Structure

Physi-Chem Properties

Molecular Weight:  254.06
Volume:  256.396
LogP:  3.58
LogD:  2.947
LogS:  -3.506
# Rotatable Bonds:  1
TPSA:  70.67
# H-Bond Aceptor:  4
# H-Bond Donor:  2
# Rings:  3
# Heavy Atoms:  4

MedChem Properties

QED Drug-Likeness Score:  0.7
Synthetic Accessibility Score:  2.096
Fsp3:  0.0
Lipinski Rule-of-5:  Accepted
Pfizer Rule:  Rejected
GSK Rule:  Accepted
BMS Rule:  0
Golden Triangle Rule:  Accepted
Chelating Alert:  0
PAINS Alert:  0

ADMET Properties (ADMETlab2.0)

ADMET: Absorption

Caco-2 Permeability:  -4.874
MDCK Permeability:  1.332931515207747e-05
Pgp-inhibitor:  0.003
Pgp-substrate:  0.869
Human Intestinal Absorption (HIA):  0.012
20% Bioavailability (F20%):  0.993
30% Bioavailability (F30%):  0.999

ADMET: Distribution

Blood-Brain-Barrier Penetration (BBB):  0.02
Plasma Protein Binding (PPB):  98.0276870727539%
Volume Distribution (VD):  0.493
Pgp-substrate:  2.7763702869415283%

ADMET: Metabolism

CYP1A2-inhibitor:  0.989
CYP1A2-substrate:  0.262
CYP2C19-inhibitor:  0.736
CYP2C19-substrate:  0.06
CYP2C9-inhibitor:  0.711
CYP2C9-substrate:  0.922
CYP2D6-inhibitor:  0.868
CYP2D6-substrate:  0.61
CYP3A4-inhibitor:  0.619
CYP3A4-substrate:  0.117

ADMET: Excretion

Clearance (CL):  5.131
Half-life (T1/2):  0.787

ADMET: Toxicity

hERG Blockers:  0.037
Human Hepatotoxicity (H-HT):  0.079
Drug-inuced Liver Injury (DILI):  0.869
AMES Toxicity:  0.559
Rat Oral Acute Toxicity:  0.088
Maximum Recommended Daily Dose:  0.424
Skin Sensitization:  0.926
Carcinogencity:  0.317
Eye Corrosion:  0.016
Eye Irritation:  0.948
Respiratory Toxicity:  0.513

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Biological Activities  
Similar NPs/Drugs  

  Natural Product: NPC78540

Natural Product ID:  NPC78540
Common Name*:   Chrysin
IUPAC Name:   5,7-dihydroxy-2-phenylchromen-4-one
Synonyms:   NSC-407436
Standard InCHIKey:  RTIXKCRFFJGDFG-UHFFFAOYSA-N
Standard InCHI:  InChI=1S/C15H10O4/c16-10-6-11(17)15-12(18)8-13(19-14(15)7-10)9-4-2-1-3-5-9/h1-8,16-17H
SMILES:  Oc1cc(O)c2c(c1)oc(cc2=O)c1ccccc1
Synthetic Gene Cluster:   n.a.
ChEMBL Identifier:   CHEMBL117
PubChem CID:   5281607
Chemical Classification**:  
  • CHEMONTID:0000000 [Organic compounds]
    • [CHEMONTID:0000261] Phenylpropanoids and polyketides
      • [CHEMONTID:0000334] Flavonoids
        • [CHEMONTID:0001615] Flavones

*Note: the InCHIKey will be temporarily assigned as the "Common Name" if no IUPAC name or alternative short name is available.
**Note: the Chemical Classification was calculated by NPClassifier Version 1.5. Reference: PMID:34662515.

