Organism ID | Organism Name | Taxonomy Level | Family | SuperKingdom | Isolation Part | Collection Location | Collection Time | Reference |
---|---|---|---|---|---|---|---|---|
NPO1797 | Homo sapiens | Species | Hominidae | Eukaryota | urine |
PMID[21543078] |
||
NPO20338 | Mus musculus | Species | Muridae | Eukaryota |
PMID[19425150] |
|||
NPO12011 | Crataegus pinnatifida | Species | Rosaceae | Eukaryota | TCMID* |
Target ID | Target Type | Target Name | Target Organism | Activity Type | Activity Relation | Value | Unit | Reference |
---|---|---|---|---|---|---|---|---|
NPT2945 | Individual Protein | Phospholipase A2 group 1B | Sus scrofa | Activity | = | 2.5 | nM min-1 mg-1 | 9873499 |
NPT79 | Organism | Bacillus subtilis | Bacillus subtilis | IC50 | = | 6830000 | nM | 6802973 |
NPT137 | Cell Line | L1210 | Mus musculus | Activity | < | 15 | % | 16279782 |
NPT783 | Cell Line | MIA PaCa-2 | Homo sapiens | IC50 | = | 10994 | nM | 17944451 |
NPT783 | Cell Line | MIA PaCa-2 | Homo sapiens | IC50 | = | 12994 | nM | 17944451 |
NPT901 | Individual Protein | UDP-glucuronosyltransferase 1-1 | Homo sapiens | Activity | = | 200 | pm/min/mg | 10836148 |
NPT901 | Individual Protein | UDP-glucuronosyltransferase 1-1 | Homo sapiens | Activity | = | 86 | pm/min/mg | 10836148 |
NPT699 | Individual Protein | UDP-glucuronosyltransferase 1-10 | Homo sapiens | Activity | = | 0 | pm/min/mg | 10836148 |
NPT699 | Individual Protein | UDP-glucuronosyltransferase 1-10 | Homo sapiens | Activity | = | 10 | pm/min/mg | 10836148 |
NPT694 | Individual Protein | UDP-glucuronosyltransferase 1-3 | Homo sapiens | Activity | = | 239 | pm/min/mg | 10836148 |
NPT902 | Individual Protein | UDP-glucuronosyltransferase 1A4 | Homo sapiens | Activity | = | 5 | pm/min/mg | 10836148 |
NPT702 | Individual Protein | UDP-glucuronosyltransferase 1-6 | Homo sapiens | Activity | = | 33.5 | pm/min/mg | 10836148 |
NPT702 | Individual Protein | UDP-glucuronosyltransferase 1-6 | Homo sapiens | Activity | = | 17 | pm/min/mg | 10836148 |
NPT903 | Individual Protein | UDP-glucuronosyltransferase 1-7 | Homo sapiens | Activity | = | 28 | pm/min/mg | 10836148 |
NPT695 | Individual Protein | UDP-glucuronosyltransferase 1-8 | Homo sapiens | Activity | = | 287 | pm/min/mg | 10836148 |
NPT695 | Individual Protein | UDP-glucuronosyltransferase 1-8 | Homo sapiens | Activity | = | 215 | pm/min/mg | 10836148 |
NPT700 | Individual Protein | UDP-glucuronosyltransferase 2B10 | Homo sapiens | Activity | = | 0 | pm/min/mg | 10836148 |
NPT704 | Individual Protein | UDP-glucuronosyltransferase 2B15 | Homo sapiens | Activity | = | 73 | pm/min/mg | 10836148 |
NPT904 | Individual Protein | UDP-glucuronosyltransferase 2B17 | Homo sapiens | Activity | = | 4 | pm/min/mg | 10836148 |
NPT701 | Individual Protein | UDP-glucuronosyltransferase 2B4 | Homo sapiens | Activity | = | 0.45 | pm/min/mg | 10836148 |
NPT697 | Individual Protein | UDP-glucuronosyltransferase 2B7 | Homo sapiens | Activity | = | 5 | pm/min/mg | 10836148 |
NPT697 | Individual Protein | UDP-glucuronosyltransferase 2B7 | Homo sapiens | Activity | = | 0 | pm/min/mg | 10836148 |
