Natural Product Target: MAP kinase ERK2

Target ID:   NPT282
Target Name:   MAP kinase ERK2
Target Type:   Individual Protein
Organism of Target:   Homo sapiens
Target External ID:   Uniprot_ID:[ P28482]

  Biological Activities of Natural Products against the Target

Natural Product ID Natural Product Name # Activity Records
NPC98371 Staurosporine 14
NPC469308 Sb-203580 10
NPC471603 Sb-202190 7
NPC470090 Sp-600125 5
NPC469975 Seliciclib 5
NPC285829 Plumbagin 4
NPC471614 Ketoconazole 4
NPC56271 Gefitinib 4
NPC100079 Chelerythrine 3
NPC46451 Sanguinarium 3
NPC103540 Danthron 3
NPC317237 Haematoxylin 3
NPC20791 Quercetin 3
NPC238629 Purpurin 3
NPC242895 Phloretin 3
NPC68441 Gossypol 3
NPC245531 Chlorothalonil 3
NPC294226 Athraquinones A 3
NPC476118 Sunitinib 3
NPC201731 Osajin 3
NPC254847 Emodin 3
NPC147418 Quinalizarin 3
NPC63370 Nicardipine Hydrochloride 3
NPC180504 A-443654 3
NPC131887 Ro-316233 3
NPC133140 Papaverine Hydrochloride 3
NPC471611 Patulin 2
NPC282307 Pomiferin 2
NPC85233 Nobiletin 2
NPC316325 Herbimycin 2
NPC212415 Beta-Lapachone 2
NPC160900 (1E,6E)-1,7-Bis(4-Hydroxy-3-Methoxyphenyl)Hepta-1,6-Diene-3,5-Dione 2
NPC162268 Debromohymenialdisine 2
NPC51443 Fisetin 2
NPC39426 Genistein 2
NPC33144 Zearalenone 2
NPC333139 Wortmannin 2
NPC190945 Nifedipine 2
NPC264938 Alvocidib 2
NPC332382 Metronidazole 2
NPC471579 2
NPC477530 Mundulone 2
NPC119838 Cantharidin 2
NPC289432 1,6-Dimethyl-1,2-Dihydronaphtho[1,2-G][1]Benzofuran-10,11-Dione 2
NPC290550 Emodic Acid 2
NPC136002 Fascaplysin 2
NPC225710 Gallic Acid 2
NPC269827 (2R,3R,4S,5R)-2-(6-Amino-2-Chloropurin-9-Yl)-5-(Hydroxymethyl)Oxolane-3,4-Diol 2
NPC184932 Hymenialdisine 2
NPC55422 n.a. 2
NPC195268 Papaverine 2
NPC73411 (2E,5S,6S,8Z,11S)-5,6,15-Trihydroxy-17-Methoxy-11-Methyl-12-Oxabicyclo[12.4.0]Octadeca-1(14),2,8,15,17-Pentaene-7,13-Dione 2
NPC94428 K-252A 2
NPC196449 Calcimycin 2
NPC228343 Nordihydroguaiaretic Acid 2
NPC95162 Fraxetin 2
NPC307176 Progesterone 2
NPC250999 Zinc;1-Oxidopyridine-2-Thione 2
NPC274721 7,11B-Dihydro-6H-Indeno[2,1-C]Chromene-3,6A,9,10-Tetrol 2
NPC43945 Menadione 2
NPC294902 Caffeic Acid 2
NPC50898 Apigenin 2
NPC95412 Antimycin A 2
NPC179787 Harman 2
NPC471785 Sid11111800 2
NPC310259 Pentamethylquercetin 2
NPC113006 5-Hydroxy-2-(4-Hydroxyphenyl)Chromen-4-One 2
NPC115418 Dinoprostone 2
NPC257236 Rottlerin 2
NPC281398 Tanshinone Iia 2
NPC84478 Harmaline 1
NPC156461 Adenosine 1
NPC299990 n.a. 1
NPC9743 (+)-Epitaxifolin 1
NPC186098 Paeonol 1
NPC315216 7,12-Dimethylbenzo[A]Anthracene 1
NPC116961 Loratadine 1
NPC21638 n.a. 1
NPC262359 (E)-1-(2,4-Dihydroxyphenyl)-3-(4-Methoxyphenyl)Prop-2-En-1-One 1
NPC329003 Oleoylethanolamide 1
NPC133700 (5S)-5-Azaniumylcyclohexa-1,3-Diene-1-Carboxylate 1
NPC233380 Aldisin 1
NPC469976 4-(2-Amino-1H-Imidazol-5-Yl)-2,3-Dibromo-4,5,6,7-Tetrahydro-1H-Pyrrolo[2,3-C]Azepin-8-One 1
NPC18335 Adenine 1
NPC300596 Indirubin 1
NPC85707 Sl-0101 1
NPC188104 n.a. 1
NPC118522 L-Norepinephrine 1
