Natural Product Target: Cytochrome P450 2C19

Target ID:   NPT213
Target Name:   Cytochrome P450 2C19
Target Type:   Individual Protein
Organism of Target:   Homo sapiens
Target External ID:   Uniprot_ID:[ P33261]

  Biological Activities of Natural Products against the Target

Natural Product ID Natural Product Name # Activity Records
NPC471614 Ketoconazole 9
NPC469308 Sb-203580 7
NPC195268 Papaverine 6
NPC119818 (3R)-6,7-Dimethoxy-3-[(5R)-4-Methoxy-6-Methyl-7,8-Dihydro-5H-[1,3]Dioxolo[4,5-G]Isoquinolin-5-Yl]-3H-2-Benzofuran-1-One 6
NPC308885 Zucapsaicin 5
NPC169749 Myricetin 5
NPC70290 1R,9S-Hydrastine 5
NPC473417 Trifluoperazine 5
NPC116961 Loratadine 5
NPC149571 Raloxifene 4
NPC46451 Sanguinarium 4
NPC190945 Nifedipine 4
NPC473206 Diphenyleneiodonium 4
NPC113099 (2S)-2-(Tert-Butylamino)-1-(3-Chlorophenyl)Propan-1-One 4
NPC215584 Elliptecine 3
NPC32441 Naringenin 3
NPC20791 Quercetin 3
NPC218530 Dihydrocapsaicin 3
NPC328267 Fluoxetine 3
NPC194881 n.a. 3
NPC242895 Phloretin 3
NPC50898 Apigenin 3
NPC228343 Nordihydroguaiaretic Acid 3
NPC248573 Cis-Resveratrol 3
NPC172937 Vitamin B2 3
NPC202771 Noscapine 3
NPC471603 Sb-202190 3
NPC116775 Kaempferol 3
NPC39426 Genistein 3
NPC42793 Verapamil 3
NPC302950 Hesperetin 3
NPC120671 (6R)-6-[(5R)-6-Methyl-7,8-Dihydro-5H-[1,3]Dioxolo[4,5-G]Isoquinolin-5-Yl]-6H-Furo[3,4-G][1,3]Benzodioxol-8-One 3
NPC320656 Sertraline 3
NPC148014 n.a. 2
NPC43945 Menadione 2
NPC125416 Chlorhexidine 2
NPC282307 Pomiferin 2
NPC93882 Nonivamide 2
NPC326651 (3R)-3-Hexadecanoyloxy-4-(Trimethylazaniumyl)Butanoate 2
NPC327613 Carcinine 2
NPC95589 Spermine 2
NPC226453 Arginine 2
NPC313618 Oxybenzone 2
NPC165549 Deguelin 2
NPC476440 Tpck 2
NPC226941 Colchicine 2
NPC169050 (2R)-4-Methoxy-2-[(Z)-2-Phenylethenyl]-2,3-Dihydropyran-6-One 2
NPC36836 Nicardipine 2
NPC33320 Methoxsalen 2
NPC5167 Graveoline 2
NPC100079 Chelerythrine 2
NPC129909 Camptothecin 2
NPC476464 Chloroquine 2
NPC68441 Gossypol 2
NPC200085 Naramycin B 2
NPC314968 1-Methyl-1-Nitroso-3-[2,4,5-Trihydroxy-6-(Hydroxymethyl)Oxan-3-Yl]Urea 2
NPC133162 Nortriptyline 2
NPC471615 Pleconaril 2
NPC316574 Mesalamine 2
NPC249797 (13Ar)-3,10-Dimethoxy-6,8,13,13A-Tetrahydro-5H-Isoquinolino[2,1-B]Isoquinoline-2,9-Diol 2
NPC176814 Arctigenin 2
NPC293799 Gs-39783 2
NPC72788 (6S)-6-[(5R)-6-Methyl-7,8-Dihydro-5H-[1,3]Dioxolo[4,5-G]Isoquinolin-5-Yl]-6H-Furo[3,4-G][1,3]Benzodioxol-8-One 2
NPC228932 (2R)-2-Azaniumyl-3-Sulfosulfanylpropanoate 2
NPC316896 Escitalopram 2
NPC138487 n.a. 2
NPC254847 Emodin 2
NPC208280 Glyburide 2
NPC115159 (Z)-1-(2,4-Dihydroxyphenyl)-3-(4-Hydroxyphenyl)Prop-2-En-1-One 2
NPC141791 2-Phenylethyl (Z)-3-(3,4-Dihydroxyphenyl)Prop-2-Enoate 2
NPC294909 Rauwolfia Serpentina 2
NPC229113 Dicumarol 2
NPC471593 Sc-560 2
NPC52764 Letrozole 2
NPC230805 8-Hydroxy-2-Methyl-1H-Quinazolin-4-One 2
NPC146373 Anabasine 2
NPC264293 Khellin 2
NPC298093 Rotenone 2
NPC78540 Chrysin 2
NPC212415 Beta-Lapachone 2