NPT2 | Others | Unspecified | Ratio | = | 40 | 23473072 | ||
NPT2 | Others | Unspecified | Kd | = | 3000 | nM | 23473072 | |
NPT2 | Others | Unspecified | Kd | = | 123000 | nM | 23473072 | |
NPT2 | Others | Unspecified | Potency | 54482.7 | nM | PubChem BioAssay data set | ||
NPT2 | Others | Unspecified | Potency | 1806.1 | nM | PubChem BioAssay data set | ||
NPT153 | Individual Protein | Androgen Receptor | Homo sapiens | Potency | 25511.2 | nM | PubChem BioAssay data set | |
NPT153 | Individual Protein | Androgen Receptor | Homo sapiens | Potency | 17373.9 | nM | PubChem BioAssay data set | |
NPT2 | Others | Unspecified | Potency | 71248.7 | nM | PubChem BioAssay data set | ||
NPT2 | Others | Unspecified | Potency | 44954.9 | nM | PubChem BioAssay data set | ||
NPT2 | Others | Unspecified | Potency | 61644.8 | nM | PubChem BioAssay data set | ||
NPT2 | Others | Unspecified | Potency | 61130.6 | nM | PubChem BioAssay data set | ||
NPT2 | Others | Unspecified | Potency | 57.1 | nM | PubChem BioAssay data set | ||
NPT153 | Individual Protein | Androgen Receptor | Homo sapiens | Potency | 27535.7 | nM | PubChem BioAssay data set | |
NPT2 | Others | Unspecified | Potency | 56594.8 | nM | PubChem BioAssay data set | ||
NPT2 | Others | Unspecified | Potency | 48557.7 | nM | PubChem BioAssay data set | ||
NPT2 | Others | Unspecified | Potency | 64081.3 | nM | PubChem BioAssay data set | ||
NPT2 | Others | Unspecified | Potency | 50901.6 | nM | PubChem BioAssay data set | ||
NPT2 | Others | Unspecified | Potency | 27535.7 | nM | PubChem BioAssay data set | ||
NPT2 | Others | Unspecified | Potency | 43277.1 | nM | PubChem BioAssay data set | ||
NPT2 | Others | Unspecified | Potency | 63500.4 | nM | PubChem BioAssay data set | ||
NPT2 | Others | Unspecified | Potency | 7994.2 | nM | PubChem BioAssay data set | ||
NPT2 | Others | Unspecified | Potency | 76958.8 | nM | PubChem BioAssay data set | ||
NPT2 | Others | Unspecified | Potency | 27306 | nM | PubChem BioAssay data set | ||
NPT2 | Others | Unspecified | Potency | 12197.2 | nM | PubChem BioAssay data set | ||
NPT2 | Others | Unspecified | FC | = | 3.3 | 13215 | ||
NPT2 | Others | Unspecified | FC | = | 3.37 | 13215 | ||
NPT2 | Others | Unspecified | FC | = | 3.51 | 13215 | ||
NPT2 | Others | Unspecified | FC | = | 3.39 | 13215 | ||
NPT163 | Individual Protein | Nuclear factor NF-kappa-B p105 subunit | Homo sapiens | Potency | 389 | nM | PubChem BioAssay data set | |
NPT2 | Others | Unspecified | Potency | 11395.4 | nM | PubChem BioAssay data set | ||
NPT2 | Others | Unspecified | Potency | 22530.8 | nM | PubChem BioAssay data set |
Similarity level is defined by Tanimoto coefficient (Tc) between two molecules. Tc lies between [0, 1] where '1' indicates the highest similarity. What is Tanimoto coefficient
●  The left chart: Distribution of similarity level between NPC44836 and all remaining natural products in the NPASS database.
●  The right table: Most similar natural products (Tc>=0.56 or Top200).