  Species Source

Organism ID Organism Name Taxonomy Level Family SuperKingdom Isolation Part Collection Location Collection Time Reference
NPO1515 Lonicera japonica Species Caprifoliaceae Eukaryota Flowers n.a. n.a. DOI[10.1002/elan.200403102]
NPO28778 Eucalyptus viminalis Species Myrtaceae Eukaryota n.a. n.a. n.a. DOI[10.1007/BF00579992]
NPO21072 Rhododendron dauricum Species Ericaceae Eukaryota n.a. whole plant n.a. DOI[10.1007/BF02329610]
NPO784 Sinapis alba Species Brassicaceae Eukaryota n.a. seed n.a. DOI[10.1007/s11418-005-0009-z]
NPO22715 Alpinia oxyphylla Species Zingiberaceae Eukaryota n.a. n.a. n.a. DOI[10.1016/0031-9422(81)85171-0]
NPO1515 Lonicera japonica Species Caprifoliaceae Eukaryota Flowers n.a. n.a. DOI[10.1016/j.foodchem.2012.02.124]
NPO4391 Hypericum perforatum Species Hypericaceae Eukaryota n.a. n.a. n.a. DOI[10.1078/0176-1617-00195]
NPO10494 Alpinia katsumadai Species Staphylinidae Eukaryota n.a. n.a. n.a. PMID[10654416]
NPO1086 Botrytis cinerea Species Sclerotiniaceae Eukaryota n.a. n.a. n.a. PMID[10691704]
NPO4391 Hypericum perforatum Species Hypericaceae Eukaryota n.a. n.a. n.a. PMID[10757735]
NPO1515 Lonicera japonica Species Caprifoliaceae Eukaryota Flowers n.a. n.a. PMID[11077184]
NPO24559 Cotinus coggygria Species Anacardiaceae Eukaryota Whole plant n.a. n.a. PMID[11141121]
NPO6092 Symphyocladia latiuscula Species Rhodomelaceae Eukaryota n.a. n.a. n.a. PMID[11141124]
NPO809 Leitneria floridana Species Simaroubaceae Eukaryota n.a. aerial part n.a. PMID[11141127]
NPO22715 Alpinia oxyphylla Species Zingiberaceae Eukaryota n.a. n.a. n.a. PMID[11514174]
NPO3699 Acacia aulacocarpa Species Fabaceae Eukaryota n.a. leaf n.a. PMID[11735581]
NPO7869 Peritassa campestris Species Celastraceae Eukaryota n.a. root n.a. PMID[11738408]
NPO32539 chinese propolis Species Rhytismataceae Eukaryota n.a. n.a. n.a. PMID[12027739]
NPO22715 Alpinia oxyphylla Species Zingiberaceae Eukaryota fruit Hainan Island, China 1998 PMID[12398545]
NPO9096 Scutellaria lateriflora Species Lamiaceae Eukaryota n.a. n.a. n.a. PMID[12713409]
NPO40877 Malagasy connaraceous Species n.a. n.a. n.a. n.a. n.a. PMID[14510616]
NPO10494 Alpinia katsumadai Species Staphylinidae Eukaryota n.a. seed n.a. PMID[14577694]
NPO4391 Hypericum perforatum Species Hypericaceae Eukaryota n.a. n.a. n.a. PMID[14735439]
NPO21072 Rhododendron dauricum Species Ericaceae Eukaryota n.a. n.a. n.a. PMID[15270561]
NPO27517 Crinum latifolium Species Amaryllidaceae Eukaryota n.a. leaf n.a. PMID[15595606]
NPO4391 Hypericum perforatum Species Hypericaceae Eukaryota n.a. callus n.a. PMID[15715262]
NPO8513 Pseudomonas fluorescens Species Pseudomonadaceae Bacteria n.a. n.a. n.a. PMID[15826166]
NPO6092 Symphyocladia latiuscula Species Rhodomelaceae Eukaryota n.a. n.a. n.a. PMID[15844965]
NPO11318 Eriodictyon californicum Species Namaceae Eukaryota n.a. n.a. n.a. PMID[1593282]
NPO1086 Botrytis cinerea Species Sclerotiniaceae Eukaryota n.a. n.a. n.a. PMID[16378371]
NPO5635 Bauhinia purpurea Species Fabaceae Eukaryota n.a. n.a. n.a. PMID[16562827]
NPO1086 Botrytis cinerea Species Sclerotiniaceae Eukaryota n.a. n.a. n.a. PMID[16643065]
NPO1515 Lonicera japonica Species Caprifoliaceae Eukaryota Flowers n.a. n.a. PMID[17328234]
NPO28641 Tubocapsicum anomalum Species Solanaceae Eukaryota stems, roots, and leaves Da-Han Mountain, Kaohsiung, Taiwan 2004-OCT PMID[17417907]
NPO28641 Tubocapsicum anomalum Species Solanaceae Eukaryota n.a. n.a. n.a. PMID[17417907]
NPO5635 Bauhinia purpurea Species Fabaceae Eukaryota roots Phitsanulok Province, Thailand 2004-MAY PMID[17480099]
NPO5635 Bauhinia purpurea Species Fabaceae Eukaryota n.a. root n.a. PMID[17480099]
NPO12006 Apis mellifera Species Apidae Eukaryota n.a. n.a. n.a. PMID[17548953]
NPO6092 Symphyocladia latiuscula Species Rhodomelaceae Eukaryota n.a. n.a. n.a. PMID[17602526]
NPO8513 Pseudomonas fluorescens Species Pseudomonadaceae Bacteria n.a. n.a. n.a. PMID[17924666]
NPO22375 Saussurea salicifolia Species Asteraceae Eukaryota n.a. aerial part n.a. PMID[18057725]
NPO4391 Hypericum perforatum Species Hypericaceae Eukaryota n.a. n.a. n.a. PMID[18220354]
NPO8025 Aaptos ciliata Species Suberitidae Eukaryota n.a. n.a. n.a. PMID[18257536]
NPO24900 Vladimiria muliensis n.a. n.a. n.a. n.a. n.a. n.a. PMID[18293903]
NPO1515 Lonicera japonica Species Caprifoliaceae Eukaryota Flower buds n.a. n.a. PMID[18321056]
NPO14969 Hedychium spicatum Species Zingiberaceae Eukaryota n.a. rhizome n.a. PMID[19027298]
NPO5325 Lobophytum durum Species Alcyoniidae Eukaryota n.a. n.a. n.a. PMID[19177635]
NPO2188 Dendrobium candidum Species Orchidaceae Eukaryota n.a. stem n.a. PMID[19182417]
NPO14969 Hedychium spicatum Species Zingiberaceae Eukaryota rhizomes n.a. n.a. PMID[19332371]
NPO24900 Vladimiria muliensis n.a. n.a. n.a. n.a. n.a. n.a. PMID[19432411]
NPO5325 Lobophytum durum Species Alcyoniidae Eukaryota n.a. n.a. n.a. PMID[19433363]
NPO9096 Scutellaria lateriflora Species Lamiaceae Eukaryota aerial parts n.a. n.a. PMID[19555121]
NPO9096 Scutellaria lateriflora Species Lamiaceae Eukaryota n.a. n.a. n.a. PMID[19555121]
NPO11748 Eunicea knighti Species Plexauridae Eukaryota n.a. Santa Marta Bay, Colombian Caribbean 2007-MAY PMID[19778088]
NPO14969 Hedychium spicatum Species Zingiberaceae Eukaryota rhizomes n.a. n.a. PMID[19782567]
NPO28877 Scutellaria baicalensis Species Lamiaceae Eukaryota n.a. n.a. n.a. PMID[19829679]
NPO28574 Oroxylum indicum Species Bignoniaceae Eukaryota n.a. n.a. n.a. PMID[19948405]
NPO10494 Alpinia katsumadai Species Staphylinidae Eukaryota n.a. n.a. n.a. PMID[20014777]
NPO13379 Schizanthus tricolor Species Solanaceae Eukaryota Aerial parts n.a. n.a. PMID[20166702]
NPO40884 Mexican propolis Species n.a. n.a. n.a. n.a. n.a. PMID[20307087]
NPO28807 Laggera pterodonta Species Asteraceae Eukaryota n.a. n.a. n.a. PMID[20506820]
NPO2765 Oxytropis falcata Species Fabaceae Eukaryota n.a. Sunan County, Gansu Province, China 2006-JUN PMID[20684529]
NPO8513 Pseudomonas fluorescens Species Pseudomonadaceae Bacteria n.a. n.a. n.a. PMID[20979386]
NPO28877 Scutellaria baicalensis Species Lamiaceae Eukaryota n.a. root n.a. PMID[21087019]
NPO11266 Garcinia cambogia Species Clusiaceae Eukaryota n.a. exocarp n.a. PMID[21114277]
NPO13379 Schizanthus tricolor Species Solanaceae Eukaryota n.a. aerial part n.a. PMID[21171571]
NPO14130 Phagnalon rupestre Species Asteraceae Eukaryota n.a. aerial part n.a. PMID[21469692]
NPO14130 Phagnalon rupestre Species Asteraceae Eukaryota n.a. n.a. n.a. PMID[21469692]
NPO1515 Lonicera japonica Species Caprifoliaceae Eukaryota n.a. flower n.a. PMID[21804227]
NPO10494 Alpinia katsumadai Species Staphylinidae Eukaryota seeds n.a. n.a. PMID[21942765]
NPO10494 Alpinia katsumadai Species Staphylinidae Eukaryota n.a. seed n.a. PMID[21942765]
NPO1515 Lonicera japonica Species Caprifoliaceae Eukaryota flower buds Henan province, China 2005-MAY PMID[21942812]
NPO1515 Lonicera japonica Species Caprifoliaceae Eukaryota n.a. flower bud n.a. PMID[21942812]
NPO5608 Croton gratissimus Species Euphorbiaceae Eukaryota n.a. stem n.a. PMID[22032651]
NPO5608 Croton gratissimus Species Euphorbiaceae Eukaryota n.a. leaf n.a. PMID[22032651]
NPO22715 Alpinia oxyphylla Species Zingiberaceae Eukaryota n.a. n.a. n.a. PMID[22277277]
NPO28877 Scutellaria baicalensis Species Lamiaceae Eukaryota n.a. n.a. n.a. PMID[22314230]
NPO10494 Alpinia katsumadai Species Staphylinidae Eukaryota n.a. n.a. n.a. PMID[22459211]
NPO2765 Oxytropis falcata Species Fabaceae Eukaryota whole plant Guide County, Qinghai Province, China 2008-AUG PMID[22775441]
NPO1515 Lonicera japonica Species Caprifoliaceae Eukaryota n.a. leaf n.a. PMID[23265495]
NPO14969 Hedychium spicatum Species Zingiberaceae Eukaryota n.a. rhizome n.a. PMID[23422227]
NPO25106 Arnica parryi Species Asteraceae Eukaryota n.a. n.a. n.a. PMID[23501116]
NPO28877 Scutellaria baicalensis Species Lamiaceae Eukaryota n.a. n.a. n.a. PMID[23521110]
NPO22715 Alpinia oxyphylla Species Zingiberaceae Eukaryota n.a. n.a. n.a. PMID[23583435]
NPO28574 Oroxylum indicum Species Bignoniaceae Eukaryota n.a. seed n.a. PMID[23672042]
NPO8513 Pseudomonas fluorescens Species Pseudomonadaceae Bacteria n.a. n.a. n.a. PMID[23688329]
NPO8513 Pseudomonas fluorescens Species Pseudomonadaceae Bacteria n.a. n.a. n.a. PMID[23897464]
NPO1515 Lonicera japonica Species Caprifoliaceae Eukaryota Flower buds n.a. n.a. PMID[24279769]
NPO27031 Methanosarcina barkeri Species Methanosarcinaceae Archaea n.a. n.a. n.a. PMID[24669201]
NPO12006 Apis mellifera Species Apidae Eukaryota n.a. n.a. n.a. PMID[24675423]
NPO12006 Apis mellifera Species Apidae Eukaryota n.a. Bako, Ethiopia PMID[24926420]
NPO12006 Apis mellifera Species Apidae Eukaryota n.a. Enemore, Ethiopia PMID[24926420]
NPO12006 Apis mellifera Species Apidae Eukaryota n.a. Gedo, Ethiopia PMID[24926420]
NPO12006 Apis mellifera Species Apidae Eukaryota n.a. Holleta, Ethiopia PMID[24926420]
NPO9096 Scutellaria lateriflora Species Lamiaceae Eukaryota aerial part n.a. n.a. PMID[25442304]
NPO22715 Alpinia oxyphylla Species Zingiberaceae Eukaryota n.a. n.a. n.a. PMID[25757283]
NPO28765 Miliusa balansae Species Annonaceae Eukaryota leaves n.a. n.a. PMID[26238320]
NPO4391 Hypericum perforatum Species Hypericaceae Eukaryota n.a. n.a. n.a. PMID[28445039]
NPO3013 Clathria basilana Species Microcionidae Eukaryota n.a. n.a. n.a. PMID[29094598]
NPO5305 Corydalis mucronifera Species Papaveraceae Eukaryota n.a. n.a. n.a. PMID[29400966]
NPO28171 Anacyclus pyrethrum Species Asteraceae Eukaryota n.a. n.a. n.a. PMID[29775308]
NPO4391 Hypericum perforatum Species Hypericaceae Eukaryota Roots n.a. n.a. PMID[30024167]
NPO8257 Carpha glomerata Species Cyperaceae Eukaryota n.a. n.a. n.a. PMID[30219526]
NPO15317 Desmos cochinchinensis Species Annonaceae Eukaryota Leaf; Twig n.a. n.a. PMID[30835120]
NPO28688 Aster tataricus Species Asteraceae Eukaryota n.a. n.a. n.a. PMID[30931559]
NPO41040 Sphaerocoryne gracilis ssp. gracilis Strain Annonaceae Eukaryota n.a. n.a. n.a. PMID[32067457]
NPO1086 Botrytis cinerea Species Sclerotiniaceae Eukaryota n.a. n.a. n.a. PMID[32705864]
NPO17543 Stizophyllum riparium Species Bignoniaceae Eukaryota n.a. n.a. n.a. PMID[3598599]
NPO14992 Prunus persica Species Rosaceae Eukaryota n.a. kernel n.a. PMID[7092570]
NPO8513 Pseudomonas fluorescens Species Pseudomonadaceae Bacteria n.a. n.a. n.a. PMID[7798954]
NPO30745 Chrysanthemum morifolium Species Asteraceae Eukaryota n.a. inflorescence n.a. PMID[8158164]
NPO30745 Chrysanthemum morifolium Species Asteraceae Eukaryota n.a. n.a. n.a. PMID[8158164]
NPO25565 Acrosiphonia coalita Species Ulotrichaceae Eukaryota n.a. n.a. n.a. PMID[8463797]
NPO8513 Pseudomonas fluorescens Species Pseudomonadaceae Bacteria n.a. n.a. n.a. PMID[8626242]
NPO28701 Salvia lanigera Species Lamiaceae Eukaryota n.a. root n.a. PMID[8824952]
NPO24843 Pachygone dasycarpa Species Menispermaceae Eukaryota n.a. n.a. n.a. PMID[9157192]
NPO24843 Pachygone dasycarpa Species Menispermaceae Eukaryota stem bark n.a. n.a. PMID[9157192]
NPO27927 Alligator sinensis Species Alligatoridae Eukaryota n.a. n.a. n.a. PMID[9287418]
NPO28877 Scutellaria baicalensis Species Lamiaceae Eukaryota n.a. n.a. n.a. PMID[9834167]
NPO7698 Elettaria cardamomum Species Zingiberaceae Eukaryota n.a. n.a. Database[FooDB]
NPO784 Sinapis alba Species Brassicaceae Eukaryota n.a. n.a. Database[FooDB]
NPO14992 Prunus persica Species Rosaceae Eukaryota n.a. n.a. Database[FooDB]
NPO20686 Phyllostachys edulis Species Poaceae Eukaryota n.a. n.a. Database[FooDB]
NPO7698 Elettaria cardamomum Species Zingiberaceae Eukaryota Fruit n.a. n.a. Database[FooDB]
NPO14992 Prunus persica Species Rosaceae Eukaryota Fruit n.a. n.a. Database[FooDB]
NPO14992 Prunus persica Species Rosaceae Eukaryota Leaf n.a. n.a. Database[FooDB]
NPO7698 Elettaria cardamomum Species Zingiberaceae Eukaryota Plant n.a. n.a. Database[FooDB]
NPO14992 Prunus persica Species Rosaceae Eukaryota Plant n.a. n.a. Database[FooDB]
NPO7698 Elettaria cardamomum Species Zingiberaceae Eukaryota Seed n.a. n.a. Database[FooDB]
NPO784 Sinapis alba Species Brassicaceae Eukaryota Seed n.a. n.a. Database[FooDB]
NPO14992 Prunus persica Species Rosaceae Eukaryota Seed n.a. n.a. Database[FooDB]
NPO7698 Elettaria cardamomum Species Zingiberaceae Eukaryota n.a. n.a. Database[FooDB]
NPO784 Sinapis alba Species Brassicaceae Eukaryota n.a. n.a. Database[FooDB]
NPO20686 Phyllostachys edulis Species Poaceae Eukaryota n.a. n.a. Database[FooDB]
NPO1515 Lonicera japonica Species Caprifoliaceae Eukaryota n.a. n.a. n.a. Database[HerDing]
NPO11842 Petasites laevigatus Species Asteraceae Eukaryota n.a. n.a. n.a. Database[HerDing]
NPO22715 Alpinia oxyphylla Species Zingiberaceae Eukaryota n.a. n.a. n.a. Database[HerDing]
NPO11266 Garcinia cambogia Species Clusiaceae Eukaryota n.a. n.a. n.a. Database[HerDing]
NPO13473 Anodendron affine Species Apocynaceae Eukaryota n.a. n.a. n.a. Database[HerDing]
NPO2924 Pinus excelsa Species Pinaceae Eukaryota n.a. n.a. n.a. Database[HerDing]
NPO10494 Alpinia katsumadai Species Staphylinidae Eukaryota n.a. n.a. n.a. Database[HerDing]
NPO12006 Apis mellifera Species Apidae Eukaryota n.a. n.a. n.a. Database[HerDing]
NPO28574 Oroxylum indicum Species Bignoniaceae Eukaryota n.a. n.a. n.a. Database[HerDing]
NPO28830 Acronychia haplophylla Species Rutaceae Eukaryota n.a. n.a. n.a. Database[HerDing]
NPO6859 Eurycoma harmandiana Species Simaroubaceae Eukaryota n.a. n.a. n.a. Database[HerDing]
NPO30745 Chrysanthemum morifolium Species Asteraceae Eukaryota n.a. n.a. n.a. Database[HerDing]
NPO28688 Aster tataricus Species Asteraceae Eukaryota n.a. n.a. n.a. Database[HerDing]
NPO28877 Scutellaria baicalensis Species Lamiaceae Eukaryota n.a. n.a. n.a. Database[HerDing]
NPO28326 Uncaria longiflora Species Rubiaceae Eukaryota n.a. n.a. n.a. Database[HerDing]
NPO29503 Alstonia spectabilis Species Apocynaceae Eukaryota n.a. n.a. n.a. Database[HerDing]
NPO28765 Miliusa balansae Species Annonaceae Eukaryota n.a. n.a. n.a. Database[HerDing]
NPO28669 Cuscuta australis Species Convolvulaceae Eukaryota n.a. n.a. n.a. Database[HerDing]
NPO1674 Dalbergia nitidula Species Fabaceae Eukaryota n.a. n.a. n.a. Database[HerDing]
NPO7845 Tephrosia elata Species Geometridae Eukaryota n.a. n.a. n.a. Database[HerDing]
NPO7541 Ormosia hosiei Species Fabaceae Eukaryota n.a. n.a. n.a. Database[HerDing]
NPO23547 Strychnos amazonica Species Loganiaceae Eukaryota n.a. n.a. n.a. Database[HerDing]
NPO784 Sinapis alba Species Brassicaceae Eukaryota n.a. n.a. n.a. Database[HerDing]
NPO28778 Eucalyptus viminalis Species Myrtaceae Eukaryota n.a. n.a. n.a. Database[HerDing]
NPO28464 Mentha sylvestris Species Lamiaceae Eukaryota n.a. n.a. n.a. Database[HerDing]
NPO2921 Angelica acutiloba Species Apiaceae Eukaryota n.a. n.a. n.a. Database[HerDing]
NPO24328 Gratiola officinalis Species Plantaginaceae Eukaryota n.a. n.a. n.a. Database[HerDing]
NPO21072 Rhododendron dauricum Species Ericaceae Eukaryota n.a. n.a. n.a. Database[HerDing]
NPO23478 Uncaria africana Species Rubiaceae Eukaryota n.a. n.a. n.a. Database[HerDing]
NPO4391 Hypericum perforatum Species Hypericaceae Eukaryota n.a. n.a. n.a. Database[HerDing]
NPO24559 Cotinus coggygria Species Anacardiaceae Eukaryota n.a. n.a. n.a. Database[HerDing]
NPO1473 Xanthorhiza simplicissima Species Ranunculaceae Eukaryota n.a. n.a. n.a. Database[HerDing]
NPO14992 Prunus persica Species Rosaceae Eukaryota n.a. n.a. n.a. Database[HerDing]
NPO3853 Aspidosperma subincanum Species Apocynaceae Eukaryota n.a. n.a. n.a. Database[HerDing]
NPO5305 Corydalis mucronifera Species Papaveraceae Eukaryota n.a. n.a. n.a. Database[HerDing]
NPO28895 Pinus monticola Species Pinaceae Eukaryota n.a. n.a. n.a. Database[HerDing]
NPO27517 Crinum latifolium Species Amaryllidaceae Eukaryota n.a. n.a. n.a. Database[HerDing]
NPO3344 Bryonia alba Species Cucurbitaceae Eukaryota n.a. n.a. n.a. Database[HerDing]
NPO7698 Elettaria cardamomum Species Zingiberaceae Eukaryota n.a. n.a. Database[Phenol-Explorer]
NPO28574 Oroxylum indicum Species Bignoniaceae Eukaryota n.a. n.a. n.a. Database[TCMID]
NPO28669 Cuscuta australis Species Convolvulaceae Eukaryota n.a. n.a. n.a. Database[TCMID]
NPO11842 Petasites laevigatus Species Asteraceae Eukaryota n.a. n.a. n.a. Database[TCMID]
NPO7569 Guatteria boliviana Species Annonaceae Eukaryota n.a. n.a. n.a. Database[TCMID]
NPO28877 Scutellaria baicalensis Species Lamiaceae Eukaryota n.a. n.a. n.a. Database[TCMID]
NPO2131 Dactylorhiza viridis Species Orchidaceae Eukaryota n.a. n.a. n.a. Database[TCMID]
NPO3853 Aspidosperma subincanum Species Apocynaceae Eukaryota n.a. n.a. n.a. Database[TCMID]
NPO22715 Alpinia oxyphylla Species Zingiberaceae Eukaryota n.a. n.a. n.a. Database[TCMID]
NPO23288 Justicia betonica Species Acanthaceae Eukaryota n.a. n.a. n.a. Database[TCMID]
NPO4823 Psiadia dentata Species Asteraceae Eukaryota n.a. n.a. n.a. Database[TCMID]
NPO7845 Tephrosia elata Species Geometridae Eukaryota n.a. n.a. n.a. Database[TCMID]
NPO2921 Angelica acutiloba Species Apiaceae Eukaryota n.a. n.a. n.a. Database[TCMID]
NPO23478 Uncaria africana Species Rubiaceae Eukaryota n.a. n.a. n.a. Database[TCMID]
NPO7541 Ormosia hosiei Species Fabaceae Eukaryota n.a. n.a. n.a. Database[TCMID]
NPO15317 Desmos cochinchinensis Species Annonaceae Eukaryota n.a. n.a. n.a. Database[TCMID]
NPO5305 Corydalis mucronifera Species Papaveraceae Eukaryota n.a. n.a. n.a. Database[TCMID]
NPO23547 Strychnos amazonica Species Loganiaceae Eukaryota n.a. n.a. n.a. Database[TCMID]
NPO28830 Acronychia haplophylla Species Rutaceae Eukaryota n.a. n.a. n.a. Database[TCMID]
NPO3344 Bryonia alba Species Cucurbitaceae Eukaryota n.a. n.a. n.a. Database[TCMID]
NPO6859 Eurycoma harmandiana Species Simaroubaceae Eukaryota n.a. n.a. n.a. Database[TCMID]
NPO11266 Garcinia cambogia Species Clusiaceae Eukaryota n.a. n.a. n.a. Database[TCMID]
NPO28778 Eucalyptus viminalis Species Myrtaceae Eukaryota n.a. n.a. n.a. Database[TCMID]
NPO19948 Neolentinus lepideus Species Gloeophyllaceae Eukaryota n.a. n.a. n.a. Database[TCMID]
NPO27988 Salvia pisidica Species Lamiaceae Eukaryota n.a. n.a. n.a. Database[TCMID]
NPO28932 Myrrhis odorata Species Apiaceae Eukaryota n.a. n.a. n.a. Database[TCMID]
NPO14969 Hedychium spicatum Species Zingiberaceae Eukaryota n.a. n.a. n.a. Database[TCMID]
NPO24328 Gratiola officinalis Species Plantaginaceae Eukaryota n.a. n.a. n.a. Database[TCMID]
NPO11215 Sansevieria trifasciata Species Asparagaceae Eukaryota n.a. n.a. n.a. Database[TCMID]
NPO1674 Dalbergia nitidula Species Fabaceae Eukaryota n.a. n.a. n.a. Database[TCMID]
NPO28765 Miliusa balansae Species Annonaceae Eukaryota n.a. n.a. n.a. Database[TCMID]
NPO28895 Pinus monticola Species Pinaceae Eukaryota n.a. n.a. n.a. Database[TCMID]
NPO14992 Prunus persica Species Rosaceae Eukaryota n.a. n.a. n.a. Database[TCMID]
NPO784 Sinapis alba Species Brassicaceae Eukaryota n.a. n.a. n.a. Database[TCMID]
NPO2924 Pinus excelsa Species Pinaceae Eukaryota n.a. n.a. n.a. Database[TCMID]
NPO21072 Rhododendron dauricum Species Ericaceae Eukaryota n.a. n.a. n.a. Database[TCMID]
NPO27517 Crinum latifolium Species Amaryllidaceae Eukaryota n.a. n.a. n.a. Database[TCMID]
NPO8418 Anemone flaccida Species Ranunculaceae Eukaryota n.a. n.a. n.a. Database[TCMID]
NPO28326 Uncaria longiflora Species Rubiaceae Eukaryota n.a. n.a. n.a. Database[TCMID]
NPO10494 Alpinia katsumadai Species Staphylinidae Eukaryota n.a. n.a. n.a. Database[TCMID]
NPO16841 Elsholtzia bodinieri Species Lamiaceae Eukaryota n.a. n.a. n.a. Database[TCMID]
NPO1473 Xanthorhiza simplicissima Species Ranunculaceae Eukaryota n.a. n.a. n.a. Database[TCMID]
NPO28464 Mentha sylvestris Species Lamiaceae Eukaryota n.a. n.a. n.a. Database[TCMID]
NPO28688 Aster tataricus Species Asteraceae Eukaryota n.a. n.a. n.a. Database[TCMID]
NPO4391 Hypericum perforatum Species Hypericaceae Eukaryota n.a. n.a. n.a. Database[TCMID]
NPO1515 Lonicera japonica Species Caprifoliaceae Eukaryota n.a. n.a. n.a. Database[TCMID]
NPO373 Viburnum erubescens Species Adoxaceae Eukaryota n.a. n.a. n.a. Database[TCMID]
NPO24010 Buglossoides arvensis Species Boraginaceae Eukaryota n.a. n.a. n.a. Database[TCMID]
NPO20686 Phyllostachys edulis Species Poaceae Eukaryota n.a. n.a. n.a. Database[TCMID]
NPO13473 Anodendron affine Species Apocynaceae Eukaryota n.a. n.a. n.a. Database[TCMID]
NPO29503 Alstonia spectabilis Species Apocynaceae Eukaryota n.a. n.a. n.a. Database[TCMID]
NPO24559 Cotinus coggygria Species Anacardiaceae Eukaryota n.a. n.a. n.a. Database[TCMID]
NPO8790 Cyanostegia angustifolia Species Lamiaceae Eukaryota n.a. n.a. n.a. Database[TCMID]
NPO28877 Scutellaria baicalensis Species Lamiaceae Eukaryota n.a. n.a. n.a. Database[TCM_Taiwan]
NPO14992 Prunus persica Species Rosaceae Eukaryota n.a. n.a. n.a. Database[TCM_Taiwan]
NPO7845 Tephrosia elata Species Geometridae Eukaryota n.a. n.a. n.a. Database[TCM_Taiwan]
NPO1515 Lonicera japonica Species Caprifoliaceae Eukaryota n.a. n.a. n.a. Database[TCM_Taiwan]
NPO5305 Corydalis mucronifera Species Papaveraceae Eukaryota n.a. n.a. n.a. Database[TCM_Taiwan]
NPO30745 Chrysanthemum morifolium Species Asteraceae Eukaryota n.a. n.a. n.a. Database[TCM_Taiwan]
NPO10494 Alpinia katsumadai Species Staphylinidae Eukaryota n.a. n.a. n.a. Database[TCM_Taiwan]
NPO28778 Eucalyptus viminalis Species Myrtaceae Eukaryota n.a. n.a. n.a. Database[TCM_Taiwan]
NPO28830 Acronychia haplophylla Species Rutaceae Eukaryota n.a. n.a. n.a. Database[TCM_Taiwan]
NPO784 Sinapis alba Species Brassicaceae Eukaryota n.a. n.a. n.a. Database[TCM_Taiwan]
NPO21072 Rhododendron dauricum Species Ericaceae Eukaryota n.a. n.a. n.a. Database[TCM_Taiwan]
NPO2921 Angelica acutiloba Species Apiaceae Eukaryota n.a. n.a. n.a. Database[TCM_Taiwan]
NPO11215 Sansevieria trifasciata Species Asparagaceae Eukaryota n.a. n.a. n.a. Database[TCM_Taiwan]
NPO1473 Xanthorhiza simplicissima Species Ranunculaceae Eukaryota n.a. n.a. n.a. Database[TCM_Taiwan]
NPO23547 Strychnos amazonica Species Loganiaceae Eukaryota n.a. n.a. n.a. Database[TCM_Taiwan]
NPO4391 Hypericum perforatum Species Hypericaceae Eukaryota n.a. n.a. n.a. Database[TCM_Taiwan]
NPO22715 Alpinia oxyphylla Species Zingiberaceae Eukaryota n.a. n.a. n.a. Database[TCM_Taiwan]
NPO24559 Cotinus coggygria Species Anacardiaceae Eukaryota n.a. n.a. n.a. Database[TCM_Taiwan]
NPO12006 Apis mellifera Species Apidae Eukaryota n.a. n.a. n.a. Database[TCM_Taiwan]
NPO7541 Ormosia hosiei Species Fabaceae Eukaryota n.a. n.a. n.a. Database[TCM_Taiwan]
NPO15317 Desmos cochinchinensis Species Annonaceae Eukaryota n.a. n.a. n.a. Database[TCM_Taiwan]
NPO28688 Aster tataricus Species Asteraceae Eukaryota n.a. n.a. n.a. Database[TCM_Taiwan]
NPO28574 Oroxylum indicum Species Bignoniaceae Eukaryota n.a. n.a. n.a. Database[TCM_Taiwan]
NPO28688 Aster tataricus Species Asteraceae Eukaryota n.a. n.a. n.a. Database[TM-MC]
NPO10494 Alpinia katsumadai Species Staphylinidae Eukaryota n.a. n.a. n.a. Database[TM-MC]
NPO28574 Oroxylum indicum Species Bignoniaceae Eukaryota n.a. n.a. n.a. Database[TM-MC]
NPO14992 Prunus persica Species Rosaceae Eukaryota n.a. n.a. n.a. Database[TM-MC]
NPO21072 Rhododendron dauricum Species Ericaceae Eukaryota n.a. n.a. n.a. Database[TM-MC]
NPO28807 Laggera pterodonta Species Asteraceae Eukaryota n.a. n.a. n.a. Database[TM-MC]
NPO4391 Hypericum perforatum Species Hypericaceae Eukaryota n.a. n.a. n.a. Database[TM-MC]
NPO784 Sinapis alba Species Brassicaceae Eukaryota n.a. n.a. n.a. Database[TM-MC]
