Natural Product Target: Bile acid receptor FXR

Target ID:   NPT540
Target Name:   Bile acid receptor FXR
Target Type:   Individual Protein
Organism of Target:   Homo sapiens
Target External ID:   Uniprot_ID:[ Q96RI1]

  Biological Activities of Natural Products against the Target

Natural Product ID Natural Product Name # Activity Records
NPC34046 Chenodiol 53
NPC2634 Guggulsterone 12
NPC280026 Lithocholic Acid 9
NPC252004 P-Isopentenyloxybenzaldehyde 7
NPC473855 Etrogol Acetate 7
NPC60825 7-O-Methylcryptochinone B 7
NPC473626 Geranyloxyvanillin 7
NPC38079 Etrogol 7
NPC165646 (E)-3-[4-[(2E)-3,7-Dimethylocta-2,6-Dienoxy]-3-Methoxyphenyl]Prop-2-En-1-Ol 7
NPC291189 Valencic Acid 7
NPC291419 7-O-Methylcryptochinone A 7
NPC199023 Nelumol A 7
NPC19242 Collinin 7
NPC9457 Alisol M 23-Acetate 7
NPC470391 Lawsone 2-Isopentenyl Ether 7
NPC281356 7-Prenyloxycoumarin 7
NPC470392 N-Acetyl-O-Isopentenyl-L-Tyrosine 7
NPC180006 Auraptene 7
NPC37858 Boropinic Acid 7
NPC221798 Geranyloxy-P-Benzoic Acid 7
NPC265782 E-Guggulsterone 7
NPC108545 Nelumal A 7
NPC108875 3-(4-Isopentenyloxyphenyl)-1-Propanol 7
NPC188879 4-Hydroxycordoin 7
NPC470393 2-(4-Geranyloxyphenyl)-1-Ethanol 7
NPC180557 Alisol A-23 Acetate 6
NPC307176 Progesterone 5
NPC206614 Tagitinin A 4
NPC88255 Cryptochinone A 4
NPC162071 Tirotundin 4
NPC290971 Dichlorvos 4
NPC136994 Cryptochinone B 4
NPC80089 Cholic Acid 4
NPC315216 7,12-Dimethylbenzo[A]Anthracene 3
NPC173555 Digoxin 3
NPC226941 Colchicine 3
NPC189206 Atractylenolide Ii 3
NPC161423 Testosterone 2
NPC269877 Cholecalciferol 2
NPC288089 Rhein 2
NPC190945 Nifedipine 2
NPC247891 Tauroursodeoxycholate 2
NPC276290 Sarcophine 2
NPC88923 Reserpine 2
NPC63479 Pentachlorophenol 2
NPC65517 Hydroquinone 2
NPC116961 Loratadine 2
NPC469812 Ivermectin 2
NPC50898 Apigenin 2
NPC94167 Riboflavin 2
NPC291548 n.a. 2
NPC39426 Genistein 2
NPC33144 Zearalenone 2
NPC271440 2-Phenylphenol 2
NPC253749 Allethrin 2
NPC66191 Dactinomycin 2
NPC197239 Levothyroxine 2
NPC68441 Gossypol 2
NPC97260 Actein 2
NPC320478 Taurolithocholic Acid 2
NPC94248 Zeranol 2
NPC149571 Raloxifene 2
NPC10636 Atractylenolide Iii 2
NPC283751 Deoxy Cholate 2
NPC185041 Myristyl Alcohol 2
NPC245531 Chlorothalonil 2
NPC160900 (1E,6E)-1,7-Bis(4-Hydroxy-3-Methoxyphenyl)Hepta-1,6-Diene-3,5-Dione 2
NPC110496 12-Epi-O-Deacetyl-19-Deoxyscalarin 1
NPC37493 Acetyl Acetate 1
NPC133995 Taurochenodeoxycholate 1
NPC246956 3-Hydroxylup-20(29)-En-28-Amide 1
NPC12774 Methyl Betulinate 1
NPC211250 2-Methylpropanoyl 2-Methylpropanoate 1
NPC136330 Piperine 1
NPC192744 Betunolic Acid 1