Similarity Score | Similarity Level | Natural Product ID |
---|---|---|
0.8962 | High Similarity | NPC329358 |
0.8919 | High Similarity | NPC321869 |
0.8824 | High Similarity | NPC70201 |
0.8545 | High Similarity | NPC322735 |
0.8505 | High Similarity | NPC76327 |
0.8468 | Intermediate Similarity | NPC329190 |
0.8131 | Intermediate Similarity | NPC311660 |
0.8056 | Intermediate Similarity | NPC256838 |
0.7857 | Intermediate Similarity | NPC255721 |
0.7788 | Intermediate Similarity | NPC9336 |
0.7759 | Intermediate Similarity | NPC222982 |
0.7717 | Intermediate Similarity | NPC317872 |
0.7586 | Intermediate Similarity | NPC264782 |
0.6891 | Remote Similarity | NPC226914 |
0.6869 | Remote Similarity | NPC100980 |
0.6842 | Remote Similarity | NPC91615 |
0.6765 | Remote Similarity | NPC65517 |
0.6696 | Remote Similarity | NPC29601 |
0.6692 | Remote Similarity | NPC313466 |
0.6692 | Remote Similarity | NPC314278 |
0.6691 | Remote Similarity | NPC316574 |
0.6607 | Remote Similarity | NPC476483 |
0.6594 | Remote Similarity | NPC204156 |
0.6571 | Remote Similarity | NPC204932 |
0.6557 | Remote Similarity | NPC280382 |
0.6538 | Remote Similarity | NPC315632 |
0.6509 | Remote Similarity | NPC270094 |
0.65 | Remote Similarity | NPC37584 |
0.65 | Remote Similarity | NPC215445 |
0.6496 | Remote Similarity | NPC122542 |
0.6449 | Remote Similarity | NPC166667 |
0.6415 | Remote Similarity | NPC4154 |
0.6408 | Remote Similarity | NPC323798 |
0.6403 | Remote Similarity | NPC469828 |
0.6393 | Remote Similarity | NPC172046 |
0.6377 | Remote Similarity | NPC159589 |
0.6357 | Remote Similarity | NPC314252 |
0.6357 | Remote Similarity | NPC47986 |
0.6331 | Remote Similarity | NPC159722 |
0.6331 | Remote Similarity | NPC126637 |
0.6325 | Remote Similarity | NPC125732 |
0.6319 | Remote Similarity | NPC146370 |
0.6312 | Remote Similarity | NPC314113 |
0.6303 | Remote Similarity | NPC178902 |
0.6296 | Remote Similarity | NPC15839 |
0.6283 | Remote Similarity | NPC151764 |
0.6271 | Remote Similarity | NPC155847 |
0.6271 | Remote Similarity | NPC289381 |
0.6268 | Remote Similarity | NPC470090 |
0.6262 | Remote Similarity | NPC307456 |
0.625 | Remote Similarity | NPC473987 |
0.6241 | Remote Similarity | NPC181526 |
0.6202 | Remote Similarity | NPC229353 |
0.6182 | Remote Similarity | NPC33756 |
0.6182 | Remote Similarity | NPC319826 |
0.6182 | Remote Similarity | NPC265146 |
0.6182 | Remote Similarity | NPC124436 |
0.6182 | Remote Similarity | NPC38459 |
0.6167 | Remote Similarity | NPC178681 |
0.6167 | Remote Similarity | NPC68055 |
0.6161 | Remote Similarity | NPC280254 |
0.6154 | Remote Similarity | NPC301702 |
0.6149 | Remote Similarity | NPC40209 |
0.6148 | Remote Similarity | NPC231705 |
0.6132 | Remote Similarity | NPC322285 |
0.6126 | Remote Similarity | NPC248817 |
0.6126 | Remote Similarity | NPC286904 |