NPO22715 Alpinia oxyphylla Species Zingiberaceae Eukaryota n.a. n.a. n.a. Database[TM-MC]
NPO28669 Cuscuta australis Species Convolvulaceae Eukaryota n.a. n.a. n.a. Database[TM-MC]
NPO2188 Dendrobium candidum Species Orchidaceae Eukaryota n.a. n.a. n.a. Database[TM-MC]
NPO28877 Scutellaria baicalensis Species Lamiaceae Eukaryota n.a. n.a. n.a. Database[TM-MC]
NPO7698 Elettaria cardamomum Species Zingiberaceae Eukaryota n.a. n.a. n.a. Database[TM-MC]
NPO1515 Lonicera japonica Species Caprifoliaceae Eukaryota n.a. n.a. n.a. Database[TM-MC]
NPO2921 Angelica acutiloba Species Apiaceae Eukaryota n.a. n.a. n.a. Database[TM-MC]
NPO24659 Eremurus chinensis Species Asphodelaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO9881 Petrosia hebes Species Petrosiidae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO2188 Dendrobium candidum Species Orchidaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO8086 Lepechinia caulescens Species Lamiaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO6237 Cryptocarya aschersoniana Species Lauraceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO9998 Abies excelsa Species Pinaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO28932 Myrrhis odorata Species Apiaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO13669 Hertia cheirifolia Species Asteraceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO23837 Rubus laciniatus Species Rosaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO1515 Lonicera japonica Species Caprifoliaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO14969 Hedychium spicatum Species Zingiberaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO24118 Buxus hildebrandtii Species Buxaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO3357 Alnus cordata Species Betulaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO28414 Medicosma fareana Species Rutaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO5305 Corydalis mucronifera Species Papaveraceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO10132 Schizophyllum lobatum Species Schizophyllaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO28574 Oroxylum indicum Species Bignoniaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO6859 Eurycoma harmandiana Species Simaroubaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO28623 Phlox decussata Species Polemoniaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO24843 Pachygone dasycarpa Species Menispermaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO1325 Bonnemaisonia asparagoides Species Bonnemaisoniaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO11215 Sansevieria trifasciata Species Asparagaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO28855 Salix petiolaris Species Salicaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO4901 Arnica mollis Species Asteraceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO29503 Alstonia spectabilis Species Apocynaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO3344 Bryonia alba Species Cucurbitaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO22924 Bombus terrestris Species Apidae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO5608 Croton gratissimus Species Euphorbiaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO25106 Arnica parryi Species Asteraceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO11318 Eriodictyon californicum Species Namaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO28807 Laggera pterodonta Species Asteraceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO28213 Humicola grisea Species Chaetomiaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO17023 Cusparia macrocarpa n.a. n.a. n.a. n.a. n.a. n.a. Database[UNPD]
NPO17543 Stizophyllum riparium Species Bignoniaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO24754 Tsitsikamma favus Species Latrunculiidae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO4823 Psiadia dentata Species Asteraceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO14130 Phagnalon rupestre Species Asteraceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO19716 Uvaria lucida Species Annonaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO28765 Miliusa balansae Species Annonaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO9091 Orthosiphon spicatus Species Lamiaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO28842 Oscillatoria raoi Species Oscillatoriaceae Bacteria n.a. n.a. n.a. Database[UNPD]
NPO5196 Eupatorium argentinum Species Asteraceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO24456 Salvia lavandulifolia Species Lamiaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO25102 Goniobranchus kuniei Species Chromodorididae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO11748 Eunicea knighti Species Plexauridae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO13178 Ornithoglossum viride Species Colchicaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO28464 Mentha sylvestris Species Lamiaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO27988 Salvia pisidica Species Lamiaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO24969 Ageratum mexicanum Species Asteraceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO28578 Uperoleia inundata Species Myobatrachidae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO3197 Polyporus confluens Species Polyporaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO2455 Thermopsis mollis Species Fabaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO10494 Alpinia katsumadai Species Staphylinidae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO25984 Trichocoleopsis sacculata Species Neotrichocoleaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO809 Leitneria floridana Species Simaroubaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO28489 Euphrasia regelii Species Orobanchaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO8790 Cyanostegia angustifolia Species Lamiaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO24021 Eucryphia cordifolia Species Cunoniaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO25031 Petunia nyctaginiflora Species Solanaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO2670 Maytenus chuchuhuasha Species Celastraceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO28739 Othonna macrophylla Species Asteraceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO28877 Scutellaria baicalensis Species Lamiaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO20686 Phyllostachys edulis Species Poaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO9737 Ampelocera edentula Species Ulmaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO28435 Solanum crinitum Species Solanaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO10038.1 Abies pinsapo var. marocana Varieties Pinaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO4330 Crotalus atrox Species Viperidae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO18045 Holothuria atra Species Holothuriidae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO28501 Hortonia angustifolia Species Monimiaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO8025 Aaptos ciliata Species Suberitidae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO21483 0nomuraea dietziae Species Streptosporangiaceae Bacteria n.a. n.a. n.a. Database[UNPD]
NPO22375 Saussurea salicifolia Species Asteraceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO23657 Ophiocordyceps heteropoda Species Ophiocordycipitaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO8513 Pseudomonas fluorescens Species Pseudomonadaceae Bacteria n.a. n.a. n.a. Database[UNPD]
NPO17445 Streptomyces corchorusii Species Streptomycetaceae Bacteria n.a. n.a. n.a. Database[UNPD]
NPO10488 Euphorbia lata Species Euphorbiaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO25068 Zebrina pendula Species Enidae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO28326 Uncaria longiflora Species Rubiaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO24328 Gratiola officinalis Species Plantaginaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO15046 Neonauclea zeylanica Species Rubiaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO16067.1 Pseudotsuga sinensis var. wilsoniana Varieties Pinaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO8418 Anemone flaccida Species Ranunculaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO1626 Primnoa reseda Species Primnoidae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO28280 Cetraria komarovii Species Parmeliaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO24010 Buglossoides arvensis Species Boraginaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO28259 Viguiera pinnatilobata Species Asteraceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO6828 Purpura aperta Species Muricidae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO131 Euphrasia stricta Species Orobanchaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO14992 Prunus persica Species Rosaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO2921 Angelica acutiloba Species Apiaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO4628 Aloe deltoideodonta Species Asphodelaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO7032 Marasmiellus troyanus Species Omphalotaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO21242 Neolitsea villosa Species Lauraceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO27517 Crinum latifolium Species Amaryllidaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO22715 Alpinia oxyphylla Species Zingiberaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO28112 Amauris niavius Species Nymphalidae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO24688 Streptomyces ramocissimus Species Streptomycetaceae Bacteria n.a. n.a. n.a. Database[UNPD]
NPO28669 Cuscuta australis Species Convolvulaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO8977 0tholaena aschenborniana Species Pteridaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO16841 Elsholtzia bodinieri Species Lamiaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO3597 Rheedia acuminata Species Clusiaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO9594 Lysimachia fordiana Species Primulaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO9608 Lepraria citrina Species Stereocaulaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO26581 Cyperus pilosus Species Cyperaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO28196 Brachylaena perrieri Species Asteraceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO24900 Vladimiria muliensis n.a. n.a. n.a. n.a. n.a. n.a. Database[UNPD]
NPO26148 Alternanthera sessilis Species Amaranthaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO2765 Oxytropis falcata Species Fabaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO4536 Remirea maritima Species Cyperaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO24191 Drypetes tessmanniana Species Putranjivaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO28233 Diplotropis ferruginea Species Fabaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO1973 Conyza japonica Species Asteraceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO27968 Phoma linga Species Didymellaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO28384 Ascotricha chartarum Species Xylariaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO3013 Clathria basilana Species Microcionidae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO17692.1 Rhizopus microsporus var. chinensis Varieties Rhizopodaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO28778 Eucalyptus viminalis Species Myrtaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO5280 Rubia tetragona Species Rubiaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO7569 Guatteria boliviana Species Annonaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO3906 Securigera securidaca Species Fabaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO21547 Crinum giganteum Species Amaryllidaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO195 Maprounea guianensis Species Euphorbiaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO9096 Scutellaria lateriflora Species Lamiaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO784 Sinapis alba Species Brassicaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO3853 Aspidosperma subincanum Species Apocynaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO21472 Pterolobium hexapetalum Species Fabaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO14470 Polypodium decumanum Species Polypodiidae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO28145 Dendrodoris limbata Species Dendrodorididae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO28895 Pinus monticola Species Pinaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO5635 Bauhinia purpurea Species Fabaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO28127 Ursinia speciosa Species Asteraceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO28688 Aster tataricus Species Asteraceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO15317 Desmos cochinchinensis Species Annonaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO24144 Ophiomastix mixta Species Ophiocomidae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO1490 Goldfussia yunnanensis n.a. n.a. n.a. n.a. n.a. n.a. Database[UNPD]
NPO3838 Chrysosporum ovalisporum Species Aphanizomenonaceae Bacteria n.a. n.a. n.a. Database[UNPD]
NPO14691.1 Crambe hispanica subsp. abyssinica Subspecies Brassicaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO2439 Diplopterygium glaucum Species Gleicheniaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO27093 Kniphofia foliosa Species Asphodelaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO4700 Pertusaria truncata Species Pertusariaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO4123 Trididemnum cyanophorum Species Didemnidae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO28065 Pentachondra pumila Species Ericaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO27277 Stenocarpella maydis Species Diaporthaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO178 Citrus funadoko Species Rutaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO28641 Tubocapsicum anomalum Species Solanaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO13455 Hemiselmis virescens Species Hemiselmidaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO5052 Physocarpus intermedius Species Rosaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO8938 Halobacillus litoralis Species Bacillaceae Bacteria n.a. n.a. n.a. Database[UNPD]
NPO12712 Cereus bridgesii Species Sagartiidae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO7698 Elettaria cardamomum Species Zingiberaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO3699 Acacia aulacocarpa Species Fabaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO26084 Vincetoxicum amplexicaule Species Apocynaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO28545 Scymnorhinus lichia n.a. n.a. n.a. n.a. n.a. n.a. Database[UNPD]
NPO8922 Kaempferia rotunda Species Zingiberaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO4391 Hypericum perforatum Species Hypericaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO23660 Alpinia zerumbet Species Zingiberaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO23549 Erysimum siliculosum Species Brassicaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO14169 Acrocarpia paniculata Species Sargassaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO17288 Piliostigma thonningii Species Fabaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO23092 Ammodendron karelinii Species Fabaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO7418 Eucalyptus resinifera Species Myrtaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO2131 Dactylorhiza viridis Species Orchidaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO15970 Chrysanthemum uliginosum Species Asteraceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO25226 Kalanchoe spathulata Species Crassulaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO11842 Petasites laevigatus Species Asteraceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO21072 Rhododendron dauricum Species Ericaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO13379 Schizanthus tricolor Species Solanaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO28337 Pimpinella peregrina Species Apiaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO24813 Agardhiella tenera Species Solieriaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO23547 Strychnos amazonica Species Loganiaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO13473 Anodendron affine Species Apocynaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO27031 Methanosarcina barkeri Species Methanosarcinaceae Archaea n.a. n.a. n.a. Database[UNPD]
NPO6729 Juniperus brevifolia Species Cupressaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO3962 Parinari campestris Species Chrysobalanaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO2128 Lebeckia plukenetiana Species Fabaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO13876 Cedrela salvadorensis Species Meliaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO16730 Helichrysum lindleyi Species Asteraceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO28701 Salvia lanigera Species Lamiaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO2924 Pinus excelsa Species Pinaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO23288 Justicia betonica Species Acanthaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO9726 Panzeria canescens Species Tachinidae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO24589 Grindelia discoidea Species Asteraceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO23750 Escontria chiotilla Species Cactaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO12006 Apis mellifera Species Apidae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO7869 Peritassa campestris Species Celastraceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO6807 Ranunculus asiaticus Species Ranunculaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO9569 Licaria chrysophylla Species Lauraceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO25475 Syphonota geographica Species Aplysiidae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO373 Viburnum erubescens Species Adoxaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO28266 Phlomis ostrowskiana Species Lamiaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO28171 Anacyclus pyrethrum Species Asteraceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO23149 Callistemon coccineus Species Myrtaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO1293 Streptomyces matensis Species Streptomycetaceae Bacteria n.a. n.a. n.a. Database[UNPD]
NPO8257 Carpha glomerata Species Cyperaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO5155 Peritassa compta Species Celastraceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO4382 Elmerrillia papuana n.a. n.a. n.a. n.a. n.a. n.a. Database[UNPD]
NPO7189 Saraca asoca Species Fabaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO27880 Mimusops laurifolia Species Sapotaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO14369 Pocillopora eydouxi Species Pocilloporidae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO7541 Ormosia hosiei Species Fabaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO8084 Axinyssa tethyoides Species Halichondriidae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO6790 Camchaya loloana Species Asteraceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO19948 Neolentinus lepideus Species Gloeophyllaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO6721 Hakea acicularis Species Proteaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO471 Ardisia neriifolia Species Primulaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO11266 Garcinia cambogia Species Clusiaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO15658 Utricularia vulgaris Species Lentibulariaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO6065 Brassica carinata Species Brassicaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO5086 Alternaria macrospora Species Pleosporaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO16610 Chromodoris hamiltoni Species Chromodorididae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO24937 Callicarpa acuminata Species Lamiaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO24406 Rhizophora tagal Species Rhizophoraceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO5325 Lobophytum durum Species Alcyoniidae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO26022 Indigofera kirilowi Species Fabaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO18875 Aconitum contortum Species Ranunculaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO25565 Acrosiphonia coalita Species Ulotrichaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO8807 Laurentia longiflora n.a. n.a. n.a. n.a. n.a. n.a. Database[UNPD]
NPO23375 Hypericum reptans Species Hypericaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO13474 Euphrasia genargentea Species Orobanchaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO24874 Croton geayi Species Euphorbiaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO27927 Alligator sinensis Species Alligatoridae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO24268 Pteryxia terebinthina Species Apiaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO24559 Cotinus coggygria Species Anacardiaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO9867 Ixeris debilis Species Asteraceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO7845 Tephrosia elata Species Geometridae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO25130 Hylotrupes bajulus Species Cerambycidae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO1473 Xanthorhiza simplicissima Species Ranunculaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO12521 Sphaeranthus confertifolius Species Asteraceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO3151 Solanum lanceolatum Species Solanaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO28830 Acronychia haplophylla Species Rutaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO24493 Echinacea simulata Species Asteraceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO23478 Uncaria africana Species Rubiaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO593 Wikstroemia viridiflora Species Thymelaeaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO11031 Radula complanata Species Radulaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO1674 Dalbergia nitidula Species Fabaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO5857 Achlya heterosexualis Species Saprolegniaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO28559 Julbernardia globifera Species Fabaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO25598 Sporidesmium bakeri Species n.a. Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO1086 Botrytis cinerea Species Sclerotiniaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO21799 Bacillus litoralis Species Bacillaceae Bacteria n.a. n.a. n.a. Database[UNPD]
NPO6092 Symphyocladia latiuscula Species Rhodomelaceae Eukaryota n.a. n.a. n.a. Database[UNPD]

