Component: Scutellaria baicalensis 黄芩浸膏


Description of the Component

Component ID
TCMH989
Latin Name
Scutellaria baicalensis
English Name
Extract of root of Baikal skullcaap
Chinese Pinyin Name
Huang Qin Jin Gao
中文名
黄芩浸膏
TCM Properties
TCM Meridians
Therapeutic Class English
Therapeutic Class Chinese
Functions
Toxicity
NA
Geo-authentic habitats (道地产区)
NA
Reference
Chinese Pharmacopoeia (2015)
Barcode ID
ITSAP4211-14
Barcode Source
BOLDSYSTEMS

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name
TCMF6984 Qin Huang Hou Zheng Capsules 芩黄喉症胶囊
TCMFx6870 San Huang Capsules 三黄胶囊
TCMFx220 San Huang Tablet 三黄片

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT1 EHMT2 Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 Transferase Q96KQ7
TCMT100 TTR Transthyretin Unclassified P02766
TCMT101 PTPN1 Protein-tyrosine phosphatase 1B Hydrolase P18031
TCMT11 HIF1A Hypoxia-inducible factor 1 alpha Transcription factor Q16665
TCMT125 GBA Beta-glucocerebrosidase Hydrolase P04062
TCMT126 TERT Telomerase reverse transcriptase Transferase O14746
TCMT127 PARP1 Poly [ADP-ribose] polymerase-1 Transferase P09874
TCMT128 TNKS2 Tankyrase-2 Transferase Q9H2K2
TCMT129 TNKS Tankyrase-1 Transferase O95271
TCMT13 APEX1 DNA-(apurinic or apyrimidinic site) lyase Lyase P27695
TCMT130 ALOX5 Arachidonate 5-lipoxygenase Oxidoreductase P09917
TCMT131 ACHE Acetylcholinesterase Hydrolase P22303
TCMT132 BCHE Butyrylcholinesterase Hydrolase P06276
TCMT133 CA1 Carbonic anhydrase I Lyase P00915
TCMT134 CA2 Carbonic anhydrase II Lyase P00918
TCMT135 CA14 Carbonic anhydrase XIV Lyase Q9ULX7
TCMT136 CA12 Carbonic anhydrase XII Lyase O43570
TCMT137 CA9 Carbonic anhydrase IX Lyase Q16790
TCMT138 CA7 Carbonic anhydrase VII Lyase P43166
TCMT139 CA6 Carbonic anhydrase VI Lyase P23280
TCMT140 CA5B Carbonic anhydrase VB Lyase Q9Y2D0
TCMT141 CA5A Carbonic anhydrase VA Lyase P35218
TCMT142 CA4 Carbonic anhydrase IV Lyase P22748
TCMT143 CA3 Carbonic anhydrase III Lyase P07451
TCMT150 RORC Nuclear receptor ROR-gamma Nuclear receptor P51449
TCMT151 PRKCA Protein kinase C alpha Kinase P17252
TCMT156 CYP19A1 Cytochrome P450 19A1 Oxidoreductase P11511
TCMT159 TYR Tyrosinase Oxidoreductase P14679
TCMT160 HTR7 Serotonin 7 (5-HT7) receptor GPCR P34969
TCMT161 HCAR2 Hydroxycarboxylic acid receptor 2 GPCR Q8TDS4
TCMT162 UGT1A1 UDP-glucuronosyltransferase 1-1 Transferase P22309
TCMT171 PTPN6 Protein-tyrosine phosphatase 1C Hydrolase P29350
TCMT176 SOAT1 Acyl coenzyme A:cholesterol acyltransferase 1 Transferase P35610
TCMT187 AR Androgen Receptor Nuclear receptor P10275
TCMT189 DUSP3 Dual specificity protein phosphatase 3 Hydrolase P51452
TCMT2 MAPT Microtubule-associated protein tau Unclassified P10636
TCMT206 CYP2A6 Cytochrome P450 2A6 Oxidoreductase P11509
TCMT207 BACE1 Beta-secretase 1 Protease P56817
TCMT212 SRC Tyrosine-protein kinase SRC Kinase P12931
TCMT214 MGLL Monoglyceride lipase Unclassified Q99685
TCMT215 CYP1A1 Cytochrome P450 1A1 Oxidoreductase P04798
TCMT218 CYP2B6 Cytochrome P450 2B6 Oxidoreductase P20813
TCMT219 CYP1A2 Cytochrome P450 1A2 Oxidoreductase P05177
TCMT223 AKR1B1 Aldose reductase Oxidoreductase P15121
TCMT230 HSD17B3 Estradiol 17-beta-dehydrogenase 3 Oxidoreductase P37058
TCMT232 ABCB1 P-glycoprotein 1 Transporter P08183