0.6126 | Remote Similarity | NPC175313 |
0.6126 | Remote Similarity | NPC150837 |
0.6115 | Remote Similarity | NPC297584 |
0.6111 | Remote Similarity | NPC168750 |
0.6111 | Remote Similarity | NPC471785 |
0.6106 | Remote Similarity | NPC157213 |
0.6106 | Remote Similarity | NPC104216 |
0.6102 | Remote Similarity | NPC107619 |
0.6102 | Remote Similarity | NPC315921 |
0.6099 | Remote Similarity | NPC43218 |
0.6098 | Remote Similarity | NPC142297 |
0.6094 | Remote Similarity | NPC160179 |
0.6078 | Remote Similarity | NPC271732 |
0.6071 | Remote Similarity | NPC197783 |
0.6071 | Remote Similarity | NPC155393 |
0.6069 | Remote Similarity | NPC260601 |
0.605 | Remote Similarity | NPC323726 |
0.6048 | Remote Similarity | NPC96224 |
0.6048 | Remote Similarity | NPC24101 |
0.6048 | Remote Similarity | NPC153690 |
0.6047 | Remote Similarity | NPC147957 |
0.6018 | Remote Similarity | NPC184169 |
0.6018 | Remote Similarity | NPC407 |
0.6018 | Remote Similarity | NPC307235 |
0.6018 | Remote Similarity | NPC23167 |
0.6 | Remote Similarity | NPC47950 |
0.6 | Remote Similarity | NPC277758 |
0.6 | Remote Similarity | NPC312304 |
0.6 | Remote Similarity | NPC288923 |
0.6 | Remote Similarity | NPC290566 |
0.6 | Remote Similarity | NPC145638 |
0.6 | Remote Similarity | NPC258056 |
0.6 | Remote Similarity | NPC300017 |
0.6 | Remote Similarity | NPC300478 |
0.5986 | Remote Similarity | NPC473769 |
0.5985 | Remote Similarity | NPC130931 |
0.5985 | Remote Similarity | NPC150323 |
0.5965 | Remote Similarity | NPC113460 |
0.5965 | Remote Similarity | NPC25493 |
0.5965 | Remote Similarity | NPC27974 |
0.596 | Remote Similarity | NPC36168 |
0.5959 | Remote Similarity | NPC470403 |
0.5959 | Remote Similarity | NPC470394 |
0.5959 | Remote Similarity | NPC470404 |
0.5952 | Remote Similarity | NPC474149 |
0.5948 | Remote Similarity | NPC270547 |
0.5948 | Remote Similarity | NPC45040 |
0.5948 | Remote Similarity | NPC70549 |
0.5946 | Remote Similarity | NPC315829 |
0.5933 | Remote Similarity | NPC264400 |
0.5931 | Remote Similarity | NPC476462 |
0.5929 | Remote Similarity | NPC252149 |
0.5929 | Remote Similarity | NPC208022 |
0.5917 | Remote Similarity | NPC316435 |
0.5913 | Remote Similarity | NPC280347 |
0.5913 | Remote Similarity | NPC318325 |
0.5913 | Remote Similarity | NPC98772 |
0.5913 | Remote Similarity | NPC177420 |
0.5913 | Remote Similarity | NPC123273 |
0.5913 | Remote Similarity | NPC242240 |
0.5913 | Remote Similarity | NPC258219 |
0.5905 | Remote Similarity | NPC66775 |
0.5897 | Remote Similarity | NPC138117 |
0.5897 | Remote Similarity | NPC325292 |
0.5897 | Remote Similarity | NPC181709 |
0.5897 | Remote Similarity | NPC29373 |
0.5896 | Remote Similarity | NPC268348 |
0.5894 | Remote Similarity | NPC184161 |
0.5891 | Remote Similarity | NPC118202 |
0.5886 | Remote Similarity | NPC44161 |
