Natural Product Target: Cyclooxygenase-2

Target ID:   NPT31
Target Name:   Cyclooxygenase-2
Target Type:   Individual Protein
Organism of Target:   Homo sapiens
Target External ID:   Uniprot_ID:[ P35354]

  Biological Activities of Natural Products against the Target

Natural Product ID Natural Product Name # Activity Records
NPC316910 Celecoxib 185
NPC274455 Ibuprofen 29
NPC311219 Aspirin 23
NPC111088 Naproxen 13
NPC161571 Resveratrol 9
NPC329556 Ketoprofen 8
NPC91105 2,4,6-Trihydroxy-3-Geranylacetophenone 5
NPC279121 Luteolin 5
NPC471593 Sc-560 4
NPC109083 Curcumin 4
NPC257124 Eugenol 4
NPC106601 Cassiatannin A 3
NPC207554 Tryptanthrin 3
NPC131624 Wogonin 3
NPC110701 n.a. 3
NPC35185 Loganin 3
NPC136699 Aucubin 3
NPC161293 Gardoside 3
NPC220167 Bartioside 3
NPC206815 6-O-Veratroylcatalpol 3
NPC241911 Geniposidic Acid 3
NPC304163 Plantarenaloside 3
NPC4809 Cinnamtannin B1 3
NPC287539 Loganic Acid 3
NPC63897 Boschnaloside 3
NPC166287 Lipoic Acid 3
NPC473149 n.a. 3
NPC46274 Cyanidin 3
NPC142415 Oleanolic_Acid 3
NPC37240 Mussaenoside 3
NPC147743 Cinnamtannin D1 3
NPC258501 Catalpol 3
NPC473150 n.a. 3
NPC151474 n.a. 3
NPC77922 Agnuside 3
NPC177013 8-Epiloganin 3
NPC78540 Chrysin 2
NPC280254 Pyrogallol 2
NPC235059 Cinnamaldehyde 2
NPC51700 Ursolic Acid 2
NPC471898 4,(23)-Dihydro-11-Keto-Roburic Acid 2
NPC107039 Roburic Acid 2
NPC21429 Rutaecarpine 2
NPC159046 3-Beta-Hydroxy-8,24-Diene-Tirucallic Acid 2
NPC142361 3-Alpha-Hydroxy-7,24-Diene-Tirucallic Acid 2
NPC38350 Beta-Elemonic Acid 2
NPC219876 Cianidanol 2
NPC20791 Quercetin 2
NPC50898 Apigenin 2
NPC148414 3-Alpha-Acetoxy-8,24-Diene-Tirucallic Acid 2
NPC471902 3-O-Acetyl-28-Hydroxy-Lupeolic Acid 2
NPC61871 5,6-Dihydroxy-7-Methoxy-2-Methylchromen-4-One 2
NPC228343 Nordihydroguaiaretic Acid 2
NPC62840 Morusin 2
NPC294902 Caffeic Acid 2
NPC76327 Acetaminophen 2
NPC31872 Eugenin 2
NPC176309 Levomenthol 2
NPC76336 Scopoletin 2
NPC30647 Stellatin 2
NPC154256 (2S)-2-(Hydroxymethyl)-2-Methylchromen-6-Ol 1
NPC471897 4,(23)-Dihydro-Roburic Acid 1
NPC262328 Engeletin 1
NPC209058 Artanomalide D 1
NPC178383 Betulin 1
NPC471126 n.a. 1
NPC300326 Sinapinate 1
NPC47398 Ouratea-Catechin 1
NPC100925 Clematernoside D 1
NPC155144 Moracin M 1
NPC471899 4,(23)-Dihydro-Nyctanthic Acid 1
NPC263386 Caffeic Acid Phenethyl Ester 1
NPC78803 Cudraflavone B 1
NPC280827 Pulveraven B 1
NPC179169 R-Bisabolol 1
NPC300894 Forsythoside B 1
NPC469461 Alstoyunine E 1
NPC131874 Tremulacin 1
NPC93619 2'-Benzolypoliothyrsoside 1
NPC236588 13,14,15,16-Tetranorlabdane-8Alpha,12,14-Triol 1
NPC135334 Clematernoside E 1
NPC159630 Trigonelline Hydrochloride 1
NPC473451 (+)-3,3'-Bisdemethyltanegool 1
NPC61 Rosmarinic Acid 1
NPC281521 Bauhinoxepin F 1
NPC179950 Isoquercetin 1
NPC301702 Aminosalicylic Acid 1
NPC211561 Ourateaproanthocyanidin A 1
NPC161277 2,6-Dihydroxy-1,7-Dimethoxyxanthone 1
NPC131981 Camphor 1
NPC31081 3'-Benzoylsalicin 1
NPC236638 Huzhangoside B 1
NPC77777 Alstoyunine G 1
NPC237946 Podofilox 1
NPC469773 Clematochinenoside C 1
NPC476111 n.a. 1
