| GO Term |
GO Name |
Enriched Genes |
Log10 Adjusted P-value |
|
[BP] GO:0008152 |
metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, ALPL, AOX1, APEX1, AURKB, AXL, BCL2, CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, IGF1R, INSR, KDR, MAOA, MET, MMP1, MMP12, MMP2, MMP9, NQO2, NUAK1, PIM1, PPARA, PTGES, PTPN1, RORC, SMAD3, SRC, TBXAS1, TEK, TNKS, TNKS2, TOP1, TOP2A, TRPV1, TYR, XDH |
12.3368 |
|
[BP] GO:1901700 |
response to oxygen-containing compound
|
AKR1B1, ALPL, APEX1, AXL, BCL2, CA9, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESRRA, FABP3, HSD11B2, HSD17B2, IGF1R, INSR, MMP2, MMP9, PPARA, PTGES, RORC, SRC, TEK, TRPV1, TYR |
12.026 |
|
[BP] GO:0010033 |
response to organic substance
|
AKR1B1, ALPL, APEX1, AXL, BCL2, CA2, CA9, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESRRA, FABP3, FABP4, FLT3, HSD11B2, HSD17B2, HSPA1A, IGF1R, INSR, KDR, MCL1, MMP2, PPARA, PTGES, RORC, SMAD3, SRC, TEK, TRPV1, TYR |
11.4702 |
|
[BP] GO:0015701 |
bicarbonate transport
|
CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9 |
10.9204 |
|
[BP] GO:0014070 |
response to organic cyclic compound
|
ALPL, APEX1, BCL2, CA2, CA9, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESRRA, FLT3, HSD11B2, PTGES, RORC, SRC, TEK, TRPV1, TYR |
10.702 |
|
[BP] GO:0019748 |
secondary metabolic process
|
AKR1B1, AKR1B10, BCL2, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, TYR |
10.3165 |
|
[BP] GO:0006629 |
lipid metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD2, EGFR, ESR1, FABP3, FABP4, FUT7, GBA2, HSD11B1, HSD11B2, HSD17B1, HSD17B2, MET, PPARA, PTGES, TBXAS1, TRPV1 |
10.2617 |
|
[BP] GO:0042221 |
response to chemical
|
AKR1B1, ALPL, APEX1, AXL, BCL2, CA2, CA9, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESRRA, FABP3, FABP4, FLT3, HSD11B2, HSD17B2, HSPA1A, IGF1R, INSR, KDR, MCL1, MMP2, MMP9, PPARA, PTGES, RORC, SMAD3, SRC, TEK, TOP1, TRPV1, TYR |
10.2191 |
|
[BP] GO:0006730 |
one-carbon metabolic process
|
CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9 |
10.1797 |
|
[BP] GO:0065008 |
regulation of biological quality
|
ACHE, ADORA1, AKR1B1, APEX1, AURKB, AXL, BCL2, CA12, CA2, CA7, CDK6, CYP19A1, CYP1A1, CYP1B1, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, F10, F3, FABP3, FABP4, FLT3, GPR35, HCAR2, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, INSR, KDR, MAOA, MCL1, MET, MTNR1B, PPARA, SMAD3, SRC, TEK, TNKS, TNKS2, TRPV1, XDH |
10.1673 |
|
[BP] GO:0010647 |
positive regulation of cell communication
|
ADORA1, AKR1B1, AXL, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, EGFR, F10, F3, FLT3, GPR35, HCAR2, HSPA1A, INSR, KDR, MCL1, MET, MMP12, MMP9, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
9.47571 |
|
[BP] GO:0023056 |
positive regulation of signaling
|
ADORA1, AKR1B1, AXL, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, EGFR, F10, F3, FLT3, GPR35, HCAR2, HSPA1A, INSR, KDR, MCL1, MET, MMP12, MMP9, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
9.44771 |
|
[BP] GO:0044237 |
cellular metabolic process
|
ACHE, AKR1B1, AKR1B10, ALOX5, ALPL, AOX1, APEX1, AURKB, AXL, BCL2, CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, HSD17B1, HSD17B2, HSPA1A, IGF1R, INSR, KDR, MAOA, MET, MMP1, MMP2, NQO2, NUAK1, PIM1, PPARA, PTGES, PTPN1, RORC, SMAD3, SRC, TBXAS1, TEK, TNKS, TNKS2, TOP1, TOP2A, TYR, XDH |
9.41239 |
|
[BP] GO:0048522 |
positive regulation of cellular process
|
ACHE, ADORA1, AKR1B1, APEX1, AURKB, AXL, BCL2, CA2, CA7, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FLT3, GPR35, HCAR2, HSPA1A, IGF1R, INSR, KDR, MCL1, MET, MMP1, MMP12, MMP2, MMP9, MTNR1A, PIM1, PPARA, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, XDH |
8.93895 |
|
[BP] GO:0008202 |
steroid metabolic process
|
AKR1B1, AKR1B10, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP2D6, ESR1, GBA2, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
8.31588 |
|
[BP] GO:0044281 |
small molecule metabolic process
|
AKR1B1, AKR1B10, ALOX5, AOX1, CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, FABP3, FUT7, GBA2, GLO1, HSPA1A, PIM1, PPARA, PTGES, TBXAS1, TYR, XDH |
8.31474 |
|
[BP] GO:0009719 |
response to endogenous stimulus
|
AKR1B1, ALPL, APEX1, BCL2, CA2, CA9, CSNK2A1, CYP1A2, DRD1, DRD5, EGFR, ESR1, ESRRA, FABP3, FLT3, HSD11B2, IGF1R, INSR, MMP2, PPARA, SMAD3, SRC, TEK, TRPV1 |
8.29196 |
|
[BP] GO:0042127 |
regulation of cell proliferation
|
ADORA1, ADORA3, AKR1B1, BCL2, CDC25B, CDK6, CSNK2A1, CYP1B1, DRD2, DRD3, EGFR, ESR1, ESRRA, F3, FABP3, FLT3, HSPA1A, IGF1R, INSR, KDR, MMP12, MMP2, MMP9, NUAK1, PIM1, PTGES, SMAD3, SRC, TEK, XDH |
8.15059 |
|
[BP] GO:0048511 |
rhythmic process
|
AXL, BCL2, CSNK2A1, DRD2, DRD3, EGFR, ESR1, MTNR1A, MTNR1B, PPARA, RORC, SRC, TOP1, TOP2A |
7.61826 |
|
[BP] GO:0048518 |
positive regulation of biological process
|
ACHE, ADORA1, AKR1B1, APEX1, AURKB, AXL, BCL2, CA2, CA7, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, GPR35, HCAR2, HSPA1A, IGF1R, INSR, KDR, MCL1, MET, MMP1, MMP12, MMP2, MMP9, MTNR1A, PIM1, PPARA, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, XDH |
7.48977 |
|
[BP] GO:0033993 |
response to lipid
|
ALPL, AXL, BCL2, CA2, CA9, CDK6, CSNK2A1, CYP1A1, CYP1A2, EGFR, ESR1, ESRRA, FABP3, FLT3, HSD11B2, HSD17B2, PTGES, RORC, SRC, TYR |
7.48821 |
|
[BP] GO:0043067 |
regulation of programmed cell death
|
ADORA1, AKR1B1, APEX1, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, EGFR, ESR1, F3, FLT3, GLO1, HCAR2, HSPA1A, IGF1R, KDR, MCL1, MET, MMP9, PIM1, PTPN1, SMAD3, SRC, TEK, TOP2A, TRPV1, XDH |
7.4689 |
|
[BP] GO:0010941 |
regulation of cell death
|
ADORA1, AKR1B1, APEX1, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, EGFR, ESR1, F3, FLT3, GLO1, HCAR2, HSPA1A, IGF1R, KDR, MCL1, MET, MMP9, PIM1, PPARA, PTPN1, SMAD3, SRC, TEK, TOP2A, TRPV1, XDH |
7.45797 |
|
[BP] GO:0009725 |
response to hormone
|
AKR1B1, ALPL, APEX1, BCL2, CA2, CA9, CSNK2A1, CYP1A2, EGFR, ESR1, ESRRA, FABP3, FLT3, HSD11B2, INSR, PPARA, SRC, TEK, TRPV1 |
7.29063 |
|
[BP] GO:0019369 |
arachidonic acid metabolic process
|
CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, PTGES, TBXAS1 |
7.21191 |
|
[BP] GO:0010646 |
regulation of cell communication
|
ACHE, ADORA1, AKR1B1, AURKB, AXL, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, F10, F3, FLT3, GPR35, HCAR2, HSPA1A, IGF1R, INSR, KDR, MCL1, MET, MMP12, MMP9, MTNR1B, NUAK1, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
7.02545 |
|
[BP] GO:0042981 |
regulation of apoptotic process
|
ADORA1, AKR1B1, APEX1, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, EGFR, ESR1, F3, FLT3, GLO1, HCAR2, HSPA1A, IGF1R, KDR, MCL1, MMP9, PIM1, PTPN1, SMAD3, SRC, TEK, TOP2A, TRPV1, XDH |
6.90936 |
|
[BP] GO:0023051 |
regulation of signaling
|
ACHE, ADORA1, AKR1B1, AURKB, AXL, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, F10, F3, FLT3, GPR35, HCAR2, HSPA1A, IGF1R, INSR, KDR, MCL1, MET, MMP12, MMP9, MTNR1B, NUAK1, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
6.87996 |
|
[BP] GO:0009967 |
positive regulation of signal transduction
|
ADORA1, AKR1B1, AXL, BCL2, CSNK2A1, CYP1B1, DRD2, DRD3, EGFR, F10, F3, FLT3, GPR35, HSPA1A, INSR, KDR, MCL1, MET, MMP12, MMP9, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
6.87181 |
|
[BP] GO:0040012 |
regulation of locomotion
|
ADORA1, ADORA3, APEX1, BCL2, CDK6, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, EGFR, F10, F3, IGF1R, INSR, KDR, MET, MMP9, SMAD3, SRC, TEK |
6.83201 |
|
[BP] GO:0032844 |
regulation of homeostatic process
|
ADORA1, AURKB, BCL2, CA2, CA7, CDK6, DRD1, DRD2, DRD3, EGFR, HCAR2, KDR, SRC, TNKS, TNKS2, TRPV1 |
6.8142 |
|
[BP] GO:0055114 |
oxidation-reduction process
|
AKR1B1, AKR1B10, ALOX5, AOX1, APEX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, HSD11B1, HSD11B2, HSD17B1, HSD17B2, MAOA, NQO2, TBXAS1, TYR, XDH |
6.8142 |
|
[BP] GO:0032501 |
multicellular organismal process
|
ADORA1, AKR1B1, AKR1B10, ALOX5, ALPL, AXL, BCL2, CYP19A1, CYP1A2, CYP1B1, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESRRB, F10, F3, FABP4, HSD11B2, HSD17B2, IGF1R, INSR, MCL1, MET, MMP1, MMP12, MMP2, MMP9, PIM1, PPARA, RORC, SMAD3, SRC, TEK, TNKS2, TOP1, TRPV1, TYR |
6.7851 |
|
[BP] GO:2000145 |
regulation of cell motility
|
ADORA1, ADORA3, APEX1, BCL2, CDK6, CYP19A1, CYP1B1, DRD1, DRD2, EGFR, F10, F3, IGF1R, INSR, KDR, MET, MMP9, SMAD3, SRC, TEK |
6.66488 |
|
[BP] GO:0033559 |
unsaturated fatty acid metabolic process
|
ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, PTGES, TBXAS1 |
6.66488 |
|
[BP] GO:0015711 |
organic anion transport
|
CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, DRD2, DRD3, FABP3, PPARA, TRPV1 |
6.66253 |
|
[BP] GO:0042493 |
response to drug
|
AKR1B1, APEX1, AXL, BCL2, CA9, CDK6, CYP1A1, CYP1B1, DRD1, DRD2, DRD3, DRD5, EGFR, FABP3, HSD11B2, KDR, SRC, TOP1, TRPV1 |
6.65945 |
|
[BP] GO:0042592 |
homeostatic process
|