0.5878 | Remote Similarity | NPC470395 |
0.5873 | Remote Similarity | NPC316052 |
0.5871 | Remote Similarity | NPC306366 |
0.587 | Remote Similarity | NPC259098 |
0.587 | Remote Similarity | NPC197680 |
0.5867 | Remote Similarity | NPC144691 |
0.5862 | Remote Similarity | NPC55561 |
0.5862 | Remote Similarity | NPC192 |
0.5859 | Remote Similarity | NPC146422 |
0.5849 | Remote Similarity | NPC301874 |
0.5847 | Remote Similarity | NPC32977 |
0.5847 | Remote Similarity | NPC128062 |
0.5847 | Remote Similarity | NPC81010 |
0.5847 | Remote Similarity | NPC16649 |
0.5847 | Remote Similarity | NPC114325 |
0.5847 | Remote Similarity | NPC151715 |
0.5846 | Remote Similarity | NPC317254 |
0.5839 | Remote Similarity | NPC220523 |
0.5833 | Remote Similarity | NPC475983 |
0.5833 | Remote Similarity | NPC199737 |
0.5828 | Remote Similarity | NPC322283 |
0.5826 | Remote Similarity | NPC19680 |
0.5821 | Remote Similarity | NPC473050 |
0.5821 | Remote Similarity | NPC473051 |
0.5814 | Remote Similarity | NPC309808 |
0.5812 | Remote Similarity | NPC322888 |
0.5812 | Remote Similarity | NPC304541 |
0.5812 | Remote Similarity | NPC204210 |
0.5812 | Remote Similarity | NPC231150 |
0.5812 | Remote Similarity | NPC155908 |
0.5812 | Remote Similarity | NPC306074 |
0.5812 | Remote Similarity | NPC174048 |
0.5806 | Remote Similarity | NPC313362 |
0.5802 | Remote Similarity | NPC106551 |
0.5802 | Remote Similarity | NPC82963 |
0.5802 | Remote Similarity | NPC281686 |
0.5802 | Remote Similarity | NPC188867 |
0.58 | Remote Similarity | NPC257142 |
0.5798 | Remote Similarity | NPC286006 |
0.5798 | Remote Similarity | NPC26244 |
0.5798 | Remote Similarity | NPC313650 |
0.5798 | Remote Similarity | NPC274678 |
0.5798 | Remote Similarity | NPC246679 |
0.5798 | Remote Similarity | NPC257182 |
0.5798 | Remote Similarity | NPC107522 |
0.5796 | Remote Similarity | NPC139506 |
0.5796 | Remote Similarity | NPC292143 |
0.5789 | Remote Similarity | NPC219383 |
0.5786 | Remote Similarity | NPC314473 |
0.5782 | Remote Similarity | NPC60553 |
0.5779 | Remote Similarity | NPC112766 |
0.5776 | Remote Similarity | NPC92689 |
0.5776 | Remote Similarity | NPC78154 |
0.5769 | Remote Similarity | NPC205652 |
0.5769 | Remote Similarity | NPC142599 |
0.5769 | Remote Similarity | NPC470550 |
0.5766 | Remote Similarity | NPC325013 |
0.5766 | Remote Similarity | NPC205946 |
0.5763 | Remote Similarity | NPC210497 |
0.5763 | Remote Similarity | NPC55903 |
0.5763 | Remote Similarity | NPC295295 |
0.5763 | Remote Similarity | NPC94139 |
0.5763 | Remote Similarity | NPC147284 |
Similarity level is defined by Tanimoto coefficient (Tc) between two molecules.
●  The left chart: Distribution of similarity level between NPC44836 and all drugs/candidates.
●  The right table: Most similar clinical/approved drugs (Tc>=0.56 or Top200).
