Natural Product Target: Anthrax lethal factor

Target ID:   NPT150
Target Name:   Anthrax lethal factor
Target Type:   Individual Protein
Organism of Target:   Bacillus anthracis
Target External ID:   Uniprot_ID:[ P15917]

  Biological Activities of Natural Products against the Target

Natural Product ID Natural Product Name # Activity Records
NPC169749 Myricetin 3
NPC469308 Sb-203580 3
NPC226941 Colchicine 3
NPC108957 N-[(7R)-1,2,3,10-Tetramethoxy-9-Oxo-6,7-Dihydro-5H-Benzo[A]Heptalen-7-Yl]Acetamide 3
NPC200085 Naramycin B 2
NPC273330 D-Glutamate 2
NPC22130 Diphyllin 2
NPC473206 Diphenyleneiodonium 2
NPC273532 Quinolinic Acid 2
NPC39426 Genistein 2
NPC143168 Embelin 2
NPC278175 (Z)-1-[6-[(3-Acetyl-2,4,6-Trihydroxy-5-Methylphenyl)Methyl]-5,7-Dihydroxy-2,2-Dimethylchromen-8-Yl]-3-Phenylprop-2-En-1-One 2
NPC308885 Zucapsaicin 2
NPC253703 Cycloheximide 2
NPC149571 Raloxifene 2
NPC279121 Luteolin 2
NPC471603 Sb-202190 2
NPC239312 Baicalein 2
NPC76336 Scopoletin 2
NPC76682 n.a. 2
NPC319972 Acetohydroxamic Acid 2
NPC282294 Ethacrynic Acid 2
NPC473417 Trifluoperazine 2
NPC256849 Caffeine 2
NPC46451 Sanguinarium 2
NPC114325 Guaiacol 2
NPC129909 Camptothecin 2
NPC215584 Elliptecine 2
NPC314940 Oxyquinoline 2
NPC68441 Gossypol 1
NPC302159 2-Picolinic Acid 1
NPC169485 [(1S,5R)-8-Methyl-8-Azabicyclo[3.2.1]Octan-3-Yl] (2R)-3-Hydroxy-2-Phenylpropanoate 1
NPC63479 Pentachlorophenol 1
NPC94167 Riboflavin 1
NPC315921 Salicylamide 1
NPC119669 6,7-Dimethoxy-2-Methyl-3,4-Dihydroisoquinolin-1-One 1
NPC328920 Carbon Tetrachloride 1
NPC289484 Palmidrol 1
NPC142492 Cyclopentane 1
NPC231884 (S)-Verapamil 1
NPC70201 4-Aminophenol 1
NPC305912 Bis(2-Ethylhexyl) Phthalate 1
NPC65517 Hydroquinone 1
NPC95162 Fraxetin 1
NPC317177 Tretinoin 1
NPC200845 Ethyl (9E,12E,15E)-Octadeca-9,12,15-Trienoate 1
NPC120441 Prop-1-En-2-Ylbenzene 1
NPC329003 Oleoylethanolamide 1
NPC222061 4-Thiouracil 1
NPC290566 4-[(1R)-2-Amino-1-Hydroxyethyl]Phenol 1
NPC142599 N-[2-(3,4-Dihydroxyphenyl)Ethyl]Acetamide 1
NPC213914 Caulibugulone D 1
NPC233791 2,5-Dimethylfuran 1
NPC72980 Harmalol 1
NPC36108 Isoeugenol 1
NPC172937 Vitamin B2 1
NPC97870 Esatenolol 1
NPC202771 Noscapine 1
NPC277704 Toluene 1
NPC120671 (6R)-6-[(5R)-6-Methyl-7,8-Dihydro-5H-[1,3]Dioxolo[4,5-G]Isoquinolin-5-Yl]-6H-Furo[3,4-G][1,3]Benzodioxol-8-One 1
NPC329416 Isotretinoin 1
NPC223004 2,6-Dihydroxybenzoic Acid 1
NPC434 N-Phenylnaphthalen-2-Amine 1
NPC469330 1400W 1
NPC233835 Naphthalene-1,2-Diol 1
NPC73020 Hydrastine 1
NPC306843 Boldine 1
NPC173555 Digoxin 1
NPC252603 Theophylline 1
NPC100079 Chelerythrine 1
NPC317400 Tolbutamide 1
NPC204210 2,4-Dimethylphenol 1
NPC120719 4-Tert-Butylbenzene-1,2-Diol 1