ADORA1, AKR1B1, APEX1, AXL, BCL2, CA12, CA2, CA7, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, FABP3, FABP4, FLT3, GPR35, INSR, MCL1, MET, MTNR1B, SMAD3, SRC, TRPV1 |
6.49772 |
|
[BP] GO:0006690 |
icosanoid metabolic process
|
ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, PTGES, TBXAS1 |
6.43953 |
|
[BP] GO:0048523 |
negative regulation of cellular process
|
ACHE, ADORA1, ADORA3, AKR1B1, APEX1, AURKB, AXL, BCL2, CDK6, CSNK2A1, CYP19A1, CYP1B1, CYP2D6, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, GLO1, GPR35, HSPA1A, IGF1R, KDR, MCL1, MET, MMP12, MMP9, PIM1, PPARA, PTGES, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, XDH |
6.41891 |
|
[BP] GO:0030334 |
regulation of cell migration
|
ADORA1, ADORA3, APEX1, BCL2, CYP19A1, CYP1B1, DRD1, DRD2, EGFR, F10, F3, IGF1R, INSR, KDR, MET, MMP9, SMAD3, SRC, TEK |
6.35162 |
|
[BP] GO:0050896 |
response to stimulus
|
ACHE, ADORA1, ADORA3, AKR1B1, ALPL, APEX1, AURKB, AXL, BCL2, CA2, CA6, CA9, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESRRA, F10, F3, FABP3, FABP4, FLT3, HSD11B2, HSD17B2, HSPA1A, IGF1R, INSR, KDR, MCL1, MMP12, MMP2, MMP9, NUAK1, PPARA, PTGES, PTPN1, RORC, SMAD3, SRC, TEK, TOP1, TOP2A, TRPV1, TYR |
6.21845 |
|
[BP] GO:0010035 |
response to inorganic substance
|
AKR1B1, APEX1, AXL, BCL2, CA2, CYP1A1, CYP1A2, CYP1B1, DRD2, EGFR, FABP4, KDR, MMP9, PTGES, SRC |
6.13594 |
|
[BP] GO:0051270 |
regulation of cellular component movement
|
ADORA1, ADORA3, APEX1, BCL2, CDK6, CYP19A1, CYP1B1, DRD1, DRD2, EGFR, F10, F3, IGF1R, INSR, KDR, MET, MMP9, SMAD3, SRC, TEK |
6.12966 |
|
[BP] GO:0051896 |
regulation of protein kinase B signaling
|
AXL, DRD2, DRD3, EGFR, F10, F3, INSR, MET, SRC, TEK, XDH |
6.04091 |
|
[BP] GO:1902531 |
regulation of intracellular signal transduction
|
ADORA1, AKR1B1, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, DRD2, DRD3, DUSP3, EGFR, ESR1, F10, F3, FLT3, GPR35, HSPA1A, IGF1R, INSR, KDR, MCL1, MET, MMP9, NUAK1, PTPN1, SRC, TEK, XDH |
5.98774 |
|
[BP] GO:0032879 |
regulation of localization
|
ACHE, ADORA1, ADORA3, APEX1, AXL, BCL2, CA2, CA7, CDK6, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, EGFR, F10, F3, GPR35, HCAR2, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, MTNR1B, PPARA, PTPN1, SMAD3, SRC, TEK, TRPV1 |
5.97836 |
|
[BP] GO:0071704 |
organic substance metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, ALPL, AOX1, APEX1, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, IGF1R, INSR, KDR, MAOA, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIM1, PPARA, PTGES, PTPN1, RORC, SMAD3, SRC, TBXAS1, TEK, TNKS, TNKS2, TOP1, TOP2A, TRPV1, TYR, XDH |
5.9371 |
|
[BP] GO:0044238 |
primary metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, ALPL, AOX1, APEX1, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD1, DRD2, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIM1, PPARA, PTGES, PTPN1, RORC, SMAD3, SRC, TBXAS1, TEK, TNKS, TNKS2, TOP1, TOP2A, TRPV1, TYR, XDH |
5.9333 |
|
[BP] GO:0070887 |
cellular response to chemical stimulus
|
AKR1B1, ALPL, APEX1, AXL, BCL2, CDK6, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD5, EGFR, ESR1, FABP4, FLT3, HSPA1A, IGF1R, INSR, KDR, MMP2, MMP9, RORC, SMAD3, SRC, TRPV1 |
5.83183 |
|
[BP] GO:0060548 |
negative regulation of cell death
|
ADORA1, AKR1B1, AURKB, AXL, BCL2, CSNK2A1, EGFR, GLO1, HSPA1A, IGF1R, KDR, MCL1, MET, MMP9, PIM1, PPARA, PTPN1, SMAD3, SRC, TEK |
5.74151 |
|
[BP] GO:0010243 |
response to organonitrogen compound
|
AKR1B1, APEX1, DRD1, DRD2, DRD3, DRD5, EGFR, FABP3, FLT3, HSD11B2, IGF1R, INSR, MMP2, PPARA, SRC, TEK, TRPV1, TYR |
5.72689 |
|
[BP] GO:0010817 |
regulation of hormone levels
|
ACHE, ADORA1, AKR1B1, CYP19A1, CYP1A1, CYP1B1, DRD2, EGFR, ESR1, HCAR2, HSD11B1, HSD11B2, HSD17B1, HSD17B2, MTNR1B |
5.66225 |
|
[BP] GO:0044255 |
cellular lipid metabolic process
|
ACHE, AKR1B10, ALOX5, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD2, EGFR, FABP3, FABP4, FUT7, GBA2, MET, PPARA, PTGES, TBXAS1 |
5.65924 |
|
[BP] GO:0043069 |
negative regulation of programmed cell death
|
ADORA1, AKR1B1, AURKB, AXL, BCL2, CSNK2A1, EGFR, GLO1, HSPA1A, IGF1R, KDR, MCL1, MET, MMP9, PIM1, PTPN1, SMAD3, SRC, TEK |
5.63186 |
|
[BP] GO:0048584 |
positive regulation of response to stimulus
|
ADORA1, AKR1B1, AXL, BCL2, CSNK2A1, CYP1B1, DRD2, DRD3, EGFR, ESRRA, F10, F3, FABP4, FLT3, GPR35, HSPA1A, INSR, KDR, MCL1, MET, MMP12, MMP2, MMP9, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
5.60095 |
|
[BP] GO:0048513 |
animal organ development
|
ACHE, AXL, BCL2, CA2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, EGFR, ESR1, ESRRA, ESRRB, FLT3, HSD11B1, HSD17B2, INSR, KDR, PPARA, SMAD3, SRC, TEK, TYR |
5.60095 |
|
[BP] GO:1902533 |
positive regulation of intracellular signal transduction
|
ADORA1, AKR1B1, AXL, BCL2, CYP1B1, DRD2, EGFR, F10, F3, FLT3, GPR35, HSPA1A, INSR, KDR, MCL1, MET, PTPN1, SRC, TEK, XDH |
5.59072 |
|
[BP] GO:0048519 |
negative regulation of biological process
|
ACHE, ADORA1, ADORA3, AKR1B1, APEX1, AURKB, AXL, BCL2, CDK6, CSNK2A1, CYP19A1, CYP1B1, CYP2D6, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, GLO1, GPR35, HCAR2, HSPA1A, IGF1R, KDR, MCL1, MET, MMP12, MMP9, PIM1, PPARA, PTGES, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, XDH |
5.57693 |
|
[BP] GO:0042445 |
hormone metabolic process
|
ACHE, AKR1B1, CYP19A1, CYP1A1, CYP1B1, ESR1, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
5.55457 |
|
[BP] GO:0008284 |
positive regulation of cell proliferation
|
AKR1B1, BCL2, CDC25B, CDK6, CSNK2A1, DRD2, DRD3, EGFR, ESR1, F3, FLT3, IGF1R, INSR, KDR, MMP12, MMP2, MMP9, PIM1, TEK |
5.53601 |
|
[BP] GO:0017144 |
drug metabolic process
|
ACHE, AKR1B1, AKR1B10, AOX1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP2D6, DRD1, DRD2, DRD3, EGFR, HSPA1A, MAOA |
5.50266 |
|
[BP] GO:0009698 |
phenylpropanoid metabolic process
|
CYP1A1, CYP2A13, CYP2A6, CYP2D6 |
5.48767 |
|
[BP] GO:0009804 |
coumarin metabolic process
|
CYP1A1, CYP2A13, CYP2A6, CYP2D6 |
5.48767 |
|
[BP] GO:0051173 |
positive regulation of nitrogen compound metabolic process
|
ADORA1, AURKB, BCL2, CDC25B, CSNK2A1, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, MTNR1A, PPARA, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, XDH |
5.48514 |
|
[BP] GO:0071310 |
cellular response to organic substance
|
AKR1B1, ALPL, APEX1, AXL, BCL2, CDK6, CYP1A1, CYP1B1, DRD1, DRD5, EGFR, ESR1, FABP4, FLT3, IGF1R, INSR, KDR, MMP2, RORC, SMAD3, SRC, TRPV1 |
5.45578 |
|
[BP] GO:0001676 |
long-chain fatty acid metabolic process
|
CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, PTGES, TBXAS1 |
5.41622 |
|
[BP] GO:0046777 |
protein autophosphorylation
|
AURKB, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KDR, PIM1, SRC, TEK |
5.3592 |
|
[BP] GO:0006820 |
anion transport
|
CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, DRD2, DRD3, FABP3, PPARA, TRPV1 |
5.3534 |
|
[BP] GO:1901698 |
response to nitrogen compound
|
AKR1B1, APEX1, DRD1, DRD2, DRD3, DRD5, EGFR, FABP3, FLT3, HSD11B2, IGF1R, INSR, MMP2, PPARA, SRC, TEK, TRPV1, TYR |
5.30785 |
|
[BP] GO:0032502 |
developmental process
|
ACHE, ADORA1, AKR1B1, ALPL, APEX1, AURKB, AXL, BCL2, CA2, CA9, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DUSP3, EGFR, ESR1, ESRRA, ESRRB, FABP4, FLT3, FUT7, GBA2, GLO1, HSD11B1, HSD17B2, INSR, KDR, MCL1, MET, MMP2, MMP9, PIM1, PPARA, RORC, SMAD3, SRC, TEK, TNKS2, TOP2A, TYR |
5.25305 |
|
[BP] GO:0006468 |
protein phosphorylation
|
AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, EGFR, FLT3, IGF1R, INSR, KDR, MET, NUAK1, PIM1, SRC, TEK, TNKS, TOP1 |
5.19704 |
|
[BP] GO:0009636 |
response to toxic substance
|
AKR1B1, ALPL, APEX1, AXL, BCL2, CYP1A1, CYP1B1, DRD1, DRD2, DRD3, DRD5, KDR, SRC |
5.19451 |
|
[BP] GO:0019373 |
epoxygenase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6 |
5.15817 |
|
[BP] GO:0048878 |
chemical homeostasis
|
AKR1B1, BCL2, CA12, CA2, CA7, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, FABP3, FABP4, GPR35, INSR, MET, MTNR1B, SMAD3, TRPV1 |
5.15817 |
|
[BP] GO:2000021 |
regulation of ion homeostasis
|
ADORA1, BCL2, CA2, CA7, DRD1, DRD2, DRD3, KDR, SRC, TRPV1 |
5.15817 |
|
[BP] GO:1901568 |
fatty acid derivative metabolic process
|
ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, PTGES, TBXAS1 |
5.15817 |
|
[BP] GO:0031325 |
positive regulation of cellular metabolic process
|
ADORA1, AURKB, BCL2, CDC25B, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, MTNR1A, PPARA, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, XDH |
5.12416 |
|
[BP] GO:0010648 |
negative regulation of cell communication
|
ACHE, ADORA1, BCL2, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, GPR35, HSPA1A, IGF1R, MCL1, MET, MMP12, MMP9, PTPN1, SMAD3, SRC, XDH |
5.10182 |
|
[BP] GO:1901564 |
organonitrogen compound metabolic process
|
ACHE, AKR1B1, ALPL, AOX1, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP2D6, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, F10, F3, FLT3, FUT7, GBA2, GLO1, HSPA1A, IGF1R, INSR, KDR, MAOA, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIM1, PPARA, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1, TOP2A, TYR, XDH |