Similarity Score | Similarity Level | Drug ID | Developmental Stage |
---|---|---|---|
0.8505 | High Similarity | NPD9507 | Approved |
0.8468 | Intermediate Similarity | NPD286 | Approved |
0.8108 | Intermediate Similarity | NPD9376 | Approved |
0.7458 | Intermediate Similarity | NPD9342 | Approved |
0.7333 | Intermediate Similarity | NPD9247 | Phase 3 |
0.7333 | Intermediate Similarity | NPD254 | Approved |
0.7293 | Intermediate Similarity | NPD521 | Clinical (unspecified phase) |
0.719 | Intermediate Similarity | NPD313 | Approved |
0.7165 | Intermediate Similarity | NPD9723 | Approved |
0.6984 | Remote Similarity | NPD522 | Approved |
0.697 | Remote Similarity | NPD756 | Suspended |
0.6889 | Remote Similarity | NPD204 | Clinical (unspecified phase) |
0.6869 | Remote Similarity | NPD9087 | Approved |
0.6833 | Remote Similarity | NPD308 | Approved |
0.6765 | Remote Similarity | NPD9088 | Approved |
0.6691 | Remote Similarity | NPD6636 | Phase 3 |
0.6691 | Remote Similarity | NPD9279 | Approved |
0.6667 | Remote Similarity | NPD1158 | Phase 2 |
0.6621 | Remote Similarity | NPD1162 | Approved |
0.6607 | Remote Similarity | NPD1394 | Approved |
0.6597 | Remote Similarity | NPD711 | Discontinued |
0.6594 | Remote Similarity | NPD3391 | Approved |
0.6515 | Remote Similarity | NPD1160 | Phase 2 |
0.6509 | Remote Similarity | NPD9089 | Approved |
0.6471 | Remote Similarity | NPD1393 | Approved |
0.6454 | Remote Similarity | NPD965 | Approved |
0.6443 | Remote Similarity | NPD935 | Clinical (unspecified phase) |
0.6415 | Remote Similarity | NPD9093 | Approved |
0.6408 | Remote Similarity | NPD1196 | Approved |
0.6403 | Remote Similarity | NPD822 | Approved |
0.64 | Remote Similarity | NPD3241 | Phase 2 |
0.6377 | Remote Similarity | NPD471 | Approved |
0.6351 | Remote Similarity | NPD1557 | Discontinued |
0.6338 | Remote Similarity | NPD1195 | Approved |
0.6319 | Remote Similarity | NPD1084 | Clinical (unspecified phase) |
0.6276 | Remote Similarity | NPD1543 | Discontinued |
0.625 | Remote Similarity | NPD9610 | Approved |
0.625 | Remote Similarity | NPD9608 | Approved |
0.625 | Remote Similarity | NPD1314 | Clinical (unspecified phase) |
0.6241 | Remote Similarity | NPD1422 | Approved |
0.6197 | Remote Similarity | NPD7083 | Clinical (unspecified phase) |
0.6182 | Remote Similarity | NPD111 | Approved |
0.6182 | Remote Similarity | NPD9073 | Approved |
0.617 | Remote Similarity | NPD1169 | Approved |
0.6161 | Remote Similarity | NPD9094 | Approved |
0.6154 | Remote Similarity | NPD9277 | Approved |
0.6154 | Remote Similarity | NPD75 | Approved |
0.6148 | Remote Similarity | NPD849 | Approved |
0.6148 | Remote Similarity | NPD850 | Approved |
0.6148 | Remote Similarity | NPD848 | Approved |
0.6129 | Remote Similarity | NPD3251 | Approved |
0.6106 | Remote Similarity | NPD9295 | Approved |
0.6102 | Remote Similarity | NPD9273 | Approved |
0.6096 | Remote Similarity | NPD3141 | Discontinued |
0.6084 | Remote Similarity | NPD9276 | Approved |
0.6084 | Remote Similarity | NPD9274 | Approved |
0.6084 | Remote Similarity | NPD9278 | Suspended |
0.6084 | Remote Similarity | NPD9275 | Approved |
0.6076 | Remote Similarity | NPD1220 | Phase 1 |
0.6071 | Remote Similarity | NPD9694 | Discovery |
0.6069 | Remote Similarity | NPD2241 | Approved |
0.6067 | Remote Similarity | NPD3229 | Phase 2 |
0.6067 | Remote Similarity | NPD5639 | Clinical (unspecified phase) |
