Natural Product: NPC43218

Natural Product ID:  NPC43218
Common Name:   2-Amino-3-Hydroxybenzoic Acid
IUPAC Name:   2-amino-3-hydroxybenzoic acid
Synonyms:   3-Hydroxyanthranilic Acid
Molecular Formula:   C7H7NO3
Standard InCHIKey:  WJXSWCUQABXPFS-UHFFFAOYSA-N
Standard InCHI:  InChI=1S/C7H7NO3/c8-6-4(7(10)11)2-1-3-5(6)9/h1-3,9H,8H2,(H,10,11)
Canonical SMILES:  OC(=O)c1cccc(c1N)O
First Find Year:  
Max Developmental Stage:  
Synthetic Gene Cluster:   ;

  Species Source

Organism ID Organism Name Taxonomy Level Family SuperKingdom Isolation Part Collection Location Collection Time Reference
NPO1797 Homo sapiens Species Hominidae Eukaryota urine Geigy Scientific Tables, 8th Rev edition. Edited by C. Lentner, West Cadwell, N.J.: Medical education Div., Ciba-Geigy Corp., Basel, Switzerland c1981-1992.
NPO1797 Homo sapiens Species Hominidae Eukaryota PMID[11392499]
NPO1797 Homo sapiens Species Hominidae Eukaryota blood PMID[8634758]
NPO20338 Mus musculus Species Muridae Eukaryota PMID[22711758]
NPO23175 Streptomyces antibioticus Species Streptomycetaceae Bacteria StreptomeDB*

  Biological Activity

Target ID Target Type Target Name Target Organism Activity Type Activity Relation Value Unit Reference
NPT2 Others Unspecified Activity = 1.7 ug/ml 18003900
NPT2 Others Unspecified Activity = 1.8 ug/ml 18003900
NPT2 Others Unspecified Activity = 0.001 ug/ml 18003900
NPT2 Others Unspecified Activity = 29.7 ug/ml 18003900
NPT2 Others Unspecified Activity = 0.002 ug/ml 18003900
NPT2 Others Unspecified Activity = 6.7 ug/ml 18003900
NPT2 Others Unspecified Activity = 11.5 ug/ml 18003900
NPT2 Others Unspecified Activity < 0.1 ug/ml 18003900
NPT2 Others Unspecified Activity = 1.15 ug/ml 18003900
NPT2 Others Unspecified Activity = 3.24 ug/ml 18003900
NPT2 Others Unspecified Activity = 4.3 ug/ml 18003900
NPT2 Others Unspecified Activity = 14.9 ug/ml 18003900
NPT2 Others Unspecified Activity = 2.37 ug/ml 18003900
NPT2 Others Unspecified Activity = 4.88 ug/ml 18003900
NPT2 Others Unspecified Activity = 7.77 ug/ml 18003900
NPT32 Organism Mus musculus Mus musculus Activity = 155000 18003900
NPT32 Organism Mus musculus Mus musculus Activity = 0.000141 ug/ml 18003900
NPT32 Organism Mus musculus Mus musculus Activity = 6.60E-05 ug/ml 18003900
NPT32 Organism Mus musculus Mus musculus Activity = 84000 18003900
NPT32 Organism Mus musculus Mus musculus Activity = 0.000153 ug/ml 18003900
NPT32 Organism Mus musculus Mus musculus Activity = 8.80E-05 ug/ml 18003900
NPT32 Organism Mus musculus Mus musculus Activity = 58000 18003900
NPT32 Organism Mus musculus Mus musculus Activity = 0.000144 ug/ml 18003900
NPT32 Organism Mus musculus Mus musculus Activity = 9.10E-05 ug/ml 18003900
NPT32 Organism Mus musculus Mus musculus Activity = 190000 18003900
NPT32 Organism Mus musculus Mus musculus Activity = 0.000219 ug/ml 18003900
NPT32 Organism Mus musculus Mus musculus Activity = 0.000147 ug/ml 18003900
NPT32 Organism Mus musculus Mus musculus Activity = 11000 18003900
NPT32 Organism Mus musculus Mus musculus Activity < 1.00E-05 ug/ml 18003900
NPT2 Others Unspecified IC50 = 7180 nM PubChem BioAssay data set
NPT532 Individual Protein Lysine-specific demethylase 4A Homo sapiens Potency 56234.1 nM PubChem BioAssay data set
NPT152 Individual Protein Nuclear factor erythroid 2-related factor 2 Homo sapiens Potency 20596.2 nM PubChem BioAssay data set
NPT2865 Individual Protein Glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase Plasmodium berghei IC50 = 1440 nM PubChem BioAssay data set
NPT4 Individual Protein Large T antigen Simian virus 40 IC50 20090 nM PubChem BioAssay data set
NPT2866 Individual Protein Replicative DNA helicase Mycobacterium tuberculosis AC50 > 380000 nM PubChem BioAssay data set
NPT2867 Individual Protein Protein RecA Mycobacterium tuberculosis EC50 = 5430 nM PubChem BioAssay data set
NPT905 Individual Protein Glucose-6-phosphate 1-dehydrogenase Homo sapiens IC50 = 24000 nM PubChem BioAssay data set
NPT8 Individual Protein DNA polymerase iota Homo sapiens Potency 39810.7 nM PubChem BioAssay data set
NPT199 Individual Protein DNA polymerase kappa Homo sapiens Potency 56234.1 nM PubChem BioAssay data set
NPT2865 Individual Protein Glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase Plasmodium berghei IC50 > 80000 nM PubChem BioAssay data set
NPT2866 Individual Protein Replicative DNA helicase Mycobacterium tuberculosis AC50 = 27170 nM PubChem BioAssay data set
NPT2865 Individual Protein Glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase Plasmodium berghei IC50 = 40900 nM PubChem BioAssay data set
NPT7 Individual Protein Thioredoxin reductase 1, cytoplasmic Rattus norvegicus Potency 79432.8 nM PubChem BioAssay data set
NPT861 Individual Protein Isocitrate dehydrogenase [NADP] cytoplasmic Homo sapiens Potency 50118.7 nM PubChem BioAssay data set
NPT100 Individual Protein Glutaminase kidney isoform, mitochondrial Homo sapiens Potency 35481.3 nM PubChem BioAssay data set
NPT2 Others Unspecified Potency 29092.9 nM PubChem BioAssay data set
NPT1226 Individual Protein Caspase-7 Homo sapiens AC50 6140 nM PubChem BioAssay data set
NPT867 Individual Protein Caspase-6 Homo sapiens AC50 1590 nM PubChem BioAssay data set
NPT2265 Individual Protein Caspase-9 Homo sapiens AC50 70000 nM PubChem BioAssay data set
NPT2 Others Unspecified Potency 7079.5 nM PubChem BioAssay data set

