Drug Information

Drug ID:  NPD2606
Drug Name:  Levorphanol
Molecular Formula:  C17H23NO
Canonical SMILES:  Oc1ccc2c(c1)[C@]13CCCC[C@H]3[C@@H](C2)N(CC1)C
Standard InCHI:  InChI=1S/C17H23NO/c1-18-9-8-17-7-3-2-4-14(17)16(18)10-12-5-6-13(19)11-15(12)17/h5-6,11,14,16,19H,2-4,7-10H2,1H3/t14-,16+,17+/m0/s1
Standard InCHIKey:  JAQUASYNZVUNQP-USXIJHARSA-N
Max Developmental Stage:  Approved
Max Developmental Stage Source:  TTD; ChEMBL; IUPHAR/BPS

  Structural Similarity Between NPASS Natural Products and NPD2606

Similarity level is defined by Tanimoto coefficient (Tc) between two molecules. Tc lies between [0, 1] where '1' indicates the highest similarity. What is Tanimoto coefficient
Tanimoto coefficient is calculated based on PubChem 881-bit substructure fingerprints.


  Similar Natural Products

High Similarity Level: Tc>=0.85; Intermediate Similarity Level: 0.7 <= Tc < 0.85; Remote Similarity Level: 0.65 <= Tc < 0.7

