Component: Oldenlandia diffusa 白花蛇舌草


Description of the Component

Component ID
TCMH71
Latin Name
Oldenlandia diffusa
English Name
Spreading hedyitis
Chinese Pinyin Name
Bai Hua She She Cao
中文名
白花蛇舌草
TCM Properties
Cold,Sweet,Slightly Bitter
TCM Meridians
Large Intestine,Stomach,Small Intestine
Therapeutic Class English
Antitumor
Therapeutic Class Chinese
抗肿瘤
Functions
eliminate heat and toxic material, promote blood circulation and remove blood stasis, clear dampness-heat
Toxicity
NA
Geo-authentic habitats (道地产区)
Fujian Province
Reference
Chinese Pharmacopoeia (2015)
Barcode ID
ITSAI3173-14
Barcode Source
BOLDSYSTEMS

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name
TCMF2168 Anti-Origin Decoction
TCMFx2997 Bai Hua She She Cao Zhu She Oral Liquid 白花蛇舌草注射液
TCMFx7145 Bai Shi Qing Re Granules 白石清热颗粒
TCMFx3615 Bi Yan Ling Tablets 鼻咽灵片
TCMFx1169 Bi Yan Ling Tablet 鼻咽灵片
TCMF2450 Breast Pit Drink
TCMFx2008 Clearing and Urine Promoting Combination Recipe 清淋合剂
TCMFx7067 Fei Li Ke Capsules 肺力咳胶囊
TCMFx2072 Five Herb Nephritis Decoction 五草汤
TCMFx3526 Fu Fang Gua Zi Jin Granules 复方瓜子金颗粒
TCMFx769 Fu Fang Gua Zi Jin Granules 复方瓜子金颗粒
TCMFx3702 Fu Fang Liu Ju Tablets 复方柳菊片
TCMF7239 Fu Ke Zhi Yang Capsules 妇科止痒胶囊
TCMFx3567 Gan Fu Kang Pills 肝复康丸
TCMF2545 Hepatitis B Removing Decoction
TCMFx4535 Hou Shu Ning Tablets 喉舒宁片
TCMFx4795 Hua Hong Granules 花红颗粒
TCMFx4802 Hua Hong Tablets 花红片
TCMFx582 Hua Hong Capsule 花红胶囊
TCMFx583 Hua Hong Granules 花红颗粒
TCMFx581 Hua Hong Tablet 花红片
TCMFx2167 Huang Qi Kidney Benefiting Decoction 黄芪益肾汤
TCMF714 Jin Pu Capsule 金蒲胶囊
TCMFx4033 Kang Ai Ping Pills 抗癌平丸
TCMF52 Kang Gu Sui Yan Tablets 抗骨髄炎片
TCMF4098 Kang Gu Sui Yan Tablets 抗骨髓炎片
TCMFx7043 Ke Ping Capsules 咳平胶囊
TCMF2264 Liver Soothing Decoction 疏肝活血汤
TCMF1179 Long Qing Tablet 癃清片
TCMFx4862 Luo Fu Shan Bai Cao You 罗浮山百草油
TCMF599 Nan Kang Tablet 男康片
TCMF4653 Nan Kang Tablets 男康片
TCMF5045 Qian Lie Hui Chun Capsules 前列回春胶囊
TCMFx5237 San Jie Zhi Tong Ointment 散结止痛膏
TCMF5512 Shen Shu Infusion 肾舒冲剂
TCMFx699 Shen Yan Kang Fu Tablet 肾炎康复片
TCMF423 Shuang Hu Qing Gan Granules 双虎清肝颗粒
TCMF2347 Tumor Desovling Decoction
TCMF6053 Xiao He Tablets 消核片
TCMFx6683 Yan Ning Infusion 炎宁冲剂
TCMFx98 Yan Ning Syrup 炎宁糖浆
TCMF835 Yang Zheng Xiao Ji Capsule 养正消积胶囊
TCMF1017 Yi Fei Qing Hua Ointment 益肺清化膏
TCMF6408 Yi Gan Ning Granules 乙肝宁颗粒
TCMF179 Yi Gan Ning Granules 乙肝宁颗粒
TCMF6825 Yin Lian Qing Gan Recipe 茵莲清肝合剂
TCMF730 Yin Qi Gan Fu Granules 茵芪肝复颗粒
TCMF2284 YJ Tiger and Snake Decoction
TCMFx6685 Yun Nan She Yao 云南蛇药