5.09734 |
|
[BP] GO:0043066 |
negative regulation of apoptotic process
|
ADORA1, AKR1B1, AURKB, AXL, BCL2, CSNK2A1, EGFR, GLO1, HSPA1A, IGF1R, KDR, MCL1, MMP9, PIM1, PTPN1, SMAD3, SRC, TEK |
5.09152 |
|
[BP] GO:0023057 |
negative regulation of signaling
|
ACHE, ADORA1, BCL2, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, GPR35, HSPA1A, IGF1R, MCL1, MET, MMP12, MMP9, PTPN1, SMAD3, SRC, XDH |
5.09009 |
|
[BP] GO:0051716 |
cellular response to stimulus
|
AKR1B1, ALPL, APEX1, AURKB, AXL, BCL2, CA2, CA9, CDK6, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD5, EGFR, ESR1, FABP4, FLT3, HSPA1A, IGF1R, INSR, KDR, MCL1, MMP2, MMP9, NUAK1, PTPN1, RORC, SMAD3, SRC, TOP2A, TRPV1 |
4.99478 |
|
[BP] GO:0071407 |
cellular response to organic cyclic compound
|
ALPL, APEX1, CYP1A1, CYP1B1, DRD1, DRD5, EGFR, ESR1, FLT3, RORC, SRC, TRPV1 |
4.95812 |
|
[BP] GO:0018958 |
None
|
AKR1B1, BCL2, DRD1, DRD2, DRD3, MAOA, TYR |
4.93314 |
|
[BP] GO:0006796 |
phosphate-containing compound metabolic process
|
ACHE, ALPL, APEX1, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, DRD2, DUSP3, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIM1, PTPN1, SRC, TEK, TNKS, TOP1, XDH |
4.86843 |
|
[BP] GO:0032846 |
positive regulation of homeostatic process
|
AURKB, CA2, CA7, DRD1, DRD2, DRD3, EGFR, HCAR2, TNKS, TNKS2 |
4.86292 |
|
[BP] GO:0009893 |
positive regulation of metabolic process
|
ADORA1, AURKB, BCL2, CDC25B, CSNK2A1, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, MTNR1A, PPARA, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, XDH |
4.84949 |
|
[BP] GO:0009628 |
response to abiotic stimulus
|
ADORA1, AKR1B1, AURKB, BCL2, CA2, CYP1A1, DRD1, DRD2, DRD3, EGFR, HSD11B2, HSPA1A, MMP2, PPARA, SMAD3, SRC, TEK, TRPV1, TYR |
4.80945 |
|
[BP] GO:0030335 |
positive regulation of cell migration
|
BCL2, DRD1, EGFR, F10, F3, IGF1R, INSR, KDR, MET, MMP9, SMAD3, SRC, TEK |
4.79816 |
|
[BP] GO:0006631 |
fatty acid metabolic process
|
ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, FABP3, PPARA, PTGES, TBXAS1 |
4.78411 |
|
[BP] GO:0019220 |
regulation of phosphate metabolic process
|
ADORA1, BCL2, CDC25B, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESRRB, FABP3, FABP4, FLT3, IGF1R, INSR, KDR, MMP9, MTNR1A, NUAK1, PPARA, PTPN1, SMAD3, SRC, TEK, XDH |
4.70863 |
|
[BP] GO:0048585 |
negative regulation of response to stimulus
|
ADORA1, BCL2, CDK6, CYP19A1, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, HSPA1A, IGF1R, MCL1, MET, MMP12, MMP9, PPARA, PTPN1, SMAD3, SRC, TEK, XDH |
4.70094 |
|
[BP] GO:0009611 |
response to wounding
|
ACHE, ADORA3, BCL2, CYP1A1, DRD2, DRD5, EGFR, PPARA, SMAD3 |
4.70008 |
|
[BP] GO:0051174 |
regulation of phosphorus metabolic process
|
ADORA1, BCL2, CDC25B, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESRRB, FABP3, FABP4, FLT3, IGF1R, INSR, KDR, MMP9, MTNR1A, NUAK1, PPARA, PTPN1, SMAD3, SRC, TEK, XDH |
4.65886 |
|
[BP] GO:2000147 |
positive regulation of cell motility
|
BCL2, DRD1, EGFR, F10, F3, IGF1R, INSR, KDR, MET, MMP9, SMAD3, SRC, TEK |
4.65142 |
|
[BP] GO:0048856 |
anatomical structure development
|
ACHE, ADORA1, AKR1B1, ALPL, AXL, BCL2, CA2, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DUSP3, EGFR, ESR1, ESRRA, ESRRB, FLT3, GBA2, HSD11B1, HSD17B2, INSR, KDR, MCL1, MMP9, PIM1, PPARA, RORC, SMAD3, SRC, TEK, TYR |
4.60859 |
|
[BP] GO:0018108 |
peptidyl-tyrosine phosphorylation
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, SRC, TEK |
4.57836 |
|
[BP] GO:0007623 |
circadian rhythm
|
DRD2, DRD3, EGFR, MTNR1A, MTNR1B, PPARA, RORC, TOP1 |
4.53536 |
|
[BP] GO:0006793 |
phosphorus metabolic process
|
ACHE, ALPL, APEX1, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, DRD2, DUSP3, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIM1, PTPN1, SRC, TEK, TNKS, TOP1, XDH |
4.53536 |
|
[BP] GO:0018212 |
peptidyl-tyrosine modification
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, SRC, TEK |
4.53536 |
|
[BP] GO:0051272 |
positive regulation of cellular component movement
|
BCL2, DRD1, EGFR, F10, F3, IGF1R, INSR, KDR, MET, MMP9, SMAD3, SRC, TEK |
4.53536 |
|
[BP] GO:0044092 |
negative regulation of molecular function
|
ADORA3, AURKB, CSNK2A1, CYP1B1, CYP2D6, DRD2, DRD3, DRD5, DUSP3, ESR1, FABP4, GPR35, IGF1R, MET, MMP9, PIM1, PPARA, PTPN1, SRC, TNKS |
4.53536 |
|
[BP] GO:0048583 |
regulation of response to stimulus
|
ADORA1, AKR1B1, AURKB, AXL, BCL2, CDK6, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, F10, F3, FABP4, FLT3, GPR35, HSPA1A, IGF1R, INSR, KDR, MCL1, MET, MMP12, MMP2, MMP9, NUAK1, PPARA, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
4.50196 |
|
[BP] GO:0032787 |
None
|
ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, FABP3, GBA2, GLO1, PPARA, PTGES, TBXAS1 |
4.46686 |
|
[BP] GO:0001505 |
regulation of neurotransmitter levels
|
ACHE, CYP1B1, DRD1, DRD2, DRD3, EGFR, INSR, MAOA, SMAD3, TRPV1 |
4.46672 |
|
[BP] GO:1901701 |
cellular response to oxygen-containing compound
|
AKR1B1, APEX1, AXL, CDK6, CYP1B1, DRD1, DRD5, EGFR, ESR1, IGF1R, INSR, MMP2, MMP9, RORC, SRC, TRPV1 |
4.46308 |
|
[BP] GO:0007346 |
regulation of mitotic cell cycle
|
APEX1, AURKB, BCL2, CDC25B, CDK6, CYP1A1, DRD3, DUSP3, EGFR, HSPA1A, INSR, PIM1, SMAD3, TNKS, TOP2A |
4.45199 |
|
[BP] GO:0009891 |
positive regulation of biosynthetic process
|
AURKB, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, IGF1R, INSR, KDR, MET, MMP12, MTNR1A, PPARA, RORC, SMAD3, SRC, TNKS, TNKS2, TOP2A, TRPV1 |
4.44703 |
|
[BP] GO:0001666 |
response to hypoxia
|
ADORA1, BCL2, CYP1A1, DRD2, HSD11B2, MMP2, PPARA, SMAD3, SRC, TEK |
4.41639 |
|
[BP] GO:0040017 |
positive regulation of locomotion
|
BCL2, DRD1, EGFR, F10, F3, IGF1R, INSR, KDR, MET, MMP9, SMAD3, SRC, TEK |
4.39869 |
|
[BP] GO:0007165 |
signal transduction
|
ADORA1, ADORA3, AKR1B1, AXL, BCL2, CA1, CA2, CDK6, CSNK2A1, CYP1B1, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, HCAR2, IGF1R, INSR, KDR, MCL1, MET, MMP2, MMP9, MTNR1A, MTNR1B, NUAK1, PIM1, PPARA, PTGES, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TRPV1 |
4.35342 |
|
[BP] GO:0042446 |
hormone biosynthetic process
|
AKR1B1, CYP19A1, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
4.33416 |
|
[BP] GO:0018193 |
peptidyl-amino acid modification
|
AURKB, AXL, BCL2, CSNK2A1, DRD1, EGFR, F10, FLT3, IGF1R, INSR, KDR, MET, SRC, TEK, TNKS, TOP1, TOP2A |
4.32261 |
|
[BP] GO:1901615 |
organic hydroxy compound metabolic process
|
AKR1B1, AKR1B10, BCL2, CYP19A1, CYP1A1, CYP1B1, DRD1, DRD2, DRD3, GBA2, MAOA, TYR |
4.32083 |
|
[BP] GO:0036293 |
response to decreased oxygen levels
|
ADORA1, BCL2, CYP1A1, DRD2, HSD11B2, MMP2, PPARA, SMAD3, SRC, TEK |
4.31795 |
|
[BP] GO:0032847 |
regulation of cellular pH reduction
|
BCL2, CA2, CA7 |
4.30317 |
|
[BP] GO:0010562 |
positive regulation of phosphorus metabolic process
|
ADORA1, BCL2, CDC25B, DRD1, DRD2, DRD5, EGFR, ESRRB, FABP3, FLT3, INSR, KDR, MMP9, MTNR1A, PTPN1, SMAD3, SRC, TEK, XDH |
4.29971 |
|
[BP] GO:0045937 |
positive regulation of phosphate metabolic process
|
ADORA1, BCL2, CDC25B, DRD1, DRD2, DRD5, EGFR, ESRRB, FABP3, FLT3, INSR, KDR, MMP9, MTNR1A, PTPN1, SMAD3, SRC, TEK, XDH |
4.29971 |
|
[BP] GO:0080134 |
regulation of response to stress
|
ADORA1, CDK6, CYP19A1, DRD2, DUSP3, EGFR, ESR1, F3, FABP4, HSPA1A, IGF1R, MCL1, MET, MMP12, MMP2, NUAK1, PPARA, PTPN1, SMAD3, SRC, TEK, XDH |
4.28865 |
|
[BP] GO:0045935 |
positive regulation of nucleobase-containing compound metabolic process
|
AURKB, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESR2, ESRRA, ESRRB, HSPA1A, IGF1R, INSR, MET, MMP12, MTNR1A, PPARA, PTPN1, RORC, SMAD3, SRC, TNKS, TNKS2, TOP2A |
4.27974 |
|
[BP] GO:0051897 |
positive regulation of protein kinase B signaling
|
AXL, EGFR, F10, F3, INSR, MET, SRC, TEK |
4.24066 |
|
[BP] GO:0065009 |
regulation of molecular function
|
ADORA1, ADORA3, AURKB, BCL2, CDC25B, CSNK2A1, CYP1B1, CYP2D6, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, F3, FABP4, FLT3, GPR35, HSPA1A, IGF1R, INSR, MET, MMP9, NUAK1, PIM1, PPARA, PTPN1, SMAD3, SRC, TEK, TNKS, TRPV1, XDH |
4.18246 |
|
[BP] GO:0001963 |
None
|
DRD1, DRD2, DRD3, DRD5 |
4.16869 |
|
[BP] GO:1902532 |
negative regulation of intracellular signal transduction
|
BCL2, DRD2, DRD3, DUSP3, ESR1, HSPA1A, IGF1R, MCL1, MET, MMP9, PTPN1, SRC, XDH |
4.15626 |
|
[BP] GO:0035690 |
cellular response to drug
|
AKR1B1, APEX1, AXL, CDK6, CYP1B1, DRD1, EGFR, KDR, SRC, TRPV1 |
4.13575 |
|
[BP] GO:0034754 |
cellular hormone metabolic process
|
AKR1B1, CYP19A1, CYP1A1, CYP1B1, ESR1, HSD17B1, HSD17B2 |
4.13306 |
|
[BP] GO:0034614 |
cellular response to reactive oxygen species
|
AKR1B1, APEX1, AXL, CYP1B1, EGFR, MMP9, SRC |
4.13306 |
|
[BP] GO:0009892 |
negative regulation of metabolic process
|
