| GO Term |
GO Name |
Enriched Genes |
Log10 Adjusted P-value |
|
[BP] GO:0065008 |
regulation of biological quality
|
ABCG2, ACHE, ADORA1, ADRA1A, ADRA2A, AKR1B1, APEX1, APP, AR, AURKB, AXL, BCL2, CA12, CA2, CA7, CACNA1C, CNR1, CNR2, CYP19A1, CYP1A1, CYP1B1, CYP3A4, DRD1, DRD2, DRD3, EGFR, ESR1, F10, F2, F3, FABP3, FABP4, FLT3, GPR35, HMGCR, HSD17B1, HSD17B2, HSD17B3, HSPA1A, HTR1A, HTR2A, HTR2B, HTR2C, HTR7, INSR, KCNH2, KDR, MAOA, MET, MIF, MTNR1B, POLA1, POLB, PPARA, SLC6A2, SLC6A4, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
16.3761 |
|
[BP] GO:0010647 |
positive regulation of cell communication
|
ADORA1, ADRA1A, ADRA2A, AKR1B1, APP, AR, AXL, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, EGFR, F10, F2, F3, FLT3, GPR35, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, INSR, KDR, MAP2K1, MAP3K7, MET, MIF, MMP12, MMP9, PTPN1, RELA, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
15.7594 |
|
[BP] GO:0042221 |
response to chemical
|
ABCG2, ADRA1A, ADRA2A, AKR1B1, ALPL, APEX1, APP, AR, AXL, BCL2, CA2, CA3, CA9, CES1, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DRD3, EGFR, ESR1, ESRRA, FABP3, FABP4, FLT3, HMGCR, HSD17B2, HSPA1A, HTR2A, HTR2B, HTR2C, HTR5A, IGF1R, INSR, KCNH2, KDR, MMP2, MMP9, POLB, PPARA, PTGES, RELA, RORC, SLC6A2, SLC6A4, SMAD3, SRC, TEK, TERT, TYR |
15.7594 |
|
[BP] GO:0023056 |
positive regulation of signaling
|
ADORA1, ADRA1A, ADRA2A, AKR1B1, APP, AR, AXL, BCL2, CA2, CA7, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, EGFR, F10, F2, F3, FLT3, GPR35, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, INSR, KDR, MAP2K1, MAP3K7, MET, MIF, MMP12, MMP9, PTPN1, RELA, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
15.7584 |
|
[BP] GO:0042127 |
regulation of cell proliferation
|
ADORA1, ADORA3, ADRA1A, ADRA2A, AKR1B1, APP, AR, BCL2, CDC25B, CSNK2A1, CYP1B1, DRD2, DRD3, EGFR, ESR1, ESRRA, F2, F3, FABP3, FLT3, HMGCR, HSPA1A, HTR1A, HTR2A, HTR2B, IGF1R, INSR, KDR, MAP2K1, MIF, MMP12, MMP2, MMP9, NUAK1, PIM1, PTGES, RELA, SLC6A4, SMAD3, SRC, TEK, TERT, XDH |
14.2853 |
|
[BP] GO:0009967 |
positive regulation of signal transduction
|
ADORA1, ADRA1A, ADRA2A, AKR1B1, APP, AR, AXL, BCL2, CSNK2A1, CYP1B1, DRD2, DRD3, EGFR, F10, F2, F3, FLT3, GPR35, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, INSR, KDR, MAP2K1, MAP3K7, MET, MIF, MMP12, MMP9, PTPN1, RELA, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
13.8453 |
|
[BP] GO:1901700 |
response to oxygen-containing compound
|
AKR1B1, ALPL, APEX1, APP, AR, AXL, BCL2, CA3, CA9, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DRD3, EGFR, ESR1, ESRRA, FABP3, HMGCR, HSD17B2, HTR5A, IGF1R, INSR, MMP2, MMP9, POLB, PPARA, PTGES, RELA, RORC, SLC6A4, SRC, TEK, TYR |
13.8107 |
|
[BP] GO:1902533 |
positive regulation of intracellular signal transduction
|
ADORA1, ADRA1A, ADRA2A, AKR1B1, APP, AR, AXL, BCL2, CYP1B1, DRD2, EGFR, F10, F2, F3, FLT3, GPR35, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, INSR, KDR, MAP2K1, MAP3K7, MET, MIF, PTPN1, RELA, SRC, TEK, XDH |
13.105 |
|
[BP] GO:0010646 |
regulation of cell communication
|
ACHE, ADORA1, ADRA1A, ADRA2A, AKR1B1, APP, AR, AURKB, AXL, BCL2, CA2, CA7, CACNA1C, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, F10, F2, F3, FLT3, GPR35, HMGCR, HSPA1A, HTR1A, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, MAP2K1, MAP3K7, MET, MIF, MMP12, MMP9, MTNR1B, NUAK1, PTPN1, RELA, SLC6A4, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
12.943 |
|
[BP] GO:0010033 |
response to organic substance
|
ADRA1A, ADRA2A, AKR1B1, ALPL, APEX1, APP, AR, AXL, BCL2, CA2, CA3, CA9, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DRD3, EGFR, ESR1, ESRRA, FABP3, FABP4, FLT3, HMGCR, HSD17B2, HSPA1A, HTR5A, IGF1R, INSR, KDR, MMP2, POLB, PPARA, PTGES, RELA, RORC, SLC6A4, SMAD3, SRC, TEK, TYR |
12.943 |
|
[BP] GO:0023051 |
regulation of signaling
|
ACHE, ADORA1, ADRA1A, ADRA2A, AKR1B1, APP, AR, AURKB, AXL, BCL2, CA2, CA7, CACNA1C, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, F10, F2, F3, FLT3, GPR35, HMGCR, HSPA1A, HTR1A, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, MAP2K1, MAP3K7, MET, MIF, MMP12, MMP9, MTNR1B, NUAK1, PTPN1, RELA, SLC6A4, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
12.7456 |
|
[BP] GO:0050896 |
response to stimulus
|
ABCG2, ACHE, ADORA1, ADORA3, ADRA1A, ADRA2A, AKR1B1, ALPL, APEX1, APP, AR, AURKB, AXL, BCL2, CA2, CA3, CA6, CA9, CES1, CHRM2, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DRD3, EGFR, ESR1, ESRRA, F10, F2, F3, FABP3, FABP4, FLT3, HMGCR, HSD17B2, HSPA1A, HTR1A, HTR2A, HTR2B, HTR2C, HTR5A, IGF1R, INSR, KCNH2, KDR, MAP2K1, MAP3K7, MIF, MMP12, MMP2, MMP9, NUAK1, POLA1, POLB, PPARA, PTGES, PTPN1, RELA, RORC, SLC6A2, SLC6A4, SMAD3, SRC, TEK, TERT, TOP2A, TYR |
12.2168 |
|
[BP] GO:0042493 |
response to drug
|
ABCG2, ADRA1A, AKR1B1, APEX1, AXL, BCL2, CA3, CA9, CNR1, CNR2, CYP1A1, CYP1B1, DRD1, DRD2, DRD3, EGFR, FABP3, HMGCR, HTR2A, HTR2B, HTR2C, KCNH2, KDR, POLB, RELA, SLC6A2, SLC6A4, SRC |
12.0556 |
|
[BP] GO:0015701 |
bicarbonate transport
|
CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9 |
12.0556 |
|
[BP] GO:0048584 |
positive regulation of response to stimulus
|
ADORA1, ADRA1A, ADRA2A, AKR1B1, APP, AR, AXL, BCL2, CNR1, CSNK2A1, CYP1B1, DRD2, DRD3, EGFR, ESRRA, F10, F2, F3, FABP4, FLT3, GPR35, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, INSR, KDR, MAP2K1, MAP3K7, MET, MIF, MMP12, MMP2, MMP9, PTPN1, RELA, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
11.7157 |
|
[BP] GO:0042592 |
homeostatic process
|
ABCG2, ADORA1, ADRA1A, ADRA2A, AKR1B1, APEX1, APP, AXL, BCL2, CA12, CA2, CA7, CACNA1C, CNR1, DRD1, DRD2, DRD3, EGFR, ESR1, F2, FABP3, FABP4, FLT3, GPR35, HTR2A, HTR2B, HTR2C, INSR, KCNH2, MET, MTNR1B, POLA1, POLB, SMAD3, SRC, TERT |
11.6656 |
|
[BP] GO:0044281 |
small molecule metabolic process
|
ABCG2, AKR1B1, AKR1B10, ALOX5, AOX1, APP, CA1, CA12, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CES1, CES2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, CYP3A4, FABP3, FUT7, GLO1, HMGCR, HSD17B3, HSPA1A, HTR2B, HTR2C, MIF, PIM1, PPARA, PTGES, TBXAS1, TYR, XDH |
11.6161 |
|
[BP] GO:1902531 |
regulation of intracellular signal transduction
|
ADORA1, ADRA1A, ADRA2A, AKR1B1, APP, AR, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, DRD2, DRD3, DUSP3, EGFR, ESR1, F10, F2, F3, FLT3, GPR35, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, MAP2K1, MAP3K7, MET, MIF, MMP9, NUAK1, PTPN1, RELA, SRC, TEK, XDH |
11.5436 |
|
[BP] GO:0048522 |
positive regulation of cellular process
|
ACHE, ADORA1, ADRA1A, ADRA2A, AKR1B1, APEX1, APP, AR, AURKB, AXL, BCL2, CA2, CA7, CDC25B, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F2, F3, FABP3, FLT3, GPR35, HMGCR, HSPA1A, HTR1A, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KCNH2, KDR, MAP2K1, MAP3K7, MET, MIF, MMP1, MMP12, MMP2, MMP9, MTNR1A, PIM1, PPARA, PTPN1, RELA, RORC, SLC6A4, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
11.5436 |
|
[BP] GO:0014070 |
response to organic cyclic compound
|
ALPL, APEX1, APP, AR, BCL2, CA2, CA9, CNR1, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DRD3, EGFR, ESR1, ESRRA, FLT3, HTR5A, PTGES, RELA, RORC, SLC6A4, SRC, TEK, TYR |
11.3978 |
|
[BP] GO:0006730 |
one-carbon metabolic process
|
CA1, CA12, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9 |
11.3741 |
|
[BP] GO:0032844 |
regulation of homeostatic process
|
ADORA1, ADRA2A, AURKB, BCL2, CA2, CA7, CACNA1C, CNR1, DRD1, DRD2, DRD3, EGFR, F2, HMGCR, HTR2A, HTR2B, HTR2C, KDR, MIF, SRC, TNKS, TNKS2 |
10.706 |
|
[BP] GO:0008284 |
positive regulation of cell proliferation
|
ADRA2A, AKR1B1, AR, BCL2, CDC25B, CSNK2A1, DRD2, DRD3, EGFR, ESR1, F2, F3, FLT3, HMGCR, HTR1A, HTR2A, HTR2B, IGF1R, INSR, KDR, MIF, MMP12, MMP2, MMP9, PIM1, RELA, TEK, TERT |
10.2662 |
|
[BP] GO:0032879 |
regulation of localization
|
ACHE, ADORA1, ADORA3, ADRA2A, APEX1, APP, AR, AXL, BCL2, CA2, CA7, CACNA1C, CNR1, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, EGFR, F10, F2, F3, GPR35, HMGCR, HSPA1A, HTR1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KCNH2, KDR, MAP2K1, MET, MIF, MMP12, MMP9, MTNR1B, PPARA, PTPN1, SLC6A4, SMAD3, SRC, TEK, TERT |
10.2017 |
|
[BP] GO:0032501 |
multicellular organismal process
|
ADORA1, ADRA1A, ADRA2A, AKR1B1, AKR1B10, ALOX5, ALPL, APP, AR, AXL, BCL2, CACNA1C, CNR1, CNR2, CYP19A1, CYP1A2, CYP1B1, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESRRB, F10, F2, F3, FABP4, HMGCR, HSD17B2, HTR1A, HTR2A, HTR2B, HTR2C, HTR7, IGF1R, INSR, KCNH2, MET, MMP1, MMP12, MMP2, MMP9, PIM1, PPARA, RELA, RORC, SLC6A2, SLC6A4, SMAD3, SRC, TEK, TNKS2, TYR |
10.1436 |
|
[BP] GO:0009636 |
response to toxic substance
|
AKR1B1, ALPL, APEX1, AXL, BCL2, CA3, CES1, CNR1, CNR2, CYP1A1, CYP1B1, DRD1, DRD2, DRD3, HMGCR, KDR, POLB, RELA, SLC6A4, SRC |
10.1033 |
|
[BP] GO:0007187 |
None
|
ADORA1, ADRA1A, ADRA2A, CHRM2, CNR1, CNR2, DRD1, DRD2, DRD3, HTR1A, HTR5A, HTR6, HTR7, MTNR1A, MTNR1B |
10.0673 |
|
[BP] GO:0044237 |
cellular metabolic process
|
ABCG2, ACHE, AKR1B1, AKR1B10, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CA1, CA12, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CDC25B, CES1, CES2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, CYP3A4, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F2, FABP3, FABP4, FLT3, FUT7, GLO1, HMGCR, HSD17B1, HSD17B2, HSD17B3, HSPA1A, HTR1A, HTR2B, HTR2C, IGF1R, INSR, KCNH2, KDR, MAOA, MAP2K1, MAP3K7, MET, MIF, MMP1, MMP2, NUAK1, PIM1, POLA1, POLB, PPARA, PTGES, PTPN1, RELA, RORC, SLC6A4, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
9.96589 |
|
[BP] GO:0048878 |
chemical homeostasis
|
ABCG2, ADRA1A, ADRA2A, AKR1B1, APP, BCL2, CA12, CA2, CA7, CACNA1C, CNR1, DRD1, DRD2, DRD3, EGFR, ESR1, F2, FABP3, FABP4, GPR35, HTR2A, HTR2B, HTR2C, INSR, KCNH2, MET, MTNR1B, SMAD3 |
9.65042 |
|
[BP] GO:0008152 |
metabolic process
|
ABCG2, ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CA1, CA12, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CDC25B, CES1, CES2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, CYP3A4, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F2, F3, FABP3, FABP4, FLT3, FUT7, GLO1, HMGCR, HSD17B1, HSD17B2, HSD17B3, HSPA1A, HTR1A, HTR2B, HTR2C, IGF1R, INSR, KCNH2, KDR, MAOA, MAP2K1, MAP3K7, MET, MIF, MMP1, MMP12, MMP2, MMP9, NUAK1, PIM1, POLA1, POLB, PPARA, PTGES, PTPN1, RELA, RORC, SLC6A4, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
9.64781 |
|
[BP] GO:0010562 |
positive regulation of phosphorus metabolic process
|
ADORA1, ADRA1A, ADRA2A, APP, AR, BCL2, CDC25B, DRD1, DRD2, EGFR, ESRRB, F2, FABP3, FLT3, HMGCR, HTR2A, HTR2B, HTR2C, INSR, KDR, MAP2K1, MAP3K7, MIF, MMP9, MTNR1A, PTPN1, SMAD3, SRC, TEK, XDH |
9.64468 |
|
[BP] GO:0045937 |
positive regulation of phosphate metabolic process
|
ADORA1, ADRA1A, ADRA2A, APP, AR, BCL2, CDC25B, DRD1, DRD2, EGFR, ESRRB, F2, FABP3, FLT3, HMGCR, HTR2A, HTR2B, HTR2C, INSR, KDR, MAP2K1, MAP3K7, MIF, MMP9, MTNR1A, PTPN1, SMAD3, SRC, TEK, XDH |
9.64468 |
|
[BP] GO:0006629 |
lipid metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, APP, CES1, CES2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, CYP3A4, DRD2, EGFR, ESR1, FABP3, FABP4, FUT7, HMGCR, HSD17B1, HSD17B2, HSD17B3, MET, MIF, PPARA, PTGES, TBXAS1 |
9.43217 |
|
[BP] GO:0048518 |
positive regulation of biological process
|
ACHE, ADORA1, ADRA1A, ADRA2A, AKR1B1, APEX1, APP, AR, AURKB, AXL, BCL2, CA2, CA7, CDC25B, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F2, F3, FABP3, FABP4, FLT3, GPR35, HMGCR, HSPA1A, HTR1A, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KCNH2, KDR, MAP2K1, MAP3K7, MET, MIF, MMP1, MMP12, MMP2, MMP9, MTNR1A, PIM1, PPARA, PTPN1, RELA, RORC, SLC6A4, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
9.42144 |
|
[BP] GO:0008202 |
steroid metabolic process
|
AKR1B1, AKR1B10, APP, CES1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, CYP3A4, ESR1, HMGCR, HSD17B1, HSD17B2, HSD17B3 |
9.42144 |
|
[BP] GO:0009719 |
response to endogenous stimulus
|
ADRA1A, ADRA2A, AKR1B1, ALPL, APEX1, APP, AR, BCL2, CA2, CA9, CSNK2A1, CYP1A2, DRD1, EGFR, ESR1, ESRRA, FABP3, FLT3, HTR5A, IGF1R, INSR, MMP2, PPARA, RELA, SLC6A4, SMAD3, SRC, TEK |
9.31057 |
|
[BP] GO:0010817 |
regulation of hormone levels
|
ACHE, ADORA1, ADRA2A, AKR1B1, CACNA1C, CNR1, CYP19A1, CYP1A1, CYP1B1, CYP3A4, DRD2, EGFR, ESR1, HMGCR, HSD17B1, HSD17B2, HSD17B3, HTR1A, HTR2A, HTR2C, MTNR1B |
9.30716 |
|
[BP] GO:0043410 |
positive regulation of MAPK cascade
|
ADORA1, ADRA1A, ADRA2A, APP, AR, DRD2, EGFR, FLT3, HMGCR, HTR2A, HTR2B, HTR2C, INSR, KDR, MAP2K1, MAP3K7, MIF, PTPN1, SRC, TEK, XDH |
9.2829 |
|
[BP] GO:0043067 |
regulation of programmed cell death
|
ADORA1, AKR1B1, APEX1, AR, AURKB, AXL, BCL2, CNR1, CSNK2A1, CYP1B1, EGFR, ESR1, F3, FLT3, GLO1, HMGCR, HSPA1A, HTR2B, IGF1R, KDR, MAP2K1, MET, MIF, MMP9, PIM1, PTPN1, RELA, SIGMAR1, SMAD3, SRC, TEK, TERT, TOP2A, XDH |
9.03537 |
|
[BP] GO:0033993 |
response to lipid
|
ALPL, AR, AXL, BCL2, CA2, CA9, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, EGFR, ESR1, ESRRA, FABP3, FLT3, HSD17B2, HTR5A, PTGES, RELA, RORC, SLC6A4, SRC, TYR |
9.0264 |
|
[BP] GO:0009725 |
response to hormone
|
ADRA1A, ADRA2A, AKR1B1, ALPL, APEX1, AR, BCL2, CA2, CA9, CSNK2A1, CYP1A2, EGFR, ESR1, ESRRA, FABP3, FLT3, HTR5A, INSR, PPARA, RELA, SLC6A4, SRC, TEK |
8.96226 |
|
[BP] GO:0032502 |
developmental process
|
ACHE, ADORA1, ADRA1A, AKR1B1, ALPL, APEX1, APP, AR, AURKB, AXL, BCL2, CA2, CA9, CACNA1C, CDC25B, CES1, CHRM2, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DUSP3, EGFR, ESR1, ESRRA, ESRRB, F2, FABP4, FLT3, FUT7, GLO1, HMGCR, HSD17B2, HSD17B3, HTR2A, HTR2B, HTR5A, INSR, KDR, MAP2K1, MET, MIF, MMP2, MMP9, PIM1, POLB, PPARA, RELA, RORC, SIGMAR1, SLC6A4, SMAD3, SRC, TEK, TERT, TNKS2, TOP2A, TYR |
8.91075 |
|
[BP] GO:0010941 |
regulation of cell death
|
ADORA1, AKR1B1, APEX1, AR, AURKB, AXL, BCL2, CNR1, CSNK2A1, CYP1B1, EGFR, ESR1, F3, FLT3, GLO1, HMGCR, HSPA1A, HTR2B, IGF1R, KDR, MAP2K1, MET, MIF, MMP9, PIM1, PPARA, PTPN1, RELA, SIGMAR1, SMAD3, SRC, TEK, TERT, TOP2A, XDH |
8.86912 |
|
[BP] GO:0019220 |
regulation of phosphate metabolic process
|
ADORA1, ADRA1A, ADRA2A, APP, AR, BCL2, CDC25B, DRD1, DRD2, DRD3, DUSP3, EGFR, ESRRB, F2, FABP3, FABP4, FLT3, HMGCR, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MAP2K1, MAP3K7, MIF, MMP9, MTNR1A, NUAK1, PPARA, PTPN1, SMAD3, SRC, TEK, XDH |
8.85485 |
|
[BP] GO:0007165 |
signal transduction
|
ADORA1, ADORA3, ADRA1A, ADRA2A, AKR1B1, APP, AR, AXL, BCL2, CA1, CA2, CACNA1C, CHRM2, CNR1, CNR2, CSNK2A1, CYP1B1, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FLT3, GPR35, HTR1A, HTR2A, HTR2B, HTR2C, HTR5A, HTR6, HTR7, IGF1R, INSR, KCNH2, KDR, MAP2K1, MAP3K7, MET, MIF, MMP2, MMP9, MTNR1A, MTNR1B, NUAK1, PIM1, POLB, PPARA, PTGES, PTPN1, RELA, RORC, SIGMAR1, SMAD3, SRC, TEK, TNKS, TNKS2 |
8.82361 |
|
[BP] GO:0051174 |
regulation of phosphorus metabolic process
|
ADORA1, ADRA1A, ADRA2A, APP, AR, BCL2, CDC25B, DRD1, DRD2, DRD3, DUSP3, EGFR, ESRRB, F2, FABP3, FABP4, FLT3, HMGCR, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MAP2K1, MAP3K7, MIF, MMP9, MTNR1A, NUAK1, PPARA, PTPN1, SMAD3, SRC, TEK, XDH |