TCMT239 PIM1 Serine/threonine-protein kinase PIM1 Kinase P11309
TCMT240 AMY1A Salivary alpha-amylase Unclassified P04745
TCMT248 CXCL8 Interleukin-8 Unclassified P10145
TCMT249 CDK6 Cyclin-dependent kinase 6 Kinase Q00534
TCMT254 CBR1 Carbonyl reductase [NADPH] 1 Oxidoreductase P16152
TCMT257 CYP1B1 Cytochrome P450 1B1 Oxidoreductase Q16678
TCMT260 FLT3 Tyrosine-protein kinase receptor FLT3 Kinase P36888
TCMT261 DAPK1 Death-associated protein kinase 1 Kinase P53355
TCMT265 GSK3B Glycogen synthase kinase-3 beta Kinase P49841
TCMT276 SLCO2B1 Solute carrier organic anion transporter family member 2B1 Transporter O94956
TCMT277 SLCO1B3 Solute carrier organic anion transporter family member 1B3 Transporter Q9NPD5
TCMT278 SLCO1B1 Solute carrier organic anion transporter family member 1B1 Transporter Q9Y6L6
TCMT280 AKR1B10 Aldo-keto reductase family 1 member B10 Oxidoreductase O60218
TCMT283 PTPRS Receptor-type tyrosine-protein phosphatase S Hydrolase Q13332
TCMT297 FABP4 Fatty acid binding protein adipocyte Unclassified P15090
TCMT298 FABP3 Fatty acid binding protein muscle Hydrolase P05413
TCMT3 ALOX15 Arachidonate 15-lipoxygenase Oxidoreductase P16050
TCMT30 PTGS2 Cyclooxygenase-2 Oxidoreductase P35354
TCMT307 KCNH2 HERG Ion channel Q12809
TCMT31 CYP2C19 Cytochrome P450 2C19 Oxidoreductase P33261
TCMT327 TRPV1 Vanilloid receptor Ion channel Q8NER1
TCMT33 CYP3A4 Cytochrome P450 3A4 Oxidoreductase P08684
TCMT34 CYP2D6 Cytochrome P450 2D6 Oxidoreductase P10635
TCMT377 INSR Insulin receptor Kinase P06213
TCMT384 GRK6 G protein-coupled receptor kinase 6 Kinase P43250
TCMT39 PDE5A Phosphodiesterase 5A Hydrolase O76074
TCMT41 IDH1 Isocitrate dehydrogenase [NADP] cytoplasmic Oxidoreductase O75874
TCMT42 KMT2A Histone-lysine N-methyltransferase MLL Transferase Q03164
TCMT423 EGFR Epidermal growth factor receptor erbB1 Kinase P00533
TCMT44 GLO1 Glyoxalase I Lyase Q04760
TCMT45 APP Beta amyloid A4 protein Unclassified P05067
TCMT46 F3 Coagulation factor III Unclassified P13726
TCMT508 SYK Tyrosine-protein kinase SYK Kinase P43405
TCMT558 TOP2A DNA topoisomerase II alpha Isomerase P11388
TCMT559 ADRB2 Beta-2 adrenergic receptor GPCR P07550
TCMT592 XDH Xanthine dehydrogenase Oxidoreductase P47989
TCMT6 NFKB1 Nuclear factor NF-kappa-B p105 subunit Transcription factor P19838
TCMT63 PPARA Peroxisome proliferator-activated receptor alpha Nuclear receptor Q07869
TCMT64 PPARD Peroxisome proliferator-activated receptor delta Nuclear receptor Q03181
TCMT65 HSD17B1 Estradiol 17-beta-dehydrogenase 1 Oxidoreductase P14061
TCMT66 HSD17B2 Estradiol 17-beta-dehydrogenase 2 Oxidoreductase P37059
TCMT67 PPARG Peroxisome proliferator-activated receptor gamma Nuclear receptor P37231
TCMT69 THRB Thyroid hormone receptor beta-1 Nuclear receptor P10828
TCMT739 GPR35 G-protein coupled receptor 35 GPCR Q9HC97
TCMT747 ABCG2 ATP-binding cassette sub-family G member 2 Transporter Q9UNQ0
TCMT752 CSNK2A1 Casein kinase II alpha Kinase P68400
TCMT8 KDM4E Lysine-specific demethylase 4D-like Oxidoreductase B2RXH2
TCMT80 MAPK1 MAP kinase ERK2 Kinase P28482
TCMT801 TUBB3 Tubulin beta-3 chain Unclassified Q13509
TCMT81 ALOX12 Arachidonate 12-lipoxygenase Oxidoreductase P18054
TCMT82 ESR1 Estrogen receptor alpha Nuclear receptor P03372
TCMT87 CYP2C9 Cytochrome P450 2C9 Oxidoreductase P11712


Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1090 Human immunodeficiency virus type 1 integrase
TCMT1094 3-oxoacyl-acyl-carrier protein reductase
TCMT1099 Neuraminidase
TCMT1176 Streptococcus pneumoniae
TCMT1191 Bacillus megaterium
TCMT1214 Enterococcus faecium
TCMT1217 Bacillus anthracis
TCMT1218 Staphylococcus aureus
TCMT1226 Klebsiella pneumoniae
TCMT1229 Enterococcus faecalis
TCMT1232 Pseudomonas aeruginosa
TCMT1236 Mycobacterium bovis
TCMT1246 Escherichia coli
TCMT1249 Dengue virus 2
TCMT1251 Candida albicans
TCMT1260 Streptococcus agalactiae
TCMT1286 Bacillus cereus
TCMT1319 Corynebacterium xerosis
TCMT1322 Streptococcus mitis
TCMT1323 Corynebacterium pseudodiphtheriticum
TCMT1324 Corynebacterium diphtheriae
TCMT1346 Helicobacter pylori
TCMT1349 Helicobacter pylori SS1
TCMT1410 Listeria monocytogenes
TCMT1412 Salmonella typhimurium
TCMT1438 Plasmodium falciparum
TCMT1439 Mycobacterium smegmatis
TCMT1442 Leishmania donovani
TCMT1448 Enterobacter aerogenes
TCMT1449 Influenza A virus
TCMT1454 Bacillus subtilis
TCMT1455 Mycobacterium tuberculosis H37Rv
TCMT1458 Filobasidiella neoformans
TCMT1462 Streptococcus mutans
TCMT1464 Hepatitis B virus
TCMT1465 Entamoeba histolytica

