Component: Poncirus trifoliata 绿衣枳实


Description of the Component

Component ID
TCMH1390
Latin Name
Poncirus trifoliata
English Name
NA
Chinese Pinyin Name
Lv Yi Zhi Shi
中文名
绿衣枳实
TCM Properties
TCM Meridians
Therapeutic Class English
Therapeutic Class Chinese
Functions
Toxicity
NA
Geo-authentic habitats (道地产区)
NA
Reference
Chinese Pharmacopoeia (2015)
Barcode ID
Barcode Source

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name
TCMF5609 Wei De An Capsules 胃得安胶囊
TCMF5616 Wei De An Tablets 胃得安片

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT1 EHMT2 Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 Transferase Q96KQ7
TCMT101 PTPN1 Protein-tyrosine phosphatase 1B Hydrolase P18031
TCMT125 GBA Beta-glucocerebrosidase Hydrolase P04062
TCMT131 ACHE Acetylcholinesterase Hydrolase P22303
TCMT133 CA1 Carbonic anhydrase I Lyase P00915
TCMT134 CA2 Carbonic anhydrase II Lyase P00918
TCMT136 CA12 Carbonic anhydrase XII Lyase O43570
TCMT137 CA9 Carbonic anhydrase IX Lyase Q16790
TCMT138 CA7 Carbonic anhydrase VII Lyase P43166
TCMT162 UGT1A1 UDP-glucuronosyltransferase 1-1 Transferase P22309
TCMT2 MAPT Microtubule-associated protein tau Unclassified P10636
TCMT207 BACE1 Beta-secretase 1 Protease P56817
TCMT225 CA13 Carbonic anhydrase XIII Lyase Q8N1Q1
TCMT232 ABCB1 P-glycoprotein 1 Transporter P08183
TCMT265 GSK3B Glycogen synthase kinase-3 beta Kinase P49841
TCMT273 NR1H4 Bile acid receptor FXR Nuclear receptor Q96RI1
TCMT276 SLCO2B1 Solute carrier organic anion transporter family member 2B1 Transporter O94956
TCMT277 SLCO1B3 Solute carrier organic anion transporter family member 1B3 Transporter Q9NPD5
TCMT278 SLCO1B1 Solute carrier organic anion transporter family member 1B1 Transporter Q9Y6L6
TCMT3 ALOX15 Arachidonate 15-lipoxygenase Oxidoreductase P16050
TCMT31 CYP2C19 Cytochrome P450 2C19 Oxidoreductase P33261
TCMT33 CYP3A4 Cytochrome P450 3A4 Oxidoreductase P08684
TCMT34 CYP2D6 Cytochrome P450 2D6 Oxidoreductase P10635
TCMT599 UBE2N Ubiquitin-conjugating enzyme E2 N Transferase P61088
TCMT8 KDM4E Lysine-specific demethylase 4D-like Oxidoreductase B2RXH2
TCMT80 MAPK1 MAP kinase ERK2 Kinase P28482


Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1109 Reverse transcriptase
TCMT1112 Quinolone resistance protein norA
TCMT1255 Human immunodeficiency virus 1
TCMT1318 Human T-lymphotropic virus 1
TCMT1346 Helicobacter pylori
TCMT1438 Plasmodium falciparum
TCMT1439 Mycobacterium smegmatis
TCMT1454 Bacillus subtilis
TCMT1455 Mycobacterium tuberculosis H37Rv

Ingredient Structrues

Ingredient ID: TCMC749
Formula: C19H22O3

Ingredient ID: TCMC2663
Formula: C20H22O4

Ingredient ID: TCMC2242
Formula: C15H14O4

Ingredient ID: TCMC2241
Formula: C11H6O4

Ingredient ID: TCMC2086
Formula: C14H13NO4

Ingredient ID: TCMC2065
Formula: C14H12O3

Ingredient ID: TCMC1927
Formula: C18H14O4

Ingredient ID: TCMC1735
Formula: C27H32O14

Ingredient ID: TCMC1491
Formula: C26H30O8

Properties

Ingredient ID Formulae Name MW AlogP MlogP XlogP # HBA # HBD PSA # Rotatable Bond # Ring # Heacy Atom Lipinski RO5 Violation
TCMC749 C19H22O3 Auraptene 298.16 2.9159 3.22 5.074 1 0 35.53 9 2 22 1
TCMC1491 C26H30O8 Limonin 470.19 -0.4484 3.44 1.644 7 0 104.57 5 7 34 0
TCMC1735 C27H32O14 Naringin 580.18 -4.8082 2.89 -1.045 10 8 225.06 15 5 41 1
TCMC1927 C18H14O4 Pongamol 294.09 -0.6717 3 4.427 2 1 59.67 6 3 22 0
TCMC2065 C14H12O3 Sesalin 228.08 1.1778 2.67 2.932 1 0 35.53 2 3 17 0
TCMC2086 C14H13NO4 Skimmianine 259.08 -0.3095 2.45 1.624 1 0 53.72 6 3 19 0
TCMC2241 C11H6O4 Xanthotoxol 202.03 -0.3444 2.23 1.171 1 1 59.67 1 3 15 0
TCMC2242 C15H14O4 Xanthoxyletin 258.09 1.126 2.67 2.488 1 0 44.76 4 3 19 0
TCMC2663 C20H22O4 Dentatin 326.15 2.7477 3.22 4.288 1 0 44.76 8 3 24 0

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1. General Information of the Component  
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3. Putative Targets  
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5. Ingredient Data & Chemical Structure Information (Properties, InChI, InChIkey, SMILES, etc.)