8.77462 |
|
[BP] GO:0003018 |
None
|
ADORA1, ADRA1A, ADRA2A, DRD1, EGFR, HMGCR, HTR1A, HTR2A, HTR2B, HTR7, SLC6A4, SRC, TEK |
8.74806 |
|
[BP] GO:0051173 |
positive regulation of nitrogen compound metabolic process
|
ADORA1, ADRA1A, ADRA2A, APP, AR, AURKB, BCL2, CDC25B, CSNK2A1, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FLT3, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MAP2K1, MAP3K7, MET, MIF, MMP12, MMP9, MTNR1A, PPARA, PTPN1, RELA, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
8.74222 |
|
[BP] GO:0048523 |
negative regulation of cellular process
|
ACHE, ADORA1, ADORA3, ADRA1A, ADRA2A, AKR1B1, APEX1, APP, AR, AURKB, AXL, BCL2, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, CYP2D6, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, FABP3, FABP4, GLO1, GPR35, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, KCNH2, KDR, MAP2K1, MET, MIF, MMP12, MMP9, PIM1, PPARA, PTGES, PTPN1, RELA, RORC, SLC6A4, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
8.59213 |
|
[BP] GO:0042981 |
regulation of apoptotic process
|
ADORA1, AKR1B1, APEX1, AR, AURKB, AXL, BCL2, CNR1, CSNK2A1, CYP1B1, EGFR, ESR1, F3, FLT3, GLO1, HMGCR, HSPA1A, HTR2B, IGF1R, KDR, MAP2K1, MIF, MMP9, PIM1, PTPN1, RELA, SIGMAR1, SMAD3, SRC, TEK, TERT, TOP2A, XDH |
8.52637 |
|
[BP] GO:2000021 |
regulation of ion homeostasis
|
ADORA1, BCL2, CA2, CA7, CACNA1C, DRD1, DRD2, DRD3, F2, HTR2A, HTR2B, HTR2C, KDR, SRC |
8.33598 |
|
[BP] GO:0043408 |
regulation of MAPK cascade
|
ADORA1, ADRA1A, ADRA2A, APP, AR, DRD2, DUSP3, EGFR, FLT3, HMGCR, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MAP2K1, MAP3K7, MIF, PTPN1, SRC, TEK, XDH |
8.32358 |
|
[BP] GO:0031325 |
positive regulation of cellular metabolic process
|
ADORA1, ADRA1A, ADRA2A, APP, AR, AURKB, BCL2, CDC25B, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FABP3, FLT3, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MAP2K1, MAP3K7, MET, MIF, MMP12, MMP9, MTNR1A, PPARA, PTPN1, RELA, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
8.21347 |
|
[BP] GO:0010648 |
negative regulation of cell communication
|
ACHE, ADORA1, ADRA1A, ADRA2A, AR, BCL2, CNR2, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, GPR35, HMGCR, HSPA1A, HTR2A, IGF1R, MET, MIF, MMP12, MMP9, PTPN1, RELA, SLC6A4, SMAD3, SRC, TERT, XDH |
8.19968 |
|
[BP] GO:0009893 |
positive regulation of metabolic process
|
ADORA1, ADRA1A, ADRA2A, APP, AR, AURKB, BCL2, CDC25B, CSNK2A1, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FABP3, FLT3, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MAP2K1, MAP3K7, MET, MIF, MMP12, MMP9, MTNR1A, PPARA, PTPN1, RELA, RORC, SLC6A4, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
8.19968 |
|
[BP] GO:0023057 |
negative regulation of signaling
|
ACHE, ADORA1, ADRA1A, ADRA2A, AR, BCL2, CNR2, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, GPR35, HMGCR, HSPA1A, HTR2A, IGF1R, MET, MIF, MMP12, MMP9, PTPN1, RELA, SLC6A4, SMAD3, SRC, TERT, XDH |
8.17324 |
|
[BP] GO:0010604 |
positive regulation of macromolecule metabolic process
|
ADORA1, ADRA1A, ADRA2A, APP, AR, AURKB, BCL2, CDC25B, CSNK2A1, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FLT3, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MAP2K1, MAP3K7, MET, MIF, MMP12, MMP9, PPARA, PTPN1, RELA, RORC, SLC6A4, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
8.15518 |
|
[BP] GO:0051049 |
regulation of transport
|
ACHE, ADORA1, ADRA2A, APP, AXL, BCL2, CA2, CA7, CACNA1C, CNR1, CYP19A1, DRD1, DRD2, DRD3, EGFR, F2, GPR35, HMGCR, HSPA1A, HTR1A, HTR2A, HTR2B, HTR2C, INSR, KCNH2, MAP2K1, MIF, MMP12, MMP9, MTNR1B, PPARA, PTPN1, SLC6A4, SMAD3, SRC, TERT |
8.13739 |
|
[BP] GO:0048583 |
regulation of response to stimulus
|
ADORA1, ADRA1A, ADRA2A, AKR1B1, APP, AR, AURKB, AXL, BCL2, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, F10, F2, F3, FABP4, FLT3, GPR35, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, MAP2K1, MAP3K7, MET, MIF, MMP12, MMP2, MMP9, NUAK1, PPARA, PTPN1, RELA, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
8.1067 |
|
[BP] GO:0009966 |
regulation of signal transduction
|
ADORA1, ADRA1A, ADRA2A, AKR1B1, APP, AR, AURKB, AXL, BCL2, CSNK2A1, CYP1B1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, F10, F2, F3, FLT3, GPR35, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, HTR6, IGF1R, INSR, KDR, MAP2K1, MAP3K7, MET, MIF, MMP12, MMP9, NUAK1, PTPN1, RELA, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, XDH |
8.04628 |
|
[BP] GO:0050790 |
regulation of catalytic activity
|
ADORA1, ADORA3, ADRA1A, ADRA2A, APP, AR, AURKB, BCL2, CDC25B, CNR1, CNR2, CSNK2A1, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, F2, F3, FABP4, FLT3, HMGCR, HSPA1A, HTR2A, HTR2B, IGF1R, INSR, MAP2K1, MAP3K7, MIF, MMP9, NUAK1, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, XDH |
8.00481 |
|
[BP] GO:0032845 |
None
|
ADORA1, ADRA2A, BCL2, DRD2, HMGCR, HTR2A, HTR2B, HTR2C, MIF, SRC, TNKS, TNKS2 |
8.00481 |
|
[BP] GO:0051239 |
regulation of multicellular organismal process
|
ADORA1, ADORA3, ADRA1A, ADRA2A, APP, AR, AXL, BCL2, CA2, CACNA1C, CHRM2, CNR1, CYP1B1, DRD2, DRD3, EGFR, ESR1, ESRRA, ESRRB, F2, F3, GPR35, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, INSR, KCNH2, KDR, MAP2K1, MAP3K7, MET, MIF, MMP12, MMP9, PIM1, RELA, SLC6A4, SMAD3, SRC, TEK, TERT, TNKS2, XDH |
8.00481 |
|
[BP] GO:0097756 |
None
|
ADORA1, ADRA1A, HMGCR, HTR1A, HTR2A, HTR2B, HTR7, SLC6A4 |
7.9226 |
|
[BP] GO:0042327 |
positive regulation of phosphorylation
|
ADORA1, ADRA1A, ADRA2A, APP, AR, BCL2, CDC25B, DRD2, EGFR, ESRRB, F2, FLT3, HMGCR, HTR2A, HTR2B, HTR2C, INSR, KDR, MAP2K1, MAP3K7, MIF, MMP9, PTPN1, SRC, TEK, XDH |
7.90858 |
|
[BP] GO:0070372 |
regulation of ERK1 and ERK2 cascade
|
ADRA1A, APP, DRD2, DUSP3, EGFR, HMGCR, HTR2A, HTR2B, HTR2C, KDR, MAP2K1, MIF, PTPN1, SRC, TEK |
7.90503 |
|
[BP] GO:0007210 |
None
|
HTR1A, HTR2A, HTR2B, HTR2C, HTR5A, HTR6, HTR7 |
7.90293 |
|
[BP] GO:0098664 |
None
|
HTR1A, HTR2A, HTR2B, HTR2C, HTR5A, HTR6, HTR7 |
7.90293 |
|
[BP] GO:0030334 |
regulation of cell migration
|
ADORA1, ADORA3, ADRA2A, APEX1, APP, BCL2, CYP19A1, CYP1B1, DRD1, DRD2, EGFR, F10, F3, IGF1R, INSR, KDR, MET, MIF, MMP9, SMAD3, SRC, TEK, TERT |
7.80749 |
|
[BP] GO:0051240 |
positive regulation of multicellular organismal process
|
ADRA1A, ADRA2A, APP, AR, AXL, BCL2, CA2, CNR1, CYP1B1, DRD2, DRD3, EGFR, ESRRB, F2, F3, HMGCR, HSPA1A, HTR2A, HTR2B, KDR, MAP2K1, MAP3K7, MET, MIF, MMP12, MMP9, PIM1, RELA, SMAD3, SRC, TEK, TERT |
7.77341 |
|
[BP] GO:0048511 |
rhythmic process
|
AXL, BCL2, CSNK2A1, DRD2, DRD3, EGFR, ESR1, HTR7, MTNR1A, MTNR1B, PPARA, RORC, SLC6A4, SRC, TOP2A |
7.72249 |
|
[BP] GO:0048513 |
animal organ development
|
ACHE, ADRA1A, AR, AXL, BCL2, CA2, CACNA1C, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, EGFR, ESR1, ESRRA, ESRRB, FLT3, HSD17B2, HSD17B3, INSR, KDR, MAP2K1, POLB, PPARA, RELA, SMAD3, SRC, TEK, TYR |
7.67414 |
|
[BP] GO:0070374 |
positive regulation of ERK1 and ERK2 cascade
|
ADRA1A, APP, DRD2, EGFR, HMGCR, HTR2A, HTR2B, HTR2C, KDR, MAP2K1, MIF, SRC, TEK |
7.63116 |
|
[BP] GO:0080134 |
regulation of response to stress
|
ADORA1, ADRA2A, APP, CNR1, CNR2, CYP19A1, DRD2, DUSP3, EGFR, ESR1, F2, F3, FABP4, HMGCR, HSPA1A, IGF1R, MAP2K1, MAP3K7, MET, MIF, MMP12, MMP2, NUAK1, PPARA, PTPN1, RELA, SMAD3, SRC, TEK, TERT, XDH |
7.63116 |
|
[BP] GO:0001934 |
positive regulation of protein phosphorylation
|
ADORA1, ADRA1A, ADRA2A, APP, AR, BCL2, CDC25B, DRD2, EGFR, F2, FLT3, HMGCR, HTR2A, HTR2B, HTR2C, INSR, KDR, MAP2K1, MAP3K7, MIF, MMP9, PTPN1, SRC, TEK, XDH |
7.61036 |
|
[BP] GO:0043069 |
negative regulation of programmed cell death
|
ADORA1, AKR1B1, AR, AURKB, AXL, BCL2, CSNK2A1, EGFR, GLO1, HMGCR, HSPA1A, HTR2B, IGF1R, KDR, MET, MIF, MMP9, PIM1, PTPN1, RELA, SMAD3, SRC, TEK, TERT |
7.60863 |
|
[BP] GO:0060548 |
negative regulation of cell death
|
ADORA1, AKR1B1, AR, AURKB, AXL, BCL2, CSNK2A1, EGFR, GLO1, HMGCR, HSPA1A, HTR2B, IGF1R, KDR, MET, MIF, MMP9, PIM1, PPARA, PTPN1, RELA, SMAD3, SRC, TEK, TERT |
7.57063 |
|
[BP] GO:0097746 |
None
|
ADORA1, ADRA1A, ADRA2A, DRD1, EGFR, HMGCR, HTR1A, HTR2A, HTR2B, HTR7, SLC6A4 |
7.56463 |
|
[BP] GO:0035296 |
None
|
ADORA1, ADRA1A, ADRA2A, DRD1, EGFR, HMGCR, HTR1A, HTR2A, HTR2B, HTR7, SLC6A4 |
7.56463 |
|
[BP] GO:0010035 |
response to inorganic substance
|
AKR1B1, APEX1, APP, AXL, BCL2, CA2, CYP1A1, CYP1A2, CYP1B1, DRD2, EGFR, FABP4, KDR, MMP9, PTGES, RELA, SRC, TERT |
7.53338 |
|
[BP] GO:0048585 |
negative regulation of response to stimulus
|
ADORA1, ADRA1A, ADRA2A, AR, BCL2, CNR1, CNR2, CYP19A1, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, F2, HMGCR, HSPA1A, IGF1R, MET, MIF, MMP12, MMP9, PPARA, PTPN1, RELA, SMAD3, SRC, TEK, TERT, XDH |
7.48403 |
|
[BP] GO:0065009 |
regulation of molecular function
|
ADORA1, ADORA3, ADRA1A, ADRA2A, APP, AR, AURKB, BCL2, CDC25B, CNR1, CNR2, CSNK2A1, CYP1B1, CYP2D6, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, F2, F3, FABP4, FLT3, GPR35, HMGCR, HSPA1A, HTR2A, HTR2B, IGF1R, INSR, MAP2K1, MAP3K7, MET, MIF, MMP9, NUAK1, PIM1, PPARA, PTPN1, RELA, SMAD3, SRC, TEK, TERT, TNKS, XDH |
7.45622 |
|
[BP] GO:0003013 |
None
|
ADORA1, ADRA1A, ADRA2A, DRD1, EGFR, HMGCR, HTR1A, HTR2A, HTR2B, HTR7, SLC6A4, SRC, TEK |
7.45575 |
|
[BP] GO:0040012 |
regulation of locomotion
|
ADORA1, ADORA3, ADRA2A, APEX1, APP, BCL2, CYP19A1, CYP1B1, DRD1, DRD2, DRD3, EGFR, F10, F3, IGF1R, INSR, KDR, MET, MIF, MMP9, SMAD3, SRC, TEK, TERT |
7.42421 |
|
[BP] GO:0050801 |
ion homeostasis
|
ABCG2, ADRA1A, APP, BCL2, CA12, CA2, CA7, CACNA1C, DRD1, DRD2, DRD3, EGFR, ESR1, F2, FABP3, GPR35, HTR2A, HTR2B, HTR2C, KCNH2, SMAD3 |
7.41655 |
|
[BP] GO:0051270 |
regulation of cellular component movement
|
ADORA1, ADORA3, ADRA2A, APEX1, APP, BCL2, CACNA1C, CYP19A1, CYP1B1, DRD1, DRD2, EGFR, F10, F3, IGF1R, INSR, KDR, MET, MIF, MMP9, SMAD3, SRC, TEK, TERT |
7.40228 |
|
[BP] GO:0033559 |
unsaturated fatty acid metabolic process
|
ALOX5, CES2, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, MIF, PTGES, TBXAS1 |
7.39336 |
|
[BP] GO:0042325 |
regulation of phosphorylation
|
ADORA1, ADRA1A, ADRA2A, APP, AR, BCL2, CDC25B, DRD1, DRD2, DUSP3, EGFR, ESRRB, F2, FABP4, FLT3, HMGCR, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MAP2K1, MAP3K7, MIF, MMP9, PPARA, PTPN1, SRC, TEK, XDH |
7.38857 |
|
[BP] GO:1901615 |
organic hydroxy compound metabolic process
|
AKR1B1, AKR1B10, APP, BCL2, CES1, CYP19A1, CYP1A1, CYP1B1, CYP3A4, DRD1, DRD2, DRD3, HMGCR, HSD17B3, HTR1A, MAOA, TYR |
7.38857 |
|
[BP] GO:2000145 |
regulation of cell motility
|
ADORA1, ADORA3, ADRA2A, APEX1, APP, BCL2, CYP19A1, CYP1B1, DRD1, DRD2, EGFR, F10, F3, IGF1R, INSR, KDR, MET, MIF, MMP9, SMAD3, SRC, TEK, TERT |
7.35011 |
|
[BP] GO:0050880 |
None
|
ADORA1, ADRA1A, ADRA2A, DRD1, EGFR, HMGCR, HTR1A, HTR2A, HTR2B, HTR7, SLC6A4 |
7.31995 |
|
[BP] GO:0019216 |
regulation of lipid metabolic process
|
ADORA1, ADRA2A, CNR1, CYP1A1, DRD3, F2, FABP3, FLT3, HMGCR, HTR2A, HTR2B, HTR2C, PPARA, RORC, SRC, TEK |
7.29607 |
|
[BP] GO:0035150 |
None
|
ADORA1, ADRA1A, ADRA2A, DRD1, EGFR, HMGCR, HTR1A, HTR2A, HTR2B, HTR7, SLC6A4 |
7.29171 |
|
[BP] GO:0009987 |
cellular process
|
ABCG2, ACHE, ADORA1, ADORA3, ADRA1A, ADRA2A, AKR1B1, AKR1B10, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CA1, CA12, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CACNA1C, CDC25B, CES1, CES2, CHRM2, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, CYP3A4, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F2, F3, FABP3, FABP4, FLT3, FUT7, GLO1, GPR35, HMGCR, HSD17B1, HSD17B2, HSD17B3, HSPA1A, HTR1A, HTR2A, HTR2B, HTR2C, HTR5A, HTR6, HTR7, IGF1R, INSR, KCNH2, KDR, MAOA, MAP2K1, MAP3K7, MET, MIF, MMP1, MMP12, MMP2, MMP9, MTNR1A, MTNR1B, NUAK1, PIM1, POLA1, POLB, PPARA, PTGES, PTPN1, RELA, RORC, SIGMAR1, SLC6A2, SLC6A4, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
7.21428 |
|
[BP] GO:0009628 |
response to abiotic stimulus
|
ADORA1, AKR1B1, APP, AURKB, BCL2, CA2, CYP1A1, DRD1, DRD2, DRD3, EGFR, HMGCR, HSPA1A, HTR2A, HTR2B, MMP2, POLB, PPARA, RELA, SLC6A4, SMAD3, SRC, TEK, TERT, TYR |
7.16052 |
|
[BP] GO:0006690 |
icosanoid metabolic process
|
ALOX5, CES2, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, MIF, PTGES, TBXAS1 |
7.12322 |
|
[BP] GO:0019748 |
secondary metabolic process
|
AKR1B1, AKR1B10, BCL2, CYP1A1, CYP1A2, CYP1B1, CYP2D6, TYR |
7.0834 |
|
[BP] GO:0032228 |
regulation of synaptic transmission, GABAergic
|
ADORA1, ADRA1A, CA2, CA7, CNR1, CNR2, DRD2 |
7.05957 |
|
[BP] GO:0043066 |
negative regulation of apoptotic process
|
ADORA1, AKR1B1, AR, AURKB, AXL, BCL2, CSNK2A1, EGFR, GLO1, HMGCR, HSPA1A, HTR2B, IGF1R, KDR, MIF, MMP9, PIM1, PTPN1, RELA, SMAD3, SRC, TEK, TERT |
7.05957 |
|
[BP] GO:0032101 |
regulation of response to external stimulus
|
ADORA1, CNR1, CNR2, CYP19A1, DRD1, DRD2, DRD3, EGFR, ESR1, F2, F3, FABP4, HMGCR, KDR, MAP2K1, MET, MIF, MMP12, PPARA, RELA, SMAD3, TEK |
7.00996 |
|
[BP] GO:0048519 |
negative regulation of biological process
|
ACHE, ADORA1, ADORA3, ADRA1A, ADRA2A, AKR1B1, APEX1, APP, AR, AURKB, AXL, BCL2, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1B1, CYP2D6, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, FABP3, FABP4, GLO1, GPR35, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, KCNH2, KDR, MAP2K1, MET, MIF, MMP12, MMP9, PIM1, PPARA, PTGES, PTPN1, RELA, RORC, SLC6A4, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
6.99817 |
|
[BP] GO:0001932 |
regulation of protein phosphorylation
|
ADORA1, ADRA1A, ADRA2A, APP, AR, BCL2, CDC25B, DRD1, DRD2, DUSP3, EGFR, F2, FABP4, FLT3, HMGCR, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MAP2K1, MAP3K7, MIF, MMP9, PTPN1, SRC, TEK, XDH |
6.98184 |
|
[BP] GO:0098771 |
inorganic ion homeostasis
|
ABCG2, ADRA1A, APP, BCL2, CA12, CA2, CA7, CACNA1C, DRD1, DRD2, DRD3, EGFR, ESR1, F2, GPR35, HTR2A, HTR2B, HTR2C, KCNH2, SMAD3 |
6.96562 |
|
[BP] GO:0007568 |
aging
|
ADRA1A, APEX1, AURKB, BCL2, CNR1, CYP1A1, HMGCR, HTR2A, MAP2K1, MIF, POLB, RELA, TERT |
6.89438 |
|
[BP] GO:0043405 |
regulation of MAP kinase activity
|
ADORA1, ADRA2A, DUSP3, EGFR, FLT3, HMGCR, HTR2A, HTR2B, IGF1R, INSR, MAP2K1, MAP3K7, MIF, PTPN1, SRC |
6.76889 |
|
[BP] GO:0051247 |
positive regulation of protein metabolic process
|
ADORA1, ADRA1A, ADRA2A, APP, AR, BCL2, CDC25B, CSNK2A1, DRD2, EGFR, ESR1, F2, F3, FLT3, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, INSR, KDR, MAP2K1, MAP3K7, MIF, MMP9, PTPN1, RELA, SMAD3, SRC, TEK, XDH |
6.66436 |
|
[BP] GO:0007188 |
None
|
ADORA1, ADRA1A, ADRA2A, CHRM2, CNR1, DRD1, DRD2, DRD3, HTR1A, HTR5A, HTR7 |
6.59985 |
|
[BP] GO:0007200 |
None
|
ADRA1A, ADRA2A, CHRM2, DRD1, DRD2, ESR1, HTR2A, HTR2B, HTR2C |
6.56244 |
|
[BP] GO:0043269 |
regulation of ion transport
|
ADORA1, ADRA2A, APP, BCL2, CA2, CA7, CACNA1C, CNR1, DRD1, DRD2, DRD3, F2, GPR35, HTR1A, HTR2A, KCNH2, MIF, MMP9, SLC6A4 |
6.55868 |
|
[BP] GO:0044093 |
positive regulation of molecular function
|
ADORA1, ADRA1A, ADRA2A, APP, AR, AURKB, BCL2, CDC25B, DRD2, EGFR, ESR1, ESR2, F2, F3, FLT3, HSPA1A, HTR2A, HTR2B, INSR, MAP2K1, MAP3K7, MET, MIF, MMP9, PTPN1, RELA, SMAD3, SRC, TEK, TERT, TNKS, XDH |
