Natural Product Target: Hypoxia-inducible factor 1 alpha

Target ID:   NPT211
Target Name:   Hypoxia-inducible factor 1 alpha
Target Type:   Individual Protein
Organism of Target:   Homo sapiens
Target External ID:   Uniprot_ID:[ Q16665]

  Biological Activities of Natural Products against the Target

Natural Product ID Natural Product Name # Activity Records
NPC190945 Nifedipine 6
NPC215584 Elliptecine 6
NPC290566 4-[(1R)-2-Amino-1-Hydroxyethyl]Phenol 4
NPC46451 Sanguinarium 4
NPC195268 Papaverine 4
NPC248573 Cis-Resveratrol 4
NPC208280 Glyburide 4
NPC50898 Apigenin 4
NPC41717 Fusaric Acid 4
NPC10286 4-[(1R)-1-Hydroxy-2-(Methylamino)Ethyl]Phenol 4
NPC129909 Camptothecin 4
NPC469949 Clofazimine 4
NPC313449 Dequalinium 4
NPC228343 Nordihydroguaiaretic Acid 4
NPC190501 Estrone 4
NPC45124 (+/-)-Moracin P 3
NPC128582 Chaetocin 3
NPC97577 Lovastatin 3
NPC282294 Ethacrynic Acid 3
NPC4665 3,4-Dihydroxyphenylacetic Acid 2
NPC232727 Harmine 2
NPC108957 N-[(7R)-1,2,3,10-Tetramethoxy-9-Oxo-6,7-Dihydro-5H-Benzo[A]Heptalen-7-Yl]Acetamide 2
NPC290449 8-Azaguanine 2
NPC142599 N-[2-(3,4-Dihydroxyphenyl)Ethyl]Acetamide 2
NPC316574 Mesalamine 2
NPC5167 Graveoline 2
NPC26244 Dienestrol 2
NPC109188 Azaribine 2
NPC144956 Methylprednisolone 2
NPC317177 Tretinoin 2
NPC20791 Quercetin 2
NPC68441 Gossypol 2
NPC235077 Triamcinolone 2
NPC113236 (Z)-Piplartine 2
NPC146422 Dopamine 2
NPC39426 Genistein 2
NPC194857 4-Ethyl-3-Methyl-N-[2-[4-[(4-Methylcyclohexyl)Carbamoylsulfamoyl]Phenyl]Ethyl]-5-Oxo-2H-Pyrrole-1-Carboxamide 2
NPC236347 Epinephrine 2
NPC51695 4-[(2R)-2-[(1R,3R,5S)-3,5-Dimethyl-2-Oxocyclohexyl]-2-Hydroxyethyl]Piperidine-2,6-Dione 2
NPC116775 Kaempferol 2
NPC33338 (1S)-1-Methyl-1,2,3,4-Tetrahydroisoquinoline-6,7-Diol 2
NPC16452 Palmitine 2
NPC317651 (2S,3S,4R,5R)-3,4,5,6-Tetrahydroxyoxane-2-Carboxylic Acid 2
NPC471785 Sid11111800 2
NPC76336 Scopoletin 2
NPC237946 Podofilox 2
NPC116961 Loratadine 2
NPC292758 (1R)-2-[(2R,6R)-6-[(2S)-2-Hydroxy-2-Phenylethyl]-1-Methylpiperidin-2-Yl]-1-Phenylethanol 2
NPC319333 2-(Carboxymethylsulfanyl)Acetic Acid 2
NPC196447 (6Ar)-1,10-Dimethoxy-6-Methyl-5,6,6A,7-Tetrahydro-4H-Dibenzo[De,G]Quinoline-2,9-Diol 2
NPC473432 Amsacrine 2
NPC78540 Chrysin 2
NPC241392 (2R)-4-(2-Amino-3-Hydroxyphenyl)-2-Azaniumyl-4-Oxobutanoate 2
NPC1075 (Z)-3-(3,4-Dihydroxyphenyl)Prop-2-Enoic Acid 2
NPC119838 Cantharidin 2
NPC294409 Biochanin 2
NPC160900 (1E,6E)-1,7-Bis(4-Hydroxy-3-Methoxyphenyl)Hepta-1,6-Diene-3,5-Dione 2
NPC322433 Aminohippuric Acid 2
NPC203468 Tryptophan 2
NPC470003 Sid4253497 2
NPC85276 Deoxiepinephrine 2
NPC120671 (6R)-6-[(5R)-6-Methyl-7,8-Dihydro-5H-[1,3]Dioxolo[4,5-G]Isoquinolin-5-Yl]-6H-Furo[3,4-G][1,3]Benzodioxol-8-One 2
