TCM Prescription: Si Fang Wei Capsules



Prescription Description
Prescription IDTCMFx5797
Pinyin NameSi Fang Wei Jiao Nang
Chinese Name四方胃胶囊
English NameSi Fang Wei Capsules
Function Description胃脘痛
IndicationsStomach ache disorder
Disease ICD-11 Category SA51 [Stomach ache disorder (TM1), 胃脘痛 (TM1) ];
Human Tissues Associated with IndicationIntestine, Stomach
ReferenceCFDA
Reference Book/linkhttp://samr.cfda.gov.cn/WS01/CL0001/
Prescription Components
Component ID Latin Name Chinese Name Component Quantity Barcode
TCMH789 Lonicera japonica 海螵蛸 TCMH789 ITSAI3881-14
TCMH972 Coptis chinensis 黄连 TCMH972 ITSAO4469-14
TCMH2596 Fritillaria verticillata 浙贝母 TCMH2596
TCMH284 Melia toosendan 川楝子 TCMH284 KY197925
TCMH1219 Semen armeniacae amarum 苦杏仁 TCMH1219
TCMH1952 NA 柿霜 TCMH1952
TCMH2216 Evodia rutaecarpa 吴茱萸 TCMH2216
TCMH249 Aquilaria agallocha 沉香 TCMH249 KU879012
TCMH2376 Corydalis yanhusuo 延胡索 TCMH2376
Reference: CFDA

Targeted Human Proteins by the Ingredients of Prescription

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT112 ADORA3 Adenosine A3 receptor GPCR P0DMS8
TCMT131 ACHE Acetylcholinesterase Hydrolase P22303
TCMT160 HTR7 Serotonin 7 (5-HT7) receptor GPCR P34969
TCMT2 MAPT Microtubule-associated protein tau Unclassified P10636
TCMT223 AKR1B1 Aldose reductase Oxidoreductase P15121
TCMT27 DRD1 Dopamine D1 receptor GPCR P21728
TCMT296 ADORA1 Adenosine A1 receptor GPCR P30542
TCMT313 HTR2B Serotonin 2b (5-HT2b) receptor GPCR P41595
TCMT314 HTR2C Serotonin 2c (5-HT2c) receptor GPCR P28335
TCMT315 HTR6 Serotonin 6 (5-HT6) receptor GPCR P50406
TCMT316 MTNR1A Melatonin receptor 1A GPCR P48039
TCMT317 MTNR1B Melatonin receptor 1B GPCR P49286
TCMT33 CYP3A4 Cytochrome P450 3A4 Oxidoreductase P08684
TCMT34 CYP2D6 Cytochrome P450 2D6 Oxidoreductase P10635
TCMT36 HTR1A Serotonin 1a (5-HT1a) receptor GPCR P08908
TCMT37 HTR2A Serotonin 2a (5-HT2a) receptor GPCR P28223
TCMT38 DRD2 Dopamine D2 receptor GPCR P14416
TCMT46 F3 Coagulation factor III Unclassified P13726
TCMT597 SLC28A3 Solute carrier family 28 member 3 Transporter Q9HAS3
TCMT609 CTSL Cathepsin L Unclassified P07711
TCMT615 SENP8 Sentrin-specific protease 8 Protease Q96LD8
TCMT616 SENP7 Sentrin-specific protease 7 Protease Q9BQF6
TCMT643 ADRA1A Alpha-1a adrenergic receptor GPCR P35348
TCMT646 HTR5A Serotonin 5a (5-HT5a) receptor GPCR P47898
TCMT651 DRD3 Dopamine D3 receptor GPCR P35462
TCMT709 SLC28A2 Sodium/nucleoside cotransporter 2 Transporter O43868
TCMT710 SLC28A1 Sodium/nucleoside cotransporter 1 Transporter O00337
TCMT853 SIGMAR1 Sigma opioid receptor Unclassified Q99720


Targeted Pathogenic Microbes by the Ingredients of Prescription

Target ID Target Name
TCMT1214 Enterococcus faecium
TCMT1218 Staphylococcus aureus
TCMT1223 Staphylococcus epidermidis
TCMT1226 Klebsiella pneumoniae
TCMT1230 Human herpesvirus 5
TCMT1232 Pseudomonas aeruginosa
TCMT1236 Mycobacterium bovis
TCMT1246 Escherichia coli
TCMT1251 Candida albicans
TCMT1253 Penicillium chrysogenum
TCMT1255 Human immunodeficiency virus 1
TCMT1289 Shigella dysenteriae
TCMT1305 Salmonella enteritidis
TCMT1310 Enterococcus hirae
TCMT1318 Human T-lymphotropic virus 1
TCMT1346 Helicobacter pylori
TCMT1353 Plasmodium yoelii
TCMT1355 Rhodococcus equi
TCMT1382 Plasmodium falciparum (isolate K1 / Thailand)
TCMT1385 Candida shehatae
TCMT1438 Plasmodium falciparum
TCMT1439 Mycobacterium smegmatis
TCMT1442 Leishmania donovani
TCMT1454 Bacillus subtilis
TCMT1458 Filobasidiella neoformans
TCMT1460 Mycobacterium intracellulare
TCMT1462 Streptococcus mutans
TCMT1463 Mycobacterium tuberculosis
TCMT1464 Hepatitis B virus
TCMT1465 Entamoeba histolytica

Gene Ontology Associated to Targeted Human Proteins

GO Term GO Name Enriched Genes Log10 Adjusted P-value


KEGG Pathways Associated to Targeted Human Proteins

KEGG Pathway ID Enriched Genes Log10 Adjusted P-value


Target Exprsssion in Healthy Human Tissues (protein & mRNA level)

Protein expression data was from the "Human Proteome Map" dataset
mRNA expression data was from the "GTEx" dataset



Average Target Expression (Fold Change) in Multiple Disease Conditions

Fold Change with Corresponding Normal Samples
Click each cell within the heatmap to access gene expression of individual patient samples
Data Section
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1. General Information of Prescription  
2. Putative Targets  
3. Activity & References for Filtering Putative Targets  
4. GO & Pathway