6.52427 |
|
[BP] GO:0050804 |
modulation of chemical synaptic transmission
|
ACHE, ADORA1, ADRA1A, APP, CA2, CA7, CNR1, CNR2, DRD1, DRD2, DRD3, EGFR, HTR2A, SLC6A4 |
6.51401 |
|
[BP] GO:0099177 |
regulation of trans-synaptic signaling
|
ACHE, ADORA1, ADRA1A, APP, CA2, CA7, CNR1, CNR2, DRD1, DRD2, DRD3, EGFR, HTR2A, SLC6A4 |
6.51401 |
|
[BP] GO:0006796 |
phosphate-containing compound metabolic process
|
ACHE, ALPL, APEX1, APP, AURKB, AXL, BCL2, CA3, CDC25B, CSNK2A1, DRD1, DRD2, DUSP3, EGFR, FLT3, HMGCR, HSPA1A, HTR2B, HTR2C, IGF1R, INSR, KCNH2, KDR, MAP2K1, MAP3K7, MET, NUAK1, PIM1, POLB, PTPN1, SRC, TEK, TNKS, XDH |
6.4862 |
|
[BP] GO:0051716 |
cellular response to stimulus
|
ADRA2A, AKR1B1, ALPL, APEX1, APP, AR, AURKB, AXL, BCL2, CA2, CA9, CYP1A1, CYP1A2, CYP1B1, DRD1, EGFR, ESR1, FABP4, FLT3, HSPA1A, IGF1R, INSR, KCNH2, KDR, MAP2K1, MAP3K7, MIF, MMP2, MMP9, NUAK1, POLA1, POLB, PTPN1, RELA, RORC, SLC6A4, SMAD3, SRC, TERT, TOP2A |
6.46605 |
|
[BP] GO:0031399 |
regulation of protein modification process
|
ADORA1, ADRA1A, ADRA2A, APP, AR, BCL2, CDC25B, DRD1, DRD2, DUSP3, EGFR, F2, FABP4, FLT3, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MAP2K1, MAP3K7, MIF, MMP9, NUAK1, PTPN1, RELA, SRC, TEK, XDH |
6.39016 |
|
[BP] GO:0055080 |
cation homeostasis
|
ABCG2, ADRA1A, APP, BCL2, CA2, CA7, CACNA1C, DRD1, DRD2, DRD3, EGFR, ESR1, F2, GPR35, HTR2A, HTR2B, HTR2C, KCNH2, SMAD3 |
6.36147 |
|
[BP] GO:0007186 |
G-protein coupled receptor signaling pathway
|
ADORA1, ADORA3, ADRA1A, ADRA2A, APP, CA2, CHRM2, CNR1, CNR2, DRD1, DRD2, DRD3, ESR1, F2, GPR35, HTR1A, HTR2A, HTR2B, HTR2C, HTR5A, HTR6, HTR7, INSR, MTNR1A, MTNR1B, SIGMAR1, SRC |
6.35695 |
|
[BP] GO:0070887 |
cellular response to chemical stimulus
|
ADRA2A, AKR1B1, ALPL, APEX1, APP, AR, AXL, BCL2, CYP1A1, CYP1A2, CYP1B1, DRD1, EGFR, ESR1, FABP4, FLT3, HSPA1A, IGF1R, INSR, KCNH2, KDR, MMP2, MMP9, RELA, RORC, SLC6A4, SMAD3, SRC, TERT |
6.30927 |
|
[BP] GO:1903727 |
positive regulation of phospholipid metabolic process
|
FABP3, FLT3, HTR2A, HTR2B, HTR2C, SRC, TEK |
6.18449 |
|
[BP] GO:0009891 |
positive regulation of biosynthetic process
|
APP, AR, AURKB, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, FABP3, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MAP2K1, MET, MMP12, MTNR1A, PPARA, RELA, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A |
6.18449 |
|
[BP] GO:0030335 |
positive regulation of cell migration
|
ADRA2A, APP, BCL2, DRD1, EGFR, F10, F3, IGF1R, INSR, KDR, MET, MMP9, SMAD3, SRC, TEK, TERT |
6.17305 |
|
[BP] GO:0044255 |
cellular lipid metabolic process
|
ACHE, AKR1B10, ALOX5, CES1, CES2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, CYP3A4, DRD2, EGFR, FABP3, FABP4, FUT7, HMGCR, MET, MIF, PPARA, PTGES, TBXAS1 |
6.14426 |
|
[BP] GO:0030522 |
intracellular receptor signaling pathway
|
AR, ESR1, ESR2, ESRRA, ESRRB, MAP3K7, PIM1, PPARA, RELA, RORC, SRC |
6.13472 |
|
[BP] GO:0032270 |
positive regulation of cellular protein metabolic process
|
ADORA1, ADRA1A, ADRA2A, APP, AR, BCL2, CDC25B, DRD2, EGFR, ESR1, F2, F3, FLT3, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, INSR, KDR, MAP2K1, MAP3K7, MIF, MMP9, PTPN1, SMAD3, SRC, TEK, XDH |
6.03818 |
|
[BP] GO:0006793 |
phosphorus metabolic process
|
ACHE, ALPL, APEX1, APP, AURKB, AXL, BCL2, CA3, CDC25B, CSNK2A1, DRD1, DRD2, DUSP3, EGFR, FLT3, HMGCR, HSPA1A, HTR2B, HTR2C, IGF1R, INSR, KCNH2, KDR, MAP2K1, MAP3K7, MET, NUAK1, PIM1, POLB, PTPN1, SRC, TEK, TNKS, XDH |
6.02926 |
|
[BP] GO:2000147 |
positive regulation of cell motility
|
ADRA2A, APP, BCL2, DRD1, EGFR, F10, F3, IGF1R, INSR, KDR, MET, MMP9, SMAD3, SRC, TEK, TERT |
5.97616 |
|
[BP] GO:0043271 |
negative regulation of ion transport
|
ADORA1, ADRA2A, BCL2, CNR1, DRD2, DRD3, GPR35, HTR2A, KCNH2, MMP9 |
5.9465 |
|
[BP] GO:1901564 |
organonitrogen compound metabolic process
|
ABCG2, ACHE, AKR1B1, ALPL, AOX1, APP, AR, AURKB, AXL, BCL2, CDC25B, CSNK2A1, CYP1A1, CYP1A2, CYP2D6, CYP3A4, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, F10, F2, F3, FLT3, FUT7, GLO1, HMGCR, HSPA1A, HTR1A, HTR2B, HTR2C, IGF1R, INSR, KCNH2, KDR, MAOA, MAP2K1, MAP3K7, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIM1, POLB, PPARA, PTPN1, RELA, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A, TYR, XDH |
5.90625 |
|
[BP] GO:1903530 |
regulation of secretion by cell
|
ACHE, ADORA1, ADRA2A, CACNA1C, CNR1, CYP19A1, DRD2, DRD3, EGFR, HMGCR, HTR1A, HTR2A, HTR2B, HTR2C, MIF, MMP12, MTNR1B, SLC6A4, SRC |
5.82789 |
|
[BP] GO:0051272 |
positive regulation of cellular component movement
|
ADRA2A, APP, BCL2, DRD1, EGFR, F10, F3, IGF1R, INSR, KDR, MET, MMP9, SMAD3, SRC, TEK, TERT |
5.81719 |
|
[BP] GO:0010243 |
response to organonitrogen compound
|
AKR1B1, APEX1, APP, CNR1, CNR2, DRD1, DRD2, DRD3, EGFR, FABP3, FLT3, IGF1R, INSR, MMP2, PPARA, RELA, SLC6A4, SRC, TEK, TYR |
5.81719 |
|
[BP] GO:0034754 |
cellular hormone metabolic process
|
AKR1B1, CYP19A1, CYP1A1, CYP1B1, CYP3A4, ESR1, HSD17B1, HSD17B2, HSD17B3 |
5.81719 |
|
[BP] GO:0007193 |
None
|
ADORA1, ADRA2A, CHRM2, DRD2, DRD3, HTR1A, HTR5A, HTR7 |
5.80117 |
|
[BP] GO:0042310 |
None
|
ADRA1A, HTR1A, HTR2A, HTR2B, HTR7, SLC6A4 |
5.77543 |
|
[BP] GO:0051338 |
regulation of transferase activity
|
ADORA1, ADRA2A, APP, AURKB, CDC25B, DRD2, DUSP3, EGFR, F2, FABP4, FLT3, HMGCR, HTR2A, HTR2B, IGF1R, INSR, MAP2K1, MAP3K7, MIF, PTPN1, SRC, TEK, TNKS |
5.7732 |
|
[BP] GO:0055065 |
metal ion homeostasis
|
ABCG2, ADRA1A, APP, BCL2, CACNA1C, DRD1, DRD2, DRD3, EGFR, ESR1, F2, GPR35, HTR2A, HTR2B, HTR2C, KCNH2, SMAD3 |
5.76371 |
|
[BP] GO:0043549 |
regulation of kinase activity
|
ADORA1, ADRA2A, APP, CDC25B, DRD2, DUSP3, EGFR, F2, FABP4, FLT3, HMGCR, HTR2A, HTR2B, IGF1R, INSR, MAP2K1, MAP3K7, MIF, PTPN1, SRC, TEK |
5.75822 |
|
[BP] GO:0016098 |
monoterpenoid metabolic process
|
CYP1A2, CYP2C19, CYP2D6, CYP3A4 |
5.72922 |
|
[BP] GO:0018958 |
None
|
AKR1B1, BCL2, DRD1, DRD2, DRD3, HTR1A, MAOA, TYR |
5.72922 |
|
[BP] GO:0006468 |
protein phosphorylation
|
APP, AURKB, AXL, BCL2, CDC25B, CSNK2A1, DRD1, EGFR, FLT3, HTR2B, IGF1R, INSR, KCNH2, KDR, MAP2K1, MAP3K7, MET, NUAK1, PIM1, SRC, TEK, TNKS |
5.72922 |
|
[BP] GO:0006631 |
fatty acid metabolic process
|
ALOX5, CES1, CES2, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, FABP3, MIF, PPARA, PTGES, TBXAS1 |
5.72922 |
|
[BP] GO:0072507 |
divalent inorganic cation homeostasis
|
ADRA1A, APP, BCL2, CACNA1C, DRD1, DRD2, DRD3, EGFR, ESR1, F2, GPR35, HTR2A, HTR2B, HTR2C, SMAD3 |
5.69312 |
|
[BP] GO:0015711 |
organic anion transport
|
CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, DRD2, DRD3, FABP3, PPARA |
5.69312 |
|
[BP] GO:0031401 |
positive regulation of protein modification process
|
ADORA1, ADRA1A, ADRA2A, APP, AR, BCL2, CDC25B, DRD2, EGFR, F2, FLT3, HMGCR, HTR2A, HTR2B, HTR2C, INSR, KDR, MAP2K1, MAP3K7, MIF, MMP9, PTPN1, SRC, TEK, XDH |
5.69191 |
|
[BP] GO:0006805 |
xenobiotic metabolic process
|
CES1, CES2, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, CYP3A4, RORC |
5.64881 |
|
[BP] GO:0040017 |
positive regulation of locomotion
|
ADRA2A, APP, BCL2, DRD1, EGFR, F10, F3, IGF1R, INSR, KDR, MET, MMP9, SMAD3, SRC, TEK, TERT |
5.64881 |
|
[BP] GO:1901568 |
fatty acid derivative metabolic process
|
ALOX5, CES2, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, MIF, PTGES, TBXAS1 |
5.61028 |
|
[BP] GO:0048856 |
anatomical structure development
|
ACHE, ADORA1, ADRA1A, AKR1B1, ALPL, APP, AR, AXL, BCL2, CA2, CACNA1C, CHRM2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, DUSP3, EGFR, ESR1, ESRRA, ESRRB, F2, FLT3, HSD17B2, HSD17B3, HTR5A, INSR, KDR, MAP2K1, MMP9, PIM1, POLB, PPARA, RELA, RORC, SIGMAR1, SMAD3, SRC, TEK, TYR |
5.57581 |
|
[BP] GO:0019369 |
arachidonic acid metabolic process
|
CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, PTGES, TBXAS1 |
5.56129 |
|
[BP] GO:0043085 |
positive regulation of catalytic activity
|
ADORA1, ADRA1A, ADRA2A, APP, AURKB, BCL2, CDC25B, DRD2, EGFR, ESR1, F2, F3, FLT3, HSPA1A, HTR2A, HTR2B, INSR, MAP2K1, MAP3K7, MIF, PTPN1, SMAD3, SRC, TEK, TERT, TNKS, XDH |
5.56129 |
|
[BP] GO:0030003 |
cellular cation homeostasis
|
ABCG2, ADRA1A, APP, BCL2, CA2, CA7, CACNA1C, DRD1, DRD2, DRD3, ESR1, F2, GPR35, HTR2A, HTR2B, HTR2C, SMAD3 |
5.55437 |
|
[BP] GO:0051050 |
positive regulation of transport
|
ACHE, ADORA1, ADRA2A, APP, AXL, BCL2, CA2, CYP19A1, DRD1, DRD2, DRD3, EGFR, F2, HTR2B, INSR, KCNH2, MIF, MMP12, SLC6A4, SMAD3, SRC, TERT |
5.54239 |
|
[BP] GO:0035556 |
intracellular signal transduction
|
ADRA1A, ADRA2A, AKR1B1, AXL, BCL2, CACNA1C, CYP1B1, DRD1, DRD2, DRD3, EGFR, HTR2A, HTR2B, HTR5A, IGF1R, INSR, KCNH2, KDR, MAP2K1, MAP3K7, MET, MIF, NUAK1, POLB, PTPN1, RELA, SRC, TEK |
5.52766 |
|
[BP] GO:0001505 |
regulation of neurotransmitter levels
|
ACHE, CYP1B1, DRD1, DRD2, DRD3, EGFR, HTR1A, INSR, MAOA, SLC6A2, SLC6A4, SMAD3 |
5.52766 |
|
[BP] GO:0045787 |
positive regulation of cell cycle
|
APEX1, APP, AURKB, CDC25B, CYP1A1, DRD2, DRD3, DUSP3, EGFR, INSR, MIF, SLC6A4, SRC, TERT |
5.50571 |
|
[BP] GO:0006950 |
response to stress
|
ACHE, ADORA1, ADORA3, AKR1B1, APEX1, APP, AXL, BCL2, CA2, CA3, CA9, CNR2, CYP1A1, CYP1A2, CYP1B1, DRD1, DRD2, EGFR, F2, HSPA1A, HTR1A, HTR2C, MAP2K1, MAP3K7, MIF, MMP2, MMP9, NUAK1, POLA1, POLB, PPARA, PTGES, PTPN1, RELA, SLC6A2, SLC6A4, SMAD3, SRC, TEK, TERT, TOP2A |
5.50089 |
|
[BP] GO:0071704 |
organic substance metabolic process
|
ABCG2, ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CDC25B, CES1, CES2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, CYP3A4, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F2, F3, FABP3, FABP4, FLT3, FUT7, GLO1, HMGCR, HSD17B1, HSD17B2, HSD17B3, HSPA1A, HTR1A, HTR2B, HTR2C, IGF1R, INSR, KCNH2, KDR, MAOA, MAP2K1, MAP3K7, MET, MIF, MMP1, MMP12, MMP2, MMP9, NUAK1, PIM1, POLA1, POLB, PPARA, PTGES, PTPN1, RELA, RORC, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
5.4639 |
|
[BP] GO:0090087 |
None
|
ACHE, ADORA1, ADRA2A, APP, CA2, CACNA1C, CNR1, DRD2, DRD3, EGFR, F2, HMGCR, HTR2B, HTR2C, MIF, MMP12, MTNR1B, PTPN1, SMAD3, SRC |
5.41997 |
|
[BP] GO:0006873 |
cellular ion homeostasis
|
ABCG2, ADRA1A, APP, BCL2, CA2, CA7, CACNA1C, DRD1, DRD2, DRD3, ESR1, F2, GPR35, HTR2A, HTR2B, HTR2C, SMAD3 |
5.41997 |
|
[BP] GO:0051046 |
None
|
ACHE, ADORA1, ADRA2A, CACNA1C, CNR1, CYP19A1, DRD2, DRD3, EGFR, HMGCR, HTR1A, HTR2A, HTR2B, HTR2C, MIF, MMP12, MTNR1B, SLC6A4, SRC |
5.40662 |
|
[BP] GO:0051896 |
regulation of protein kinase B signaling
|
AXL, DRD2, DRD3, EGFR, F10, F3, INSR, MET, SRC, TEK, XDH |
5.40453 |
|
[BP] GO:0045834 |
positive regulation of lipid metabolic process
|
F2, FABP3, FLT3, HTR2A, HTR2B, HTR2C, PPARA, SRC, TEK |
5.40173 |
|
[BP] GO:0046883 |
regulation of hormone secretion
|
ADORA1, ADRA2A, CACNA1C, CNR1, CYP19A1, DRD2, EGFR, HMGCR, HTR1A, HTR2A, HTR2C, MTNR1B |
5.40121 |
|
[BP] GO:0044092 |
negative regulation of molecular function
|
ADORA3, ADRA2A, APP, AURKB, CNR1, CNR2, CSNK2A1, CYP1B1, CYP2D6, DRD2, DRD3, DUSP3, ESR1, FABP4, GPR35, HMGCR, IGF1R, MET, MMP9, PIM1, PPARA, PTPN1, SRC, TNKS |
5.38729 |
|
[BP] GO:0043406 |
positive regulation of MAP kinase activity
|
ADORA1, ADRA2A, EGFR, FLT3, HTR2A, HTR2B, INSR, MAP2K1, MAP3K7, MIF, PTPN1, SRC |
5.38729 |
|
[BP] GO:0006874 |
cellular calcium ion homeostasis
|
ADRA1A, APP, BCL2, CACNA1C, DRD1, DRD2, DRD3, ESR1, F2, GPR35, HTR2A, HTR2B, HTR2C, SMAD3 |
5.38729 |
|
[BP] GO:1901698 |
response to nitrogen compound
|
AKR1B1, APEX1, APP, CNR1, CNR2, DRD1, DRD2, DRD3, EGFR, FABP3, FLT3, IGF1R, INSR, MMP2, PPARA, RELA, SLC6A4, SRC, TEK, TYR |
5.35845 |
|
[BP] GO:0006720 |
isoprenoid metabolic process
|
AKR1B10, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, CYP3A4, EGFR, HMGCR |
5.35514 |
|
[BP] GO:1902532 |
negative regulation of intracellular signal transduction
|
ADRA1A, BCL2, DRD2, DRD3, DUSP3, ESR1, HMGCR, HSPA1A, IGF1R, MET, MIF, MMP9, PTPN1, RELA, SRC, XDH |
5.35514 |
|
[BP] GO:0002791 |
None
|
ACHE, ADORA1, ADRA2A, CACNA1C, CNR1, DRD2, DRD3, EGFR, HMGCR, HTR2B, HTR2C, MIF, MMP12, MTNR1B, SRC |
5.31504 |
|
[BP] GO:0031328 |
positive regulation of cellular biosynthetic process
|
APP, AR, AURKB, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, HTR2A, HTR2B, HTR2C, IGF1R, INSR, MAP2K1, MET, MMP12, MTNR1A, PPARA, RELA, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A |
5.3065 |
|
[BP] GO:0017144 |
drug metabolic process
|
ACHE, AKR1B1, AKR1B10, AOX1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, CYP3A4, DRD1, DRD2, DRD3, EGFR, HSPA1A, MAOA |
5.2393 |
|
[BP] GO:0055074 |
calcium ion homeostasis
|
ADRA1A, APP, BCL2, CACNA1C, DRD1, DRD2, DRD3, ESR1, F2, GPR35, HTR2A, HTR2B, HTR2C, SMAD3 |
5.23846 |
|
[BP] GO:0009892 |
negative regulation of metabolic process
|
ADORA1, ADRA2A, APEX1, APP, AR, AURKB, BCL2, CNR1, CNR2, CSNK2A1, CYP2D6, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, F2, FABP4, HMGCR, HSPA1A, HTR2B, IGF1R, KDR, MAP2K1, MET, MIF, MMP12, MMP9, PPARA, PTPN1, RELA, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, XDH |
5.23238 |
|
[BP] GO:0072503 |
cellular divalent inorganic cation homeostasis
|
ADRA1A, APP, BCL2, CACNA1C, DRD1, DRD2, DRD3, ESR1, F2, GPR35, HTR2A, HTR2B, HTR2C, SMAD3 |
5.17455 |
|
[BP] GO:0051347 |
positive regulation of transferase activity
|
ADORA1, ADRA2A, AURKB, CDC25B, DRD2, EGFR, F2, FLT3, HTR2A, HTR2B, INSR, MAP2K1, MAP3K7, MIF, PTPN1, SRC, TEK, TNKS |
5.16188 |
|
[BP] GO:0032102 |
negative regulation of response to external stimulus
|
ADORA1, CNR2, CYP19A1, DRD1, DRD2, DRD3, F2, HMGCR, MIF, PPARA, SMAD3, TEK |
5.15245 |
|
[BP] GO:0032846 |
positive regulation of homeostatic process
|
AURKB, CA2, CA7, CNR1, DRD1, DRD2, DRD3, EGFR, F2, TNKS, TNKS2 |
5.13826 |
|
[BP] GO:0007610 |
None
|
APP, BCL2, CNR1, DRD1, DRD2, DRD3, EGFR, HMGCR, HTR1A, HTR2A, HTR2B, HTR2C, INSR, MTNR1A, PPARA, SLC6A4 |
5.11922 |
|
[BP] GO:0050805 |
negative regulation of synaptic transmission
|
ACHE, ADORA1, CNR2, DRD1, DRD2, HTR2A, SLC6A4 |
5.10917 |
|
[BP] GO:0050795 |
None
|
ADORA1, CNR1, DRD2, DRD3, HTR1A, HTR2A, HTR2B |
5.10917 |
|
[BP] GO:0071310 |
cellular response to organic substance
|
ADRA2A, AKR1B1, ALPL, APEX1, APP, AR, AXL, BCL2, CYP1A1, CYP1B1, DRD1, EGFR, ESR1, FABP4, FLT3, IGF1R, INSR, KDR, MMP2, RELA, RORC, SLC6A4, SMAD3, SRC |
5.08377 |
|
[BP] GO:0045935 |
positive regulation of nucleobase-containing compound metabolic process
|
APP, AR, AURKB, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, HSPA1A, HTR2A, IGF1R, INSR, MAP2K1, MET, MMP12, MTNR1A, PPARA, PTPN1, RELA, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A |
5.07148 |
|
[BP] GO:0007623 |
circadian rhythm
|
DRD2, DRD3, EGFR, HTR7, MTNR1A, MTNR1B, PPARA, RORC, SLC6A4 |
5.07107 |
|
[BP] GO:0023052 |
None
|
ADORA1, ADRA1A, AR, CACNA1C, CHRM2, CNR1, DRD1, DRD2, DRD3, ESR2, HTR2A, HTR2C, HTR6, HTR7, KCNH2, MTNR1B, SLC6A2, TEK |
5.05887 |
|
[BP] GO:0033674 |
positive regulation of kinase activity
|
ADORA1, ADRA2A, CDC25B, DRD2, EGFR, F2, FLT3, HTR2A, HTR2B, INSR, MAP2K1, MAP3K7, MIF, PTPN1, SRC, TEK |
5.04716 |
|
[BP] GO:0019725 |
cellular homeostasis
|
ABCG2, ADRA1A, APEX1, APP, BCL2, CA2, CA7, CACNA1C, DRD1, DRD2, DRD3, ESR1, F2, GPR35, HTR2A, HTR2B, HTR2C, POLA1, SMAD3 |