NPC470090 Sp-600125 1
NPC225539 Furan 1
NPC32955 Acrylamide 1
NPC147000 Pseudoephedrine 1
NPC51146 Psoralen 1
NPC234822 n.a. 1
NPC74539 Bergapten 1
NPC176381 Neomycin 1
NPC100551 Salicylic Acid 1
NPC318935 Pyridine-2,3-Diol 1
NPC204932 Catechol 1
NPC278758 Dichloroacetic Acid 1
NPC123273 4-Nonylphenol 1
NPC33144 Zearalenone 1
NPC225710 Gallic Acid 1
NPC33229 Pyrrole-2-Carboxylic Acid 1
NPC7846 Sid489025 1
NPC237946 Podofilox 1
NPC6854 Olvanil 1
NPC309367 Thiram 1
NPC176858 Biphenyl-4-Amine 1
NPC253810 3-Hydroxypicolinic Acid 1
NPC102423 Indole-3-Carbinol 1
NPC319549 n.a. 1
NPC205421 Isocorydine 1
NPC123814 Dihydrospingosine 1
NPC226453 Arginine 1
NPC291389 Harmol 1
NPC156021 Lawsone 1
NPC75694 Mycophenolic Acid 1
NPC311219 Aspirin 1
NPC178134 Ellagic Acid 1
NPC254847 Emodin 1
NPC11433 L-Proline 1
NPC319933 2,4-Dibromo-1-(2,4-Dibromophenoxy)Benzene 1
NPC208553 Paclitaxel 1
NPC281943 3-Methylbutyl Acetate 1
NPC125039 Silibinin 1
NPC291548 n.a. 1
NPC156654 Protocatechuic Acid 1
NPC473432 Amsacrine 1
NPC241089 2,4-Dihydroxybenzoic Acid 1
NPC51695 4-[(2R)-2-[(1R,3R,5S)-3,5-Dimethyl-2-Oxocyclohexyl]-2-Hydroxyethyl]Piperidine-2,6-Dione 1
NPC242895 Phloretin 1
NPC312800 Gentisic Acid 1
NPC179787 Harman 1
NPC30009 4'-Demethyldeoxypodophyllotoxin 1
NPC208793 Aspartic Acid 1
NPC281986 Retinal 1
NPC125416 Chlorhexidine 1
NPC43945 Menadione 1
NPC227553 Salicyluric Acid 1
NPC33320 Methoxsalen 1
NPC18224 Adipic Acid 1
NPC292265 Ciprofloxacin 1
NPC158853 Maltol 1
NPC51957 Hydron;2,3,9,10-Tetramethoxy-6,8,13,13A-Tetrahydro-5H-Isoquinolino[2,1-B]Isoquinoline;Chloride 1
NPC245896 Pyrene 1
NPC7214 Conessine 1
NPC314278 4-Nitrobenzoic Acid 1
NPC181526 3-Amino-2-Hydroxybenzoic Acid 1
NPC255345 Fluoranthene 1
NPC109403 Daunorubicin 1
NPC40209 1-Tert-Butyl-2-Methoxy-4-Methyl-3,5-Dinitrobenzene 1
NPC208936 (2E,4E)-Deca-2,4-Dienal 1
NPC32373 Picropodophyllotoxin 1
NPC125549 1-Chloro-4-(4-Chlorophenyl)Sulfonylbenzene 1
NPC74357 Caulibugulone B 1
NPC24019 Oxoglaucine 1
NPC2741 3-Hydroxypyran-4-One 1
NPC159589 Chloramphenicol 1
NPC1075 (Z)-3-(3,4-Dihydroxyphenyl)Prop-2-Enoic Acid 1
NPC248573 Cis-Resveratrol 1
NPC78625 Ricinine 1
NPC314496 Endrin 1
NPC185768 Pentane-2,4-Dione 1
NPC255817 (2Z,4Z)-5-(1,3-Benzodioxol-5-Yl)-1-Piperidin-1-Ylpenta-2,4-Dien-1-One 1
NPC110126 Gramine 1
NPC321561 Methyldopa 1
NPC209560 Formononetin 1
NPC129889 (2S)-2-Hydroxy-2-(4-Hydroxy-3-Methoxyphenyl)Acetic Acid 1
NPC228343 Nordihydroguaiaretic Acid 1
NPC293799 Gs-39783 1
NPC18335 Adenine 1
NPC54654 n.a. 1
NPC248627 6-Methylpyrimidine-2,4-Diol 1
NPC79618 N-Phenylnaphthalen-1-Amine 1
NPC314598 Moroxydine 1
NPC187145 3-(1H-Benzimidazol-2-Yl)-7-(Diethylamino)Chromen-2-One 1
