Component: Evodia rutaecarpa 吴茱萸


Description of the Component

Component ID
TCMH2216
Latin Name
Evodia rutaecarpa
English Name
Medicinal evodia
Chinese Pinyin Name
Wu Zhu Yu
中文名
吴茱萸
TCM Properties
Pungent, bitter, hot
TCM Meridians
Liver, spleen,stomach
Therapeutic Class English
For warming interior
Therapeutic Class Chinese
温里
Functions
dispel cold and stop pain, pacify the liver and direct rebellious qi downward, stop vomiting
Toxicity
slightly toxic
Geo-authentic habitats (道地产区)
Hunan Province
Reference
Chinese Pharmacopoeia (2015)
Barcode ID
Barcode Source

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name
TCMF1333 Aifu Nuangong Pills 艾附暖宫丸
TCMF2100 Aifu Nuangong Pills 艾附暖宫丸
TCMF734 Bi Ling Wei Tong Granules 荜铃胃痛颗粒
TCMFx564 Chang Kang Tablet 肠康片
TCMFx3067 Chang Kang Tablets 肠康片
TCMF1892 Cock-Crowing Powder 鸡鸣散
TCMF353 Dan Gui Xiang Granules 丹桂香颗粒
TCMF2205 Decoction of Excrementum Bombycis, Bombyx Droppings Decoction 蚕矢汤
TCMF147 Diao Jing Huo Xue Capsule 调经活血胶囊
TCMFx172 E Zhang Feng Yao Shui 鹅掌风药水
TCMFx6908 Er Xie Kang Tie Mo 儿泻康贴膜
TCMF3087 Er Yi Pills 二益丸
TCMF2651 Evodia Decoction 吴茱萸汤
TCMF1678 Evodia Decoction 吴茱萸汤
TCMFx3308 Feng Qie Ping Chuan Ointment 风茄平喘膏
TCMF1816 Four Deity Pills 四神丸
TCMF3756 Fu Bao Jin Pills 妇宝金丸
TCMFx3585 Fu Fang Huang Lian Su Tablets 复方黄连素片
TCMFx3048 Fu Fang Tian Qi Wei Tong Capsules 复方田七胃痛胶囊
TCMFx3056 Fu Fang Tian Qi Wei Tong Tablets 复方田七胃痛片
TCMF3371 Fu Fang Zhi Jin Gan Infusion 复方制金柑冲剂
TCMF3117 Fu Gui Feng Shi Ointment 附桂风湿膏
TCMF3502 Gan Lu Ointment 甘露膏
TCMFx4786 Hu Xin Capsules 护心胶囊
TCMFx365 Hua Zheng Hui Sheng Tablet 化症回生片
TCMFx1703 Huatuo Zaizao Pills 华佗再造丸
TCMFx1251 Huatuo Zaizao Pills 华佗再造丸
TCMF2365 Interior Benefiting Stamoch Decoction 益中活血汤
TCMF7315 Ji Ming Powder 鸡鸣散
TCMFx4761 Jia Wei Lan Ji Pills 加味烂积丸
TCMF518 Jia Wei Xiang Lian Pills 加味香连丸
TCMF4834 Jia Wei Xiang Lian Pills 加味香连丸
TCMF4866 Jia Wei Zuo Jin Pills 加味左金丸
TCMF516 Jia Wei Zuo Jin Pills 加味左金丸
TCMFx4716 Ju He Shan Qi Pills 橘核疝气丸