4.99392 |
|
[BP] GO:0031347 |
regulation of defense response
|
ADORA1, CNR1, CNR2, CYP19A1, DRD2, EGFR, ESR1, F2, FABP4, HSPA1A, MAP3K7, MMP12, MMP2, PPARA, PTPN1, RELA, SMAD3, SRC, TEK |
4.9872 |
|
[BP] GO:0042445 |
hormone metabolic process
|
ACHE, AKR1B1, CYP19A1, CYP1A1, CYP1B1, CYP3A4, ESR1, HSD17B1, HSD17B2, HSD17B3 |
4.98477 |
|
[BP] GO:0070482 |
response to oxygen levels
|
ADORA1, BCL2, CYP1A1, DRD2, MMP2, POLB, PPARA, SLC6A4, SMAD3, SRC, TEK, TERT |
4.98477 |
|
[BP] GO:0071407 |
cellular response to organic cyclic compound
|
ALPL, APEX1, APP, AR, CYP1A1, CYP1B1, DRD1, EGFR, ESR1, FLT3, RORC, SLC6A4, SRC |
4.98477 |
|
[BP] GO:0045859 |
regulation of protein kinase activity
|
ADORA1, ADRA2A, APP, CDC25B, DRD2, DUSP3, EGFR, FABP4, FLT3, HMGCR, HTR2A, HTR2B, IGF1R, INSR, MAP2K1, MAP3K7, MIF, PTPN1, SRC |
4.97923 |
|
[BP] GO:0018108 |
peptidyl-tyrosine phosphorylation
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MAP2K1, MET, SRC, TEK |
4.96999 |
|
[BP] GO:0006875 |
cellular metal ion homeostasis
|
ABCG2, ADRA1A, APP, BCL2, CACNA1C, DRD1, DRD2, DRD3, ESR1, F2, GPR35, HTR2A, HTR2B, HTR2C, SMAD3 |
4.96999 |
|
[BP] GO:0071073 |
None
|
FABP3, HTR2A, HTR2B, HTR2C |
4.94645 |
|
[BP] GO:0018212 |
peptidyl-tyrosine modification
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MAP2K1, MET, SRC, TEK |
4.91034 |
|
[BP] GO:0055114 |
oxidation-reduction process
|
AKR1B1, AKR1B10, ALOX5, AOX1, APEX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, CYP3A4, HMGCR, HSD17B1, HSD17B2, HSD17B3, MAOA, TBXAS1, TYR, XDH |
4.81213 |
|
[BP] GO:1903725 |
regulation of phospholipid metabolic process
|
FABP3, FLT3, HTR2A, HTR2B, HTR2C, SRC, TEK |
4.79027 |
|
[BP] GO:0006721 |
terpenoid metabolic process
|
AKR1B10, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, CYP3A4, EGFR |
4.78727 |
|
[BP] GO:0071900 |
regulation of protein serine/threonine kinase activity
|
ADORA1, ADRA2A, DUSP3, EGFR, FLT3, HMGCR, HTR2A, HTR2B, IGF1R, INSR, MAP2K1, MAP3K7, MIF, PTPN1, SRC |
4.78025 |
|
[BP] GO:0055082 |
cellular chemical homeostasis
|
ABCG2, ADRA1A, APP, BCL2, CA2, CA7, CACNA1C, DRD1, DRD2, DRD3, ESR1, F2, GPR35, HTR2A, HTR2B, HTR2C, SMAD3 |
4.77754 |
|
[BP] GO:0046777 |
protein autophosphorylation
|
AURKB, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KDR, PIM1, SRC, TEK |
4.77608 |
|
[BP] GO:0019222 |
regulation of metabolic process
|
ACHE, ADORA1, ADORA3, ADRA1A, ADRA2A, APEX1, APP, AR, AURKB, BCL2, CA9, CDC25B, CNR1, CNR2, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FABP3, FABP4, FLT3, GLO1, HMGCR, HSPA1A, HTR1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MAP2K1, MAP3K7, MET, MIF, MMP12, MMP9, MTNR1A, NUAK1, PIM1, POLA1, PPARA, PTPN1, RELA, RORC, SLC6A4, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
4.77608 |
|
[BP] GO:0008283 |
cell proliferation
|
ACHE, AR, AURKB, BCL2, CYP1A1, EGFR, ESR1, FLT3, HTR1A, MAP2K1, MET, MIF, PIM1, POLA1, SRC, TEK, TYR |
4.7733 |
|
[BP] GO:0034614 |
cellular response to reactive oxygen species
|
AKR1B1, APEX1, AXL, CYP1B1, EGFR, MMP9, RELA, SRC |
4.76621 |
|
[BP] GO:0097267 |
omega-hydroxylase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1, CYP2C19 |
4.7473 |
|
[BP] GO:0007346 |
regulation of mitotic cell cycle
|
APEX1, APP, AURKB, BCL2, CDC25B, CYP1A1, DRD3, DUSP3, EGFR, HSPA1A, INSR, MAP2K1, PIM1, SMAD3, TERT, TNKS, TOP2A |
4.73176 |
|
[BP] GO:0009968 |
negative regulation of signal transduction
|
ADRA1A, ADRA2A, AR, BCL2, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, HMGCR, HSPA1A, IGF1R, MET, MIF, MMP12, MMP9, PTPN1, RELA, SMAD3, SRC, TERT, XDH |
4.72323 |
|
[BP] GO:0044238 |
primary metabolic process
|
ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CDC25B, CES1, CES2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, CYP3A4, DRD1, DRD2, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F2, F3, FABP3, FABP4, FLT3, FUT7, GLO1, HMGCR, HSD17B1, HSD17B2, HSD17B3, HSPA1A, HTR2B, HTR2C, IGF1R, INSR, KCNH2, KDR, MAP2K1, MAP3K7, MET, MIF, MMP1, MMP12, MMP2, MMP9, NUAK1, PIM1, POLA1, POLB, PPARA, PTGES, PTPN1, RELA, RORC, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
4.67677 |
|
[BP] GO:0051952 |
None
|
ADORA1, ADRA2A, CNR1, DRD1, DRD2, DRD3, HTR2A |
4.64791 |
|
[BP] GO:0001666 |
response to hypoxia
|
ADORA1, BCL2, CYP1A1, DRD2, MMP2, PPARA, SLC6A4, SMAD3, SRC, TEK, TERT |
4.61138 |
|
[BP] GO:0006811 |
None
|
ADRA1A, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CACNA1C, DRD1, DRD2, DRD3, FABP3, HTR2A, HTR2B, HTR2C, KCNH2, PPARA, SLC6A2, SLC6A4 |
4.60152 |
|
[BP] GO:0006939 |
None
|
ADRA1A, DRD1, DRD2, HTR2A, HTR2B, HTR7 |
4.58606 |
|
[BP] GO:0065007 |
biological regulation
|
ABCG2, ACHE, ADORA1, ADORA3, ADRA1A, ADRA2A, AKR1B1, APEX1, APP, AR, AURKB, AXL, BCL2, CA1, CA12, CA2, CA7, CA9, CACNA1C, CDC25B, CHRM2, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, CYP3A4, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F2, F3, FABP3, FABP4, FLT3, GLO1, GPR35, HMGCR, HSD17B1, HSD17B2, HSD17B3, HSPA1A, HTR1A, HTR2A, HTR2B, HTR2C, HTR5A, HTR6, HTR7, IGF1R, INSR, KCNH2, KDR, MAOA, MAP2K1, MAP3K7, MET, MIF, MMP1, MMP12, MMP2, MMP9, MTNR1A, MTNR1B, NUAK1, PIM1, POLA1, POLB, PPARA, PTGES, PTPN1, RELA, RORC, SIGMAR1, SLC6A2, SLC6A4, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
4.56942 |
|
[BP] GO:0032880 |
regulation of protein localization
|
ACHE, ADRA2A, APP, AR, BCL2, CACNA1C, CNR1, CSNK2A1, DRD2, DRD3, EGFR, F2, HMGCR, HTR2B, MIF, MMP12, MTNR1B, PTPN1, SMAD3, SRC, TERT |
4.53093 |
|
[BP] GO:0036293 |
response to decreased oxygen levels
|
ADORA1, BCL2, CYP1A1, DRD2, MMP2, PPARA, SLC6A4, SMAD3, SRC, TEK, TERT |
4.49281 |
|
[BP] GO:0031323 |
regulation of cellular metabolic process
|
ACHE, ADORA1, ADORA3, ADRA1A, ADRA2A, APEX1, APP, AR, AURKB, BCL2, CA9, CDC25B, CNR1, CSNK2A1, CYP1B1, CYP2D6, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FABP3, FABP4, FLT3, GLO1, HMGCR, HSPA1A, HTR1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MAP2K1, MAP3K7, MET, MIF, MMP12, MMP9, MTNR1A, NUAK1, PIM1, POLA1, PPARA, PTPN1, RELA, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
4.47844 |
|
[BP] GO:0050890 |
None
|
ADORA1, APP, CNR1, DRD1, DRD2, DRD3, EGFR, HMGCR, HTR2A, INSR, SLC6A4 |
4.41605 |
|
[BP] GO:0050806 |
positive regulation of synaptic transmission
|
ADORA1, ADRA1A, APP, CA2, CA7, DRD1, DRD2, EGFR |
4.41496 |
|
[BP] GO:0007154 |
None
|
ADORA1, ADRA1A, AR, AXL, BCL2, CACNA1C, CHRM2, CNR1, DRD1, DRD2, DRD3, ESR2, HTR2A, HTR2C, HTR6, HTR7, MTNR1B, SLC6A2, TEK |
4.39515 |
|
[BP] GO:0006820 |
anion transport
|
CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, DRD2, DRD3, FABP3, PPARA |
4.37839 |
|
[BP] GO:0032268 |
regulation of cellular protein metabolic process
|
ADORA1, ADRA1A, ADRA2A, APP, AR, BCL2, CDC25B, CSNK2A1, DRD1, DRD2, DUSP3, EGFR, ESR1, F2, F3, FABP4, FLT3, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MAP2K1, MAP3K7, MIF, MMP9, NUAK1, PTPN1, RELA, SMAD3, SRC, TEK, XDH |
4.34637 |
|
[BP] GO:0016310 |
phosphorylation
|
APP, AURKB, AXL, BCL2, CDC25B, CSNK2A1, DRD1, EGFR, FLT3, HTR2B, IGF1R, INSR, KCNH2, KDR, MAP2K1, MAP3K7, MET, NUAK1, PIM1, SRC, TEK, TNKS |
4.34533 |
|
[BP] GO:0007267 |
None
|
ADORA1, ADRA1A, AR, CHRM2, CNR1, DRD1, DRD2, DRD3, ESR2, HTR2A, HTR2C, HTR6, HTR7, MTNR1B, SLC6A2, TEK |
4.34103 |
|
[BP] GO:0018193 |
peptidyl-amino acid modification
|
AURKB, AXL, BCL2, CSNK2A1, DRD1, EGFR, F10, F2, FLT3, IGF1R, INSR, KDR, MAP2K1, MAP3K7, MET, SRC, TEK, TNKS, TOP2A |
4.33711 |
|
[BP] GO:0031348 |
negative regulation of defense response
|
ADORA1, CNR2, CYP19A1, DRD2, F2, MMP12, PPARA, SMAD3, TEK |
4.31315 |
|
[BP] GO:0022414 |
reproductive process
|
AKR1B1, ALPL, APP, AR, AXL, BCL2, CDC25B, CNR1, CYP19A1, CYP1A1, DRD1, EGFR, ESR1, ESRRB, HSD17B2, HSD17B3, INSR, MAP2K1, MMP2, MMP9, MTNR1A, SLC6A4, SRC, TOP2A |
4.31315 |
|
[BP] GO:0032787 |
None
|
ALOX5, CES1, CES2, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, FABP3, GLO1, MIF, PPARA, PTGES, TBXAS1 |
4.3071 |
|
[BP] GO:0006694 |
steroid biosynthetic process
|
AKR1B1, CES1, CYP19A1, CYP3A4, HMGCR, HSD17B1, HSD17B2, HSD17B3 |
4.29752 |
|
[BP] GO:0006979 |
response to oxidative stress
|
AKR1B1, APEX1, APP, AXL, BCL2, CA3, CYP1B1, EGFR, HSPA1A, MMP9, RELA, SRC |
4.29712 |
|
[BP] GO:0051726 |
regulation of cell cycle
|
APEX1, APP, AURKB, BCL2, CDC25B, CSNK2A1, CYP1A1, DRD2, DRD3, DUSP3, EGFR, HSPA1A, INSR, MAP2K1, MIF, PIM1, SLC6A4, SMAD3, SRC, TERT, TNKS, TOP2A |
4.26966 |
|
[BP] GO:0035265 |
organ growth
|
ADRA1A, AR, BCL2, CYP19A1, ESR1 |
4.25974 |
|
[BP] GO:0000302 |
response to reactive oxygen species
|
AKR1B1, APEX1, AXL, BCL2, CYP1B1, EGFR, MMP9, RELA, SRC |
4.25967 |
|
[BP] GO:0007198 |
None
|
HTR1A, HTR5A, HTR7 |
4.25924 |
|
[BP] GO:0032847 |
regulation of cellular pH reduction
|
BCL2, CA2, CA7 |
4.25924 |
|
[BP] GO:0051130 |
positive regulation of cellular component organization
|
APP, AR, AURKB, AXL, BCL2, CNR1, DRD2, DRD3, ESR1, HSPA1A, IGF1R, INSR, KDR, MAP2K1, MET, MMP1, MMP9, SMAD3, SRC, TEK, TNKS, TNKS2 |
4.24656 |
|
[BP] GO:0051480 |
regulation of cytosolic calcium ion concentration
|
ADRA1A, CACNA1C, DRD1, DRD2, ESR1, F2, GPR35, HTR2A, HTR2B, HTR2C, SMAD3 |
4.24656 |
|
[BP] GO:0050793 |
regulation of developmental process
|
APP, AR, AXL, BCL2, CA2, CNR1, CYP1B1, DRD2, DRD3, EGFR, ESR1, ESRRA, ESRRB, F2, F3, HMGCR, HTR2A, HTR2C, INSR, KDR, MAP2K1, MIF, NUAK1, PIM1, PPARA, RELA, RORC, SLC6A4, SMAD3, SRC, TEK, TERT, TNKS2, XDH |
4.23553 |
|
[BP] GO:0043401 |
steroid hormone mediated signaling pathway
|
AR, ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC, SRC |
4.21054 |
|
[BP] GO:0071902 |
positive regulation of protein serine/threonine kinase activity
|
ADORA1, ADRA2A, EGFR, FLT3, HTR2A, HTR2B, INSR, MAP2K1, MAP3K7, MIF, PTPN1, SRC |
4.20798 |
|
[BP] GO:0009611 |
response to wounding
|
ACHE, ADORA3, BCL2, CYP1A1, DRD2, EGFR, F2, PPARA, SMAD3 |
4.17001 |
|
[BP] GO:0003008 |
None
|
ADORA1, ADRA1A, ADRA2A, AKR1B1, APP, BCL2, CNR1, CNR2, CYP1B1, DRD1, DRD2, DRD3, EGFR, HMGCR, HTR1A, HTR2A, HTR2B, HTR7, INSR, KCNH2, SLC6A4, SRC, TEK, TYR |
4.16748 |
|
[BP] GO:0050708 |
None
|
ACHE, ADRA2A, CACNA1C, CNR1, DRD2, DRD3, EGFR, HMGCR, HTR2B, MIF, MMP12, MTNR1B, SRC |
4.14891 |
|
[BP] GO:0080090 |
regulation of primary metabolic process
|
ADORA1, ADORA3, ADRA1A, ADRA2A, APEX1, APP, AR, AURKB, BCL2, CA9, CDC25B, CNR1, CSNK2A1, CYP1A1, CYP1B1, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FABP3, FABP4, FLT3, GLO1, HMGCR, HSPA1A, HTR1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MAP2K1, MAP3K7, MET, MIF, MMP12, MMP9, MTNR1A, NUAK1, PIM1, POLA1, PPARA, PTPN1, RELA, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
4.13451 |
|
[BP] GO:0019932 |
second-messenger-mediated signaling
|
ADRA1A, ADRA2A, CACNA1C, DRD1, DRD2, DRD3, EGFR, HTR2B, HTR5A, KDR |
4.13351 |
|
[BP] GO:0007611 |
None
|
APP, CNR1, DRD1, DRD2, DRD3, EGFR, HMGCR, HTR2A, INSR, SLC6A4 |
4.13351 |
|
[BP] GO:0097164 |
None
|
ACHE, AKR1B1, AKR1B10, CSNK2A1, DRD1, DRD2, DRD3, HTR1A, MAOA |
4.12268 |
|
[BP] GO:0070201 |
None
|
ACHE, ADRA2A, APP, BCL2, CACNA1C, CNR1, DRD2, DRD3, EGFR, F2, HMGCR, HTR2B, MIF, MMP12, MTNR1B, PTPN1, SMAD3, SRC |
4.12229 |
|
[BP] GO:0009894 |
regulation of catabolic process
|
ADORA1, ADRA2A, APEX1, BCL2, CNR1, CSNK2A1, EGFR, ESRRB, HSPA1A, HTR2A, HTR2B, INSR, KDR, MAP3K7, MET, PPARA, PTPN1, RELA, SMAD3 |
4.11172 |
|
[BP] GO:0051966 |
regulation of synaptic transmission, glutamatergic
|
ADORA1, CNR1, DRD1, DRD2, EGFR, HTR2A |
4.11133 |
|
[BP] GO:0010863 |
positive regulation of phospholipase C activity
|
ADRA1A, EGFR, ESR1, HTR2A, HTR2B |
4.08032 |
|
[BP] GO:0031324 |
negative regulation of cellular metabolic process
|
ADRA2A, APEX1, APP, AR, AURKB, BCL2, CNR1, CSNK2A1, CYP2D6, DRD2, DRD3, DUSP3, ESR1, ESR2, ESRRA, F2, FABP4, HMGCR, HSPA1A, HTR2B, IGF1R, MET, MIF, MMP12, MMP9, PPARA, PTPN1, RELA, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, XDH |
4.07529 |
|
[BP] GO:0099536 |
None
|
CHRM2, CNR1, DRD1, DRD2, DRD3, HTR2A, HTR2C, HTR6, HTR7, MTNR1B, SLC6A2 |
4.07529 |
|
[BP] GO:0099537 |
None
|
CHRM2, CNR1, DRD1, DRD2, DRD3, HTR2A, HTR2C, HTR6, HTR7, MTNR1B, SLC6A2 |
4.07529 |
|
[BP] GO:0048732 |
gland development
|
AR, BCL2, CSNK2A1, CYP19A1, EGFR, INSR, MAP2K1, RELA, SMAD3, TYR |
4.03431 |
|
[BP] GO:0042446 |
hormone biosynthetic process
|
AKR1B1, CYP19A1, CYP3A4, HSD17B1, HSD17B2, HSD17B3 |
4.03431 |
|
[BP] GO:1901701 |
cellular response to oxygen-containing compound
|
AKR1B1, APEX1, APP, AR, AXL, CYP1B1, DRD1, EGFR, ESR1, IGF1R, INSR, MMP2, MMP9, RELA, RORC, SLC6A4, SRC |
4.01547 |
|
[BP] GO:0045860 |
positive regulation of protein kinase activity
|
ADORA1, ADRA2A, CDC25B, DRD2, EGFR, FLT3, HTR2A, HTR2B, INSR, MAP2K1, MAP3K7, MIF, PTPN1, SRC |
3.99808 |
|
[BP] GO:0021885 |
forebrain cell migration
|
AXL, DRD1, DRD2, EGFR, HTR6 |
3.96192 |
|
[BP] GO:0044057 |
None
|
ADORA1, ADORA3, ADRA1A, ADRA2A, CACNA1C, CHRM2, DRD2, DRD3, EGFR, GPR35, HTR2A, HTR2C, KCNH2, SMAD3 |
3.95283 |
|
[BP] GO:0007204 |
positive regulation of cytosolic calcium ion concentration
|
ADRA1A, CACNA1C, DRD1, DRD2, ESR1, F2, GPR35, HTR2A, HTR2B, HTR2C |
3.94829 |
|
[BP] GO:0001676 |
long-chain fatty acid metabolic process
|
CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, PTGES, TBXAS1 |
3.93029 |
|
[BP] GO:0071071 |
None
|
FABP3, HTR2A, HTR2B, HTR2C |
3.92959 |
|
[BP] GO:0070920 |
None
|
EGFR, ESR1, MAP2K1, TERT |
3.92959 |
|
[BP] GO:0032225 |
None
|
DRD1, DRD2, DRD3, SLC6A4 |
3.92959 |
|
[BP] GO:0060402 |
None
|
ADRA1A, CACNA1C, DRD2, HTR2A, HTR2B, HTR2C |
3.92736 |
|
[BP] GO:0034599 |
cellular response to oxidative stress
|
AKR1B1, APEX1, AXL, CYP1B1, EGFR, HSPA1A, MMP9, RELA, SRC |
3.92644 |
|
[BP] GO:0045931 |
positive regulation of mitotic cell cycle
|
APEX1, APP, CDC25B, CYP1A1, DRD3, DUSP3, INSR, TERT |
3.92573 |
|
[BP] GO:0071495 |
cellular response to endogenous stimulus
|
ADRA2A, AKR1B1, APEX1, APP, AR, DRD1, EGFR, ESR1, FLT3, IGF1R, INSR, MMP2, RELA, SLC6A4, SMAD3, SRC |
3.92428 |
|
[BP] GO:0010513 |
None
|
HTR2A, HTR2B, HTR2C |
3.92428 |
|
[BP] GO:1900274 |
regulation of phospholipase C activity
|
ADRA1A, EGFR, ESR1, HTR2A, HTR2B |
3.9161 |
|
[BP] GO:0010557 |
positive regulation of macromolecule biosynthetic process
|
APP, AR, AURKB, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, IGF1R, INSR, KDR, MAP2K1, MET, MMP12, PPARA, RELA, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A |
3.89145 |
|
[BP] GO:0010038 |
response to metal ion
|
APP, BCL2, CA2, CYP1A1, CYP1A2, DRD2, EGFR, FABP4, MMP9, PTGES, TERT |
3.83155 |
|
[BP] GO:0008217 |
None
|
ADORA1, ADRA1A, AR, CNR1, DRD2, DRD3, PPARA, SMAD3 |
3.82226 |
|
[BP] GO:0051223 |
None
|
ACHE, ADRA2A, APP, CACNA1C, CNR1, DRD2, DRD3, EGFR, F2, HMGCR, HTR2B, MIF, MMP12, MTNR1B, PTPN1, SMAD3, SRC |
3.82005 |
|
[BP] GO:0050727 |
regulation of inflammatory response
|
ADORA1, CNR1, CNR2, CYP19A1, EGFR, ESR1, F2, FABP4, PPARA, RELA, SMAD3, TEK |
3.81441 |
|
[BP] GO:0051171 |
regulation of nitrogen compound metabolic process
|
