Prescription Description
| Prescription ID | TCMF3537 |
| Pinyin Name | Gu Yan Ling Pian |
| Chinese Name | 骨炎灵片 |
| English Name | Gu Yan Ling Tablets |
| Function Description | 疮疡 |
| Indications | None |
| Disease ICD-11 Category | |
| Human Tissues Associated with Indication | Skin |
| Reference | CFDA |
| Reference Book/link | http://samr.cfda.gov.cn/WS01/CL0001/ |
Prescription Components
| Component ID | Latin Name | Chinese Name | Component Quantity | Barcode |
|---|---|---|---|---|
| TCMH421 | Angelica sinensis | 当归 | TCMH421 | ITSAF173-14 |
| TCMH981 | Astragalus membranaceus | 黄芪 | TCMH981 | ITSAK2981-14 |
| TCMH451 | Rehmannia glutinosa | 地黄 | TCMH451 | ITSAH4578-14 |
| TCMH305 | Cnidium officinale | 川芎 | TCMH305 | ITSAP4207-14 |
| TCMH2149 | Cuscuta australis | 菟丝子 | TCMH2149 | ITSAP4209-14 |
| TCMH1186 | Lycium chinense | 枸杞子 | TCMH1186 | ITSAO4545-14 |
| TCMH2343 | Scrophularia ningpoensis | 玄参 | TCMH2343 | ITSAO4295-14 |
| TCMH628 | Glycyrrhiza uralensis | 甘草 | TCMH628 | ITSAM892-14 |
| TCMH118 | Angelica dahurica | 白芷 | TCMH118 | ITSAK3312-14 |
| TCMH700 | Drynaria fortunei | 骨碎补 | TCMH700 | GBVM3977-11 |
| TCMH2376 | Corydalis yanhusuo | 延胡索 | TCMH2376 | |
| TCMH284 | Melia toosendan | 川楝子 | TCMH284 | KY197925 |
| TCMH1632 | Taraxacum mongolicum | 蒲公英 | TCMH1632 | ITSAG679-14 |
| TCMH2711 | Viola yedoensis | 紫花地丁 | TCMH2711 |
Targeted Human Proteins by the Ingredients of Prescription
| Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
|---|---|---|---|---|
| TCMT100 | TTR | Transthyretin | Unclassified | P02766 |
| TCMT101 | PTPN1 | Protein-tyrosine phosphatase 1B | Hydrolase | P18031 |
| TCMT112 | ADORA3 | Adenosine A3 receptor | GPCR | P0DMS8 |
| TCMT126 | TERT | Telomerase reverse transcriptase | Transferase | O14746 |
| TCMT127 | PARP1 | Poly [ADP-ribose] polymerase-1 | Transferase | P09874 |
| TCMT128 | TNKS2 | Tankyrase-2 | Transferase | Q9H2K2 |
| TCMT129 | TNKS | Tankyrase-1 | Transferase | O95271 |
| TCMT13 | APEX1 | DNA-(apurinic or apyrimidinic site) lyase | Lyase | P27695 |
| TCMT130 | ALOX5 | Arachidonate 5-lipoxygenase | Oxidoreductase | P09917 |
| TCMT131 | ACHE | Acetylcholinesterase | Hydrolase | P22303 |
Showing 1 to 10 of 121 entries
Targeted Pathogenic Microbes by the Ingredients of Prescription
| Target ID | Target Name |
|---|---|
| TCMT1170 | Enterobacter cloacae |
| TCMT1175 | Human immunodeficiency virus |
| TCMT1176 | Streptococcus pneumoniae |
| TCMT1178 | Actinomyces viscosus |
| TCMT1179 | Escherichia coli ATCC 8739 |
| TCMT1181 | Mycobacterium tuberculosis H37Ra |
| TCMT1186 | Plasmodium yoelii yoelii |
| TCMT1189 | Pseudomonas fluorescens |
| TCMT1190 | Plasmodium falciparum (isolate FcB1 / Columbia) |
| TCMT1191 | Bacillus megaterium |
Showing 1 to 10 of 80 entries
Gene Ontology Associated to Targeted Human Proteins
| GO Term | GO Name | Enriched Genes | Log10 Adjusted P-value |
|---|---|---|---|
| [BP] GO:0000302 | response to reactive oxygen species | AKR1B1, APEX1, AXL, BCL2, CYP1B1, MMP9, SRC | 3.03788 |
| [BP] GO:0001505 | regulation of neurotransmitter levels | ACHE, CYP1B1, DRD1, DRD2, DRD3, GPER1, HTR1A | 2.16491 |
| [BP] GO:0001659 | None | ADORA1, DRD1, DRD2, HTR2A | 3.09188 |
| [BP] GO:0001666 | response to hypoxia | ADORA1, BCL2, CYP1A1, DRD2, HSD11B2, MMP2, PPARA, SRC, TERT | 3.66295 |
| [BP] GO:0001676 | long-chain fatty acid metabolic process | CBR1, CYP1A1, CYP1A2, CYP1B1, CYP2A13, CYP2A6, CYP2D6 | 4.3819 |
| [BP] GO:0001932 | regulation of protein phosphorylation | ADORA1, ADRA1A, APP, AR, BCL2, CDC25B, DRD1, DRD2, FABP4, FLT3, GPER1, HTR2A, HTR2B, IGF1R, KDR, MMP9, PTPN1, SRC, XDH | 3.22836 |
| [BP] GO:0001934 | positive regulation of protein phosphorylation | ADORA1, ADRA1A, APP, AR, BCL2, CDC25B, DRD2, FLT3, GPER1, HTR2A, HTR2B, KDR, MMP9, PTPN1, SRC, XDH | 3.4922 |
| [BP] GO:0001963 | None | DRD1, DRD2, DRD3 | 2.63317 |
| [BP] GO:0001975 | None | DRD1, DRD2, DRD3 | 2.03123 |
| [BP] GO:0002031 | None | DRD2, DRD3, HTR2B | 2.99386 |
Showing 1 to 10 of 473 entries
KEGG Pathways Associated to Targeted Human Proteins
| KEGG Pathway ID | Enriched Genes | Log10 Adjusted P-value |
|---|---|---|
| Acute myeloid leukemia_Homo sapiens_hsa05221 | FLT3, PIM1 | 1.126 |
| Adherens junction_Homo sapiens_hsa04520 | PTPN1, CSNK2A1, SRC, MET, IGF1R | 3.7934 |
| Adipocytokine signaling pathway_Homo sapiens_hsa04920 | PPARA | 0.4742 |
| Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | BCL2, ADRA1A | 0.6712 |
| AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | MMP2, BCL2, PIM1, F3 | 2.2852 |
| Alcoholism_Homo sapiens_hsa05034 | DRD1, DRD2 | 0.5615 |
| Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | HSD11B2 | 0.6089 |
| Alzheimer's disease_Homo sapiens_hsa05010 | APP | 0.273 |
| Amphetamine addiction_Homo sapiens_hsa05031 | DRD1 | 0.4825 |
| AMPK signaling pathway_Homo sapiens_hsa04152 | ADRA1A, IGF1R | 0.7354 |
Showing 1 to 10 of 143 entries
Target Exprsssion in Healthy Human Tissues (protein & mRNA level)
Protein expression data was from the "Human Proteome Map" datasetmRNA expression data was from the "GTEx" dataset
Average Target Expression (Fold Change) in Multiple Disease Conditions
Fold Change with Corresponding Normal SamplesClick each cell within the heatmap to access gene expression of individual patient samples