☑ Note for Reference:
In addition to directly collecting NP source organism data from primary literature (where reference will provided as NCBI PMID or DOI links), NPASS also integrated them from below databases:
☉ UNPD: Universal Natural Products Database [PMID: 23638153].
☉ StreptomeDB: a database of streptomycetes natural products [PMID: 33051671].
☉ TM-MC: a database of medicinal materials and chemical compounds in Northeast Asian traditional medicine [PMID: 26156871].
☉ TCM@Taiwan: a Traditional Chinese Medicine database [PMID: 21253603].
☉ TCMID: a Traditional Chinese Medicine database [PMID: 29106634].
☉ TCMSP: The traditional Chinese medicine systems pharmacology database and analysis platform [PMID: 24735618].
☉ HerDing: a herb recommendation system to treat diseases using genes and chemicals [PMID: 26980517].
☉ MetaboLights: a metabolomics database [PMID: 27010336].
☉ FooDB: a database of constituents, chemistry and biology of food species [www.foodb.ca].

  NP Quantity Composition/Concentration

Organism ID NP ID Organism Material Preparation Organism Part NP Quantity (Standard) NP Quantity (Minimum) NP Quantity (Maximum) Quantity Unit Reference

☑ Note for Reference:
In addition to directly collecting NP quantitative data from primary literature (where reference will provided as NCBI PMID or DOI links), NPASS also integrated NP quantitative records for specific NP domains (e.g., NPS from foods or herbs) from domain-specific databases. These databases include:
☉ DUKE: Dr. Duke's Phytochemical and Ethnobotanical Databases.
☉ PHENOL EXPLORER: is the first comprehensive database on polyphenol content in foods [PMID: 24103452], its homepage can be accessed at here.
☉ FooDB: a database of constituents, chemistry and biology of food species [www.foodb.ca].