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT1 EHMT2 Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 Transferase Q96KQ7
TCMT101 PTPN1 Protein-tyrosine phosphatase 1B Hydrolase P18031
TCMT102 ACP1 Low molecular weight phosphotyrosine protein phosphatase Hydrolase P24666
TCMT103 PTPRF Receptor-type tyrosine-protein phosphatase F (LAR) Hydrolase P10586
TCMT11 HIF1A Hypoxia-inducible factor 1 alpha Transcription factor Q16665
TCMT112 ADORA3 Adenosine A3 receptor GPCR P0DMS8
TCMT125 GBA Beta-glucocerebrosidase Hydrolase P04062
TCMT13 APEX1 DNA-(apurinic or apyrimidinic site) lyase Lyase P27695
TCMT130 ALOX5 Arachidonate 5-lipoxygenase Oxidoreductase P09917
TCMT131 ACHE Acetylcholinesterase Hydrolase P22303
TCMT132 BCHE Butyrylcholinesterase Hydrolase P06276
TCMT133 CA1 Carbonic anhydrase I Lyase P00915
TCMT134 CA2 Carbonic anhydrase II Lyase P00918
TCMT135 CA14 Carbonic anhydrase XIV Lyase Q9ULX7
TCMT136 CA12 Carbonic anhydrase XII Lyase O43570
TCMT137 CA9 Carbonic anhydrase IX Lyase Q16790
TCMT138 CA7 Carbonic anhydrase VII Lyase P43166
TCMT139 CA6 Carbonic anhydrase VI Lyase P23280
TCMT140 CA5B Carbonic anhydrase VB Lyase Q9Y2D0
TCMT141 CA5A Carbonic anhydrase VA Lyase P35218
TCMT142 CA4 Carbonic anhydrase IV Lyase P22748
TCMT143 CA3 Carbonic anhydrase III Lyase P07451
TCMT150 RORC Nuclear receptor ROR-gamma Nuclear receptor P51449
TCMT151 PRKCA Protein kinase C alpha Kinase P17252
TCMT156 CYP19A1 Cytochrome P450 19A1 Oxidoreductase P11511
TCMT158 EPHX2 Epoxide hydratase Lyase P34913
TCMT159 TYR Tyrosinase Oxidoreductase P14679
TCMT160 HTR7 Serotonin 7 (5-HT7) receptor GPCR P34969
TCMT161 HCAR2 Hydroxycarboxylic acid receptor 2 GPCR Q8TDS4
TCMT162 UGT1A1 UDP-glucuronosyltransferase 1-1 Transferase P22309
TCMT166 AKR1C2 Aldo-keto reductase family 1 member C2 Oxidoreductase P52895
TCMT167 AKR1C3 Aldo-keto-reductase family 1 member C3 Oxidoreductase P42330
TCMT168 AKR1C4 Aldo-keto reductase family 1 member C4 Oxidoreductase P17516
TCMT17 POLB DNA polymerase beta Transferase P06746
TCMT171 PTPN6 Protein-tyrosine phosphatase 1C Hydrolase P29350
TCMT174 HSD11B1 11-beta-hydroxysteroid dehydrogenase 1 Oxidoreductase P28845
TCMT18 GAA Lysosomal alpha-glucosidase Hydrolase P10253
TCMT190 PTPN2 T-cell protein-tyrosine phosphatase Hydrolase P17706
TCMT195 MAP2K1 Dual specificity mitogen-activated protein kinase kinase 1 Kinase Q02750
TCMT2 MAPT Microtubule-associated protein tau Unclassified P10636
TCMT206 CYP2A6 Cytochrome P450 2A6 Oxidoreductase P11509
TCMT207 BACE1 Beta-secretase 1 Protease P56817
TCMT212 SRC Tyrosine-protein kinase SRC Kinase P12931
TCMT214 MGLL Monoglyceride lipase Unclassified Q99685
TCMT215 CYP1A1 Cytochrome P450 1A1 Oxidoreductase P04798
TCMT217 CYP2C8 Cytochrome P450 2C8 Oxidoreductase P10632
TCMT219 CYP1A2 Cytochrome P450 1A2 Oxidoreductase P05177
TCMT220 CYP2J2 Cytochrome P450 2J2 Oxidoreductase P51589
TCMT223 AKR1B1 Aldose reductase Oxidoreductase P15121
TCMT233 PTPN11 Protein-tyrosine phosphatase 2C Hydrolase Q06124
TCMT236 ESR2 Estrogen receptor beta Nuclear receptor Q92731
TCMT239 PIM1 Serine/threonine-protein kinase PIM1 Kinase P11309
TCMT240 AMY1A Salivary alpha-amylase Unclassified P04745
TCMT249 CDK6 Cyclin-dependent kinase 6 Kinase Q00534
TCMT257 CYP1B1 Cytochrome P450 1B1 Oxidoreductase Q16678
TCMT260 FLT3 Tyrosine-protein kinase receptor FLT3 Kinase P36888
TCMT261 DAPK1 Death-associated protein kinase 1 Kinase P53355
TCMT265 GSK3B Glycogen synthase kinase-3 beta Kinase P49841
TCMT27 DRD1 Dopamine D1 receptor GPCR P21728
TCMT273 NR1H4 Bile acid receptor FXR Nuclear receptor Q96RI1
TCMT276 SLCO2B1 Solute carrier organic anion transporter family member 2B1 Transporter O94956
TCMT277 SLCO1B3 Solute carrier organic anion transporter family member 1B3 Transporter Q9NPD5
TCMT278 SLCO1B1 Solute carrier organic anion transporter family member 1B1 Transporter Q9Y6L6
TCMT280 AKR1B10 Aldo-keto reductase family 1 member B10 Oxidoreductase O60218
TCMT281 DPP4 Dipeptidyl peptidase IV Unclassified P27487
TCMT297 FABP4 Fatty acid binding protein adipocyte Unclassified P15090
TCMT298 FABP3 Fatty acid binding protein muscle Hydrolase P05413
