TCM Prescription: Fu Fang Huang Lian Su Tablets



Prescription Description
Prescription IDTCMFx3585
Pinyin NameFu Fang Huang Lian Su Pian
Chinese Name复方黄连素片
English NameFu Fang Huang Lian Su Tablets
Function Description腹泻, 痢疾
IndicationsDysentery disorder, Diarrhea, Dysentery
Disease ICD-11 Category SA56 [Dysentery disorder (TM1), 痢疾 (TM1) ];
ME05.1 [Diarrhoea, 腹泻 ];
1A40.Z [Infectious gastroenteritis or colitis without specification of infectious agent, 未特指感染性病原体的感染性胃肠炎或结肠炎 ];
Human Tissues Associated with IndicationIntestine, Stomach
ReferenceCFDA
Reference Book/linkhttp://samr.cfda.gov.cn/WS01/CL0001/
Prescription Components
Component ID Latin Name Chinese Name Component Quantity Barcode
TCMH2402 NA 盐酸小檗碱 TCMH2402
TCMH1533 Saussurea lappa 木香 TCMH1533
TCMH104 Paeonia lactiflora 白芍 TCMH104 ITSAH2416-14
TCMH2216 Evodia rutaecarpa 吴茱萸 TCMH2216
Reference: CFDA

Targeted Human Proteins by the Ingredients of Prescription

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT2 MAPT Microtubule-associated protein tau Unclassified P10636
TCMT313 HTR2B Serotonin 2b (5-HT2b) receptor GPCR P41595
TCMT314 HTR2C Serotonin 2c (5-HT2c) receptor GPCR P28335
TCMT315 HTR6 Serotonin 6 (5-HT6) receptor GPCR P50406
TCMT316 MTNR1A Melatonin receptor 1A GPCR P48039
TCMT317 MTNR1B Melatonin receptor 1B GPCR P49286
TCMT37 HTR2A Serotonin 2a (5-HT2a) receptor GPCR P28223
TCMT560 F10 Coagulation factor X Unclassified P00742
TCMT609 CTSL Cathepsin L Unclassified P07711


Targeted Pathogenic Microbes by the Ingredients of Prescription

Target ID Target Name
TCMT1189 Pseudomonas fluorescens
TCMT1218 Staphylococcus aureus
TCMT1219 Enterococcus
TCMT1222 Plasmodium falciparum D6
TCMT1229 Enterococcus faecalis
TCMT1251 Candida albicans
TCMT1255 Human immunodeficiency virus 1
TCMT1318 Human T-lymphotropic virus 1
TCMT1438 Plasmodium falciparum
TCMT1454 Bacillus subtilis
TCMT1462 Streptococcus mutans
TCMT1463 Mycobacterium tuberculosis
TCMT1465 Entamoeba histolytica

Gene Ontology Associated to Targeted Human Proteins

GO Term GO Name Enriched Genes Log10 Adjusted P-value


KEGG Pathways Associated to Targeted Human Proteins

KEGG Pathway ID Enriched Genes Log10 Adjusted P-value


Target Exprsssion in Healthy Human Tissues (protein & mRNA level)

Protein expression data was from the "Human Proteome Map" dataset
mRNA expression data was from the "GTEx" dataset



Average Target Expression (Fold Change) in Multiple Disease Conditions

Fold Change with Corresponding Normal Samples
Click each cell within the heatmap to access gene expression of individual patient samples
Data Section
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1. General Information of Prescription  
2. Putative Targets  
3. Activity & References for Filtering Putative Targets  
4. GO & Pathway