  Biological Activity

Target ID Target Type Target Name Target Organism Activity Type Activity Relation Value Unit Reference
NPT153 Individual Protein Androgen Receptor Homo sapiens Potency n.a. 10962.2 nM PubChem BioAssay data set
NPT153 Individual Protein Androgen Receptor Homo sapiens Potency n.a. 1933.1 nM PubChem BioAssay data set
NPT152 Individual Protein Nuclear factor erythroid 2-related factor 2 Homo sapiens Potency n.a. 68589.6 nM PubChem BioAssay data set
NPT153 Individual Protein Androgen Receptor Homo sapiens Potency n.a. 8707.6 nM PubChem BioAssay data set
NPT162 Individual Protein Heat shock protein beta-1 Homo sapiens Potency n.a. 13800.6 nM PubChem BioAssay data set
NPT106 Individual Protein Peroxisome proliferator-activated receptor delta Homo sapiens Potency n.a. 54941 nM PubChem BioAssay data set
NPT515 Cell Line SGC-7901 Homo sapiens IC50 = 5800.0 nM PMID[555328]
NPT139 Cell Line HT-29 Homo sapiens IC50 = 3100.0 nM PMID[555328]
NPT759 Cell Line H9 Homo sapiens EC50 = 5.0 ug.mL-1 PMID[555331]
NPT2732 Individual Protein Aldehyde dehydrogenase Homo sapiens Control = 73.5 % PMID[555332]
NPT2732 Individual Protein Aldehyde dehydrogenase Homo sapiens Control = 55.6 % PMID[555332]
NPT2732 Individual Protein Aldehyde dehydrogenase Homo sapiens Control = 33.6 % PMID[555332]
NPT2732 Individual Protein Aldehyde dehydrogenase Homo sapiens Control = 17.2 % PMID[555332]
NPT581 Individual Protein Cyclooxygenase-2 Mus musculus Inhibition = 11.0 % PMID[555333]
NPT111 Cell Line K562 Homo sapiens Relative daunomycin accumulation = 0.2 n.a. PMID[555336]
NPT1566 Individual Protein Glyoxalase I Homo sapiens Ki = 83176.38 nM PMID[555340]
NPT1571 Individual Protein Cyclin-dependent kinase 6 Homo sapiens IC50 = 6000.0 nM PMID[555342]
NPT441 Individual Protein Cytochrome P450 19A1 Homo sapiens Ki = 2600.0 nM PMID[555343]
NPT139 Cell Line HT-29 Homo sapiens Activity = 86.6 n.a. PMID[555344]
NPT139 Cell Line HT-29 Homo sapiens Activity = 62.8 n.a. PMID[555344]
NPT139 Cell Line HT-29 Homo sapiens Caspase induction = 0.8 n.a. PMID[555344]
NPT1265 Individual Protein Serine/threonine-protein kinase PIM1 Homo sapiens Activity = 16.0 % PMID[555345]
NPT1265 Individual Protein Serine/threonine-protein kinase PIM1 Homo sapiens Activity = 32.0 % PMID[555345]
NPT1334 Individual Protein 3-oxoacyl-acyl-carrier protein reductase Plasmodium falciparum IC50 = 10000.0 nM PMID[555347]
NPT3016 Individual Protein Selectin E Homo sapiens Inhibition = 15.0 % PMID[555348]
NPT3017 Individual Protein P-selectin Homo sapiens Inhibition = -5.3 % PMID[555348]
NPT3018 Individual Protein Leukocyte adhesion molecule-1 Homo sapiens Inhibition = 4.3 % PMID[555348]
NPT1265 Individual Protein Serine/threonine-protein kinase PIM1 Homo sapiens -Log IC50 = -1.18 uM PMID[555352]
NPT41 Individual Protein Aldose reductase Homo sapiens IC50 = 8500.0 nM PMID[555354]
NPT1576 Individual Protein Aldo-keto reductase family 1 member C21 Mus musculus Inhibition = 36.0 % PMID[555354]
NPT13 Individual Protein Tyrosine-protein kinase LCK Homo sapiens IC50 = 5.0 ug.mL-1 PMID[555358]
NPT31 Individual Protein Cyclooxygenase-2 Homo sapiens Inhibition < 30.0 % PMID[555361]
NPT91 Cell Line KB Homo sapiens ED50 = 13.0 ug ml-1 PMID[555363]
NPT612 Individual Protein Canalicular multispecific organic anion transporter 1 Homo sapiens Activity = 110.0 % PMID[555366]
NPT1581 Individual Protein Carbonyl reductase [NADPH] 1 Homo sapiens Tm < 2.0 degrees C PMID[555367]
NPT1581 Individual Protein Carbonyl reductase [NADPH] 1 Homo sapiens Tm = 4.6 degrees C PMID[555367]
NPT1581 Individual Protein Carbonyl reductase [NADPH] 1 Homo sapiens Activity = 16.3 % PMID[555367]
NPT1581 Individual Protein Carbonyl reductase [NADPH] 1 Homo sapiens IC50 = 670.0 nM PMID[555367]
NPT1581 Individual Protein Carbonyl reductase [NADPH] 1 Homo sapiens Ki = 110.0 nM PMID[555367]
NPT521 Cell Line RBL-2H3 Rattus norvegicus IC50 > 500000.0 nM PMID[555368]
NPT759 Cell Line H9 Homo sapiens IC50 = 47000.0 nM PMID[555369]
NPT1587 Individual Protein Estradiol 17-beta-dehydrogenase 1 Homo sapiens Activity = 34.0 % PMID[555370]
NPT1588 Individual Protein Estradiol 17-beta-dehydrogenase 2 Homo sapiens Activity = 32.8 % PMID[555370]
NPT189 Cell Line Vero Chlorocebus aethiops CC50 = 76.2 ug.mL-1 PMID[555371]
NPT453 Cell Line HT-1080 Homo sapiens EC50 = 94900.0 nM PMID[555372]
NPT81 Cell Line A549 Homo sapiens EC50 = 233000.0 nM PMID[555372]
NPT165 Cell Line HeLa Homo sapiens EC50 = 111000.0 nM PMID[555372]
NPT493 Individual Protein Neuraminidase Influenza A virus IC50 = 45700.0 nM PMID[555375]
NPT493 Individual Protein Neuraminidase Influenza A virus IC50 = 33360.0 nM PMID[555375]
NPT493 Individual Protein Neuraminidase Influenza A virus IC50 = 52900.0 nM PMID[555375]
NPT165 Cell Line HeLa Homo sapiens IC50 >= 10000.0 nM PMID[555377]
NPT3089 Cell Line SW1353 Homo sapiens IC50 = 33000.0 nM PMID[555378]
NPT249 Individual Protein Glucocorticoid receptor Homo sapiens EC150 = 1.5 uM PMID[555380]
NPT153 Individual Protein Androgen Receptor Homo sapiens EC150 = 1.5 uM PMID[555380]
NPT1970 Cell Line THP-1 Homo sapiens IC50 = 23380.0 nM PMID[555381]
NPT116 Cell Line HL-60 Homo sapiens IC50 = 33980.0 nM PMID[555381]
NPT1083 Cell Line A-375 Homo sapiens IC50 = 29650.0 nM PMID[555381]
NPT81 Cell Line A549 Homo sapiens IC50 = 19880.0 nM PMID[555381]
NPT1338 Individual Protein Sialidase 2 Homo sapiens IC50 = 890000.0 nM PMID[555386]
NPT1418 Individual Protein Anandamide amidohydrolase Homo sapiens Inhibition = 18.57 % PMID[555387]
NPT461 Cell Line PANC-1 Homo sapiens PC50 = 88.7 uM PMID[555389]
NPT1602 Individual Protein Neuraminidase Influenza A virus (A/Puerto Rico/8/1934(H1N1)) IC50 = 11.62 ug.mL-1 PMID[555390]
NPT1602 Individual Protein Neuraminidase Influenza A virus (A/Puerto Rico/8/1934(H1N1)) logIC50 = 1.065 n.a. PMID[555390]
NPT441 Individual Protein Cytochrome P450 19A1 Homo sapiens IC50 = 1.0 nM PMID[555392]
NPT1603 Individual Protein Cytochrome P450 1A1 Homo sapiens IC50 = 153.0 nM PMID[555395]
NPT208 Individual Protein Cytochrome P450 1A2 Homo sapiens IC50 = 84.0 nM PMID[555395]
NPT1604 Individual Protein Cytochrome P450 1B1 Homo sapiens IC50 = 24.0 nM PMID[555395]
NPT165 Cell Line HeLa Homo sapiens IC50 = 29000.0 nM PMID[555396]
NPT81 Cell Line A549 Homo sapiens IC50 > 100000.0 nM PMID[555396]
NPT139 Cell Line HT-29 Homo sapiens IC50 > 100000.0 nM PMID[555396]
NPT110 Individual Protein Cytochrome P450 2D6 Homo sapiens IC50 > 50000.0 nM PMID[555398]
NPT212 Individual Protein Cytochrome P450 2C9 Homo sapiens IC50 = 5225.0 nM PMID[555398]
NPT208 Individual Protein Cytochrome P450 1A2 Homo sapiens IC50 = 54.0 nM PMID[555398]
NPT109 Individual Protein Cytochrome P450 3A4 Homo sapiens IC50 > 50000.0 nM PMID[555398]
NPT48 Individual Protein Lysine-specific demethylase 4D-like Homo sapiens Potency = 31622.8 nM PMID[555400]
NPT484 Individual Protein Luciferin 4-monooxygenase Photinus pyralis Potency = 12589.3 nM PMID[555402]
NPT213 Individual Protein Cytochrome P450 2C19 Homo sapiens Potency = 794.3 nM PMID[555402]
NPT51 Individual Protein Microtubule-associated protein tau Homo sapiens Potency = 11220.2 nM PMID[555401]
NPT51 Individual Protein Microtubule-associated protein tau Homo sapiens Potency = 5623.4 nM PMID[555400]
NPT531 Individual Protein Nuclear receptor ROR-gamma Mus musculus Potency = 35481.3 nM PMID[555401]
NPT531 Individual Protein Nuclear receptor ROR-gamma Mus musculus Potency = 22387.2 nM PMID[555400]
NPT211 Individual Protein Hypoxia-inducible factor 1 alpha Homo sapiens Potency = 6309.6 nM PMID[555402]
NPT51 Individual Protein Microtubule-associated protein tau Homo sapiens Potency = 35481.3 nM PMID[555400]
NPT51 Individual Protein Microtubule-associated protein tau Homo sapiens Potency = 35481.3 nM PMID[555399]
NPT51 Individual Protein Microtubule-associated protein tau Homo sapiens Potency = 15848.9 nM PMID[555401]
NPT282 Individual Protein MAP kinase ERK2 Homo sapiens Potency = 31622.8 nM PMID[555400]
NPT531 Individual Protein Nuclear receptor ROR-gamma Mus musculus Potency = 15848.9 nM PMID[555401]
NPT151 Individual Protein 15-hydroxyprostaglandin dehydrogenase [NAD+] Homo sapiens Potency = 17782.8 nM PMID[555400]
NPT151 Individual Protein 15-hydroxyprostaglandin dehydrogenase [NAD+] Homo sapiens Potency = 3981.1 nM PMID[555399]
NPT539 Individual Protein Cellular tumor antigen p53 Homo sapiens Potency = 25118.9 nM PMID[555399]
NPT539 Individual Protein Cellular tumor antigen p53 Homo sapiens Potency = 25118.9 nM PMID[555400]
NPT539 Individual Protein Cellular tumor antigen p53 Homo sapiens Potency = 31622.8 nM PMID[555399]
NPT149 Individual Protein Endoplasmic reticulum-associated amyloid beta-peptide-binding protein Homo sapiens Potency = 10000.0 nM PMID[555402]
NPT109 Individual Protein Cytochrome P450 3A4 Homo sapiens Potency = 2511.9 nM PMID[555399]
NPT109 Individual Protein Cytochrome P450 3A4 Homo sapiens Potency = 7943.3 nM PMID[555401]
NPT109 Individual Protein Cytochrome P450 3A4 Homo sapiens Potency = 3162.3 nM PMID[555402]
NPT531 Individual Protein Nuclear receptor ROR-gamma Mus musculus Potency = 10000.0 nM PMID[555399]
NPT110 Individual Protein Cytochrome P450 2D6 Homo sapiens Potency = 12589.3 nM PMID[555402]
NPT212 Individual Protein Cytochrome P450 2C9 Homo sapiens Potency = 5011.9 nM PMID[555402]
NPT1621 Individual Protein Calmodulin Homo sapiens IC50 = 33430.0 nM PMID[555403]
NPT1621 Individual Protein Calmodulin Homo sapiens Ratio IC50 = 1.03 n.a. PMID[555403]
NPT41 Individual Protein Aldose reductase Homo sapiens IC50 = 7780.0 nM PMID[555405]
NPT1422 Individual Protein ATP-binding cassette sub-family G member 2 Homo sapiens IC50 = 1500.0 nM PMID[555406]
NPT1422 Individual Protein ATP-binding cassette sub-family G member 2 Homo sapiens IC50 = 2600.0 nM PMID[555406]
NPT212 Individual Protein Cytochrome P450 2C9 Homo sapiens AC50 = 5011.87 nM PMID[555402]
NPT208 Individual Protein Cytochrome P450 1A2 Homo sapiens AC50 = 19.95 nM PMID[555402]
NPT110 Individual Protein Cytochrome P450 2D6 Homo sapiens AC50 = 12589.25 nM PMID[555402]
NPT109 Individual Protein Cytochrome P450 3A4 Homo sapiens AC50 = 3162.28 nM PMID[555402]
NPT213 Individual Protein Cytochrome P450 2C19 Homo sapiens AC50 = 794.33 nM PMID[555402]
NPT1603 Individual Protein Cytochrome P450 1A1 Homo sapiens Ki = 42.0 nM PMID[555407]
NPT1604 Individual Protein Cytochrome P450 1B1 Homo sapiens Ki = 16.0 nM PMID[555407]
NPT784 Cell Line MDA-MB-468 Homo sapiens Ratio IC50 = 1.1 n.a. PMID[555407]
NPT1603 Individual Protein Cytochrome P450 1A1 Homo sapiens Activity = 15.9 % PMID[555407]
NPT581 Individual Protein Cyclooxygenase-2 Mus musculus Inhibition = 74.0 % PMID[555410]
NPT270 Individual Protein Nitric oxide synthase, inducible Mus musculus Inhibition = 8.9 % PMID[555410]
NPT546 Individual Protein Retinoid X receptor alpha Homo sapiens Potency n.a. 39810.7 nM PMID[555411]
NPT108 Individual Protein Estrogen receptor alpha Homo sapiens Potency n.a. 35481.3 nM PMID[555411]
NPT153 Individual Protein Androgen Receptor Homo sapiens Potency n.a. 15848.9 nM PMID[555411]
NPT65 Cell Line HepG2 Homo sapiens Potency n.a. 35481.3 nM PMID[555412]
NPT106 Individual Protein Peroxisome proliferator-activated receptor delta Homo sapiens Potency n.a. 31622.8 nM PMID[555411]
NPT108 Individual Protein Estrogen receptor alpha Homo sapiens Potency n.a. 39810.7 nM PMID[555411]
NPT106 Individual Protein Peroxisome proliferator-activated receptor delta Homo sapiens Potency n.a. 39810.7 nM PMID[555411]
NPT154 Individual Protein Mothers against decapentaplegic homolog 3 Homo sapiens Potency n.a. 28183.8 nM PMID[555412]
NPT198 Individual Protein Vitamin D receptor Homo sapiens Potency n.a. 39810.7 nM PMID[555411]
NPT540 Individual Protein Bile acid receptor FXR Homo sapiens Potency n.a. 17782.8 nM PMID[555411]
NPT249 Individual Protein Glucocorticoid receptor Homo sapiens Potency n.a. 12589.3 nM PMID[555411]
NPT546 Individual Protein Retinoid X receptor alpha Homo sapiens Potency n.a. 35481.3 nM PMID[555411]
NPT368 Cell Line SN12C Homo sapiens GI50 n.a. 17947.34 nM PMID[555414]
NPT369 Cell Line ACHN Homo sapiens GI50 n.a. 15205.48 nM PMID[555414]
NPT370 Cell Line NCI-H23 Homo sapiens GI50 n.a. 20892.96 nM PMID[555414]
NPT371 Cell Line UO-31 Homo sapiens GI50 n.a. 20370.42 nM PMID[555414]
NPT372 Cell Line HOP-92 Homo sapiens GI50 n.a. 16368.17 nM PMID[555414]
NPT116 Cell Line HL-60 Homo sapiens GI50 n.a. 16788.04 nM PMID[555414]
NPT374 Cell Line SF-539 Homo sapiens GI50 n.a. 15135.61 nM PMID[555414]
NPT373 Cell Line SK-MEL-5 Homo sapiens GI50 n.a. 10069.32 nM PMID[555414]
NPT375 Cell Line Malme-3M Homo sapiens GI50 n.a. 24266.1 nM PMID[555414]
NPT111 Cell Line K562 Homo sapiens GI50 n.a. 22750.97 nM PMID[555414]
NPT377 Cell Line OVCAR-3 Homo sapiens GI50 n.a. 28840.32 nM PMID[555414]
NPT112 Cell Line MOLT-4 Homo sapiens GI50 n.a. 18281.0 nM PMID[555414]
NPT379 Cell Line HOP-62 Homo sapiens GI50 n.a. 31405.09 nM PMID[555414]
NPT380 Cell Line U-251 Homo sapiens GI50 n.a. 21727.01 nM PMID[555414]
NPT382 Cell Line OVCAR-5 Homo sapiens GI50 n.a. 18620.87 nM PMID[555414]
NPT572 Cell Line DMS-273 Homo sapiens GI50 n.a. 16218.1 nM PMID[555414]
NPT383 Cell Line SNB-19 Homo sapiens GI50 n.a. 18450.15 nM PMID[555414]
NPT385 Cell Line SR Homo sapiens GI50 n.a. 23014.42 nM PMID[555414]
NPT384 Cell Line TK-10 Homo sapiens GI50 n.a. 34514.37 nM PMID[555414]
NPT573 Cell Line M19-MEL Homo sapiens GI50 n.a. 25468.3 nM PMID[555414]
NPT455 Cell Line NCI-H522 Homo sapiens GI50 n.a. 15922.09 nM PMID[555414]
NPT386 Cell Line KM12 Homo sapiens GI50 n.a. 15523.87 nM PMID[555414]
NPT574 Cell Line XF498 Homo sapiens GI50 n.a. 20044.72 nM PMID[555414]
NPT387 Cell Line M14 Homo sapiens GI50 n.a. 33036.95 nM PMID[555414]
NPT388 Cell Line NCI-H322M Homo sapiens GI50 n.a. 25763.21 nM PMID[555414]
NPT389 Cell Line RPMI-8226 Homo sapiens GI50 n.a. 15958.79 nM PMID[555414]
NPT456 Cell Line OVCAR-4 Homo sapiens GI50 n.a. 29785.16 nM PMID[555414]
NPT390 Cell Line LOX IMVI Homo sapiens GI50 n.a. 14655.48 nM PMID[555414]
NPT575 Cell Line KM-20L2 Homo sapiens GI50 n.a. 23933.16 nM PMID[555414]
NPT147 Cell Line SK-MEL-2 Homo sapiens GI50 n.a. 17906.06 nM PMID[555414]
NPT81 Cell Line A549 Homo sapiens GI50 n.a. 26977.39 nM PMID[555414]
NPT391 Cell Line HCC 2998 Homo sapiens GI50 n.a. 19815.27 nM PMID[555414]
NPT392 Cell Line SNB-75 Homo sapiens GI50 n.a. 10303.86 nM PMID[555414]
NPT148 Cell Line HCT-15 Homo sapiens GI50 n.a. 20417.38 nM PMID[555414]
NPT393 Cell Line HCT-116 Homo sapiens GI50 n.a. 15240.53 nM PMID[555414]
NPT395 Cell Line SF-268 Homo sapiens GI50 n.a. 23067.47 nM PMID[555414]
NPT394 Cell Line EKVX Homo sapiens GI50 n.a. 23067.47 nM PMID[555414]
NPT146 Cell Line SK-OV-3 Homo sapiens GI50 n.a. 27925.44 nM PMID[555414]
NPT731 Cell Line LXFL 529 Homo sapiens GI50 n.a. 21086.28 nM PMID[555414]
NPT576 Cell Line DMS-114 Homo sapiens GI50 n.a. 22387.21 nM PMID[555414]
NPT397 Cell Line NCI-H460 Homo sapiens GI50 n.a. 14190.58 nM PMID[555414]
NPT398 Cell Line UACC-62 Homo sapiens GI50 n.a. 21478.3 nM PMID[555414]
NPT458 Cell Line IGROV-1 Homo sapiens GI50 n.a. 10000.0 nM PMID[555414]
NPT399 Cell Line SF-295 Homo sapiens GI50 n.a. 14859.36 nM PMID[555414]
NPT401 Cell Line 786-0 Homo sapiens GI50 n.a. 23550.49 nM PMID[555414]
NPT403 Cell Line UACC-257 Homo sapiens GI50 n.a. 21134.89 nM PMID[555414]
NPT578 Cell Line SNB-78 Homo sapiens GI50 n.a. 28840.32 nM PMID[555414]
NPT404 Cell Line CCRF-CEM Homo sapiens GI50 n.a. 19364.22 nM PMID[555414]
NPT139 Cell Line HT-29 Homo sapiens GI50 n.a. 23442.29 nM PMID[555414]
NPT405 Cell Line NCI-H226 Homo sapiens GI50 n.a. 20606.3 nM PMID[555414]
NPT170 Cell Line SK-MEL-28 Homo sapiens GI50 n.a. 16788.04 nM PMID[555414]
NPT407 Cell Line COLO 205 Homo sapiens GI50 n.a. 18535.32 nM PMID[555414]
NPT441 Individual Protein Cytochrome P450 19A1 Homo sapiens IC50 = 1500.0 nM PMID[555415]
NPT233 Individual Protein Carbonic anhydrase II Homo sapiens Ki = 4380.0 nM PMID[555416]
NPT233 Individual Protein Carbonic anhydrase II Homo sapiens Ki = 4310.0 nM PMID[555416]
NPT1594 Individual Protein Multidrug resistance-associated protein 1 Homo sapiens Activity = 180.0 % PMID[555422]
NPT1594 Individual Protein Multidrug resistance-associated protein 1 Homo sapiens Activity = 198.0 % PMID[555422]
NPT10 Individual Protein Geminin Homo sapiens Potency n.a. 29092.9 nM PMID[555412]
NPT155 Individual Protein Aryl hydrocarbon receptor Homo sapiens Potency n.a. 39810.7 nM PMID[555411]
NPT152 Individual Protein Nuclear factor erythroid 2-related factor 2 Homo sapiens Potency n.a. 10870.7 nM PMID[555423]
NPT478 Individual Protein Ataxin-2 Homo sapiens Potency n.a. 3981.1 nM PMID[555402]
NPT157 Individual Protein Breast cancer type 1 susceptibility protein Homo sapiens Potency n.a. 11220.2 nM PMID[555412]
NPT11 Individual Protein Guanine nucleotide-binding protein G(s), subunit alpha Homo sapiens Potency n.a. 11220.2 nM PMID[555412]
NPT152 Individual Protein Nuclear factor erythroid 2-related factor 2 Homo sapiens Potency n.a. 14125.4 nM PMID[555412]
NPT65 Cell Line HepG2 Homo sapiens Activity > 20.0 uM PMID[555424]
NPT66 Individual Protein Acetylcholinesterase Electrophorus electricus Inhibition = 14.61 % PMID[555425]
NPT515 Cell Line SGC-7901 Homo sapiens IC50 > 100000.0 nM PMID[555426]
NPT111 Cell Line K562 Homo sapiens IC50 > 100000.0 nM PMID[555426]
NPT90 Cell Line DU-145 Homo sapiens IC50 = 9810.0 nM PMID[555426]
NPT165 Cell Line HeLa Homo sapiens IC50 = 43000.0 nM PMID[555426]
NPT393 Cell Line HCT-116 Homo sapiens IC50 > 100000.0 nM PMID[555426]
NPT1571 Individual Protein Cyclin-dependent kinase 6 Homo sapiens IC50 = 6000.0 nM PMID[555428]
NPT65 Cell Line HepG2 Homo sapiens GI < 50.0 % PMID[555432]
NPT112 Cell Line MOLT-4 Homo sapiens GI50 = 58600.0 nM PMID[555432]
NPT83 Cell Line MCF7 Homo sapiens GI50 = 69000.0 nM PMID[555432]
NPT106 Individual Protein Peroxisome proliferator-activated receptor delta Homo sapiens FC = 4.5 n.a. PMID[555434]
NPT106 Individual Protein Peroxisome proliferator-activated receptor delta Homo sapiens FC = 2.5 n.a. PMID[555434]
NPT1650 Individual Protein Tyrosine-protein kinase receptor FLT3 Homo sapiens IC50 > 10000.0 nM PMID[555435]
NPT627 Individual Protein Cytochrome P450 2B6 Homo sapiens IC50 > 25000.0 nM PMID[555436]
NPT240 Individual Protein Cytochrome P450 2A6 Homo sapiens IC50 > 25000.0 nM PMID[555436]
NPT208 Individual Protein Cytochrome P450 1A2 Homo sapiens IC50 = 570.0 nM PMID[555436]
NPT1603 Individual Protein Cytochrome P450 1A1 Homo sapiens IC50 = 1290.0 nM PMID[555436]
NPT50 Individual Protein Tyrosyl-DNA phosphodiesterase 1 Homo sapiens Potency n.a. 23109.3 nM PMID[555437]
NPT50 Individual Protein Tyrosyl-DNA phosphodiesterase 1 Homo sapiens Potency n.a. 18356.4 nM PMID[555438]
NPT50 Individual Protein Tyrosyl-DNA phosphodiesterase 1 Homo sapiens Potency n.a. 23715.0 nM PMID[555440]
NPT50 Individual Protein Tyrosyl-DNA phosphodiesterase 1 Homo sapiens Potency n.a. 33498.3 nM PMID[555440]
NPT50 Individual Protein Tyrosyl-DNA phosphodiesterase 1 Homo sapiens Potency n.a. 29092.9 nM PMID[555437]
NPT50 Individual Protein Tyrosyl-DNA phosphodiesterase 1 Homo sapiens Potency n.a. 29092.9 nM PMID[555438]
NPT585 Individual Protein Nuclear receptor subfamily 0 group B member 1 Homo sapiens IC50 > 67635.0 nM PMID[555439]
NPT50 Individual Protein Tyrosyl-DNA phosphodiesterase 1 Homo sapiens Potency n.a. 3264.3 nM PMID[555412]
NPT2257 Cell Line MCF-10A Homo sapiens GI = 29.56 % PMID[555444]
NPT2257 Cell Line MCF-10A Homo sapiens GI = 21.45 % PMID[555444]
NPT2257 Cell Line MCF-10A Homo sapiens GI = 14.46 % PMID[555444]
NPT2257 Cell Line MCF-10A Homo sapiens GI = 5.915 % PMID[555444]
NPT83 Cell Line MCF7 Homo sapiens GI = 96.98 % PMID[555444]
NPT83 Cell Line MCF7 Homo sapiens GI = 86.49 % PMID[555444]
NPT83 Cell Line MCF7 Homo sapiens GI = 45.21 % PMID[555444]
NPT83 Cell Line MCF7 Homo sapiens GI = 14.61 % PMID[555444]
NPT407 Cell Line COLO 205 Homo sapiens GI = 65.22 % PMID[555444]
NPT407 Cell Line COLO 205 Homo sapiens GI = 56.46 % PMID[555444]
NPT407 Cell Line COLO 205 Homo sapiens GI = 24.92 % PMID[555444]
NPT407 Cell Line COLO 205 Homo sapiens GI = 15.21 % PMID[555444]
NPT65 Cell Line HepG2 Homo sapiens GI = 65.12 % PMID[555444]
NPT65 Cell Line HepG2 Homo sapiens GI = 55.31 % PMID[555444]
NPT65 Cell Line HepG2 Homo sapiens GI = 29.17 % PMID[555444]
NPT65 Cell Line HepG2 Homo sapiens GI = 14.75 % PMID[555444]
NPT324 Individual Protein Cyclooxygenase-1 Ovis aries IC50 = 39300.0 nM PMID[555446]
NPT31 Individual Protein Cyclooxygenase-2 Homo sapiens IC50 = 25500.0 nM PMID[555446]
NPT570 Individual Protein Arachidonate 5-lipoxygenase Homo sapiens Inhibition < 50.0 % PMID[555447]
NPT1357 Cell Line H22 Mus musculus Activity = 17.13 % PMID[555449]
NPT1357 Cell Line H22 Mus musculus Activity = 69.91 % PMID[555449]
NPT1357 Cell Line H22 Mus musculus Activity = 12.97 % PMID[555449]
NPT1357 Cell Line H22 Mus musculus IC50 = 1671000.0 nM PMID[555449]
NPT441 Individual Protein Cytochrome P450 19A1 Homo sapiens IC50 = 800.0 nM PMID[555450]
NPT535 Individual Protein Parathyroid hormone receptor Homo sapiens Potency n.a. 2511.9 nM PMID[555412]
NPT152 Individual Protein Nuclear factor erythroid 2-related factor 2 Homo sapiens Potency n.a. 13685.4 nM PMID[555423]
NPT65 Cell Line HepG2 Homo sapiens Activity = 76.7 % PMID[555452]
NPT83 Cell Line MCF7 Homo sapiens Activity = 25.9 % PMID[555452]
NPT111 Cell Line K562 Homo sapiens Activity = 38.3 % PMID[555452]
NPT12 Individual Protein Human immunodeficiency virus type 1 integrase Human immunodeficiency virus 1 IC50 > 20000.0 nM PMID[555453]
NPT1452 Cell Line C8166 Homo sapiens CC50 = 110.0 ug.mL-1 PMID[555453]
NPT12 Individual Protein Human immunodeficiency virus type 1 integrase Human immunodeficiency virus 1 IC50 = 1400.0 nM PMID[555453]
NPT762 Cell Line A-431 Homo sapiens IC50 = 60130.0 nM PMID[555456]
NPT1719 Cell Line 2008 Homo sapiens IC50 = 28620.0 nM PMID[555456]
NPT762 Cell Line A-431 Homo sapiens Ratio IC50 = 2.0 n.a. PMID[555456]
NPT71 Cell Line HEK293 Homo sapiens IC50 = 77450.0 nM PMID[555456]
NPT71 Cell Line HEK293 Homo sapiens Ratio IC50 = 1.9 n.a. PMID[555456]
NPT1083 Cell Line A-375 Homo sapiens IC50 = 33230.0 nM PMID[555456]
NPT148 Cell Line HCT-15 Homo sapiens IC50 = 54430.0 nM PMID[555456]
NPT83 Cell Line MCF7 Homo sapiens IC50 = 50320.0 nM PMID[555456]
NPT762 Cell Line A-431 Homo sapiens IC50 = 29390.0 nM PMID[555456]
NPT1721 Individual Protein Death-associated protein kinase 1 Homo sapiens IC50 > 300000.0 nM PMID[555458]
NPT441 Individual Protein Cytochrome P450 19A1 Homo sapiens IC50 = 500.0 nM PMID[555459]
NPT233 Individual Protein Carbonic anhydrase II Homo sapiens Ki > 10000.0 nM PMID[555460]
NPT1062 Individual Protein Carbonic anhydrase IV Homo sapiens Ki = 537.75 nM PMID[555460]
NPT165 Cell Line HeLa Homo sapiens IC50 = 10.93 ug.mL-1 PMID[555462]