Ingredient Structrues

Ingredient ID: TCMC937
Formula: C18H20O5

Ingredient ID: TCMC908
Formula: C15H10O4

Ingredient ID: TCMC897
Formula: C16H18O9

Ingredient ID: TCMC841
Formula: C10H10O

Ingredient ID: TCMC756
Formula: C21H18O11

Ingredient ID: TCMC755
Formula: C15H10O5

Ingredient ID: TCMC710
Formula: C15H10O5

Ingredient ID: TCMC614
Formula: C29H36O15

Ingredient ID: TCMC606
Formula: C16H12O5

Ingredient ID: TCMC534
Formula: C16H14O5

Ingredient ID: TCMC522
Formula: C15H10O5

Ingredient ID: TCMC519
Formula: C21H20O10

Ingredient ID: TCMC417
Formula: C15H10O5

Ingredient ID: TCMC24
Formula: C15H14O6

Ingredient ID: TCMC2324
Formula: C10H16

Ingredient ID: TCMC2292
Formula: C16H12O6

Ingredient ID: TCMC2237
Formula: C16H12O5

Ingredient ID: TCMC2188
Formula: C17H14O7

Ingredient ID: TCMC2138
Formula: C16H12O4

Ingredient ID: TCMC2055
Formula: C21H18O12

Ingredient ID: TCMC2054
Formula: C15H10O6

Ingredient ID: TCMC1965
Formula: C21H20O9

Ingredient ID: TCMC1901
Formula: C15H14O2

Ingredient ID: TCMC1798
Formula: C16H12O5

Ingredient ID: TCMC1788
Formula: C18H34O2

Ingredient ID: TCMC1495
Formula: C18H32O2

Ingredient ID: TCMC1173
Formula: C10H10O4

Ingredient ID: TCMC1123
Formula: C15H12O6

Properties

Ingredient ID Formulae Name MW AlogP MlogP XlogP # HBA # HBD PSA # Rotatable Bond # Ring # Heacy Atom Lipinski RO5 Violation
TCMC24 C15H14O6 (+)-Epicatechin 290.08 -2.494 2.45 0.406 1 5 110.38 6 3 21 0
TCMC417 C15H10O5 3',4',7-Trihydroxyflavon 270.05 -1.8845 2.56 1.996 1 3 86.99 4 3 20 0
TCMC519 C21H20O10 5,6-Dihydroxy-2-Phenyl-7-[(2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(Hydroxymethyl)Oxan-2-Yl]Oxychromen-4-One 432.11 -3.6314 2.67 1.521 6 6 166.14 10 4 31 1
TCMC522 C15H10O5 5,7-Dihydroxy-2-(2-Hydroxyphenyl)Chromen-4-One 270.05 -1.8845 2.56 1.778 1 3 86.99 4 3 20 0
TCMC534 C16H14O5 5,7-Dihydroxy-6-Methoxy-2-Phenyl-2,3-Dihydrochromen-4-One 286.08 -1.4059 2.67 2.049 1 2 75.99 5 3 21 0
TCMC606 C16H12O5 Acacetin 284.07 -1.476 2.67 2.086 1 2 75.99 5 3 21 0
TCMC614 C29H36O15 Acetoside 624.21 -4.2978 3 -0.202 11 9 245.29 21 4 44 3
TCMC710 C15H10O5 Apigenin 270.05 -1.8845 2.56 1.567 1 3 86.99 4 3 20 0
TCMC755 C15H10O5 Baicalein 270.05 -1.8845 2.56 3.058 1 3 86.99 4 3 20 0
TCMC756 C21H18O11 Baicalin 446.08 -3.5292 2.56 1.678 7 6 183.21 10 4 32 1
TCMC841 C10H10O Butenone 146.07 0.1072 2.45 4.166 1 0 17.07 3 1 11 0
TCMC897 C16H18O9 Chlorogenic Acid 354.1 -2.1962 2.23 -0.447 7 6 164.75 11 2 25 1
TCMC908 C15H10O4 Chrysin 254.06 -1.4242 2.67 3.163 1 2 66.76 3 3 19 0
TCMC937 C18H20O5 Combretastatin A4 316.13 -0.1997 2.89 3.375 0 1 57.15 11 2 23 0
TCMC1123 C15H12O6 Eriodictyol 288.06 -2.2747 2.45 0.363 1 4 107.22 5 3 21 0
TCMC1173 C10H10O4 Ferulic Acid 194.06 -0.3908 2.12 1.231 2 2 66.76 6 1 14 0
TCMC1495 C18H32O2 Linoleic Acid 280.24 -0.9485 3.22 7.865 2 1 37.3 16 0 20 2
TCMC1788 C18H34O2 Oleic Acid 282.26 -2.3427 3.22 8.192 2 1 37.3 17 0 20 2
TCMC1798 C16H12O5 Oroxylin A 284.07 -1.476 2.67 2.719 1 2 75.99 5 3 21 0
TCMC1901 C15H14O2 Pinosylvin Methyl Ether 226.1 -0.0443 2.89 5.973 0 1 29.46 5 2 17 1
TCMC1965 C21H20O9 Puerarin 416.11 -3.823 2.78 0.4 6 6 156.91 9 4 30 1
TCMC2054 C15H10O6 Scutellarein 286.05 -2.3448 2.45 1.462 1 4 107.22 5 3 21 0
TCMC2055 C21H18O12 Scutellarin 462.08 -3.9895 2.45 0.082 7 7 203.44 11 4 33 1
TCMC2138 C16H12O4 Techtochrysin 268.07 -1.0157 2.78 3.682 1 1 55.76 4 3 20 0
TCMC2188 C17H14O7 Tricin 330.07 -1.9881 2.56 0.679 1 3 105.45 8 3 24 0
TCMC2237 C16H12O5 Wogonin 284.07 -1.476 2.67 2.719 1 2 75.99 5 3 21 0
TCMC2292 C16H12O6 4'-Hydroxywogonin 300.06 -1.9363 2.56 1.123 1 3 96.22 6 3 22 0
TCMC2324 C10H16 Limonene 136.13 2.1424 2.56 3.729 0 0 0 3 1 10 0

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