TCMFx4796 Jun Li Ping Tablets 菌痢平片
TCMF2423 Meridian Warming Decoction 温经汤
TCMF4472 Min Dong Jian Qu 闽东建曲
TCMF4620 Mu Xiang Li Qi Tablets 木香理气片
TCMFx4794 Nao Sai Tong Pills 脑塞通丸
TCMFx4378 Nv Bao Capsules 女宝胶囊
TCMF1272 Pill of Four Miraculous Drugs; Four Deity Pill 四神丸
TCMF5608 Rou Kou Si Shen Pills 肉蔻四神丸
TCMF5193 San Yu Shen Qu 三余神曲
TCMFx5604 Shan Qi Pills 疝气丸
TCMFx5753 Shang Shi Zhen Tong Ointment 伤湿镇痛膏
TCMFx5047 She Yao Pills 蛇咬丸
TCMF3212 Shen Gui Tiao Jing Pills 参桂调经丸
TCMFx3597 Shen Rong Lu Tai Ointment 参茸鹿胎膏
TCMF5909 Shi Er Wen Jing Pills 十二温经丸
TCMFx5797 Si Fang Wei Capsules 四方胃胶囊
TCMFx449 Si Fang Wei Tablet 四方胃片
TCMFx5804 Si Fang Wei Tablets 四方胃片
TCMF447 Si Shen Tablet 四神片
TCMF5931 Si Shen Tablets 四神片
TCMF2407 Stomach Pain Recipe 胃脘痛方
TCMFx2200 Stomach Pain Tested Recipe 胃炎验方
TCMF5628 Tiao Jing Huo Xue Tablets 调经活血片
TCMF967 Tiao Jing Huo Xue Tablet 调经活血片
TCMFx963 Tiao Jing Pills 调经丸
TCMFx5163 Tou Gu Zhen Feng Pills 透骨镇风丸
TCMF2652 Warm the Menses Decoction 温经汤
TCMFx5572 Wei Bing Pills 胃病丸
TCMF7062 Wei Li Kang Granules 胃力康颗粒
TCMFx801 Wei Li Kang Tablet 胃立康片
TCMFx5720 Wei Li Kang Tablets 胃立康片
TCMF7402 Wen Jing Decoction 温经汤
TCMF5924 Wen Jing Pills 温经丸
TCMF5932 Wen Jing Yang Xue Recipe 温经养血合剂
TCMFx430 Wu Ji Pills 戊己丸
TCMFx5477 Wu Jia Pills 五瘕丸
TCMFx5246 Wu Jin Pills 乌金丸
TCMFx5239 Wu Jin Tablets 乌金片
TCMFx5561 Wu Wei Xiang Lian Pills 五味香连丸
TCMF7303 Wu Zhu Yu Decoction 吴茱萸汤
TCMF2794 Wu Zhu Yu Decoction 吴茱萸汤
TCMFx6776 Xiao Er Jian Pi Tie Ointment 小儿健脾贴膏
TCMF6172 Xiao Er Nuan Qi Ointment 小儿暖脐膏
TCMF6688 Xie Li Bao Tong Pills 泻痢保童丸
TCMF681 Xie Li Xiao Capsule 泻痢消胶囊
TCMF6718 Xie Li Xiao Capsules 泻痢消胶囊
TCMFx1189 Xuan Shi Solution 癣湿药水
TCMFx6077 Yang Yin Jiang Ye Capsules 养阴降压胶囊
TCMFx6333 Yu Lian Tablets 萸连片
TCMFx6057 Zhi Li Tablets 治痢片
TCMF6662 Zhi Xie Bao Tong Infusion 止泻保童冲剂
TCMFx405 Zuo Jin Capsule 左金胶囊
TCMFx1211 Zuojin Bolus; Left Gold Pill; Liver-fire-Purging and Stomach-Regulating Pill 左金丸
TCMFx1505 Zuojin Bolus; Left Gold Pills 左金丸

