Structure

Physi-Chem Properties

Molecular Weight:  225.09
Volume:  200.62
LogP:  -2.032
LogD:  -1.766
LogS:  -2.042
# Rotatable Bonds:  4
TPSA:  119.78
# H-Bond Aceptor:  8
# H-Bond Donor:  4
# Rings:  2
# Heavy Atoms:  8

MedChem Properties

QED Drug-Likeness Score:  0.473
Synthetic Accessibility Score:  3.195
Fsp3:  0.375
Lipinski Rule-of-5:  Accepted
Pfizer Rule:  Accepted
GSK Rule:  Accepted
BMS Rule:  0
Golden Triangle Rule:  Accepted
Chelating Alert:  0
PAINS Alert:  0

ADMET Properties (ADMETlab2.0)

ADMET: Absorption

Caco-2 Permeability:  -6.176
MDCK Permeability:  3.47631867043674e-05
Pgp-inhibitor:  0.0
Pgp-substrate:  0.842
Human Intestinal Absorption (HIA):  0.971
20% Bioavailability (F20%):  0.998
30% Bioavailability (F30%):  0.995

ADMET: Distribution

Blood-Brain-Barrier Penetration (BBB):  0.84
Plasma Protein Binding (PPB):  12.529134750366211%
Volume Distribution (VD):  0.797
Pgp-substrate:  83.5920181274414%

ADMET: Metabolism

CYP1A2-inhibitor:  0.008
CYP1A2-substrate:  0.923
CYP2C19-inhibitor:  0.034
CYP2C19-substrate:  0.033
CYP2C9-inhibitor:  0.005
CYP2C9-substrate:  0.005
CYP2D6-inhibitor:  0.001
CYP2D6-substrate:  0.018
CYP3A4-inhibitor:  0.007
CYP3A4-substrate:  0.09

ADMET: Excretion

Clearance (CL):  4.17
Half-life (T1/2):  0.945

ADMET: Toxicity

hERG Blockers:  0.032
Human Hepatotoxicity (H-HT):  0.995
Drug-inuced Liver Injury (DILI):  0.991
AMES Toxicity:  0.866
Rat Oral Acute Toxicity:  0.279
Maximum Recommended Daily Dose:  0.008
Skin Sensitization:  0.483
Carcinogencity:  0.985
Eye Corrosion:  0.003
Eye Irritation:  0.27
Respiratory Toxicity:  0.949

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General Info & Identifiers & Properties  
Structure MOL file  
Source Organisms  
Biological Activities  
Similar NPs/Drugs  

  Natural Product: NPC35410

Natural Product ID:  NPC35410
Common Name*:   MKUXAQIIEYXACX-UHFFFAOYSA-N
IUPAC Name:   n.a.
Synonyms:  
Standard InCHIKey:  MKUXAQIIEYXACX-UHFFFAOYSA-N
Standard InCHI:  InChI=1S/C8H11N5O3/c9-8-11-6-5(7(15)12-8)10-3-13(6)4-16-2-1-14/h3,14H,1-2,4H2,(H3,9,11,12,15)
SMILES:  C(COCn1cnc2c1[nH]c(=N)nc2O)O
Synthetic Gene Cluster:   n.a.
ChEMBL Identifier:   n.a.
PubChem CID:   2022
Chemical Classification**:  
  • CHEMONTID:0000000 [Organic compounds]
    • [CHEMONTID:0000002] Organoheterocyclic compounds
      • [CHEMONTID:0001797] Imidazopyrimidines
        • [CHEMONTID:0000245] Purines and purine derivatives
          • [CHEMONTID:0000597] Purinones
            • [CHEMONTID:0000246] Hypoxanthines

*Note: the InCHIKey will be temporarily assigned as the "Common Name" if no IUPAC name or alternative short name is available.
**Note: the Chemical Classification was calculated by NPClassifier Version 1.5. Reference: PMID:34662515.

  Species Source

Organism ID Organism Name Taxonomy Level Family SuperKingdom Isolation Part Collection Location Collection Time Reference
NPO15768 Lyonia ovalifolia Species Ericaceae Eukaryota Twigs; Leaves n.a. n.a. PMID[27792321]
NPO24074 Jatropha dioica Species Euphorbiaceae Eukaryota n.a. n.a. n.a. PMID[28771358]
NPO1436 Houttuynia cordata Species Saururaceae Eukaryota n.a. n.a. n.a. PMID[29099182]
NPO9925 Rhododendron latoucheae Species Ericaceae Eukaryota Twigs; Leaves n.a. n.a. PMID[30106288]
NPO40504 Epicoccum nigrum HDN17-88 Strain Didymellaceae Eukaryota n.a. n.a. n.a. PMID[31975590]
NPO1436 Houttuynia cordata Species Saururaceae Eukaryota n.a. n.a. n.a. Database[HerDing]
NPO15768 Lyonia ovalifolia Species Ericaceae Eukaryota n.a. n.a. n.a. Database[HerDing]
NPO1436 Houttuynia cordata Species Saururaceae Eukaryota n.a. n.a. n.a. Database[TCMID]
NPO15768 Lyonia ovalifolia Species Ericaceae Eukaryota n.a. n.a. n.a. Database[TCMID]
NPO15768 Lyonia ovalifolia Species Ericaceae Eukaryota n.a. n.a. n.a. Database[TCM_Taiwan]
NPO1436 Houttuynia cordata Species Saururaceae Eukaryota n.a. n.a. n.a. Database[TCM_Taiwan]
NPO1436 Houttuynia cordata Species Saururaceae Eukaryota n.a. n.a. n.a. Database[TM-MC]
NPO24074 Jatropha dioica Species Euphorbiaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO9925 Rhododendron latoucheae Species Ericaceae Eukaryota n.a. n.a. n.a. Database[UNPD]
NPO15768 Lyonia ovalifolia Species Ericaceae Eukaryota n.a. n.a. n.a. Database[UNPD]

☑ Note for Reference:
In addition to directly collecting NP source organism data from primary literature (where reference will provided as NCBI PMID or DOI links), NPASS also integrated them from below databases:
UNPD: Universal Natural Products Database [PMID: 23638153].
StreptomeDB: a database of streptomycetes natural products [PMID: 33051671].
TM-MC: a database of medicinal materials and chemical compounds in Northeast Asian traditional medicine [PMID: 26156871].
TCM@Taiwan: a Traditional Chinese Medicine database [PMID: 21253603].
TCMID: a Traditional Chinese Medicine database [PMID: 29106634].
TCMSP: The traditional Chinese medicine systems pharmacology database and analysis platform [PMID: 24735618].
HerDing: a herb recommendation system to treat diseases using genes and chemicals [PMID: 26980517].
MetaboLights: a metabolomics database [PMID: 27010336].
FooDB: a database of constituents, chemistry and biology of food species [www.foodb.ca].

  NP Quantity Composition/Concentration

Organism ID NP ID Organism Material Preparation Organism Part NP Quantity (Standard) NP Quantity (Minimum) NP Quantity (Maximum) Quantity Unit Reference

☑ Note for Reference:
In addition to directly collecting NP quantitative data from primary literature (where reference will provided as NCBI PMID or DOI links), NPASS also integrated NP quantitative records for specific NP domains (e.g., NPS from foods or herbs) from domain-specific databases. These databases include:
DUKE: Dr. Duke's Phytochemical and Ethnobotanical Databases.
PHENOL EXPLORER: is the first comprehensive database on polyphenol content in foods [PMID: 24103452], its homepage can be accessed at here.
FooDB: a database of constituents, chemistry and biology of food species [www.foodb.ca].