ADORA1, ADORA3, ADRA1A, ADRA2A, APEX1, APP, AR, AURKB, BCL2, CA9, CDC25B, CSNK2A1, CYP1B1, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FABP3, FABP4, FLT3, GLO1, HMGCR, HSPA1A, HTR1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MAP2K1, MAP3K7, MET, MIF, MMP12, MMP9, MTNR1A, NUAK1, PIM1, POLA1, PPARA, PTPN1, RELA, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
3.7911 |
|
[BP] GO:0051094 |
positive regulation of developmental process
|
APP, AR, AXL, BCL2, CA2, CNR1, CYP1B1, DRD2, ESRRB, F3, HMGCR, HTR2A, HTR2C, INSR, KDR, MAP2K1, PIM1, RELA, SMAD3, SRC, TEK, TERT |
3.78028 |
|
[BP] GO:0008285 |
negative regulation of cell proliferation
|
ADORA1, ADORA3, ADRA1A, APP, AR, BCL2, CYP1B1, DRD2, FABP3, HSPA1A, MAP2K1, PTGES, SLC6A4, SMAD3, TERT, XDH |
3.7746 |
|
[BP] GO:0051897 |
positive regulation of protein kinase B signaling
|
AXL, EGFR, F10, F3, INSR, MET, SRC, TEK |
3.76513 |
|
[BP] GO:0042180 |
None
|
AKR1B1, AKR1B10, CYP19A1, GLO1, HMGCR, HSD17B3 |
3.75289 |
|
[BP] GO:0009895 |
negative regulation of catabolic process
|
ADORA1, ADRA2A, BCL2, CNR1, EGFR, HTR2B, MET, PPARA, RELA, SMAD3 |
3.74817 |
|
[BP] GO:0042542 |
response to hydrogen peroxide
|
AKR1B1, APEX1, AXL, BCL2, CYP1B1, RELA, SRC |
3.73266 |
|
[BP] GO:0042391 |
None
|
ADORA1, ADRA1A, APP, BCL2, CACNA1C, CNR1, CNR2, DRD1, GPR35, KCNH2, KDR, SRC |
3.68836 |
|
[BP] GO:0048608 |
reproductive structure development
|
AR, AXL, BCL2, CYP19A1, ESR1, HSD17B2, HSD17B3, INSR, MAP2K1, SRC |
3.65075 |
|
[BP] GO:2001234 |
negative regulation of apoptotic signaling pathway
|
AR, BCL2, HSPA1A, MIF, MMP9, PTPN1, RELA, SRC, TERT |
3.65075 |
|
[BP] GO:0051701 |
interaction with host
|
AXL, EGFR, HSPA1A, HTR2A, INSR, MET, SMAD3, SRC |
3.64856 |
|
[BP] GO:0051282 |
None
|
CACNA1C, DRD1, DRD2, F2, HTR2A, HTR2B, HTR2C |
3.60761 |
|
[BP] GO:0045776 |
None
|
ADORA1, CNR1, DRD2, DRD3, PPARA |
3.59725 |
|
[BP] GO:0032872 |
regulation of stress-activated MAPK cascade
|
APP, DUSP3, EGFR, HMGCR, IGF1R, MAP2K1, MAP3K7, PTPN1, XDH |
3.58912 |
|
[BP] GO:0070302 |
regulation of stress-activated protein kinase signaling cascade
|
APP, DUSP3, EGFR, HMGCR, IGF1R, MAP2K1, MAP3K7, PTPN1, XDH |
3.57393 |
|
[BP] GO:0050728 |
negative regulation of inflammatory response
|
ADORA1, CNR2, CYP19A1, F2, PPARA, SMAD3, TEK |
3.5618 |
|
[BP] GO:0051098 |
regulation of binding
|
APP, AURKB, BCL2, CYP2D6, MET, MMP9, PPARA, SMAD3, SRC, TERT, TNKS |
3.55439 |
|
[BP] GO:0006584 |
None
|
AKR1B1, DRD1, DRD2, DRD3, MAOA |
3.55285 |
|
[BP] GO:0009712 |
None
|
AKR1B1, DRD1, DRD2, DRD3, MAOA |
3.55285 |
|
[BP] GO:0048148 |
None
|
DRD1, DRD2, DRD3, HTR2A |
3.55226 |
|
[BP] GO:0048870 |
cell motility
|
AXL, CNR2, CYP1B1, DRD1, DRD2, EGFR, F2, FUT7, HTR2B, HTR6, KDR, MAP2K1, MIF, MMP1, MMP12, MMP9, SRC, TEK |
3.53479 |
|
[BP] GO:0048661 |
positive regulation of smooth muscle cell proliferation
|
AKR1B1, EGFR, HMGCR, MMP2, MMP9, TERT |
3.5305 |
|
[BP] GO:0060401 |
None
|
ADRA1A, CACNA1C, DRD2, HTR2A, HTR2B, HTR2C |
3.5305 |
|
[BP] GO:0040008 |
regulation of growth
|
APP, AR, BCL2, CSNK2A1, DRD2, DRD3, EGFR, ESR2, F2, HSPA1A, INSR, PIM1, SLC6A4, SMAD3, TNKS2 |
3.52499 |
|
[BP] GO:0050999 |
None
|
CNR1, CNR2, EGFR, HTR2B, TERT |
3.51199 |
|
[BP] GO:0035690 |
cellular response to drug
|
AKR1B1, APEX1, AXL, CYP1B1, DRD1, EGFR, KCNH2, KDR, RELA, SRC |
3.50617 |
|
[BP] GO:0009755 |
hormone-mediated signaling pathway
|
AR, ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC, SRC |
3.49292 |
|
[BP] GO:0051051 |
negative regulation of transport
|
ADORA1, ADRA2A, APP, BCL2, CNR1, DRD2, DRD3, GPR35, HMGCR, HSPA1A, HTR2A, KCNH2, MMP9 |
3.49292 |
|
[BP] GO:0016477 |
cell migration
|
AXL, CNR2, CYP1B1, DRD1, DRD2, EGFR, F2, FUT7, HTR2B, HTR6, KDR, MIF, MMP1, MMP12, MMP9, SRC, TEK |
3.48012 |
|
[BP] GO:0060255 |
regulation of macromolecule metabolic process
|
ACHE, ADORA1, ADORA3, ADRA1A, ADRA2A, APEX1, APP, AR, AURKB, BCL2, CA9, CDC25B, CSNK2A1, CYP1A2, CYP1B1, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FABP4, FLT3, GLO1, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MAP2K1, MAP3K7, MET, MIF, MMP12, MMP9, NUAK1, PIM1, POLA1, PPARA, PTPN1, RELA, RORC, SLC6A4, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
3.47881 |
|
[BP] GO:0019373 |
epoxygenase P450 pathway
|
CYP1A1, CYP1A2, CYP1B1, CYP2C19 |
3.47658 |
|
[BP] GO:0040011 |
locomotion
|
AXL, CNR2, CYP1B1, DRD1, DRD2, EGFR, F2, FUT7, HTR2B, HTR6, KDR, MAP2K1, MET, MIF, MMP1, MMP12, MMP9, SRC, TEK |
3.47502 |
|
[BP] GO:0009416 |
response to light stimulus
|
APP, AURKB, BCL2, DRD1, DRD2, DRD3, EGFR, HMGCR, RELA, TYR |
3.475 |
|
[BP] GO:1903522 |
None
|
ADORA1, ADORA3, ADRA1A, ADRA2A, CACNA1C, CHRM2, DRD2, EGFR, HTR2A, KCNH2 |
3.475 |
|
[BP] GO:1904062 |
None
|
ADRA2A, APP, CACNA1C, DRD1, DRD2, DRD3, F2, GPR35, KCNH2, MMP9 |
3.44944 |
|
[BP] GO:0051246 |
regulation of protein metabolic process
|
ADORA1, ADRA1A, ADRA2A, APP, AR, BCL2, CDC25B, CSNK2A1, DRD1, DRD2, DUSP3, EGFR, ESR1, F2, F3, FABP4, FLT3, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MAP2K1, MAP3K7, MIF, MMP9, NUAK1, PTPN1, RELA, SMAD3, SRC, TEK, XDH |
3.44736 |
|
[BP] GO:0009820 |
alkaloid metabolic process
|
CYP1A2, CYP2D6, CYP3A4 |
3.44192 |
|
[BP] GO:0010511 |
None
|
HTR2A, HTR2B, HTR2C |
3.44192 |
|
[BP] GO:0010959 |
None
|
ADORA1, ADRA2A, BCL2, CACNA1C, DRD1, DRD2, DRD3, F2, GPR35, HTR2A, KCNH2 |
3.44192 |
|
[BP] GO:0007268 |
None
|
CHRM2, DRD1, DRD2, DRD3, HTR2A, HTR2C, HTR6, HTR7, MTNR1B, SLC6A2 |
3.39156 |
|
[BP] GO:0098916 |
None
|
CHRM2, DRD1, DRD2, DRD3, HTR2A, HTR2C, HTR6, HTR7, MTNR1B, SLC6A2 |
3.39156 |
|
[BP] GO:0050433 |
None
|
ADRA2A, CNR1, DRD2, DRD3, HTR2A |
3.38983 |
|
[BP] GO:0038083 |
peptidyl-tyrosine autophosphorylation
|
EGFR, IGF1R, INSR, KDR, SRC |
3.38983 |
|
[BP] GO:0050730 |
None
|
ADORA1, ADRA2A, APP, EGFR, FLT3, HTR2A, MIF, PTPN1, SRC |
3.37507 |
|
[BP] GO:0050794 |
regulation of cellular process
|
ACHE, ADORA1, ADORA3, ADRA1A, ADRA2A, AKR1B1, APEX1, APP, AR, AURKB, AXL, BCL2, CA1, CA2, CA7, CA9, CACNA1C, CDC25B, CHRM2, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1B1, CYP2D6, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F2, F3, FABP3, FABP4, FLT3, GLO1, GPR35, HMGCR, HSPA1A, HTR1A, HTR2A, HTR2B, HTR2C, HTR5A, HTR6, HTR7, IGF1R, INSR, KCNH2, KDR, MAP2K1, MAP3K7, MET, MIF, MMP1, MMP12, MMP2, MMP9, MTNR1A, MTNR1B, NUAK1, PIM1, POLA1, POLB, PPARA, PTGES, PTPN1, RELA, RORC, SIGMAR1, SLC6A4, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
3.36151 |
|
[BP] GO:0008542 |
None
|
APP, DRD1, DRD2, DRD3, HMGCR |
3.3474 |
|
[BP] GO:1904063 |
None
|
ADRA2A, DRD2, DRD3, GPR35, KCNH2, MMP9 |
3.33617 |
|
[BP] GO:1900542 |
None
|
ADRA2A, DRD1, DRD2, DRD3, ESRRB, HTR2A, INSR, MTNR1A, PPARA |
3.3344 |
|
[BP] GO:0051953 |
None
|
ADORA1, ADRA2A, CNR1, DRD2 |
3.33182 |
|
[BP] GO:0034762 |
None
|
ADRA2A, APP, BCL2, CA2, CACNA1C, DRD1, DRD2, DRD3, F2, GPR35, KCNH2, MMP9 |
3.33056 |
|
[BP] GO:0003006 |
developmental process involved in reproduction
|
ALPL, AR, AXL, BCL2, CDC25B, CYP19A1, EGFR, ESR1, ESRRB, HSD17B2, HSD17B3, INSR, MAP2K1, SRC |
3.31527 |
|
[BP] GO:0010518 |
positive regulation of phospholipase activity
|
ADRA1A, EGFR, ESR1, HTR2A, HTR2B |
3.31036 |
|
[BP] GO:0090066 |
None
|
ADORA1, ADRA1A, ADRA2A, DRD1, EGFR, HMGCR, HTR1A, HTR2A, HTR2B, HTR7, SLC6A4 |
3.30026 |
|
[BP] GO:0008210 |
estrogen metabolic process
|
CYP19A1, CYP1B1, HSD17B1, HSD17B2 |
3.26223 |
|
[BP] GO:0007202 |
None
|
ADRA1A, EGFR, HTR2A, HTR2B |
3.26223 |
|
[BP] GO:0051940 |
None
|
DRD1, DRD2, DRD3 |
3.26182 |
|
[BP] GO:0051584 |
None
|
DRD1, DRD2, DRD3 |
3.26182 |
|
[BP] GO:0006140 |
None
|
ADRA2A, DRD1, DRD2, DRD3, ESRRB, HTR2A, INSR, MTNR1A, PPARA |
3.24477 |
|
[BP] GO:0060341 |
regulation of cellular localization
|
ADRA2A, APP, AR, BCL2, CACNA1C, CSNK2A1, DRD1, DRD2, DRD3, EGFR, F2, HMGCR, MAP2K1, PTPN1, SMAD3, SRC, TERT |
3.2019 |
|
[BP] GO:2001023 |
None
|
CNR1, DRD1, DRD2, DRD3, HTR2A, MET |
3.18044 |
|
[BP] GO:0051047 |
None
|
ACHE, ADORA1, CYP19A1, DRD2, DRD3, EGFR, HTR2B, MIF, MMP12, SLC6A4, SRC |
3.17247 |
|
[BP] GO:0098900 |
None
|
ADRA1A, CACNA1C, CNR1, CNR2, GPR35 |
3.15689 |
|
[BP] GO:0007632 |
None
|
APP, DRD1, DRD2, DRD3, HMGCR |
3.15689 |
|
[BP] GO:0051588 |
None
|
DRD1, DRD2, DRD3, HTR1A, HTR2C, SLC6A4 |
3.15672 |
|
[BP] GO:0009605 |
response to external stimulus
|
ADORA1, ADRA1A, ALPL, AXL, BCL2, CHRM2, CNR1, CNR2, CYP1A1, CYP1A2, DRD3, EGFR, F2, HMGCR, HTR2A, MMP12, PTGES, RELA, SLC6A4, SMAD3, SRC, TYR |
3.14452 |
|
[BP] GO:0001975 |
None
|
CNR2, DRD1, DRD2, DRD3 |
3.1338 |
|
[BP] GO:0019933 |
None
|
ADRA1A, ADRA2A, DRD1, DRD2, DRD3, HTR5A |
3.13226 |
|
[BP] GO:0033555 |
multicellular organismal response to stress
|
BCL2, DRD1, HTR1A, HTR2C, SLC6A2 |
3.12191 |
|
[BP] GO:0007584 |
response to nutrient
|
ALPL, CNR1, CYP1A1, EGFR, HMGCR, RELA, SLC6A4, TYR |
3.08814 |
|
[BP] GO:0010564 |
regulation of cell cycle process
|
APEX1, APP, AURKB, BCL2, CDC25B, CSNK2A1, CYP1A1, DRD2, DRD3, EGFR, HSPA1A, INSR, MIF, TERT, TNKS |
3.08814 |
|
[BP] GO:0032768 |
None
|
CNR1, CNR2, EGFR, HTR2B, TERT |
3.08768 |
|
[BP] GO:0001101 |
response to acid chemical
|
AKR1B1, EGFR, FABP3, HSD17B2, KDR, MMP2, PTGES, RELA, SLC6A4, SRC |
3.0635 |
|
[BP] GO:0034766 |
None
|
ADRA2A, DRD2, DRD3, GPR35, KCNH2, MMP9 |
3.05969 |
|
[BP] GO:0071417 |
cellular response to organonitrogen compound
|
AKR1B1, APEX1, APP, DRD1, EGFR, IGF1R, INSR, MMP2, RELA, SLC6A4, SRC |
3.05409 |
|
[BP] GO:0001819 |
positive regulation of cytokine production
|
ADRA2A, CYP1B1, DRD2, HSPA1A, HTR2B, MAP3K7, MIF, MMP12, RELA, SMAD3, SRC |
3.05409 |
|
[BP] GO:0008610 |
lipid biosynthetic process
|
ACHE, AKR1B1, CES1, CSNK2A1, CYP19A1, CYP1A1, CYP3A4, HMGCR, HSD17B1, HSD17B2, HSD17B3, MIF, PTGES |
3.05079 |
|
[BP] GO:2001243 |
negative regulation of intrinsic apoptotic signaling pathway
|
BCL2, HSPA1A, MIF, MMP9, PTPN1, SRC |
3.03847 |
|
[BP] GO:0009653 |
anatomical structure morphogenesis
|
APP, AR, AXL, BCL2, CA2, CA9, CACNA1C, CYP1B1, DRD2, EGFR, ESR1, HTR2B, INSR, MET, MMP2, POLB, RELA, SLC6A4, SMAD3, SRC, TEK |
3.02851 |
|
[BP] GO:0042417 |
None
|
DRD1, DRD2, DRD3, MAOA |
3.0195 |
|
[BP] GO:0008209 |
androgen metabolic process
|
CYP19A1, CYP3A4, ESR1, HSD17B3 |
3.0195 |
|
[BP] GO:0014059 |
None
|
CNR1, DRD2, DRD3, HTR2A |
3.0195 |
|
[BP] GO:0009410 |
None
|
CNR1, CNR2, DRD1, DRD2, DRD3, EGFR, RELA |
2.97034 |
|
[BP] GO:0080135 |
regulation of cellular response to stress
|
APP, DUSP3, EGFR, HMGCR, HSPA1A, IGF1R, MAP2K1, MAP3K7, MET, MIF, NUAK1, PTPN1, TERT, XDH |
2.97034 |
|
[BP] GO:0043266 |
None
|
ADORA1, ADRA2A, DRD1, DRD2, HTR2A, KCNH2 |
2.97034 |
|
[BP] GO:0042752 |
None
|
ADORA1, DRD2, DRD3, PPARA, RORC, TOP2A |
2.97034 |
|
[BP] GO:0090276 |
None
|
ADRA2A, CACNA1C, CNR1, DRD2, EGFR, HMGCR, HTR2C, MTNR1B |
2.96422 |
|
[BP] GO:0034502 |
protein localization to chromosome
|
AURKB, ESR1, TERT, TNKS, TNKS2 |
2.9586 |
|
[BP] GO:0010517 |
regulation of phospholipase activity
|
ADRA1A, EGFR, ESR1, HTR2A, HTR2B |
2.9586 |
|
[BP] GO:0070988 |
demethylation
|
APEX1, CYP1A1, CYP1A2, CYP2D6, CYP3A4 |
2.9586 |
|
[BP] GO:0051234 |
None
|
ABCG2, ACHE, ADORA1, ADRA1A, ADRA2A, ALOX5, APP, AR, AXL, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CACNA1C, DRD1, DRD2, DRD3, EGFR, F10, F2, FABP3, HSPA1A, HTR2A, HTR2B, HTR2C, KCNH2, MIF, MMP12, MMP9, PPARA, SIGMAR1, SLC6A2, SLC6A4, SRC, TERT, TNKS, XDH |
2.95746 |
|
[BP] GO:0051172 |
None
|
ADRA2A, APEX1, APP, AR, AURKB, CSNK2A1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, F2, FABP4, HMGCR, HSPA1A, IGF1R, MIF, MMP12, MMP9, PPARA, PTPN1, RELA, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, XDH |
2.94328 |
|
[BP] GO:0019935 |
None
|
ADRA1A, ADRA2A, DRD1, DRD2, DRD3, HTR5A |
2.92919 |
|
[BP] GO:0034763 |
None
|
ADRA2A, DRD2, DRD3, GPR35, KCNH2, MMP9 |
2.92919 |
|
[BP] GO:0043393 |
regulation of protein binding
|
APP, AURKB, BCL2, MET, MMP9, PPARA, SRC, TERT |
2.92708 |
|
[BP] GO:0002209 |
None
|
BCL2, DRD1, HTR1A, HTR2C |
2.91346 |
|
[BP] GO:0001662 |
None
|
BCL2, DRD1, HTR1A, HTR2C |
2.91346 |
|
[BP] GO:0051828 |
entry into other organism involved in symbiotic interaction
|
AXL, EGFR, HSPA1A, HTR2A, MET, SRC |
2.91135 |
|
[BP] GO:0030260 |
entry into host cell
|
AXL, EGFR, HSPA1A, HTR2A, MET, SRC |
2.91135 |
|
[BP] GO:0051806 |
entry into cell of other organism involved in symbiotic interaction
|
AXL, EGFR, HSPA1A, HTR2A, MET, SRC |
2.91135 |
|
[BP] GO:0044409 |
entry into host
|
AXL, EGFR, HSPA1A, HTR2A, MET, SRC |
2.91135 |
|
[BP] GO:0070301 |
cellular response to hydrogen peroxide
|
AKR1B1, APEX1, AXL, CYP1B1, RELA |
2.89924 |
|
[BP] GO:0051179 |
None
|
ABCG2, ACHE, ADORA1, ADRA1A, ADRA2A, ALOX5, APP, AR, AURKB, AXL, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CACNA1C, DRD1, DRD2, DRD3, EGFR, ESR1, F10, F2, FABP3, HSPA1A, HTR2A, HTR2B, HTR2C, KCNH2, MIF, MMP12, MMP9, PPARA, SIGMAR1, SLC6A2, SLC6A4, SRC, TERT, TNKS, TNKS2, XDH |
2.88355 |
|
[BP] GO:0060193 |
positive regulation of lipase activity
|
ADRA1A, EGFR, ESR1, HTR2A, HTR2B |
2.86681 |
|
[BP] GO:2001237 |
negative regulation of extrinsic apoptotic signaling pathway
|
AR, BCL2, HSPA1A, RELA, SRC, TERT |
2.86681 |
|
[BP] GO:0001659 |
None
|
ADORA1, DRD1, DRD2, HTR2A |
2.86493 |
|
[BP] GO:0045744 |
None
|
ADRA2A, DRD2, DRD3, MET |
2.86493 |
|
[BP] GO:0007166 |
cell surface receptor signaling pathway
|
ADORA1, ADORA3, APP, AXL, BCL2, CA1, CSNK2A1, DRD2, EGFR, F2, F3, FLT3, GPR35, IGF1R, INSR, KDR, MAP3K7, MET, MIF, MMP2, MMP9, PTPN1, RELA, SMAD3, SRC, TEK, TNKS, TNKS2 |
2.86435 |
|
[BP] GO:0090068 |
positive regulation of cell cycle process
|
APEX1, APP, AURKB, CDC25B, CYP1A1, DRD2, DRD3, INSR, TERT |
2.86163 |
|
[BP] GO:0002031 |
None
|
DRD2, DRD3, HTR2B |
2.85921 |
|
[BP] GO:0060736 |
prostate gland growth
|
AR, CYP19A1, ESR1 |
2.85921 |
|
[BP] GO:0007169 |
transmembrane receptor protein tyrosine kinase signaling pathway
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, MMP2, MMP9, PTPN1, SRC, TEK |
2.85137 |
|
[BP] GO:0009314 |
response to radiation
|
APP, AURKB, BCL2, DRD1, DRD2, DRD3, EGFR, HMGCR, POLB, RELA, TYR |
2.83023 |
|
[BP] GO:0032496 |
response to lipopolysaccharide
|
ALPL, AXL, CNR1, CNR2, CYP1A1, CYP1A2, PTGES, RELA, SRC |
2.83023 |
|
[BP] GO:0007613 |
None
|
CNR1, DRD1, DRD2, HTR2A, INSR, SLC6A4 |
2.82979 |
|
[BP] GO:2000026 |
regulation of multicellular organismal development
|
APP, AR, AXL, BCL2, CA2, CNR1, CYP1B1, DRD2, DRD3, EGFR, ESR1, ESRRA, F2, F3, HMGCR, INSR, KDR, MAP2K1, PIM1, RELA, SLC6A4, SMAD3, SRC, TEK, TERT, XDH |
2.82915 |
|
[BP] GO:0007167 |
enzyme linked receptor protein signaling pathway
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MAP3K7, MET, MMP2, MMP9, PTPN1, SMAD3, SRC, TEK |
2.82915 |
|
[BP] GO:0019752 |
carboxylic acid metabolic process
|
ALOX5, CES1, CES2, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, FABP3, GLO1, MIF, PIM1, PPARA, PTGES, TBXAS1, TYR |
2.82915 |
|
[BP] GO:0051254 |
None
|
APP, AR, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, HSPA1A, INSR, MAP2K1, MET, MMP12, PPARA, RELA, RORC, SMAD3, SRC, TERT, TNKS, TOP2A |
2.82915 |
|
[BP] GO:0007208 |
None
|
HTR2A, HTR2C |
2.82915 |
|
[BP] GO:0009115 |
None
|
AOX1, XDH |
2.82915 |
|
[BP] GO:0006286 |