NPC231772 Acacetin 2
NPC318591 Propranolol 2
NPC476483 Vorinostat 2
NPC188341 Oleamide 2
NPC330326 Isoniazid 2
NPC190296 Nb-Acetyltryptamine 2
NPC234560 Daidzein 2
NPC279121 Luteolin 1
NPC190461 n.a. 1
NPC84281 Endo-Atropine 1
NPC213216 5,7-Dihydroxy-2-(2-Hydroxyphenyl)Chromen-4-One 1
NPC308267 n.a. 1
NPC234822 n.a. 1
NPC2989 Warfarin 1
NPC125732 Tyramine 1
NPC235077 Triamcinolone 1
NPC326248 N-Methylhistamine 1
NPC160661 Betonicine 1
NPC141353 1
NPC95162 Fraxetin 1
NPC311219 Aspirin 1
NPC127447 Techtochrysin 1
NPC236070 (2R)-2,5,7,8-Tetramethyl-2-[(4S,8S)-4,8,12-Trimethyltridecyl]-3,4-Dihydrochromen-6-Ol 1
NPC161571 Resveratrol 1
NPC283908 Pimaric Acid 1
NPC191104 Bergamottin 1
NPC13696 5-[(S)-Amino(Carboxy)Methyl]-2-Hydroxybenzoic Acid 1
NPC237946 Podofilox 1
NPC286989 Dexfosfoserine 1
NPC194562 Transtorine 1
NPC96286 Osthole 1
NPC36491 Simvastatin 1
NPC129687 Asarinin 1
NPC239312 Baicalein 1
NPC41719 Karanjin 1
NPC291389 Harmol 1
NPC67917 Amphotericin B 1
NPC99734 Ethinyl Estradiol 1
NPC24019 Oxoglaucine 1
NPC13768 (R)-Pinocembrin 1
NPC329003 Oleoylethanolamide 1
NPC19174 Isoliquiritigenin 1
NPC227622 Erythromycin 1
NPC37496 Glabranin 1
NPC245244 3-[(2R)-Piperidin-2-Yl]Pyridine 1
NPC329567 Levofloxacin 1
NPC292998 7-Methoxy-2-Methyl-3-Phenylchromen-4-One 1
NPC102008 Atorvastatin 1
NPC469812 Ivermectin 1
NPC293454 Carnosic Acid 1
NPC110126 Gramine 1
NPC228785 Mangostin 1
NPC133183 (2S)-2-Amino-5-[[Amino(Dimethylamino)Methylidene]Amino]Pentanoic Acid 1
NPC66191 Dactinomycin 1
NPC207554 Tryptanthrin 1
NPC250266 2-(4-Hydroxyphenyl)-7-Methoxychromen-4-One 1
NPC178134 Ellagic Acid 1
NPC294409 Biochanin 1
NPC51146 Psoralen 1
NPC73020 Hydrastine 1
NPC229084 (1Z,6Z)-1,7-Bis(4-Hydroxy-3-Methoxyphenyl)Hepta-1,6-Diene-3,5-Dione 1
NPC316910 Celecoxib 1
NPC139813 (E)-1-(2-Hydroxy-4-Methoxyphenyl)-3-(4-Methoxyphenyl)Prop-2-En-1-One 1
NPC256849 Caffeine 1
NPC20322 Aminopyrine 1
NPC471785 Sid11111800 1
NPC74539 Bergapten 1
NPC208793 Aspartic Acid 1
NPC116632 4',7-Dimethoxy-5-Hydroxygenistein 1
NPC317177 Tretinoin 1
NPC143168 Embelin 1
NPC264166 Quinidine 1
NPC185903 L-Carnosine 1
NPC34770 Skimmianine 1
NPC76327 Acetaminophen 1
NPC209560 Formononetin 1
NPC187432 Galangin 1
NPC3531 Valproic Acid 1
NPC146703 Benzamide 1
NPC266597 Pratol 1
NPC300059 Taurine 1
NPC59035 Menthofuran 1
NPC79496 n.a. 1
NPC212631 (E)-1-(2,6-Dihydroxy-4-Methoxyphenyl)-3-Phenylprop-2-En-1-One 1
NPC231884 (S)-Verapamil 1
NPC320242 Metoprolol 1
NPC147000 Pseudoephedrine 1
NPC278175 (Z)-1-[6-[(3-Acetyl-2,4,6-Trihydroxy-5-Methylphenyl)Methyl]-5,7-Dihydroxy-2,2-Dimethylchromen-8-Yl]-3-Phenylprop-2-En-1-One 1
NPC66083 Haplamine 1
NPC7491 n.a. 1
NPC212794 Isoboldine 1
NPC303581 n.a. 1

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4. Species Source: species sources that all natural products that have available activity against this target derived from.

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