  Biological Activity

Target ID Target Type Target Name Target Organism Activity Type Activity Relation Value Unit Reference
NPT2192 Cell Line HEL Homo sapiens IC50 = 24.0 ug.mL-1 DOI[10.1016/S0960-894X(97)00149-2]
NPT2192 Cell Line HEL Homo sapiens IC50 = 26.0 ug.mL-1 DOI[10.1016/S0960-894X(97)00149-2]
NPT165 Cell Line HeLa Homo sapiens CC50 = 200.0 ug.mL-1 DOI[10.1016/S0960-894X(97)00149-2]
NPT4230 Individual Protein Human herpesvirus 1 DNA polymerase Herpes simplex virus (type 1 / strain 17) Inhibition = 79.0 % PMID[2848125]
NPT4951 Cell Line E6SM Homo sapiens CC50 > 400.0 ug.mL-1 PMID[8709116]
NPT189 Cell Line Vero Chlorocebus aethiops ID50 = 1100.0 uM PMID[2993615]
NPT4951 Cell Line E6SM Homo sapiens MIC = 0.077 ug.mL-1 PMID[11472207]
NPT4951 Cell Line E6SM Homo sapiens MIC > 400.0 ug.mL-1 PMID[11472207]
NPT4951 Cell Line E6SM Homo sapiens MIC = 48.0 ug.mL-1 PMID[11472207]
NPT4951 Cell Line E6SM Homo sapiens MIC = 0.384 ug.mL-1 PMID[11472207]
NPT189 Cell Line Vero Chlorocebus aethiops CC50 > 400000.0 nM PMID[14584951]
NPT189 Cell Line Vero Chlorocebus aethiops EC50 = 40.0 ug.mL-1 PMID[11677126]
NPT189 Cell Line Vero Chlorocebus aethiops EC50 = 0.5 ug.mL-1 PMID[11677126]
NPT189 Cell Line Vero Chlorocebus aethiops CC50 > 100.0 ug.mL-1 PMID[11677126]
NPT4951 Cell Line E6SM Homo sapiens MIC = 0.07 ug.mL-1 PMID[1315394]
NPT4951 Cell Line E6SM Homo sapiens MIC = 0.04 ug.mL-1 PMID[1315394]
NPT4951 Cell Line E6SM Homo sapiens MIC = 0.02 ug.mL-1 PMID[1315394]
NPT4951 Cell Line E6SM Homo sapiens MIC = 70.0 ug.mL-1 PMID[1315394]
NPT4951 Cell Line E6SM Homo sapiens MIC = 10.0 ug.mL-1 PMID[1315394]
NPT4951 Cell Line E6SM Homo sapiens MIC = 0.015 ug.mL-1 PMID[1315394]
NPT189 Cell Line Vero Chlorocebus aethiops IC50 = 50.0 ug.mL-1 DOI[10.1016/S0960-894X(97)00365-X]
NPT2192 Cell Line HEL Homo sapiens IC50 > 50.0 ug.mL-1 DOI[10.1016/S0960-894X(97)00365-X]
NPT1353 Cell Line CCRF-HSB-2 Homo sapiens IC50 > 100.0 ug.mL-1 PMID[9216836]
NPT189 Cell Line Vero Chlorocebus aethiops TD50 = 240.0 ug ml-1 PMID[2213836]
NPT4951 Cell Line E6SM Homo sapiens MIC = 350.0 ug.mL-1 PMID[7932543]
NPT2192 Cell Line HEL Homo sapiens MIC > 200.0 ug.mL-1 PMID[7932543]
NPT80 Cell Line Raji Homo sapiens ED50 = 3.8 ug ml-1 PMID[2329551]
NPT80 Cell Line Raji Homo sapiens ID50 > 100.0 ug ml-1 PMID[2329551]
NPT2192 Cell Line HEL Homo sapiens MIC = 4.0 ug.mL-1 PMID[8176708]
NPT2192 Cell Line HEL Homo sapiens MIC = 80.0 ug.mL-1 PMID[8176708]
NPT2192 Cell Line HEL Homo sapiens MIC = 50.0 ug.mL-1 PMID[8176708]
NPT2192 Cell Line HEL Homo sapiens MIC = 35.0 ug.mL-1 PMID[8176708]
NPT5206 Cell Line ESM MIC > 400.0 ug.mL-1 PMID[8176708]
NPT2192 Cell Line HEL Homo sapiens MIC > 200.0 ug.mL-1 PMID[8176708]
NPT2192 Cell Line HEL Homo sapiens IC50 > 200000.0 nM PMID[10579812]
NPT189 Cell Line Vero Chlorocebus aethiops ID50 = 100.0 ug ml-1 PMID[2157012]
NPT165 Cell Line HeLa Homo sapiens CC50 > 400000.0 nM PMID[15109620]
NPT859 Cell Line HFF Homo sapiens IC50 > 100000.0 nM PMID[2840500]
NPT2192 Cell Line HEL Homo sapiens MIC > 200.0 ug.mL-1 PMID[8393114]
NPT189 Cell Line Vero Chlorocebus aethiops ED50 = 0.5 uM PMID[8289203]
NPT189 Cell Line Vero Chlorocebus aethiops CD50 > 50.0 uM PMID[8289203]
NPT1755 Individual Protein Thymidine kinase, cytosolic Homo sapiens Activity = 23.0 % PMID[3016263]
NPT189 Cell Line Vero Chlorocebus aethiops ID50 = 0.5 uM PMID[3016263]
NPT4951 Cell Line E6SM Homo sapiens MIC = 0.04 ug.mL-1 PMID[9135038]
NPT4951 Cell Line E6SM Homo sapiens MIC = 0.07 ug.mL-1 PMID[9135038]
NPT4951 Cell Line E6SM Homo sapiens MIC > 200.0 ug.mL-1 PMID[9135038]
NPT4951 Cell Line E6SM Homo sapiens MIC = 70.0 ug.mL-1 PMID[9135038]
NPT4951 Cell Line E6SM Homo sapiens MIC = 400.0 ug.mL-1 PMID[9135038]
NPT2192 Cell Line HEL Homo sapiens MIC = 0.1 ug.mL-1 PMID[9135038]
NPT2192 Cell Line HEL Homo sapiens MIC = 5.0 ug.mL-1 PMID[9135038]
NPT2192 Cell Line HEL Homo sapiens MIC > 200.0 ug.mL-1 PMID[9135038]
NPT404 Cell Line CCRF-CEM Homo sapiens ID50 > 100.0 n.a. PMID[10891113]
NPT404 Cell Line CCRF-CEM Homo sapiens ID50 > 200.0 n.a. PMID[10891113]
NPT189 Cell Line Vero Chlorocebus aethiops IC50 = 3800.0 nM PMID[3040998]
NPT189 Cell Line Vero Chlorocebus aethiops IC50 = 2500.0 nM PMID[3040998]
NPT171 Cell Line MRC5 Homo sapiens IC90 = 4800.0 nM PMID[3040998]
NPT171 Cell Line MRC5 Homo sapiens IC90 = 700.0 nM PMID[3040998]
NPT171 Cell Line MRC5 Homo sapiens IC90 = 1400.0 nM PMID[3040998]
NPT171 Cell Line MRC5 Homo sapiens IC90 = 900.0 nM PMID[3040998]
NPT171 Cell Line MRC5 Homo sapiens IC90 = 1200.0 nM PMID[3040998]
NPT171 Cell Line MRC5 Homo sapiens IC90 = 300.0 nM PMID[3040998]
NPT1374 Cell Line WI-38 Homo sapiens ID50 = 4.0 uM PMID[1316966]
NPT1374 Cell Line WI-38 Homo sapiens ID50 = 2.0 uM PMID[1316966]
NPT1374 Cell Line WI-38 Homo sapiens ID50 = 220.0 uM PMID[1316966]
NPT1374 Cell Line WI-38 Homo sapiens ID50 = 110.0 uM PMID[1316966]
NPT1374 Cell Line WI-38 Homo sapiens ID50 = 0.2 uM PMID[1316966]
NPT1374 Cell Line WI-38 Homo sapiens ID50 = 0.8 uM PMID[1316966]
NPT1374 Cell Line WI-38 Homo sapiens ID50 = 40.0 uM PMID[1316966]
NPT1374 Cell Line WI-38 Homo sapiens ID50 > 750.0 uM PMID[1316966]
NPT189 Cell Line Vero Chlorocebus aethiops ID50 = 0.9 ug ml-1 PMID[2157013]
NPT189 Cell Line Vero Chlorocebus aethiops Therapeutic index > 240.3 n.a. PMID[2157013]
NPT189 Cell Line Vero Chlorocebus aethiops ID50 > 300.0 ug ml-1 PMID[1848298]
NPT165 Cell Line HeLa Homo sapiens IC50 = 1900.0 nM PMID[7752206]
NPT165 Cell Line HeLa Homo sapiens IC50 > 200000.0 nM PMID[7752206]
NPT189 Cell Line Vero Chlorocebus aethiops MIC50 = 4.3 ug.mL-1 PMID[3033247]
NPT2192 Cell Line HEL Homo sapiens CC50 > 200000.0 nM PMID[10866384]
NPT189 Cell Line Vero Chlorocebus aethiops MIC = 1.3 ug.mL-1 PMID[7629793]
NPT189 Cell Line Vero Chlorocebus aethiops IC50 > 50000.0 nM PMID[10999490]
NPT859 Cell Line HFF Homo sapiens IC50 > 100000.0 nM PMID[2163453]
NPT859 Cell Line HFF Homo sapiens IC50 > 100000.0 nM PMID[2175356]
NPT137 Cell Line L1210 Mus musculus MIC = 55.0 ug.mL-1 PMID[2455050]
NPT1759 Cell Line FM3A Mus musculus MIC = 66.0 ug.mL-1 PMID[2455050]
NPT189 Cell Line Vero Chlorocebus aethiops ED50 = 0.04 uM PMID[1548681]
NPT189 Cell Line Vero Chlorocebus aethiops ED50 > 1300.0 uM PMID[1548681]
NPT189 Cell Line Vero Chlorocebus aethiops EC50 = 0.32 ug.mL-1 DOI[10.1016/0960-894X(95)00395-A]
NPT189 Cell Line Vero Chlorocebus aethiops EC50 = 0.39 ug.mL-1 DOI[10.1016/0960-894X(95)00395-A]
NPT189 Cell Line Vero Chlorocebus aethiops EC50 = 6000.0 nM DOI[10.1016/0960-894X(95)00208-B]
NPT189 Cell Line Vero Chlorocebus aethiops EC50 = 3000.0 nM DOI[10.1016/0960-894X(95)00208-B]
NPT171 Cell Line MRC5 Homo sapiens EC50 = 18000.0 nM DOI[10.1016/0960-894X(95)00208-B]
NPT189 Cell Line Vero Chlorocebus aethiops CC50 > 100000.0 nM DOI[10.1016/0960-894X(95)00208-B]
NPT171 Cell Line MRC5 Homo sapiens CC50 >= 100000.0 nM DOI[10.1016/0960-894X(95)00208-B]
NPT189 Cell Line Vero Chlorocebus aethiops IC50 = 100.0 nM PMID[2991522]
NPT1755 Individual Protein Thymidine kinase, cytosolic Homo sapiens Inhibition = 69.0 % PMID[2991522]
NPT2192 Cell Line HEL Homo sapiens MIC > 150000.0 nM PMID[11495586]
NPT2192 Cell Line HEL Homo sapiens EC50 = 4530.0 nM PMID[11495586]
NPT2192 Cell Line HEL Homo sapiens EC50 = 4090.0 nM PMID[11495586]
NPT2192 Cell Line HEL Homo sapiens EC50 = 41000.0 nM PMID[11495586]
NPT2192 Cell Line HEL Homo sapiens EC50 = 63000.0 nM PMID[11495586]
NPT189 Cell Line Vero Chlorocebus aethiops ID50 = 0.2 ug ml-1 DOI[10.1016/S0960-894X(01)80719-8]
NPT189 Cell Line Vero Chlorocebus aethiops ID50 = 0.6 ug ml-1 DOI[10.1016/S0960-894X(01)80719-8]
NPT189 Cell Line Vero Chlorocebus aethiops ID50 > 300.0 ug ml-1 DOI[10.1016/S0960-894X(01)80719-8]
NPT5206 Cell Line ESM MIC = 0.02 ug.mL-1 PMID[1652016]
NPT5206 Cell Line ESM MIC = 0.007 ug.mL-1 PMID[1652016]
NPT5206 Cell Line ESM MIC = 0.01 ug.mL-1 PMID[1652016]
NPT5206 Cell Line ESM MIC = 0.07 ug.mL-1 PMID[1652016]
NPT5206 Cell Line ESM MIC > 200.0 ug.mL-1 PMID[1652016]
NPT5206 Cell Line ESM MIC = 100.0 ug.mL-1 PMID[1652016]
NPT5206 Cell Line ESM MIC = 40.0 ug.mL-1 PMID[1652016]
NPT2192 Cell Line HEL Homo sapiens MIC = 0.3 ug.mL-1 PMID[1652016]
NPT2192 Cell Line HEL Homo sapiens MIC = 0.2 ug.mL-1 PMID[1652016]
NPT2192 Cell Line HEL Homo sapiens MIC = 10.0 ug.mL-1 PMID[1652016]
NPT2192 Cell Line HEL Homo sapiens MIC = 5.0 ug.mL-1 PMID[1652016]
NPT2192 Cell Line HEL Homo sapiens MIC = 15.0 ug.mL-1 PMID[1652016]
NPT5206 Cell Line ESM MIC = 400.0 ug.mL-1 PMID[1652016]
NPT2192 Cell Line HEL Homo sapiens MIC = 200.0 ug.mL-1 PMID[1652016]
NPT189 Cell Line Vero Chlorocebus aethiops IC50 = 1200.0 nM PMID[1323678]
NPT2192 Cell Line HEL Homo sapiens CC50 > 200.0 ug.mL-1 PMID[10197958]
NPT137 Cell Line L1210 Mus musculus ID50 = 13.0 ug ml-1 PMID[6092636]
NPT137 Cell Line L1210 Mus musculus ID50 = 367.0 ug ml-1 PMID[6092636]
NPT137 Cell Line L1210 Mus musculus ID50 = 50.0 ug ml-1 PMID[6092636]
NPT404 Cell Line CCRF-CEM Homo sapiens IC50 > 440000.0 nM PMID[11814776]
NPT2192 Cell Line HEL Homo sapiens CC50 > 200000.0 nM PMID[11212118]
NPT6172 Cell Line Human neoplasticcell line IC50 > 100000.0 nM PMID[2163454]
NPT189 Cell Line Vero Chlorocebus aethiops IC50 = 0.1 ug.mL-1 DOI[10.1016/S0960-894X(01)80693-4]
NPT189 Cell Line Vero Chlorocebus aethiops IC50 = 0.5 ug.mL-1 DOI[10.1016/S0960-894X(01)80693-4]
NPT189 Cell Line Vero Chlorocebus aethiops CC50 > 10.0 ug.mL-1 DOI[10.1016/S0960-894X(01)80693-4]
NPT189 Cell Line Vero Chlorocebus aethiops ID50 = 0.01 ug ml-1 PMID[2299637]
NPT4951 Cell Line E6SM Homo sapiens MIC = 0.08 ug.mL-1 PMID[11858989]
NPT4951 Cell Line E6SM Homo sapiens MIC = 48.0 ug.mL-1 PMID[11858989]
NPT2192 Cell Line HEL Homo sapiens MIC = 1.1 ug.mL-1 PMID[11858989]
NPT165 Cell Line HeLa Homo sapiens MIC = 12.3 ug.mL-1 PMID[11858989]
NPT4951 Cell Line E6SM Homo sapiens MIC > 400.0 ug.mL-1 PMID[11858989]
NPT189 Cell Line Vero Chlorocebus aethiops ID50 = 0.5 ug ml-1 PMID[1648622]
NPT189 Cell Line Vero Chlorocebus aethiops ID50 = 2.4 ug ml-1 PMID[1648622]
NPT171 Cell Line MRC5 Homo sapiens ID50 = 38.4 ug ml-1 PMID[1648622]
NPT189 Cell Line Vero Chlorocebus aethiops ID50 > 100.0 ug ml-1 PMID[1648622]
NPT859 Cell Line HFF Homo sapiens IC50 > 100000.0 nM PMID[2846837]
NPT25 Cell Line MT4 Homo sapiens CC50 > 76.6 ug.mL-1 PMID[12161143]
NPT25 Cell Line MT4 Homo sapiens CC50 > 11.4 ug.mL-1 PMID[12161143]
NPT189 Cell Line Vero Chlorocebus aethiops IC50 = 7540.0 nM PMID[9685239]
NPT189 Cell Line Vero Chlorocebus aethiops IC50 = 37800.0 nM PMID[9685239]
NPT189 Cell Line Vero Chlorocebus aethiops IC50 > 88800.0 nM PMID[9685239]
NPT189 Cell Line Vero Chlorocebus aethiops IC50 = 138400.0 nM PMID[9685239]
NPT189 Cell Line Vero Chlorocebus aethiops IC50 = 111000.0 nM PMID[9685239]
NPT189 Cell Line Vero Chlorocebus aethiops IC50 = 130700.0 nM PMID[9685239]
NPT189 Cell Line Vero Chlorocebus aethiops IC50 = 189800.0 nM PMID[9685239]
NPT189 Cell Line Vero Chlorocebus aethiops IC50 = 444000.0 nM PMID[9685239]
NPT189 Cell Line Vero Chlorocebus aethiops IC50 = 378800.0 nM PMID[9685239]
NPT189 Cell Line Vero Chlorocebus aethiops IC50 = 6660.0 nM PMID[9685239]
NPT189 Cell Line Vero Chlorocebus aethiops IC50 > 44400.0 nM PMID[9685239]
NPT189 Cell Line Vero Chlorocebus aethiops IC50 = 62800.0 nM PMID[9685239]
NPT2192 Cell Line HEL Homo sapiens EC50 = 1500.0 nM PMID[11549457]
NPT2192 Cell Line HEL Homo sapiens EC50 = 1100.0 nM PMID[11549457]
NPT2192 Cell Line HEL Homo sapiens EC50 = 40000.0 nM PMID[11549457]
NPT2192 Cell Line HEL Homo sapiens EC50 = 44000.0 nM PMID[11549457]
NPT2192 Cell Line HEL Homo sapiens CC50 > 400000.0 nM PMID[11549457]
NPT171 Cell Line MRC5 Homo sapiens EC50 = 50000.0 nM PMID[10762044]
NPT189 Cell Line Vero Chlorocebus aethiops EC50 = 3000.0 nM PMID[10762044]
NPT171 Cell Line MRC5 Homo sapiens EC50 = 5000.0 nM PMID[10762044]
NPT189 Cell Line Vero Chlorocebus aethiops CC50 > 5000.0 nM PMID[10762044]
NPT137 Cell Line L1210 Mus musculus ID50 = 41.0 ug ml-1 PMID[2391680]
NPT1759 Cell Line FM3A Mus musculus ID50 = 17.0 ug ml-1 PMID[2391680]
NPT1759 Cell Line FM3A Mus musculus ID50 = 0.62 ug ml-1 PMID[2391680]
NPT1759 Cell Line FM3A Mus musculus ID50 = 0.0009 ug ml-1 PMID[2391680]
NPT80 Cell Line Raji Homo sapiens ID50 > 100.0 ug ml-1 PMID[2391680]
NPT5528 Cell Line MOLT-4F Homo sapiens ID50 > 100.0 ug ml-1 PMID[2391680]
NPT859 Cell Line HFF Homo sapiens EC50 = 1100.0 nM PMID[14584954]
NPT859 Cell Line HFF Homo sapiens EC50 = 1680.0 nM PMID[14584954]
NPT2192 Cell Line HEL Homo sapiens MIC = 0.001 ug.mL-1 PMID[1319491]
NPT2192 Cell Line HEL Homo sapiens MIC = 0.0007 ug.mL-1 PMID[1319491]
NPT2192 Cell Line HEL Homo sapiens MIC > 10.0 ug.mL-1 PMID[1319491]
NPT189 Cell Line Vero Chlorocebus aethiops ID50 = 0.01 ug ml-1 PMID[2709380]
NPT165 Cell Line HeLa Homo sapiens IC50 = 0.1 ug.mL-1 PMID[7473592]
NPT165 Cell Line HeLa Homo sapiens IC50 = 0.23 ug.mL-1 PMID[7473592]
NPT165 Cell Line HeLa Homo sapiens IC50 = 20.0 ug.mL-1 PMID[7473592]
NPT165 Cell Line HeLa Homo sapiens IC50 = 250.0 ug.mL-1 PMID[7473592]
NPT165 Cell Line HeLa Homo sapiens IC50 = 110.0 nM PMID[11356110]
NPT165 Cell Line HeLa Homo sapiens IC50 = 190.0 nM PMID[11356110]
NPT165 Cell Line HeLa Homo sapiens IC50 = 8710.0 nM PMID[11356110]
NPT165 Cell Line HeLa Homo sapiens IC50 = 26430.0 nM PMID[11356110]
NPT165 Cell Line HeLa Homo sapiens IC50 = 253640.0 nM PMID[11356110]
NPT1374 Cell Line WI-38 Homo sapiens ID50 > 800.0 uM PMID[8387600]
NPT2192 Cell Line HEL Homo sapiens CC50 > 200.0 ug.mL-1 PMID[7877148]
NPT2192 Cell Line HEL Homo sapiens IC50 = 0.04 ug.mL-1 PMID[7877148]
NPT2192 Cell Line HEL Homo sapiens IC50 = 0.15 ug.mL-1 PMID[7877148]
NPT2192 Cell Line HEL Homo sapiens IC50 = 3.0 ug.mL-1 PMID[7877148]
NPT2192 Cell Line HEL Homo sapiens IC50 = 5.0 ug.mL-1 PMID[7877148]
NPT2192 Cell Line HEL Homo sapiens IC50 = 20.0 ug.mL-1 PMID[7877148]
NPT2192 Cell Line HEL Homo sapiens IC50 = 15.0 ug.mL-1 PMID[7877148]
NPT1291 Individual Protein Purine nucleoside phosphorylase Homo sapiens Ki = 180000.0 nM PMID[8478902]
NPT189 Cell Line Vero Chlorocebus aethiops IC50 = 1.5 ug.mL-1 DOI[10.1016/S0960-894X(01)80236-5]
NPT189 Cell Line Vero Chlorocebus aethiops CC50 = 820.0 ug.mL-1 PMID[10649983]
NPT2192 Cell Line HEL Homo sapiens IC50 = 3.4 ug.mL-1 PMID[10649983]
NPT171 Cell Line MRC5 Homo sapiens IC50 = 0.29 ug.mL-1 PMID[10649983]
NPT171 Cell Line MRC5 Homo sapiens IC50 = 0.25 ug.mL-1 PMID[10649983]
NPT171 Cell Line MRC5 Homo sapiens IC50 = 1.3 ug.mL-1 PMID[10649983]
NPT2192 Cell Line HEL Homo sapiens IC50 = 5.4 ug.mL-1 PMID[10649983]
NPT2846 Cell Line BHK-21 Cricetulus griseus EC50 = 2000.0 nM PMID[8863795]
NPT189 Cell Line Vero Chlorocebus aethiops IC50 = 0.81 ug.mL-1 PMID[9548818]
NPT189 Cell Line Vero Chlorocebus aethiops CC50 = 820.0 ug.mL-1 PMID[9548818]
NPT859 Cell Line HFF Homo sapiens IC50 = 2.7 ug.mL-1 PMID[9548818]
NPT189 Cell Line Vero Chlorocebus aethiops MIC = 1.3 ug.mL-1 PMID[8388470]
NPT189 Cell Line Vero Chlorocebus aethiops MIC = 0.29 ug.mL-1 PMID[8388470]
NPT189 Cell Line Vero Chlorocebus aethiops MIC = 0.14 ug.mL-1 PMID[8388470]
NPT189 Cell Line Vero Chlorocebus aethiops MIC = 43.0 ug.mL-1 PMID[8388470]
NPT189 Cell Line Vero Chlorocebus aethiops MIC = 7.8 ug.mL-1 PMID[8388470]
NPT189 Cell Line Vero Chlorocebus aethiops MIC = 11.0 ug.mL-1 PMID[8388470]
NPT189 Cell Line Vero Chlorocebus aethiops MIC = 77.0 ug.mL-1 PMID[8388470]
NPT859 Cell Line HFF Homo sapiens IC50 > 100000.0 nM PMID[8784444]
NPT91 Cell Line KB Homo sapiens IC50 > 100000.0 nM PMID[8784444]
NPT189 Cell Line Vero Chlorocebus aethiops IC50 = 6700.0 nM PMID[2153202]
NPT171 Cell Line MRC5 Homo sapiens IC50 = 2500.0 nM PMID[2153202]
NPT171 Cell Line MRC5 Homo sapiens IC50 = 20000.0 nM PMID[2153202]
NPT80 Cell Line Raji Homo sapiens EC50 = 2900.0 nM PMID[8394933]
NPT91 Cell Line KB Homo sapiens IC50 > 100000.0 nM PMID[8071942]
NPT171 Cell Line MRC5 Homo sapiens MIC50 = 1300.0 nM PMID[1654428]
NPT189 Cell Line Vero Chlorocebus aethiops MIC50 = 1800.0 nM PMID[1654428]
NPT171 Cell Line MRC5 Homo sapiens MIC50 = 14500.0 nM PMID[1654428]
NPT171 Cell Line MRC5 Homo sapiens MIC50 = 100000.0 nM PMID[1654428]
NPT189 Cell Line Vero Chlorocebus aethiops ID50 > 500.0 n.a. PMID[1654428]
NPT91 Cell Line KB Homo sapiens IC50 > 100000.0 nM PMID[1310744]
NPT4951 Cell Line E6SM Homo sapiens MIC = 0.075 ug.mL-1 PMID[9784109]
NPT4951 Cell Line E6SM Homo sapiens MIC = 0.38 ug.mL-1 PMID[9784109]
NPT4951 Cell Line E6SM Homo sapiens MIC = 1.92 ug.mL-1 PMID[9784109]
NPT4951 Cell Line E6SM Homo sapiens MIC = 0.1 ug.mL-1 PMID[9784109]
NPT189 Cell Line Vero Chlorocebus aethiops EC50 = 6000.0 nM PMID[10987418]
NPT2192 Cell Line HEL Homo sapiens IC50 = 780.0 nM PMID[10411487]
NPT2192 Cell Line HEL Homo sapiens IC50 = 160.0 nM PMID[10411487]
NPT2192 Cell Line HEL Homo sapiens IC50 = 17000.0 nM PMID[10411487]
NPT2192 Cell Line HEL Homo sapiens IC50 = 12000.0 nM PMID[10411487]
NPT2192 Cell Line HEL Homo sapiens IC50 > 50000.0 nM PMID[10411487]
NPT2192 Cell Line HEL Homo sapiens IC50 > 100000.0 nM PMID[10411487]
NPT2192 Cell Line HEL Homo sapiens IC50 = 0.1 ug.mL-1 PMID[8246242]
NPT2192 Cell Line HEL Homo sapiens IC50 = 4.0 ug.mL-1 PMID[8246242]
NPT2192 Cell Line HEL Homo sapiens IC50 = 5.0 ug.mL-1 PMID[8246242]
NPT2192 Cell Line HEL Homo sapiens IC50 = 26.0 ug.mL-1 PMID[8246242]
NPT2192 Cell Line HEL Homo sapiens IC50 = 22.0 ug.mL-1 PMID[8246242]
NPT2192 Cell Line HEL Homo sapiens IC50 > 200.0 ug.mL-1 PMID[8246242]
NPT25 Cell Line MT4 Homo sapiens IC50 > 100.0 ug.mL-1 PMID[8246242]
NPT404 Cell Line CCRF-CEM Homo sapiens EC50 > 200000.0 nM PMID[14643328]
NPT404 Cell Line CCRF-CEM Homo sapiens CC50 > 200000.0 nM PMID[14643328]
NPT2192 Cell Line HEL Homo sapiens EC50 = 320.0 nM PMID[14643328]
NPT2192 Cell Line HEL Homo sapiens EC50 = 1300.0 nM PMID[14643328]
NPT2192 Cell Line HEL Homo sapiens EC50 = 88000.0 nM PMID[14643328]
NPT2192 Cell Line HEL Homo sapiens CC50 > 1700000.0 nM PMID[14643328]
NPT2215 Individual Protein DNA polymerase alpha subunit Homo sapiens Inhibition = 37.0 % PMID[3009816]
NPT2192 Cell Line HEL Homo sapiens IC50 = 0.23 ug.mL-1 DOI[10.1016/S0960-894X(01)80538-2]
NPT2192 Cell Line HEL Homo sapiens IC50 = 0.32 ug.mL-1 DOI[10.1016/S0960-894X(01)80538-2]
NPT2192 Cell Line HEL Homo sapiens IC50 = 22.0 ug.mL-1 DOI[10.1016/S0960-894X(01)80538-2]
NPT2192 Cell Line HEL Homo sapiens IC50 = 9.0 ug.mL-1 DOI[10.1016/S0960-894X(01)80538-2]
NPT2192 Cell Line HEL Homo sapiens CC50 > 50.0 ug.mL-1 DOI[10.1016/S0960-894X(01)80538-2]
NPT2192 Cell Line HEL Homo sapiens CC50 > 200.0 ug.mL-1 PMID[12217359]
NPT171 Cell Line MRC5 Homo sapiens CD50 = 355.0 uM PMID[8496903]
NPT189 Cell Line Vero Chlorocebus aethiops ID50 = 0.5 uM PMID[3871860]
NPT2192 Cell Line HEL Homo sapiens CC50 > 400000.0 nM PMID[10966745]
NPT2192 Cell Line HEL Homo sapiens CC50 = 200.0 ug.mL-1 PMID[15658861]
NPT165 Cell Line HeLa Homo sapiens CC50 > 400000.0 nM PMID[15993062]
NPT4951 Cell Line E6SM Homo sapiens EC50 = 0.07 ug.mL-1 PMID[15481985]
NPT2192 Cell Line HEL Homo sapiens EC50 > 200000.0 nM PMID[15481985]
NPT2192 Cell Line HEL Homo sapiens EC50 > 400000.0 nM PMID[15481985]
NPT4951 Cell Line E6SM Homo sapiens EC50 = 48.0 ug.mL-1 PMID[15481985]
NPT4951 Cell Line E6SM Homo sapiens EC50 = 0.38 ug.mL-1 PMID[15481985]
NPT2192 Cell Line HEL Homo sapiens EC50 = 1300.0 nM PMID[15481985]
NPT2192 Cell Line HEL Homo sapiens EC50 = 900.0 nM PMID[15481985]
NPT2192 Cell Line HEL Homo sapiens EC50 = 24000.0 nM PMID[15481985]
NPT2192 Cell Line HEL Homo sapiens EC50 = 27000.0 nM PMID[15481985]
NPT2192 Cell Line HEL Homo sapiens EC50 = 17000.0 nM PMID[15801851]
NPT2192 Cell Line HEL Homo sapiens EC50 = 20000.0 nM PMID[15801851]
NPT2192 Cell Line HEL Homo sapiens EC50 = 7100.0 nM PMID[15801851]
NPT2192 Cell Line HEL Homo sapiens EC50 = 111000.0 nM PMID[15801851]
NPT2192 Cell Line HEL Homo sapiens CC50 = 511000.0 nM PMID[15801851]
NPT859 Cell Line HFF Homo sapiens CC50 > 444000.0 nM PMID[15634003]
NPT189 Cell Line Vero Chlorocebus aethiops CC50 > 200000.0 nM PMID[15634003]
NPT464 Cell Line Daudi Homo sapiens CC50 > 222000.0 nM PMID[15634003]
NPT859 Cell Line HFF Homo sapiens IC50 > 20000.0 nM PMID[16134946]
NPT189 Cell Line Vero Chlorocebus aethiops IC50 > 10000.0 nM PMID[16134946]
NPT189 Cell Line Vero Chlorocebus aethiops IC50 = 5400.0 nM PMID[16134946]
NPT189 Cell Line Vero Chlorocebus aethiops IC50 = 2400.0 nM PMID[16134946]
NPT189 Cell Line Vero Chlorocebus aethiops IC50 = 2800.0 nM PMID[16134946]
NPT859 Cell Line HFF Homo sapiens IC50 = 8100.0 nM PMID[16134946]
NPT189 Cell Line Vero Chlorocebus aethiops IC50 = 2100.0 nM PMID[16134946]
NPT859 Cell Line HFF Homo sapiens CC50 > 100000.0 nM PMID[16134946]
