Natural Product Target: Cruzipain

Target ID:   NPT791
Target Name:   Cruzipain
Target Type:   Individual Protein
Organism of Target:   Trypanosoma cruzi
Target External ID:   Uniprot_ID:[ P25779]

  Biological Activities of Natural Products against the Target

Natural Product ID Natural Product Name # Activity Records
NPC68441 Gossypol 6
NPC476440 Tpck 6
NPC323937 Famotidine 4
NPC20791 Quercetin 4
NPC116961 Loratadine 4
NPC169749 Myricetin 4
NPC469949 Clofazimine 4
NPC76336 Scopoletin 4
NPC149571 Raloxifene 4
NPC179787 Harman 4
NPC173555 Digoxin 3
NPC123814 Dihydrospingosine 3
NPC72260 Digitoxin 3
NPC125039 Silibinin 3
NPC316910 Celecoxib 3
NPC208553 Paclitaxel 3
NPC55412 Retinol 3
NPC226066 Retinyl Acetate 3
NPC323477 (5S,6Z,8E,10E,12R,14Z)-5,12-Dihydroxyicosa-6,8,10,14-Tetraenedioic Acid 2
NPC66191 Dactinomycin 2
NPC158179 Icosa-5,8,11,14-Tetraynoic Acid 2
NPC279121 Luteolin 2
NPC158388 Ionomycin 2
NPC67250 Naphthalene-1,4,5-Triol 2
NPC250999 Zinc;1-Oxidopyridine-2-Thione 2
NPC284475 Menatetrenone 2
NPC85233 Nobiletin 2
NPC254698 Isatin 2
NPC51443 Fisetin 2
NPC289432 1,6-Dimethyl-1,2-Dihydronaphtho[1,2-G][1]Benzofuran-10,11-Dione 2
NPC308885 Zucapsaicin 2
NPC313449 Dequalinium 2
NPC257236 Rottlerin 2
NPC314496 Endrin 2
NPC206264 Esculin 2
NPC91495 Arachidonic Acid 2
NPC175013 Tricetin 2
NPC207428 Deoxyvasicinone 2
NPC470091 Stictic Acid 2
NPC233455 Enoxolone 2
NPC125416 Chlorhexidine 2
NPC294548 Linolenic Acid 2
NPC72980 Harmalol 2
NPC97577 Lovastatin 2
NPC177281 (10-Acetyloxy-8,8-Dimethyl-2-Oxo-9,10-Dihydropyrano[2,3-F]Chromen-9-Yl) 3-Methylbutanoate 2
NPC317177 Tretinoin 2
NPC21429 Rutaecarpine 2
NPC269877 Cholecalciferol 2
NPC178134 Ellagic Acid 2
NPC39426 Genistein 2
NPC272426 Sodium Lauryl Sulfate 2
NPC215584 Elliptecine 2
NPC56271 Gefitinib 2
NPC57565 Dalfampridine 2
NPC298796 Citropten 1
NPC188433 Macluraxanthone 1
NPC80089 Cholic Acid 1
NPC23155 1,3-Dihydroxypropan-2-Yl Hexadecanoate 1
NPC108288 Juglone 1
NPC245531 Chlorothalonil 1
NPC64872 (4As,6As,6Br,8R,10S,12Ar)-8,10-Dihydroxy-2,2,6A,6B,9,9,12A-Heptamethyl-1,3,4,5,6,6A,7,8,8A,10,11,12,13,14B-Tetradecahydropicene-4A-Carboxylic Acid 1
NPC278175 (Z)-1-[6-[(3-Acetyl-2,4,6-Trihydroxy-5-Methylphenyl)Methyl]-5,7-Dihydroxy-2,2-Dimethylchromen-8-Yl]-3-Phenylprop-2-En-1-One 1
NPC300059 Taurine 1
NPC190461 n.a. 1
NPC81896 2-Arachidonoylglycerol 1
NPC23508 Ethyl Acetate 1
NPC109083 Curcumin 1
NPC49422 (3E)-3-[(2E)-2-[1-[(E)-5,6-Dimethylhept-3-En-2-Yl]-7A-Methyl-2,3,3A,5,6,7-Hexahydro-1H-Inden-4-Ylidene]Ethylidene]-4-Methylidenecyclohexan-1-Ol 1