NPT660 Cell Line SW480 Homo sapiens IC50 = 31080.0 nM PMID[555463]
NPT139 Cell Line HT-29 Homo sapiens IC50 = 19490.0 nM PMID[555463]
NPT65 Cell Line HepG2 Homo sapiens IC50 = 16500.0 nM PMID[555463]
NPT65 Cell Line HepG2 Homo sapiens IC50 > 100000.0 nM PMID[555464]
NPT1443 Individual Protein Pyruvate dehydrogenase kinase isoform 1 Homo sapiens Inhibition = 2.02 % PMID[555468]
NPT208 Individual Protein Cytochrome P450 1A2 Homo sapiens Ki = 500.0 nM PMID[555471]
NPT1604 Individual Protein Cytochrome P450 1B1 Homo sapiens IC50 = 280.0 nM PMID[555471]
NPT1604 Individual Protein Cytochrome P450 1B1 Homo sapiens Ki = 16.0 nM PMID[555471]
NPT1310 Individual Protein Xanthine dehydrogenase Bos taurus Ratio IC50 = 2.83 n.a. PMID[555472]
NPT1310 Individual Protein Xanthine dehydrogenase Bos taurus IC50 = 1260.0 nM PMID[555472]
NPT1310 Individual Protein Xanthine dehydrogenase Bos taurus Ratio IC50 = 2.33 n.a. PMID[555472]
NPT1588 Individual Protein Estradiol 17-beta-dehydrogenase 2 Homo sapiens Activity = 32.8 % PMID[555474]
NPT83 Cell Line MCF7 Homo sapiens IC50 = 25660.0 nM PMID[555476]
NPT169 Cell Line B16-F10 Mus musculus IC50 = 17450.0 nM PMID[555476]
NPT81 Cell Line A549 Homo sapiens IC50 = 47800.0 nM PMID[555476]
NPT165 Cell Line HeLa Homo sapiens IC50 = 25050.0 nM PMID[555476]
NPT2615 Cell Line HEK-293T Homo sapiens IC50 = 319360.0 nM PMID[555476]
NPT492 Cell Line Caco-2 Homo sapiens IC50 = 9500.0 nM PMID[555477]
NPT165 Cell Line HeLa Homo sapiens IC50 = 14200.0 nM PMID[555478]
NPT2396 Cell Line KYSE-510 Homo sapiens IC50 = 63000.0 nM PMID[555478]
NPT81 Cell Line A549 Homo sapiens IC50 > 50000.0 nM PMID[555480]
NPT111 Cell Line K562 Homo sapiens IC50 > 50000.0 nM PMID[555480]
NPT2410 Cell Line NCI-H1299 Homo sapiens IC50 > 50000.0 nM PMID[555480]
NPT306 Cell Line PC-3 Homo sapiens IC50 > 50000.0 nM PMID[555480]
NPT171 Cell Line MRC5 Homo sapiens IC50 > 100000.0 nM PMID[555480]
NPT208 Individual Protein Cytochrome P450 1A2 Homo sapiens INH = 0.42 uM PMID[555481]
NPT1603 Individual Protein Cytochrome P450 1A1 Homo sapiens INH = 6.2 uM PMID[555481]
NPT1604 Individual Protein Cytochrome P450 1B1 Homo sapiens INH = 0.28 uM PMID[555481]
NPT1135 Cell Line Hepatocyte Rattus norvegicus FC = 1.6 n.a. PMID[555482]
NPT1135 Cell Line Hepatocyte Rattus norvegicus FC = 2.4 n.a. PMID[555482]
NPT1187 Individual Protein Proteasome Macropain subunit MB1 Homo sapiens IC50 = 4900.0 nM PMID[555487]
NPT1187 Individual Protein Proteasome Macropain subunit MB1 Homo sapiens IC50 = 6100.0 nM PMID[555487]
NPT111 Cell Line K562 Homo sapiens IC50 > 50000.0 nM PMID[555491]
NPT306 Cell Line PC-3 Homo sapiens IC50 > 50000.0 nM PMID[555491]
NPT81 Cell Line A549 Homo sapiens IC50 > 50000.0 nM PMID[555491]
NPT2410 Cell Line NCI-H1299 Homo sapiens IC50 > 50000.0 nM PMID[555491]
NPT171 Cell Line MRC5 Homo sapiens IC50 > 100000.0 nM PMID[555491]
NPT2266 Individual Protein Fructose-1,6-bisphosphatase Homo sapiens Inhibition < 20.0 % PMID[555492]
NPT2 Others Unspecified Potency n.a. 13803.9 nM PubChem BioAssay data set
NPT2 Others Unspecified Potency n.a. 19331.2 nM PubChem BioAssay data set
NPT2 Others Unspecified Potency n.a. 68589.6 nM PubChem BioAssay data set
NPT2 Others Unspecified Potency n.a. 27535.7 nM PubChem BioAssay data set
NPT2 Others Unspecified Potency n.a. 30637.9 nM PubChem BioAssay data set
NPT2 Others Unspecified Potency n.a. 54482.7 nM PubChem BioAssay data set
NPT2 Others Unspecified Potency n.a. 3857.1 nM PubChem BioAssay data set
NPT2 Others Unspecified Potency n.a. 21.9 nM PubChem BioAssay data set
NPT2 Others Unspecified Potency n.a. 54941 nM PubChem BioAssay data set
NPT2 Others Unspecified Potency n.a. 38895.2 nM PubChem BioAssay data set
NPT2 Others Unspecified Potency n.a. 12197.2 nM PubChem BioAssay data set
NPT2 Others Unspecified Potency n.a. 17228.9 nM PubChem BioAssay data set
NPT2 Others Unspecified Potency n.a. 48966.2 nM PubChem BioAssay data set
NPT2 Others Unspecified Potency n.a. 48557.7 nM PubChem BioAssay data set
NPT2 Others Unspecified Potency n.a. 21872.4 nM PubChem BioAssay data set
NPT2 Others Unspecified Potency n.a. 19493.8 nM PubChem BioAssay data set
NPT2 Others Unspecified Potency n.a. 24336.5 nM PubChem BioAssay data set
NPT2 Others Unspecified Potency n.a. 17373.9 nM PubChem BioAssay data set
NPT2 Others Unspecified Potency n.a. 24541.2 nM PubChem BioAssay data set
NPT74 Individual Protein Proto-oncogene c-JUN Homo sapiens Potency n.a. 13800.6 nM PubChem BioAssay data set
NPT2 Others Unspecified Potency n.a. 968.9 nM PubChem BioAssay data set
NPT2 Others Unspecified Potency n.a. 769.6 nM PubChem BioAssay data set
NPT2 Others Unspecified Potency n.a. 27306 nM PubChem BioAssay data set
NPT2 Others Unspecified Potency n.a. 4855.8 nM PubChem BioAssay data set
NPT2 Others Unspecified Ratio IC50 = 1 n.a. PMID[25906385]
NPT2 Others Unspecified Ratio IC50 = 1.9 n.a. PMID[25906385]
NPT2 Others Unspecified IC50 = 51040 nM PMID[25906385]
NPT32 Organism Mus musculus Mus musculus Blood glucose = 482.4 mg dl-1 PMID[555329]
NPT32 Organism Mus musculus Mus musculus Blood glucose = 503.5 mg dl-1 PMID[555329]
NPT2 Others Unspecified Ratio = 104.4 n.a. PMID[555329]
NPT2 Others Unspecified IC50 > 100000.0 nM PMID[555330]
NPT27 Others Unspecified Therapeutic index = 9.0 n.a. PMID[555331]
NPT2632 Organism Syrian golden hamster Mesocricetus auratus Suppression = 0.0 % PMID[555332]
NPT27 Others Unspecified AUC = 110.0 nM hr ml PMID[555332]
NPT27 Others Unspecified Tmax = 1.0 hr PMID[555332]
NPT2731 Protein Family Monoamine oxidase Homo sapiens Inhibition = 20.7 % PMID[555332]
NPT2731 Protein Family Monoamine oxidase Homo sapiens Inhibition = 28.1 % PMID[555332]
NPT2731 Protein Family Monoamine oxidase Homo sapiens Inhibition = 64.7 % PMID[555332]
NPT2731 Protein Family Monoamine oxidase Homo sapiens Inhibition = 83.5 % PMID[555332]
NPT2731 Protein Family Monoamine oxidase Homo sapiens IC50 = 1600.0 nM PMID[555332]
NPT996 Protein Complex GABA-A receptor; anion channel Homo sapiens Ki = 3019.95 nM PMID[555334]
NPT805 Protein Complex GABA-A receptor; anion channel Rattus norvegicus Ki = 920.0 nM PMID[555335]
NPT805 Protein Complex GABA-A receptor; anion channel Rattus norvegicus GABA ratio = 0.9 n.a. PMID[555335]
NPT27 Others Unspecified Delta Fmax = 94.6 % PMID[555336]
NPT27 Others Unspecified Kd = 13100.0 nM PMID[555336]
NPT27 Others Unspecified Hydrophobicity index = 0.358 n.a. PMID[555336]
NPT35 Others n.a. LogP = 5.7 n.a. PMID[555336]
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 25.0 ug.mL-1 PMID[555338]
NPT1567 Protein Complex DNA gyrase Escherichia coli K-12 IC50 > 500.0 ug.mL-1 PMID[555341]
NPT19 Organism Escherichia coli Escherichia coli MIC > 125.0 ug.mL-1 PMID[555341]
NPT566 Organism Salmonella typhimurium Salmonella enterica subsp. enterica serovar Typhimurium MIC > 125.0 ug.mL-1 PMID[555341]
NPT1521 Organism Stenotrophomonas maltophilia Stenotrophomonas maltophilia MIC > 125.0 ug.mL-1 PMID[555341]
NPT17 Organism Staphylococcus epidermidis Staphylococcus epidermidis MIC > 125.0 ug.mL-1 PMID[555341]
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC > 125.0 ug.mL-1 PMID[555341]
NPT1509 Protein Complex Cyclin-dependent kinase 5/CDK5 activator 1 Homo sapiens IC50 = 3100.0 nM PMID[555342]
NPT1570 Protein Complex Cyclin-dependent kinase 1/cyclin B Homo sapiens IC50 = 7100.0 nM PMID[555342]
NPT1572 Protein Family Glycogen synthase kinase-3 Homo sapiens IC50 = 7200.0 nM PMID[555342]
NPT79 Organism Bacillus subtilis Bacillus subtilis MIC = 50.0 ug.mL-1 PMID[555346]
NPT3935 Organism Bacillus sphaericus Lysinibacillus sphaericus MIC = 25.0 ug.mL-1 PMID[555346]
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 50.0 ug.mL-1 PMID[555346]
NPT720 Organism Enterobacter aerogenes Enterobacter aerogenes MIC = 50.0 ug.mL-1 PMID[555346]
NPT2631 Organism Chromobacterium violaceum Chromobacterium violaceum MIC = 25.0 ug.mL-1 PMID[555346]
NPT6 Organism Plasmodium falciparum Plasmodium falciparum IC50 = 29800.0 nM PMID[555347]
NPT2 Others Unspecified IC50 = 3900.0 nM PMID[555349]
NPT2 Others Unspecified IC50 = 188100.0 nM PMID[555349]
NPT2 Others Unspecified IC50 = 140000.0 nM PMID[555349]
NPT2 Others Unspecified Inhibition = 20.0 % PMID[555349]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. IC25 = 4480.0 uM PMID[555350]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. pIC25 = -3.65 n.a. PMID[555350]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 >= 100000.0 nM PMID[555351]
NPT2 Others Unspecified IC50 = 375550.0 nM PMID[555353]
NPT2 Others Unspecified IC50 = 370670.0 nM PMID[555353]
NPT2 Others Unspecified IC50 = 5.0 ug.mL-1 PMID[555355]
NPT2 Others Unspecified Activity = 11.2 % PMID[555356]
NPT2 Others Unspecified Activity = 75.8 % PMID[555356]
NPT2 Others Unspecified Activity = 77.7 % PMID[555356]
NPT2 Others Unspecified IC50 = 250.0 nM PMID[555356]
NPT2 Others Unspecified ID50 = 12.0 ug ml-1 PMID[555357]
NPT2 Others Unspecified logKi = 0.477 n.a. PMID[555359]
NPT2 Others Unspecified Inhibition = -86.0 % PMID[555360]
NPT2 Others Unspecified Inhibition = -44.0 % PMID[555360]
NPT2 Others Unspecified Inhibition = -14.0 % PMID[555360]
NPT967 Individual Protein Xanthine dehydrogenase Homo sapiens IC50 = 840.0 nM PMID[555364]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. IC50 = 1870.0 nM PMID[555364]
NPT2 Others Unspecified IC50 = 2400.0 nM PMID[555365]
NPT22938 SINGLE PROTEIN Carbonyl reductase [NADPH] 3 Homo sapiens Tm < 2.0 degrees C PMID[555367]
NPT27 Others Unspecified TI = 9.0 n.a. PMID[555369]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 5000.0 nM PMID[555369]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 Activity = 0.5 n.a. PMID[555371]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 Activity = 0.8 n.a. PMID[555371]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 Activity = 1.1 n.a. PMID[555371]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 Activity = 0.25 n.a. PMID[555371]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. EC50 = 74400.0 nM PMID[555372]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. EC50 = 109000.0 nM PMID[555372]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. IC50 = 248200.0 nM PMID[555374]
NPT1 Others Radical scavenging activity ED50 < 100.0 uM PMID[555379]
NPT99 Individual Protein Peroxisome proliferator-activated receptor gamma Homo sapiens FC = 5.6 n.a. PMID[555382]
NPT99 Individual Protein Peroxisome proliferator-activated receptor gamma Homo sapiens FC = 1.3 n.a. PMID[555382]
NPT99 Individual Protein Peroxisome proliferator-activated receptor gamma Homo sapiens FC = 4.0 n.a. PMID[555382]
NPT866 Individual Protein Peroxisome proliferator-activated receptor alpha Homo sapiens FC = 3.4 n.a. PMID[555382]
NPT866 Individual Protein Peroxisome proliferator-activated receptor alpha Homo sapiens FC = 5.3 n.a. PMID[555382]
NPT19 Organism Escherichia coli Escherichia coli MIC > 50.0 ug.mL-1 PMID[555383]
NPT1209 Organism Pseudomonas fluorescens Pseudomonas fluorescens MIC > 50.0 ug.mL-1 PMID[555383]
NPT79 Organism Bacillus subtilis Bacillus subtilis MIC > 50.0 ug.mL-1 PMID[555383]
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC > 50.0 ug.mL-1 PMID[555383]
NPT35 Others n.a. Activity = 0.081 MU PMID[555385]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. Activity = 1.43 MU PMID[555385]
NPT35 Others n.a. Activity = 0.053 MU PMID[555385]
NPT35 Others n.a. Activity = 24.9 mg/L PMID[555385]
NPT2 Others Unspecified Ratio IC50 = 2.6 n.a. PMID[555386]
NPT2 Others Unspecified IC50 = 340000.0 nM PMID[555386]
NPT900 Individual Protein 3-keto-steroid reductase Homo sapiens Inhibition = 6.8 % PMID[555388]
NPT900 Individual Protein 3-keto-steroid reductase Homo sapiens Inhibition = 5.1 % PMID[555388]
NPT711 Individual Protein Aldose reductase Bos taurus IC50 = 7790.0 nM PMID[555391]
NPT35 Others n.a. IC50 = 63540.0 nM PMID[555391]
NPT29 Organism Rattus norvegicus Rattus norvegicus Activity = 0.5 % PMID[555393]
NPT29 Organism Rattus norvegicus Rattus norvegicus Activity = 5.2 % PMID[555393]
NPT29 Organism Rattus norvegicus Rattus norvegicus Activity = 19.6 % PMID[555393]
NPT29 Organism Rattus norvegicus Rattus norvegicus Activity = 7.07 % PMID[555393]
NPT29 Organism Rattus norvegicus Rattus norvegicus Activity = -35.5 % PMID[555393]
NPT29 Organism Rattus norvegicus Rattus norvegicus Activity = -10.41 % PMID[555393]
NPT29 Organism Rattus norvegicus Rattus norvegicus Activity = -9.96 % PMID[555393]
NPT29 Organism Rattus norvegicus Rattus norvegicus Activity = -1.7 % PMID[555393]
NPT29 Organism Rattus norvegicus Rattus norvegicus Activity = -9.42 % PMID[555393]
NPT29 Organism Rattus norvegicus Rattus norvegicus Activity = -17.08 % PMID[555393]
NPT29 Organism Rattus norvegicus Rattus norvegicus Activity = -19.98 % PMID[555393]
NPT29 Organism Rattus norvegicus Rattus norvegicus Activity = -9.27 % PMID[555393]
NPT29 Organism Rattus norvegicus Rattus norvegicus Activity = 17.17 % PMID[555393]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. deltaA = 0.3 n.a. PMID[555394]
NPT566 Organism Salmonella typhimurium Salmonella enterica subsp. enterica serovar Typhimurium pID50 = 6.0 n.a. PMID[555397]
NPT197 Protein-Protein Interaction Menin/Histone-lysine N-methyltransferase MLL Homo sapiens Potency = 31622.8 nM PMID[555399]
NPT2 Others Unspecified Potency = 31622.8 nM PMID[555401]
NPT2 Others Unspecified Potency = 19952.6 nM PMID[555400]
NPT2 Others Unspecified Potency = 25118.9 nM PMID[555399]
NPT93 Individual Protein Survival motor neuron protein Homo sapiens Potency = 28183.8 nM PMID[555401]
NPT93 Individual Protein Survival motor neuron protein Homo sapiens Potency = 14125.4 nM PMID[555402]
NPT93 Individual Protein Survival motor neuron protein Homo sapiens Potency = 3981.1 nM PMID[555400]
NPT94 Individual Protein Aldehyde dehydrogenase 1A1 Homo sapiens Potency = 17782.8 nM PMID[555401]
NPT94 Individual Protein Aldehyde dehydrogenase 1A1 Homo sapiens Potency = 8912.5 nM PMID[555400]
NPT94 Individual Protein Aldehyde dehydrogenase 1A1 Homo sapiens Potency = 15848.9 nM PMID[555402]
NPT94 Individual Protein Aldehyde dehydrogenase 1A1 Homo sapiens Potency = 1584.9 nM PMID[555399]
NPT197 Protein-Protein Interaction Menin/Histone-lysine N-methyltransferase MLL Homo sapiens Potency = 25118.9 nM PMID[555401]
NPT197 Protein-Protein Interaction Menin/Histone-lysine N-methyltransferase MLL Homo sapiens Potency = 31622.8 nM PMID[555400]
NPT2 Others Unspecified Potency = 35481.3 nM PMID[555399]
NPT177 Tissue Aorta Rattus norvegicus IC50 = 75700.0 nM PMID[555403]
NPT177 Tissue Aorta Rattus norvegicus IC50 = 106900.0 nM PMID[555403]
NPT177 Tissue Aorta Rattus norvegicus Emax = 44.75 % PMID[555403]
NPT177 Tissue Aorta Rattus norvegicus Emax = 16.0 % PMID[555403]
NPT2 Others Unspecified Ratio CC50/IC50 = 9.7 n.a. PMID[555404]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. IC50 = 44160.0 nM PMID[555404]
NPT27 Others Unspecified CC50 = 428270.0 nM PMID[555404]
NPT35 Others n.a. IC50 = 63540.0 nM PMID[555405]
NPT668 Individual Protein P-glycoprotein 1 Homo sapiens Kd = 8912.51 nM PMID[555409]
NPT99 Individual Protein Peroxisome proliferator-activated receptor gamma Homo sapiens Potency n.a. 8912.5 nM PMID[555411]
NPT901 Individual Protein UDP-glucuronosyltransferase 1-1 Homo sapiens Activity = 170.0 pm/min/mg PMID[555413]
NPT699 Individual Protein UDP-glucuronosyltransferase 1-10 Homo sapiens Activity = 76.0 pm/min/mg PMID[555413]
NPT902 Individual Protein UDP-glucuronosyltransferase 1A4 Homo sapiens Activity = 0.0 pm/min/mg PMID[555413]
NPT695 Individual Protein UDP-glucuronosyltransferase 1-8 Homo sapiens Activity = 724.0 pm/min/mg PMID[555413]
NPT704 Individual Protein UDP-glucuronosyltransferase 2B15 Homo sapiens Activity = 37.0 pm/min/mg PMID[555413]
NPT947 Individual Protein Carbonic anhydrase I Homo sapiens Ki = 5490.0 nM PMID[555416]
NPT947 Individual Protein Carbonic anhydrase I Homo sapiens Ki = 5420.0 nM PMID[555416]
NPT948 Individual Protein Carbonic anhydrase IX Homo sapiens Ki = 2650.0 nM PMID[555416]
NPT948 Individual Protein Carbonic anhydrase IX Homo sapiens Ki = 2710.0 nM PMID[555416]
NPT949 Individual Protein Carbonic anhydrase XII Homo sapiens Ki = 8960.0 nM PMID[555416]
NPT949 Individual Protein Carbonic anhydrase XII Homo sapiens Ki = 9070.0 nM PMID[555416]
NPT191 Organism Hepatitis C virus Hepatitis C virus Inhibition = 50.97 % PMID[555417]
NPT27 Others Unspecified CC50 > 50000.0 nM PMID[555417]
NPT191 Organism Hepatitis C virus Hepatitis C virus Inhibition = 30.0 % PMID[555417]
NPT2 Others Unspecified Activity = 0.16 mM PMID[555424]
NPT2 Others Unspecified Activity = 0.81 V PMID[555424]
NPT67 Individual Protein Cholinesterase Equus caballus Inhibition = 2.93 % PMID[555425]
NPT992 Organism Entamoeba histolytica Entamoeba histolytica IC50 = 81.0 ug.mL-1 PMID[555427]
NPT1 Others Radical scavenging activity Inhibition = 1.1 % PMID[555429]
NPT1175 Organism Spodoptera litura Spodoptera litura ED50 = 2.5 umol/cm2 PMID[555430]
NPT1175 Organism Spodoptera litura Spodoptera litura ED50 = 635.0 ug PMID[555431]
NPT587 Tissue Liver microsome Rattus norvegicus IC50 = 60.0 ug.mL-1 PMID[555432]
NPT35 Others n.a. IC50 > 67635.0 nM PMID[555439]
NPT22906 PROTEIN COMPLEX Urease subunit alpha/Urease subunit beta Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacterpylori) IC50 = 302000.0 nM PMID[555441]
NPT2 Others Unspecified IC50 = 9590.0 nM PMID[555443]
NPT2 Others Unspecified IC50 = 53000.0 nM PMID[555443]
NPT27 Others Unspecified Activity > 98.0 % PMID[555443]
NPT73 Individual Protein Solute carrier organic anion transporter family member 1B1 Homo sapiens Inhibition = 115.36 % PMID[555445]
NPT72 Individual Protein Solute carrier organic anion transporter family member 1B3 Homo sapiens Inhibition = 129.12 % PMID[555445]
NPT2 Others Unspecified Ratio IC50 = 1.5 n.a. PMID[555446]
NPT89 Individual Protein Seed lipoxygenase-1 Glycine max Ki = 19400.0 nM PMID[555447]
NPT89 Individual Protein Seed lipoxygenase-1 Glycine max Vmax = 0.005 uM PMID[555447]
NPT89 Individual Protein Seed lipoxygenase-1 Glycine max Km = 55020.0 nM PMID[555447]
NPT89 Individual Protein Seed lipoxygenase-1 Glycine max Vmax = 0.006 uM PMID[555447]
NPT89 Individual Protein Seed lipoxygenase-1 Glycine max Km = 70960.0 nM PMID[555447]
NPT2 Others Unspecified IC50 = 77730.0 nM PMID[555448]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. Potency n.a. 11875.4 nM PMID[555451]
NPT2 Others Unspecified Potency n.a. 12589.3 nM PMID[555437]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. Potency n.a. 66.8 nM PMID[555451]
NPT610 Others Molecular identity unknown Potency n.a. 50118.7 nM PMID[555411]
NPT2 Others Unspecified Potency n.a. 3548.1 nM PMID[555438]
NPT2 Others Unspecified Potency n.a. 5011.9 nM PMID[555437]
NPT2 Others Unspecified Potency n.a. 3548.1 nM PMID[555440]
NPT2 Others Unspecified Potency n.a. 2238.7 nM PMID[555402]
NPT2 Others Unspecified Potency n.a. 28183.8 nM PMID[555438]
NPT2 Others Unspecified Potency n.a. 11220.2 nM PMID[555437]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. Potency n.a. 10583.9 nM PMID[555451]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. Potency n.a. 13324.4 nM PMID[555451]
NPT2 Others Unspecified Potency n.a. 2511.9 nM PMID[555402]
NPT2 Others Unspecified Potency n.a. 3162.3 nM PMID[555438]
NPT2 Others Unspecified Potency n.a. 5623.4 nM PMID[555437]
NPT2 Others Unspecified Potency n.a. 3162.3 nM PMID[555440]
NPT2 Others Unspecified Kapp = 759.0 /M PMID[555452]
NPT2 Others Unspecified Kapp = 532.0 /M PMID[555452]
NPT21750 LIPID Lipid bilayer n.a. T = 31.0 degrees C PMID[555452]
NPT21750 LIPID Lipid bilayer n.a. T = 30.4 degrees C PMID[555452]
NPT21750 LIPID Lipid bilayer n.a. T = 30.5 degrees C PMID[555452]
NPT21750 LIPID Lipid bilayer n.a. T = 31.6 degrees C PMID[555452]
NPT21750 LIPID Lipid bilayer n.a. Tm = 40.6 degrees C PMID[555452]
NPT21750 LIPID Lipid bilayer n.a. Tm = 39.8 degrees C PMID[555452]
NPT21750 LIPID Lipid bilayer n.a. Tm = 39.9 degrees C PMID[555452]
NPT21750 LIPID Lipid bilayer n.a. Tm = 40.1 degrees C PMID[555452]
NPT1 Others Radical scavenging activity IC50 = 20.4 ug.mL-1 PMID[555452]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 = 13.4 ug.mL-1 PMID[555453]
NPT27 Others Unspecified Ratio CC50/EC50 = 8.0 n.a. PMID[555453]
NPT35 Others n.a. LogD7.4 n.a. 3.83 n.a. PMID[555454]
NPT2 Others Unspecified Potency n.a. 1258.9 nM PMID[555438]
NPT2 Others Unspecified Potency n.a. 3162.3 nM PMID[555412]
NPT2 Others Unspecified Potency n.a. 1584.9 nM PMID[555437]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. IC50 = 49660.0 nM PMID[555456]
NPT23294 CELL-LINE C13 n.a. Ratio IC50 = 1.7 n.a. PMID[555456]
NPT23294 CELL-LINE C13 n.a. Ratio IC50 = 1.9 n.a. PMID[555456]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. IC50 = 54270.0 nM PMID[555456]
NPT2 Others Unspecified Inhibition = 5.0 % PMID[555457]
NPT947 Individual Protein Carbonic anhydrase I Homo sapiens Ki > 10000.0 nM PMID[555460]
NPT955 Individual Protein Carbonic anhydrase VII Homo sapiens Ki = 171.41 nM PMID[555460]
NPT949 Individual Protein Carbonic anhydrase XII Homo sapiens Ki = 34.7 nM PMID[555460]
NPT861 Individual Protein Isocitrate dehydrogenase [NADP] cytoplasmic Homo sapiens Activity = 96.7 % PMID[555461]
NPT861 Individual Protein Isocitrate dehydrogenase [NADP] cytoplasmic Homo sapiens Activity = 97.6 % PMID[555461]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. IC50 = 18620.0 nM PMID[555463]
NPT27 Others Unspecified IC50 > 40000.0 nM PMID[555463]
NPT27 Others Unspecified IC50 > 100000.0 nM PMID[555464]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. Activity < 50.0 % PMID[555465]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. EC50 = 15890.0 nM PMID[555467]
NPT5898 Organism Taenia crassiceps Taenia crassiceps IC50 = 80000.0 nM PMID[555469]
NPT20632 ORGANISM Chikungunya virus Chikungunya virus IC50 = 22500.0 nM PMID[555475]
NPT2 Others Unspecified IC50 = 28300.0 nM PMID[555478]
NPT2 Others Unspecified IC50 = 35800.0 nM PMID[555478]
NPT20555 ORGANISM SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2 Inhibition = -3.51 % PMID[555479]
NPT22915 PROTEIN FAMILY Casein kinase 2 Homo sapiens IC50 = 9000.0 nM PMID[555483]
NPT2 Others Unspecified Inhibition = 40.0 % PMID[555484]
NPT2 Others Unspecified Inhibition = 95.4 % PMID[555485]
NPT2 Others Unspecified IC50 = 4900.0 nM PMID[555485]
NPT471 Organism Trypanosoma brucei brucei Trypanosoma brucei brucei IC50 < 30000.0 nM PMID[555486]
NPT20556 SINGLE PROTEIN Replicase polyprotein 1ab Severe acute respiratory syndrome coronavirus 2 Inhibition = -6.831 % PMID[555488]
NPT20555 ORGANISM SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2 Inhibition = -0.2 % PMID[555489]
NPT20555 ORGANISM SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2 IC50 > 20000.0 nM PMID[555493]
NPT20555 ORGANISM SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2 IC50 > 19952.62 nM PMID[555493]