NPC4209 Deoxycholic Acid 1
NPC116775 Kaempferol 1
NPC216630 Palmitic Acid 1
NPC43300 Lupenone 1
NPC28598 Methyl Pentadecanoate 1
NPC471611 Patulin 1
NPC93084 Dioctyl Benzene-1,2-Dicarboxylate 1
NPC193347 Methyltestosterone 1
NPC193484 Methysticin 1
NPC317177 Tretinoin 1
NPC223400 1,3-Dichloropropene 1
NPC138113 Myrcene 1
NPC248970 Acetylcysteine 1
NPC168027 Corticosterone 1
NPC93882 Nonivamide 1
NPC194951 12-Episcalarin 1
NPC118343 Benzyl Benzoate 1
NPC223468 Menthol 1
NPC14917 5-Methyl-2-Propan-2-Ylidenecyclohexan-1-One 1
NPC253703 Cycloheximide 1
NPC171426 Ursodiol 1
NPC142087 (S)-Sargachromenol 1
NPC95034 (R)-Sargachromenol 1
NPC195268 Papaverine 1
NPC119633 Glycochenodeoxycholate 1
NPC317601 Tuberatolide B 1
NPC223675 Dodecyl 2-Methylprop-2-Enoate 1
NPC139891 Coumarin 1
NPC38350 Beta-Elemonic Acid 1
NPC31539 1,4-Dihydroxynaphthalene-2-Carboxylic Acid 1
NPC172066 (E)-3-[(1R,4S,7R,7Ar)-1-Hydroxy-3,7-Dimethyl-2,4,5,6,7,7A-Hexahydro-1H-Inden-4-Yl]-2-Methylprop-2-Enoic Acid 1
NPC95412 Antimycin A 1
NPC292792 Methyleugenol 1
NPC119914 Dibromo(Chloro)Methane 1
NPC317724 2-[2-(2-Methoxyethoxy)Ethoxy]Ethanol 1
NPC224987 4-(Oxiran-2-Yl)-7-Oxabicyclo[4.1.0]Heptane 1
NPC142415 Oleanolic_Acid 1
NPC189075 12-O-Deacetyl-12-Epi-19-Deoxy-22-Hydroxyscalarin 1
NPC254847 Emodin 1
NPC67917 Amphotericin B 1
NPC272426 Sodium Lauryl Sulfate 1
NPC157441 12-O-Deacetyl-12-Epi-19-O-Methylscalarin 1
NPC96835 Phenanthrene 1
NPC293378 Citric Acid 1
NPC123273 4-Nonylphenol 1
NPC320287 Permethrin 1
NPC225539 Furan 1
NPC144682 Butylated Hydroxytoluene 1
NPC47946 Geranyl Acetate 1
NPC256838 3-Aminophenol 1
NPC275539 12-O-Deacetyl-12-Epi-19-Deoxy-21-Hydroxyscalarin 1
NPC12046 12-O-Deacetyl-12-Epi-Scalarin 1
NPC294548 Linolenic Acid 1
NPC200845 Ethyl (9E,12E,15E)-Octadeca-9,12,15-Trienoate 1
NPC125039 Silibinin 1
NPC226066 Retinyl Acetate 1
NPC144939 Allyl Isothiocyanate 1
NPC119481 Archazolid A 1
NPC30583 Platanic Acid 1
NPC70201 4-Aminophenol 1
NPC174048 2,5-Dichlorophenol 1
NPC471614 Ketoconazole 1
NPC301585 Myristic Acid 1
NPC201622 Methyl Dodecanoate 1
NPC125306 Diphenylether 1
NPC321568 (2Z,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-Trimethylcyclohexen-1-Yl)Nona-2,4,6,8-Tetraenal 1
NPC226143 Michler's Ketone 1
NPC147096 Tridecan-1-Ol 1
NPC261831 Oleic Acid 1
NPC72260 Digitoxin 1
NPC178383 Betulin 1
NPC99240 Desmethoxyyangonin 1
NPC2982 1-(4-Tert-Butyl-2,6-Dimethyl-3,5-Dinitrophenyl)Ethanone 1
NPC201844 Dodecanoate 1
NPC125416 Chlorhexidine 1
NPC40394 Uvaol 1
NPC16729 Azadiractin 1
NPC263548 Asiatic Acid 1
NPC75844 Fluorouracil 1