NPC247553 Umbelliferone 1
NPC67076 Prostaglandin A2 1
NPC160900 (1E,6E)-1,7-Bis(4-Hydroxy-3-Methoxyphenyl)Hepta-1,6-Diene-3,5-Dione 1
NPC282307 Pomiferin 1
NPC4638 Canthaxanthin 1
NPC301585 Myristic Acid 1
NPC84478 Harmaline 1
NPC325734 Arachidonoyl Glycine 1
NPC227396 Prostaglandin B1 1
NPC111201 2,6-Diacetyl-7,9-Dihydroxy-8,9B-Dimethyldibenzofuran-1,3-Dione 1
NPC50898 Apigenin 1
NPC18509 Hydrocortisone 1
NPC67917 Amphotericin B 1
NPC307006 2-Hydroxy-2-(4-Hydroxy-3-Methoxyphenyl)Acetic Acid 1
NPC192744 Betunolic Acid 1
NPC325871 1,2,9,10-Tetramethoxy-6-Methyl-5,6,6A,7-Tetrahydro-4H-Dibenzo[De,G]Quinoline 1
NPC227841 Hypericin 1
NPC115418 Dinoprostone 1
NPC26617 Thapsigargin 1
NPC163099 Agmatine 1
NPC287795 Bilirubin 1
NPC68354 Ergonovine 1
NPC307965 17-[(E)-5,6-Dimethylhept-3-En-2-Yl]-10,13-Dimethyl-2,3,4,9,11,12,14,15,16,17-Decahydro-1H-Cyclopenta[A]Phenanthren-3-Ol 1
NPC196449 Calcimycin 1
NPC87125 Rhamnetin 1
NPC325936 [(2R)-2-[(4Z,7Z,10Z,13Z,16Z,19Z)-Docosa-4,7,10,13,16,19-Hexaenoyl]Oxy-3-Hexadecoxypropyl] 2-(Trimethylazaniumyl)Ethyl Phosphate 1
NPC228785 Mangostin 1
NPC116775 Kaempferol 1
NPC254847 Emodin 1
NPC165549 Deguelin 1
NPC201276 Cholic Acid, Methyl Ester 1
NPC88735 Prostaglandin F1Alpha 1
NPC326645 Alitretinoin 1
NPC25581 3-(3,4-Dihydroxyphenyl)-2-[(E)-3-(3,4-Dihydroxyphenyl)Prop-2-Enoyl]Oxypropanoic Acid 1
NPC191835 Zearalanone 1
NPC255042 Geraniol 1
NPC291389 Harmol 1
NPC69101 Moronic Acid 1
NPC201731 Osajin 1
NPC90652 (5R,9R,10R,13S,14S,17S)-4,4,10,13,14-Pentamethyl-17-[(2S,4R,5S)-4,5,6-Trihydroxy-6-Methylheptan-2-Yl]-1,2,5,6,9,11,12,15,16,17-Decahydrocyclopenta[A]Phenanthren-3-One 1
NPC326651 (3R)-3-Hexadecanoyloxy-4-(Trimethylazaniumyl)Butanoate 1
NPC25848 (1S,2R,4As,6As,6Br,8R,9R,10R,11R,12Ar)-8,10,11-Trihydroxy-9-(Hydroxymethyl)-1,2,6A,6B,9,12A-Hexamethyl-2,3,4,5,6,6A,7,8,8A,10,11,12,13,14B-Tetradecahydro-1H-Picene-4A-Carboxylic Acid 1
NPC122504 Euphorbiasteroid 1
NPC476615 (6S,6aR,7S,12aR)-7-[(E)-2-(4-hydroxyphenyl)ethenyl]-1,8-dimethoxy-6-phenyl-6,6a,7,12a-tetrahydrochromeno[3,2-c]chromene-3,10-diol 1
NPC291548 n.a. 1
NPC70201 4-Aminophenol 1
NPC202666 Glycyrrhizin 1
NPC90875 Oxopurpureine 1
NPC329003 Oleoylethanolamide 1
NPC232727 Harmine 1
NPC476616 (6S,6aR,7S,12aR)-1,8-dimethoxy-7-[(E)-2-(4-methoxyphenyl)ethenyl]-6-phenyl-6,6a,7,12a-tetrahydrochromeno[3,2-c]chromene-3,10-diol 1
NPC266597 Pratol 1
NPC174754 3-Hydroxy-4-Methoxybenzaldehyde Thiosemicarbazone 1
NPC292265 Ciprofloxacin 1
NPC315216 7,12-Dimethylbenzo[A]Anthracene 1