NPC160900 (1E,6E)-1,7-Bis(4-Hydroxy-3-Methoxyphenyl)Hepta-1,6-Diene-3,5-Dione 1
NPC173352 Radicicol 1
NPC298034 3-O-Beta-D-Glucopyranosyl-(1-4)-Beta-D-Glucopyranosyl-(1?-)-Beta-D-Ribopyranosyl-(1-3)-Alpha-L-Rhamnopyranosyl-(1-2)-Alpha-L-Arabinopyranosylhederagenin 28-O-Alpha-L-Rhamnopyranosyl-(1-4)-Beta-D-Glucopyranosyl-(1-6)-Beta-Dglucopyranoside 1
NPC81010 Coumaric Acid 1
NPC32441 Naringenin 1
NPC20287 Gingerol 1
NPC22098 Citronellal 1
NPC145182 n.a. 1
NPC228907 Pyrocatechol-O-Beta-D-Diglucopyranoside 1
NPC138927 Myricetin-3-O-Beta-D-Glucuronide 1
NPC9248 Pyrocatechol-O-Beta-D-Glucopyranoside 1
NPC238593 Ergolide 1
NPC474401 4-Hydroxytremulacin 1
NPC243902 n.a. 1
NPC472398 n.a. 1
NPC472209 n.a. 1
NPC82016 Trismethoxyresveratrol 1
NPC283823 Isovanillic Acid 1
NPC180508 Pterostilbene 1
NPC35344 Methylhonokiol 1
NPC47844 Shikimic Acid 1
NPC139548 Isoscopoletin 1
NPC128496 n.a. 1
NPC241909 Cauloside D 1
NPC476026 Itoside C 1
NPC474565 Rhapontigenin 1
NPC264477 Enhydrin 1
NPC67608 Artanomalic Acid 1
NPC476927 (E)-5-[(1R,2R,4aR,5R,8aS)-5-(acetyloxymethyl)-2-hydroxy-2,5,8a-trimethyl-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl]-3-methylpent-2-enoic acid 1
NPC83287 Ouabain 1
NPC285923 Nalidixic Acid 1
NPC261506 Clematichinenoside C 1
NPC112789 Gemichalcone B 1
NPC302857 Chlorogenic Acid 1
NPC472401 n.a. 1
NPC139891 Coumarin 1
NPC474398 Itoside D 1
NPC266931 N-Feruloyl Serotonin 1
NPC165770 3-(Gamma,Gamma-Dimethylallyl)Resveratrol 1
NPC43525 5-(Gamma,Gamma-Dimethylallyl)-Oxyresveratrol 1
NPC476928 2-[(1R,2R,4aR,5R,8aS)-2-hydroxy-5-(hydroxymethyl)-2,5,8a-trimethyl-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl]ethyl acetate 1
NPC86372 Boswellic Acid 1
NPC287331 Eucalyptol 1
NPC189844 Demethoxycurcumin 1
NPC71065 Clematichinenoside B 1
NPC115144 Trans-2-(3',4'-Dihydroxy-Phenyl)-3-Acetylamino-7-(N-Acetyl-2''-Aminoethyl)-1,4-Benzodioxane 1
NPC220765 Serotonin 1
NPC40377 Salirepin 1
NPC142319 Arbutin 1
NPC247553 Umbelliferone 1
NPC49130 Dihydromorin 1
NPC469470 Alstoyunine A 1
NPC268342 Gallocatechin 1
NPC166040 Vanilloloside 1
NPC475174 Itoside J 1
NPC53463 Glyceryl Monostearate 1
NPC87777 Afzelechin-3-O-Alpha-Lrhamnopyranoside 1
NPC190753 Psilostachyin A 1
NPC471896 3-Alpha-Acetoxy-7,24-Diene-Tirucallic Acid 1
NPC115207 (-)-Pinoresinol 1
NPC35856 Anacardic Acid 1
NPC223451 3-(2,3-Dihydroxy-3-Methylbutyl)Resveratrol 1
NPC475250 Dadahol A 1
NPC142339 Gama-Mangostin 1
NPC469462 Alstoyunine F 1
NPC250436 Epigalocatechin Gallate 1
NPC471901 3-O-Acetyl-Lupeolic Acid 1
NPC68269 Bisdemethoxycurcumin 1
NPC269206 Costunolide 1
NPC53879 n.a. 1
NPC92403 Sennoside B 1
NPC292233 Sanggenon B 1
NPC20830 Cirsilineol 1
NPC115418 Dinoprostone 1
NPC309399 Abietic Acid 1
NPC225710 Gallic Acid 1
NPC473909 Dadahol B 1
NPC230439 Itoside G 1
NPC252603 Theophylline 1
NPC469501 Alstoyunine B 1
NPC471900 Lupeolic Acid 1
NPC70940 Dexibuprofen 1
NPC271921 2,3-Dihydroxypropyl (9Z,12Z,15Z)-Octadeca-9,12,15-Trienoate 1
NPC167400 Niacin 1
NPC469460 Alstoyunine D 1
NPC59692 Resveratrol (E)-Dehydrodimer 11-O-Beta-D-Glucopyranoside 1
NPC96565 Kuwanon C 1