  Similar Natural Products in NPASS

Similarity level is defined by Tanimoto coefficient (Tc) between two molecules. Tc lies between [0, 1] where '1' indicates the highest similarity. What is Tanimoto coefficient

●  The left chart: Distribution of similarity level between NPC43218 and all remaining natural products in the NPASS database.
●  The right table: Most similar natural products (Tc>=0.56 or Top200).

Similarity Score Similarity Level Natural Product ID
0.8936 High Similarity NPC241392
0.8321 Intermediate Similarity NPC130931
0.8298 Intermediate Similarity NPC314252
0.8276 Intermediate Similarity NPC315829
0.8169 Intermediate Similarity NPC181526
0.7925 Intermediate Similarity NPC8467
0.7888 Intermediate Similarity NPC98416
0.7778 Intermediate Similarity NPC316574
0.7687 Intermediate Similarity NPC301702
0.7656 Intermediate Similarity NPC187913
0.763 Intermediate Similarity NPC229353
0.758 Intermediate Similarity NPC257763
0.7569 Intermediate Similarity NPC253476
0.7554 Intermediate Similarity NPC226794
0.7518 Intermediate Similarity NPC150323
0.7465 Intermediate Similarity NPC122235
0.7415 Intermediate Similarity NPC159722
0.7407 Intermediate Similarity NPC160179
0.7394 Intermediate Similarity NPC72473
0.7394 Intermediate Similarity NPC58827
0.7394 Intermediate Similarity NPC307437
0.7383 Intermediate Similarity NPC43477
0.7365 Intermediate Similarity NPC181527
0.7237 Intermediate Similarity NPC323798
0.7222 Intermediate Similarity NPC127362
0.7206 Intermediate Similarity NPC81808
0.7186 Intermediate Similarity NPC474815
0.7172 Intermediate Similarity NPC477432
0.7143 Intermediate Similarity NPC259678
0.7134 Intermediate Similarity NPC471778
0.7132 Intermediate Similarity NPC98543
0.7115 Intermediate Similarity NPC144691
0.711 Intermediate Similarity NPC144381
0.7101 Intermediate Similarity NPC312800
0.7068 Intermediate Similarity NPC34715
0.7052 Intermediate Similarity NPC18890
0.705 Intermediate Similarity NPC160199
0.7047 Intermediate Similarity NPC173295
0.7045 Intermediate Similarity NPC163734
0.7037 Intermediate Similarity NPC475983
0.7032 Intermediate Similarity NPC146370
0.7023 Intermediate Similarity NPC311660
0.7014 Intermediate Similarity NPC205946
0.6993 Remote Similarity NPC13696
0.6978 Remote Similarity NPC281686
0.6978 Remote Similarity NPC106551
0.6978 Remote Similarity NPC188867
0.6974 Remote Similarity NPC238108
0.6971 Remote Similarity NPC92803
0.6966 Remote Similarity NPC314278
0.695 Remote Similarity NPC156654
0.694 Remote Similarity NPC29883
0.6929 Remote Similarity NPC240664
0.6901 Remote Similarity NPC260837
0.689 Remote Similarity NPC204867
0.6889 Remote Similarity NPC100551
0.6886 Remote Similarity NPC112336
0.6886 Remote Similarity NPC474814
0.6866 Remote Similarity NPC184658
0.6853 Remote Similarity NPC165197
0.6835 Remote Similarity NPC163154
0.6831 Remote Similarity NPC239697
0.6824 Remote Similarity NPC194562
0.6824 Remote Similarity NPC9475
0.6816 Remote Similarity NPC170333
0.6806 Remote Similarity NPC25168
0.6803 Remote Similarity NPC321561
0.6802 Remote Similarity NPC270301
0.6797 Remote Similarity NPC238412
0.6786 Remote Similarity NPC222982
0.6786 Remote Similarity NPC240163
0.6779 Remote Similarity NPC314098
0.6778 Remote Similarity NPC316282