ADORA1, APEX1, AURKB, BCL2, CSNK2A1, CYP2D6, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, ESRRA, FABP4, HCAR2, HSPA1A, IGF1R, KDR, MCL1, MET, MMP12, MMP9, PPARA, PTPN1, RORC, SMAD3, SRC, TNKS, TNKS2, TRPV1, XDH |
4.10903 |
|
[BP] GO:0031328 |
positive regulation of cellular biosynthetic process
|
AURKB, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, IGF1R, INSR, MET, MMP12, MTNR1A, PPARA, RORC, SMAD3, SRC, TNKS, TNKS2, TOP2A, TRPV1 |
4.05 |
|
[BP] GO:0016310 |
phosphorylation
|
AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, EGFR, FLT3, IGF1R, INSR, KDR, MET, NUAK1, PIM1, SRC, TEK, TNKS, TOP1 |
4.04188 |
|
[BP] GO:0070482 |
response to oxygen levels
|
ADORA1, BCL2, CYP1A1, DRD2, HSD11B2, MMP2, PPARA, SMAD3, SRC, TEK |
4.0268 |
|
[BP] GO:0006805 |
xenobiotic metabolic process
|
CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2D6, NQO2, RORC |
3.98626 |
|
[BP] GO:0009966 |
regulation of signal transduction
|
ADORA1, AKR1B1, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, F10, F3, FLT3, GPR35, HSPA1A, IGF1R, INSR, KDR, MCL1, MET, MMP12, MMP9, NUAK1, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, XDH |
3.96486 |
|
[BP] GO:0009987 |
cellular process
|
ACHE, ADORA1, ADORA3, AKR1B1, AKR1B10, ALOX5, ALPL, AOX1, APEX1, AURKB, AXL, BCL2, CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, GPR35, HCAR2, HSD17B1, HSD17B2, HSPA1A, IGF1R, INSR, KDR, MAOA, MCL1, MET, MMP1, MMP12, MMP2, MMP9, MTNR1A, MTNR1B, NQO2, NUAK1, PIM1, PPARA, PTGES, PTPN1, RORC, SMAD3, SRC, TBXAS1, TEK, TNKS, TNKS2, TOP1, TOP2A, TRPV1, TYR, XDH |
3.90973 |
|
[BP] GO:0000302 |
response to reactive oxygen species
|
AKR1B1, APEX1, AXL, BCL2, CYP1B1, EGFR, MMP9, SRC |
3.83677 |
|
[BP] GO:0009056 |
catabolic process
|
ACHE, ADORA1, AKR1B10, AOX1, AURKB, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP2D6, FABP3, FABP4, FUT7, GBA2, HSPA1A, MAOA, MMP1, MMP12, MMP2, MMP9, SRC, XDH |
3.83429 |
|
[BP] GO:0030522 |
intracellular receptor signaling pathway
|
ESR1, ESR2, ESRRA, ESRRB, PIM1, PPARA, RORC, SRC |
3.82572 |
|
[BP] GO:0045776 |
None
|
ADORA1, DRD2, DRD3, DRD5, PPARA |
3.82572 |
|
[BP] GO:0019222 |
regulation of metabolic process
|
ACHE, ADORA1, ADORA3, APEX1, AURKB, BCL2, CA9, CDC25B, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GLO1, HCAR2, HSPA1A, IGF1R, INSR, KDR, MCL1, MET, MMP12, MMP9, MTNR1A, NUAK1, PIM1, PPARA, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1, TOP2A, TRPV1, XDH |
3.82572 |
|
[BP] GO:0006584 |
None
|
AKR1B1, DRD1, DRD2, DRD3, MAOA |
3.77967 |
|
[BP] GO:0009712 |
None
|
AKR1B1, DRD1, DRD2, DRD3, MAOA |
3.77967 |
|
[BP] GO:0097164 |
None
|
ACHE, AKR1B1, AKR1B10, CSNK2A1, DRD1, DRD2, DRD3, MAOA |
3.70703 |
|
[BP] GO:0050801 |
ion homeostasis
|
BCL2, CA12, CA2, CA7, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, FABP3, GPR35, SMAD3, TRPV1 |
3.70665 |
|
[BP] GO:0050790 |
regulation of catalytic activity
|
ADORA1, ADORA3, AURKB, BCL2, CDC25B, CSNK2A1, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, F3, FABP4, FLT3, HSPA1A, IGF1R, INSR, MMP9, NUAK1, PTPN1, SMAD3, SRC, TEK, TNKS, XDH |
3.69803 |
|
[BP] GO:0010604 |
positive regulation of macromolecule metabolic process
|
ADORA1, AURKB, BCL2, CDC25B, CSNK2A1, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, PPARA, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, XDH |
3.6511 |
|
[BP] GO:0022414 |
reproductive process
|
AKR1B1, ALPL, AXL, BCL2, CDC25B, CYP19A1, CYP1A1, DRD1, DRD5, EGFR, ESR1, ESRRB, HSD11B2, HSD17B2, INSR, MMP2, MMP9, MTNR1A, SRC, TOP2A |
3.6511 |
|
[BP] GO:0043401 |
steroid hormone mediated signaling pathway
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC, SRC |
3.64496 |
|
[BP] GO:0032101 |
regulation of response to external stimulus
|
ADORA1, CYP19A1, DRD1, DRD2, DRD3, EGFR, ESR1, F3, FABP4, KDR, MET, MMP12, PPARA, SMAD3, TEK |
3.63355 |
|
[BP] GO:0038083 |
peptidyl-tyrosine autophosphorylation
|
EGFR, IGF1R, INSR, KDR, SRC |
3.61118 |
|
[BP] GO:0007169 |
transmembrane receptor protein tyrosine kinase signaling pathway
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, MMP2, MMP9, PTPN1, SRC, TEK |
3.57786 |
|
[BP] GO:0034599 |
cellular response to oxidative stress
|
AKR1B1, APEX1, AXL, CYP1B1, EGFR, HSPA1A, MMP9, SRC |
3.53414 |
|
[BP] GO:0010638 |
positive regulation of organelle organization
|
AURKB, BCL2, DRD3, HSPA1A, INSR, KDR, MET, MMP9, SMAD3, SRC, TEK, TNKS, TNKS2 |
3.4009 |
|
[BP] GO:0051726 |
regulation of cell cycle
|
APEX1, AURKB, BCL2, CDC25B, CDK6, CSNK2A1, CYP1A1, DRD2, DRD3, DUSP3, EGFR, HSPA1A, INSR, PIM1, SMAD3, SRC, TNKS, TOP2A |
3.39101 |
|
[BP] GO:1901652 |
response to peptide
|
AKR1B1, APEX1, FABP3, HSD11B2, IGF1R, INSR, PPARA, SRC, TEK, TRPV1 |
3.39101 |
|
[BP] GO:0008210 |
estrogen metabolic process
|
CYP19A1, CYP1B1, HSD17B1, HSD17B2 |
3.39101 |
|
[BP] GO:0032845 |
None
|
ADORA1, BCL2, DRD2, SRC, TNKS, TNKS2, TRPV1 |
3.37974 |
|
[BP] GO:0051130 |
positive regulation of cellular component organization
|
AURKB, AXL, BCL2, DRD2, DRD3, ESR1, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP9, SMAD3, SRC, TEK, TNKS, TNKS2 |
3.37453 |
|
[BP] GO:2001243 |
negative regulation of intrinsic apoptotic signaling pathway
|
BCL2, HSPA1A, MCL1, MMP9, PTPN1, SRC |
3.33462 |
|
[BP] GO:0032922 |
None
|
DRD2, DRD3, PPARA, RORC, TOP1 |
3.3002 |
|
[BP] GO:0051940 |
None
|
DRD1, DRD2, DRD3 |
3.29948 |
|
[BP] GO:0051584 |
None
|
DRD1, DRD2, DRD3 |
3.29948 |
|
[BP] GO:0008217 |
None
|
ADORA1, DRD2, DRD3, DRD5, HSD11B2, PPARA, SMAD3 |
3.29623 |
|
[BP] GO:0042752 |
None
|
ADORA1, DRD2, DRD3, PPARA, RORC, TOP2A |
3.2665 |
|
[BP] GO:0001975 |
None
|
DRD1, DRD2, DRD3, DRD5 |
3.2665 |
|
[BP] GO:0019216 |
regulation of lipid metabolic process
|
ADORA1, CYP1A1, DRD3, FABP3, FLT3, HCAR2, PPARA, RORC, SRC, TEK |
3.26406 |
|
[BP] GO:0051049 |
regulation of transport
|
ACHE, ADORA1, AXL, BCL2, CA2, CA7, CYP19A1, DRD1, DRD2, DRD3, EGFR, GPR35, HCAR2, HSPA1A, INSR, MMP12, MMP9, MTNR1B, PPARA, PTPN1, SMAD3, SRC, TRPV1 |
3.26126 |
|
[BP] GO:0051050 |
positive regulation of transport
|
ACHE, ADORA1, AXL, BCL2, CA2, CYP19A1, DRD1, DRD2, DRD3, EGFR, HCAR2, INSR, MMP12, SMAD3, SRC, TRPV1 |
3.24676 |
|
[BP] GO:0098771 |
inorganic ion homeostasis
|
BCL2, CA12, CA2, CA7, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, GPR35, SMAD3, TRPV1 |
3.2363 |
|
[BP] GO:0019752 |
carboxylic acid metabolic process
|
ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, FABP3, GBA2, GLO1, PIM1, PPARA, PTGES, TBXAS1, TYR |
3.20614 |
|
[BP] GO:0007166 |
cell surface receptor signaling pathway
|
ADORA1, ADORA3, AXL, BCL2, CA1, CSNK2A1, DRD2, EGFR, F3, FLT3, GPR35, IGF1R, INSR, KDR, MCL1, MET, MMP2, MMP9, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TRPV1 |
3.20586 |
|
[BP] GO:0045787 |
positive regulation of cell cycle
|
APEX1, AURKB, CDC25B, CYP1A1, DRD2, DRD3, DUSP3, EGFR, INSR, SRC |
3.1987 |
|
[BP] GO:0072593 |
reactive oxygen species metabolic process
|
BCL2, CYP1A1, CYP1A2, CYP1B1, DRD5, EGFR |
3.18951 |
|
[BP] GO:0001952 |
regulation of cell-matrix adhesion
|
BCL2, CDK6, KDR, SMAD3, SRC, TEK |
3.16693 |
|
[BP] GO:0042417 |
None
|
DRD1, DRD2, DRD3, MAOA |
3.16036 |
|
[BP] GO:0051701 |
interaction with host
|
AXL, EGFR, HSPA1A, INSR, MET, SMAD3, SRC |
3.16036 |
|
[BP] GO:0006950 |
response to stress
|
ACHE, ADORA1, ADORA3, AKR1B1, APEX1, AXL, BCL2, CA2, CA9, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DRD5, EGFR, HSD11B2, HSPA1A, MCL1, MMP2, MMP9, NUAK1, PPARA, PTGES, PTPN1, SMAD3, SRC, TEK, TOP2A, TRPV1 |
3.10944 |
|
[BP] GO:0051047 |
None
|
ACHE, ADORA1, CYP19A1, DRD2, DRD3, EGFR, HCAR2, MMP12, SRC, TRPV1 |
3.10481 |
|
[BP] GO:0050804 |
modulation of chemical synaptic transmission
|
ACHE, ADORA1, CA2, CA7, DRD1, DRD2, DRD3, DRD5, EGFR |
3.10329 |
|
[BP] GO:0099177 |
regulation of trans-synaptic signaling
|
ACHE, ADORA1, CA2, CA7, DRD1, DRD2, DRD3, DRD5, EGFR |
3.10329 |
|
[BP] GO:0006721 |
terpenoid metabolic process
|
AKR1B10, CYP1A1, CYP1A2, CYP1B1, CYP2D6, EGFR |
3.09024 |
|
[BP] GO:0042542 |
response to hydrogen peroxide
|
AKR1B1, APEX1, AXL, BCL2, CYP1B1, SRC |
3.07064 |
|
[BP] GO:0007167 |
enzyme linked receptor protein signaling pathway
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, MMP2, MMP9, PTPN1, SMAD3, SRC, TEK |
3.04993 |
|
[BP] GO:0050805 |
negative regulation of synaptic transmission
|
ACHE, ADORA1, DRD1, DRD2, DRD5 |
3.03328 |
|
[BP] GO:0007191 |
None
|
DRD1, DRD3, DRD5 |
3.03085 |
|
[BP] GO:0097267 |
omega-hydroxylase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1 |
3.03085 |
|
[BP] GO:0009755 |
hormone-mediated signaling pathway
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC, SRC |
3.03033 |
|
[BP] GO:1900542 |
None
|
DRD1, DRD2, DRD3, DRD5, ESRRB, INSR, MTNR1A, PPARA |
3.02583 |
|
[BP] GO:0031347 |
regulation of defense response
|
ADORA1, CYP19A1, DRD2, EGFR, ESR1, FABP4, HSPA1A, MMP12, MMP2, PPARA, PTPN1, SMAD3, SRC, TEK |
3.01464 |
|
[BP] GO:0001659 |
None
|
ADORA1, DRD1, DRD2, TRPV1 |
3.0113 |
|
[BP] GO:2000377 |