TCMT3 ALOX15 Arachidonate 15-lipoxygenase Oxidoreductase P16050
TCMT30 PTGS2 Cyclooxygenase-2 Oxidoreductase P35354
TCMT306 MMP2 Matrix metalloproteinase-2 Hydrolase P08253
TCMT31 CYP2C19 Cytochrome P450 2C19 Oxidoreductase P33261
TCMT320 MMP3 Matrix metalloproteinase 3 Hydrolase P08254
TCMT321 MMP9 Matrix metalloproteinase 9 Hydrolase P14780
TCMT322 MMP13 Matrix metalloproteinase 13 Hydrolase P45452
TCMT327 TRPV1 Vanilloid receptor Ion channel Q8NER1
TCMT33 CYP3A4 Cytochrome P450 3A4 Oxidoreductase P08684
TCMT331 PLG Plasminogen Unclassified P00747
TCMT34 CYP2D6 Cytochrome P450 2D6 Oxidoreductase P10635
TCMT36 HTR1A Serotonin 1a (5-HT1a) receptor GPCR P08908
TCMT369 IGF1R Insulin-like growth factor I receptor Kinase P08069
TCMT370 KDR Vascular endothelial growth factor receptor 2 Kinase P35968
TCMT374 AURKB Serine/threonine-protein kinase Aurora-B Kinase Q96GD4
TCMT388 AXL Tyrosine-protein kinase receptor UFO Kinase P30530
TCMT39 PDE5A Phosphodiesterase 5A Hydrolase O76074
TCMT401 MET Hepatocyte growth factor receptor Kinase P08581
TCMT402 ALK ALK tyrosine kinase receptor Kinase Q9UM73
TCMT41 IDH1 Isocitrate dehydrogenase [NADP] cytoplasmic Oxidoreductase O75874
TCMT42 KMT2A Histone-lysine N-methyltransferase MLL Transferase Q03164
TCMT422 CAMK2B CaM kinase II beta Kinase Q13554
TCMT423 EGFR Epidermal growth factor receptor erbB1 Kinase P00533
TCMT436 NUAK1 NUAK family SNF1-like kinase 1 Kinase O60285
TCMT44 GLO1 Glyoxalase I Lyase Q04760
TCMT441 PTK2 Focal adhesion kinase 1 Kinase Q05397
TCMT445 NEK2 Serine/threonine-protein kinase NEK2 Kinase P51955
TCMT45 APP Beta amyloid A4 protein Unclassified P05067
TCMT460 MAPKAPK2 MAP kinase-activated protein kinase 2 Kinase P49137
TCMT462 NEK6 Serine/threonine-protein kinase NEK6 Kinase Q9HC98
TCMT479 AKT1 Serine/threonine-protein kinase AKT Kinase P31749
TCMT484 PLK1 Serine/threonine-protein kinase PLK1 Kinase P53350
TCMT507 MAPK14 MAP kinase p38 alpha Kinase Q16539
TCMT508 SYK Tyrosine-protein kinase SYK Kinase P43405
TCMT558 TOP2A DNA topoisomerase II alpha Isomerase P11388
TCMT563 CDC25B Dual specificity phosphatase Cdc25B Hydrolase P30305
TCMT566 NOS2 Nitric oxide synthase, inducible Oxidoreductase P35228
TCMT592 XDH Xanthine dehydrogenase Oxidoreductase P47989
TCMT598 TOP1 DNA topoisomerase I Isomerase P11387
TCMT6 NFKB1 Nuclear factor NF-kappa-B p105 subunit Transcription factor P19838
TCMT601 F2 Thrombin Unclassified P00734
TCMT629 ABCC1 Multidrug resistance-associated protein 1 Transporter P33527
TCMT63 PPARA Peroxisome proliferator-activated receptor alpha Nuclear receptor Q07869
TCMT64 PPARD Peroxisome proliferator-activated receptor delta Nuclear receptor Q03181
TCMT640 CTSD Cathepsin D Unclassified P07339
TCMT65 HSD17B1 Estradiol 17-beta-dehydrogenase 1 Oxidoreductase P14061
TCMT66 HSD17B2 Estradiol 17-beta-dehydrogenase 2 Oxidoreductase P37059
TCMT67 PPARG Peroxisome proliferator-activated receptor gamma Nuclear receptor P37231
TCMT69 THRB Thyroid hormone receptor beta-1 Nuclear receptor P10828
TCMT734 MMP12 Matrix metalloproteinase 12 Hydrolase P39900
TCMT739 GPR35 G-protein coupled receptor 35 GPCR Q9HC97
TCMT740 PIK3CG PI3-kinase p110-gamma subunit Transferase P48736
TCMT747 ABCG2 ATP-binding cassette sub-family G member 2 Transporter Q9UNQ0
TCMT784 AVPR2 Vasopressin V2 receptor GPCR P30518
TCMT785 CXCR1 Interleukin-8 receptor A GPCR P25024
TCMT786 CCR4 C-C chemokine receptor type 4 GPCR P51679
TCMT791 PKN1 Protein kinase N1 Kinase Q16512
TCMT793 PYGL Liver glycogen phosphorylase Transferase P06737
TCMT8 KDM4E Lysine-specific demethylase 4D-like Oxidoreductase B2RXH2
TCMT80 MAPK1 MAP kinase ERK2 Kinase P28482
TCMT808 FABP5 Fatty acid binding protein epidermal Unclassified Q01469
TCMT809 FABP2 Fatty acid binding protein intestinal Unclassified P12104
TCMT81 ALOX12 Arachidonate 12-lipoxygenase Oxidoreductase P18054
TCMT810 TLR2 Toll-like receptor 2 Unclassified O60603
TCMT82 ESR1 Estrogen receptor alpha Nuclear receptor P03372
TCMT83 CD38 Lymphocyte differentiation antigen CD38 Unclassified P28907
TCMT87 CYP2C9 Cytochrome P450 2C9 Oxidoreductase P11712
TCMT95 MPG DNA-3-methyladenine glycosylase Hydrolase P29372


Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1090 Human immunodeficiency virus type 1 integrase
TCMT1092 Fatty acid synthase
TCMT1093 Enoyl-acyl-carrier protein reductase
TCMT1094 3-oxoacyl-acyl-carrier protein reductase
TCMT1099 Neuraminidase
TCMT1107 Protease
TCMT1109 Reverse transcriptase
TCMT1121 Sialidase
TCMT1136 Neuraminidase
TCMT1178 Actinomyces viscosus
TCMT1208 Escherichia coli K12
TCMT1209 Staphylococcus haemolyticus
TCMT1210 Streptococcus sobrinus
TCMT1211 Fusobacterium nucleatum
TCMT1212 Verticillium dahliae
TCMT1218 Staphylococcus aureus
TCMT1222 Plasmodium falciparum D6
TCMT1223 Staphylococcus epidermidis
TCMT1226 Klebsiella pneumoniae
TCMT1229 Enterococcus faecalis
TCMT1246 Escherichia coli
TCMT1248 Hepatitis C virus
TCMT1251 Candida albicans
TCMT1253 Penicillium chrysogenum
TCMT1255 Human immunodeficiency virus 1
TCMT1286 Bacillus cereus
TCMT1321 Staphylococcus hominis
TCMT1343 Staphylococcus simulans
TCMT1344 Staphylococcus sciuri
TCMT1346 Helicobacter pylori
TCMT1349 Helicobacter pylori SS1
TCMT1361 Neisseria meningitidis
TCMT1370 Prevotella melaninogenica
TCMT1382 Plasmodium falciparum (isolate K1 / Thailand)
TCMT1412 Salmonella typhimurium
TCMT1438 Plasmodium falciparum
TCMT1442 Leishmania donovani
TCMT1443 Leishmania amazonensis
TCMT1448 Enterobacter aerogenes
TCMT1454 Bacillus subtilis
TCMT1455 Mycobacterium tuberculosis H37Rv
TCMT1458 Filobasidiella neoformans
TCMT1462 Streptococcus mutans
TCMT1463 Mycobacterium tuberculosis
TCMT1465 Entamoeba histolytica