base-excision repair, base-free sugar-phosphate removal
|
APEX1, POLB |
2.82915 |
|
[BP] GO:0022029 |
None
|
DRD1, DRD2, EGFR, HTR6 |
2.82915 |
|
[BP] GO:0043278 |
None
|
CNR1, DRD2, DRD3, RELA |
2.82915 |
|
[BP] GO:0014072 |
None
|
CNR1, DRD2, DRD3, RELA |
2.82915 |
|
[BP] GO:0042596 |
None
|
BCL2, DRD1, HTR1A, HTR2C |
2.82915 |
|
[BP] GO:1901652 |
response to peptide
|
AKR1B1, APEX1, APP, FABP3, IGF1R, INSR, PPARA, RELA, SRC, TEK |
2.82256 |
|
[BP] GO:0032103 |
positive regulation of response to external stimulus
|
CNR1, EGFR, F2, F3, FABP4, KDR, MET, MIF, SMAD3 |
2.82043 |
|
[BP] GO:0048869 |
cellular developmental process
|
ACHE, ALPL, APP, AR, AXL, BCL2, CDC25B, CES1, CYP1A1, DRD1, DRD2, EGFR, ESR1, ESRRB, FABP4, FLT3, FUT7, GLO1, HMGCR, HTR2B, KDR, MAP2K1, MET, MIF, MMP2, MMP9, RORC, SMAD3, SRC, TEK, TERT, TOP2A |
2.79273 |
|
[BP] GO:1901699 |
cellular response to nitrogen compound
|
AKR1B1, APEX1, APP, DRD1, EGFR, IGF1R, INSR, MMP2, RELA, SLC6A4, SRC |
2.79171 |
|
[BP] GO:0002009 |
morphogenesis of an epithelium
|
AR, BCL2, CA2, CA9, EGFR, ESR1, MET, SMAD3, SRC |
2.7869 |
|
[BP] GO:0006082 |
organic acid metabolic process
|
ABCG2, ALOX5, CES1, CES2, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, FABP3, GLO1, MIF, PIM1, PPARA, PTGES, TBXAS1, TYR |
2.78435 |
|
[BP] GO:0090218 |
positive regulation of lipid kinase activity
|
F2, FLT3, SRC, TEK |
2.78299 |
|
[BP] GO:1902893 |
None
|
PPARA, RELA, SMAD3, TERT |
2.78299 |
|
[BP] GO:0010907 |
None
|
ESRRB, INSR, PPARA, SRC |
2.78299 |
|
[BP] GO:0051704 |
multi-organism process
|
APP, AXL, BCL2, CHRM2, CYP1A1, DRD3, EGFR, F2, HSPA1A, HTR2A, INSR, KDR, MAP2K1, MET, MMP1, MMP12, POLA1, RELA, SLC6A4, SMAD3, SRC |
2.77906 |
|
[BP] GO:0006367 |
transcription initiation from RNA polymerase II promoter
|
AR, ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC |
2.76767 |
|
[BP] GO:0048545 |
response to steroid hormone
|
ALPL, AR, BCL2, CA2, EGFR, FLT3, RELA, SRC |
2.76767 |
|
[BP] GO:0015872 |
None
|
DRD1, SLC6A2, SLC6A4 |
2.76767 |
|
[BP] GO:0042738 |
exogenous drug catabolic process
|
CYP1A2, CYP2C19, CYP3A4 |
2.76767 |
|
[BP] GO:0045759 |
None
|
CNR1, CNR2, GPR35 |
2.76767 |
|
[BP] GO:0070989 |
oxidative demethylation
|
CYP1A2, CYP2D6, CYP3A4 |
2.76767 |
|
[BP] GO:0009991 |
response to extracellular stimulus
|
ALPL, AXL, BCL2, CNR1, CYP1A1, EGFR, HMGCR, RELA, SLC6A4, SRC, TYR |
2.76738 |
|
[BP] GO:0040014 |
regulation of multicellular organism growth
|
APP, BCL2, DRD2, DRD3, TNKS2 |
2.74253 |
|
[BP] GO:1901617 |
organic hydroxy compound biosynthetic process
|
AKR1B1, CES1, CYP19A1, CYP3A4, HMGCR, HSD17B3, TYR |
2.74032 |
|
[BP] GO:0009889 |
regulation of biosynthetic process
|
ADORA3, ADRA2A, APEX1, APP, AR, AURKB, BCL2, CA9, CSNK2A1, CYP1B1, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, FABP3, FABP4, GLO1, HMGCR, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MAP2K1, MAP3K7, MET, MMP12, MTNR1A, PIM1, POLA1, PPARA, RELA, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A |
2.73612 |
|
[BP] GO:0045913 |
None
|
ESRRB, HTR2A, INSR, PPARA, SRC |
2.71393 |
|
[BP] GO:0045893 |
None
|
APP, AR, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, INSR, MAP2K1, MET, MMP12, PPARA, RELA, RORC, SMAD3, SRC, TERT, TNKS, TOP2A |
2.67479 |
|
[BP] GO:1903508 |
None
|
APP, AR, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, INSR, MAP2K1, MET, MMP12, PPARA, RELA, RORC, SMAD3, SRC, TERT, TNKS, TOP2A |
2.67479 |
|
[BP] GO:1902680 |
None
|
APP, AR, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, INSR, MAP2K1, MET, MMP12, PPARA, RELA, RORC, SMAD3, SRC, TERT, TNKS, TOP2A |
2.6712 |
|
[BP] GO:0009056 |
catabolic process
|
ACHE, ADORA1, AKR1B10, AOX1, AURKB, CES2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, CYP3A4, FABP3, FABP4, FUT7, HSPA1A, MAOA, MMP1, MMP12, MMP2, MMP9, SRC, XDH |
2.67005 |
|
[BP] GO:0006703 |
estrogen biosynthetic process
|
CYP19A1, HSD17B1, HSD17B2 |
2.67005 |
|
[BP] GO:0060134 |
None
|
DRD1, DRD2, DRD3 |
2.67005 |
|
[BP] GO:0032230 |
positive regulation of synaptic transmission, GABAergic
|
ADRA1A, CA2, CA7 |
2.67005 |
|
[BP] GO:0033604 |
None
|
ADRA2A, CNR1, DRD2 |
2.67005 |
|
[BP] GO:0042737 |
drug catabolic process
|
ACHE, CYP1A2, CYP2C19, CYP2D6, CYP3A4, MAOA |
2.67005 |
|
[BP] GO:0001503 |
ossification
|
ALPL, BCL2, EGFR, MMP2, MMP9, TEK |
2.67005 |
|
[BP] GO:0048534 |
hematopoietic or lymphoid organ development
|
BCL2, FLT3, KDR, MAP2K1, POLB, TEK, TYR |
2.66917 |
|
[BP] GO:0002682 |
regulation of immune system process
|
ADORA1, APP, AXL, BCL2, CA2, CNR1, CNR2, CYP19A1, DRD2, DUSP3, ESR1, ESRRA, F2, HSPA1A, MAP3K7, MIF, MMP12, MMP2, PTPN1, RELA, SMAD3, SRC |
2.66213 |
|
[BP] GO:0002237 |
response to molecule of bacterial origin
|
ALPL, AXL, CNR1, CNR2, CYP1A1, CYP1A2, PTGES, RELA, SRC |
2.65156 |
|
[BP] GO:0010638 |
positive regulation of organelle organization
|
AURKB, BCL2, DRD3, HSPA1A, INSR, KDR, MET, MMP9, SMAD3, SRC, TEK, TNKS, TNKS2 |
2.65156 |
|
[BP] GO:2000377 |
regulation of reactive oxygen species metabolic process
|
BCL2, CYP1B1, EGFR, F2, INSR, SMAD3, XDH |
2.63974 |
|
[BP] GO:0008306 |
None
|
APP, DRD1, DRD2, DRD3, HMGCR |
2.63854 |
|
[BP] GO:0006810 |
None
|
ABCG2, ACHE, ADORA1, ADRA1A, ADRA2A, ALOX5, APP, AR, AXL, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CACNA1C, DRD1, DRD2, DRD3, F10, F2, FABP3, HSPA1A, HTR2A, HTR2B, HTR2C, KCNH2, MIF, MMP12, MMP9, PPARA, SIGMAR1, SLC6A2, SLC6A4, SRC, TNKS, XDH |
2.6337 |
|
[BP] GO:0001817 |
regulation of cytokine production
|
ADRA2A, AXL, CYP1B1, DRD2, F2, HSPA1A, HTR2B, MAP3K7, MIF, MMP12, RELA, SMAD3, SRC |
2.63341 |
|
[BP] GO:0032467 |
None
|
AURKB, CDC25B, DRD2, DRD3 |
2.61258 |
|
[BP] GO:0007189 |
None
|
ADRA1A, ADRA2A, DRD1, DRD2, DRD3 |
2.61258 |
|
[BP] GO:0050789 |
regulation of biological process
|
ACHE, ADORA1, ADORA3, ADRA1A, ADRA2A, AKR1B1, APEX1, APP, AR, AURKB, AXL, BCL2, CA1, CA2, CA7, CA9, CACNA1C, CDC25B, CHRM2, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F2, F3, FABP3, FABP4, FLT3, GLO1, GPR35, HMGCR, HSPA1A, HTR1A, HTR2A, HTR2B, HTR2C, HTR5A, HTR6, HTR7, IGF1R, INSR, KCNH2, KDR, MAP2K1, MAP3K7, MET, MIF, MMP1, MMP12, MMP2, MMP9, MTNR1A, MTNR1B, NUAK1, PIM1, POLA1, POLB, PPARA, PTGES, PTPN1, RELA, RORC, SIGMAR1, SLC6A4, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, XDH |
2.60613 |
|
[BP] GO:0048871 |
multicellular organismal homeostasis
|
ADORA1, AKR1B1, DRD1, DRD2, HTR2A, MET |
2.59624 |
|
[BP] GO:0050731 |
positive regulation of peptidyl-tyrosine phosphorylation
|
ADORA1, ADRA2A, FLT3, HTR2A, MIF, PTPN1, SRC |
2.58212 |
|
[BP] GO:0060065 |
uterus development
|
CYP19A1, ESR1, SRC |
2.58045 |
|
[BP] GO:0051580 |
None
|
DRD1, DRD2, DRD3 |
2.58045 |
|
[BP] GO:0051967 |
None
|
ADORA1, DRD2, HTR2A |
2.58045 |
|
[BP] GO:0048806 |
genitalia development
|
AXL, CYP19A1, ESR1, HSD17B3 |
2.57366 |
|
[BP] GO:0014075 |
None
|
CNR2, DRD1, DRD2, DRD3 |
2.57366 |
|
[BP] GO:0097237 |
cellular response to toxic substance
|
AKR1B1, APEX1, AXL, CYP1B1, KDR, RELA |
2.56205 |
|
[BP] GO:0050679 |
None
|
AR, EGFR, F3, HTR2B, KDR, MMP12, TEK |
2.55716 |
|
[BP] GO:2001233 |
regulation of apoptotic signaling pathway
|
AR, BCL2, HSPA1A, MIF, MMP9, PTPN1, RELA, SMAD3, SRC, TERT |
2.54989 |
|
[BP] GO:0043270 |
None
|
ADORA1, ADRA2A, DRD1, DRD2, F2, KCNH2, MIF, SLC6A4 |
2.54823 |
|
[BP] GO:0032413 |
None
|
ADRA2A, DRD2, DRD3, GPR35, MMP9 |
2.53957 |
|
[BP] GO:1901654 |
None
|
AKR1B1, AR, CA9, CSNK2A1, EGFR, RELA, SRC |
2.51632 |
|
[BP] GO:0048609 |
multicellular organismal reproductive process
|
AKR1B1, APP, AR, AXL, CNR1, CYP1A1, DRD1, EGFR, ESR1, MTNR1A, SLC6A4, SRC |
2.5136 |
|
[BP] GO:0048638 |
regulation of developmental growth
|
APP, AR, BCL2, DRD2, DRD3, INSR, PIM1, SLC6A4, TNKS2 |
2.50858 |
|
[BP] GO:1903798 |
None
|
EGFR, ESR1, MAP2K1 |
2.5006 |
|
[BP] GO:0001963 |
None
|
DRD1, DRD2, DRD3 |
2.5006 |
|
[BP] GO:0051937 |
None
|
DRD1, SLC6A2, SLC6A4 |
2.5006 |
|
[BP] GO:0070198 |
None
|
TERT, TNKS, TNKS2 |
2.5006 |
|
[BP] GO:0032355 |
response to estradiol
|
CYP1A2, EGFR, ESR1, ESRRA, HTR5A, SLC6A4 |
2.49632 |
|
[BP] GO:0051090 |
regulation of DNA binding transcription factor activity
|
ADORA3, APP, AR, CYP1B1, ESR1, ESR2, HSPA1A, MAP3K7, PIM1, RELA |
2.49632 |
|
[BP] GO:0032147 |
activation of protein kinase activity
|
ADORA1, ADRA2A, DRD2, EGFR, INSR, MAP2K1, MAP3K7, PTPN1, SRC |
2.48308 |
|
[BP] GO:0035094 |
response to nicotine
|
BCL2, CNR1, DRD2, RELA |
2.45802 |
|
[BP] GO:0010605 |
negative regulation of macromolecule metabolic process
|
APEX1, APP, AR, AURKB, CSNK2A1, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, F2, FABP4, HMGCR, HSPA1A, IGF1R, KDR, MAP2K1, MIF, MMP12, MMP9, PPARA, PTPN1, RELA, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, XDH |
2.44187 |
|
[BP] GO:0048660 |
regulation of smooth muscle cell proliferation
|
AKR1B1, EGFR, HMGCR, MMP2, MMP9, TERT |
2.43 |
|
[BP] GO:0043268 |
None
|
ADORA1, ADRA2A, DRD1, KCNH2 |
2.43 |
|
[BP] GO:1901224 |
None
|
APP, EGFR, MAP3K7, RELA |
2.43 |
|
[BP] GO:0033590 |
None
|
EGFR, RELA |
2.43 |
|
[BP] GO:0098502 |
DNA dephosphorylation
|
APEX1, POLB |
2.43 |
|
[BP] GO:0009822 |
alkaloid catabolic process
|
CYP2D6, CYP3A4 |
2.43 |
|
[BP] GO:0046110 |
None
|
AOX1, XDH |
2.43 |
|
[BP] GO:0060160 |
None
|
DRD2, DRD3 |
2.43 |
|
[BP] GO:0032849 |
positive regulation of cellular pH reduction
|
CA2, CA7 |
2.43 |
|
[BP] GO:0033602 |
None
|
CNR1, DRD2 |
2.43 |
|
[BP] GO:0002520 |
None
|
CACNA1C, SMAD3 |
2.43 |
|
[BP] GO:0030540 |
female genitalia development
|
AXL, CYP19A1, ESR1 |
2.43 |
|
[BP] GO:1900182 |
positive regulation of protein localization to nucleus
|
APP, EGFR, F2, SMAD3, SRC, TERT |
2.40134 |
|
[BP] GO:0046683 |
response to organophosphorus
|
APEX1, APP, RELA, SLC6A4, TEK, TYR |
2.40134 |
|
[BP] GO:0043436 |
oxoacid metabolic process
|
ALOX5, CES1, CES2, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, FABP3, GLO1, MIF, PIM1, PPARA, PTGES, TBXAS1, TYR |
2.40047 |
|
[BP] GO:0033273 |
response to vitamin
|
ALPL, CYP1A1, EGFR, RELA, TYR |
2.38531 |
|
[BP] GO:0051128 |
regulation of cellular component organization
|
APP, AR, AURKB, AXL, BCL2, CNR1, CSNK2A1, DRD2, DRD3, EGFR, ESR1, ESR2, F2, HSPA1A, IGF1R, INSR, KDR, MAP2K1, MET, MMP1, MMP9, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
2.38531 |
|
[BP] GO:0002793 |
None
|
ACHE, ADORA1, DRD2, EGFR, HTR2B, MIF, MMP12, SRC |
2.3733 |
|
[BP] GO:0006928 |
movement of cell or subcellular component
|
ADRA2A, APP, AXL, CNR2, CYP1B1, DRD1, DRD2, EGFR, F2, FUT7, HTR2B, HTR6, KDR, MAP2K1, MIF, MMP1, MMP12, MMP9, SRC, TEK |
2.37271 |
|
[BP] GO:0010628 |
positive regulation of gene expression
|
APP, AR, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, HSPA1A, INSR, MAP2K1, MET, MMP12, PPARA, RELA, RORC, SLC6A4, SMAD3, SRC, TERT, TNKS, TOP2A |
2.37271 |
|
[BP] GO:0019538 |
protein metabolic process
|
ACHE, ALPL, APP, AR, AURKB, AXL, BCL2, CDC25B, CSNK2A1, DRD1, DUSP3, EGFR, ESR1, F10, F2, F3, FLT3, FUT7, HTR2B, IGF1R, INSR, KCNH2, KDR, MAP2K1, MAP3K7, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIM1, POLB, PPARA, PTPN1, RELA, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
2.36978 |
|
[BP] GO:0031667 |
response to nutrient levels
|
ALPL, BCL2, CNR1, CYP1A1, EGFR, HMGCR, RELA, SLC6A4, SRC, TYR |
2.36831 |
|
[BP] GO:0032410 |
None
|
ADRA2A, DRD2, DRD3, GPR35, MMP9 |
2.36494 |
|
[BP] GO:1904355 |
positive regulation of telomere capping
|
AURKB, TNKS, TNKS2 |
2.3587 |
|
[BP] GO:0050678 |
None
|
AR, EGFR, F3, HTR2B, KDR, MMP12, SMAD3, TEK, XDH |
2.34673 |
|
[BP] GO:0045595 |
regulation of cell differentiation
|
APP, AR, AXL, BCL2, CA2, CNR1, DRD2, DRD3, EGFR, ESRRA, ESRRB, F2, HTR2A, HTR2C, KDR, MAP2K1, PPARA, RELA, RORC, SLC6A4, SMAD3, TERT, XDH |
2.34542 |
|
[BP] GO:0051781 |
None
|
AURKB, CDC25B, DRD2, DRD3, HTR2B |
2.34542 |
|
[BP] GO:1901989 |
None
|
APEX1, APP, CDC25B, CYP1A1, TERT |
2.34542 |
|
[BP] GO:0051283 |
None
|
DRD2, HTR2A, HTR2B, HTR2C |
2.32968 |
|
[BP] GO:0051209 |
None
|
DRD2, HTR2A, HTR2B, HTR2C |
2.32968 |
|
[BP] GO:0097366 |
None
|
CNR2, DRD1, DRD2, DRD3 |
2.32968 |
|
[BP] GO:0060191 |
regulation of lipase activity
|
ADRA1A, EGFR, ESR1, HTR2A, HTR2B |
2.32398 |
|
[BP] GO:0006464 |
cellular protein modification process
|
ALPL, APP, AR, AURKB, AXL, BCL2, CDC25B, CSNK2A1, DRD1, DUSP3, EGFR, ESR1, F10, F2, FLT3, FUT7, HTR2B, IGF1R, INSR, KCNH2, KDR, MAP2K1, MAP3K7, MET, NUAK1, PIM1, POLB, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
2.32176 |
|
[BP] GO:0036211 |
protein modification process
|
ALPL, APP, AR, AURKB, AXL, BCL2, CDC25B, CSNK2A1, DRD1, DUSP3, EGFR, ESR1, F10, F2, FLT3, FUT7, HTR2B, IGF1R, INSR, KCNH2, KDR, MAP2K1, MAP3K7, MET, NUAK1, PIM1, POLB, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
2.32176 |
|
[BP] GO:0007612 |
None
|
APP, DRD1, DRD2, DRD3, HMGCR, INSR |
2.31127 |
|
[BP] GO:0042058 |
None
|
ADORA1, ADRA2A, APP, EGFR, MMP9 |
2.30356 |
|
[BP] GO:0045821 |
None
|
ESRRB, HTR2A, INSR |
2.29298 |
|
[BP] GO:0014821 |
None
|
DRD1, DRD2, HTR2B |
2.29298 |
|
[BP] GO:0040007 |
None
|
ADRA1A, APP, AR, BCL2, CYP19A1, ESR1, SMAD3, SRC, TNKS2 |
2.28976 |
|
[BP] GO:0003012 |
None
|
ADORA1, ADRA1A, DRD1, DRD2, HTR2A, HTR2B, HTR7, KCNH2 |
2.28788 |
|
[BP] GO:0030336 |
None
|
ADORA1, ADORA3, APEX1, BCL2, CYP19A1, CYP1B1, DRD2, MIF |
2.27805 |
|
[BP] GO:0033554 |
cellular response to stress
|
AKR1B1, APEX1, AXL, BCL2, CA2, CA9, CYP1B1, EGFR, HSPA1A, MAP2K1, MAP3K7, MIF, MMP9, NUAK1, POLA1, POLB, PTPN1, RELA, SRC, TERT, TOP2A |
2.27342 |
|
[BP] GO:0042133 |
neurotransmitter metabolic process
|
ACHE, CYP1B1, HTR1A, MAOA, SLC6A4 |
2.26425 |
|
[BP] GO:0060359 |
None
|
CNR1, DRD1, DRD2, DRD3, RELA |
2.26425 |
|
[BP] GO:0051341 |
None
|
CNR1, CNR2, EGFR, HTR2B, TERT |
2.26425 |
|
[BP] GO:0006807 |
nitrogen compound metabolic process
|
ABCG2, ACHE, AKR1B1, AKR1B10, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CDC25B, CSNK2A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, CYP3A4, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F2, F3, FLT3, FUT7, GLO1, HMGCR, HSPA1A, HTR1A, HTR2B, HTR2C, IGF1R, INSR, KCNH2, KDR, MAOA, MAP2K1, MAP3K7, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIM1, POLA1, POLB, PPARA, PTPN1, RELA, RORC, SMAD3, SRC, TEK, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
2.25631 |
|
[BP] GO:0030534 |
None
|
APP, DRD1, DRD2, DRD3, HTR2A, PPARA |
2.25309 |
|
[BP] GO:0031329 |
regulation of cellular catabolic process
|
ADRA2A, APEX1, BCL2, CNR1, ESRRB, HSPA1A, HTR2A, HTR2B, INSR, KDR, MAP3K7, MET, PPARA, PTPN1 |
2.2415 |
|
[BP] GO:0032870 |
cellular response to hormone stimulus
|
ADRA2A, APEX1, AR, EGFR, ESR1, FLT3, INSR, RELA, SRC |
2.24085 |
|
[BP] GO:0045187 |
None
|
ADORA1, DRD2, DRD3 |
2.23308 |
|
[BP] GO:0051900 |
regulation of mitochondrial depolarization
|
BCL2, KDR, SRC |
2.23308 |
|
[BP] GO:0007617 |
None
|
APP, DRD1, MTNR1A |
2.23308 |
|
[BP] GO:0051197 |
None
|
ESRRB, HTR2A, INSR |
2.23308 |
|
[BP] GO:0016042 |
lipid catabolic process
|
ADORA1, AKR1B10, CYP19A1, CYP1A2, CYP1B1, CYP3A4, FABP3, FABP4 |
2.23308 |
|
[BP] GO:2000379 |
positive regulation of reactive oxygen species metabolic process
|
EGFR, F2, INSR, SMAD3, XDH |
2.22647 |