regulation of reactive oxygen species metabolic process
|
BCL2, CYP1B1, EGFR, INSR, SMAD3, TRPV1, XDH |
3.00647 |
|
[BP] GO:0071417 |
cellular response to organonitrogen compound
|
AKR1B1, APEX1, DRD1, DRD5, EGFR, IGF1R, INSR, MMP2, SRC, TRPV1 |
3.00647 |
|
[BP] GO:0071495 |
cellular response to endogenous stimulus
|
AKR1B1, APEX1, DRD1, DRD5, EGFR, ESR1, FLT3, IGF1R, INSR, MMP2, SMAD3, SRC, TRPV1 |
3.00647 |
|
[BP] GO:0031348 |
negative regulation of defense response
|
ADORA1, CYP19A1, DRD2, MMP12, PPARA, SMAD3, TEK |
2.97569 |
|
[BP] GO:0051240 |
positive regulation of multicellular organismal process
|
AXL, BCL2, CA2, CYP1B1, DRD2, DRD3, EGFR, ESRRB, F3, HCAR2, HSPA1A, KDR, MET, MMP12, MMP9, PIM1, SMAD3, SRC, TEK, TRPV1 |
2.96961 |
|
[BP] GO:0032228 |
regulation of synaptic transmission, GABAergic
|
ADORA1, CA2, CA7, DRD2 |
2.96699 |
|
[BP] GO:0001503 |
ossification
|
ALPL, BCL2, EGFR, MMP2, MMP9, TEK |
2.96408 |
|
[BP] GO:0051239 |
regulation of multicellular organismal process
|
ADORA1, ADORA3, AXL, BCL2, CA2, CDK6, CYP1B1, DRD2, DRD3, EGFR, ESR1, ESRRA, ESRRB, F3, GPR35, HCAR2, HSPA1A, INSR, KDR, MET, MMP12, MMP9, PIM1, SMAD3, SRC, TEK, TNKS2, TRPV1, XDH |
2.96071 |
|
[BP] GO:0006140 |
None
|
DRD1, DRD2, DRD3, DRD5, ESRRB, INSR, MTNR1A, PPARA |
2.95549 |
|
[BP] GO:0009894 |
regulation of catabolic process
|
ADORA1, APEX1, BCL2, CSNK2A1, EGFR, ESRRB, HCAR2, HSPA1A, INSR, KDR, MCL1, MET, PPARA, PTPN1, SMAD3 |
2.94723 |
|
[BP] GO:0010038 |
response to metal ion
|
BCL2, CA2, CYP1A1, CYP1A2, DRD2, EGFR, FABP4, MMP9, PTGES |
2.94405 |
|
[BP] GO:0010907 |
None
|
ESRRB, INSR, PPARA, SRC |
2.92421 |
|
[BP] GO:0048871 |
multicellular organismal homeostasis
|
ADORA1, AKR1B1, DRD1, DRD2, MET, TRPV1 |
2.89025 |
|
[BP] GO:0031323 |
regulation of cellular metabolic process
|
ACHE, ADORA1, ADORA3, APEX1, AURKB, BCL2, CA9, CDC25B, CSNK2A1, CYP1B1, CYP2D6, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GLO1, HSPA1A, IGF1R, INSR, KDR, MCL1, MET, MMP12, MMP9, MTNR1A, NUAK1, PIM1, PPARA, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, XDH |
2.88927 |
|
[BP] GO:0050806 |
positive regulation of synaptic transmission
|
ADORA1, CA2, CA7, DRD1, DRD2, EGFR |
2.83306 |
|
[BP] GO:0021885 |
forebrain cell migration
|
AXL, DRD1, DRD2, EGFR |
2.8284 |
|
[BP] GO:0072507 |
divalent inorganic cation homeostasis
|
BCL2, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, GPR35, SMAD3, TRPV1 |
2.82381 |
|
[BP] GO:0007187 |
None
|
ADORA1, DRD1, DRD2, DRD3, DRD5, MTNR1A, MTNR1B |
2.81474 |
|
[BP] GO:0009968 |
negative regulation of signal transduction
|
BCL2, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, HSPA1A, IGF1R, MCL1, MET, MMP12, MMP9, PTPN1, SMAD3, SRC, XDH |
2.81474 |
|
[BP] GO:0010564 |
regulation of cell cycle process
|
APEX1, AURKB, BCL2, CDC25B, CDK6, CSNK2A1, CYP1A1, DRD2, DRD3, EGFR, HSPA1A, INSR, TNKS |
2.80469 |
|
[BP] GO:0046960 |
None
|
DRD1, DRD5 |
2.80075 |
|
[BP] GO:0009115 |
None
|
AOX1, XDH |
2.80075 |
|
[BP] GO:0043436 |
oxoacid metabolic process
|
ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, FABP3, GBA2, GLO1, PIM1, PPARA, PTGES, TBXAS1, TYR |
2.79239 |
|
[BP] GO:0006720 |
isoprenoid metabolic process
|
AKR1B10, CYP1A1, CYP1A2, CYP1B1, CYP2D6, EGFR |
2.77521 |
|
[BP] GO:0006694 |
steroid biosynthetic process
|
AKR1B1, CYP19A1, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
2.75816 |
|
[BP] GO:1901699 |
cellular response to nitrogen compound
|
AKR1B1, APEX1, DRD1, DRD5, EGFR, IGF1R, INSR, MMP2, SRC, TRPV1 |
2.75816 |
|
[BP] GO:0007212 |
None
|
DRD1, DRD2, DRD3, DRD5 |
2.75755 |
|
[BP] GO:0032467 |
None
|
AURKB, CDC25B, DRD2, DRD3 |
2.75755 |
|
[BP] GO:0044093 |
positive regulation of molecular function
|
ADORA1, AURKB, BCL2, CDC25B, DRD2, DRD5, EGFR, ESR1, ESR2, F3, FLT3, HSPA1A, INSR, MET, MMP9, PTPN1, SMAD3, SRC, TEK, TNKS, XDH |
2.73813 |
|
[BP] GO:0006979 |
response to oxidative stress
|
AKR1B1, APEX1, AXL, BCL2, CYP1B1, EGFR, HSPA1A, MMP9, SRC |
2.73813 |
|
[BP] GO:0051098 |
regulation of binding
|
AURKB, BCL2, CYP2D6, MET, MMP9, PPARA, SMAD3, SRC, TNKS |
2.73813 |
|
[BP] GO:0055080 |
cation homeostasis
|
BCL2, CA2, CA7, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, GPR35, SMAD3, TRPV1 |
2.7365 |
|
[BP] GO:0006703 |
estrogen biosynthetic process
|
CYP19A1, HSD17B1, HSD17B2 |
2.7365 |
|
[BP] GO:0060134 |
None
|
DRD1, DRD2, DRD3 |
2.7365 |
|
[BP] GO:0060158 |
None
|
DRD1, DRD2, DRD5 |
2.7365 |
|
[BP] GO:0009895 |
negative regulation of catabolic process
|
ADORA1, BCL2, EGFR, HCAR2, MCL1, MET, PPARA, SMAD3 |
2.73642 |
|
[BP] GO:0014075 |
None
|
DRD1, DRD2, DRD3, DRD5 |
2.72715 |
|
[BP] GO:0006082 |
organic acid metabolic process
|
ALOX5, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, FABP3, GBA2, GLO1, PIM1, PPARA, PTGES, TBXAS1, TYR |
2.72715 |
|
[BP] GO:0048869 |
cellular developmental process
|
ACHE, ALPL, AXL, BCL2, CDC25B, CDK6, CYP1A1, DRD1, DRD2, EGFR, ESR1, ESRRB, FABP4, FLT3, FUT7, GBA2, GLO1, KDR, MCL1, MET, MMP2, MMP9, RORC, SMAD3, SRC, TEK, TOP2A |
2.72698 |
|
[BP] GO:0080090 |
regulation of primary metabolic process
|
ADORA1, ADORA3, APEX1, AURKB, BCL2, CA9, CDC25B, CSNK2A1, CYP1A1, CYP1B1, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GLO1, HCAR2, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, MTNR1A, NUAK1, PIM1, PPARA, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, XDH |
2.71501 |
|
[BP] GO:0031324 |
negative regulation of cellular metabolic process
|
APEX1, AURKB, BCL2, CSNK2A1, CYP2D6, DRD2, DRD3, DUSP3, ESR1, ESR2, ESRRA, FABP4, HSPA1A, IGF1R, MCL1, MET, MMP12, MMP9, PPARA, PTPN1, RORC, SMAD3, SRC, TNKS, TNKS2, TRPV1, XDH |
2.6856 |
|
[BP] GO:0016042 |
lipid catabolic process
|
ADORA1, AKR1B10, CYP19A1, CYP1A2, CYP1B1, FABP3, FABP4, GBA2 |
2.66532 |
|
[BP] GO:0060065 |
uterus development
|
CYP19A1, ESR1, SRC |
2.6479 |
|
[BP] GO:0051580 |
None
|
DRD1, DRD2, DRD3 |
2.6479 |
|
[BP] GO:0042325 |
regulation of phosphorylation
|
ADORA1, BCL2, CDC25B, DRD1, DRD2, DUSP3, EGFR, ESRRB, FABP4, FLT3, IGF1R, INSR, KDR, MMP9, PPARA, PTPN1, SRC, TEK, XDH |
2.61852 |
|
[BP] GO:1904407 |
positive regulation of nitric oxide metabolic process
|
EGFR, INSR, SMAD3, TRPV1 |
2.60906 |
|
[BP] GO:0045429 |
positive regulation of nitric oxide biosynthetic process
|
EGFR, INSR, SMAD3, TRPV1 |
2.60906 |
|
[BP] GO:0008283 |
cell proliferation
|
ACHE, AURKB, BCL2, CYP1A1, EGFR, ESR1, FLT3, MET, PIM1, SRC, TEK, TYR |
2.58572 |
|
[BP] GO:0043434 |
None
|
APEX1, FABP3, HSD11B2, INSR, PPARA, SRC, TEK, TRPV1 |
2.58528 |
|
[BP] GO:0032102 |
negative regulation of response to external stimulus
|
ADORA1, CYP19A1, DRD1, DRD2, DRD3, PPARA, SMAD3, TEK |
2.57565 |
|
[BP] GO:0010557 |
positive regulation of macromolecule biosynthetic process
|
AURKB, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, IGF1R, INSR, KDR, MET, MMP12, PPARA, RORC, SMAD3, SRC, TNKS, TNKS2, TOP2A |
2.55673 |
|
[BP] GO:0002009 |
morphogenesis of an epithelium
|
BCL2, CA2, CA9, EGFR, ESR1, MET, SMAD3, SRC |
2.5484 |
|
[BP] GO:1903727 |
positive regulation of phospholipid metabolic process
|
FABP3, FLT3, SRC, TEK |
2.53749 |
|
[BP] GO:0043271 |
negative regulation of ion transport
|
ADORA1, BCL2, DRD2, DRD3, GPR35, MMP9 |
2.5303 |
|
[BP] GO:0030003 |
cellular cation homeostasis
|
BCL2, CA2, CA7, DRD1, DRD2, DRD3, DRD5, ESR1, GPR35, SMAD3, TRPV1 |
2.48896 |
|
[BP] GO:2000811 |
negative regulation of anoikis
|
BCL2, MCL1, SRC |
2.48896 |
|
[BP] GO:0030540 |
female genitalia development
|
AXL, CYP19A1, ESR1 |
2.48896 |
|
[BP] GO:0032225 |
None
|
DRD1, DRD2, DRD3 |
2.48896 |
|
[BP] GO:0045931 |
positive regulation of mitotic cell cycle
|
APEX1, CDC25B, CYP1A1, DRD3, DUSP3, INSR |
2.48876 |
|
[BP] GO:0019725 |
cellular homeostasis
|
APEX1, BCL2, CA2, CA7, DRD1, DRD2, DRD3, DRD5, ESR1, GPR35, MCL1, SMAD3, TRPV1 |
2.4759 |
|
[BP] GO:0001954 |
positive regulation of cell-matrix adhesion
|
CDK6, KDR, SMAD3, TEK |
2.4759 |
|
[BP] GO:0097366 |
None
|
DRD1, DRD2, DRD3, DRD5 |
2.4759 |
|
[BP] GO:0051054 |
positive regulation of DNA metabolic process
|
AURKB, EGFR, IGF1R, INSR, SRC, TNKS, TNKS2 |
2.4759 |
|
[BP] GO:2000379 |
positive regulation of reactive oxygen species metabolic process
|
EGFR, INSR, SMAD3, TRPV1, XDH |
2.44407 |
|
[BP] GO:0043085 |
positive regulation of catalytic activity
|
ADORA1, AURKB, BCL2, CDC25B, DRD2, DRD5, EGFR, ESR1, F3, FLT3, HSPA1A, INSR, PTPN1, SMAD3, SRC, TEK, TNKS, XDH |
2.4424 |
|
[BP] GO:0006874 |
cellular calcium ion homeostasis
|
BCL2, DRD1, DRD2, DRD3, DRD5, ESR1, GPR35, SMAD3, TRPV1 |
2.44125 |
|
[BP] GO:1904355 |
positive regulation of telomere capping
|
AURKB, TNKS, TNKS2 |
2.4195 |
|
[BP] GO:0006873 |
cellular ion homeostasis
|
BCL2, CA2, CA7, DRD1, DRD2, DRD3, DRD5, ESR1, GPR35, SMAD3, TRPV1 |
2.41117 |
|
[BP] GO:0048545 |
response to steroid hormone
|
ALPL, BCL2, CA2, EGFR, FLT3, HSD11B2, SRC |
2.40774 |
|
[BP] GO:0046110 |
None
|
AOX1, XDH |
2.40774 |
|
[BP] GO:0060160 |
None
|
DRD2, DRD3 |
2.40774 |