NPC329416 Isotretinoin 1
NPC233267 Diffractaic Acid 1
NPC476617 (6S,6aR,7S,12aR)-1,8-dimethoxy-6-phenyl-7-[(E)-2-phenylethenyl]-6,6a,7,12a-tetrahydrochromeno[3,2-c]chromene-3,10-diol 1
NPC266689 Xanthoangelol 1
NPC33986 Columbianetin 1
NPC72722 2-Dodecyl-3-Methylbutanedioic Acid 1
NPC316756 Pantoprazole 1
NPC97260 Actein 1
NPC477530 Mundulone 1
NPC267885 Acetyltryptophan 1
NPC176127 n.a. 1
NPC208193 Deslanoside 1
NPC234053 Griseofulvin 1
NPC126935 Galgravin 1
NPC55068 Sphingosine 1
NPC268534 Acridone 1
NPC296377 Nodakenin 1
NPC73492 Cepharanthine 1
NPC100586 (3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-4,4,8,10,14-Pentamethyl-17-[(2S)-2,6,6-Trimethyloxan-2-Yl]-2,3,5,6,7,9,11,12,13,15,16,17-Dodecahydro-1H-Cyclopenta[A]Phenanthrene-3,6,12-Triol 1
NPC475524 Cucurbitacin B 1
NPC238629 Purpurin 1
NPC13504 1,10-Dimethoxy-6-Methyl-5,6,6A,7-Tetrahydro-4H-Dibenzo[De,G]Quinoline-2,9-Diol 1
NPC55149 Columbianadin 1
NPC298093 Rotenone 1
NPC74458 Benzylacetone 1
NPC101307 (1R,2R,4As,8As)-1-[(3S)-3-Hydroxy-3-Methylpent-4-Enyl]-2,5,5,8A-Tetramethyl-3,4,4A,6,7,8-Hexahydro-1H-Naphthalen-2-Ol 1
NPC33144 Zearalenone 1
NPC238861 1,6,6-Trimethyl-2,7,8,9-Tetrahydro-1H-Naphtho[1,2-G][1]Benzofuran-10,11-Dione 1
NPC129909 Camptothecin 1
NPC179092 Gingkolic Acid 1
NPC321568 (2Z,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-Trimethylcyclohexen-1-Yl)Nona-2,4,6,8-Tetraenal 1
NPC102008 Atorvastatin 1
NPC471614 Ketoconazole 1
NPC239312 Baicalein 1
NPC55422 n.a. 1
NPC273758 Dibenzoylmethane 1
NPC76879 1-[(3S,8R,9S,10R,13S,14S,17R)-3,17-Dihydroxy-10,13-Dimethyl-1,2,3,4,7,8,9,11,12,14,15,16-Dodecahydrocyclopenta[A]Phenanthren-17-Yl]Ethanone 1
NPC322319 (3R)-3-Tetradecanoyloxy-4-(Trimethylazaniumyl)Butanoate 1
NPC218530 Dihydrocapsaicin 1
NPC105648 Lecanoric Acid 1
NPC468984 Ampicillin 1
NPC27853 n.a. 1
NPC151214 Cumingianoside A 1
NPC31700 Staurosporine Aglycon 1
NPC183845 (S)-2-Aminoadipic Acid 1
NPC79618 N-Phenylnaphthalen-1-Amine 1
NPC322457 (Z)-7-[(1S,5E)-5-[(E)-Oct-2-Enylidene]-4-Oxocyclopent-2-En-1-Yl]Hept-5-Enoic Acid 1
NPC108191 n.a. 1
NPC245187 2,3-Dimethylphenol 1
NPC155444 Ergocryptine 1
NPC277021 4-Methylesculetin 1

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3. Compound Information: compound related data of all natural products that have available activity against this target;
4. Species Source: species sources that all natural products that have available activity against this target derived from.

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