NPT189 Cell Line Vero Chlorocebus aethiops CC50 > 100000.0 nM PMID[16134946]
NPT189 Cell Line Vero Chlorocebus aethiops IC50 = 3500.0 nM PMID[16134946]
NPT189 Cell Line Vero Chlorocebus aethiops IC50 = 4400.0 nM PMID[16134946]
NPT2192 Cell Line HEL Homo sapiens CC50 > 889000.0 nM PMID[16392824]
NPT2192 Cell Line HEL Homo sapiens CC50 = 118.0 ug.mL-1 PMID[16480257]
NPT189 Cell Line Vero Chlorocebus aethiops CC50 = 960000.0 nM PMID[16321530]
NPT91 Cell Line KB Homo sapiens CC50 > 100000.0 nM PMID[17004726]
NPT464 Cell Line Daudi Homo sapiens CC50 > 100000.0 nM PMID[17004726]
NPT2192 Cell Line HEL Homo sapiens CC50 > 500000.0 nM PMID[17181162]
NPT4951 Cell Line E6SM Homo sapiens MIC > 500000.0 nM PMID[17286431]
NPT2192 Cell Line HEL Homo sapiens Activity > 100.0 ug ml-1 PMID[17298047]
NPT2192 Cell Line HEL Homo sapiens Activity = 173.5 ug ml-1 PMID[17298047]
NPT859 Cell Line HFF Homo sapiens CC50 > 444000.0 nM PMID[15615545]
NPT464 Cell Line Daudi Homo sapiens CC50 > 222000.0 nM PMID[15615545]
NPT4951 Cell Line E6SM Homo sapiens MIC > 500000.0 nM PMID[17092728]
NPT189 Cell Line Vero Chlorocebus aethiops CC50 > 200000.0 nM PMID[17368024]
NPT2192 Cell Line HEL Homo sapiens CC50 = 649000.0 nM PMID[17539622]
NPT2192 Cell Line HEL Homo sapiens CC50 > 890000.0 nM PMID[17622128]
NPT2192 Cell Line HEL Homo sapiens CC50 = 545000.0 nM PMID[17672445]
NPT2192 Cell Line HEL Homo sapiens EC50 = 0.03 ug.mL-1 PMID[17948980]
NPT2192 Cell Line HEL Homo sapiens EC50 >= 25.2 ug.mL-1 PMID[17948980]
NPT2192 Cell Line HEL Homo sapiens CC50 = 212.0 ug.mL-1 PMID[17948980]
NPT2192 Cell Line HEL Homo sapiens CC50 > 200000.0 nM PMID[18052321]
NPT859 Cell Line HFF Homo sapiens CC50 > 100000.0 nM PMID[17434304]
NPT2192 Cell Line HEL Homo sapiens CC50 > 200.0 ug.mL-1 PMID[17869124]
NPT189 Cell Line Vero Chlorocebus aethiops CC50 = 126000.0 nM PMID[17937990]
NPT189 Cell Line Vero Chlorocebus aethiops CC50 > 200000.0 nM PMID[18086523]
NPT189 Cell Line Vero Chlorocebus aethiops CC50 > 100000.0 nM PMID[17981031]
NPT1763 Individual Protein Thymidine kinase Macacine herpesvirus 1 IC50 = 1000000.0 nM PMID[17438061]
NPT189 Cell Line Vero Chlorocebus aethiops CC50 > 890000.0 nM PMID[17438061]
NPT3788 Individual Protein Thymidine kinase Human herpesvirus 1 IC50 = 122000.0 nM PMID[17438061]
NPT189 Cell Line Vero Chlorocebus aethiops CC50 = 122000.0 ug.mL-1 PMID[11678658]
NPT189 Cell Line Vero Chlorocebus aethiops CC100 > 600.0 ug ml-1 PMID[11678658]
NPT2192 Cell Line HEL Homo sapiens CC50 = 200.0 ug.mL-1 PMID[17583388]
NPT189 Cell Line Vero Chlorocebus aethiops IC50 > 100.0 ug.mL-1 PMID[9214738]
NPT613 Individual Protein Solute carrier family 22 member 1 Homo sapiens Inhibition = -3.9 % PMID[18788725]
NPT189 Cell Line Vero Chlorocebus aethiops CC100 > 600.0 ug ml-1 PMID[11858754]
NPT2192 Cell Line HEL Homo sapiens CC50 = 137.0 ug.mL-1 PMID[18835175]
NPT189 Cell Line Vero Chlorocebus aethiops CC50 > 10.0 ug.mL-1 PMID[12444692]
NPT189 Cell Line Vero Chlorocebus aethiops CC50 > 500.0 ug.mL-1 PMID[16724853]
NPT2192 Cell Line HEL Homo sapiens CC50 = 1350000.0 nM PMID[18614365]
NPT859 Cell Line HFF Homo sapiens CC50 > 100000.0 nM PMID[18595689]
NPT2192 Cell Line HEL Homo sapiens CC50 = 733000.0 nM PMID[19226140]
NPT165 Cell Line HeLa Homo sapiens CC100 > 600.0 ug ml-1 PMID[19217699]
NPT859 Cell Line HFF Homo sapiens CC50 > 300000.0 nM PMID[19410465]
NPT404 Cell Line CCRF-CEM Homo sapiens IC50 > 250000.0 nM PMID[19645484]
NPT25 Cell Line MT4 Homo sapiens CC50 > 250000.0 nM PMID[19645484]
NPT25 Cell Line MT4 Homo sapiens IC50 > 250000.0 nM PMID[19645484]
NPT2192 Cell Line HEL Homo sapiens CC50 = 782000.0 nM PMID[19339082]
NPT25 Cell Line MT4 Homo sapiens CC50 > 100000.0 nM PMID[19482481]
NPT189 Cell Line Vero Chlorocebus aethiops CC50 > 100000.0 nM PMID[19482481]
NPT189 Cell Line Vero Chlorocebus aethiops CC50 > 200000.0 nM PMID[19700316]
NPT2192 Cell Line HEL Homo sapiens CC50 = 1778000.0 nM PMID[20064723]
NPT189 Cell Line Vero Chlorocebus aethiops CC100 > 600.0 ug ml-1 PMID[19892441]
NPT189 Cell Line Vero Chlorocebus aethiops CC50 > 100000.0 nM PMID[20359898]
NPT25 Cell Line MT4 Homo sapiens CC50 > 100000.0 nM PMID[20359898]
NPT859 Cell Line HFF Homo sapiens CC50 > 100000.0 nM PMID[20403696]
NPT4896 Individual Protein Purine nucleoside phosphorylase Mycobacterium tuberculosis Kd = 12589.25 nM PMID[20570524]
NPT859 Cell Line HFF Homo sapiens CC50 > 444000.0 nM PMID[19770274]
NPT859 Cell Line HFF Homo sapiens IC50 > 444000.0 nM PMID[19770274]
NPT2192 Cell Line HEL Homo sapiens CC50 > 130000.0 nM PMID[21232828]
NPT189 Cell Line Vero Chlorocebus aethiops CC50 = 860000.0 nM PMID[21376603]
NPT189 Cell Line Vero Chlorocebus aethiops CC50 > 200000.0 nM PMID[21334891]
NPT2454 Cell Line RD Homo sapiens CC50 > 25000.0 nM PMID[21356589]
NPT859 Cell Line HFF Homo sapiens CC50 > 100000.0 nM PMID[21376429]
NPT2192 Cell Line HEL Homo sapiens CC50 = 1338000.0 nM PMID[21745746]
NPT2192 Cell Line HEL Homo sapiens CC50 > 400000.0 nM PMID[21696963]
NPT2192 Cell Line HEL Homo sapiens CC50 = 1421000.0 nM PMID[21565516]
NPT189 Cell Line Vero Chlorocebus aethiops CC50 > 100000.0 nM PMID[22047799]
NPT165 Cell Line HeLa Homo sapiens CC50 = 541000.0 nM PMID[22459876]
NPT2192 Cell Line HEL Homo sapiens CC50 = 470000.0 nM PMID[22578783]
NPT189 Cell Line Vero Chlorocebus aethiops CC50 > 100000.0 nM PMID[22513121]
NPT859 Cell Line HFF Homo sapiens CC50 > 300000.0 nM PMID[22607883]
NPT2192 Cell Line HEL Homo sapiens CC50 = 918000.0 nM PMID[22858222]
NPT613 Individual Protein Solute carrier family 22 member 1 Homo sapiens Activity = 88.4 % PMID[11861798]
NPT189 Cell Line Vero Chlorocebus aethiops CC50 = 130.0 ug.mL-1 PMID[22921079]
NPT189 Cell Line Vero Chlorocebus aethiops CC50 > 2000000.0 nM PMID[22954898]
NPT2192 Cell Line HEL Homo sapiens CC50 = 134000.0 nM PMID[23047229]
NPT189 Cell Line Vero Chlorocebus aethiops CC50 > 200000.0 nM PMID[22704890]
NPT622 Individual Protein Solute carrier organic anion transporter family member 2B1 Homo sapiens Inhibition = -15.2 % PMID[22541068]
NPT189 Cell Line Vero Chlorocebus aethiops CC50 > 200000.0 nM PMID[23141915]
NPT189 Cell Line Vero Chlorocebus aethiops CC50 = 1275.0 ug.mL-1 DOI[10.1007/s00044-011-9574-8]
NPT189 Cell Line Vero Chlorocebus aethiops CC50 = 960000.0 nM DOI[10.1007/s00044-007-9035-6]
NPT2192 Cell Line HEL Homo sapiens CC50 = 120.0 ug.mL-1 DOI[10.1007/s00044-011-9776-0]
NPT189 Cell Line Vero Chlorocebus aethiops CC50 > 50000.0 nM PMID[23419738]
NPT25 Cell Line MT4 Homo sapiens CC50 > 250000.0 nM PMID[24177359]
NPT2192 Cell Line HEL Homo sapiens CC50 = 440000.0 nM PMID[24690527]
NPT1306 Cell Line WISH Homo sapiens Activity = 3414.0 umol/L PMID[25515560]
NPT25 Cell Line MT4 Homo sapiens CC50 > 100000.0 nM PMID[25082514]
NPT1463 Individual Protein Cytochrome P450 2J2 Homo sapiens IC50 > 50000.0 nM PMID[23033255]
NPT2773 Individual Protein Solute carrier family 22 member 7 Homo sapiens FC = 10.0 n.a. PMID[22190696]
NPT6179 Individual Protein POU domain, class 2, transcription factor 2 Homo sapiens Ratio = 6.0 uL/min PMID[22190696]
NPT189 Cell Line Vero Chlorocebus aethiops CC50 > 1000000.0 nM PMID[26048809]
NPT2192 Cell Line HEL Homo sapiens CC50 > 440000.0 nM PMID[26443550]
NPT25 Cell Line MT4 Homo sapiens CC50 > 100000.0 nM PMID[26443549]
NPT189 Cell Line Vero Chlorocebus aethiops IC50 > 1700000.0 nM PMID[26638041]
NPT2192 Cell Line HEL Homo sapiens CC50 = 440000.0 nM PMID[27750154]
NPT189 Cell Line Vero Chlorocebus aethiops TC50 > 100.0 umol/L PMID[27792321]
NPT189 Cell Line Vero Chlorocebus aethiops CC50 > 1000000.0 nM PMID[28129981]
NPT2192 Cell Line HEL Homo sapiens CC50 = 787000.0 nM PMID[28829913]
NPT612 Individual Protein Canalicular multispecific organic anion transporter 1 Homo sapiens IC50 > 133000.0 nM PMID[23956101]
NPT1249 Individual Protein Canalicular multispecific organic anion transporter 2 Homo sapiens IC50 > 133000.0 nM PMID[23956101]
NPT1028 Individual Protein Multidrug resistance-associated protein 4 Homo sapiens IC50 > 133000.0 nM PMID[23956101]
NPT2192 Cell Line HEL Homo sapiens CC50 > 444000.0 nM PMID[28682067]
NPT2192 Cell Line HEL Homo sapiens CC50 > 440000.0 nM PMID[28757102]
NPT189 Cell Line Vero Chlorocebus aethiops CC50 > 200000.0 nM PMID[29099182]
NPT2192 Cell Line HEL Homo sapiens CC50 > 440000.0 nM PMID[29945100]
NPT2192 Cell Line HEL Homo sapiens CC50 > 440000.0 nM PMID[29407990]
NPT189 Cell Line Vero Chlorocebus aethiops TC50 > 100.0 uM PMID[30106288]
NPT2192 Cell Line HEL Homo sapiens CC50 > 444000.0 nM PMID[29550734]
NPT2192 Cell Line HEL Homo sapiens CC50 > 444000.0 nM PMID[29268134]
NPT2192 Cell Line HEL Homo sapiens CC50 > 444000.0 nM PMID[29670705]
NPT1291 Individual Protein Purine nucleoside phosphorylase Homo sapiens Ki = 91000.0 nM PMID[30627387]
NPT189 Cell Line Vero Chlorocebus aethiops CC50 > 2000000.0 nM PMID[30798081]
NPT109 Individual Protein Cytochrome P450 3A4 Homo sapiens FC = 1.0 n.a. PMID[27397500]
NPT110 Individual Protein Cytochrome P450 2D6 Homo sapiens FC = 1.0 n.a. PMID[27397500]
NPT212 Individual Protein Cytochrome P450 2C9 Homo sapiens FC = 1.0 n.a. PMID[27397500]
NPT71 Cell Line HEK293 Homo sapiens CC50 > 20000.0 nM DOI[10.6019/CHEMBL4296181]
NPT2192 Cell Line HEL Homo sapiens CC50 > 444000.0 nM PMID[32676147]
NPT189 Cell Line Vero Chlorocebus aethiops CC50 = 1100000.0 ug.mL-1 PMID[32089391]
NPT2192 Cell Line HEL Homo sapiens CC50 = 424000.0 nM PMID[33479570]
NPT859 Cell Line HFF Homo sapiens CC50 > 300000.0 nM PMID[27933957]
NPT2192 Cell Line HEL Homo sapiens CC50 > 300000.0 nM PMID[33039724]
NPT2 Others Unspecified Inhibition = 40.0 % PMID[2848125]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. ED50 = 3.0 ug ml-1 PMID[2848125]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 IC50 = 4800.0 nM PMID[1846922]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 IC50 = 1200.0 nM PMID[1846922]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 IC50 = 15000.0 nM PMID[1846922]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 Inhibition = 100.0 % PMID[7932528]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 Inhibition = 0.0 % PMID[7932528]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 MIC = 0.82 ug.mL-1 PMID[8709116]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 MIC = 0.95 ug.mL-1 PMID[8709116]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 MIC = 25.0 ug.mL-1 PMID[8709116]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 MIC = 40.0 ug.mL-1 PMID[8709116]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 ID50 = 0.4 uM PMID[2993615]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 ID50 = 1.5 uM PMID[2993615]
NPT1750 Organism Human herpesvirus 5 Human herpesvirus 5 ID50 = 100.0 uM PMID[2993615]
NPT419 Organism Oryctolagus cuniculus Oryctolagus cuniculus MIC = 0.08 ug.mL-1 PMID[6300403]
NPT419 Organism Oryctolagus cuniculus Oryctolagus cuniculus MIC = 0.1 ug.mL-1 PMID[6300403]
NPT419 Organism Oryctolagus cuniculus Oryctolagus cuniculus MIC = 0.09 ug.mL-1 PMID[6300403]
NPT419 Organism Oryctolagus cuniculus Oryctolagus cuniculus MIC = 0.04 ug.mL-1 PMID[6300403]
NPT419 Organism Oryctolagus cuniculus Oryctolagus cuniculus MIC = 0.06 ug.mL-1 PMID[6300403]
NPT419 Organism Oryctolagus cuniculus Oryctolagus cuniculus MIC = 80.0 ug.mL-1 PMID[6300403]
NPT419 Organism Oryctolagus cuniculus Oryctolagus cuniculus MIC > 400.0 ug.mL-1 PMID[6300403]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 ED50 = 0.5 uM PMID[14584951]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 ED50 = 2.5 uM PMID[14584951]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 IC50 > 100.0 ug.mL-1 PMID[2838633]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 IC50 = 2.6 ug.mL-1 PMID[2838633]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 Therapeutic index > 38.0 n.a. PMID[2838633]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 MIC = 1.563 ug.mL-1 DOI[10.1016/S0960-894X(97)00365-X]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 MIC = 6.25 ug.mL-1 DOI[10.1016/S0960-894X(97)00365-X]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 ED50 = 0.14 ug ml-1 PMID[9216836]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 ED50 = 0.23 ug ml-1 PMID[9216836]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 ED50 = 2.7 ug ml-1 PMID[9216836]
NPT1750 Organism Human herpesvirus 5 Human herpesvirus 5 ED50 = 6.9 ug ml-1 PMID[9216836]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 ID50 = 0.48 uM PMID[2828623]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 ID50 = 1.6 uM PMID[2828623]
NPT27 Others Unspecified ID50 = 360.0 uM PMID[2828623]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 ED50 = 0.02 ug ml-1 PMID[2213836]
NPT334 Organism Vaccinia virus Vaccinia virus ED50 > 110.0 ug ml-1 PMID[2213836]
NPT1748 Organism African swine fever virus African swine fever virus ED50 = 40.0 ug ml-1 PMID[2213836]
NPT195 Organism Vesicular stomatitis virus Vesicular stomatitis virus ED50 > 40.0 ug ml-1 PMID[2213836]
NPT317 Uncleic Acid Nucleic Acid EC50 = 6750.0 nM PMID[12408726]
NPT26641 CELL-LINE P3HR-1 Homo sapiens CC50 = 392000.0 nM PMID[12408726]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. MIC = 0.02 ug.mL-1 PMID[7932543]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 MIC = 0.004 ug.mL-1 PMID[7932543]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. MIC = 0.07 ug.mL-1 PMID[7932543]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. MIC = 0.09 ug.mL-1 PMID[7932543]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. MIC = 0.01 ug.mL-1 PMID[7932543]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. MIC = 0.009 ug.mL-1 PMID[7932543]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 MIC = 5.0 ug.mL-1 PMID[7932543]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 MIC = 70.0 ug.mL-1 PMID[7932543]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 MIC = 0.38 ug.mL-1 PMID[7932543]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 MIC = 0.18 ug.mL-1 PMID[7932543]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 MIC = 4.7 ug.mL-1 PMID[7932543]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 MIC = 13.7 ug.mL-1 PMID[7932543]
NPT1750 Organism Human herpesvirus 5 Human herpesvirus 5 MIC = 13.2 ug.mL-1 PMID[7932543]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 MIC > 220.0 ug.mL-1 PMID[7932543]
NPT334 Organism Vaccinia virus Vaccinia virus MIC > 180.0 ug.mL-1 PMID[7932543]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 ED50 = 0.08 ug ml-1 PMID[2329551]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 ED50 = 0.09 ug ml-1 PMID[2329551]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 ED50 = 0.1 ug ml-1 PMID[2329551]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 ED50 = 0.07 ug ml-1 PMID[2329551]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 ED50 = 0.06 ug ml-1 PMID[2329551]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 ED50 = 2.3 ug ml-1 PMID[2329551]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 ED50 = 3.7 ug ml-1 PMID[2329551]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 ID50 > 100.0 ug ml-1 PMID[2329551]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 ID50 > 100.0 ug ml-1 PMID[2329551]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. ID50 > 100.0 ug ml-1 PMID[2329551]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 ID50 > 100.0 ug ml-1 PMID[2329551]
NPT605 Organism Homo sapiens Homo sapiens ID50 = 165.0 ug ml-1 PMID[2329551]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 ED50 = 189.9 ug ml-1 PMID[2329551]
NPT27 Others Unspecified MIC = 0.07 ug.mL-1 PMID[8176708]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 MIC = 100.0 ug.mL-1 PMID[8176708]
NPT334 Organism Vaccinia virus Vaccinia virus MIC > 400.0 ug.mL-1 PMID[8176708]
NPT195 Organism Vesicular stomatitis virus Vesicular stomatitis virus MIC > 400.0 ug.mL-1 PMID[8176708]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 MIC = 0.004 ug.mL-1 DOI[10.1016/S0960-894X(96)00244-2]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 MIC = 0.004 ug.mL-1 DOI[10.1016/S0960-894X(96)00244-2]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 MIC = 0.5 ug.mL-1 DOI[10.1016/S0960-894X(96)00244-2]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 IC50 = 0.01 ug.mL-1 PMID[11412988]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 IC50 = 9.6 ug.mL-1 PMID[11412988]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 IC50 = 0.02 ug.mL-1 PMID[11412988]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 IC50 = 1.1 ug.mL-1 PMID[11412988]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 IC50 = 13.0 ug.mL-1 PMID[11412988]
NPT963 Organism Hepatitis B virus Hepatitis B virus IC50 > 50.0 ug.mL-1 PMID[11412988]
NPT3148 Organism Cytomegalovirus Cytomegalovirus EC50 = 16.0 ug.mL-1 PMID[11412988]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 2900.0 nM PMID[10579812]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 1000.0 nM PMID[10579812]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 74000.0 nM PMID[10579812]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 125000.0 nM PMID[10579812]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 2220.0 nM PMID[14584954]
NPT605 Organism Homo sapiens Homo sapiens EC50 = 10210.0 nM PMID[14584954]
NPT605 Organism Homo sapiens Homo sapiens EC50 = 1100.0 nM PMID[14584954]
NPT605 Organism Homo sapiens Homo sapiens EC50 = 1680.0 nM PMID[14584954]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 1.054 ug.mL-1 PMID[9871553]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 EC50 = 5.12 ug.mL-1 PMID[9871553]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. IC50 = 250.0 ug.mL-1 PMID[9871553]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 ID50 = 0.5 ug ml-1 PMID[2157012]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 ID50 = 2.4 ug ml-1 PMID[2157012]
NPT1750 Organism Human herpesvirus 5 Human herpesvirus 5 ID50 = 38.4 ug ml-1 PMID[2157012]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 1500.0 nM PMID[15109620]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 1100.0 nM PMID[15109620]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 40000.0 nM PMID[15109620]
NPT3148 Organism Cytomegalovirus Cytomegalovirus IC50 = 63000.0 nM PMID[2840500]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 IC50 = 2600.0 nM PMID[2840500]
NPT27 Others Unspecified IC50 > 100000.0 nM PMID[2840500]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 MIC = 0.02 ug.mL-1 PMID[8393114]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 MIC = 0.4 ug.mL-1 PMID[8393114]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 MIC = 0.7 ug.mL-1 PMID[8393114]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 MIC = 0.02 ug.mL-1 PMID[8393114]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 MIC = 2.0 ug.mL-1 PMID[8393114]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 MIC = 0.7 ug.mL-1 PMID[8393114]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 MIC = 70.0 ug.mL-1 PMID[8393114]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 MIC = 0.15 ug.mL-1 PMID[8393114]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 MIC = 0.04 ug.mL-1 PMID[8393114]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 MIC = 5.0 ug.mL-1 PMID[8393114]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 MIC = 3.0 ug.mL-1 PMID[8393114]
NPT195 Organism Vesicular stomatitis virus Vesicular stomatitis virus MIC > 400.0 ug.mL-1 PMID[8393114]
NPT334 Organism Vaccinia virus Vaccinia virus MIC > 400.0 ug.mL-1 PMID[8393114]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 2000.0 nM PMID[10891113]
NPT164 Organism Human herpesvirus 4 Human herpesvirus 4 EC50 = 19700.0 nM PMID[10891113]
NPT27 Others Unspecified EC50 = 13600.0 nM PMID[10891113]
NPT27 Others Unspecified Therapeutic index > 3.8 n.a. PMID[1316966]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 ID50 = 0.2 ug ml-1 PMID[1848298]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 ID50 = 0.6 ug ml-1 PMID[1848298]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 ED50 = 58.0 mg.kg-1 PMID[1848298]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 ED50 = 58.0 mg.kg-1 PMID[1848298]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 ED50 ~ 50.0 mg.kg-1 PMID[1848298]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 1000.0 nM PMID[10866384]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 2900.0 nM PMID[10866384]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 74000.0 nM PMID[10866384]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 125000.0 nM PMID[10866384]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 Inhibition = 85.0 % PMID[2989523]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 Inhibition = 34.0 % PMID[2989523]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 ED50 = 1.0 ug ml-1 PMID[2989523]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 ED50 = 1.0 ug ml-1 PMID[2989523]