|
[BP] GO:0032849 |
positive regulation of cellular pH reduction
|
CA2, CA7 |
2.40774 |
|
[BP] GO:0016137 |
None
|
AKR1B1, AKR1B10, GBA2 |
2.3522 |
|
[BP] GO:0055074 |
calcium ion homeostasis
|
BCL2, DRD1, DRD2, DRD3, DRD5, ESR1, GPR35, SMAD3, TRPV1 |
2.35087 |
|
[BP] GO:0031960 |
response to corticosteroid
|
ALPL, BCL2, EGFR, FLT3, HSD11B2, SRC |
2.33719 |
|
[BP] GO:0003018 |
None
|
ADORA1, DRD1, DRD5, EGFR, SRC, TEK |
2.33719 |
|
[BP] GO:0010906 |
None
|
ESRRB, INSR, PPARA, RORC, SRC |
2.33087 |
|
[BP] GO:0003014 |
None
|
ADORA1, AKR1B1, BCL2, DRD2, HSD11B2 |
2.33087 |
|
[BP] GO:0072503 |
cellular divalent inorganic cation homeostasis
|
BCL2, DRD1, DRD2, DRD3, DRD5, ESR1, GPR35, SMAD3, TRPV1 |
2.31527 |
|
[BP] GO:0060255 |
regulation of macromolecule metabolic process
|
ACHE, ADORA1, ADORA3, APEX1, AURKB, BCL2, CA9, CDC25B, CDK6, CSNK2A1, CYP1A2, CYP1B1, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP4, FLT3, GLO1, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, NUAK1, PIM1, PPARA, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1, TOP2A, TRPV1, XDH |
2.31511 |
|
[BP] GO:0003006 |
developmental process involved in reproduction
|
ALPL, AXL, BCL2, CDC25B, CYP19A1, EGFR, ESR1, ESRRB, HSD17B2, INSR, SRC |
2.30563 |
|
[BP] GO:2001242 |
regulation of intrinsic apoptotic signaling pathway
|
BCL2, HSPA1A, MCL1, MMP9, PTPN1, SRC |
2.2987 |
|
[BP] GO:0045187 |
None
|
ADORA1, DRD2, DRD3 |
2.29422 |
|
[BP] GO:0051900 |
regulation of mitochondrial depolarization
|
BCL2, KDR, SRC |
2.29422 |
|
[BP] GO:0007617 |
None
|
DRD1, DRD5, MTNR1A |
2.29422 |
|
[BP] GO:0006367 |
transcription initiation from RNA polymerase II promoter
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC |
2.27352 |
|
[BP] GO:0043065 |
positive regulation of apoptotic process
|
BCL2, CYP1B1, F3, HCAR2, MCL1, MMP9, SMAD3, SRC, TOP2A, TRPV1, XDH |
2.26473 |
|
[BP] GO:1903428 |
positive regulation of reactive oxygen species biosynthetic process
|
EGFR, INSR, SMAD3, TRPV1 |
2.26473 |
|
[BP] GO:0010676 |
None
|
ESRRB, INSR, PPARA, SRC |
2.26473 |
|
[BP] GO:0043408 |
regulation of MAPK cascade
|
ADORA1, DRD2, DUSP3, EGFR, FLT3, IGF1R, INSR, KDR, PTPN1, SRC, TEK, XDH |
2.26342 |
|
[BP] GO:0022900 |
electron transport chain
|
AKR1B1, AOX1, CYP19A1, CYP1A2, NQO2, XDH |
2.25115 |
|
[BP] GO:0051828 |
entry into other organism involved in symbiotic interaction
|
AXL, EGFR, HSPA1A, MET, SRC |
2.2483 |
|
[BP] GO:0030260 |
entry into host cell
|
AXL, EGFR, HSPA1A, MET, SRC |
2.2483 |
|
[BP] GO:0051806 |
entry into cell of other organism involved in symbiotic interaction
|
AXL, EGFR, HSPA1A, MET, SRC |
2.2483 |
|
[BP] GO:0044409 |
entry into host
|
AXL, EGFR, HSPA1A, MET, SRC |
2.2483 |
|
[BP] GO:0032210 |
regulation of telomere maintenance via telomerase
|
AURKB, SRC, TNKS, TNKS2 |
2.24338 |
|
[BP] GO:0048148 |
None
|
DRD1, DRD2, DRD3 |
2.24338 |
|
[BP] GO:0035813 |
None
|
ADORA1, DRD2, DRD3 |
2.24338 |
|
[BP] GO:0043068 |
positive regulation of programmed cell death
|
BCL2, CYP1B1, F3, HCAR2, MCL1, MMP9, SMAD3, SRC, TOP2A, TRPV1, XDH |
2.24127 |
|
[BP] GO:0043410 |
positive regulation of MAPK cascade
|
ADORA1, DRD2, EGFR, FLT3, INSR, KDR, PTPN1, SRC, TEK, XDH |
2.23004 |
|
[BP] GO:0018105 |
peptidyl-serine phosphorylation
|
AURKB, BCL2, DRD1, SRC, TNKS, TOP1 |
2.22287 |
|
[BP] GO:0001101 |
response to acid chemical
|
AKR1B1, EGFR, FABP3, HSD17B2, KDR, MMP2, PTGES, SRC |
2.2218 |
|
[BP] GO:0051893 |
regulation of focal adhesion assembly
|
KDR, SMAD3, SRC, TEK |
2.2218 |
|
[BP] GO:0090109 |
regulation of cell-substrate junction assembly
|
KDR, SMAD3, SRC, TEK |
2.2218 |
|
[BP] GO:0051171 |
regulation of nitrogen compound metabolic process
|
ADORA1, ADORA3, APEX1, AURKB, BCL2, CA9, CDC25B, CSNK2A1, CYP1B1, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, GLO1, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MMP9, MTNR1A, NUAK1, PIM1, PPARA, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TRPV1, XDH |
2.22145 |
|
[BP] GO:0042749 |
None
|
ADORA1, DRD2, DRD3 |
2.19051 |
|
[BP] GO:0048732 |
gland development
|
BCL2, CSNK2A1, CYP19A1, EGFR, INSR, SMAD3, TYR |
2.19051 |
|
[BP] GO:0019538 |
protein metabolic process
|
ACHE, ALPL, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, DUSP3, EGFR, ESR1, F10, F3, FLT3, FUT7, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIM1, PPARA, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1, TOP2A |
2.17189 |
|
[BP] GO:0044236 |
multicellular organism metabolic process
|
MMP1, MMP12, MMP2, MMP9, TRPV1 |
2.17019 |
|
[BP] GO:0070213 |
None
|
TNKS, TNKS2 |
2.1663 |
|
[BP] GO:0006145 |
None
|
AOX1, XDH |
2.1663 |
|
[BP] GO:0018894 |
dibenzo-p-dioxin metabolic process
|
CYP1A1, CYP1A2 |
2.1663 |
|
[BP] GO:0050678 |
None
|
CDK6, EGFR, F3, KDR, MMP12, SMAD3, TEK, XDH |
2.1636 |
|
[BP] GO:0001932 |
regulation of protein phosphorylation
|
ADORA1, BCL2, CDC25B, DRD1, DRD2, DUSP3, EGFR, FABP4, FLT3, IGF1R, INSR, KDR, MMP9, PTPN1, SRC, TEK, XDH |
2.14803 |
|
[BP] GO:1903391 |
regulation of adherens junction organization
|
KDR, SMAD3, SRC, TEK |
2.14803 |
|
[BP] GO:0045428 |
regulation of nitric oxide biosynthetic process
|
EGFR, INSR, SMAD3, TRPV1 |
2.14803 |
|
[BP] GO:0030520 |
intracellular estrogen receptor signaling pathway
|
ESR1, ESR2, SRC |
2.14452 |
|
[BP] GO:0042327 |
positive regulation of phosphorylation
|
ADORA1, BCL2, CDC25B, DRD2, EGFR, ESRRB, FLT3, INSR, KDR, MMP9, PTPN1, SRC, TEK, XDH |
2.13271 |
|
[BP] GO:0035556 |
intracellular signal transduction
|
AKR1B1, AXL, BCL2, CYP1B1, DRD1, DRD2, DRD3, DRD5, EGFR, IGF1R, INSR, KDR, MCL1, MET, NUAK1, PTPN1, SRC, TEK |
2.12097 |
|
[BP] GO:0065007 |
biological regulation
|
ACHE, ADORA1, ADORA3, AKR1B1, APEX1, AURKB, AXL, BCL2, CA1, CA12, CA2, CA7, CA9, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, GLO1, GPR35, HCAR2, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, IGF1R, INSR, KDR, MAOA, MCL1, MET, MMP1, MMP12, MMP2, MMP9, MTNR1A, MTNR1B, NUAK1, PIM1, PPARA, PTGES, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1, TOP2A, TRPV1, XDH |
2.12025 |
|
[BP] GO:0009991 |
response to extracellular stimulus
|
ALPL, AXL, BCL2, CYP1A1, EGFR, HSD11B2, SRC, TRPV1, TYR |
2.10487 |
|
[BP] GO:0034502 |
protein localization to chromosome
|
AURKB, ESR1, TNKS, TNKS2 |
2.09836 |
|
[BP] GO:0051966 |
regulation of synaptic transmission, glutamatergic
|
ADORA1, DRD1, DRD2, EGFR |
2.09836 |
|
[BP] GO:0070988 |
demethylation
|
APEX1, CYP1A1, CYP1A2, CYP2D6 |
2.09836 |
|
[BP] GO:2000209 |
regulation of anoikis
|
BCL2, MCL1, SRC |
2.09629 |
|
[BP] GO:0044062 |
None
|
ADORA1, DRD2, DRD3 |
2.09629 |
|
[BP] GO:0009404 |
toxin metabolic process
|
CYP1A1, CYP1A2, CYP1B1 |
2.09629 |
|
[BP] GO:0043405 |
regulation of MAP kinase activity
|
ADORA1, DUSP3, EGFR, FLT3, IGF1R, INSR, PTPN1, SRC |
2.09235 |
|
[BP] GO:0002793 |
None
|
ACHE, ADORA1, DRD2, EGFR, HCAR2, MMP12, SRC |
2.08017 |
|
[BP] GO:1904356 |
regulation of telomere maintenance via telomere lengthening
|
AURKB, SRC, TNKS, TNKS2 |
2.07752 |
|
[BP] GO:0007610 |
None
|
BCL2, DRD1, DRD2, DRD3, DRD5, EGFR, INSR, MTNR1A, PPARA, TRPV1 |
2.07489 |
|
[BP] GO:0070301 |
cellular response to hydrogen peroxide
|
AKR1B1, APEX1, AXL, CYP1B1 |
2.05366 |
|
[BP] GO:0042737 |
drug catabolic process
|
ACHE, CYP1A2, CYP2A6, CYP2D6, MAOA |
2.05366 |
|
[BP] GO:0051894 |
None
|
KDR, SMAD3, TEK |
2.05252 |
|
[BP] GO:1903409 |
reactive oxygen species biosynthetic process
|
CYP1A1, CYP1A2, CYP1B1 |
2.05252 |
|
[BP] GO:0040008 |
regulation of growth
|
BCL2, CSNK2A1, DRD2, DRD3, EGFR, ESR2, HSPA1A, INSR, PIM1, SMAD3, TNKS2 |
2.05252 |
|
[BP] GO:0055082 |
cellular chemical homeostasis
|
BCL2, CA2, CA7, DRD1, DRD2, DRD3, DRD5, ESR1, GPR35, SMAD3, TRPV1 |
2.05252 |
|
[BP] GO:0055065 |
metal ion homeostasis
|
BCL2, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, GPR35, SMAD3, TRPV1 |
2.051 |
|
[BP] GO:1901575 |
None
|
ACHE, ADORA1, AKR1B10, AOX1, AURKB, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A6, CYP2D6, FABP3, FABP4, FUT7, GBA2, HSPA1A, MAOA, XDH |
2.04946 |
|
[BP] GO:1900544 |
None
|
DRD1, DRD5, ESRRB, INSR, MTNR1A |
2.0454 |
|
[BP] GO:0045981 |
None
|
DRD1, DRD5, ESRRB, INSR, MTNR1A |
2.0454 |
|
[BP] GO:0050728 |
negative regulation of inflammatory response
|
ADORA1, CYP19A1, PPARA, SMAD3, TEK |
2.0454 |
|
[BP] GO:0051338 |
regulation of transferase activity
|
ADORA1, AURKB, CDC25B, DRD2, DUSP3, EGFR, FABP4, FLT3, IGF1R, INSR, PTPN1, SRC, TEK, TNKS |
2.04458 |
|
[BP] GO:0002521 |
leukocyte differentiation
|
AXL, BCL2, FLT3, FUT7, GLO1, MMP9, RORC |
2.03504 |
|
[BP] GO:0018209 |
peptidyl-serine modification
|
AURKB, BCL2, DRD1, SRC, TNKS, TOP1 |
2.01958 |
|
[BP] GO:0010942 |
positive regulation of cell death
|
BCL2, CYP1B1, F3, HCAR2, MCL1, MMP9, SMAD3, SRC, TOP2A, TRPV1, XDH |
2.01612 |
|
[BP] GO:0008610 |
lipid biosynthetic process
|
ACHE, AKR1B1, CSNK2A1, CYP19A1, CYP1A1, HSD11B1, HSD11B2, HSD17B1, HSD17B2, PTGES |
2.01309 |
|
[BP] GO:0050927 |
None