NPC262635 Trioxsalen 1
NPC329416 Isotretinoin 1
NPC2414 2-Bromoaldisin 1
NPC235059 Cinnamaldehyde 1
NPC282923 Chrysophanol 1
NPC85276 Deoxiepinephrine 1
NPC300798 Pterocarpin 1
NPC473206 Diphenyleneiodonium 1
NPC102810 Tetrahydrogambogic Acid 1
NPC190461 n.a. 1
NPC317177 Tretinoin 1
NPC119133 Theobromine 1
NPC212866 Enniatin B 1
NPC263386 Caffeic Acid Phenethyl Ester 1
NPC329556 Ketoprofen 1
NPC136330 Piperine 1
NPC284475 Menatetrenone 1
NPC80596 Meridianin E 1
NPC88803 [5,7-Dihydroxy-2-(3,4,5-Trihydroxyphenyl)-3,4-Dihydro-2H-Chromen-3-Yl] 3,4,5-Trihydroxybenzoate 1
NPC300984 Lobaric Acid 1
NPC10915 Albizziine 1
NPC190572 Visnagin 1
NPC119224 Garcinone E 1
NPC213216 5,7-Dihydroxy-2-(2-Hydroxyphenyl)Chromen-4-One 1
NPC264293 Khellin 1
NPC138978 Altenusin 1
NPC476440 Tpck 1
NPC88923 Reserpine 1
NPC168027 Corticosterone 1
NPC302950 Hesperetin 1
NPC236347 Epinephrine 1
NPC13067 Prenyletin 1
NPC214036 Piplartine 1
NPC139397 Androstenedione 1
NPC287331 Eucalyptol 1
NPC8466 Crotonaldehyde 1
NPC172046 3-Hydroxybenzylhydrazine Dihydrochloride 1
NPC303422 Piceid 1
NPC105488 Cycloserine 1
NPC237712 Desoxycorticosterone 1
NPC319628 1,4-Bis[[(E)-3-(3,4-Dihydroxyphenyl)Prop-2-Enoyl]Oxy]-3,5-Dihydroxycyclohexane-1-Carboxylic Acid 1
NPC215584 Elliptecine 1
NPC31171 Cytochalasin B 1
NPC139813 (E)-1-(2-Hydroxy-4-Methoxyphenyl)-3-(4-Methoxyphenyl)Prop-2-En-1-One 1
NPC150978 Angustibalin 1
NPC1502 Propionaldehyde 1
NPC172262 7-Hydroxy-2-(4-Hydroxyphenyl)Chromen-4-One 1
NPC304788 Benzoquinone 1
NPC55068 Sphingosine 1
NPC105648 Lecanoric Acid 1
NPC192533 2-Anilinonaphthalene-1,4-Dione 1
NPC319933 2,4-Dibromo-1-(2,4-Dibromophenoxy)Benzene 1
NPC13470 Cephalexin 1
NPC225539 Furan 1
NPC265782 E-Guggulsterone 1
NPC215837 Streptonigrin 1
NPC2476 5-Demethylnobiletin 1
NPC289979 Avocadyne Acetate 1
NPC90875 Oxopurpureine 1
NPC176740 Rutin 1
NPC305518 Xanthoxylin 1
NPC55412 Retinol 1
NPC107009 Carmine 1
NPC194562 Transtorine 1
NPC320891 2,2-Dihydroxyindene-1,3-Dione 1
NPC125416 Chlorhexidine 1
NPC140359 4-(2-Aminoethyl)-2-Methoxyphenol 1
NPC291548 n.a. 1
NPC93730 Flavonol 1
NPC176775 Gardenin B 1
NPC36229 Palmatine Chloride 1
NPC108288 Juglone 1
NPC321011 2-(3,4-Dihydroxyphenyl)-5,7-Dihydroxy-2,3-Dihydrochromen-4-One 1
NPC125549 1-Chloro-4-(4-Chlorophenyl)Sulfonylbenzene 1
NPC23155 1,3-Dihydroxypropan-2-Yl Hexadecanoate 1
NPC272426 Sodium Lauryl Sulfate 1
NPC74357 Caulibugulone B 1
NPC72980 Harmalol 1
NPC141791 2-Phenylethyl (Z)-3-(3,4-Dihydroxyphenyl)Prop-2-Enoate 1
NPC33320 Methoxsalen 1
NPC168803 7,8-Dihydroxyflavone 1
NPC94167 Riboflavin 1
NPC176814 Arctigenin 1
NPC306195 Bisabolol 1
NPC109083 Curcumin 1
NPC195314 Staurosporinone 1
NPC248956 (1S,5R)-9-Methyl-9-Azabicyclo[3.3.1]Nonan-3-One 1
NPC321402 (8R,9S,13S,14S,17S)-13-Methyl-6,7,8,9,11,12,14,15,16,17-Decahydrocyclopenta[A]Phenanthrene-2,3,17-Triol 1
NPC128216 3,5-Dihydroxy-2-Phenylchromen-4-One 1
NPC24019 Oxoglaucine 1
NPC273037 Quisqualate 1
NPC473417 Trifluoperazine 1