NPT1750 Organism Human herpesvirus 5 Human herpesvirus 5 ED50 = 20.0 ug ml-1 PMID[2989523]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 ED50 = 1.0 ug ml-1 PMID[2989523]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 23000.0 nM PMID[10999490]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 EC50 = 35000.0 nM PMID[10999490]
NPT1750 Organism Human herpesvirus 5 Human herpesvirus 5 IC50 = 63000.0 nM PMID[2163453]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 IC50 = 3900.0 nM PMID[2163453]
NPT27 Others Unspecified IC50 > 100000.0 nM PMID[2163453]
NPT1750 Organism Human herpesvirus 5 Human herpesvirus 5 IC50 = 63000.0 nM PMID[2175356]
NPT1750 Organism Human herpesvirus 5 Human herpesvirus 5 IC90 = 90000.0 nM PMID[2175356]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 IC50 = 4000.0 nM PMID[2175356]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 IC90 = 7000.0 nM PMID[2175356]
NPT27 Others Unspecified IC50 > 100000.0 nM PMID[2175356]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 MIC = 0.2 ug.mL-1 PMID[2455050]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 MIC = 0.1 ug.mL-1 PMID[2455050]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 MIC = 0.07 ug.mL-1 PMID[2455050]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 MIC = 0.2 ug.mL-1 PMID[2455050]
NPT334 Organism Vaccinia virus Vaccinia virus MIC = 150.0 ug.mL-1 PMID[2455050]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 MIC = 20.0 ug.mL-1 PMID[2455050]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 MIC = 0.3 ug.mL-1 PMID[2455050]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 MIC = 0.6 ug.mL-1 PMID[2455050]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 MIC = 25.0 ug.mL-1 PMID[2455050]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 MIC = 10.0 ug.mL-1 PMID[2455050]
NPT3148 Organism Cytomegalovirus Cytomegalovirus MIC = 20.0 ug.mL-1 PMID[2455050]
NPT3148 Organism Cytomegalovirus Cytomegalovirus MIC = 25.0 ug.mL-1 PMID[2455050]
NPT18622 ORGANISM Suid herpesvirus 1 Suid herpesvirus 1 MIC = 7.0 ug.mL-1 PMID[2455050]
NPT19357 ORGANISM Bovine herpesvirus 1 Bovine herpesvirus 1 MIC = 7.0 ug.mL-1 PMID[2455050]
NPT19358 ORGANISM Equid herpesvirus 1 Equid herpesvirus 1 MIC = 0.2 ug.mL-1 PMID[2455050]
NPT27 Others Unspecified MIC = 8.0 ug.mL-1 PMID[2455050]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 ID50 = 0.5 ug ml-1 PMID[2544723]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 ID50 = 4.3 ug ml-1 PMID[2544723]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 ID50 = 0.3 ug ml-1 PMID[2544723]
NPT32 Organism Mus musculus Mus musculus Survival = 75.0 % PMID[2544723]
NPT32 Organism Mus musculus Mus musculus Survival = 70.0 % PMID[2544723]
NPT32 Organism Mus musculus Mus musculus Survival = 50.0 % PMID[2544723]
NPT32 Organism Mus musculus Mus musculus Survival = 2.0 % PMID[2544723]
NPT32 Organism Mus musculus Mus musculus Survival = 78.0 % PMID[2544723]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 ID50 = 0.7 ug ml-1 PMID[3411597]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 ID50 = 5.3 ug ml-1 PMID[3411597]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 MIC = 10.0 nM PMID[2842506]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 MIC = 4400.0 nM PMID[2842506]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 MIC = 1300.0 nM PMID[2842506]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 MIC = 13200.0 nM PMID[2842506]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 MIC = 44000.0 nM PMID[2842506]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 MIC = 440000.0 nM PMID[2842506]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 MIC = 132000.0 nM PMID[2842506]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 MIC = 440000.0 nM PMID[2842506]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 MIC50 = 3.0 ug.mL-1 PMID[3035178]
NPT2 Others Unspecified Ratio = 0.33 n.a. PMID[3035178]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 IC50 = 0.73 ug.mL-1 PMID[10197958]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 IC50 = 0.78 ug.mL-1 PMID[10197958]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 IC50 = 24.0 ug.mL-1 PMID[10197958]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 IC50 = 26.0 ug.mL-1 PMID[10197958]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 0.06 ug.mL-1 DOI[10.1016/S0960-894X(97)00082-6]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 0.3 ug.mL-1 DOI[10.1016/S0960-894X(97)00082-6]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 EC50 = 0.2 ug.mL-1 DOI[10.1016/S0960-894X(97)00082-6]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 EC50 = 1.1 ug.mL-1 DOI[10.1016/S0960-894X(97)00082-6]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 0.6 ug.mL-1 DOI[10.1016/S0960-894X(97)00082-6]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 ID50 = 0.05 ug ml-1 PMID[6092636]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 ID50 = 0.04 ug ml-1 PMID[6092636]
NPT334 Organism Vaccinia virus Vaccinia virus ID50 = 50.0 ug ml-1 PMID[6092636]
NPT195 Organism Vesicular stomatitis virus Vesicular stomatitis virus ID50 > 400.0 ug ml-1 PMID[6092636]
NPT27 Others Unspecified ID50 = 12.0 ug ml-1 PMID[6092636]
NPT27 Others Unspecified ID50 = 13.0 ug ml-1 PMID[6092636]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 3080.0 nM PMID[11814776]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 EC50 = 6160.0 nM PMID[11814776]
NPT164 Organism Human herpesvirus 4 Human herpesvirus 4 EC50 = 3960.0 nM PMID[11814776]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 8810.0 nM PMID[11814776]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 2900.0 nM PMID[11212118]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 1000.0 nM PMID[11212118]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 > 4000.0 nM PMID[11212118]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 125000.0 nM PMID[11212118]
NPT1750 Organism Human herpesvirus 5 Human herpesvirus 5 IC50 = 63000.0 nM PMID[2163454]
NPT1750 Organism Human herpesvirus 5 Human herpesvirus 5 IC50 = 90000.0 nM PMID[2163454]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 IC50 = 4000.0 nM PMID[2163454]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 IC50 = 7000.0 nM PMID[2163454]
NPT27 Others Unspecified IC50 > 100000.0 nM PMID[2163454]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 ID50 = 1.3 uM PMID[2521518]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 ID50 = 2.2 uM PMID[2521518]
NPT27 Others Unspecified EC50 = 0.077 ug.mL-1 PMID[12459010]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 0.077 ug.mL-1 PMID[12459010]
NPT27 Others Unspecified EC50 = 0.384 ug.mL-1 PMID[12459010]
NPT2 Others Unspecified EC50 = 0.384 ug.mL-1 PMID[12459010]
NPT334 Organism Vaccinia virus Vaccinia virus EC50 > 400.0 ug.mL-1 PMID[12459010]
NPT195 Organism Vesicular stomatitis virus Vesicular stomatitis virus EC50 > 400.0 ug.mL-1 PMID[12459010]
NPT27 Others Unspecified EC50 = 48.0 ug.mL-1 PMID[12459010]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. MIC = 341.0 nM PMID[12408716]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. MIC = 242.0 nM PMID[12408716]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. MIC = 1000.0 nM PMID[12408716]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. MIC = 249000.0 nM PMID[12408716]
NPT32 Organism Mus musculus Mus musculus Survival = 86.0 % PMID[1648622]
NPT32 Organism Mus musculus Mus musculus Survival = 70.0 % PMID[1648622]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 IC50 = 0.82 ug.mL-1 PMID[9836626]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 IC50 = 0.95 ug.mL-1 PMID[9836626]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 IC50 > 25.0 ug.mL-1 PMID[9836626]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 IC50 > 40.0 ug.mL-1 PMID[9836626]
NPT1750 Organism Human herpesvirus 5 Human herpesvirus 5 IC50 = 63000.0 nM PMID[2846837]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 IC50 = 2600.0 nM PMID[2846837]
NPT27 Others Unspecified IC50 > 100000.0 nM PMID[2846837]
NPT27 Others Unspecified Inhibition > 100.0 % PMID[2846837]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 0.13 ug.mL-1 PMID[12161143]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 EC50 = 0.88 ug.mL-1 PMID[12161143]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 2900.0 nM PMID[11150169]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 1000.0 nM PMID[11150169]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 74000.0 nM PMID[11150169]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 125000.0 nM PMID[11150169]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 CC50 > 200000.0 nM PMID[11150169]
NPT27 Others Unspecified MIC = 0.2 ug.mL-1 PMID[2391680]
NPT27 Others Unspecified MIC = 0.1 ug.mL-1 PMID[2391680]
NPT27 Others Unspecified MIC = 0.02 ug.mL-1 PMID[2391680]
NPT27 Others Unspecified MIC = 0.07 ug.mL-1 PMID[2391680]
NPT27 Others Unspecified MIC = 150.0 ug.mL-1 PMID[2391680]
NPT27 Others Unspecified MIC > 400.0 ug.mL-1 PMID[2391680]
NPT27 Others Unspecified MIC = 20.0 ug.mL-1 PMID[2391680]
NPT27 Others Unspecified MIC = 10.0 ug.mL-1 PMID[2391680]
NPT32 Organism Mus musculus Mus musculus Activity = 17.2 n.a. PMID[2391680]
NPT32 Organism Mus musculus Mus musculus Activity = 40.8 n.a. PMID[2391680]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 EC50 = 10210.0 nM PMID[14584954]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 2400.0 nM PMID[14584954]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 30000.0 nM PMID[14584954]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 19000.0 nM PMID[14584954]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 CC50 = 488000.0 nM PMID[14584954]
NPT27 Others Unspecified LD50 = 1250.0 mg.kg-1 PMID[3950905]
NPT1750 Organism Human herpesvirus 5 Human herpesvirus 5 IC50 = 63000.0 nM PMID[2500527]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 IC50 = 3900.0 nM PMID[2500527]
NPT605 Organism Homo sapiens Homo sapiens IC50 > 100000.0 nM PMID[2500527]
NPT27 Others Unspecified IC50 > 100000.0 nM PMID[2500527]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 IC50 = 1800.0 nM PMID[8576922]
NPT27 Others Unspecified IC50 = 1700.0 nM PMID[8576922]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 IC50 = 46800.0 nM PMID[8576922]
NPT1750 Organism Human herpesvirus 5 Human herpesvirus 5 IC50 > 85000.0 nM PMID[8576922]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 ED50 = 12.3 ug ml-1 PMID[3027333]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 ED50 = 4.8 ug ml-1 PMID[3027333]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 ED50 = 0.2 uM DOI[10.1016/S0960-894X(00)80318-2]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 ED50 = 0.4 uM DOI[10.1016/S0960-894X(00)80318-2]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 ED50 = 2.0 uM DOI[10.1016/S0960-894X(00)80318-2]
NPT1750 Organism Human herpesvirus 5 Human herpesvirus 5 ED50 = 20.0 uM DOI[10.1016/S0960-894X(00)80318-2]
NPT1750 Organism Human herpesvirus 5 Human herpesvirus 5 IC50 = 63000.0 nM PMID[2913300]
NPT27 Others Unspecified IC50 = 2600.0 nM PMID[2913300]
NPT27 Others Unspecified IC50 > 100000.0 nM PMID[2913300]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 ID50 = 0.9 uM PMID[8387600]
NPT27 Others Unspecified ID50 = 2.0 uM PMID[8387600]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 ID50 > 440.0 uM PMID[8387600]
NPT27 Others Unspecified ID50 = 0.9 uM PMID[8387600]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 ID50 > 440.0 uM PMID[8387600]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 ID50 = 4.0 uM PMID[8387600]
NPT1750 Organism Human herpesvirus 5 Human herpesvirus 5 ID50 = 40.0 uM PMID[8387600]
NPT334 Organism Vaccinia virus Vaccinia virus ID50 > 440.0 uM PMID[8387600]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 ID50 = 2.0 uM PMID[8387600]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 ID50 = 100.0 uM PMID[8387600]
NPT19361 ORGANISM Cercopithecine herpesvirus 9 Cercopithecine herpesvirus 9 ID50 = 100.0 uM PMID[8387600]
NPT19362 CELL-LINE NC-37 Homo sapiens EC50 = 0.17 ug.mL-1 DOI[10.1016/S0960-894X(01)80146-3]
NPT19362 CELL-LINE NC-37 Homo sapiens CC50 > 100.0 ug.mL-1 DOI[10.1016/S0960-894X(01)80146-3]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. IC50 = 0.015 ug.mL-1 PMID[8831773]
NPT27 Others Unspecified IC50 = 0.02 ug.mL-1 PMID[8831773]
NPT1750 Organism Human herpesvirus 5 Human herpesvirus 5 IC50 = 13.0 ug.mL-1 PMID[8831773]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 IC50 = 0.18 ug.mL-1 PMID[8831773]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 IC50 = 0.35 ug.mL-1 PMID[8831773]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 IC50 = 11.0 ug.mL-1 PMID[8831773]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 IC50 = 22.0 ug.mL-1 PMID[8831773]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. IC50 = 0.81 ug.mL-1 PMID[10649983]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 MIC = 0.3 ug.mL-1 PMID[4067994]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 MIC = 3.0 ug.mL-1 PMID[4067994]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 MIC = 1.3 ug.mL-1 PMID[8388470]
NPT1750 Organism Human herpesvirus 5 Human herpesvirus 5 IC50 > 100000.0 nM PMID[8784444]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 IC50 = 3400.0 nM PMID[8784444]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 IC50 = 400.0 nM DOI[10.1016/S0960-894X(00)80317-0]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 IC50 = 400.0 nM DOI[10.1016/S0960-894X(00)80317-0]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 IC50 = 2000.0 nM DOI[10.1016/S0960-894X(00)80317-0]
NPT1750 Organism Human herpesvirus 5 Human herpesvirus 5 IC50 = 20000.0 nM DOI[10.1016/S0960-894X(00)80317-0]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 ID50 = 0.8 ug ml-1 PMID[6292425]
NPT605 Organism Homo sapiens Homo sapiens IC50 > 440000.0 nM PMID[8394933]
NPT605 Organism Homo sapiens Homo sapiens EC50 = 40.0 nM PMID[8394933]
NPT605 Organism Homo sapiens Homo sapiens EC50 = 90.0 nM PMID[8394933]
NPT605 Organism Homo sapiens Homo sapiens EC50 = 7100.0 nM PMID[8394933]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 MIC = 0.13 ug.mL-1 PMID[11708929]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 MIC = 0.08 ug.mL-1 PMID[11708929]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 MIC = 0.19 ug.mL-1 PMID[11708929]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 MIC = 0.07 ug.mL-1 PMID[11708929]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 MIC = 0.28 ug.mL-1 PMID[11708929]
NPT334 Organism Vaccinia virus Vaccinia virus MIC > 80.0 ug.mL-1 PMID[11708929]
NPT195 Organism Vesicular stomatitis virus Vesicular stomatitis virus MIC > 80.0 ug.mL-1 PMID[11708929]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 MIC = 19.0 ug.mL-1 PMID[11708929]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 MIC = 7.1 ug.mL-1 PMID[11708929]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. MIC > 400.0 ug.mL-1 DOI[10.1016/S0960-894X(96)00254-5]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 MIC = 0.02 ug.mL-1 DOI[10.1016/S0960-894X(96)00254-5]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 MIC = 0.03 ug.mL-1 DOI[10.1016/S0960-894X(96)00254-5]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 MIC = 80.0 ug.mL-1 DOI[10.1016/S0960-894X(96)00254-5]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 MIC = 4.0 ug.mL-1 DOI[10.1016/S0960-894X(96)00254-5]
NPT1750 Organism Human herpesvirus 5 Human herpesvirus 5 IC50 = 86000.0 nM PMID[8071942]
NPT1750 Organism Human herpesvirus 5 Human herpesvirus 5 IC90 = 85000.0 nM PMID[8071942]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 IC50 = 1700.0 nM PMID[8071942]
NPT1750 Organism Human herpesvirus 5 Human herpesvirus 5 IC50 > 100000.0 nM PMID[8071942]
NPT1750 Organism Human herpesvirus 5 Human herpesvirus 5 IC50 = 63000.0 nM PMID[1310744]
NPT1750 Organism Human herpesvirus 5 Human herpesvirus 5 IC90 = 90000.0 nM PMID[1310744]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 IC50 = 3400.0 nM PMID[1310744]
NPT27 Others Unspecified IC50 > 100000.0 nM PMID[1310744]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 2600.0 nM PMID[11708924]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 117600.0 nM PMID[11585457]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 2200.0 nM PMID[11585457]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 4400.0 nM PMID[11585457]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 EC50 = 6200.0 nM PMID[11585457]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 2600.0 nM PMID[11585457]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 Inhibition = 86.0 % PMID[3009816]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 160.0 nM PMID[10091689]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 CC50 > 100000.0 nM PMID[10091689]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 360.0 nM PMID[10425099]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 IC50 > 350000.0 nM PMID[10425099]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 EC50 = 1100.0 nM PMID[10425099]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 IC50 > 350000.0 nM PMID[10425099]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 IC50 = 200.0 nM DOI[10.1016/S0960-894X(97)00117-0]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 IC50 = 2100.0 nM DOI[10.1016/S0960-894X(97)00117-0]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 IC50 = 0.38 ug.mL-1 PMID[12217359]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 IC50 = 0.35 ug.mL-1 PMID[12217359]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 IC50 = 6.5 ug.mL-1 PMID[12217359]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 IC50 = 3.1 ug.mL-1 PMID[12217359]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 IC50 = 3900.0 nM PMID[8496903]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 IC50 = 4300.0 nM PMID[8496903]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 IC50 = 21000.0 nM PMID[8496903]
NPT3148 Organism Cytomegalovirus Cytomegalovirus IC50 = 93000.0 nM PMID[8496903]
NPT27 Others Unspecified MIC = 0.01 ug.mL-1 PMID[10691698]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 MIC = 0.003 ug.mL-1 PMID[10691698]
NPT27 Others Unspecified MIC = 0.005 ug.mL-1 PMID[10691698]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 MIC = 0.02 ug.mL-1 PMID[10691698]
NPT27 Others Unspecified MIC = 0.02 ug.mL-1 PMID[10691698]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. MIC = 0.02 ug.mL-1 PMID[10691698]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. MIC = 9.6 ug.mL-1 PMID[10691698]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. MIC = 0.07 ug.mL-1 PMID[10691698]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. MIC = 1.1 ug.mL-1 PMID[10691698]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 MIC = 0.8 ug.mL-1 PMID[10691698]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 MIC = 13.0 ug.mL-1 PMID[10691698]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 MIC = 28.0 ug.mL-1 PMID[10691698]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 IC50 = 4530.0 nM PMID[10966745]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 IC50 = 4090.0 nM PMID[10966745]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 IC50 = 41000.0 nM PMID[10966745]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 IC50 = 63000.0 nM PMID[10966745]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 IC50 = 100.0 nM PMID[6273561]
NPT963 Organism Hepatitis B virus Hepatitis B virus EC50 = 20.0 nM PMID[15658867]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 8000.0 nM PMID[15658867]
NPT419 Organism Oryctolagus cuniculus Oryctolagus cuniculus EC50 = 51000.0 nM PMID[15658867]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 9.4 ug.mL-1 PMID[15658861]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 0.6 ug.mL-1 PMID[15658861]
NPT610 Others Molecular identity unknown EC50 = 1500.0 nM PMID[15993062]
NPT610 Others Molecular identity unknown EC50 = 3100.0 nM PMID[15993062]
NPT610 Others Molecular identity unknown EC50 = 40000.0 nM PMID[15993062]
NPT610 Others Molecular identity unknown EC50 = 53000.0 nM PMID[15993062]
NPT32 Organism Mus musculus Mus musculus Activity = 10.0 n.a. PMID[15916444]
NPT32 Organism Mus musculus Mus musculus Activity = 7.0 n.a. PMID[15916444]