|
[BP] GO:1903169 |
None
|
ADRA2A, CACNA1C, DRD1, DRD2, F2, GPR35 |
2.22647 |
|
[BP] GO:0034765 |
None
|
ADRA2A, APP, CACNA1C, DRD1, DRD2, DRD3, F2, GPR35, KCNH2, MMP9 |
2.2192 |
|
[BP] GO:0051302 |
None
|
AURKB, CDC25B, DRD2, DRD3, ESRRB, HTR2B |
2.21125 |
|
[BP] GO:0045934 |
None
|
ADRA2A, APEX1, AR, AURKB, DRD2, DRD3, ESR1, ESR2, ESRRA, FABP4, HSPA1A, MMP12, PPARA, RELA, RORC, SMAD3, SRC, TERT, TNKS, TNKS2 |
2.21008 |
|
[BP] GO:0006352 |
DNA-templated transcription, initiation
|
AR, ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC |
2.19884 |
|
[BP] GO:1904951 |
positive regulation of establishment of protein localization
|
ACHE, APP, BCL2, DRD2, EGFR, F2, HTR2B, MIF, MMP12, SMAD3, SRC |
2.192 |
|
[BP] GO:0008150 |
biological_process
|
ABCG2, ACHE, ADORA1, ADORA3, ADRA1A, ADRA2A, AKR1B1, AKR1B10, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CACNA1C, CDC25B, CES1, CES2, CHRM2, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, CYP3A4, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F2, F3, FABP3, FABP4, FLT3, FUT7, GLO1, GPR35, HMGCR, HSD17B1, HSD17B2, HSD17B3, HSPA1A, HTR1A, HTR2A, HTR2B, HTR2C, HTR5A, HTR6, HTR7, IGF1R, INSR, KCNH2, KDR, MAOA, MAP2K1, MAP3K7, MET, MIF, MMP1, MMP12, MMP2, MMP9, MTNR1A, MTNR1B, NUAK1, PIM1, POLA1, POLB, PPARA, PTGES, PTPN1, RELA, RORC, SIGMAR1, SLC6A2, SLC6A4, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
2.18585 |
|
[BP] GO:0070213 |
None
|
TNKS, TNKS2 |
2.17988 |
|
[BP] GO:0006145 |
None
|
AOX1, XDH |
2.17988 |
|
[BP] GO:0038171 |
None
|
CNR1, CNR2 |
2.17988 |
|
[BP] GO:0018894 |
dibenzo-p-dioxin metabolic process
|
CYP1A1, CYP1A2 |
2.17988 |
|
[BP] GO:0035813 |
None
|
ADORA1, DRD2, DRD3 |
2.17988 |
|
[BP] GO:0071880 |
None
|
ADRA1A, ADRA2A, DRD2 |
2.17988 |
|
[BP] GO:0014074 |
response to purine-containing compound
|
APEX1, APP, RELA, SLC6A4, TEK, TYR |
2.17517 |
|
[BP] GO:1901653 |
cellular response to peptide
|
AKR1B1, APEX1, APP, IGF1R, INSR, RELA, SRC |
2.17236 |
|
[BP] GO:0048729 |
tissue morphogenesis
|
AR, BCL2, CA2, CA9, EGFR, ESR1, MET, SMAD3, SRC |
2.15089 |
|
[BP] GO:2000146 |
None
|
ADORA1, ADORA3, APEX1, BCL2, CYP19A1, CYP1B1, DRD2, MIF |
2.14384 |
|
[BP] GO:1903532 |
None
|
ACHE, CYP19A1, DRD2, EGFR, HTR2B, MIF, MMP12, SLC6A4, SRC |
2.14384 |
|
[BP] GO:0071396 |
cellular response to lipid
|
AR, AXL, EGFR, ESR1, FLT3, RELA, RORC, SLC6A4, SRC |
2.14384 |
|
[BP] GO:0044283 |
None
|
AKR1B1, ALOX5, CES1, CYP19A1, CYP1A1, CYP3A4, HMGCR, HSD17B3, MIF, PTGES |
2.13183 |
|
[BP] GO:0043207 |
response to external biotic stimulus
|
ALPL, AXL, BCL2, CHRM2, CNR1, CNR2, CYP1A1, CYP1A2, F2, MMP12, PTGES, RELA, SMAD3, SRC |
2.1265 |
|
[BP] GO:0010676 |
None
|
ESRRB, INSR, PPARA, SRC |
2.12533 |
|
[BP] GO:0050994 |
None
|
ADORA1, ADRA2A, CNR1, PPARA |
2.12533 |
|
[BP] GO:0043550 |
regulation of lipid kinase activity
|
F2, FLT3, SRC, TEK |
2.12533 |
|
[BP] GO:0015844 |
None
|
DRD1, SLC6A2, SLC6A4 |
2.12341 |
|
[BP] GO:0042749 |
None
|
ADORA1, DRD2, DRD3 |
2.12341 |
|
[BP] GO:0051591 |
None
|
APEX1, APP, RELA, TEK, TYR |
2.1202 |
|
[BP] GO:0010906 |
None
|
ESRRB, INSR, PPARA, RORC, SRC |
2.1202 |
|
[BP] GO:0003014 |
None
|
ADORA1, ADRA1A, AKR1B1, BCL2, DRD2 |
2.1202 |
|
[BP] GO:0051054 |
positive regulation of DNA metabolic process
|
AURKB, EGFR, IGF1R, INSR, SRC, TNKS, TNKS2 |
2.11987 |
|
[BP] GO:0016311 |
None
|
ALPL, APEX1, BCL2, CA3, CDC25B, DUSP3, POLB, PTPN1 |
2.11155 |
|
[BP] GO:0006936 |
None
|
ADRA1A, DRD1, DRD2, HTR2A, HTR2B, HTR7, KCNH2 |
2.10877 |
|
[BP] GO:0014066 |
regulation of phosphatidylinositol 3-kinase signaling
|
EGFR, F2, FLT3, KDR, TEK |
2.1018 |
|
[BP] GO:0032210 |
regulation of telomere maintenance via telomerase
|
AURKB, SRC, TNKS, TNKS2 |
2.10038 |
|
[BP] GO:0044267 |
cellular protein metabolic process
|
ALPL, APP, AR, AURKB, AXL, BCL2, CDC25B, CSNK2A1, DRD1, DUSP3, EGFR, ESR1, F10, F2, FLT3, FUT7, HTR2B, IGF1R, INSR, KCNH2, KDR, MAP2K1, MAP3K7, MET, MMP1, MMP2, NUAK1, PIM1, POLB, PTPN1, SMAD3, SRC, TEK, TNKS, TNKS2, TOP2A |
2.09716 |
|
[BP] GO:0009896 |
positive regulation of catabolic process
|
ADRA2A, CSNK2A1, ESRRB, HSPA1A, HTR2A, INSR, KDR, MAP3K7, PPARA, PTPN1 |
2.09649 |
|
[BP] GO:0009887 |
animal organ morphogenesis
|
AR, BCL2, CA2, EGFR, HTR2B, INSR, POLB, RELA, SLC6A4, SMAD3 |
2.08936 |
|
[BP] GO:0051893 |
regulation of focal adhesion assembly
|
KDR, SMAD3, SRC, TEK |
2.07518 |
|
[BP] GO:0090109 |
regulation of cell-substrate junction assembly
|
KDR, SMAD3, SRC, TEK |
2.07518 |
|
[BP] GO:0022612 |
gland morphogenesis
|
BCL2, EGFR, POLB |
2.07518 |
|
[BP] GO:1902895 |
None
|
RELA, SMAD3, TERT |
2.07518 |
|
[BP] GO:1904707 |
positive regulation of vascular smooth muscle cell proliferation
|
MMP2, MMP9, TERT |
2.07518 |
|
[BP] GO:0051194 |
None
|
ESRRB, HTR2A, INSR |
2.07518 |
|
[BP] GO:0030520 |
intracellular estrogen receptor signaling pathway
|
ESR1, ESR2, SRC |
2.07518 |
|
[BP] GO:0050995 |
None
|
ADORA1, ADRA2A, CNR1 |
2.07518 |
|
[BP] GO:1901184 |
None
|
ADORA1, ADRA2A, APP, EGFR, MMP9 |
2.06952 |
|
[BP] GO:2001236 |
regulation of extrinsic apoptotic signaling pathway
|
AR, BCL2, HSPA1A, RELA, SRC, TERT |
2.05763 |
|
[BP] GO:0000904 |
cell morphogenesis involved in differentiation
|
AR, AXL, MET, SRC, TEK |
2.05049 |
|
[BP] GO:0031623 |
None
|
ACHE, DRD2, DRD3, HTR2B |
2.04891 |
|
[BP] GO:0032922 |
None
|
DRD2, DRD3, PPARA, RORC |
2.04891 |
|
[BP] GO:0031326 |
regulation of cellular biosynthetic process
|
ADORA3, ADRA2A, APEX1, APP, AR, AURKB, BCL2, CA9, CSNK2A1, CYP1B1, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, FABP3, FABP4, GLO1, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, MAP2K1, MAP3K7, MET, MMP12, MTNR1A, PIM1, POLA1, PPARA, RELA, RORC, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A |
2.04505 |
|
[BP] GO:0048589 |
None
|
ADRA1A, APP, AR, BCL2, CYP19A1, ESR1, SMAD3, TNKS2 |
2.04439 |
|
[BP] GO:0044062 |
None
|
ADORA1, DRD2, DRD3 |
2.02264 |
|
[BP] GO:0009404 |
toxin metabolic process
|
CYP1A1, CYP1A2, CYP1B1 |
2.02264 |
|
[BP] GO:0046686 |
response to cadmium ion
|
CYP1A2, EGFR, MMP9, TERT |
2.02243 |
|
[BP] GO:2001242 |
regulation of intrinsic apoptotic signaling pathway
|
BCL2, HSPA1A, MIF, MMP9, PTPN1, SRC |
2.01921 |
|
[BP] GO:0072593 |
reactive oxygen species metabolic process
|
BCL2, CYP1A1, CYP1A2, CYP1B1, EGFR |
2.01687 |
|
[BP] GO:0051271 |
None
|
ADORA1, ADORA3, APEX1, BCL2, CYP19A1, CYP1B1, DRD2, MIF |
2.00978 |
|
[BP] GO:0001952 |
regulation of cell-matrix adhesion
|
BCL2, KDR, SMAD3, SRC, TEK |
2.00392 |
|
[BP] GO:0014013 |
None
|
APP, DRD3, F2, RELA, TERT |
2.00392 |
|
[BP] GO:0097553 |
None
|
DRD2, HTR2A, HTR2B, HTR2C |
2.00392 |
|
[BP] GO:0072347 |
None
|
CNR1, DRD2, DRD3, RELA |
2.00392 |
|
[BP] GO:1903391 |
regulation of adherens junction organization
|
KDR, SMAD3, SRC, TEK |
2.00392 |
|
[BP] GO:0021853 |
None
|
DRD1, DRD2 |
2.00392 |
|
[BP] GO:0098501 |
polynucleotide dephosphorylation
|
APEX1, POLB |
2.00392 |
|
[BP] GO:0061370 |
testosterone biosynthetic process
|
CYP19A1, HSD17B3 |
2.00392 |
|
[BP] GO:0010641 |
None
|
F3, SRC |
2.00392 |
|
[BP] GO:0090325 |
None
|
DRD2, DRD3 |
2.00392 |
|
[BP] GO:0007598 |
None
|
F10, F3 |
2.00392 |
|
[BP] GO:1904936 |
None
|
DRD1, DRD2 |
2.00392 |
|
[BP] GO:0042321 |
None
|
ADORA1, DRD2 |
2.00392 |
|
[CC] GO:0031226 |
intrinsic component of plasma membrane
|
ADORA1, ADORA3, ADRA1A, ADRA2A, APP, AXL, CA4, CHRM2, CNR1, CNR2, DRD1, DRD2, DRD3, F10, F3, FLT3, GPR35, HTR1A, HTR2A, HTR2B, HTR2C, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, MTNR1A, MTNR1B, SIGMAR1, SLC6A2, SLC6A4, TEK |
9.42144 |
|
[CC] GO:0005887 |
integral component of plasma membrane
|
ADORA1, ADORA3, ADRA1A, ADRA2A, APP, AXL, CHRM2, CNR1, CNR2, DRD1, DRD2, DRD3, FLT3, GPR35, HTR1A, HTR2A, HTR2B, HTR2C, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, MTNR1A, MTNR1B, SIGMAR1, SLC6A2, SLC6A4, TEK |
7.99519 |
|
[CC] GO:0044459 |
plasma membrane part
|
ABCG2, ADORA1, ADORA3, ADRA1A, ADRA2A, APP, AXL, CA2, CA4, CA9, CACNA1C, CHRM2, CNR1, CNR2, DRD1, DRD2, DRD3, DUSP3, EGFR, F10, F2, F3, FLT3, GPR35, HTR1A, HTR2A, HTR2B, HTR2C, HTR5A, HTR6, HTR7, IGF1R, INSR, KCNH2, KDR, MET, MTNR1A, MTNR1B, SIGMAR1, SLC6A2, SLC6A4, SRC, TEK |
7.84941 |
|
[CC] GO:0005886 |
plasma membrane
|
ABCG2, ACHE, ADORA1, ADORA3, ADRA1A, ADRA2A, ALPL, APP, AR, AXL, CA12, CA14, CA2, CA4, CA9, CACNA1C, CHRM2, CNR1, CNR2, CSNK2A1, DRD1, DRD2, DRD3, EGFR, ESR1, F10, F2, F3, FLT3, GLO1, GPR35, HTR1A, HTR2A, HTR2B, HTR2C, HTR5A, HTR6, HTR7, IGF1R, INSR, KCNH2, KDR, MAP2K1, MAP3K7, MET, MMP2, MTNR1A, MTNR1B, PIM1, PTPN1, SLC6A2, SLC6A4, SMAD3, SRC, TEK, TERT |
7.45571 |
|
[CC] GO:0016020 |
membrane
|
ABCG2, ACHE, ADORA1, ADORA3, ADRA1A, ADRA2A, ALOX5, ALPL, APP, AR, AXL, BCL2, CA12, CA14, CA2, CA4, CA9, CACNA1C, CHRM2, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, CYP3A4, DRD1, DRD2, DRD3, EGFR, ESR1, F10, F2, F3, FLT3, FUT7, GLO1, GPR35, HMGCR, HSD17B2, HSD17B3, HTR1A, HTR2A, HTR2B, HTR2C, HTR5A, HTR6, HTR7, IGF1R, INSR, KCNH2, KDR, MAOA, MAP2K1, MAP3K7, MET, MMP2, MTNR1A, MTNR1B, PIM1, PTGES, PTPN1, SIGMAR1, SLC6A2, SLC6A4, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TYR |
6.4752 |
|
[CC] GO:0044425 |
membrane part
|
ABCG2, ACHE, ADORA1, ADORA3, ADRA1A, ADRA2A, ALPL, APP, AXL, BCL2, CA12, CA14, CA2, CA4, CA9, CACNA1C, CHRM2, CNR1, CNR2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, CYP3A4, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, F10, F2, F3, FLT3, FUT7, GPR35, HMGCR, HSD17B2, HSD17B3, HTR1A, HTR2A, HTR2B, HTR2C, HTR5A, HTR6, HTR7, IGF1R, INSR, KCNH2, KDR, MAOA, MET, MTNR1A, MTNR1B, PTGES, PTPN1, SIGMAR1, SLC6A2, SLC6A4, SRC, TBXAS1, TEK, TYR |
4.58606 |
|
[CC] GO:0044444 |
cytoplasmic part
|
ABCG2, ACHE, ADORA1, ADRA1A, AKR1B1, AKR1B10, ALOX5, AOX1, APEX1, APP, AR, AURKB, BCL2, CA1, CA2, CA3, CA4, CA5A, CA5B, CA7, CACNA1C, CDC25B, CES1, CES2, CHRM2, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, CYP3A4, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, F10, F2, FABP3, FABP4, FLT3, FUT7, GLO1, HMGCR, HSD17B1, HSD17B2, HSD17B3, HSPA1A, HTR2A, HTR5A, INSR, KCNH2, KDR, MAOA, MAP2K1, MAP3K7, MIF, MMP2, MMP9, PIM1, POLA1, PTGES, PTPN1, RELA, SIGMAR1, SLC6A4, SMAD3, SRC, TBXAS1, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
4.23553 |
|
[CC] GO:0045121 |
membrane raft
|
ADRA1A, APP, CNR1, EGFR, HTR2A, INSR, KDR, SLC6A2, SLC6A4, SRC, TEK |
4.14044 |
|
[CC] GO:0044432 |
endoplasmic reticulum part
|
APP, BCL2, CES1, CES2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, CYP3A4, DRD1, EGFR, F10, F2, FLT3, HMGCR, HSD17B2, HSD17B3, PTGES, PTPN1, SIGMAR1, TBXAS1 |
4.14044 |
|
[CC] GO:0098857 |
membrane microdomain
|
ADRA1A, APP, CNR1, EGFR, HTR2A, INSR, KDR, SLC6A2, SLC6A4, SRC, TEK |
4.12229 |
|
[CC] GO:0005783 |
None
|
ADORA1, APEX1, APP, BCL2, CA4, CES1, CES2, CYP19A1, CYP2D6, FLT3, HMGCR, HSD17B3, HSPA1A, HTR5A, KDR, MAP2K1, PTPN1, SIGMAR1, XDH |
3.94674 |
|
[CC] GO:0098589 |
membrane region
|
ADRA1A, APP, CNR1, EGFR, HTR2A, INSR, KDR, SLC6A2, SLC6A4, SRC, TEK |
3.44895 |
|
[CC] GO:0005641 |
nuclear envelope lumen
|
ALOX5, APP, PTGES |
3.26182 |
|
[CC] GO:0098590 |
plasma membrane region
|
ABCG2, ADORA1, ADRA1A, ADRA2A, CA2, CA4, CA9, CHRM2, CNR1, DRD1, DRD2, EGFR, HTR2A, INSR, MET, SIGMAR1, SRC, TEK |
3.2019 |
|
[CC] GO:0031224 |
None
|
ABCG2, ACHE, ADORA1, ADORA3, ADRA1A, ADRA2A, ALPL, APP, AXL, CA12, CA14, CA4, CA9, CACNA1C, CHRM2, CNR1, CNR2, CYP3A4, DRD1, DRD2, DRD3, EGFR, ESR1, F10, F3, FLT3, FUT7, GPR35, HMGCR, HSD17B2, HTR1A, HTR2A, HTR2B, HTR2C, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MAOA, MET, MTNR1A, MTNR1B, PTGES, SIGMAR1, SLC6A2, SLC6A4, TBXAS1, TEK, TYR |
2.97809 |
|
[CC] GO:0043227 |
membrane-bounded organelle
|
ABCG2, ACHE, ADORA1, ADRA1A, AKR1B1, AKR1B10, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CA1, CA2, CA4, CA5A, CA5B, CA6, CES1, CES2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, CYP3A4, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FABP3, FABP4, FLT3, FUT7, GLO1, HMGCR, HSD17B3, HSPA1A, HTR2A, HTR5A, IGF1R, INSR, KDR, MAOA, MAP2K1, MAP3K7, MIF, MMP12, MMP2, MMP9, NUAK1, PIM1, POLA1, POLB, PPARA, PTPN1, RELA, RORC, SHBG, SIGMAR1, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
2.9586 |
|
[CC] GO:0043226 |
organelle
|
ABCG2, ACHE, ADORA1, ADRA1A, AKR1B1, AKR1B10, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CA1, CA2, CA4, CA5A, CA5B, CA6, CA9, CACNA1C, CES1, CES2, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, CYP3A4, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FABP3, FABP4, FLT3, FUT7, GLO1, HMGCR, HSD17B3, HSPA1A, HTR2A, HTR5A, HTR6, IGF1R, INSR, KDR, MAOA, MAP2K1, MAP3K7, MIF, MMP12, MMP2, MMP9, NUAK1, PIM1, POLA1, POLB, PPARA, PTPN1, RELA, RORC, SHBG, SIGMAR1, SMAD3, SRC, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
2.5461 |
|
[CC] GO:0005789 |
endoplasmic reticulum membrane
|
BCL2, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, CYP3A4, DRD1, EGFR, HMGCR, HSD17B2, HSD17B3, PTGES, SIGMAR1, TBXAS1 |
2.53502 |
|
[CC] GO:0016323 |
basolateral plasma membrane
|
ADORA1, ADRA2A, CA2, CA4, CA9, EGFR, TEK |
2.42079 |
|
[CC] GO:0016021 |
None
|
ABCG2, ADORA1, ADORA3, ADRA1A, ADRA2A, ALPL, APP, AXL, CA12, CA14, CA9, CACNA1C, CHRM2, CNR1, CNR2, CYP3A4, DRD1, DRD2, DRD3, EGFR, ESR1, F3, FLT3, FUT7, GPR35, HMGCR, HSD17B2, HTR1A, HTR2A, HTR2B, HTR2C, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MAOA, MET, MTNR1A, MTNR1B, PTGES, SIGMAR1, SLC6A2, SLC6A4, TBXAS1, TEK, TYR |
2.34542 |
|
[CC] GO:0044464 |
cell part
|
ABCG2, ACHE, ADORA1, ADORA3, ADRA1A, ADRA2A, AKR1B1, AKR1B10, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA7, CA9, CACNA1C, CDC25B, CES1, CES2, CHRM2, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, CYP3A4, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F2, F3, FABP3, FABP4, FLT3, FUT7, GLO1, GPR35, HMGCR, HSD17B1, HSD17B2, HSD17B3, HSPA1A, HTR1A, HTR2A, HTR2B, HTR2C, HTR5A, HTR6, HTR7, IGF1R, INSR, KCNH2, KDR, MAOA, MAP2K1, MAP3K7, MET, MIF, MMP12, MMP2, MMP9, MTNR1A, MTNR1B, NUAK1, PIM1, POLA1, POLB, PPARA, PTGES, PTPN1, RELA, RORC, SIGMAR1, SLC6A2, SLC6A4, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
2.27805 |
|
[CC] GO:0031233 |
None
|
CA4, F10, F3 |
2.17988 |
|
[CC] GO:0044454 |
None
|
APEX1, AR, AURKB, CSNK2A1, ESR1, POLA1, RELA, SMAD3, TERT, TNKS, TNKS2 |
2.09665 |
|
[CC] GO:0009986 |
cell surface
|
ACHE, APP, AXL, CA4, EGFR, F3, KCNH2, MET, MIF, SLC6A2, TEK |
2.0391 |
|
[MF] GO:0004089 |
carbonate dehydratase activity
|
CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9 |
17.4627 |
|
[MF] GO:0043167 |
ion binding
|
ABCG2, ACHE, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CACNA1C, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, CYP3A4, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F2, F3, FABP3, FABP4, FLT3, GLO1, HMGCR, HSD17B1, HSPA1A, HTR1A, HTR2A, HTR2B, HTR2C, HTR5A, HTR7, IGF1R, INSR, KDR, MAP2K1, MAP3K7, MET, MMP1, MMP12, MMP2, MMP9, NUAK1, PIM1, POLA1, POLB, PPARA, PTGES, PTPN1, RELA, RORC, SLC6A2, SLC6A4, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
17.4627 |
|
[MF] GO:0046914 |
transition metal ion binding
|
