, CYP1A1, CYP2A13, CYP2A6, CYP2D6, CYP3A4 |
5.05512 |
|
[MF] GO:0042562 |
hormone binding
|
ACHE, AR, EGFR, HSD17B1, IGF1R, INSR, NQO2, NR3C1 |
4.99931 |
|
[MF] GO:0019899 |
enzyme binding
|
APP, AR, AURKB, BACE1, BCL2, CDC25B, CYP1A1, CYP1A2, CYP2A6, CYP3A4, DUSP3, EGFR, ESR1, ESR2, ESRRB, F3, HSPA1A, KIT, MET, MIF, NR3C1, PDE3B, PGR, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PTGS2, PTPN1, SMAD3, SRC, TEK, TNKS2, TOP2A |
4.96626 |
|
[MF] GO:0004985 |
None
|
OPRD1, OPRK1, OPRM1, SIGMAR1 |
4.93819 |
|
[MF] GO:0000166 |
nucleotide binding
|
ABCB1, AOX1, AURKB, AXL, CSNK2A1, DNMT1, DYRK1A, EGFR, FLT3, HSD11B2, HSD17B1, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NQO2, NUAK1, PDE10A, PDE3A, PIK3CA, PIK3CB, PIM1, POLA1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1, TUBB3, XDH |
4.91402 |
|
[MF] GO:1901265 |
nucleoside phosphate binding
|
ABCB1, AOX1, AURKB, AXL, CSNK2A1, DNMT1, DYRK1A, EGFR, FLT3, HSD11B2, HSD17B1, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NQO2, NUAK1, PDE10A, PDE3A, PIK3CA, PIK3CB, PIM1, POLA1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1, TUBB3, XDH |
4.91041 |
|
[MF] GO:0043168 |
anion binding
|
ABCB1, ALOX15, AOX1, APP, AURKB, AXL, CSNK2A1, DYRK1A, EGFR, F10, F3, FABP3, FABP4, FLT3, HSD17B1, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NQO2, NUAK1, PDE10A, PDE3A, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPRS, SOAT1, SOAT2, SRC, TEK, TOP2A, TRPV1, TUBB3, XDH |
4.75981 |
|
[MF] GO:0004716 |
signal transducer, downstream of receptor, with protein tyrosine kinase activity
|
EGFR, INSR, KDR, KIT |
4.71541 |
|
[MF] GO:0033764 |
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
|
AKR1C3, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
4.18629 |
|
[MF] GO:0032559 |
adenyl ribonucleotide binding
|
ABCB1, AURKB, AXL, CSNK2A1, DYRK1A, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NUAK1, PDE10A, PDE3A, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1 |
4.1356 |
|
[MF] GO:0004698 |
None
|
PRKCA, PRKCB, PRKCG |
4.10717 |
|
[MF] GO:0030554 |
adenyl nucleotide binding
|
ABCB1, AURKB, AXL, CSNK2A1, DYRK1A, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NUAK1, PDE10A, PDE3A, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1 |
4.08774 |
|
[MF] GO:0003674 |
molecular_function
|
ABCB1, ACHE, ADORA1, ADORA3, AKR1B1, AKR1B10, AKR1C3, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CBR1, CDC25B, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, FUT7, GLO1, GPR35, HCAR2, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR4, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MET, MIF, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NR3C2, NUAK1, OPRD1, OPRK1, OPRM1, PDE10A, PDE3A, PDE3B, PGR, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SENP6, SIGMAR1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2, SMAD3, SOAT1, SOAT2, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, TUBB3, TYR, XDH |
4.06329 |
|
[MF] GO:0016229 |
steroid dehydrogenase activity
|
AKR1C3, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
4.04448 |
|
[MF] GO:0016616 |
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
|
AKR1B1, AKR1B10, AKR1C3, CBR1, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
4.00383 |
|
[MF] GO:0005329 |
None
|
SLC22A1, SLC22A2, SLC22A3 |
3.50008 |
|
[MF] GO:0005524 |