NPC281986 Retinal 1
NPC51700 Ursolic Acid 1
NPC99557 2-Tert-Butyl-6-[(3-Tert-Butyl-2-Hydroxy-5-Methylphenyl)Methyl]-4-Methylphenol 1
NPC306074 2-Tert-Butylphenol 1
NPC203335 Yezoquinolide 1
NPC125549 1-Chloro-4-(4-Chlorophenyl)Sulfonylbenzene 1
NPC323113 Cyromazine 1
NPC24506 Decanol 1
NPC48342 Estradiol 1
NPC264317 Betulinic Acid 1
NPC6848 Betadex 1
NPC282087 Liothyronine 1
NPC477971 [(1R,5bS,11aS,13R,13aS,13bS)-1,13-dihydroxy-8,8,11a,13a-tetramethyl-1,3,5,5a,6,7,7a,9,10,11,11b,12,13,13b-tetradecahydrophenanthro[2,1-e][2]benzofuran-5b-yl]methyl acetate 1
NPC99734 Ethinyl Estradiol 1
NPC307063 Friedeline 1
NPC203719 Vanillin 1
NPC127326 Isosafrole 1
NPC327527 Suvanine's Sodium Salt 1
NPC231063 Arjunolic Acid 1
NPC151648 Tuberatolide A 1
NPC264956 (3-Hydroxy-2,2-Dimethyl-3H-1-Benzofuran-7-Yl) N-Methylcarbamate 1
NPC78540 Chrysin 1
NPC282294 Ethacrynic Acid 1
NPC182840 Nerol 1
NPC477970 (1R,5bR,11aS,13R,13aS,13bS)-1-methoxy-5b,8,8,11a,13a-pentamethyl-1,3,5,5a,6,7,7a,9,10,11,11b,12,13,13b-tetradecahydrophenanthro[2,1-e][2]benzofuran-13-ol 1
NPC204932 Catechol 1
NPC129100 (2R,3R,4R,5S,6R)-3-Amino-6-(Hydroxymethyl)Oxane-2,4,5-Triol 1
NPC329190 Paraoxon 1
NPC27323 4-(2-Methylbutan-2-Yl)Phenol 1
NPC151719 (Z)-Tricos-9-Ene 1
NPC477969 (1R,5bS,11aS,13R,13aS,13bS)-5b-(hydroxymethyl)-8,8,11a,13a-tetramethyl-1,3,5,5a,6,7,7a,9,10,11,11b,12,13,13b-tetradecahydrophenanthro[1,2-g][2]benzofuran-1,13-diol 1
NPC309367 Thiram 1
NPC205213 Triclosan 1
NPC130931 Anthranilic Acid 1
NPC329416 Isotretinoin 1
NPC27765 Alpha-Amyrin 1
NPC266144 Tetradec-1-Ene 1
NPC85493 2-Methoxycarbonylbenzoic Acid 1
NPC286904 Orthocresol 1
NPC477968 [(1R,5bS,11aS,13R,13aS,13bS)-13-acetyloxy-1-hydroxy-8,8,11a,13a-tetramethyl-1,3,5,5a,6,7,7a,9,10,11,11b,12,13,13b-tetradecahydrophenanthro[2,1-e][2]benzofuran-5b-yl]methyl acetate 1
NPC109637 Yangonin 1
NPC311660 Questiomycin B 1
NPC206007 Benzofuran 1
NPC131981 Camphor 1
NPC329427 2'-Epi-Tuberatolide B 1
NPC266539 Dodec-1-Ene 1
NPC85813 Linoleic Acid 1
NPC287231 Isopropyl Palmitate 1
NPC477972 [(1R,5bR,11aS,13R,13aS,13bS)-1-hydroxy-5b,8,8,11a,13a-pentamethyl-1,3,5,5a,6,7,7a,9,10,11,11b,12,13,13b-tetradecahydrophenanthro[2,1-e][2]benzofuran-13-yl] acetate 1

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3. Compound Information: compound related data of all natural products that have available activity against this target;
4. Species Source: species sources that all natural products that have available activity against this target derived from.

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