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT1 EHMT2 Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 Transferase Q96KQ7
TCMT11 HIF1A Hypoxia-inducible factor 1 alpha Transcription factor Q16665
TCMT13 APEX1 DNA-(apurinic or apyrimidinic site) lyase Lyase P27695
TCMT150 RORC Nuclear receptor ROR-gamma Nuclear receptor P51449
TCMT156 CYP19A1 Cytochrome P450 19A1 Oxidoreductase P11511
TCMT17 POLB DNA polymerase beta Transferase P06746
TCMT2 MAPT Microtubule-associated protein tau Unclassified P10636
TCMT248 CXCL8 Interleukin-8 Unclassified P10145
TCMT261 DAPK1 Death-associated protein kinase 1 Kinase P53355
TCMT3 ALOX15 Arachidonate 15-lipoxygenase Oxidoreductase P16050
TCMT313 HTR2B Serotonin 2b (5-HT2b) receptor GPCR P41595
TCMT314 HTR2C Serotonin 2c (5-HT2c) receptor GPCR P28335
TCMT315 HTR6 Serotonin 6 (5-HT6) receptor GPCR P50406
TCMT316 MTNR1A Melatonin receptor 1A GPCR P48039
TCMT317 MTNR1B Melatonin receptor 1B GPCR P49286
TCMT321 MMP9 Matrix metalloproteinase 9 Hydrolase P14780
TCMT33 CYP3A4 Cytochrome P450 3A4 Oxidoreductase P08684
TCMT34 CYP2D6 Cytochrome P450 2D6 Oxidoreductase P10635
TCMT36 HTR1A Serotonin 1a (5-HT1a) receptor GPCR P08908
TCMT37 HTR2A Serotonin 2a (5-HT2a) receptor GPCR P28223
TCMT45 APP Beta amyloid A4 protein Unclassified P05067
TCMT609 CTSL Cathepsin L Unclassified P07711
TCMT637 SIRT3 NAD-dependent deacetylase sirtuin 3 Hydrolase Q9NTG7
TCMT638 SIRT2 NAD-dependent deacetylase sirtuin 2 Hydrolase Q8IXJ6
TCMT8 KDM4E Lysine-specific demethylase 4D-like Oxidoreductase B2RXH2
TCMT87 CYP2C9 Cytochrome P450 2C9 Oxidoreductase P11712


Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1109 Reverse transcriptase
TCMT1121 Sialidase
TCMT1136 Neuraminidase
TCMT1255 Human immunodeficiency virus 1
TCMT1318 Human T-lymphotropic virus 1
TCMT1454 Bacillus subtilis
TCMT1462 Streptococcus mutans

Ingredient Structrues

Ingredient ID: TCMC7366
Formula: C28H32O10

Ingredient ID: TCMC7252
Formula: C25H37NO

Ingredient ID: TCMC6984
Formula: C26H28O8

Ingredient ID: TCMC6123
Formula: C26H28O10

Ingredient ID: TCMC6061
Formula: C19H27NO

Ingredient ID: TCMC5692
Formula: C16H16O6

Ingredient ID: TCMC555
Formula: C13H18N2O

Ingredient ID: TCMC5246
Formula: C26H30O9

Ingredient ID: TCMC5232
Formula: C19H15N3O

Ingredient ID: TCMC4987
Formula: C10H16

Ingredient ID: TCMC4897
Formula: C23H35NO

Ingredient ID: TCMC4776
Formula: C21H31NO

Ingredient ID: TCMC4775
Formula: C21H29NO

Ingredient ID: TCMC4774
Formula: C21H29NO

Ingredient ID: TCMC4769
Formula: C23H31NO

Ingredient ID: TCMC4768
Formula: C23H33NO

Ingredient ID: TCMC4766
Formula: C25H39NO

Ingredient ID: TCMC4765
Formula: C25H37NO

Ingredient ID: TCMC4764
Formula: C25H37NO

Ingredient ID: TCMC4763
Formula: C25H35NO

Ingredient ID: TCMC4752
Formula: C22H33NO

Ingredient ID: TCMC4744
Formula: C18H19N3O

Ingredient ID: TCMC4603
Formula: C19H17N3O2

Ingredient ID: TCMC4602
Formula: C19H19N3O

Ingredient ID: TCMC4561
Formula: C19H15N3O2

Ingredient ID: TCMC4555
Formula: C23H33NO

Ingredient ID: TCMC4422
Formula: C14H24O2

Ingredient ID: TCMC421
Formula: C9H10O3

Ingredient ID: TCMC4045
Formula: C22H33NO

Ingredient ID: TCMC403
Formula: C20H29NO

Ingredient ID: TCMC3708
Formula: C19H21N3O

Ingredient ID: TCMC3689
Formula: C26H28O9

Ingredient ID: TCMC3379
Formula: C8H10N2O

Ingredient ID: TCMC3369
Formula: C19H17N3O2

Ingredient ID: TCMC3300
Formula: C11H10N2O

Ingredient ID: TCMC2907
Formula: C10H9NO

Ingredient ID: TCMC284
Formula: C10H16

Ingredient ID: TCMC2324
Formula: C10H16

Ingredient ID: TCMC2030
Formula: C18H13N3O

Ingredient ID: TCMC1808
Formula: C9H13NO2

Ingredient ID: TCMC1622
Formula: C19H17N3O

Ingredient ID: TCMC1491
Formula: C26H30O8

Ingredient ID: TCMC1286
Formula: C15H10O8

Ingredient ID: TCMC1166
Formula: C19H17N3O

Properties

Ingredient ID Formulae Name MW AlogP MlogP XlogP # HBA # HBD PSA # Rotatable Bond # Ring # Heacy Atom Lipinski RO5 Violation
TCMC284 C10H16 1-Methyl-4-Prop-1-En-2-Ylcyclohexene 136.13 2.1424 2.56 3.729 0 0 0 3 1 10 0
TCMC403 C20H29NO 2-Undecyl-1H-Quinolin-4-One 299.22 -3.055 3.44 7.659 2 1 29.1 11 2 22 1
TCMC421 C9H10O3 3,4-Dimethoxybenzaldehyde 166.06 -0.296 2.12 1.559 1 0 35.53 5 1 12 0
TCMC555 C13H18N2O 5-Meo-Dmt 218.14 0.0128 2.56 1.695 2 1 28.26 7 2 16 0
TCMC1166 C19H17N3O Evodiamine 303.14 -0.5403 3.11 3.89 4 1 39.34 1 5 23 0
TCMC1286 C15H10O8 Gossypetin 318.04 -3.2615 2.23 0.847 2 6 147.68 7 3 23 1
TCMC1491 C26H30O8 Limonin 470.19 -0.4484 3.44 1.644 7 0 104.57 5 7 34 0
TCMC1622 C19H17N3O 303.14 -0.5403 3.11 3.89 4 1 39.34 1 5 23 0
TCMC1808 C9H13NO2 Oxedrine 167.09 -1.2775 2.12 0.464 2 3 52.49 6 1 12 0
TCMC2030 C18H13N3O Rutaecarpine 287.11 -0.7533 3 3.951 4 1 48.46 0 5 22 0
TCMC2324 C10H16 Limonene 136.13 2.1424 2.56 3.729 0 0 0 3 1 10 0
TCMC2907 C10H9NO Echinopsine 159.0684139 -1.1745 2.34 1.668 2 0 17.07 0 2 12 0
TCMC3300 C11H10N2O 1,2,3,4-Tetrahydro-1-Oxo-Β-Carboline 186.0793129 -0.788 2.34 2.131 3 2 44.89 0 3 14 0