Similarity Level Similarity Score Natural Product ID
High Similarity 0.9918 NPC126859
High Similarity 0.9918 NPC259665
High Similarity 0.9918 NPC89769
High Similarity 0.9836 NPC124802
High Similarity 0.9754 NPC8305
High Similarity 0.9754 NPC268763
High Similarity 0.9754 NPC66177
High Similarity 0.9444 NPC149379
High Similarity 0.8923 NPC325568
Intermediate Similarity 0.8092 NPC307020
Intermediate Similarity 0.8071 NPC470925
Intermediate Similarity 0.8065 NPC322753
Intermediate Similarity 0.7984 NPC141782
Intermediate Similarity 0.7967 NPC11554
Intermediate Similarity 0.792 NPC176279
Intermediate Similarity 0.792 NPC260323
Intermediate Similarity 0.7874 NPC195922
Intermediate Similarity 0.7857 NPC250323
Intermediate Similarity 0.784 NPC13482
Intermediate Similarity 0.7763 NPC166014
Intermediate Similarity 0.7763 NPC27410
Intermediate Similarity 0.7752 NPC471668
Intermediate Similarity 0.7734 NPC268160
Intermediate Similarity 0.7718 NPC26601
Intermediate Similarity 0.7686 NPC289381
Intermediate Similarity 0.7686 NPC155847
Intermediate Similarity 0.7676 NPC211468
Intermediate Similarity 0.7676 NPC170170
Intermediate Similarity 0.7676 NPC219233
Intermediate Similarity 0.7674 NPC35797
Intermediate Similarity 0.7674 NPC147179
Intermediate Similarity 0.7674 NPC192948
Intermediate Similarity 0.7662 NPC1229
Intermediate Similarity 0.7656 NPC715
Intermediate Similarity 0.7638 NPC95716
Intermediate Similarity 0.7638 NPC77772
Intermediate Similarity 0.7634 NPC48342
Intermediate Similarity 0.7634 NPC164649
Intermediate Similarity 0.7622 NPC323123
Intermediate Similarity 0.7615 NPC477137
Intermediate Similarity 0.7615 NPC38893
Intermediate Similarity 0.7615 NPC308828
Intermediate Similarity 0.7615 NPC219112
Intermediate Similarity 0.7615 NPC308311
Intermediate Similarity 0.7603 NPC185838
Intermediate Similarity 0.76 NPC151477
Intermediate Similarity 0.7578 NPC46940
Intermediate Similarity 0.7576 NPC126002
Intermediate Similarity 0.7576 NPC93071
Intermediate Similarity 0.7576 NPC42657
Intermediate Similarity 0.7557 NPC477136
Intermediate Similarity 0.7557 NPC172219
Intermediate Similarity 0.7557 NPC304510
Intermediate Similarity 0.7557 NPC16030
Intermediate Similarity 0.7552 NPC150712
Intermediate Similarity 0.7548 NPC324144
Intermediate Similarity 0.7541 NPC211885
Intermediate Similarity 0.7537 NPC109151
Intermediate Similarity 0.7533 NPC81733
Intermediate Similarity 0.7533 NPC326316
Intermediate Similarity 0.7532 NPC226428
Intermediate Similarity 0.7519 NPC318552
Intermediate Similarity 0.7519 NPC321133
Intermediate Similarity 0.7519 NPC190501
Intermediate Similarity 0.7519 NPC99734
Intermediate Similarity 0.7516 NPC158376
Intermediate Similarity 0.7516 NPC306555
Intermediate Similarity 0.7516 NPC205421
Intermediate Similarity 0.7516 NPC12053
Intermediate Similarity 0.7516 NPC145832
Intermediate Similarity 0.7516 NPC298979
Intermediate Similarity 0.7516 NPC81218
Intermediate Similarity 0.7516 NPC117188
Intermediate Similarity 0.7516 NPC474931
Intermediate Similarity 0.75 NPC469609
Intermediate Similarity 0.75 NPC212794
Intermediate Similarity 0.75 NPC136508
Intermediate Similarity 0.75 NPC329969
Intermediate Similarity 0.75 NPC78222
Intermediate Similarity 0.75 NPC476151
Intermediate Similarity 0.75 NPC470770
Intermediate Similarity 0.75 NPC253043
Intermediate Similarity 0.75 NPC196447
Intermediate Similarity 0.75 NPC13504
Intermediate Similarity 0.75 NPC321505
Intermediate Similarity 0.75 NPC255607
Intermediate Similarity 0.75 NPC477563
Intermediate Similarity 0.75 NPC179825
Intermediate Similarity 0.75 NPC3375
Intermediate Similarity 0.75 NPC266937
Intermediate Similarity 0.75 NPC471671
Intermediate Similarity 0.75 NPC96603
Intermediate Similarity 0.75 NPC306843
Intermediate Similarity 0.75 NPC191376
Intermediate Similarity 0.7481 NPC141001
Intermediate Similarity 0.7481 NPC92
Intermediate Similarity 0.7481 NPC469663
Intermediate Similarity 0.748 NPC58865
Intermediate Similarity 0.7468 NPC221864
Intermediate Similarity 0.7463 NPC328504
Intermediate Similarity 0.7462 NPC471534
Intermediate Similarity 0.7452 NPC81247
Intermediate Similarity 0.7452 NPC35627
Intermediate Similarity 0.7452 NPC124657
Intermediate Similarity 0.7452 NPC476573