ALOX5, AOX1, APP, AR, CA1, CA12, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, CYP3A4, ESR1, ESR2, ESRRA, ESRRB, GLO1, MMP1, MMP12, MMP2, MMP9, PIM1, PPARA, PTPN1, RORC, SMAD3, TBXAS1, TNKS, TYR, XDH |
16.9431 |
|
[MF] GO:0038023 |
signaling receptor activity
|
ADORA1, ADORA3, ADRA1A, ADRA2A, AR, AXL, CHRM2, CNR1, CNR2, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FLT3, GPR35, HTR1A, HTR2A, HTR2B, HTR2C, HTR5A, HTR6, HTR7, IGF1R, INSR, KCNH2, KDR, MET, MTNR1A, MTNR1B, PPARA, RORC, SIGMAR1, TEK |
13.6966 |
|
[MF] GO:0043169 |
cation binding
|
ACHE, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CACNA1C, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, CYP3A4, DRD1, DRD2, DRD3, ESR1, ESR2, ESRRA, ESRRB, F10, F2, GLO1, HTR1A, HTR2A, HTR2B, HTR2C, HTR5A, HTR7, MAP3K7, MMP1, MMP12, MMP2, MMP9, NUAK1, PIM1, POLA1, POLB, PPARA, PTPN1, RORC, SLC6A2, SLC6A4, SMAD3, TBXAS1, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
13.0987 |
|
[MF] GO:0004871 |
signal transducer activity
|
ADORA1, ADORA3, ADRA1A, ADRA2A, AR, AXL, CHRM2, CNR1, CNR2, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FLT3, GPR35, HTR1A, HTR2A, HTR2B, HTR2C, HTR5A, HTR6, HTR7, IGF1R, INSR, KCNH2, KDR, MAP2K1, MAP3K7, MET, MTNR1A, MTNR1B, PPARA, RORC, SIGMAR1, SMAD3, TEK |
12.9671 |
|
[MF] GO:0016835 |
carbon-oxygen lyase activity
|
APEX1, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, POLB |
12.3855 |
|
[MF] GO:0004872 |
receptor activity
|
ADORA1, ADORA3, ADRA1A, ADRA2A, AR, AXL, CHRM2, CNR1, CNR2, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FLT3, GPR35, HTR1A, HTR2A, HTR2B, HTR2C, HTR5A, HTR6, HTR7, IGF1R, INSR, KCNH2, KDR, MET, MTNR1A, MTNR1B, PPARA, RORC, SIGMAR1, TEK |
12.1726 |
|
[MF] GO:0060089 |
molecular transducer activity
|
ADORA1, ADORA3, ADRA1A, ADRA2A, AR, AXL, CHRM2, CNR1, CNR2, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F2, F3, FLT3, GPR35, HTR1A, HTR2A, HTR2B, HTR2C, HTR5A, HTR6, HTR7, IGF1R, INSR, KCNH2, KDR, MET, MTNR1A, MTNR1B, PPARA, RORC, SIGMAR1, TEK |
11.7762 |
|
[MF] GO:0003824 |
catalytic activity
|
ABCG2, ACHE, ADORA1, AKR1B1, AKR1B10, ALOX5, ALPL, AOX1, APEX1, AURKB, AXL, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CDC25B, CES1, CES2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, CYP3A4, DUSP3, EGFR, F10, F2, F3, FLT3, FUT7, GLO1, HMGCR, HSD17B1, HSD17B2, HSD17B3, HSPA1A, IGF1R, INSR, KCNH2, KDR, MAOA, MAP2K1, MAP3K7, MET, MIF, MMP1, MMP12, MMP2, MMP9, NUAK1, PIM1, POLA1, POLB, PTGES, PTPN1, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
11.2452 |
|
[MF] GO:0016836 |
hydro-lyase activity
|
CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9 |
11.0479 |
|
[MF] GO:0008227 |
None
|
ADRA1A, ADRA2A, CHRM2, DRD2, HTR1A, HTR2A, HTR2B, HTR2C, HTR5A, HTR6, HTR7 |
10.8773 |
|
[MF] GO:0070405 |
ammonium ion binding
|
ACHE, DRD1, DRD2, DRD3, HTR1A, HTR2A, HTR2B, HTR2C, HTR5A, HTR7, SLC6A4 |
9.71939 |
|
[MF] GO:0008144 |
drug binding
|
ABCG2, ACHE, AURKB, AXL, CHRM2, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, CYP3A4, DRD1, DRD2, DRD3, EGFR, FLT3, HSPA1A, HTR2A, HTR2B, HTR2C, IGF1R, INSR, KDR, MAP2K1, MAP3K7, MET, NUAK1, PIM1, PPARA, SIGMAR1, SLC6A4, SRC, TEK, TOP2A |
9.53917 |
|
[MF] GO:0016829 |
lyase activity
|
APEX1, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, GLO1, POLB |
8.95671 |
|
[MF] GO:0008270 |
zinc ion binding
|
AR, CA1, CA12, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, ESR1, ESR2, ESRRA, ESRRB, GLO1, MMP1, MMP12, MMP2, MMP9, PPARA, PTPN1, RORC, SMAD3, TNKS |
8.82361 |
|
[MF] GO:0099600 |
transmembrane receptor activity
|
ADORA1, ADORA3, ADRA1A, ADRA2A, AXL, CHRM2, CNR1, CNR2, DRD1, DRD2, DRD3, EGFR, F3, FLT3, GPR35, HTR1A, HTR2A, HTR2B, HTR2C, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, MTNR1A, MTNR1B, SIGMAR1, TEK |
8.43089 |
|
[MF] GO:0004888 |
transmembrane signaling receptor activity
|
ADORA1, ADORA3, ADRA1A, ADRA2A, AXL, CHRM2, CNR1, CNR2, DRD1, DRD2, DRD3, EGFR, F3, FLT3, GPR35, HTR1A, HTR2A, HTR2B, HTR2C, HTR5A, HTR6, HTR7, IGF1R, INSR, KDR, MET, MTNR1A, MTNR1B, SIGMAR1, TEK |
8.43089 |
|
[MF] GO:0043176 |
None
|
HTR1A, HTR2A, HTR2B, HTR2C, HTR5A, HTR7 |
8.36171 |
|
[MF] GO:0051378 |
None
|
HTR1A, HTR2A, HTR2B, HTR2C, HTR5A, HTR7 |
8.36171 |
|
[MF] GO:0030594 |
None
|
CHRM2, DRD1, DRD2, DRD3, HTR1A, HTR2A, HTR2B, HTR2C, HTR5A, HTR6, HTR7 |
8.05685 |
|
[MF] GO:0099528 |
None
|
CHRM2, HTR1A, HTR2A, HTR2B, HTR2C, HTR5A, HTR6, HTR7 |
8.00481 |
|
[MF] GO:0046872 |
metal ion binding
|
ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CACNA1C, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, CYP3A4, ESR1, ESR2, ESRRA, ESRRB, F10, F2, GLO1, MAP3K7, MMP1, MMP12, MMP2, MMP9, NUAK1, PIM1, POLA1, POLB, PPARA, PTPN1, RORC, SLC6A2, SLC6A4, SMAD3, TBXAS1, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
7.95729 |
|
[MF] GO:0004993 |
None
|
HTR1A, HTR2A, HTR2B, HTR2C, HTR5A, HTR6, HTR7 |
7.90293 |
|
[MF] GO:0099589 |
None
|
HTR1A, HTR2A, HTR2B, HTR2C, HTR5A, HTR6, HTR7 |
7.90293 |
|
[MF] GO:0005496 |
steroid binding
|
AR, CYP3A4, ESR1, ESR2, ESRRA, ESRRB, HSD17B1, RORC, SHBG |
6.60146 |
|
[MF] GO:0005506 |
iron ion binding
|
ALOX5, AOX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, CYP3A4, TBXAS1, XDH |
6.50179 |
|
[MF] GO:0004714 |
transmembrane receptor protein tyrosine kinase activity
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, TEK |
6.44796 |
|
[MF] GO:0070330 |
aromatase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, CYP3A4 |
6.36852 |
|
[MF] GO:0004497 |
monooxygenase activity
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, CYP3A4, TBXAS1, TYR |
6.26382 |
|
[MF] GO:0016491 |
oxidoreductase activity
|
AKR1B1, AKR1B10, ALOX5, AOX1, APEX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, CYP3A4, HMGCR, HSD17B1, HSD17B2, HSD17B3, MAOA, TBXAS1, TYR, XDH |
6.10304 |
|
[MF] GO:0019825 |
oxygen binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, CYP3A4 |
6.05472 |
|
[MF] GO:0016712 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2D6, CYP3A4 |
6.05017 |
|
[MF] GO:0098531 |
transcription factor activity, direct ligand regulated sequence-specific DNA binding
|
AR, ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC |
5.81719 |
|
[MF] GO:0004879 |
nuclear receptor activity
|
AR, ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC |
5.81719 |
|
[MF] GO:0019199 |
transmembrane receptor protein kinase activity
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MET, TEK |
5.69312 |
|
[MF] GO:0042165 |
neurotransmitter binding
|
ACHE, HTR1A, HTR2A, HTR2B, HTR2C, HTR5A, HTR7 |
5.66491 |
|
[MF] GO:0004930 |
None
|
ADORA1, ADORA3, ADRA1A, ADRA2A, CHRM2, CNR1, CNR2, DRD1, DRD2, DRD3, GPR35, HTR1A, HTR2A, HTR2B, HTR2C, HTR5A, HTR6, HTR7, MTNR1A, MTNR1B, SIGMAR1 |
5.59753 |
|
[MF] GO:0042562 |
hormone binding
|
ACHE, AR, EGFR, HSD17B1, IGF1R, INSR, MTNR1A, SHBG |
5.4758 |
|
[MF] GO:0003707 |
steroid hormone receptor activity
|
AR, ESR1, ESR2, ESRRA, ESRRB, PPARA, RORC |
5.33361 |
|
[MF] GO:0020037 |
heme binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, CYP3A4, SRC, TBXAS1 |
5.27372 |
|
[MF] GO:0004713 |
protein tyrosine kinase activity
|
AXL, EGFR, FLT3, IGF1R, INSR, KDR, MAP2K1, MET, SRC, TEK |
5.059 |
|
[MF] GO:0046906 |
tetrapyrrole binding
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, CYP3A4, SRC, TBXAS1 |
5.0239 |
|
[MF] GO:0048037 |
cofactor binding
|
AOX1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, CYP3A4, HMGCR, HSD17B1, POLA1, PTGES, SRC, TBXAS1, XDH |
4.98477 |
|
[MF] GO:0032403 |
protein complex binding
|
ACHE, ADORA1, ADRA2A, APEX1, EGFR, ESRRB, FLT3, HTR2A, IGF1R, INSR, KDR, MMP12, MMP9, PPARA, PTPN1, RELA, SLC6A4, SMAD3, SRC |
4.95061 |
|
[MF] GO:0044877 |
macromolecular complex binding
|
ACHE, ADORA1, ADRA2A, APEX1, CSNK2A1, EGFR, ESRRB, FLT3, HTR2A, IGF1R, INSR, KDR, MMP12, MMP9, PIM1, PPARA, PTPN1, RELA, SLC6A4, SMAD3, SRC |
4.79027 |
|
[MF] GO:0016705 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
|
CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, CYP3A4, TBXAS1, TYR |
4.64115 |
|
[MF] GO:0042802 |
identical protein binding
|
ABCG2, ACHE, ADRA2A, AOX1, APP, BCL2, CSNK2A1, DRD2, EGFR, ESR1, ESR2, FLT3, HMGCR, IGF1R, KCNH2, KDR, MAP3K7, MET, MIF, MMP9, RELA, SLC6A4, SMAD3, TERT, TOP2A, TYR, XDH |
4.51611 |
|
[MF] GO:0019899 |
enzyme binding
|
ADRA2A, APP, AR, AURKB, BCL2, CDC25B, CYP1A1, CYP1A2, CYP2C19, CYP3A4, DUSP3, EGFR, ESR1, ESR2, ESRRB, F3, HMGCR, HSPA1A, KCNH2, MET, MIF, POLA1, POLB, PPARA, PTPN1, RELA, SLC6A4, SMAD3, SRC, TEK, TNKS2, TOP2A |
4.50219 |
|
[MF] GO:0097159 |
organic cyclic compound binding
|
ABCG2, ADORA1, ADRA2A, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, CYP3A4, DRD1, DRD2, DRD3, EGFR, ESR1, ESR2, ESRRA, ESRRB, FLT3, HMGCR, HSD17B1, HSPA1A, HTR1A, HTR2A, HTR2B, HTR2C, HTR5A, HTR7, IGF1R, INSR, KDR, MAP2K1, MAP3K7, MET, MMP12, MTNR1A, NUAK1, PIM1, POLA1, POLB, PPARA, PTPN1, RELA, RORC, SHBG, SLC6A4, SMAD3, SRC, TBXAS1, TEK, TERT, TOP2A, XDH |
4.37282 |
|
[MF] GO:0004672 |
protein kinase activity
|
AURKB, AXL, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KCNH2, KDR, MAP2K1, MAP3K7, MET, NUAK1, PIM1, SRC, TEK |
4.13451 |
|
[MF] GO:0016614 |
oxidoreductase activity, acting on CH-OH group of donors
|
AKR1B1, AKR1B10, AOX1, HMGCR, HSD17B1, HSD17B2, HSD17B3, XDH |
4.0847 |
|
[MF] GO:0008395 |
steroid hydroxylase activity
|
CYP19A1, CYP1A1, CYP2C19, CYP2D6, CYP3A4 |
4.02147 |
|
[MF] GO:0008289 |
lipid binding
|
AR, AXL, CYP3A4, ESR1, ESR2, ESRRA, ESRRB, F10, F2, F3, FABP3, FABP4, HSD17B1, PPARA, RORC, SHBG |
3.9651 |
|
[MF] GO:1901338 |
None
|
ADRA2A, DRD1, DRD2, DRD3 |
3.55226 |
|
[MF] GO:0016772 |
transferase activity, transferring phosphorus-containing groups
|
AURKB, AXL, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KCNH2, KDR, MAP2K1, MAP3K7, MET, NUAK1, PIM1, POLA1, POLB, SRC, TEK, TERT |
3.54041 |
|
[MF] GO:0046983 |
protein dimerization activity
|
ABCG2, ACHE, ADORA1, ADRA1A, ADRA2A, AOX1, AR, AXL, BCL2, DRD2, EGFR, FLT3, HMGCR, KCNH2, RELA, SLC6A4, SMAD3, TERT, TOP2A, TYR, XDH |
3.31695 |
|
[MF] GO:0016773 |
phosphotransferase activity, alcohol group as acceptor
|
AURKB, AXL, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KCNH2, KDR, MAP2K1, MAP3K7, MET, NUAK1, PIM1, SRC, TEK |
3.24096 |
|
[MF] GO:0042803 |
protein homodimerization activity
|
ABCG2, ACHE, ADRA2A, AOX1, BCL2, DRD2, FLT3, HMGCR, KCNH2, RELA, SLC6A4, SMAD3, TERT, TOP2A, TYR, XDH |
3.18285 |
|
[MF] GO:0016725 |
oxidoreductase activity, acting on CH or CH2 groups
|
CYP1A2, CYP3A4, XDH |
3.10446 |
|
[MF] GO:0004716 |
signal transducer, downstream of receptor, with protein tyrosine kinase activity
|
EGFR, INSR, KDR |
3.10446 |
|
[MF] GO:0003674 |
molecular_function
|
ABCG2, ACHE, ADORA1, ADORA3, ADRA1A, ADRA2A, AKR1B1, AKR1B10, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CACNA1C, CDC25B, CES1, CES2, CHRM2, CNR1, CNR2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, CYP3A4, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F2, F3, FABP3, FABP4, FLT3, FUT7, GLO1, GPR35, HMGCR, HSD17B1, HSD17B2, HSD17B3, HSPA1A, HTR1A, HTR2A, HTR2B, HTR2C, HTR5A, HTR6, HTR7, IGF1R, INSR, KCNH2, KDR, MAOA, MAP2K1, MAP3K7, MET, MIF, MMP1, MMP12, MMP2, MMP9, MTNR1A, MTNR1B, NUAK1, PIM1, POLA1, POLB, PPARA, PTGES, PTPN1, RELA, RORC, SHBG, SIGMAR1, SLC6A2, SLC6A4, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
3.04641 |
|
[MF] GO:0016301 |
kinase activity
|
AURKB, AXL, CSNK2A1, EGFR, FLT3, IGF1R, INSR, KCNH2, KDR, MAP2K1, MAP3K7, MET, NUAK1, PIM1, SRC, TEK |
2.83023 |
|
[MF] GO:0038052 |
RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding
|
ESR1, ESR2 |
2.82915 |
|
[MF] GO:0071886 |
None
|
HTR2A, HTR2C |
2.82915 |
|
[MF] GO:0004952 |
None
|
DRD1, DRD2, DRD3 |
2.76767 |
|
[MF] GO:0019902 |
phosphatase binding
|
BCL2, EGFR, HMGCR, MET, PPARA, PTPN1, SMAD3 |
2.70898 |
|
[MF] GO:0035240 |
None
|
DRD1, DRD2, DRD3 |
2.67005 |
|
[MF] GO:0016616 |
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
|
AKR1B1, AKR1B10, HMGCR, HSD17B1, HSD17B2, HSD17B3 |
2.57988 |
|
[MF] GO:0005057 |
signal transducer activity, downstream of receptor
|
EGFR, INSR, KDR, MAP2K1, MAP3K7, SMAD3 |
2.52773 |
|
[MF] GO:1901363 |
heterocyclic compound binding
|
ABCG2, ADORA1, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, CYP3A4, EGFR, ESR1, ESR2, ESRRA, ESRRB, FLT3, HMGCR, HSD17B1, HSPA1A, HTR1A, HTR2A, HTR2B, HTR2C, HTR5A, HTR7, IGF1R, INSR, KDR, MAP2K1, MAP3K7, MET, MMP12, NUAK1, PIM1, POLA1, POLB, PPARA, PTPN1, RELA, RORC, SLC6A4, SMAD3, SRC, TBXAS1, TEK, TERT, TOP2A, XDH |
2.50515 |
|
[MF] GO:0008502 |
None
|
MTNR1A, MTNR1B |
2.43 |
|
[MF] GO:0070576 |
vitamin D 24-hydroxylase activity
|
CYP1A1, CYP3A4 |
2.43 |
|
[MF] GO:0004949 |
None
|
CNR1, CNR2 |
2.43 |
|
[MF] GO:0005330 |
None
|
SLC6A2, SLC6A4 |
2.43 |
|
[MF] GO:0047374 |
None
|
CES1, CES2 |
2.43 |
|
[MF] GO:0004935 |
None
|
ADRA1A, ADRA2A, DRD2 |
2.43 |
|
[MF] GO:0016788 |
None
|
ACHE, ADORA1, ALPL, APEX1, CA1, CA2, CA3, CDC25B, CES1, CES2, DUSP3, MAP2K1, POLA1, PTPN1 |
2.39058 |
|
[MF] GO:0016903 |
None
|
AKR1B1, AKR1B10, AOX1, XDH |
2.3616 |
|
[MF] GO:0046982 |
protein heterodimerization activity
|
ADORA1, ADRA1A, ADRA2A, AXL, BCL2, DRD2, EGFR, RELA, SMAD3, TOP2A, TYR |
2.30589 |
|
[MF] GO:0008134 |
transcription factor binding
|
APEX1, AR, BCL2, ESR1, ESRRB, FLT3, PIM1, PPARA, RELA, SMAD3, SRC, TERT |
2.27612 |
|
[MF] GO:0005488 |
binding
|
ABCG2, ACHE, ADORA1, ADRA1A, ADRA2A, AKR1B10, ALOX5, ALPL, AOX1, APEX1, APP, AR, AURKB, AXL, BCL2, CA1, CA12, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA9, CACNA1C, CDC25B, CHRM2, CNR1, CSNK2A1, CYP19A1, CYP1A1, CYP1A2, CYP1B1, CYP2C19, CYP2D6, CYP3A4, DRD1, DRD2, DRD3, DUSP3, EGFR, ESR1, ESR2, ESRRA, ESRRB, F10, F2, F3, FABP3, FABP4, FLT3, GLO1, HMGCR, HSD17B1, HSPA1A, HTR1A, HTR2A, HTR2B, HTR2C, HTR5A, HTR6, HTR7, IGF1R, INSR, KCNH2, KDR, MAP2K1, MAP3K7, MET, MIF, MMP1, MMP12, MMP2, MMP9, MTNR1A, MTNR1B, NUAK1, PIM1, POLA1, POLB, PPARA, PTGES, PTPN1, RELA, RORC, SHBG, SIGMAR1, SLC6A2, SLC6A4, SMAD3, SRC, TBXAS1, TEK, TERT, TNKS, TNKS2, TOP2A, TYR, XDH |
2.23718 |
|
[MF] GO:0034056 |
estrogen response element binding
|
ESR1, ESR2 |
2.17988 |
|
[MF] GO:0034875 |
caffeine oxidase activity
|
CYP1A2, CYP3A4 |
2.17988 |
|
[MF] GO:0032795 |
None
|
ADORA1, ADRA2A |
2.17988 |
|
[MF] GO:0005497 |
None
|
AR, SHBG |
2.17988 |
|
[MF] GO:0051425 |
None
|
APP, INSR |
2.17988 |
|
[MF] GO:0033695 |
oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor
|
CYP1A2, CYP3A4 |
2.17988 |
|
[MF] GO:0001223 |
transcription coactivator binding
|
ESR1, PPARA, TERT |
2.17988 |
|
[MF] GO:0017171 |
serine hydrolase activity
|
ACHE, F10, F2, F3, MMP1, MMP12, MMP2, MMP9 |
2.1202 |
|
[MF] GO:0043168 |
anion binding
|
ABCG2, AOX1, APP, AURKB, AXL, CSNK2A1, EGFR, F10, F2, F3, FABP3, FABP4, FLT3, HMGCR, HSD17B1, HSPA1A, IGF1R, INSR, KDR, MAP2K1, MAP3K7, MET, NUAK1, PIM1, PTGES, RELA, SRC, TEK, TOP2A, XDH |
2.00985 |
|
[MF] GO:0101020 |
estrogen 16-alpha-hydroxylase activity
|
CYP1A1, CYP3A4 |
2.00392 |
|
[MF] GO:0030284 |
estrogen receptor activity
|
ESR1, ESR2 |
2.00392 |
|
[MF] GO:0043559 |
insulin binding
|
IGF1R, INSR |
2.00392 |