TCMC3369 C19H17N3O2 Hydroxyevodiamine 319.1320768 -1.2296 3 4.256 5 2 65.2 3 4 24 0
TCMC3379 C8H10N2O N-Methylanthranylamide 150.0793129 -0.9529 2.01 1.305 3 2 55.12 2 1 11 0
TCMC3689 C26H28O9 Evodol 484.1733325 -0.7398 3.33 1.088 8 1 124.8 1 7 35 0
TCMC3708 C19H21N3O Evodiamide 307.1684623 -1.0038 3.11 4.252 4 2 48.13 6 3 23 0
TCMC4045 C22H33NO 2-Tridecyl-4(1H)-Quinolone 326.2483896 -3.0836 3.66 8.548 2 0 29.43 12 2 24 2
TCMC4422 C14H24O2 Goshuyic Acid 223.169805 -0.4743 2.78 5.108 2 0 40.13 10 0 16 1
TCMC4555 C23H33NO Evocarpine 339.2562147 -1.3215 3.77 8.152 2 0 17.07 11 2 25 2
TCMC4561 C19H15N3O2 14-Formyldihydrorutaecarpine 317.1164267 -1.3595 3 3.443 5 1 56.41 1 5 24 0
TCMC4602 C19H19N3O Goshuyuamide I 305.1528122 -1.0945 3.11 4.116 4 2 48.13 3 4 23 0
TCMC4603 C19H17N3O2 Goshuyuamideii 319.1320768 -1.6806 3 3.499 5 1 49.93 3 4 24 0
TCMC4744 C18H19N3O N-(2-Methylaminobenzoyl)Tryptamine 293.1528122 -1.1061 3 4.11 4 3 56.92 6 3 22 0
TCMC4752 C22H33NO 1-Methyl-2-Dodecyl-4(1H)-Quinolone 327.2562147 -3.1645 3.66 8.099 2 0 17.07 11 2 24 2
TCMC4763 C25H35NO 1-Methyl-2-[(6Z,9Z)-6,9-Pentadecadienyl]-4(1H)-Quinolone 365.2718647 -0.5033 3.99 8.963 2 0 17.07 12 2 27 2
TCMC4764 C25H37NO 1-Methyl-2-[(Z)-6-Pentadecenyl]-4(1H)-Quinolone 367.2875148 -1.8975 3.99 9.29 2 0 17.07 13 2 27 2
TCMC4765 C25H37NO 1-Methyl-2-[(Z)-10-Pentadecenyl]-4(1H)-Quinolone 367.2875148 -1.8975 3.99 9.29 2 0 17.07 13 2 27 2
TCMC4766 C25H39NO 1-Methyl-2-Pentadecyl-4(1H)-Quinolone 369.3031649 -4.0285 3.99 9.806 2 0 17.07 14 2 27 2
TCMC4768 C23H33NO 1-Methyl-2-[(Z)-7-Tridecenyl]-4(1H)-Quinolone 339.2562147 -1.3215 3.77 8.152 2 0 17.07 11 2 25 2
TCMC4769 C23H31NO 1-Methyl-2-(4Z,7Z)-4,7-Tridecadienyl-4(1H)-Quinolinone 337.2405646 0.0727 3.77 7.825 2 0 17.07 10 2 25 1
TCMC4774 C21H29NO 1-Methyl-2-[(Z)-5-Undecenyl]-4(1H)-Quinolone 311.2249145 -0.7455 3.55 7.014 2 0 17.07 9 2 23 1
TCMC4775 C21H29NO 1-Methyl-2-[(Z)-6-Undecenyl]-4(1H)-Quinolone 311.2249145 -0.7455 3.55 7.014 2 0 17.07 9 2 23 1
TCMC4776 C21H31NO 1-Methyl-2-Undecyl-4(1H)-Quinolilone 313.2405646 -2.8765 3.55 7.53 2 0 17.07 10 2 23 1
TCMC4897 C23H35NO 2-Tridecyl-1-Methyl-4(1H)-Quinolone 341.2718647 -3.4525 3.77 8.668 2 0 17.07 12 2 25 2
TCMC4987 C10H16 Ocimene 136.1252005 3.0936 2.56 4.17 0 0 0 4 0 10 0
TCMC5232 C19H15N3O Dehydroevodiamine 301.1215121 -0.9675 3.11 3.564 4 0 29.43 0 5 23 0
TCMC5246 C26H30O9 Evodinone 486.1889827 -1.211 3.33 1.503 8 1 124.8 1 7 35 0
TCMC5692 C16H16O6 Arachidoside 304.0946882 -2.0855 2.56 0.496 1 4 99.38 2 3 22 0
TCMC6061 C19H27NO 1-Methyl-2-Nonyl-4(1H)-Quinolone 285.2092645 -2.3005 3.33 6.392 2 0 17.07 8 2 21 1
TCMC6123 C26H28O10 12Α-Hydroxyevodol 500.1682471 -1.3129 3.22 -0.153 9 2 145.03 1 7 36 0
TCMC6984 C26H28O8 Jangomolide 468.1784179 0.0489 3.44 1.83 7 0 104.57 1 7 34 0
TCMC7252 C25H37NO 1-Methyl-2-[(Z)-9-Pentadecenyl]-4(1H)-Quinolone 367.2875148 -1.8975 3.99 9.29 2 0 17.07 13 2 27 2
TCMC7366 C28H32O10 Rutaevin Acetate 528.1995474 -0.8319 3.44 1.814 9 0 130.87 3 7 38 0

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1. General Information of the Component  
2. TCM Prescriptions with the Component  
3. Putative Targets  
4. Activity & References for Filtering Putative Targets  
5. Ingredient Data & Chemical Structure Information (Properties, InChI, InChIkey, SMILES, etc.)