NPT32 Organism Mus musculus Mus musculus Activity = 13.0 n.a. PMID[15916444]
NPT32 Organism Mus musculus Mus musculus Activity = 6.0 n.a. PMID[15916444]
NPT32 Organism Mus musculus Mus musculus Activity = 17.2 n.a. PMID[15916444]
NPT32 Organism Mus musculus Mus musculus Activity = 1.0 n.a. PMID[15916444]
NPT32 Organism Mus musculus Mus musculus Activity = 0.0 n.a. PMID[15916444]
NPT32 Organism Mus musculus Mus musculus Activity = 14.2 n.a. PMID[15916444]
NPT32 Organism Mus musculus Mus musculus Activity = 3.0 n.a. PMID[15916444]
NPT32 Organism Mus musculus Mus musculus Activity = 11.0 n.a. PMID[15916444]
NPT32 Organism Mus musculus Mus musculus Activity = 2.0 n.a. PMID[15916444]
NPT32 Organism Mus musculus Mus musculus Activity = 15.0 n.a. PMID[15916444]
NPT164 Organism Human herpesvirus 4 Human herpesvirus 4 EC50 = 1100.0 nM PMID[15634003]
NPT27 Others Unspecified CC50 > 100000.0 nM PMID[15634003]
NPT610 Others Molecular identity unknown EC50 = 1600.0 nM PMID[15634003]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 1500.0 nM PMID[15634003]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 900.0 nM PMID[15634003]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 13500.0 nM PMID[15634003]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 EC50 = 6700.0 nM PMID[15634003]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 EC50 = 32300.0 nM PMID[15634003]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 320.0 nM PMID[15658858]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 36000.0 nM PMID[16392824]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 1400.0 nM PMID[16392824]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 1120.0 nM PMID[16392791]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 86600.0 nM PMID[16392791]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 EC50 = 1760.0 nM PMID[16392791]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 50000.0 nM PMID[16392791]
NPT3795 Organism Human immunodeficiency virus 2 Human immunodeficiency virus 2 EC50 > 50000.0 nM PMID[16392791]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 24000.0 nM PMID[16392824]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 MIC50 = 0.384 ug.mL-1 PMID[16420056]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 MIC50 = 0.384 ug.mL-1 PMID[16420056]
NPT334 Organism Vaccinia virus Vaccinia virus MIC50 > 400.0 ug.mL-1 PMID[16420056]
NPT195 Organism Vesicular stomatitis virus Vesicular stomatitis virus MIC50 > 400.0 ug.mL-1 PMID[16420056]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 MIC50 = 48.0 ug.mL-1 PMID[16420056]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 0.22 ug.mL-1 PMID[16480257]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 14.0 ug.mL-1 PMID[16480257]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 Inhibition = 96.0 % PMID[16321530]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 1090.0 nM PMID[16321530]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 3500.0 nM PMID[17004726]
NPT164 Organism Human herpesvirus 4 Human herpesvirus 4 EC50 = 330.0 nM PMID[17004726]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 30.0 nM PMID[17004726]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS EC50 = 480.0 nM PMID[17181162]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS EC50 = 12000.0 nM PMID[17181162]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 EC50 = 480.0 nM PMID[17181162]
NPT334 Organism Vaccinia virus Vaccinia virus EC50 = 300000.0 nM PMID[17181162]
NPT195 Organism Vesicular stomatitis virus Vesicular stomatitis virus EC50 > 500000.0 nM PMID[17181162]
NPT334 Organism Vaccinia virus Vaccinia virus MIC > 500000.0 nM PMID[17286431]
NPT195 Organism Vesicular stomatitis virus Vesicular stomatitis virus MIC > 500000.0 nM PMID[17286431]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS MIC = 480.0 nM PMID[17286431]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 MIC = 480.0 nM PMID[17286431]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 MIC = 60000.0 nM PMID[17286431]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS EC50 = 0.015 ug.mL-1 PMID[17298047]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS EC50 > 20.0 ug.mL-1 PMID[17298047]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 EC50 = 0.018 ug.mL-1 PMID[17298047]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 EC50 = 0.048 ug.mL-1 PMID[17298047]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 0.75 ug.mL-1 PMID[17298047]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 >= 25.1 ug.mL-1 PMID[17298047]
NPT27 Others Unspecified IC50 = 57730.0 nM PMID[17341060]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 1600.0 nM PMID[15615545]
NPT164 Organism Human herpesvirus 4 Human herpesvirus 4 EC50 = 1100.0 nM PMID[15615545]
NPT164 Organism Human herpesvirus 4 Human herpesvirus 4 EC50 = 5300.0 nM PMID[15615545]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 10000.0 nM PMID[15615545]
NPT27 Others Unspecified CC50 > 10000.0 nM PMID[15615545]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS MIC = 480.0 nM PMID[17092728]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 MIC = 800.0 nM PMID[17092728]
NPT334 Organism Vaccinia virus Vaccinia virus MIC = 300000.0 nM PMID[17092728]
NPT195 Organism Vesicular stomatitis virus Vesicular stomatitis virus MIC > 500000.0 nM PMID[17092728]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS MIC = 60000.0 nM PMID[17092728]
NPT6174 Organism Human herpesvirus 8 Human herpesvirus 8 IC50 > 100000.0 nM PMID[17402726]
NPT27 Others Unspecified IC50 > 100000.0 nM PMID[17402726]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS EC50 = 0.02 ug.mL-1 PMID[17518459]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 EC50 = 0.07 ug.mL-1 PMID[17518459]
NPT334 Organism Vaccinia virus Vaccinia virus EC50 > 400.0 ug.mL-1 PMID[17518459]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 40.0 ug.mL-1 PMID[17518459]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 7.0 ug.mL-1 PMID[17518459]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 IC50 = 390.0 nM PMID[17368024]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 1000.0 nM PMID[17539622]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 32000.0 nM PMID[17539622]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 1400.0 nM PMID[17622128]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 4000.0 nM PMID[17622128]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 36000.0 nM PMID[17622128]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 24000.0 nM PMID[17622128]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 1000.0 nM PMID[17672445]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 32000.0 nM PMID[17672445]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS MIC = 400.0 nM PMID[17672445]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 MIC = 400.0 nM PMID[17672445]
NPT334 Organism Vaccinia virus Vaccinia virus MIC > 250000.0 nM PMID[17672445]
NPT1750 Organism Human herpesvirus 5 Human herpesvirus 5 IC50 > 20000.0 nM PMID[17513108]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 IC50 = 2100.0 nM PMID[17513108]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 IC50 = 8100.0 nM PMID[17513108]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 EC50 = 0.02 ug.mL-1 PMID[17948980]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 EC50 = 0.05 ug.mL-1 PMID[17948980]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 0.23 ug.mL-1 PMID[17948980]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 10.2 ug.mL-1 PMID[17948980]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 2900.0 nM PMID[18052321]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 1000.0 nM PMID[18052321]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 74000.0 nM PMID[18052321]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 125000.0 nM PMID[18052321]
NPT2 Others Unspecified IC50 > 100000.0 nM PMID[18052321]
NPT1750 Organism Human herpesvirus 5 Human herpesvirus 5 IC50 > 20000.0 nM PMID[17434304]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 IC50 = 2100.0 nM PMID[17434304]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 IC50 = 8100.0 nM PMID[17434304]
NPT164 Organism Human herpesvirus 4 Human herpesvirus 4 IC50 = 6900.0 nM PMID[17434304]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 0.7 ug.mL-1 PMID[17869124]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 28.0 ug.mL-1 PMID[17869124]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 IC50 = 390.0 nM PMID[18086523]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 6000.0 nM PMID[17981031]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 > 444000.0 nM PMID[17325220]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 1300.0 nM PMID[17325220]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 EC50 = 3100.0 nM PMID[17325220]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 EC50 > 444000.0 nM PMID[17325220]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 8500.0 nM PMID[17325220]
NPT1762 Organism Macacine herpesvirus 1 Macacine herpesvirus 1 EC50 = 112000.0 nM PMID[17438061]
NPT1762 Organism Macacine herpesvirus 1 Macacine herpesvirus 1 EC50 = 118000.0 nM PMID[17438061]
NPT1762 Organism Macacine herpesvirus 1 Macacine herpesvirus 1 EC50 = 47500.0 nM PMID[17438061]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 1400.0 nM PMID[17438061]
NPT19368 SINGLE PROTEIN Thymidine kinase Human herpesvirus 2 IC50 = 200000.0 nM PMID[17438061]
NPT164 Organism Human herpesvirus 4 Human herpesvirus 4 EC50 = 1700.0 nM PMID[18082410]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 IC50 = 4.21 ug.mL-1 PMID[11678658]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 Activity = 6.0 ug ml-1 PMID[11678658]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 Ratio = 100000.0 n.a. PMID[11678658]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 IC50 = 2.0 ug.mL-1 PMID[11277765]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 0.8 ug.mL-1 PMID[12444692]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 EC50 = 2.4 ug.mL-1 PMID[12444692]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 IC50 = 10200.0 nM PMID[18363379]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 MIC = 0.384 ug.mL-1 PMID[17583388]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 MIC = 0.384 ug.mL-1 PMID[17583388]
NPT334 Organism Vaccinia virus Vaccinia virus MIC > 400.0 ug.mL-1 PMID[17583388]
NPT195 Organism Vesicular stomatitis virus Vesicular stomatitis virus MIC > 400.0 ug.mL-1 PMID[17583388]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 MIC = 48.0 ug.mL-1 PMID[17583388]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 0.17 ug.mL-1 PMID[17583388]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 16.0 ug.mL-1 PMID[17583388]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 EC50 = 2.3 ug.mL-1 PMID[8792629]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 EC50 = 1.5 ug.mL-1 PMID[9214738]
NPT2 Others Unspecified Ratio IC50/EC50 > 60.0 n.a. PMID[9214738]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 IC50 = 0.1 ug.mL-1 PMID[16378363]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 1100.0 nM PMID[15104498]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 EC50 = 1000.0 nM PMID[15104498]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 0.26 ug.mL-1 PMID[9599250]
NPT27 Others Unspecified IC50 > 67.0 ug.mL-1 PMID[9599250]
NPT2 Others Unspecified Ratio IC50/EC50 > 250.0 n.a. PMID[9599250]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 EC50 = 2.3 ug.mL-1 PMID[9599250]
NPT27 Others Unspecified IC50 > 10.0 ug.mL-1 PMID[9599250]
NPT2 Others Unspecified Ratio IC50/EC50 > 4.3 n.a. PMID[9599250]
NPT1750 Organism Human herpesvirus 5 Human herpesvirus 5 EC50 = 12.0 ug.mL-1 PMID[18707089]
NPT1750 Organism Human herpesvirus 5 Human herpesvirus 5 EC50 = 7.9 ug.mL-1 PMID[18707089]
NPT1750 Organism Human herpesvirus 5 Human herpesvirus 5 EC50 = 173.0 ug.mL-1 PMID[18707089]
NPT1750 Organism Human herpesvirus 5 Human herpesvirus 5 EC50 = 130.0 ug.mL-1 PMID[18707089]
NPT1750 Organism Human herpesvirus 5 Human herpesvirus 5 EC50 = 4.8 ug.mL-1 PMID[18707089]
NPT1750 Organism Human herpesvirus 5 Human herpesvirus 5 EC50 = 91.0 ug.mL-1 PMID[18707089]
NPT1750 Organism Human herpesvirus 5 Human herpesvirus 5 EC50 = 7.7 ug.mL-1 PMID[18707089]
NPT1750 Organism Human herpesvirus 5 Human herpesvirus 5 EC50 = 22.0 ug.mL-1 PMID[18707089]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 950.0 nM PMID[15497938]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 EC50 = 950.0 nM PMID[15497938]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 Activity = 6.0 ug ml-1 PMID[11858754]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 Activity = 3.25 n.a. PMID[8064297]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 Activity = 3.0 n.a. PMID[8064297]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 Activity = 2.0 n.a. PMID[8064297]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 0.24 ug.mL-1 PMID[18835175]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 13.0 ug.mL-1 PMID[18835175]
NPT164 Organism Human herpesvirus 4 Human herpesvirus 4 EC50 = 3300.0 nM PMID[19397271]
NPT27 Others Unspecified CC50 > 100000.0 nM PMID[19397271]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 IC50 = 0.5 ug.mL-1 PMID[17067157]
NPT3119 Organism Human coxsackievirus B3 Human coxsackievirus B3 IC50 = 25.0 ug.mL-1 PMID[16724853]
NPT742 Organism Influenza A virus Influenza A virus IC50 = 15.7 ug.mL-1 PMID[16724853]
NPT2 Others Unspecified Ratio CC50/IC50 > 2000.0 n.a. PMID[16724853]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 IC50 = 0.25 ug.mL-1 PMID[16724853]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 0.24 ug.mL-1 PMID[9584406]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 EC50 = 0.22 ug.mL-1 PMID[9584406]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 IC50 = 1.1 ug.mL-1 PMID[16441071]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 400.0 nM PMID[18614365]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 EC50 = 200.0 nM PMID[18614365]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 50000.0 nM PMID[18614365]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 2500.0 nM PMID[18614365]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 2900.0 nM PMID[18614365]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 61000.0 nM PMID[18614365]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 EC50 = 6000.0 nM PMID[18614365]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 EC50 > 100000.0 nM PMID[18614365]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 43000.0 nM PMID[18614365]
NPT164 Organism Human herpesvirus 4 Human herpesvirus 4 IC50 = 6900.0 nM PMID[18595689]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 IC50 = 8100.0 nM PMID[18595689]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 IC50 = 2100.0 nM PMID[18595689]
NPT1750 Organism Human herpesvirus 5 Human herpesvirus 5 IC50 > 20000.0 nM PMID[18595689]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 IC50 = 3040.0 nM PMID[19010684]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 IC50 = 31200.0 nM PMID[19010684]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 IC50 = 580.0 nM PMID[19010684]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 IC50 = 75070.0 nM PMID[19010684]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 IC50 = 320.0 nM PMID[19010684]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 IC50 = 9510.0 nM PMID[19010684]
NPT334 Organism Vaccinia virus Vaccinia virus IC50 = 384.0 nM PMID[19112024]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 0.18 ug.mL-1 PMID[19147352]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 EC50 = 0.36 ug.mL-1 PMID[19147352]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 1100.0 nM PMID[19226140]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 72000.0 nM PMID[19226140]
NPT1750 Organism Human herpesvirus 5 Human herpesvirus 5 EC50 = 7500.0 nM PMID[19226140]
NPT2262 Organism Human herpesvirus 5 strain AD169 Human herpesvirus 5 strain AD169 EC50 = 15000.0 nM PMID[19226140]
NPT2262 Organism Human herpesvirus 5 strain AD169 Human herpesvirus 5 strain AD169 EC50 = 4300.0 nM PMID[19226140]
NPT2262 Organism Human herpesvirus 5 strain AD169 Human herpesvirus 5 strain AD169 EC50 = 176000.0 nM PMID[19226140]
NPT2262 Organism Human herpesvirus 5 strain AD169 Human herpesvirus 5 strain AD169 EC50 = 7600.0 nM PMID[19226140]
NPT2262 Organism Human herpesvirus 5 strain AD169 Human herpesvirus 5 strain AD169 EC50 = 125000.0 nM PMID[19226140]
NPT2262 Organism Human herpesvirus 5 strain AD169 Human herpesvirus 5 strain AD169 EC50 = 1000.0 nM PMID[19226140]
NPT2262 Organism Human herpesvirus 5 strain AD169 Human herpesvirus 5 strain AD169 EC50 = 200000.0 nM PMID[19226140]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 Activity = 10.0 n.a. PMID[19217699]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 Activity = 6.0 ug ml-1 PMID[19217699]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 300.0 nM PMID[19410465]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 1300.0 nM PMID[19410465]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 EC50 = 1200.0 nM PMID[19410465]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 4400.0 nM PMID[19410465]
NPT19358 ORGANISM Equid herpesvirus 1 Equid herpesvirus 1 EC50 = 1.7 ug.mL-1 PMID[17846132]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 IC50 = 4300.0 nM PMID[19422205]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 IC50 = 6.86 ug.mL-1 PMID[19456117]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 250000.0 nM PMID[19645484]
NPT3795 Organism Human immunodeficiency virus 2 Human immunodeficiency virus 2 EC50 > 250000.0 nM PMID[19645484]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 50000.0 nM PMID[19645484]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 EC50 = 200.0 nM PMID[19645484]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 400.0 nM PMID[19645484]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 Activity = 12.0 % PMID[19285757]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 Activity = 28.0 % PMID[19285757]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 2000.0 nM PMID[19339082]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 1800.0 nM PMID[19339082]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 62200.0 nM PMID[19339082]
NPT2262 Organism Human herpesvirus 5 strain AD169 Human herpesvirus 5 strain AD169 EC50 = 178000.0 nM PMID[19339082]
NPT1750 Organism Human herpesvirus 5 Human herpesvirus 5 EC50 = 45000.0 nM PMID[19339082]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 MIC50 = 0.4 ug.mL-1 PMID[19324473]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 MIC50 = 0.4 ug.mL-1 PMID[19324473]
NPT334 Organism Vaccinia virus Vaccinia virus MIC50 > 250.0 ug.mL-1 PMID[19324473]
NPT195 Organism Vesicular stomatitis virus Vesicular stomatitis virus MIC50 > 250.0 ug.mL-1 PMID[19324473]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 MIC50 = 50.0 ug.mL-1 PMID[19324473]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 3000.0 nM PMID[19482481]
NPT27 Others Unspecified CC50 > 100000.0 nM PMID[19482481]
NPT3573 Organism Bovine viral diarrhea virus Bovine viral diarrhea virus 1 EC50 > 100000.0 nM PMID[19482481]
NPT4327 Organism Yellow fever virus Yellow fever virus EC50 > 100000.0 nM PMID[19482481]
NPT3878 Organism Mammalian orthoreovirus 1 Mammalian orthoreovirus 1 EC50 > 100000.0 nM PMID[19482481]
NPT6258 Organism Human coxsackievirus B2 Human coxsackievirus B2 EC50 > 100000.0 nM PMID[19482481]
NPT70 Organism Respiratory syncytial virus Respiratory syncytial virus EC50 > 100000.0 nM PMID[19482481]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. EC50 > 100000.0 nM PMID[19482481]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. IC50 = 390.0 nM PMID[19700316]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 840.0 nM PMID[20064723]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 26700.0 nM PMID[20064723]
NPT1750 Organism Human herpesvirus 5 Human herpesvirus 5 IC50 = 20000.0 nM PMID[20167488]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 IC50 = 8100.0 nM PMID[20167488]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 IC50 = 13000.0 nM PMID[20038128]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 Ratio = 1000.0 n.a. PMID[19892441]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 Activity = 6.0 ug ml-1 PMID[19892441]
NPT1106 Organism Human poliovirus 1 Human poliovirus 1 EC50 > 100000.0 nM PMID[20359898]