Intermediate Similarity 0.745 NPC246587
Intermediate Similarity 0.745 NPC428
Intermediate Similarity 0.745 NPC135538
Intermediate Similarity 0.745 NPC476571
Intermediate Similarity 0.745 NPC24233
Intermediate Similarity 0.745 NPC147390
Intermediate Similarity 0.7447 NPC132847
Intermediate Similarity 0.7444 NPC469644
Intermediate Similarity 0.7442 NPC177962
Intermediate Similarity 0.7442 NPC62867
Intermediate Similarity 0.744 NPC117115
Intermediate Similarity 0.7429 NPC257390
Intermediate Similarity 0.7422 NPC474149
Intermediate Similarity 0.7419 NPC235143
Intermediate Similarity 0.7419 NPC475780
Intermediate Similarity 0.7419 NPC119649
Intermediate Similarity 0.7419 NPC230956
Intermediate Similarity 0.7419 NPC205255
Intermediate Similarity 0.7419 NPC271388
Intermediate Similarity 0.7407 NPC77569
Intermediate Similarity 0.7407 NPC142198
Intermediate Similarity 0.7405 NPC469719
Intermediate Similarity 0.7403 NPC79328
Intermediate Similarity 0.74 NPC103379
Intermediate Similarity 0.74 NPC477565
Intermediate Similarity 0.7388 NPC135467
Intermediate Similarity 0.7388 NPC260832
Intermediate Similarity 0.7385 NPC321589
Intermediate Similarity 0.7385 NPC322239
Intermediate Similarity 0.7383 NPC144863
Intermediate Similarity 0.7383 NPC253883
Intermediate Similarity 0.7383 NPC90844
Intermediate Similarity 0.7383 NPC95075
Intermediate Similarity 0.7381 NPC21594
Intermediate Similarity 0.7381 NPC271274
Intermediate Similarity 0.7377 NPC225464
Intermediate Similarity 0.7376 NPC33338
Intermediate Similarity 0.7376 NPC300020
Intermediate Similarity 0.7376 NPC302171
Intermediate Similarity 0.7372 NPC80759
Intermediate Similarity 0.7372 NPC79402
Intermediate Similarity 0.7361 NPC193528
Intermediate Similarity 0.7351 NPC192768
Intermediate Similarity 0.7351 NPC151895
Intermediate Similarity 0.7351 NPC97221
Intermediate Similarity 0.7351 NPC220858
Intermediate Similarity 0.7351 NPC88249
Intermediate Similarity 0.7348 NPC474387
Intermediate Similarity 0.7348 NPC82963
Intermediate Similarity 0.7348 NPC474358
Intermediate Similarity 0.7348 NPC137496
Intermediate Similarity 0.7348 NPC247858
Intermediate Similarity 0.7348 NPC257540
Intermediate Similarity 0.7348 NPC154511
Intermediate Similarity 0.7344 NPC314187
Intermediate Similarity 0.7344 NPC65855
Intermediate Similarity 0.7344 NPC292758
Intermediate Similarity 0.7338 NPC186063
Intermediate Similarity 0.7333 NPC32322
Intermediate Similarity 0.7333 NPC259703
Intermediate Similarity 0.7328 NPC118202
Intermediate Similarity 0.7323 NPC320439
Intermediate Similarity 0.7317 NPC298339
Intermediate Similarity 0.7317 NPC92730
Intermediate Similarity 0.7312 NPC118274
Intermediate Similarity 0.7312 NPC168753
Intermediate Similarity 0.7308 NPC228425
Intermediate Similarity 0.7303 NPC8337
Intermediate Similarity 0.7303 NPC85747
Intermediate Similarity 0.7293 NPC38458
Intermediate Similarity 0.7293 NPC299180
Intermediate Similarity 0.7293 NPC311737
Intermediate Similarity 0.729 NPC476572
Intermediate Similarity 0.7285 NPC207824
Intermediate Similarity 0.7285 NPC219162
Intermediate Similarity 0.7285 NPC60538
Intermediate Similarity 0.7285 NPC92541
Intermediate Similarity 0.7279 NPC249340
Intermediate Similarity 0.7279 NPC162935
Intermediate Similarity 0.7279 NPC253627
Intermediate Similarity 0.7278 NPC134858
Intermediate Similarity 0.7273 NPC27323
Intermediate Similarity 0.7273 NPC249797
Intermediate Similarity 0.7273 NPC316301
Intermediate Similarity 0.7273 NPC110416
Intermediate Similarity 0.7273 NPC189266
Intermediate Similarity 0.7273 NPC2413
Intermediate Similarity 0.7273 NPC325871
Intermediate Similarity 0.7273 NPC54379
Intermediate Similarity 0.7273 NPC99659
Intermediate Similarity 0.7273 NPC5238
Intermediate Similarity 0.7273 NPC317254
Intermediate Similarity 0.7273 NPC204828
Intermediate Similarity 0.7273 NPC184026
Intermediate Similarity 0.7273 NPC172765

Drug Structure

External Identifiers

TTD   DAP000268; DNC000541
DrugBank   DB00854
ChEMBL   CHEMBL592
IUPHAR/BPS   7595
PharmaGKB   PA164744368
KEGG Drug   D08123
PubChem CID   5359272
ChEBI   6444
CAS Number  77-07-6

Drug Properties

Molecular Weight  257.18
ALogP  -0.9995
MLogP  3.11
XLogP  3.688
HDA  1
HBD  1
Rotatable Bonds  2
TPSA  23.47
RO5 Violation  0