|
F3, KDR, SMAD3 |
2.01309 |
|
[BP] GO:0050886 |
None
|
DRD3, DRD5, HSD11B2 |
2.01309 |
|
[BP] GO:0001990 |
None
|
DRD3, DRD5, HSD11B2 |
2.01309 |
|
[BP] GO:0006464 |
cellular protein modification process
|
ALPL, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, DUSP3, EGFR, ESR1, F10, FLT3, FUT7, IGF1R, INSR, KDR, MET, NUAK1, PIM1, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1, TOP2A |
2.0124 |
|
[BP] GO:0036211 |
protein modification process
|
ALPL, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, DUSP3, EGFR, ESR1, F10, FLT3, FUT7, IGF1R, INSR, KDR, MET, NUAK1, PIM1, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1, TOP2A |
2.0124 |
|
[BP] GO:0030336 |
None
|
ADORA1, ADORA3, APEX1, BCL2, CYP19A1, CYP1B1, DRD2 |
2.0119 |
|
[BP] GO:0045934 |
None
|
APEX1, AURKB, DRD2, DRD3, ESR1, ESR2, ESRRA, FABP4, HSPA1A, MMP12, PPARA, RORC, SMAD3, SRC, TNKS, TNKS2, TRPV1 |
2.0119 |
|
[BP] GO:0044267 |
cellular protein metabolic process
|
ALPL, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, DRD1, DUSP3, EGFR, ESR1, F10, FLT3, FUT7, IGF1R, INSR, KDR, MET, MMP1, MMP2, NUAK1, PIM1, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1, TOP2A |
2.0119 |
|
[BP] GO:0006807 |
nitrogen compound metabolic process
|
ACHE, AKR1B1, AKR1B10, ALPL, AOX1, APEX1, AURKB, AXL, BCL2, CDC25B, CDK6, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FLT3, FUT7, GBA2, GLO1, HSPA1A, IGF1R, INSR, KDR, MAOA, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIM1, PPARA, PTPN1, RORC, SMAD3, SRC, TEK, TNKS, TNKS2, TOP1, TOP2A, TYR, XDH |
2.0119 |
|
[BP] GO:0002791 |
None
|
ACHE, ADORA1, DRD2, DRD3, EGFR, HCAR2, MMP12, MTNR1B, SRC |
2.0119 |
|
[BP] GO:2000573 |
positive regulation of DNA biosynthetic process
|
AURKB, SRC, TNKS, TNKS2 |
2.0119 |
|
[BP] GO:0021853 |
None
|
DRD1, DRD2 |
2.0119 |
|
[BP] GO:0043696 |
None
|
CDK6, ESRRB |
2.0119 |
|
[BP] GO:0043697 |
None
|
CDK6, ESRRB |
2.0119 |
|
[BP] GO:0010641 |
None
|
F3, SRC |
2.0119 |
|
[BP] GO:0090325 |
None
|
DRD2, DRD3 |
2.0119 |
|
[BP] GO:0007598 |
None
|
F10, F3 |
2.0119 |
|
[BP] GO:1904936 |
None
|
DRD1, DRD2 |
2.0119 |
|
[BP] GO:0042321 |
None
|
ADORA1, DRD2 |
2.0119 |
|
[BP] GO:0048729 |
tissue morphogenesis
|
BCL2, CA2, CA9, EGFR, ESR1, MET, SMAD3, SRC |
2.0119 |
|
[BP] GO:0030802 |
None
|
DRD1, DRD2, DRD3, DRD5, MTNR1A |
2.00781 |
|
[BP] GO:0008150 |
biological_process
|
ACHE, ADORA1, ADORA3, AKR1B1, AKR1B10, ALOX5, ALPL, AOX1, APEX1, AURKB, AXL, BCL2, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, GPR35, HCAR2, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, IGF1R, INSR, KDR, MAOA, MCL1, MET, MMP1, MMP12, MMP2, MMP9, MTNR1A, MTNR1B, NQO2, NUAK1, PIM1, PPARA, PTGES, PTPN1, RORC, SMAD3, SRC, TBXAS1, TEK, TNKS, TNKS2, TOP1, TOP2A, TRPV1, TYR, XDH |
2.00781 |
|
[BP] GO:0051128 |
regulation of cellular component organization
|
AURKB, AXL, BCL2, CSNK2A1, DRD2, DRD3, EGFR, ESR1, ESR2, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP9, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
2.0019 |
|
[BP] GO:0010810 |
regulation of cell-substrate adhesion
|
BCL2, CDK6, KDR, SMAD3, SRC, TEK |
2.00102 |
|
[CC] GO:0016020 |
membrane
|
ACHE, ADORA1, ADORA3, ALOX5, ALPL, AXL, BCL2, CA12, CA14, CA2, CA4, CA9, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, F10, F3, FLT3, FUT7, GBA2, GLO1, GPR35, HCAR2, HSD11B1, HSD11B2, HSD17B2, IGF1R, INSR, KDR, MAOA, MCL1, MET, MMP2, MTNR1A, MTNR1B, PIM1, PTGES, PTPN1, SMAD3, SRC, TBXAS1, TEK, TNKS, TNKS2, TRPV1, TYR |
3.53969 |
|
[CC] GO:0005789 |
endoplasmic reticulum membrane
|
BCL2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD1, EGFR, GBA2, HSD11B1, HSD11B2, HSD17B2, PTGES, TBXAS1 |
3.47332 |
|
[CC] GO:0044432 |
endoplasmic reticulum part
|
BCL2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD1, EGFR, F10, FLT3, GBA2, HSD11B1, HSD11B2, HSD17B2, PTGES, PTPN1, TBXAS1 |
3.39101 |
|
[CC] GO:0044444 |
cytoplasmic part
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, AOX1, APEX1, AURKB, BCL2, CA1, CA2, CA4, CA5A, CA5B, CA7, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, F10, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, INSR, KDR, MAOA, MCL1, MMP2, MMP9, NQO2, PIM1, PTGES, PTPN1, SMAD3, SRC, TBXAS1, TNKS, TNKS2, TOP1, TOP2A, TRPV1, TYR, XDH |
3.36337 |
|
[CC] GO:0031226 |
intrinsic component of plasma membrane
|
ADORA1, ADORA3, AXL, CA4, DRD1, DRD2, DRD3, DRD5, F10, F3, FLT3, GPR35, IGF1R, INSR, KDR, MET, MTNR1A, MTNR1B, TEK, TRPV1 |
3.20352 |
|
[CC] GO:0031253 |
None
|
ADORA1, CA4, CA9, DRD1, DRD2, DRD5, INSR, SRC, TRPV1 |
2.97404 |
|
[CC] GO:0044425 |
membrane part
|
ACHE, ADORA1, ADORA3, ALPL, AXL, BCL2, CA12, CA14, CA2, CA4, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, F10, F3, FLT3, FUT7, GBA2, GPR35, HCAR2, HSD11B1, HSD11B2, HSD17B2, IGF1R, INSR, KDR, MAOA, MCL1, MET, MTNR1A, MTNR1B, PTGES, PTPN1, SRC, TBXAS1, TEK, TRPV1, TYR |
2.96071 |
|
[CC] GO:0009330 |
None
|
TOP1, TOP2A |
2.80075 |
|
[CC] GO:0005886 |
plasma membrane
|
ACHE, ADORA1, ADORA3, ALPL, AXL, CA12, CA14, CA2, CA4, CA9, CSNK2A1, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, F10, F3, FLT3, GBA2, GLO1, GPR35, HCAR2, IGF1R, INSR, KDR, MET, MMP2, MTNR1A, MTNR1B, PIM1, PTPN1, SMAD3, SRC, TEK, TRPV1 |
2.4759 |
|
[CC] GO:0031233 |
None
|
CA4, F10, F3 |
2.24338 |
|
[CC] GO:0043227 |
membrane-bounded organelle
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALPL, AOX1, APEX1, AURKB, AXL, BCL2, CA1, CA2, CA4, CA5A, CA5B, CA6, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, HSPA1A, IGF1R, INSR, KDR, MAOA, MCL1, MMP12, MMP2, MMP9, NQO2, NUAK1, PIM1, PPARA, PTPN1, RORC, SMAD3, SRC, TNKS, TNKS2, TOP1, TOP2A, TYR, XDH |
2.08944 |
|
[CC] GO:0005887 |
integral component of plasma membrane
|
ADORA1, ADORA3, AXL, DRD1, DRD2, DRD3, DRD5, FLT3, GPR35, IGF1R, INSR, KDR, MET, MTNR1A, MTNR1B, TEK, TRPV1 |
2.07014 |
|
[CC] GO:0016323 |
basolateral plasma membrane
|
ADORA1, CA2, CA4, CA9, EGFR, TEK |
2.0119 |
|
[MF] GO:0046914 |
transition metal ion binding
|
ALOX5, AOX1, CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, ESR1, ESR2, ESRRA, ESRRB, GLO1, MMP1, MMP12, MMP2, MMP9, NQO2, PIM1, PPARA, PTPN1, RORC, SMAD3, TBXAS1, TNKS, TYR, XDH |
18.8599 |
|
[MF] GO:0004089 |
carbonate dehydratase activity
|
CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9 |
16.1897 |
|
[MF] GO:0043167 |
ion binding
|
ACHE, ALOX5, ALPL, AOX1, APEX1, AURKB, AXL, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, GLO1, HSD17B1, HSPA1A, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NQO2, NUAK1, PIM1, PPARA, PTGES, PTPN1, RORC, SMAD3, SRC, TBXAS1, TEK, TNKS, TNKS2, TOP1, TOP2A, TRPV1, TYR, XDH |
15.2231 |
|
[MF] GO:0003824 |
catalytic activity
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, ALPL, AOX1, APEX1, AURKB, AXL, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DUSP3, EGFR, F10, F3, FLT3, FUT7, GBA2, GLO1, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, IGF1R, INSR, KDR, MAOA, MET, MMP1, MMP12, MMP2, MMP9, NQO2, NUAK1, PIM1, PTGES, PTPN1, SRC, TBXAS1, TEK, TNKS, TNKS2, TOP1, TOP2A, TYR, XDH |
13.5989 |
|
[MF] GO:0016835 |
carbon-oxygen lyase activity
|
APEX1, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9 |
10.2472 |
|
[MF] GO:0016836 |
hydro-lyase activity
|
CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9 |
10.1673 |
|
[MF] GO:0008270 |
zinc ion binding
|
CA1, CA12, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, ESR1, ESR2, ESRRA, ESRRB, GLO1, MMP1, MMP12, MMP2, MMP9, NQO2, PPARA, PTPN1, RORC, SMAD3, TNKS |
9.91631 |
|
[MF] GO:0043169 |
cation binding
|
ACHE, ALOX5, ALPL, AOX1, APEX1, AURKB, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD1, DRD2, DRD3, DRD5, ESR1, ESR2, ESRRA, ESRRB, F10, GLO1, MMP1, MMP12, MMP2, MMP9, NQO2, NUAK1, PIM1, PPARA, PTPN1, RORC, SMAD3, TBXAS1, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
9.89952 |
|
[MF] GO:0008144 |
drug binding
|
ACHE, AURKB, AXL, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2D6, DRD1, DRD2, DRD3, DRD5, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, NQO2, NUAK1, PIM1, PPARA, SRC, TEK, TOP1, TOP2A, TRPV1 |
8.28401 |
|
[MF] GO:0016491 |
oxidoreductase activity
|
AKR1B1, AKR1B10, ALOX5, AOX1, APEX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, HSD11B1, HSD11B2, HSD17B1, HSD17B2, MAOA, NQO2, TBXAS1, TYR, XDH |
8.23205 |
|
[MF] GO:0016712 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6 |
7.86817 |
|
[MF] GO:0016829 |
lyase activity
|
APEX1, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, GLO1 |
7.58435 |
|
[MF] GO:0046872 |
metal ion binding
|
ALOX5, ALPL, AOX1, APEX1, AURKB, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, ESR1, ESR2, ESRRA, ESRRB, F10, GLO1, MMP1, MMP12, MMP2, MMP9, NQO2, NUAK1, PIM1, PPARA, PTPN1, RORC, SMAD3, TBXAS1, TNKS, TNKS2, TOP2A, TRPV1, TYR, XDH |
7.24073 |
|
[MF] GO:0005506 |
iron ion binding
|
ALOX5, AOX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, TBXAS1, XDH |
7.09139 |