NPT6258 Organism Human coxsackievirus B2 Human coxsackievirus B2 EC50 > 100000.0 nM PMID[20359898]
NPT4327 Organism Yellow fever virus Yellow fever virus EC50 > 100000.0 nM PMID[20359898]
NPT3573 Organism Bovine viral diarrhea virus Bovine viral diarrhea virus 1 EC50 > 100000.0 nM PMID[20359898]
NPT27 Others Unspecified CC50 > 100000.0 nM PMID[20359898]
NPT334 Organism Vaccinia virus Vaccinia virus EC50 > 100000.0 nM PMID[20359898]
NPT70 Organism Respiratory syncytial virus Respiratory syncytial virus EC50 > 100000.0 nM PMID[20359898]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 3000.0 nM PMID[20359898]
NPT605 Organism Homo sapiens Homo sapiens Activity = 0.23 % PMID[20022146]
NPT2 Others Unspecified IC50 > 20000.0 nM PMID[20403696]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 IC50 = 2100.0 nM PMID[20403696]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 IC50 = 8100.0 nM PMID[20403696]
NPT1762 Organism Macacine herpesvirus 1 Macacine herpesvirus 1 Activity = 33.0 % PMID[19858259]
NPT1762 Organism Macacine herpesvirus 1 Macacine herpesvirus 1 EC50 = 19300.0 nM PMID[19858259]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 19300.0 nM PMID[19858259]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 EC50 = 19300.0 nM PMID[19858259]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 IC50 = 4300.0 nM PMID[20092288]
NPT605 Organism Homo sapiens Homo sapiens Ratio = 0.19 n.a. PMID[20038622]
NPT605 Organism Homo sapiens Homo sapiens Ratio = 0.2 n.a. PMID[20038622]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS EC50 = 160.0 nM PMID[20809641]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS EC50 = 125000.0 nM PMID[20809641]
NPT5012 Organism Human herpesvirus 2 strain G Human herpesvirus 2 strain G EC50 = 300.0 nM PMID[20809641]
NPT1750 Organism Human herpesvirus 5 Human herpesvirus 5 EC50 = 3690.0 nM PMID[20809641]
NPT1750 Organism Human herpesvirus 5 Human herpesvirus 5 EC50 = 60400.0 nM PMID[20809641]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 3300.0 nM PMID[21128666]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 62000.0 nM PMID[21128666]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 EC50 = 3000.0 nM PMID[19770274]
NPT2 Others Unspecified Ratio CC50/EC50 > 150.0 n.a. PMID[19770274]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 80.0 nM PMID[19770274]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 12000.0 nM PMID[19770274]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 600.0 nM PMID[19770274]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 11.0 nM PMID[19770274]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 4400.0 nM PMID[19770274]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 EC50 = 4700.0 nM PMID[19770274]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 EC50 = 9600.0 nM PMID[19770274]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 EC50 = 4900.0 nM PMID[19770274]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 EC50 = 6600.0 nM PMID[19770274]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 EC50 > 440000.0 nM PMID[19770274]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 Ratio EC50 > 100.0 n.a. PMID[19770274]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 EC50 > 100000.0 nM PMID[19770274]
NPT5012 Organism Human herpesvirus 2 strain G Human herpesvirus 2 strain G EC50 = 200.0 nM PMID[21232828]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS EC50 = 400.0 nM PMID[21232828]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. EC50 = 1000.0 nM PMID[21232828]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS EC50 = 10000.0 nM PMID[21232828]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 16500.0 nM PMID[21232828]
NPT334 Organism Vaccinia virus Vaccinia virus EC50 > 250000.0 nM PMID[21232828]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 > 50000.0 nM PMID[20733037]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 11000.0 nM PMID[20733037]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 35000.0 nM PMID[20733037]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 16000.0 nM PMID[20733037]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 26000.0 nM PMID[20733037]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 31000.0 nM PMID[20733037]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 10000.0 nM PMID[20733037]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 22000.0 nM PMID[20733037]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 EC50 = 43000.0 nM PMID[20733037]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 EC50 = 33000.0 nM PMID[20733037]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 EC50 = 24000.0 nM PMID[20733037]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 EC50 = 11000.0 nM PMID[20733037]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 EC50 > 50000.0 nM PMID[20733037]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 EC50 = 18000.0 nM PMID[20733037]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 EC50 = 42000.0 nM PMID[20733037]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. IC50 = 5800.0 nM PMID[21256035]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 IC50 = 58700.0 nM PMID[21256035]
NPT27 Others Unspecified CC50 > 1778000.0 nM PMID[21256035]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 Inhibition = 95.0 % PMID[21376603]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 IC50 = 990.0 nM PMID[21376603]
NPT2 Others Unspecified Ratio CC50/IC50 = 869.0 n.a. PMID[21376603]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 1160.0 nM PMID[21334891]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 EC50 = 1720.0 nM PMID[21334891]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 IC50 = 300.0 nM PMID[21356589]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 IC50 = 1270.0 nM PMID[21356589]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 1100.0 nM PMID[21376429]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 IC50 = 17000.0 nM PMID[21473608]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 3640.0 nM PMID[21745746]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. EC50 = 1560.0 nM PMID[21745746]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 71600.0 nM PMID[21745746]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 76900.0 nM PMID[21745746]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS EC50 = 300.0 nM PMID[21745746]
NPT5012 Organism Human herpesvirus 2 strain G Human herpesvirus 2 strain G EC50 = 230.0 nM PMID[21745746]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS EC50 = 7300.0 nM PMID[21745746]
NPT334 Organism Vaccinia virus Vaccinia virus EC50 > 250000.0 nM PMID[21745746]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 111000.0 nM PMID[21696963]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 43000.0 nM PMID[21696963]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. EC50 = 1400.0 nM PMID[21696963]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 4900.0 nM PMID[21696963]
NPT27 Others Unspecified CC50 > 100000.0 nM PMID[21696963]
NPT334 Organism Vaccinia virus Vaccinia virus EC50 > 250000.0 nM PMID[21696963]
NPT5012 Organism Human herpesvirus 2 strain G Human herpesvirus 2 strain G EC50 = 400.0 nM PMID[21696963]
NPT343 Organism Felid herpesvirus 1 Felid herpesvirus 1 EC50 = 1000.0 nM PMID[21696963]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS EC50 = 50000.0 nM PMID[21696963]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS EC50 = 400.0 nM PMID[21696963]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS EC50 = 270.0 nM PMID[21565516]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS EC50 = 27100.0 nM PMID[21565516]
NPT5012 Organism Human herpesvirus 2 strain G Human herpesvirus 2 strain G EC50 = 230.0 nM PMID[21565516]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. EC50 = 3000.0 nM PMID[21565516]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 69300.0 nM PMID[21565516]
NPT334 Organism Vaccinia virus Vaccinia virus EC50 > 250000.0 nM PMID[21565516]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS IC50 = 600.0 nM PMID[21812420]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS EC50 = 3000.0 nM PMID[22047799]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 Inhibition = 66.3 % PMID[22148431]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 Inhibition = 60.6 % PMID[22148431]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 26600.0 nM PMID[22459876]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. EC50 = 490.0 nM PMID[22459876]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS EC50 > 250000.0 nM PMID[22459876]
NPT195 Organism Vesicular stomatitis virus Vesicular stomatitis virus EC50 > 250000.0 nM PMID[22459876]
NPT334 Organism Vaccinia virus Vaccinia virus EC50 > 250000.0 nM PMID[22459876]
NPT5012 Organism Human herpesvirus 2 strain G Human herpesvirus 2 strain G EC50 = 400.0 nM PMID[22459876]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS EC50 = 200.0 nM PMID[22459876]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 2180.0 nM PMID[22578783]
NPT24742 ORGANISM Human herpesvirus 3 strain Oka vaccine Human herpesvirus 3 strain Oka vaccine EC50 = 2500.0 nM PMID[22578783]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 92000.0 nM PMID[22578783]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS EC50 = 3000.0 nM PMID[22513121]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 IC50 = 2900.0 nM PMID[22607883]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 IC50 = 2800.0 nM PMID[22607883]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 IC50 = 1900.0 nM PMID[22607883]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 2840.0 nM PMID[22858222]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. EC50 = 1640.0 nM PMID[22858222]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 54000.0 nM PMID[22858222]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 37000.0 nM PMID[22858222]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 530.0 nM PMID[22858222]
NPT5012 Organism Human herpesvirus 2 strain G Human herpesvirus 2 strain G EC50 = 380.0 nM PMID[22858222]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 >= 212000.0 nM PMID[22858222]
NPT334 Organism Vaccinia virus Vaccinia virus EC50 > 1000000.0 nM PMID[22858222]
NPT669 Individual Protein Solute carrier family 22 member 8 Homo sapiens Activity = 64.3 % PMID[11861798]
NPT665 Individual Protein Solute carrier family 22 member 6 Homo sapiens Activity = 67.0 % PMID[11861798]
NPT667 Individual Protein Solute carrier family 22 member 8 Rattus norvegicus Activity = 7.66 % PMID[12358729]
NPT2 Others Unspecified Ratio CC50/EC50 = 61.9 n.a. PMID[22921079]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 1.6 ug.mL-1 PMID[22921079]
NPT5012 Organism Human herpesvirus 2 strain G Human herpesvirus 2 strain G EC50 = 1.8 ug.mL-1 PMID[22921079]
NPT2 Others Unspecified Ratio CC50/EC50 = 81.3 n.a. PMID[22921079]
NPT2 Others Unspecified Ratio CC50/EC50 = 72.2 n.a. PMID[22921079]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 Inhibition = 94.0 % PMID[22921079]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 2.1 ug.mL-1 PMID[22921079]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 1700.0 nM PMID[22954898]
NPT27 Others Unspecified Ratio CC50/EC50 > 1176.0 n.a. PMID[22954898]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 530000.0 nM PMID[22954898]
NPT27 Others Unspecified Ratio CC50/EC50 > 3.8 n.a. PMID[22954898]
NPT334 Organism Vaccinia virus Vaccinia virus EC50 > 250000.0 nM PMID[23047229]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS EC50 = 400.0 nM PMID[23047229]
NPT5012 Organism Human herpesvirus 2 strain G Human herpesvirus 2 strain G EC50 = 400.0 nM PMID[23047229]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS EC50 = 250000.0 nM PMID[23047229]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. EC50 = 2700.0 nM PMID[23047229]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 15000.0 nM PMID[23047229]
NPT3574 Organism Herpes simplex virus (type 1 / strain F) Herpes simplex virus (type 1 / strain F) EC50 = 500.0 nM PMID[22944333]
NPT2 Others Unspecified Ratio CC50/EC50 > 106.95 n.a. PMID[22704890]
NPT2 Others Unspecified Ratio CC50/EC50 > 166.67 n.a. PMID[22704890]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. EC50 = 1870.0 nM PMID[22704890]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 1200.0 nM PMID[22704890]
NPT72 Individual Protein Solute carrier organic anion transporter family member 1B3 Homo sapiens Inhibition = -2.0 % PMID[22541068]
NPT73 Individual Protein Solute carrier organic anion transporter family member 1B1 Homo sapiens Inhibition = 2.3 % PMID[22541068]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS EC50 = 44000.0 nM PMID[23099097]
NPT195 Organism Vesicular stomatitis virus Vesicular stomatitis virus EC50 > 250000.0 nM PMID[23099097]
NPT334 Organism Vaccinia virus Vaccinia virus EC50 >= 250000.0 nM PMID[23099097]
NPT5012 Organism Human herpesvirus 2 strain G Human herpesvirus 2 strain G EC50 = 140.0 nM PMID[23099097]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS EC50 = 140.0 nM PMID[23099097]
NPT3574 Organism Herpes simplex virus (type 1 / strain F) Herpes simplex virus (type 1 / strain F) IC50 = 0.2 ug.mL-1 PMID[23194476]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 22000.0 nM PMID[23141915]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 760.0 nM PMID[23141915]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 Activity = 100.0 % DOI[10.1007/s00044-011-9960-2]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 1.5 ug.mL-1 DOI[10.1007/s00044-011-9574-8]
NPT2 Others Unspecified Ratio CC50/EC50 = 850.0 n.a. DOI[10.1007/s00044-011-9574-8]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 Activity < 0.012 ug ml-1 DOI[10.1007/s00044-010-9338-x]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 Activity = 1.6 ug ml-1 DOI[10.1007/s00044-010-9338-x]
NPT2 Others Unspecified Ratio CC50/EC50 = 880.0 n.a. DOI[10.1007/s00044-007-9035-6]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 Inhibition = 96.0 % DOI[10.1007/s00044-007-9035-6]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 1090.0 nM DOI[10.1007/s00044-007-9035-6]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 3000.0 nM DOI[10.1007/s00044-010-9513-0]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 23.0 ug.mL-1 DOI[10.1007/s00044-011-9776-0]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 0.44 ug.mL-1 DOI[10.1007/s00044-011-9776-0]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS MIC = 300.0 ug.mL-1 DOI[10.1007/s00044-012-0127-6]
NPT195 Organism Vesicular stomatitis virus Vesicular stomatitis virus MIC > 500.0 ug.mL-1 DOI[10.1007/s00044-012-0127-6]
NPT334 Organism Vaccinia virus Vaccinia virus MIC > 500.0 ug.mL-1 DOI[10.1007/s00044-012-0127-6]
NPT5012 Organism Human herpesvirus 2 strain G Human herpesvirus 2 strain G MIC = 20.0 ug.mL-1 DOI[10.1007/s00044-012-0127-6]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS MIC = 2.4 ug.mL-1 DOI[10.1007/s00044-012-0127-6]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS EC50 > 250000.0 nM PMID[32214762]
NPT195 Organism Vesicular stomatitis virus Vesicular stomatitis virus EC50 > 250000.0 nM PMID[32214762]
NPT334 Organism Vaccinia virus Vaccinia virus EC50 > 250000.0 nM PMID[32214762]
NPT5012 Organism Human herpesvirus 2 strain G Human herpesvirus 2 strain G EC50 = 700.0 nM PMID[32214762]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS EC50 = 1000.0 nM PMID[32214762]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 3000.0 nM DOI[10.1007/s00044-012-0342-1]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 IC50 = 13000.0 nM PMID[23219702]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 EC50 = 58600.0 nM PMID[23419738]
NPT3574 Organism Herpes simplex virus (type 1 / strain F) Herpes simplex virus (type 1 / strain F) EC50 = 1700.0 nM PMID[23419738]
NPT963 Organism Hepatitis B virus Hepatitis B virus IC50 > 1000000.0 nM PMID[23369536]
NPT27 Others Unspecified CC50 = 630000.0 nM PMID[23369536]
NPT32 Organism Mus musculus Mus musculus Activity = 31.2 % PMID[23369536]
NPT32 Organism Mus musculus Mus musculus Activity = 18.7 % PMID[23369536]
NPT32 Organism Mus musculus Mus musculus Activity = 15.1 % PMID[23369536]
NPT32 Organism Mus musculus Mus musculus Activity = 1.2 % PMID[23369536]
NPT334 Organism Vaccinia virus Vaccinia virus EC50 > 250000.0 nM PMID[23603046]
NPT5012 Organism Human herpesvirus 2 strain G Human herpesvirus 2 strain G EC50 = 80.0 nM PMID[23603046]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS EC50 = 29000.0 nM PMID[23603046]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS EC50 = 80.0 nM PMID[23603046]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS EC50 = 112000.0 nM PMID[23811093]
NPT195 Organism Vesicular stomatitis virus Vesicular stomatitis virus EC50 > 250000.0 nM PMID[23811093]
NPT334 Organism Vaccinia virus Vaccinia virus EC50 > 250000.0 nM PMID[23811093]
NPT5012 Organism Human herpesvirus 2 strain G Human herpesvirus 2 strain G EC50 = 200.0 nM PMID[23811093]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS EC50 = 400.0 nM PMID[23811093]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 143600.0 nM PMID[23811093]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. EC50 = 26.0 nM PMID[23811093]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS EC50 = 112000.0 nM PMID[23911856]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 26000.0 nM PMID[23911856]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. EC50 = 2100.0 nM PMID[23911856]
NPT5012 Organism Human herpesvirus 2 strain G Human herpesvirus 2 strain G EC50 = 200.0 nM PMID[23911856]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS EC50 = 200.0 nM PMID[23911856]
NPT195 Organism Vesicular stomatitis virus Vesicular stomatitis virus EC50 > 250000.0 nM PMID[23911856]
NPT334 Organism Vaccinia virus Vaccinia virus EC50 > 250000.0 nM PMID[23911856]
NPT72 Individual Protein Solute carrier organic anion transporter family member 1B3 Homo sapiens Inhibition = 105.48 % PMID[23571415]
NPT73 Individual Protein Solute carrier organic anion transporter family member 1B1 Homo sapiens Inhibition = 103.39 % PMID[23571415]
NPT343 Organism Felid herpesvirus 1 Felid herpesvirus 1 EC50 > 100000.0 nM PMID[24177359]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS EC50 = 23000.0 nM PMID[24177359]
NPT5012 Organism Human herpesvirus 2 strain G Human herpesvirus 2 strain G EC50 = 200.0 nM PMID[24177359]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS EC50 = 230.0 nM PMID[24177359]
NPT24 Organism Human immunodeficiency virus 1 Human immunodeficiency virus 1 EC50 > 250000.0 nM PMID[24177359]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS EC50 = 18000.0 nM PMID[24185376]
NPT5012 Organism Human herpesvirus 2 strain G Human herpesvirus 2 strain G EC50 = 500.0 nM PMID[24185376]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS EC50 = 320.0 nM PMID[24185376]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. Ratio CC50/EC50 > 10.4 n.a. PMID[24486419]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. Ratio CC50/EC50 = 30.3 n.a. PMID[24486419]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 EC50 = 9600.0 nM PMID[24486419]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 3300.0 nM PMID[24486419]
NPT24742 ORGANISM Human herpesvirus 3 strain Oka vaccine Human herpesvirus 3 strain Oka vaccine EC50 = 2600.0 nM PMID[24690527]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 140000.0 nM PMID[24690527]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS EC50 = 200.0 nM PMID[24690527]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 50000.0 nM PMID[24690527]
NPT5012 Organism Human herpesvirus 2 strain G Human herpesvirus 2 strain G EC50 = 100.0 nM PMID[24690527]
NPT195 Organism Vesicular stomatitis virus Vesicular stomatitis virus ED50 = 1411.0 umol/L PMID[25515560]
NPT27 Others Unspecified CC50 > 100000.0 nM PMID[25014745]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS EC50 = 3000.0 nM PMID[25014745]
NPT27 Others Unspecified CC50 > 100000.0 nM PMID[25082514]
NPT3573 Organism Bovine viral diarrhea virus Bovine viral diarrhea virus 1 EC50 > 100000.0 nM PMID[25082514]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. CC50 > 100000.0 nM PMID[25082514]
NPT4327 Organism Yellow fever virus Yellow fever virus EC50 > 100000.0 nM PMID[25082514]
NPT337 Organism Reovirus sp. Reovirus sp. EC50 > 100000.0 nM PMID[25082514]