NPC292452 Oxyresveratrol 1
NPC200237 Burrodin 1
NPC332382 Metronidazole 1
NPC116775 Kaempferol 1
NPC226712 Salicin 1
NPC146615 Bauhinoxepin H 1
NPC279281 Itoside H 1
NPC256849 Caffeine 1
NPC146355 (-)-3,3'-Bisdemethylpinoresinol 1
NPC71686 n.a. 1
NPC274121 Norartocarpetin 1
NPC169749 Myricetin 1
NPC475183 Itoside B 1
NPC97578 Pallidol 1
NPC294548 Linolenic Acid 1
NPC200752 3 Beta-O-Acetyloleanolic Acid 1
NPC115352 Artanomalide B 1
NPC118343 Benzyl Benzoate 1
NPC469772 Clematochinenoside A 1
NPC2524 8Alpha,19-Dihydroxylabd-13 E-En-15-Oic Acid 1
NPC92153 Itoside E 1
NPC50362 Parthenolide 1
NPC469776 Clematochinenoside F 1
NPC73995 Encelin 1
NPC174720 Ciwujianoside C3 1
NPC140722 Itoside A 1
NPC99666 N-P-Coumaroyl Serotonin 1
NPC201357 Bauhinoxepin E 1
NPC266937 Avarol 1
NPC119036 Bruguierin A 1
NPC24824 Citronellol 1
NPC250312 Ashwagandhanolide 1
NPC299761 Itoside F 1
NPC179862 Itoside N 1
NPC469782 Kizuta Saponin K12 1
NPC76145 Limonene 1
NPC277857 Trans-2-(3',4'-Dihydroxy-Phenyl)-3-Acetylamino-6-(N-Acetyl-2''-Aminoethyl)-1,4-Benzodioxane 1
NPC19622 Isogemichalcone B 1
NPC132938 Itoside L 1
NPC64250 Pipecolic Acid 1
NPC100340 Dihydropinosylvin 1
NPC294941 O,O'-Dimethylcaffeic Acid 1
NPC201419 Bauhinoxepin I 1
NPC472399 n.a. 1
NPC119592 Huzhangoside D 1
NPC317474 Atropine 1
NPC230713 3-(Gamma,Gamma-Dimethylpropenyl)Moracinm 1
NPC469774 Clematochinenoside D 1
NPC148523 11-Keto Boswellic Acid 1
NPC474422 Poliothyrsin 1
NPC259512 Thymol 1
NPC189661 Alstoyunine H 1
NPC472400 n.a. 1
NPC472397 n.a. 1
NPC65003 Rhoifolin 1
NPC102439 Kizuta Cirensenoside O Saponin K3 1
NPC295261 Steppogenin 1
NPC204251 Ajoene 1
NPC308976 (+)-3,4,3',4'-Tetrahydroxy-9,7'alpha-Epoxylignano-7 Alpha,9'-Lactone 1
NPC13385 2-Ethoxycarbonyl-2Beta-Hydroxy-A-Nor-Ergosta-5,24(28)-Dien-4-One 1
NPC318325 4-Octylphenol 1
NPC233836 3-Alpha-Hydroxy-8,24-Diene-Tirucallic Acid 1
NPC469775 Clematochinenoside E 1
NPC150624 Batatasin Iv 1
NPC474441 Homaloside D 1
NPC30563 Hydrangeifolin I 1
NPC21378 Arzanol 1
NPC278552 Epiafzelechin (2R,3R)(-) 1
NPC176740 Rutin 1
NPC4328 Clematomandshurica Saponin C 1
NPC65517 Hydroquinone 1
NPC104071 Cirensenoside O 1
NPC296920 Resveratrol 4'-Methyl Ether 1
NPC205864 Arenarioside 1
NPC32723 Clematernoside B 1
NPC120163 Cirsimaritin 1
NPC318965 Norbelladine 1
NPC233980 Kazinol B 1
NPC469777 Clematochinenoside G 1
NPC4958 Poliothyrsoside 1
NPC189393 n.a. 1
NPC295941 Clematernoside K 1
NPC90814 n.a. 1
NPC67857 Hederasaponin B 1
NPC104537 Glyceryl Monooleate 1
NPC299590 Triptolide 1
NPC206264 Esculin 1
NPC474276 Sanggenon D 1
NPC125579 Resveratrol (E)-Dehydrodimer 1
NPC328877 Phenothiazine 1
NPC234333 4'-O-Me-Ent-Gallocatechin 1
NPC469778 Clematernoside C 1

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3. Compound Information: compound related data of all natural products that have available activity against this target;
4. Species Source: species sources that all natural products that have available activity against this target derived from.

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