0.6063 | Remote Similarity | NPD456 | Approved |
0.6056 | Remote Similarity | NPD5788 | Clinical (unspecified phase) |
0.6054 | Remote Similarity | NPD2114 | Discontinued |
0.6051 | Remote Similarity | NPD1293 | Approved |
0.6027 | Remote Similarity | NPD1835 | Phase 1 |
0.6026 | Remote Similarity | NPD2341 | Discontinued |
0.6017 | Remote Similarity | NPD9070 | Clinical (unspecified phase) |
0.6 | Remote Similarity | NPD457 | Approved |
0.6 | Remote Similarity | NPD9380 | Clinical (unspecified phase) |
0.6 | Remote Similarity | NPD9587 | Clinical (unspecified phase) |
0.6 | Remote Similarity | NPD950 | Clinical (unspecified phase) |
0.5987 | Remote Similarity | NPD3511 | Discontinued |
0.5987 | Remote Similarity | NPD2672 | Discontinued |
0.5985 | Remote Similarity | NPD9272 | Approved |
0.5973 | Remote Similarity | NPD9509 | Clinical (unspecified phase) |
0.5971 | Remote Similarity | NPD9471 | Clinical (unspecified phase) |
0.5963 | Remote Similarity | NPD1221 | Approved |
0.5962 | Remote Similarity | NPD3252 | Approved |
0.5959 | Remote Similarity | NPD5819 | Phase 2 |
0.5939 | Remote Similarity | NPD6045 | Phase 3 |
0.5931 | Remote Similarity | NPD5719 | Approved |
0.5894 | Remote Similarity | NPD1678 | Clinical (unspecified phase) |
0.5891 | Remote Similarity | NPD9618 | Approved |
0.5891 | Remote Similarity | NPD9614 | Approved |
0.5887 | Remote Similarity | NPD1445 | Approved |
0.5887 | Remote Similarity | NPD1444 | Approved |
0.5882 | Remote Similarity | NPD2789 | Approved |
0.5859 | Remote Similarity | NPD9379 | Approved |
0.5859 | Remote Similarity | NPD9377 | Approved |
0.5854 | Remote Similarity | NPD5637 | Discontinued |
0.5852 | Remote Similarity | NPD964 | Approved |
0.5847 | Remote Similarity | NPD9296 | Approved |
0.5847 | Remote Similarity | NPD2934 | Approved |
0.5847 | Remote Similarity | NPD665 | Phase 2 |
0.5847 | Remote Similarity | NPD2933 | Approved |
0.5846 | Remote Similarity | NPD255 | Approved |
0.5846 | Remote Similarity | NPD256 | Approved |
0.5827 | Remote Similarity | NPD9280 | Clinical (unspecified phase) |
0.5821 | Remote Similarity | NPD1981 | Approved |
0.5821 | Remote Similarity | NPD1980 | Approved |
0.5821 | Remote Similarity | NPD1983 | Approved |
0.5817 | Remote Similarity | NPD3296 | Phase 1 |
0.5814 | Remote Similarity | NPD2228 | Approved |
0.5814 | Remote Similarity | NPD2234 | Approved |
0.5814 | Remote Similarity | NPD2229 | Approved |
0.5802 | Remote Similarity | NPD9568 | Approved |
0.5798 | Remote Similarity | NPD2859 | Approved |
0.5798 | Remote Similarity | NPD2860 | Approved |
0.5796 | Remote Similarity | NPD3453 | Discontinued |
0.5789 | Remote Similarity | NPD1633 | Approved |
0.5789 | Remote Similarity | NPD9695 | Approved |
0.5786 | Remote Similarity | NPD3720 | Discontinued |
0.5786 | Remote Similarity | NPD4274 | Approved |
0.5786 | Remote Similarity | NPD4275 | Approved |
0.5769 | Remote Similarity | NPD5599 | Discontinued |
0.5766 | Remote Similarity | NPD6320 | Approved |
0.5762 | Remote Similarity | NPD1159 | Approved |
0.5758 | Remote Similarity | NPD317 | Approved |
0.5758 | Remote Similarity | NPD318 | Approved |
0.5752 | Remote Similarity | NPD1634 | Approved |
0.5748 | Remote Similarity | NPD1792 | Phase 2 |
0.574 | Remote Similarity | NPD3398 | Discontinued |
0.5736 | Remote Similarity | NPD1105 | Clinical (unspecified phase) |
0.5736 | Remote Similarity | NPD181 | Approved |