NPT1539 Organism Human coxsackievirus B5 Human coxsackievirus B5 EC50 > 100000.0 nM PMID[25082514]
NPT4691 Organism Human poliovirus 1 strain Sabin Human poliovirus 1 strain Sabin EC50 > 100000.0 nM PMID[25082514]
NPT70 Organism Respiratory syncytial virus Respiratory syncytial virus EC50 > 100000.0 nM PMID[25082514]
NPT195 Organism Vesicular stomatitis virus Vesicular stomatitis virus EC50 > 100000.0 nM PMID[25082514]
NPT334 Organism Vaccinia virus Vaccinia virus EC50 > 100000.0 nM PMID[25082514]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 1200.0 nM PMID[25082514]
NPT27 Others Unspecified CC50 > 100000.0 nM PMID[25913116]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 2800.0 nM PMID[25913116]
NPT712 Individual Protein Bile salt export pump Rattus norvegicus IC50 > 1000000.0 nM PMID[21965623]
NPT713 Individual Protein Bile salt export pump Homo sapiens IC50 > 1000000.0 nM PMID[21965623]
NPT665 Individual Protein Solute carrier family 22 member 6 Homo sapiens FC = 1.7 n.a. PMID[22190696]
NPT669 Individual Protein Solute carrier family 22 member 8 Homo sapiens FC = 1.7 n.a. PMID[22190696]
NPT665 Individual Protein Solute carrier family 22 member 6 Homo sapiens Ratio = 0.5 uL/min PMID[22190696]
NPT669 Individual Protein Solute carrier family 22 member 8 Homo sapiens Ratio = 1.0 uL/min PMID[22190696]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS EC50 = 2000.0 nM PMID[26001344]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS EC50 = 200.0 nM PMID[26001344]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 33000.0 nM PMID[26001344]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 1500.0 nM PMID[26001344]
NPT334 Organism Vaccinia virus Vaccinia virus EC50 > 250000.0 nM PMID[26001344]
NPT5012 Organism Human herpesvirus 2 strain G Human herpesvirus 2 strain G EC50 = 80.0 nM PMID[26001344]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. EC50 > 1000000.0 nM PMID[26048809]
NPT27 Others Unspecified CC50 > 100000.0 nM PMID[26048809]
NPT27 Others Unspecified CC50 > 1000000.0 nM PMID[26048809]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. EC50 > 100000.0 nM PMID[26048809]
NPT27 Others Unspecified CC50 = 13000.0 nM PMID[26119992]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS EC50 = 3000.0 nM PMID[26119992]
NPT24742 ORGANISM Human herpesvirus 3 strain Oka vaccine Human herpesvirus 3 strain Oka vaccine EC50 = 1820.0 nM PMID[26443550]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 54500.0 nM PMID[26443550]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 6400.0 nM PMID[26460883]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 EC50 = 1020.0 nM PMID[26460883]
NPT3574 Organism Herpes simplex virus (type 1 / strain F) Herpes simplex virus (type 1 / strain F) EC50 = 660.0 nM PMID[26460883]
NPT1750 Organism Human herpesvirus 5 Human herpesvirus 5 EC50 = 18900.0 nM PMID[26460883]
NPT27 Others Unspecified CC50 > 100000.0 nM PMID[26460883]
NPT1539 Organism Human coxsackievirus B5 Human coxsackievirus B5 EC50 > 100000.0 nM PMID[26479028]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS EC50 = 3000.0 nM PMID[26479028]
NPT27 Others Unspecified CC50 > 100000.0 nM PMID[26443549]
NPT3573 Organism Bovine viral diarrhea virus Bovine viral diarrhea virus 1 EC50 > 100000.0 nM PMID[26443549]
NPT4327 Organism Yellow fever virus Yellow fever virus EC50 > 100000.0 nM PMID[26443549]
NPT1539 Organism Human coxsackievirus B5 Human coxsackievirus B5 EC50 > 100000.0 nM PMID[26443549]
NPT6367 Organism Human respiratory syncytial virus Human respiratory syncytial virus EC50 > 100000.0 nM PMID[26443549]
NPT4691 Organism Human poliovirus 1 strain Sabin Human poliovirus 1 strain Sabin EC50 > 100000.0 nM PMID[26443549]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 1200.0 nM PMID[26443549]
NPT195 Organism Vesicular stomatitis virus Vesicular stomatitis virus EC50 > 100000.0 nM PMID[26443549]
NPT334 Organism Vaccinia virus Vaccinia virus EC50 > 100000.0 nM PMID[26443549]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 2200.0 nM PMID[26638041]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 EC50 = 270.0 nM PMID[26638041]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 FC = 1000.0 n.a. PMID[26638041]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 FC = 10000.0 n.a. PMID[26638041]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS FC = 4.3 n.a. PMID[26819664]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS Activity = 33.3 PFU/ml PMID[26819664]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS FC = 8.5 n.a. PMID[26819664]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS FC = 2300.0 n.a. PMID[26819664]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS EC50 = 70.0 nM PMID[26819664]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 FC = 1.8 n.a. PMID[26819664]
NPT27 Others Unspecified CC50 > 100000.0 nM PMID[27161176]
NPT334 Organism Vaccinia virus Vaccinia virus EC50 = 1500.0 nM PMID[27161176]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 27000.0 nM PMID[27128178]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. EC50 = 1900.0 nM PMID[27639368]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. EC50 = 26000.0 nM PMID[27639368]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. CC50 = 191000.0 nM PMID[27639368]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. EC50 = 80.0 nM PMID[27639368]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. EC50 = 112000.0 nM PMID[27639368]
NPT20529 NON-MOLECULAR NON-PROTEIN TARGET n.a. EC50 = 200.0 nM PMID[27639368]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS EC50 = 250000.0 nM PMID[27750154]
NPT5012 Organism Human herpesvirus 2 strain G Human herpesvirus 2 strain G EC50 = 400.0 nM PMID[27750154]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS EC50 = 200.0 nM PMID[27750154]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 50300.0 nM PMID[27750154]
NPT24742 ORGANISM Human herpesvirus 3 strain Oka vaccine Human herpesvirus 3 strain Oka vaccine EC50 = 800.0 nM PMID[27750154]
NPT3574 Organism Herpes simplex virus (type 1 / strain F) Herpes simplex virus (type 1 / strain F) IC50 = 410.0 nM PMID[27792321]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS EC50 = 200.0 nM PMID[26114811]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 EC50 = 100.0 nM PMID[26114811]
NPT334 Organism Vaccinia virus Vaccinia virus EC50 > 250000.0 nM PMID[26114811]
NPT195 Organism Vesicular stomatitis virus Vesicular stomatitis virus EC50 > 250000.0 nM PMID[26114811]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS EC50 = 10000.0 nM PMID[26114811]
NPT2262 Organism Human herpesvirus 5 strain AD169 Human herpesvirus 5 strain AD169 EC50 = 1240.0 nM PMID[26114811]
NPT1750 Organism Human herpesvirus 5 Human herpesvirus 5 EC50 = 510.0 nM PMID[26114811]
NPT24742 ORGANISM Human herpesvirus 3 strain Oka vaccine Human herpesvirus 3 strain Oka vaccine EC50 = 1690.0 nM PMID[26114811]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 49300.0 nM PMID[26114811]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 3000.0 nM PMID[28129981]
NPT713 Individual Protein Bile salt export pump Homo sapiens IC50 > 135000.0 nM PMID[20829430]
NPT713 Individual Protein Bile salt export pump Homo sapiens IC50 > 1000000.0 nM PMID[22961681]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 IC50 = 1730.0 nM PMID[28408228]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 IC50 > 444000.0 nM PMID[28408228]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 IC50 = 27800.0 nM PMID[28408228]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 IC50 = 3500.0 nM PMID[28408228]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 IC50 = 17300.0 nM PMID[28408228]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 IC95 = 6900.0 nM PMID[28408228]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 IC95 > 444000.0 nM PMID[28408228]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 IC95 = 111000.0 nM PMID[28408228]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 IC95 = 13900.0 nM PMID[28408228]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 IC95 = 138800.0 nM PMID[28408228]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS EC50 = 400.0 nM PMID[28829913]
NPT5012 Organism Human herpesvirus 2 strain G Human herpesvirus 2 strain G EC50 = 400.0 nM PMID[28829913]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS EC50 = 60000.0 nM PMID[28829913]
NPT24742 ORGANISM Human herpesvirus 3 strain Oka vaccine Human herpesvirus 3 strain Oka vaccine EC50 = 1880.0 nM PMID[28829913]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 73000.0 nM PMID[28829913]
NPT713 Individual Protein Bile salt export pump Homo sapiens IC50 > 133000.0 nM PMID[23956101]
NPT24742 ORGANISM Human herpesvirus 3 strain Oka vaccine Human herpesvirus 3 strain Oka vaccine EC50 = 3020.0 nM PMID[28682067]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 20700.0 nM PMID[28682067]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS EC50 = 400.0 nM PMID[28757102]
NPT5012 Organism Human herpesvirus 2 strain G Human herpesvirus 2 strain G EC50 = 180.0 nM PMID[28757102]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS EC50 = 54000.0 nM PMID[28757102]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 1500.0 nM PMID[28757102]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 38900.0 nM PMID[28757102]
NPT334 Organism Vaccinia virus Vaccinia virus EC50 > 250000.0 nM PMID[28757102]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 Activity = 89.6 % PMID[28943043]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 Activity = 7.92 % PMID[28943043]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 Activity = 1.36 % PMID[28943043]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 Activity = 1.13 % PMID[28943043]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 Activity = 92.6 % PMID[28943043]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 Activity = 6.22 % PMID[28943043]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 Activity = 0.44 % PMID[28943043]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 Activity = 0.76 % PMID[28943043]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS EC50 = 800.0 nM PMID[29880251]
NPT5012 Organism Human herpesvirus 2 strain G Human herpesvirus 2 strain G EC50 = 400.0 nM PMID[29880251]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS EC50 = 126000.0 nM PMID[29880251]
NPT334 Organism Vaccinia virus Vaccinia virus EC50 > 250000.0 nM PMID[29880251]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 3550.0 nM PMID[29880251]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 14870.0 nM PMID[29880251]
NPT21954 CELL-LINE Vero 76 Chlorocebus sabaeus CC50 > 100000.0 nM PMID[29028528]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS EC50 = 1800.0 nM PMID[29028528]
NPT3574 Organism Herpes simplex virus (type 1 / strain F) Herpes simplex virus (type 1 / strain F) IC50 = 150.0 nM PMID[29099182]
NPT2 Others Unspecified Ratio CC50/IC50 > 1333.0 n.a. PMID[29099182]
NPT24742 ORGANISM Human herpesvirus 3 strain Oka vaccine Human herpesvirus 3 strain Oka vaccine EC50 = 2350.0 nM PMID[29945100]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 133300.0 nM PMID[29945100]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 IC50 = 0.00311 nM PMID[28771358]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 IC50 = 0.00475 nM PMID[28771358]
NPT24742 ORGANISM Human herpesvirus 3 strain Oka vaccine Human herpesvirus 3 strain Oka vaccine EC50 = 2930.0 nM PMID[29407990]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 54400.0 nM PMID[29407990]
NPT2 Others Unspecified Ratio CC50/EC50 > 150.0 n.a. PMID[29407990]
NPT2 Others Unspecified Ratio CC50/EC50 > 8.0 n.a. PMID[29407990]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS EC50 = 1200.0 nM PMID[29407990]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS EC50 = 94000.0 nM PMID[29407990]
NPT5012 Organism Human herpesvirus 2 strain G Human herpesvirus 2 strain G EC50 = 700.0 nM PMID[29407990]
NPT334 Organism Vaccinia virus Vaccinia virus EC50 > 250000.0 nM PMID[29407990]
NPT3574 Organism Herpes simplex virus (type 1 / strain F) Herpes simplex virus (type 1 / strain F) IC50 = 410.0 nM PMID[30106288]
NPT3574 Organism Herpes simplex virus (type 1 / strain F) Herpes simplex virus (type 1 / strain F) Activity = 0.1 % PMID[29602675]
NPT24742 ORGANISM Human herpesvirus 3 strain Oka vaccine Human herpesvirus 3 strain Oka vaccine EC50 = 3370.0 nM PMID[29550734]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 14120.0 nM PMID[29550734]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS EC50 = 300.0 nM PMID[29550734]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS EC50 > 88000.0 nM PMID[29550734]
NPT5012 Organism Human herpesvirus 2 strain G Human herpesvirus 2 strain G EC50 = 290.0 nM PMID[29550734]
NPT24742 ORGANISM Human herpesvirus 3 strain Oka vaccine Human herpesvirus 3 strain Oka vaccine EC50 = 5310.0 nM PMID[29268134]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 53510.0 nM PMID[29268134]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS EC50 = 380.0 nM PMID[29268134]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS EC50 = 88810.0 nM PMID[29268134]
NPT5012 Organism Human herpesvirus 2 strain G Human herpesvirus 2 strain G EC50 = 290.0 nM PMID[29268134]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS EC50 = 470.0 nM PMID[29670705]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS EC50 > 88800.0 nM PMID[29670705]
NPT5012 Organism Human herpesvirus 2 strain G Human herpesvirus 2 strain G EC50 = 340.0 nM PMID[29670705]
NPT24742 ORGANISM Human herpesvirus 3 strain Oka vaccine Human herpesvirus 3 strain Oka vaccine EC50 = 2840.0 nM PMID[29670705]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 54800.0 nM PMID[29670705]
NPT3574 Organism Herpes simplex virus (type 1 / strain F) Herpes simplex virus (type 1 / strain F) IC50 = 1290.0 nM PMID[30194008]
NPT2 Others Unspecified Ratio CC50/IC50 > 1500.0 n.a. PMID[30194008]
NPT3574 Organism Herpes simplex virus (type 1 / strain F) Herpes simplex virus (type 1 / strain F) EC50 = 600.0 nM PMID[30286952]
NPT5012 Organism Human herpesvirus 2 strain G Human herpesvirus 2 strain G EC50 = 600.0 nM PMID[30286952]
NPT3574 Organism Herpes simplex virus (type 1 / strain F) Herpes simplex virus (type 1 / strain F) EC50 = 2000.0 nM PMID[30286952]
NPT334 Organism Vaccinia virus Vaccinia virus EC50 > 250000.0 nM PMID[30286952]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 36740.0 nM PMID[30098481]
NPT24742 ORGANISM Human herpesvirus 3 strain Oka vaccine Human herpesvirus 3 strain Oka vaccine EC50 = 1260.0 nM PMID[30098481]
NPT2 Others Unspecified CC50 > 440000.0 nM PMID[30098481]
NPT334 Organism Vaccinia virus Vaccinia virus EC50 > 250000.0 nM PMID[30098481]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS EC50 = 10000.0 nM PMID[30098481]
NPT5012 Organism Human herpesvirus 2 strain G Human herpesvirus 2 strain G EC50 = 200.0 nM PMID[30098481]
NPT1766 Organism Human herpesvirus 1 strain KOS Human herpesvirus 1 strain KOS EC50 = 200.0 nM PMID[30098481]
NPT20555 ORGANISM SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2 Inhibition = 8.75 % DOI[10.21203/rs.3.rs-23951/v1]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 Activity = 100.0 % PMID[30826188]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 900.0 nM PMID[30738653]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 EC50 = 900.0 nM PMID[30738653]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 100000.0 nM PMID[30738653]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 5000.0 nM PMID[30738653]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 59200.0 nM PMID[30738653]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 IC50 = 1380.0 nM PMID[30798081]
NPT2 Others Unspecified Ratio CC50/IC50 > 1449.0 n.a. PMID[30798081]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 IC50 = 3230.0 nM PMID[30798081]
NPT2 Others Unspecified Ratio CC50/IC50 > 619.0 n.a. PMID[30798081]
NPT26476 ORGANISM Hepatitis A virus Hepatitis A virus IC50 = 35.6 ug.mL-1 PMID[30844608]
NPT2 Others Unspecified CC50 > 1000.0 ug.mL-1 PMID[30844608]
NPT26476 ORGANISM Hepatitis A virus Hepatitis A virus IC50 = 33.5 ug.mL-1 PMID[30844608]
NPT26476 ORGANISM Hepatitis A virus Hepatitis A virus IC50 = 30.6 ug.mL-1 PMID[30844608]
NPT27 Others Unspecified Ratio CC50/IC50 = 80.0 n.a. PMID[30844608]
NPT27 Others Unspecified Ratio CC50/IC50 = 85.0 n.a. PMID[30844608]
NPT27 Others Unspecified Ratio CC50/IC50 = 93.0 n.a. PMID[30844608]
NPT4194 Organism Human adenovirus type 2 Human adenovirus 2 EC50 = 5800.0 nM PMID[31586832]
NPT334 Organism Vaccinia virus Vaccinia virus EC50 > 250000.0 nM PMID[31586832]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 17000.0 nM PMID[31586832]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 EC50 = 2000.0 nM PMID[31586832]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 900.0 nM PMID[31586832]
NPT2 Others Unspecified CC50 > 440000.0 nM PMID[31586832]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 96000.0 nM PMID[31586832]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 1560.0 nM PMID[31586832]
NPT20556 SINGLE PROTEIN Replicase polyprotein 1ab Severe acute respiratory syndrome coronavirus 2 Inhibition = 6.729 % DOI[10.6019/CHEMBL4495564]
NPT20555 ORGANISM SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2 Inhibition = 0.04 % DOI[10.6019/CHEMBL4495565]
NPT20 Organism Candida albicans Candida albicans Inhibition = 4.6 % DOI[10.6019/CHEMBL4296181]
NPT85 Organism Filobasidiella neoformans Cryptococcus neoformans Inhibition = -1.27 % DOI[10.6019/CHEMBL4296181]
NPT19 Organism Escherichia coli Escherichia coli Inhibition = 4.79 % DOI[10.6019/CHEMBL4296181]
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae Inhibition = 6.29 % DOI[10.6019/CHEMBL4296181]
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa Inhibition = 9.14 % DOI[10.6019/CHEMBL4296181]
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii Inhibition = 6.13 % DOI[10.6019/CHEMBL4296181]
NPT2922 Organism Staphylococcus aureus subsp. aureus Staphylococcus aureus subsp. aureus Inhibition = -22.02 % DOI[10.6019/CHEMBL4296181]
NPT20 Organism Candida albicans Candida albicans MIC > 20000.0 nM DOI[10.6019/CHEMBL4296181]
NPT85 Organism Filobasidiella neoformans Cryptococcus neoformans MIC > 20000.0 nM DOI[10.6019/CHEMBL4296181]
NPT19 Organism Escherichia coli Escherichia coli MIC > 20000.0 nM DOI[10.6019/CHEMBL4296181]
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC > 20000.0 nM DOI[10.6019/CHEMBL4296181]
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC > 20000.0 nM DOI[10.6019/CHEMBL4296181]
NPT747 Organism Acinetobacter baumannii Acinetobacter baumannii MIC > 20000.0 nM DOI[10.6019/CHEMBL4296181]
NPT2922 Organism Staphylococcus aureus subsp. aureus Staphylococcus aureus subsp. aureus MIC > 20000.0 nM DOI[10.6019/CHEMBL4296181]
NPT1141 Organism Human herpesvirus 2 Human herpesvirus 2 IC50 = 31000.0 nM PMID[31975590]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 7060.0 nM PMID[32676147]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 42700.0 nM PMID[32676147]
NPT2 Others Unspecified Ratio CC50/EC50 = 916.0 n.a. PMID[32089391]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 1200.0 ug.mL-1 PMID[32089391]
NPT2 Others Unspecified Ratio CC50/EC50 = 86.0 n.a. PMID[32089391]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 EC50 = 12800.0 ug.mL-1 PMID[32089391]
NPT20555 ORGANISM SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2 IC50 > 20000.0 nM DOI[10.6019/CHEMBL4651402]
NPT20555 ORGANISM SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2 IC50 > 19952.62 nM DOI[10.6019/CHEMBL4651402]
NPT2 Others Unspecified Ratio CC50/EC50 = 19.0 n.a. PMID[33479570]
NPT2 Others Unspecified Ratio CC50/EC50 = 265.0 n.a. PMID[33479570]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 22150.0 nM PMID[33479570]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 1600.0 nM PMID[33479570]
NPT190 Organism Human herpesvirus 1 Human herpesvirus 1 IC50 = 27400.0 nM PMID[32961320]
NPT2 Others Unspecified EC50 = 990.0 nM PMID[27933957]
NPT2 Others Unspecified Ratio CC50/EC50 > 300.0 n.a. PMID[27933957]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 4170.0 nM PMID[34124679]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC90 = 30.23 uM PMID[34124679]
NPT2 Others Unspecified Ratio CC50/EC50 > 36.0 n.a. PMID[34124679]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 490.0 nM PMID[33039724]
NPT1749 Organism Human herpesvirus 3 Human herpesvirus 3 EC50 = 23220.0 nM PMID[33039724]