NPC294909 Rauwolfia Serpentina 2
NPC18509 Hydrocortisone 2
NPC326651 (3R)-3-Hexadecanoyloxy-4-(Trimethylazaniumyl)Butanoate 2
NPC204932 Catechol 2
NPC471614 Ketoconazole 2
NPC50511 Kinetin 2
NPC88667 Melevodopa 2
NPC252603 Theophylline 2
NPC295531 Oxytetracycline 2
NPC161571 Resveratrol 2
NPC41326 Coumestrol 2
NPC21429 Rutaecarpine 2
NPC254847 Emodin 2
NPC124886 n.a. 2
NPC302950 Hesperetin 2
NPC161593 Levodopa 2
NPC327579 Ganciclovir 2
NPC208553 Paclitaxel 2
NPC476440 Tpck 2
NPC9743 (+)-Epitaxifolin 2
NPC53069 Berberine 2
NPC125039 Silibinin 2
NPC165549 Deguelin 2
NPC212415 Beta-Lapachone 2
NPC269827 (2R,3R,4S,5R)-2-(6-Amino-2-Chloropurin-9-Yl)-5-(Hydroxymethyl)Oxolane-3,4-Diol 2
NPC56109 Ergocristine 2
NPC305039 Hydroxyprogesterone Caproate 2
NPC168027 Corticosterone 2
NPC471593 Sc-560 2
NPC100079 Chelerythrine 2
NPC279121 Luteolin 2
NPC58427 4-[(Z)-2-(3,5-Dihydroxyphenyl)Ethenyl]Benzene-1,2-Diol 2
NPC306843 Boldine 2
NPC169050 (2R)-4-Methoxy-2-[(Z)-2-Phenylethenyl]-2,3-Dihydropyran-6-One 2
NPC470090 Sp-600125 2
NPC100734 Methyl (1S,15R,17S,18S,19R,20R)-6,18-Dimethoxy-17-(3,4,5-Trimethoxybenzoyl)Oxy-1,3,11,12,14,15,16,17,18,19,20,21-Dodecahydroyohimban-19-Carboxylate 2
NPC65517 Hydroquinone 2
NPC133140 Papaverine Hydrochloride 2
NPC307176 Progesterone 2
NPC169749 Myricetin 2
NPC227396 Prostaglandin B1 2
NPC105488 Cycloserine 2
NPC67076 Prostaglandin A2 2
NPC137096 Phenylephrine 2
NPC190184 (2R)-5-Amino-2-Azaniumyl-5-Oxopentanoate 2
NPC107919 Aphidicolin 2
NPC282307 Pomiferin 2
NPC137949 Esculetin 2
NPC37423 [(6As,9R)-7-Methyl-6,6A,8,9-Tetrahydro-4H-Indolo[4,3-Fg]Quinoline-9-Yl]Methanol 2
NPC190334 4-Amino-1-[(2R,3R,4S,5S)-3,4-Dihydroxy-5-(Hydroxymethyl)Oxolan-2-Yl]Pyrimidin-2-One 2
NPC43945 Menadione 2
NPC231772 Acacetin 2
NPC108606 Cathine 2
NPC288089 Rhein 2
NPC141791 2-Phenylethyl (Z)-3-(3,4-Dihydroxyphenyl)Prop-2-Enoate 2
NPC44063 Prednisolone Acetate 2
NPC291548 n.a. 1
NPC70201 4-Aminophenol 1
NPC30655 Moracin P 1
NPC2634 Guggulsterone 1
NPC477425 (1S,6R)-3-methyl-6-[(2S)-4-[(1R,2R,3R,4S)-1,2,4-trimethyl-7-oxabicyclo[2.2.1]heptan-3-yl]butan-2-yl]cyclohex-2-en-1-ol 1
NPC477427 (1R,6R)-3-methyl-6-[(2S)-4-[(1R,2R,3R,4S)-1,2,4-trimethyl-7-oxabicyclo[2.2.1]heptan-3-yl]butan-2-yl]cyclohex-2-en-1-ol 1
NPC123273 4-Nonylphenol 1
NPC477426 (1S,6R)-3-methyl-6-[(2R)-4-[(1R,2R,3R,4S)-1,2,4-trimethyl-7-oxabicyclo[2.2.1]heptan-3-yl]butan-2-yl]cyclohex-2-en-1-ol 1
NPC262615 Deferoxamine 1
NPC304839 (-)-Moracin O 1
NPC66191 Dactinomycin 1
NPC125416 Chlorhexidine 1
NPC220582 Moracin O 1
NPC280026 Lithocholic Acid 1
NPC212369 Puupehenone 1
NPC315216 7,12-Dimethylbenzo[A]Anthracene 1

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