NPC143168 Embelin 1
NPC177281 (10-Acetyloxy-8,8-Dimethyl-2-Oxo-9,10-Dihydropyrano[2,3-F]Chromen-9-Yl) 3-Methylbutanoate 1
NPC306238 (2S)-2-Acetamido-3-Sulfanylpropanoic Acid 1
NPC57565 Dalfampridine 1
NPC109403 Daunorubicin 1
NPC250834 Methyl Carbamimidothioate 1
NPC321869 2,4-Dinitrophenol 1
NPC128713 Alpha-Ketoglutaric Acid 1
NPC273758 Dibenzoylmethane 1
NPC73978 Phenylglyoxal 1
NPC16031 Dopa 1
NPC294409 Biochanin 1
NPC475112 Sid506289 1
NPC178134 Ellagic Acid 1
NPC61477 Catechin 1
NPC110396 2,6-Dimethoxyquinone 1
NPC322735 Parathion 1
NPC129533 n.a. 1
NPC228785 Mangostin 1
NPC77955 3',4'-Dimethoxyflavone 1
NPC146422 Dopamine 1
NPC309367 Thiram 1
NPC62735 Rataniaphenol Ii 1
NPC12377 Cladrin 1
NPC202146 n.a. 1
NPC324772 Calcitriol 1
NPC129578 Rohitukine 1
NPC229113 Dicumarol 1
NPC275960 Helenalin 1
NPC44530 Hematoxylin 1
NPC78222 (6As)-2,9,10-Trimethoxy-6-Methyl-5,6,6A,7-Tetrahydro-4H-Dibenzo[De,G]Quinoline-1-Ol 1
NPC294941 O,O'-Dimethylcaffeic Acid 1
NPC95429 2-(2-Phenylpropan-2-Ylperoxy)Propan-2-Ylbenzene 1
NPC180006 Auraptene 1
NPC202771 Noscapine 1
NPC255345 Fluoranthene 1
NPC325452 2-Ethylhexanoic Acid 1
NPC13991 Alpha-Pinene 1
NPC231772 Acacetin 1
NPC280026 Lithocholic Acid 1
NPC78540 Chrysin 1
NPC149300 Tannic Acid 1
NPC150592 4,5-Dibromopyrrole-2-Carbamide 1
NPC297186 2',4'-Dihydroxychalcone 1
NPC469897 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine 1
NPC95977 Pramoxine 1
NPC313618 Oxybenzone 1
NPC115159 (Z)-1-(2,4-Dihydroxyphenyl)-3-(4-Hydroxyphenyl)Prop-2-En-1-One 1
NPC204985 5,7-Dihydroxy-3-(4-Hydroxyphenyl)-6,8-Bis(3-Methylbut-2-Enyl)Chromen-4-One 1
NPC255550 Capsaicin 1
NPC328750 Laudanosine 1
NPC231884 (S)-Verapamil 1
NPC281131 Hyperoside 1
NPC45404 Piperonylic Acid 1
NPC80129 (2S,3S,11Bs)-2-[[(1R)-6,7-Dimethoxy-1,2,3,4-Tetrahydroisoquinolin-1-Yl]Methyl]-3-Ethyl-9,10-Dimethoxy-2,3,4,6,7,11B-Hexahydro-1H-Benzo[A]Quinolizine 1
NPC7839 n.a. 1
NPC156021 Lawsone 1
NPC298257 [(2R,3R,4R,5R,6R)-6-[2-(3,4-Dihydroxyphenyl)Ethoxy]-5-Hydroxy-2-[[(2R,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Oxan-2-Yl]Oxymethyl]-4-[(2S,3R,4R,5R,6S)-3,4,5-Trihydroxy-6-Methyloxan-2-Yl]Oxyoxan-3-Yl] (E)-3-(3,4-Dihydroxyphenyl)Prop-2-Enoate 1
NPC472861 (4E)-4-(2-Amino-4-Oxo-1H-Imidazol-5-Ylidene)-2-Bromo-1,5,6,7-Tetrahydropyrrolo[2,3-C]Azepin-8-One 1
NPC180508 Pterostilbene 1
NPC313884 n.a. 1
NPC206148 Oroidin 1
NPC41719 Karanjin 1
NPC232727 Harmine 1
NPC469949 Clofazimine 1

  Download Data Related to This Target

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2. Biological Activity: activity records of all natural products that have available activity against this target;
3. Compound Information: compound related data of all natural products that have available activity against this target;
4. Species Source: species sources that all natural products that have available activity against this target derived from.

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