Prescription Description
| Prescription ID | TCMF2504 |
| Pinyin Name | Shu Gan Zhu Yun Tang |
| Chinese Name | 疏肝助孕汤 |
| English Name | Liver Soothing and Pregency Assisting Decoction |
| Function Description | |
| Indications | None |
| Disease ICD-11 Category | |
| Human Tissues Associated with Indication | |
| Reference | Chinese Classical Prescriptions |
| Reference Book/link | ISBN 7-5023-3930-2 |
Prescription Components
| Component ID | Latin Name | Chinese Name | Component Quantity | Barcode |
|---|---|---|---|---|
| TCMH228 | Bupleurum chinense | 柴胡 | TCMH228 | ITSAM2218-14 |
| TCMH2532 | Curcuma aromatica | 郁金 | TCMH2532 | ITSAF2298-14 |
| TCMH1695 | Pericarpium citri reticulatae viride | 青皮 | TCMH1695 | |
| TCMH258 | Paeonia obovata | 赤芍 | TCMH258 | GBVX7902-15 |
| TCMH104 | Paeonia lactiflora | 白芍 | TCMH104 | ITSAH2416-14 |
| TCMH942 | Radix achyranthis bidentatae | 怀牛膝 | TCMH942 | |
| TCMH2634 | Rhizoma cyperi preparata | 制香附 | TCMH2634 | |
| TCMH2636 | Rhizoma corydalis | 制玄胡 | TCMH2636 | |
| TCMH2161 | Vaccaria segetalis | 王不留行 | TCMH2161 | |
| TCMH1348 | Liquidambar formosana | 路路通 | TCMH1348 | ITSAM899-14 |
| TCMH421 | Angelica sinensis | 当归 | TCMH421 | ITSAF173-14 |
| TCMH293 | Manis pentadactyla | 穿山甲 | TCMH293 | GBMA15413-17 |
| TCMH1346 | Cornu cervi degelatinatum | 鹿角霜 | TCMH1346 |
Targeted Human Proteins by the Ingredients of Prescription
| Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
|---|---|---|---|---|
| TCMT101 | PTPN1 | Protein-tyrosine phosphatase 1B | Hydrolase | P18031 |
| TCMT102 | ACP1 | Low molecular weight phosphotyrosine protein phosphatase | Hydrolase | P24666 |
| TCMT103 | PTPRF | Receptor-type tyrosine-protein phosphatase F (LAR) | Hydrolase | P10586 |
| TCMT112 | ADORA3 | Adenosine A3 receptor | GPCR | P0DMS8 |
| TCMT127 | PARP1 | Poly [ADP-ribose] polymerase-1 | Transferase | P09874 |
| TCMT128 | TNKS2 | Tankyrase-2 | Transferase | Q9H2K2 |
| TCMT129 | TNKS | Tankyrase-1 | Transferase | O95271 |
| TCMT13 | APEX1 | DNA-(apurinic or apyrimidinic site) lyase | Lyase | P27695 |
| TCMT130 | ALOX5 | Arachidonate 5-lipoxygenase | Oxidoreductase | P09917 |
| TCMT131 | ACHE | Acetylcholinesterase | Hydrolase | P22303 |
Showing 1 to 10 of 116 entries
Targeted Pathogenic Microbes by the Ingredients of Prescription
| Target ID | Target Name |
|---|---|
| TCMT1178 | Actinomyces viscosus |
| TCMT1181 | Mycobacterium tuberculosis H37Ra |
| TCMT1189 | Pseudomonas fluorescens |
| TCMT1190 | Plasmodium falciparum (isolate FcB1 / Columbia) |
| TCMT1208 | Escherichia coli K12 |
| TCMT1209 | Staphylococcus haemolyticus |
| TCMT1210 | Streptococcus sobrinus |
| TCMT1211 | Fusobacterium nucleatum |
| TCMT1212 | Verticillium dahliae |
| TCMT1215 | Pseudomonas aeruginosa PAO1 |
Showing 1 to 10 of 60 entries
Gene Ontology Associated to Targeted Human Proteins
| GO Term | GO Name | Enriched Genes | Log10 Adjusted P-value |
|---|---|---|---|
| [BP] GO:0000302 | response to reactive oxygen species | AKR1B1, APEX1, AXL, CYP1B1, EGFR, MMP9, RELA, SRC | 4.34355 |
| [BP] GO:0000904 | cell morphogenesis involved in differentiation | AR, AXL, MET, SRC, TEK | 2.54304 |
| [BP] GO:0001101 | response to acid chemical | AKR1B1, EGFR, FABP3, KDR, MMP2, PTGES, RELA, SRC | 2.68294 |
| [BP] GO:0001503 | ossification | ALOX15, EGFR, MMP2, MMP9, TEK | 2.32025 |
| [BP] GO:0001676 | long-chain fatty acid metabolic process | ALOX15, CYP1B1, CYP2A13, CYP2A6, CYP2D6, PTGES | 3.60992 |
| [BP] GO:0001932 | regulation of protein phosphorylation | ADORA1, ALOX15, APP, AR, CDC25B, DUSP3, EGFR, FABP4, FLT3, IGF1R, INSR, KDR, MAP2K1, MAP3K7, MMP9, PTPN1, SRC, TEK, XDH | 4.25289 |
| [BP] GO:0001934 | positive regulation of protein phosphorylation | ADORA1, ALOX15, APP, AR, CDC25B, EGFR, FLT3, INSR, KDR, MAP2K1, MAP3K7, MMP9, PTPN1, SRC, TEK, XDH | 4.34685 |
| [BP] GO:0002009 | morphogenesis of an epithelium | AR, CA2, CA9, EGFR, MET, SMAD3, SRC | 2.24735 |
| [BP] GO:0002520 | None | CACNA1C, SMAD3 | 2.46529 |
| [BP] GO:0006081 | None | AKR1B10, CYP1B1, GLO1, RELA | 2.17315 |
Showing 1 to 10 of 328 entries
KEGG Pathways Associated to Targeted Human Proteins
| KEGG Pathway ID | Enriched Genes | Log10 Adjusted P-value |
|---|---|---|
| Acute myeloid leukemia_Homo sapiens_hsa05221 | MAP2K1, FLT3, PIM1, RELA | 3.3354 |
| Adherens junction_Homo sapiens_hsa04520 | PTPN1, SMAD3, CSNK2A1, SRC, INSR, MAP3K7, MET, EGFR, IGF1R | 9.4253 |
| Adipocytokine signaling pathway_Homo sapiens_hsa04920 | PPARA, RELA | 1.3293 |
| Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | CACNA1C | 0.3815 |
| AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | SMAD3, MMP2, PIM1, F3, RELA | 3.5156 |
| Alcoholism_Homo sapiens_hsa05034 | MAP2K1, MAOA | 0.7607 |
| Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | CACNA1C | 0.5251 |
| Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | INSR | 0.7607 |
| Alzheimer's disease_Homo sapiens_hsa05010 | APP, CACNA1C | 0.7894 |
| Amoebiasis_Homo sapiens_hsa05146 | RELA | 0.4992 |
Showing 1 to 10 of 176 entries
Target Exprsssion in Healthy Human Tissues (protein & mRNA level)
Protein expression data was from the "Human Proteome Map" datasetmRNA expression data was from the "GTEx" dataset
Average Target Expression (Fold Change) in Multiple Disease Conditions
Fold Change with Corresponding Normal SamplesClick each cell within the heatmap to access gene expression of individual patient samples