☑ Note for Activity Records:
☉ The quantitative biological activities were primarily integrated from ChEMBL (Version-30) database and were also directly collected from PubMed literature. PubMed PMID was provided as the reference link for each activity record.

  Chemically structural similarity: I. Similar Active Natural Products in NPASS

Top-200 similar NPs were calculated against the active-NP-set (includes 4,3285 NPs with experimentally-derived bioactivity available in NPASS)

Similarity level is defined by Tanimoto coefficient (Tc) between two molecules. Tc lies between [0, 1] where '1' indicates the highest similarity. What is Tanimoto coefficient

●  The left chart: Distribution of similarity level between NPC78540 and all remaining natural products in the NPASS database.
●  The right table: Most similar natural products (Tc>=0.56 or Top200).

Similarity Score Similarity Level Natural Product ID
1.0 High Similarity NPC50898
1.0 High Similarity NPC274121
1.0 High Similarity NPC213216
0.9922 High Similarity NPC172262
0.9844 High Similarity NPC57601
0.9843 High Similarity NPC113006
0.9769 High Similarity NPC281917
0.9769 High Similarity NPC231772
0.9769 High Similarity NPC13408
0.9769 High Similarity NPC116775
0.9769 High Similarity NPC127447
0.9769 High Similarity NPC187432
0.9769 High Similarity NPC194281
0.9769 High Similarity NPC29353
0.9769 High Similarity NPC47815
0.9769 High Similarity NPC124784
0.9769 High Similarity NPC473887
0.9769 High Similarity NPC256042
0.9769 High Similarity NPC216361
0.9769 High Similarity NPC234133
0.9695 High Similarity NPC299379
0.9695 High Similarity NPC266597
0.9695 High Similarity NPC250266
0.9692 High Similarity NPC239495
0.9692 High Similarity NPC9985
0.9621 High Similarity NPC201395
0.9615 High Similarity NPC248872
0.9609 High Similarity NPC5515
0.9609 High Similarity NPC270369
0.9609 High Similarity NPC137264
0.9606 High Similarity NPC197425
0.9549 High Similarity NPC216978
0.9549 High Similarity NPC18260
0.9549 High Similarity NPC152042
0.9549 High Similarity NPC55018
0.9549 High Similarity NPC301217
0.9549 High Similarity NPC303633
0.9549 High Similarity NPC143799
0.9549 High Similarity NPC220062
0.9549 High Similarity NPC241838
0.9549 High Similarity NPC78913
0.9549 High Similarity NPC96565
0.9545 High Similarity NPC295261
0.9545 High Similarity NPC287246
0.9545 High Similarity NPC107586
0.9545 High Similarity NPC290291
0.9545 High Similarity NPC32441
0.9545 High Similarity NPC275055
0.9545 High Similarity NPC228661
0.9545 High Similarity NPC79943
0.9545 High Similarity NPC12296
0.9545 High Similarity NPC296490
0.9545 High Similarity NPC13768
0.9545 High Similarity NPC243083
0.9535 High Similarity NPC31872
0.9535 High Similarity NPC473584
0.9535 High Similarity NPC475589
0.9531 High Similarity NPC39753
0.9531 High Similarity NPC115998
0.9478 High Similarity NPC59951
0.9478 High Similarity NPC103342
0.9478 High Similarity NPC103904
0.9478 High Similarity NPC184536
0.9478 High Similarity NPC146679
0.9478 High Similarity NPC159275
0.9478 High Similarity NPC281207
0.9478 High Similarity NPC269652
0.9478 High Similarity NPC261227
0.9478 High Similarity NPC241100
0.9478 High Similarity NPC270883
0.9478 High Similarity NPC230285
0.9478 High Similarity NPC172986
0.9474 High Similarity NPC472460
0.9474 High Similarity NPC99333
0.9474 High Similarity NPC118813
0.9474 High Similarity NPC147686
0.9474 High Similarity NPC280284
0.9474 High Similarity NPC188947
0.9474 High Similarity NPC329225
0.9462 High Similarity NPC25937
0.9462 High Similarity NPC10971
0.9462 High Similarity NPC128216
0.9407 High Similarity NPC147688
0.9407 High Similarity NPC136840
0.9407 High Similarity NPC282300
0.9407 High Similarity NPC262094
0.9407 High Similarity NPC90582
0.9407 High Similarity NPC156590
0.9407 High Similarity NPC64908
0.9407 High Similarity NPC14871
0.9407 High Similarity NPC110969
0.9407 High Similarity NPC118840
0.9407 High Similarity NPC205006
0.9403 High Similarity NPC222342
0.9403 High Similarity NPC150648
0.9403 High Similarity NPC53181
0.9403 High Similarity NPC225153
0.9403 High Similarity NPC20709
0.9403 High Similarity NPC316480
0.9403 High Similarity NPC217186
0.9403 High Similarity NPC261234
0.9403 High Similarity NPC265871
0.9403 High Similarity NPC274784
0.9403 High Similarity NPC310135
0.9403 High Similarity NPC329203
0.9398 High Similarity NPC254841
0.9398 High Similarity NPC476480
0.9398 High Similarity NPC160972
0.9398 High Similarity NPC84585
0.9398 High Similarity NPC188879
0.9394 High Similarity NPC39426
0.9394 High Similarity NPC234560
0.9389 High Similarity NPC93756
0.9389 High Similarity NPC108113
0.9389 High Similarity NPC223457
0.9385 High Similarity NPC278556
0.9338 High Similarity NPC299080
0.9338 High Similarity NPC214236
0.9338 High Similarity NPC11561
0.9338 High Similarity NPC473042
0.9338 High Similarity NPC78803
0.9338 High Similarity NPC59739
0.9338 High Similarity NPC200694
0.9338 High Similarity NPC62840
0.9338 High Similarity NPC293852
0.9338 High Similarity NPC226636
0.9338 High Similarity NPC217083
0.9333 High Similarity NPC6407
0.9333 High Similarity NPC129853
0.9333 High Similarity NPC475680
0.9333 High Similarity NPC110228
0.9333 High Similarity NPC150522
0.9333 High Similarity NPC69769
0.9333 High Similarity NPC235239
0.9333 High Similarity NPC76445
0.9333 High Similarity NPC284550
0.9333 High Similarity NPC305355
0.9333 High Similarity NPC188243
0.9328 High Similarity NPC124269
0.9328 High Similarity NPC276905
0.9323 High Similarity NPC240593
0.9323 High Similarity NPC87545
0.9323 High Similarity NPC235428
0.9318 High Similarity NPC125920
0.9313 High Similarity NPC129132
0.9313 High Similarity NPC87231
0.9313 High Similarity NPC101294
0.9313 High Similarity NPC205468
0.9313 High Similarity NPC212631
0.9313 High Similarity NPC473655
0.9313 High Similarity NPC257756
0.9297 High Similarity NPC22783
0.927 High Similarity NPC470216
0.927 High Similarity NPC293053
0.927 High Similarity NPC9117
0.927 High Similarity NPC219915
0.927 High Similarity NPC24821
0.927 High Similarity NPC279121
0.927 High Similarity NPC190637
0.927 High Similarity NPC11700
0.927 High Similarity NPC38219
0.927 High Similarity NPC212932
0.9265 High Similarity NPC312391
0.9265 High Similarity NPC3188
0.9265 High Similarity NPC324386
0.9265 High Similarity NPC4743
0.9265 High Similarity NPC213322
0.9265 High Similarity NPC103362
0.9259 High Similarity NPC140890
0.9254 High Similarity NPC303644
0.9254 High Similarity NPC162680
0.9254 High Similarity NPC181124
0.9254 High Similarity NPC116632
0.9254 High Similarity NPC209560
0.9254 High Similarity NPC212767
0.9254 High Similarity NPC294409
0.9254 High Similarity NPC7013
0.9248 High Similarity NPC151113
0.9248 High Similarity NPC60667
0.9242 High Similarity NPC294593
0.9242 High Similarity NPC159623
0.9242 High Similarity NPC337373
0.9242 High Similarity NPC312318
0.9242 High Similarity NPC472365
0.9242 High Similarity NPC204960
0.9242 High Similarity NPC242294
0.9242 High Similarity NPC82225
0.9242 High Similarity NPC175098
0.9242 High Similarity NPC56031
0.9242 High Similarity NPC144051
0.9242 High Similarity NPC20560
0.9242 High Similarity NPC28753
0.9242 High Similarity NPC18877
0.9242 High Similarity NPC263670
0.9242 High Similarity NPC192304
0.9242 High Similarity NPC188646
0.9242 High Similarity NPC139813
0.9237 High Similarity NPC308037
0.9237 High Similarity NPC64359
0.9237 High Similarity NPC284424