ATP binding
|
ABCB1, AURKB, AXL, CSNK2A1, DYRK1A, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1 |
3.42638 |
|
[MF] GO:0097367 |
carbohydrate derivative binding
|
ABCB1, ADORA1, APP, AURKB, AXL, CSNK2A1, DYRK1A, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NUAK1, PDE10A, PDE3A, PIK3CA, PIK3CB, PIM1, POLA1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPRS, SRC, TEK, TOP2A, TRPV1, TUBB3 |
3.30568 |
|
[MF] GO:0016903 |
None
|
AKR1B1, AKR1B10, AKR1C3, AOX1, XDH |
3.23504 |
|
[MF] GO:0032555 |
purine ribonucleotide binding
|
ABCB1, AURKB, AXL, CSNK2A1, DYRK1A, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NUAK1, PDE10A, PDE3A, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1, TUBB3 |
3.032 |
|
[MF] GO:0042802 |
identical protein binding
|
ACHE, AOX1, APP, BCL2, CSNK2A1, DRD2, DYRK1A, EGFR, ESR1, ESR2, FLT3, IGF1R, KDR, KIT, MET, MIF, MMP9, NQO2, PGR, PTGS2, SLC22A1, SMAD3, TERT, TOP2A, TRPV1, TYR, XDH |
3.01642 |
|
[MF] GO:0017076 |
purine nucleotide binding
|
ABCB1, AURKB, AXL, CSNK2A1, DYRK1A, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NUAK1, PDE10A, PDE3A, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1, TUBB3 |
2.99263 |
|
[MF] GO:0032553 |
ribonucleotide binding
|
ABCB1, AURKB, AXL, CSNK2A1, DYRK1A, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NUAK1, PDE10A, PDE3A, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1, TUBB3 |
2.98248 |
|
[MF] GO:0008504 |
None
|
SLC22A1, SLC22A2, SLC22A3 |
2.96874 |
|
[MF] GO:0016725 |
oxidoreductase activity, acting on CH or CH2 groups
|
CYP1A2, CYP3A4, XDH |
2.96874 |
|
[MF] GO:0015651 |
None
|
SLC22A1, SLC22A2, SLC22A3 |
2.96874 |
|
[MF] GO:0004666 |
prostaglandin-endoperoxide synthase activity
|
PTGS1, PTGS2 |
2.75733 |
|
[MF] GO:0034736 |
None
|
SOAT1, SOAT2 |
2.75733 |
|
[MF] GO:0045550 |
None
|
AKR1B10, AKR1C3 |
2.75733 |
|
[MF] GO:0038052 |
RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
|
ESR1, ESR2 |
2.75733 |
|
[MF] GO:0004772 |
None
|
SOAT1, SOAT2 |
2.75733 |
|
[MF] GO:0003845 |
None
|
HSD11B1, HSD11B2 |
2.75733 |
|
[MF] GO:0004119 |
None
|
PDE3A, PDE3B |
2.75733 |
|
[MF] GO:0008389 |
None
|
CYP2A13, CYP2A6 |
2.75733 |
|
[MF] GO:0035403 |
None
|
PRKCA, PRKCB |
2.75733 |
|
[MF] GO:0071886 |
None
|
HTR2A, HTR2C |
2.75733 |
|
[MF] GO:0015238 |
None
|
ABCB1, SLC22A1, SLC22A2, SLC22A3, SLC47A1, SLC47A2 |
2.757 |
|
[MF] GO:0009931 |
None
|
PRKCA, PRKCB, PRKCG |
2.73263 |
|
[MF] GO:0140096 |
catalytic activity, acting on a protein
|
AURKB, AXL, BACE1, CDC25B, CSNK2A1, DUSP3, DYRK1A, EGFR, F10, F3, FLT3, IGF1R, INSR, KDR, KIT, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIK3CA, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTPN1, PTPRS, SENP6, SRC, TEK |
2.71904 |
|
[MF] GO:0010857 |
None
|
PRKCA, PRKCB, PRKCG |
2.63194 |
|
[MF] GO:0004674 |
protein serine/threonine kinase activity
|
AURKB, CSNK2A1, DYRK1A, EGFR, NUAK1, PIK3CA, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG |
2.61583 |
|
[MF] GO:0046934 |
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
|
EGFR, KIT, MET, PIK3CA, PIK3CB |
2.5171 |
|
[MF] GO:0009055 |
electron transfer activity
|
AKR1B1, AOX1, CYP19A1, CYP1A2, NQO2, XDH |
2.47354 |
|
[MF] GO:0047555 |
None
|
PDE10A, PDE3A, PDE3B |
2.4465 |
|
[MF] GO:0052813 |
phosphatidylinositol bisphosphate kinase activity
|
EGFR, KIT, MET, PIK3CA, PIK3CB |
2.43586 |
|