|
[MF] GO:0038023 |
signaling receptor activity
|
ADORA1, ADORA3, AXL, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, HCAR2, IGF1R, INSR, KDR, MET, MTNR1A, MTNR1B, PPARA, RORC, TEK, TRPV1 |
7.02545 |
|
[MF] GO:0004714 |
transmembrane receptor protein tyrosine kinase activity
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, TEK |
6.8142 |
|
[MF] GO:0004497 |
monooxygenase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, TBXAS1, TYR |
6.72972 |
|
[MF] GO:0070330 |
aromatase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2D6 |
6.57946 |
|
[MF] GO:0060089 |
molecular transducer activity
|
ADORA1, ADORA3, AXL, CDK6, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, HCAR2, IGF1R, INSR, KDR, MET, MTNR1A, MTNR1B, PPARA, RORC, TEK, TRPV1 |
6.4472 |
|
[MF] GO:0004872 |
receptor activity
|
ADORA1, ADORA3, AXL, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, HCAR2, IGF1R, INSR, KDR, MET, MTNR1A, MTNR1B, PPARA, RORC, TEK, TRPV1 |
6.08663 |
|
[MF] GO:0019199 |
transmembrane receptor protein kinase activity
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, TEK |
6.08538 |
|
[MF] GO:0048037 |
cofactor binding
|
AOX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, HSD11B2, HSD17B1, NQO2, PTGES, SRC, TBXAS1, XDH |
5.9333 |
|
[MF] GO:0004871 |
signal transducer activity
|
ADORA1, ADORA3, AXL, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESR2, ESRRA, ESRRB, F3, FLT3, GPR35, HCAR2, IGF1R, INSR, KDR, MET, MTNR1A, MTNR1B, PPARA, RORC, SMAD3, TEK, TRPV1 |
5.92011 |
|
[MF] GO:0020037 |
heme binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, SRC, TBXAS1 |
5.74208 |
|
[MF] GO:0046906 |
tetrapyrrole binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, SRC, TBXAS1 |
5.51991 |
|
[MF] GO:0016705 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, TBXAS1, TYR |
5.15817 |
|
[MF] GO:0019825 |
oxygen binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2D6 |
5.0041 |
|
[MF] GO:0098531 |
transcription factor activity, direct ligand regulated sequence-specific DNA binding
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC |
4.80945 |
|
[MF] GO:0004879 |
nuclear receptor activity
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC |
4.80945 |
|
[MF] GO:0042562 |
hormone binding
|
ACHE, EGFR, HSD17B1, IGF1R, INSR, MTNR1A, NQO2 |
4.70863 |
|
[MF] GO:0005496 |
steroid binding
|
ESR1, ESR2, ESRRA, ESRRB, HSD11B2, HSD17B1, RORC |
4.68512 |
|
[MF] GO:0004713 |
protein tyrosine kinase activity
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, SRC, TEK |
4.66577 |
|
[MF] GO:0016614 |
oxidoreductase activity, acting on CH-OH group of donors
|
AKR1B1, AKR1B10, AOX1, HSD11B1, HSD11B2, HSD17B1, HSD17B2, XDH |
4.53536 |
|
[MF] GO:0004952 |
None
|
DRD1, DRD2, DRD3, DRD5 |
4.53194 |
|
[MF] GO:0004672 |
protein kinase activity
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KDR, MET, NUAK1, PIM1, SRC, TEK, TOP1 |
4.49048 |
|
[MF] GO:0003707 |
steroid hormone receptor activity
|
ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC |
4.41003 |
|
[MF] GO:0035240 |
None
|
DRD1, DRD2, DRD3, DRD5 |
4.40433 |
|
[MF] GO:0008395 |
steroid hydroxylase activity
|
CYP19A1, CYP1A1, CYP2A13, CYP2A6, CYP2D6 |
4.24617 |
|
[MF] GO:0099600 |
transmembrane receptor activity
|
ADORA1, ADORA3, AXL, DRD1, DRD2, DRD3, DRD5, EGFR, F3, FLT3, GPR35, HCAR2, IGF1R, INSR, KDR, MET, MTNR1A, MTNR1B, TEK, TRPV1 |
4.13575 |
|
[MF] GO:0004888 |
transmembrane signaling receptor activity
|
ADORA1, ADORA3, AXL, DRD1, DRD2, DRD3, DRD5, EGFR, F3, FLT3, GPR35, HCAR2, IGF1R, INSR, KDR, MET, MTNR1A, MTNR1B, TEK, TRPV1 |
4.13575 |
|
[MF] GO:0044877 |
macromolecular complex binding
|
ACHE, ADORA1, APEX1, CSNK2A1, EGFR, ESRRB, FLT3, IGF1R, INSR, KDR, MMP12, MMP9, PIM1, PPARA, PTPN1, SMAD3, SRC |
3.70319 |
|
[MF] GO:1901338 |
None
|
DRD1, DRD2, DRD3, DRD5 |
3.68832 |
|
[MF] GO:0008289 |
lipid binding
|
AXL, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, HSD11B2, HSD17B1, PPARA, RORC, TRPV1 |
3.66314 |
|
[MF] GO:0016773 |
phosphotransferase activity, alcohol group as acceptor
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KDR, MET, NUAK1, PIM1, SRC, TEK, TOP1 |
3.629 |
|
[MF] GO:0032403 |
protein complex binding
|
ACHE, ADORA1, APEX1, EGFR, ESRRB, FLT3, IGF1R, INSR, KDR, MMP12, MMP9, PPARA, PTPN1, SMAD3, SRC |
3.57491 |
|
[MF] GO:0016301 |
kinase activity
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KDR, MET, NUAK1, PIM1, SRC, TEK, TOP1 |
3.21434 |
|
[MF] GO:0033764 |
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
|
HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
3.21037 |
|
[MF] GO:0004716 |
signal transducer, downstream of receptor, with protein tyrosine kinase activity
|
EGFR, INSR, KDR |
3.16036 |
|
[MF] GO:0097159 |
organic cyclic compound binding
|
ADORA1, AOX1, APEX1, AURKB, AXL, BCL2, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD1, DRD2, DRD3, DRD5, EGFR, ESR1, ESR2, ESRRA, ESRRB, FLT3, HSD11B2, HSD17B1, HSPA1A, IGF1R, INSR, KDR, MET, MMP12, MTNR1A, NQO2, NUAK1, PIM1, PPARA, PTPN1, RORC, SMAD3, SRC, TBXAS1, TEK, TOP1, TOP2A, TRPV1, XDH |
3.14564 |
|
[MF] GO:0016229 |
steroid dehydrogenase activity
|
HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
3.10502 |
|
[MF] GO:0009055 |
electron transfer activity
|
AKR1B1, AOX1, CYP19A1, CYP1A2, NQO2, XDH |
3.07064 |
|
[MF] GO:0016616 |
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
|
AKR1B1, AKR1B10, HSD11B1, HSD11B2, HSD17B1, HSD17B2 |
2.87266 |
|
[MF] GO:0070405 |
ammonium ion binding
|
ACHE, DRD1, DRD2, DRD3, DRD5 |
2.80377 |
|
[MF] GO:0038052 |
RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
|
ESR1, ESR2 |
2.80075 |
|
[MF] GO:0003845 |
None
|
HSD11B1, HSD11B2 |
2.80075 |
|
[MF] GO:0008389 |
None
|
CYP2A13, CYP2A6 |
2.80075 |
|
[MF] GO:0036094 |
small molecule binding
|
ADORA1, AOX1, AURKB, AXL, CDK6, CSNK2A1, EGFR, FABP3, FABP4, FLT3, HSD11B2, HSD17B1, HSPA1A, IGF1R, INSR, KDR, MET, NQO2, NUAK1, PIM1, SRC, TEK, TOP1, TOP2A, TRPV1, XDH |
2.73813 |
|
[MF] GO:0042802 |
identical protein binding
|
ACHE, AOX1, BCL2, CSNK2A1, DRD2, EGFR, ESR1, ESR2, FLT3, IGF1R, KDR, MCL1, MET, MMP9, NQO2, SMAD3, TOP2A, TRPV1, TYR, XDH |
2.67421 |
|
[MF] GO:0000166 |
nucleotide binding
|
AOX1, AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, HSD11B2, HSD17B1, HSPA1A, IGF1R, INSR, KDR, MET, NQO2, NUAK1, PIM1, SRC, TEK, TOP1, TOP2A, TRPV1, XDH |
2.55502 |
|
[MF] GO:1901265 |
nucleoside phosphate binding
|
AOX1, AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, HSD11B2, HSD17B1, HSPA1A, IGF1R, INSR, KDR, MET, NQO2, NUAK1, PIM1, SRC, TEK, TOP1, TOP2A, TRPV1, XDH |
2.55317 |
|
[MF] GO:0016772 |
transferase activity, transferring phosphorus-containing groups
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KDR, MET, NUAK1, PIM1, SRC, TEK, TOP1 |
2.52341 |
|
[MF] GO:0016903 |
None
|
AKR1B1, AKR1B10, AOX1, XDH |
2.50176 |
|
[MF] GO:0008502 |
None
|
MTNR1A, MTNR1B |
2.40774 |
|
[MF] GO:0043168 |
anion binding
|
AOX1, AURKB, AXL, CDK6, CSNK2A1, EGFR, F10, F3, FABP3, FABP4, FLT3, HSD17B1, HSPA1A, IGF1R, INSR, KDR, MET, NQO2, NUAK1, PIM1, PTGES, SRC, TEK, TOP1, TOP2A, TRPV1, XDH |
2.36115 |
|
[MF] GO:0005524 |
ATP binding
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIM1, SRC, TEK, TOP1, TOP2A, TRPV1 |
2.27222 |
|
[MF] GO:0140096 |
catalytic activity, acting on a protein
|
AURKB, AXL, CDC25B, CDK6, CSNK2A1, DUSP3, EGFR, F10, F3, FLT3, IGF1R, INSR, KDR, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIM1, PTPN1, SRC, TEK, TOP1 |
2.24107 |
|
[MF] GO:0019902 |
phosphatase binding
|
BCL2, EGFR, MET, PPARA, PTPN1, SMAD3 |
2.23504 |
|
[MF] GO:0032559 |
adenyl ribonucleotide binding
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIM1, SRC, TEK, TOP1, TOP2A, TRPV1 |
2.17251 |
|
[MF] GO:0001588 |
None
|
DRD1, DRD5 |
2.1663 |
|
[MF] GO:0034056 |
estrogen response element binding
|
ESR1, ESR2 |
2.1663 |
|
[MF] GO:0030554 |
adenyl nucleotide binding
|
AURKB, AXL, CDK6, CSNK2A1, EGFR, FLT3, HSPA1A, IGF1R, INSR, KDR, MET, NUAK1, PIM1, SRC, TEK, TOP1, TOP2A, TRPV1 |
2.14803 |
|
[MF] GO:0005518 |
collagen binding
|
ACHE, MMP12, MMP9, SMAD3 |
2.01409 |
|
[MF] GO:0030284 |
estrogen receptor activity
|
ESR1, ESR2 |
2.0119 |
|
[MF] GO:0043559 |
insulin binding
|
IGF1R, INSR |
2.0119 |
|
[MF] GO:0051434 |
BH3 domain binding
|
BCL2, MCL1 |
2.0119 |
|
[MF] GO:0003674 |
molecular_function
|
ACHE, ADORA1, ADORA3, AKR1B1, AKR1B10, ALOX5, ALPL, AOX1, APEX1, AURKB, AXL, BCL2, CA1, CA12, CA14, CA2, CA4, CA5A, CA5B, CA6, CA7, CA9, CDC25B, CDK6, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6, DRD1, DRD2, DRD3, DRD5, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F3, FABP3, FABP4, FLT3, FUT7, GBA2, GLO1, GPR35, HCAR2, HSD11B1, HSD11B2, HSD17B1, HSD17B2, HSPA1A, IGF1R, INSR, KDR, MAOA, MCL1, MET, MMP1, MMP12, MMP2, MMP9, MTNR1A, MTNR1B, NQO2, NUAK1, PIM1, PPARA, PTGES, PTPN1, RORC, SMAD3, SRC, TBXAS1, TEK, TNKS, TNKS2, TOP1, TOP2A, TRPV1, TYR, XDH |
2.00234 |