  Chemically structural similarity: II. Similar Clinical/Approved Drugs

Similarity level is defined by Tanimoto coefficient (Tc) between two molecules.

●  The left chart: Distribution of similarity level between NPC78540 and all drugs/candidates.
●  The right table: Most similar clinical/approved drugs (Tc>=0.56 or Top200).

Similarity Score Similarity Level Drug ID Developmental Stage
0.9545 High Similarity NPD1552 Clinical (unspecified phase)
0.9545 High Similarity NPD1550 Clinical (unspecified phase)
0.9474 High Similarity NPD1549 Phase 2
0.9394 High Similarity NPD1510 Phase 2
0.927 High Similarity NPD1511 Approved
0.9237 High Similarity NPD1240 Approved
0.9203 High Similarity NPD4378 Clinical (unspecified phase)
0.9137 High Similarity NPD1512 Approved
0.9098 High Similarity NPD1607 Approved
0.9065 High Similarity NPD7410 Clinical (unspecified phase)
0.8897 High Similarity NPD2796 Approved
0.8777 High Similarity NPD3750 Approved
0.8699 High Similarity NPD2801 Approved
0.8633 High Similarity NPD970 Clinical (unspecified phase)
0.863 High Similarity NPD1934 Approved
0.8623 High Similarity NPD1551 Phase 2
0.8621 High Similarity NPD4380 Phase 2
0.8592 High Similarity NPD6799 Approved
0.8571 High Similarity NPD2393 Clinical (unspecified phase)
0.8562 High Similarity NPD7411 Suspended
0.8561 High Similarity NPD1203 Approved
0.8523 High Similarity NPD4381 Clinical (unspecified phase)
0.8514 High Similarity NPD8443 Clinical (unspecified phase)
0.8417 Intermediate Similarity NPD3748 Approved
0.84 Intermediate Similarity NPD3749 Approved
0.84 Intermediate Similarity NPD7075 Discontinued
0.8382 Intermediate Similarity NPD6859 Clinical (unspecified phase)
0.8378 Intermediate Similarity NPD6801 Discontinued
0.8372 Intermediate Similarity NPD1548 Phase 1
0.8333 Intermediate Similarity NPD3882 Suspended
0.8322 Intermediate Similarity NPD7096 Clinical (unspecified phase)
0.8322 Intermediate Similarity NPD7819 Suspended
0.831 Intermediate Similarity NPD1243 Approved
0.831 Intermediate Similarity NPD2800 Approved
0.8288 Intermediate Similarity NPD5403 Approved
0.8276 Intermediate Similarity NPD5401 Approved
0.8267 Intermediate Similarity NPD3817 Phase 2
0.8258 Intermediate Similarity NPD422 Phase 1
0.8243 Intermediate Similarity NPD6599 Discontinued
0.8195 Intermediate Similarity NPD9717 Approved
0.8182 Intermediate Similarity NPD7421 Clinical (unspecified phase)
0.8169 Intermediate Similarity NPD2344 Approved
0.8138 Intermediate Similarity NPD643 Clinical (unspecified phase)
0.8129 Intermediate Similarity NPD943 Approved
0.8125 Intermediate Similarity NPD1878 Clinical (unspecified phase)
0.812 Intermediate Similarity NPD1547 Clinical (unspecified phase)
0.8116 Intermediate Similarity NPD2313 Discontinued
0.8092 Intermediate Similarity NPD7768 Phase 2
0.8089 Intermediate Similarity NPD3818 Discontinued
0.8077 Intermediate Similarity NPD6167 Clinical (unspecified phase)
0.8077 Intermediate Similarity NPD6168 Clinical (unspecified phase)
0.8077 Intermediate Similarity NPD7852 Clinical (unspecified phase)
0.8077 Intermediate Similarity NPD6166 Phase 2
0.8074 Intermediate Similarity NPD3225 Approved
0.8041 Intermediate Similarity NPD920 Approved
0.8038 Intermediate Similarity NPD7804 Clinical (unspecified phase)
0.8038 Intermediate Similarity NPD7054 Approved
0.8027 Intermediate Similarity NPD642 Clinical (unspecified phase)
0.8014 Intermediate Similarity NPD6651 Approved
0.8 Intermediate Similarity NPD6959 Discontinued
0.7987 Intermediate Similarity NPD7472 Approved
0.7986 Intermediate Similarity NPD3268 Approved
0.7985 Intermediate Similarity NPD1610 Phase 2
0.7945 Intermediate Similarity NPD2309 Approved
0.7937 Intermediate Similarity NPD6797 Phase 2
0.7908 Intermediate Similarity NPD5402 Approved
0.7902 Intermediate Similarity NPD2799 Discontinued
0.7902 Intermediate Similarity NPD1509 Clinical (unspecified phase)
0.7888 Intermediate Similarity NPD7251 Discontinued
0.7883 Intermediate Similarity NPD2797 Approved
0.7875 Intermediate Similarity NPD7074 Phase 3
0.7857 Intermediate Similarity NPD4868 Clinical (unspecified phase)
0.7857 Intermediate Similarity NPD1296 Phase 2
0.7847 Intermediate Similarity NPD2935 Discontinued
0.7847 Intermediate Similarity NPD6100 Approved
0.7847 Intermediate Similarity NPD6099 Approved
0.7842 Intermediate Similarity NPD6832 Phase 2
0.784 Intermediate Similarity NPD4338 Clinical (unspecified phase)
0.784 Intermediate Similarity NPD4419 Clinical (unspecified phase)
0.784 Intermediate Similarity NPD7808 Phase 3
0.7826 Intermediate Similarity NPD2798 Approved
0.7778 Intermediate Similarity NPD4308 Phase 3
0.7778 Intermediate Similarity NPD7033 Discontinued
0.7754 Intermediate Similarity NPD3267 Approved
0.7754 Intermediate Similarity NPD3266 Approved
0.7727 Intermediate Similarity NPD1465 Phase 2
0.7722 Intermediate Similarity NPD6232 Discontinued
0.7716 Intermediate Similarity NPD5953 Discontinued
0.7714 Intermediate Similarity NPD4908 Phase 1
0.7714 Intermediate Similarity NPD1529 Clinical (unspecified phase)
0.7707 Intermediate Similarity NPD5494 Approved
0.7702 Intermediate Similarity NPD7286 Phase 2
0.7697 Intermediate Similarity NPD3226 Approved
0.7688 Intermediate Similarity NPD7473 Discontinued
0.7687 Intermediate Similarity NPD2654 Approved
0.7687 Intermediate Similarity NPD9545 Approved
0.7677 Intermediate Similarity NPD4288 Approved
0.7669 Intermediate Similarity NPD9493 Approved
0.7667 Intermediate Similarity NPD2533 Approved
0.7667 Intermediate Similarity NPD2534 Approved
0.7667 Intermediate Similarity NPD2532 Approved
0.7664 Intermediate Similarity NPD1608 Approved
0.7664 Intermediate Similarity NPD1481 Phase 2
0.7643 Intermediate Similarity NPD919 Approved
0.7643 Intermediate Similarity NPD1530 Clinical (unspecified phase)
0.7635 Intermediate Similarity NPD4628 Phase 3
0.7606 Intermediate Similarity NPD411 Approved
0.7606 Intermediate Similarity NPD4907 Clinical (unspecified phase)
0.7591 Intermediate Similarity NPD1201 Approved
0.7591 Intermediate Similarity NPD1535 Discovery
0.7576 Intermediate Similarity NPD1241 Discontinued
0.7569 Intermediate Similarity NPD447 Suspended
0.7569 Intermediate Similarity NPD1933 Approved
0.7561 Intermediate Similarity NPD6559 Discontinued
0.7551 Intermediate Similarity NPD2346 Discontinued
0.7547 Intermediate Similarity NPD1247 Approved
0.7534 Intermediate Similarity NPD651 Clinical (unspecified phase)
0.7517 Intermediate Similarity NPD6398 Clinical (unspecified phase)
0.75 Intermediate Similarity NPD1470 Approved
0.75 Intermediate Similarity NPD1612 Clinical (unspecified phase)
0.75 Intermediate Similarity NPD4307 Phase 2
0.75 Intermediate Similarity NPD1613 Approved
0.7483 Intermediate Similarity NPD3764 Approved
0.7483 Intermediate Similarity NPD7390 Discontinued
0.7465 Intermediate Similarity NPD1008 Clinical (unspecified phase)
0.7453 Intermediate Similarity NPD3926 Phase 2
0.7448 Intermediate Similarity NPD230 Phase 1
0.7448 Intermediate Similarity NPD1899 Clinical (unspecified phase)
0.7447 Intermediate Similarity NPD1019 Discontinued
0.7445 Intermediate Similarity NPD17 Approved
0.741 Intermediate Similarity NPD3972 Approved
0.7394 Intermediate Similarity NPD7993 Clinical (unspecified phase)
0.7384 Intermediate Similarity NPD4363 Phase 3
0.7384 Intermediate Similarity NPD4360 Phase 2
0.7378 Intermediate Similarity NPD5844 Phase 1
0.7376 Intermediate Similarity NPD1164 Approved
0.7353 Intermediate Similarity NPD4287 Approved
0.7342 Intermediate Similarity NPD2296 Approved
0.7341 Intermediate Similarity NPD4361 Phase 2
0.7341 Intermediate Similarity NPD4362 Clinical (unspecified phase)
0.7338 Intermediate Similarity NPD6980 Clinical (unspecified phase)
0.7333 Intermediate Similarity NPD1729 Discontinued
0.7329 Intermediate Similarity NPD5124 Phase 1
0.7329 Intermediate Similarity NPD5123 Clinical (unspecified phase)
0.7328 Intermediate Similarity NPD74 Approved
0.7328 Intermediate Similarity NPD9266 Approved
0.732 Intermediate Similarity NPD7004 Clinical (unspecified phase)
0.7315 Intermediate Similarity NPD1471 Phase 3
0.7299 Intermediate Similarity NPD1894 Discontinued
0.7299 Intermediate Similarity NPD8090 Clinical (unspecified phase)
0.7292 Intermediate Similarity NPD4625 Phase 3
0.7261 Intermediate Similarity NPD7615 Clinical (unspecified phase)
0.7252 Intermediate Similarity NPD9263 Approved
0.7252 Intermediate Similarity NPD9265 Clinical (unspecified phase)
0.7252 Intermediate Similarity NPD9264 Approved
0.7252 Intermediate Similarity NPD9267 Approved
0.7241 Intermediate Similarity NPD6798 Discontinued
0.7237 Intermediate Similarity NPD2354 Approved
0.7234 Intermediate Similarity NPD4749 Approved
0.7219 Intermediate Similarity NPD1652 Phase 2
0.7212 Intermediate Similarity NPD3751 Discontinued
0.7195 Intermediate Similarity NPD7784 Clinical (unspecified phase)
0.7153 Intermediate Similarity NPD405 Clinical (unspecified phase)
0.7143 Intermediate Similarity NPD6143 Clinical (unspecified phase)
0.7143 Intermediate Similarity NPD6104 Discontinued
0.7133 Intermediate Similarity NPD5408 Approved
0.7133 Intermediate Similarity NPD5406 Approved
0.7133 Intermediate Similarity NPD5404 Approved
0.7133 Intermediate Similarity NPD5405 Approved
0.7108 Intermediate Similarity NPD5940 Clinical (unspecified phase)
0.7107 Intermediate Similarity NPD6844 Discontinued
0.7089 Intermediate Similarity NPD6585 Discontinued
0.7086 Intermediate Similarity NPD2355 Clinical (unspecified phase)
0.7086 Intermediate Similarity NPD2353 Approved
0.7078 Intermediate Similarity NPD7440 Discontinued
0.7075 Intermediate Similarity NPD6233 Phase 2
0.7073 Intermediate Similarity NPD3787 Discontinued
0.7073 Intermediate Similarity NPD5711 Approved
0.7073 Intermediate Similarity NPD5710 Approved
0.7063 Intermediate Similarity NPD1876 Approved
0.7045 Intermediate Similarity NPD968 Approved
0.7044 Intermediate Similarity NPD5890 Approved
0.7044 Intermediate Similarity NPD5889 Approved
0.7042 Intermediate Similarity NPD9269 Phase 2
0.7037 Intermediate Similarity NPD6971 Discontinued
0.7034 Intermediate Similarity NPD2861 Phase 2
0.7034 Intermediate Similarity NPD9494 Approved
0.7032 Intermediate Similarity NPD7212 Phase 2
0.7032 Intermediate Similarity NPD7213 Phase 3
0.7027 Intermediate Similarity NPD3140 Approved
0.7027 Intermediate Similarity NPD3142 Approved
0.7025 Intermediate Similarity NPD5808 Clinical (unspecified phase)
0.7025 Intermediate Similarity NPD7458 Discontinued
0.7012 Intermediate Similarity NPD7199 Phase 2
0.7007 Intermediate Similarity NPD9281 Approved
0.7 Intermediate Similarity NPD940 Approved
0.7 Intermediate Similarity NPD846 Approved
0.7 Intermediate Similarity NPD9268 Approved
0.6988 Remote Similarity NPD2403 Approved
0.6987 Remote Similarity NPD4662 Approved

  Bioactivity similarity: Similar Natural Products in NPASS

Bioactivity similarity was calculated based on bioactivity descriptors of compounds. The bioactivity descriptors were calculated by a recently developed AI algorithm Chemical Checker (CC) [Nature Biotechnology, 38:1087–1096, 2020; Nature Communications, 12:3932, 2021], which evaluated bioactivity similarities at five levels:
☉ A: chemistry similarity;
☉ B: biological targets similarity;
☉ C: networks similarity;
☉ D: cell-based bioactivity similarity;
☉ E: similarity based on clinical data.

Those 5 categories of CC bioactivity descriptors were calculated and then subjected to manifold projection using UMAP algorithm, to project all NPs on a 2-Dimensional space. The current NP was highlighted with a small circle in the 2-D map. Below figures: left-to-right, A-to-E.

A: chemistry similarity
B: biological targets similarity
C: networks similarity
D: cell-based bioactivity similarity
E: similarity based on clinical data