NPC113236 (Z)-Piplartine 1
NPC321568 (2Z,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-Trimethylcyclohexen-1-Yl)Nona-2,4,6,8-Tetraenal 1
NPC210642 [(5R,5Ar,8Ar,9R)-8-Oxo-9-(3,4,5-Trimethoxyphenyl)-5A,6,8A,9-Tetrahydro-5H-[2]Benzofuro[5,6-F][1,3]Benzodioxol-5-Yl] Acetate 1
NPC282307 Pomiferin 1
NPC13768 (R)-Pinocembrin 1
NPC228785 Mangostin 1
NPC294249 (1S)-7-Methoxy-1-Methyl-1,2,3,4-Tetrahydroisoquinolin-6-Ol 1
NPC160900 (1E,6E)-1,7-Bis(4-Hydroxy-3-Methoxyphenyl)Hepta-1,6-Diene-3,5-Dione 1
NPC57279 T-Zeatin 1
NPC83987 Pyridine 1
NPC36836 Nicardipine 1
NPC187868 5,7-Dihydroxy-4-Methylcoumarin 1
NPC260837 2,3-Dihydroxybenzoic Acid 1
NPC322644 Quinaldic Acid 1
NPC211421 Hydroxytoluic Acid 1
NPC32441 Naringenin 1
NPC46565 Hinokitiol 1
NPC228932 (2R)-2-Azaniumyl-3-Sulfosulfanylpropanoate 1
NPC296482 Berberine Chloride 1
NPC163099 Agmatine 1
NPC57565 Dalfampridine 1
NPC84478 Harmaline 1
NPC37496 Glabranin 1
NPC190334 4-Amino-1-[(2R,3R,4S,5S)-3,4-Dihydroxy-5-(Hydroxymethyl)Oxolan-2-Yl]Pyrimidin-2-One 1
NPC262768 Endosulfan 1
NPC114517 Beta-Alanine 1
NPC326645 Alitretinoin 1
NPC283908 Pimaric Acid 1
NPC137949 Esculetin 1
NPC229055 Caulibugulone C 1
NPC229084 (1Z,6Z)-1,7-Bis(4-Hydroxy-3-Methoxyphenyl)Hepta-1,6-Diene-3,5-Dione 1
NPC298093 Rotenone 1
NPC164697 (-)-Usnic Acid 1
NPC60553 1H-Quinolin-2-One 1
NPC85443 Dipicolinic Acid 1
NPC190461 n.a. 1
NPC263058 Neamine 1
NPC115281 Beta-Peltatin A 1
NPC326651 (3R)-3-Hexadecanoyloxy-4-(Trimethylazaniumyl)Butanoate 1
NPC217052 Cichoric Acid 1
NPC286641 Iodoform 1
NPC138113 Myrcene 1
NPC471614 Ketoconazole 1
NPC229242 Toluic Acid 1
NPC301585 Myristic Acid 1
NPC165549 Deguelin 1
NPC62765 Benzoic Acid 1
NPC85661 Aristolochic Acid 1
NPC314968 1-Methyl-1-Nitroso-3-[2,4,5-Trihydroxy-6-(Hydroxymethyl)Oxan-3-Yl]Urea 1
NPC191104 Bergamottin 1
NPC265782 E-Guggulsterone 1
NPC116366 Kojic Acid 1
NPC41717 Fusaric Acid 1
NPC218530 Dihydrocapsaicin 1
NPC286989 Dexfosfoserine 1
NPC141791 2-Phenylethyl (Z)-3-(3,4-Dihydroxyphenyl)Prop-2-Enoate 1
NPC49075 Berbamine 1
NPC230805 8-Hydroxy-2-Methyl-1H-Quinazolin-4-One 1
NPC301702 Aminosalicylic Acid 1
NPC168758 Spartioidine 1
NPC63284 n.a. 1
NPC88923 Reserpine 1
NPC315257 Spiramide 1
NPC194562 Transtorine 1
NPC272426 Sodium Lauryl Sulfate 1
NPC116775 Kaempferol 1
NPC328877 Phenothiazine 1
NPC219143 Serine 1
NPC287638 n.a. 1
NPC142330 Urea 1
NPC476440 Tpck 1
NPC231149 Daphnoretin 1

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4. Species Source: species sources that all natural products that have available activity against this target derived from.

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