☑ Note for Activity Records:
☉ The quantitative biological activities were primarily integrated from ChEMBL (Version-30) database and were also directly collected from PubMed literature. PubMed PMID was provided as the reference link for each activity record.

  Chemically structural similarity: I. Similar Active Natural Products in NPASS

Top-200 similar NPs were calculated against the active-NP-set (includes 4,3285 NPs with experimentally-derived bioactivity available in NPASS)

Similarity level is defined by Tanimoto coefficient (Tc) between two molecules. Tc lies between [0, 1] where '1' indicates the highest similarity. What is Tanimoto coefficient

●  The left chart: Distribution of similarity level between NPC35410 and all remaining natural products in the NPASS database.
●  The right table: Most similar natural products (Tc>=0.56 or Top200).

Similarity Score Similarity Level Natural Product ID

  Chemically structural similarity: II. Similar Clinical/Approved Drugs

Similarity level is defined by Tanimoto coefficient (Tc) between two molecules.

●  The left chart: Distribution of similarity level between NPC35410 and all drugs/candidates.
●  The right table: Most similar clinical/approved drugs (Tc>=0.56 or Top200).

Similarity Score Similarity Level Drug ID Developmental Stage

  Bioactivity similarity: Similar Natural Products in NPASS

Bioactivity similarity was calculated based on bioactivity descriptors of compounds. The bioactivity descriptors were calculated by a recently developed AI algorithm Chemical Checker (CC) [Nature Biotechnology, 38:1087–1096, 2020; Nature Communications, 12:3932, 2021], which evaluated bioactivity similarities at five levels:
A: chemistry similarity;
B: biological targets similarity;
C: networks similarity;
D: cell-based bioactivity similarity;
E: similarity based on clinical data.

Those 5 categories of CC bioactivity descriptors were calculated and then subjected to manifold projection using UMAP algorithm, to project all NPs on a 2-Dimensional space. The current NP was highlighted with a small circle in the 2-D map. Below figures: left-to-right, A-to-E.

A: chemistry similarity
B: biological targets similarity
C: networks similarity
D: cell-based bioactivity similarity
E: similarity based on clinical data