[MF] GO:0032403 |
protein complex binding
|
ACHE, ADORA1, APEX1, EGFR, ESRRB, FLT3, HTR2A, IGF1R, INSR, KDR, MMP12, MMP9, PPARA, PTPN1, SMAD3, SRC |
2.42511 |
|
[MF] GO:0035639 |
purine ribonucleoside triphosphate binding
|
ABCB1, AURKB, AXL, CSNK2A1, DYRK1A, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, KIT, MET, NUAK1, PIK3CA, PIK3CB, PIM1, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, SRC, TEK, TOP2A, TRPV1, TUBB3 |
2.40329 |
|
[MF] GO:0004115 |
None
|
PDE10A, PDE3A, PDE3B |
2.36676 |
|
[MF] GO:0050473 |
arachidonate 15-lipoxygenase activity
|
ALOX15, PTGS2 |
2.36676 |
|
[MF] GO:0015307 |
None
|
SLC47A1, SLC47A2 |
2.36676 |
|
[MF] GO:1901375 |
None
|
SLC22A1, SLC22A2 |
2.36676 |
|
[MF] GO:0047718 |
None
|
AKR1B10, AKR1C3 |
2.36676 |
|
[MF] GO:0070576 |
vitamin D 24-hydroxylase activity
|
CYP1A1, CYP3A4 |
2.36676 |
|
[MF] GO:0004949 |
None
|
CNR1, CNR2 |
2.36676 |
|
[MF] GO:0005333 |
None
|
SLC22A1, SLC22A2 |
2.36676 |
|
[MF] GO:0005277 |
None
|
SLC22A1, SLC22A2 |
2.36676 |
|
[MF] GO:0008513 |
None
|
SLC22A1, SLC22A2 |
2.36676 |
|
[MF] GO:0004699 |
None
|
PRKCD, PRKCE |
2.36676 |
|
[MF] GO:0044877 |
macromolecular complex binding
|
ACHE, ADORA1, APEX1, CSNK2A1, EGFR, ESRRB, FLT3, HTR2A, IGF1R, INSR, KDR, MMP12, MMP9, PIM1, PPARA, PTPN1, SMAD3, SRC |
2.33339 |
|
[MF] GO:0035004 |
phosphatidylinositol 3-kinase activity
|
EGFR, KIT, MET, PIK3CA, PIK3CB |
2.32135 |
|
[MF] GO:0019901 |
None
|
CDC25B, DUSP3, EGFR, ESR1, NR3C1, PDE3B, POLA1, PRKCB, PRKCD, PTPN1, SMAD3, SRC, TOP2A |
2.27066 |
|
[MF] GO:0019900 |
None
|
AURKB, CDC25B, DUSP3, EGFR, ESR1, NR3C1, PDE3B, POLA1, PRKCB, PRKCD, PTPN1, SMAD3, SRC, TOP2A |
2.25953 |
|
[MF] GO:0035173 |
histone kinase activity
|
AURKB, PRKCA, PRKCB |
2.22955 |
|
[MF] GO:0042578 |
None
|
ADORA1, ALPL, APEX1, CDC25B, DUSP3, PDE10A, PDE3A, PDE3B, PTPN1, PTPRS |
2.18592 |
|
[MF] GO:0033218 |
amide binding
|
ACHE, BACE1, IGF1R, INSR, NQO2, OPRD1, OPRK1, OPRM1, TUBB3 |
2.13466 |
|
[MF] GO:0005488 |
binding
|
ABCB1, ACHE, ADORA1, AKR1B10, ALOX15, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BACE1, BCL2, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CDC25B, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, CYP3A4, DNMT1, DRD1, DRD2, DUSP3, DYRK1A, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, GLO1, HSD11B2, HSD17B1, HSPA1A, HTR1A, HTR1B, HTR1D, HTR1E, HTR2A, HTR2B, HTR2C, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, KIT, MET, MIF, MMP1, MMP12, MMP2, MMP9, NQO2, NR3C1, NR3C2, NUAK1, OPRD1, OPRK1, OPRM1, PDE10A, PDE3A, PDE3B, PGR, PIK3CA, PIK3CB, PIM1, POLA1, POLB, PPARA, PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PTGS1, PTGS2, PTPN1, PTPRS, RORC, SENP6, SIGMAR1, SLC22A1, SLC22A3, SMAD3, SOAT1, SOAT2, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TRPV1, TUBB3, TYR, XDH |
2.11944 |
|
[MF] GO:0034056 |
estrogen response element binding
|
ESR1, ESR2 |
2.11284 |
|
[MF] GO:0034875 |
caffeine oxidase activity
|
CYP1A2, CYP3A4 |
2.11284 |
|
[MF] GO:0051425 |
None
|
APP, INSR |
2.11284 |
|
[MF] GO:0033695 |
oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor
|
CYP1A2, CYP3A4 |
2.11284 |
|
[MF] GO:0001965 |
None
|
HTR2A, HTR2B, OPRM1 |
2.10771 |
|
[MF] GO:0001223 |
transcription coactivator binding
|
ESR1, PPARA, TERT |
2.04796 |
|
[MF] GO:0035258 |
None
|
ESR1, FLT3, PRKCB, SMAD3, SRC |
2.02145 |