0.5735 | Remote Similarity | NPD2337 | Clinical (unspecified phase) |
0.5733 | Remote Similarity | NPD2752 | Clinical (unspecified phase) |
0.5731 | Remote Similarity | NPD4740 | Approved |
0.5714 | Remote Similarity | NPD1432 | Clinical (unspecified phase) |
0.5714 | Remote Similarity | NPD3684 | Discontinued |
0.5714 | Remote Similarity | NPD2226 | Clinical (unspecified phase) |
0.5705 | Remote Similarity | NPD9469 | Approved |
0.5705 | Remote Similarity | NPD6283 | Phase 2 |
0.5704 | Remote Similarity | NPD1671 | Clinical (unspecified phase) |
0.5704 | Remote Similarity | NPD1594 | Phase 3 |
0.5704 | Remote Similarity | NPD1595 | Approved |
0.5702 | Remote Similarity | NPD9097 | Approved |
0.5702 | Remote Similarity | NPD9096 | Approved |
0.5702 | Remote Similarity | NPD68 | Approved |
0.5702 | Remote Similarity | NPD9095 | Approved |
0.5677 | Remote Similarity | NPD4255 | Phase 1 |
0.5677 | Remote Similarity | NPD2366 | Approved |
0.5677 | Remote Similarity | NPD6913 | Approved |
0.5677 | Remote Similarity | NPD1187 | Discontinued |
0.5677 | Remote Similarity | NPD3778 | Approved |
0.5669 | Remote Similarity | NPD3556 | Approved |
0.5669 | Remote Similarity | NPD3558 | Approved |
0.5669 | Remote Similarity | NPD3560 | Approved |
0.5669 | Remote Similarity | NPD3559 | Clinical (unspecified phase) |
0.5669 | Remote Similarity | NPD3557 | Approved |
0.5667 | Remote Similarity | NPD844 | Approved |
0.5667 | Remote Similarity | NPD1305 | Clinical (unspecified phase) |
0.5658 | Remote Similarity | NPD1405 | Approved |
0.5656 | Remote Similarity | NPD3020 | Approved |
0.5652 | Remote Similarity | NPD1839 | Phase 1 |
0.5649 | Remote Similarity | NPD5811 | Approved |
0.5649 | Remote Similarity | NPD1791 | Approved |
0.5649 | Remote Similarity | NPD1793 | Approved |
0.5646 | Remote Similarity | NPD7753 | Approved |
0.5646 | Remote Similarity | NPD7752 | Approved |
0.5643 | Remote Similarity | NPD9701 | Discontinued |
0.5641 | Remote Similarity | NPD3784 | Discontinued |
0.5639 | Remote Similarity | NPD16 | Approved |
0.5639 | Remote Similarity | NPD9615 | Approved |
0.5639 | Remote Similarity | NPD856 | Approved |
0.5639 | Remote Similarity | NPD9613 | Approved |
0.5639 | Remote Similarity | NPD9616 | Approved |
0.5634 | Remote Similarity | NPD864 | Approved |
0.5634 | Remote Similarity | NPD2322 | Discovery |
0.5634 | Remote Similarity | NPD865 | Approved |
0.563 | Remote Similarity | NPD845 | Approved |
0.563 | Remote Similarity | NPD1525 | Approved |
0.5625 | Remote Similarity | NPD2791 | Discontinued |
0.5621 | Remote Similarity | NPD3627 | Approved |
0.562 | Remote Similarity | NPD288 | Approved |
0.5617 | Remote Similarity | NPD1913 | Phase 1 |
0.5614 | Remote Similarity | NPD7617 | Discontinued |
0.5613 | Remote Similarity | NPD948 | Phase 3 |
0.5613 | Remote Similarity | NPD5617 | Suspended |
0.561 | Remote Similarity | NPD1242 | Phase 1 |
0.561 | Remote Similarity | NPD289 | Clinical (unspecified phase) |
0.561 | Remote Similarity | NPD190 | Phase 1 |
0.5608 | Remote Similarity | NPD4598 | Approved |
0.5608 | Remote Similarity | NPD4597 | Approved |
0.56 | Remote Similarity | NPD1622 | Discontinued |
PubChem CID   | 980 |
ChEMBL   | CHEMBL14130 |
ZINC   |
Molecular Weight:   | 139.03 |
ALogP:   | 0.1998 |
MLogP:   | 1.68 |
XLogP:   | 1.72 |
# Rotatable Bonds:   | 3 |
Polar Surface Area:   | 63.37 |
# H-Bond Aceptor:   | 0 |
# H-Bond Donor:   | 1 |
# Rings:   | 1 |
# Heavy Atoms:   | 10 |