Ingredient Structrues

Ingredient ID: TCMC948
Formula: C9H8O3

Ingredient ID: TCMC671
Formula: C10H16

Ingredient ID: TCMC505
Formula: C8H8O

Ingredient ID: TCMC473
Formula: C10H16O

Ingredient ID: TCMC395
Formula: C9H16O

Ingredient ID: TCMC2671
Formula: C8H14O

Ingredient ID: TCMC2411
Formula: C30H48O3

Ingredient ID: TCMC2324
Formula: C10H16

Ingredient ID: TCMC2216
Formula: C30H48O3

Ingredient ID: TCMC2166
Formula: C10H14O

Ingredient ID: TCMC2031
Formula: C27H30O16

Ingredient ID: TCMC1982
Formula: C15H10O7

Ingredient ID: TCMC1830
Formula: C16H32O2

Ingredient ID: TCMC1786
Formula: C30H48O3

Ingredient ID: TCMC170
Formula: C10H14O

Ingredient ID: TCMC1611
Formula: C14H28O2

Ingredient ID: TCMC1315
Formula: C7H14O

Ingredient ID: TCMC1238
Formula: C10H18O

Ingredient ID: TCMC1173
Formula: C10H10O4

Properties

Ingredient ID Formulae Name MW AlogP MlogP XlogP # HBA # HBD PSA # Rotatable Bond # Ring # Heacy Atom Lipinski RO5 Violation
TCMC170 C10H14O (S)(+)Carvone 150.1 1.5954 2.45 1.756 1 0 17.07 3 1 11 0
TCMC395 C9H16O 2-Nonenal 140.12 -0.6764 2.34 3.557 1 0 17.07 7 0 10 0
TCMC473 C10H16O 4,7,7-Trimethylbicyclo[2.2.1]Heptan-3-One 152.12 0.9693 2.45 2.127 1 0 17.07 3 2 11 0
TCMC505 C8H8O 4-Methylbenzaldehyde 120.06 0.4496 2.23 3.403 1 0 17.07 2 1 9 0
TCMC671 C10H16 Alpha-Pinene 136.13 1.5162 2.56 4.177 0 0 0 3 1 10 0
TCMC948 C9H8O3 Coumaric Acid 164.05 -0.339 2.12 1.886 2 2 57.53 4 1 12 0
TCMC1173 C10H10O4 Ferulic Acid 194.06 -0.3908 2.12 1.231 2 2 66.76 6 1 14 0
TCMC1238 C10H18O Geraniol 154.14 2.3397 2.45 2.524 1 1 20.23 8 0 11 0
TCMC1315 C7H14O Heptanal 114.1 -1.2583 2.12 2.863 1 0 17.07 6 0 8 0
TCMC1611 C14H28O2 Myristic Acid 228.21 -3.3217 2.78 6.432 2 1 37.3 14 0 16 2
TCMC1786 C30H48O3 Oleanolic_Acid 456.36 2.1298 4.43 9.052 3 2 57.53 10 5 33 1
TCMC1830 C16H32O2 Palmitic Acid 256.24 -3.8977 3 7.57 2 1 37.3 16 0 18 2
TCMC1982 C15H10O7 Quercetin 302.04 -2.8012 2.34 1.381 2 5 127.45 6 3 22 0
TCMC2031 C27H30O16 Rutin 610.15 -6.139 2.67 -1.188 11 10 265.52 17 5 43 2
TCMC2166 C10H14O Thymol 150.1 0.7546 2.45 3.556 0 1 20.23 5 1 11 0
TCMC2216 C30H48O3 Ursolic Acid 456.36 1.4838 4.43 8.954 3 2 57.53 10 5 33 1
TCMC2324 C10H16 Limonene 136.13 2.1424 2.56 3.729 0 0 0 3 1 10 0
TCMC2411 C30H48O3 Epi-Oleanolic Acid 456.36 2.1298 4.43 9.052 3 2 57.53 10 5 33 1
TCMC2671 C8H14O (E)-2-Octenal 126.1 -0.3884 2.23 2.988 1 0 17.07 6 0 9 0

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1. General Information of the Component  
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3. Putative Targets  
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