0.6768 Remote Similarity NPC93653
0.6767 Remote Similarity NPC13426
0.6759 Remote Similarity NPC297193
0.6759 Remote Similarity NPC46634
0.6757 Remote Similarity NPC145888
0.6757 Remote Similarity NPC16031
0.6757 Remote Similarity NPC161593
0.675 Remote Similarity NPC264400
0.6741 Remote Similarity NPC317592
0.6727 Remote Similarity NPC199737
0.6712 Remote Similarity NPC477153
0.671 Remote Similarity NPC316202
0.6705 Remote Similarity NPC197335
0.6705 Remote Similarity NPC472163
0.6704 Remote Similarity NPC230403
0.6692 Remote Similarity NPC257182
0.6691 Remote Similarity NPC172170
0.669 Remote Similarity NPC125252
0.669 Remote Similarity NPC27581
0.669 Remote Similarity NPC269414
0.6685 Remote Similarity NPC90229
0.6667 Remote Similarity NPC314659
0.6667 Remote Similarity NPC161304
0.6667 Remote Similarity NPC117794
0.6645 Remote Similarity NPC242933
0.6644 Remote Similarity NPC225710
0.6643 Remote Similarity NPC317784
0.6643 Remote Similarity NPC142638
0.6624 Remote Similarity NPC314287
0.6622 Remote Similarity NPC472592
0.662 Remote Similarity NPC108288
0.6619 Remote Similarity NPC228609
0.6617 Remote Similarity NPC52472
0.6599 Remote Similarity NPC275145
0.6597 Remote Similarity NPC184579
0.6597 Remote Similarity NPC233165
0.6597 Remote Similarity NPC319950
0.6594 Remote Similarity NPC255721
0.6593 Remote Similarity NPC93831
0.6593 Remote Similarity NPC41488
0.6591 Remote Similarity NPC132751
0.6587 Remote Similarity NPC189116
0.6579 Remote Similarity NPC88667
0.6573 Remote Similarity NPC150919
0.6573 Remote Similarity NPC28169
0.6571 Remote Similarity NPC231717
0.6569 Remote Similarity NPC226699
0.6569 Remote Similarity NPC141523
0.6569 Remote Similarity NPC303264
0.6562 Remote Similarity NPC62765
0.6561 Remote Similarity NPC477825
0.6558 Remote Similarity NPC122542
0.6557 Remote Similarity NPC218733
0.6557 Remote Similarity NPC138615
0.6557 Remote Similarity NPC265642
0.6557 Remote Similarity NPC132874
0.6554 Remote Similarity NPC288854
0.6554 Remote Similarity NPC87391
0.6549 Remote Similarity NPC278102
0.6544 Remote Similarity NPC219913
0.6541 Remote Similarity NPC245561
0.6538 Remote Similarity NPC47986
0.6533 Remote Similarity NPC71525
0.6533 Remote Similarity NPC158654
0.6532 Remote Similarity NPC315631
0.6531 Remote Similarity NPC68167
0.6528 Remote Similarity NPC41567
0.6526 Remote Similarity NPC474366
0.6525 Remote Similarity NPC211421
0.6525 Remote Similarity NPC223004
0.6522 Remote Similarity NPC224584
0.6513 Remote Similarity NPC313466
0.6512 Remote Similarity NPC303225
0.651 Remote Similarity NPC287473
0.6509 Remote Similarity NPC182131
0.6507 Remote Similarity NPC326079
0.6507 Remote Similarity NPC159760
0.6507 Remote Similarity NPC178395
0.6507 Remote Similarity NPC222876
0.6507 Remote Similarity NPC301987
0.6507 Remote Similarity NPC35856
0.6507 Remote Similarity NPC272454
0.6507 Remote Similarity NPC292665
0.6507 Remote Similarity NPC115188
0.6507 Remote Similarity NPC244994
0.6507 Remote Similarity NPC179092
0.6507 Remote Similarity NPC26433
0.6506 Remote Similarity NPC301163
0.6503 Remote Similarity NPC131192
0.6503 Remote Similarity NPC128825
0.65 Remote Similarity NPC70340
0.6496 Remote Similarity NPC6984
0.6493 Remote Similarity NPC70201
0.6492 Remote Similarity NPC218303
0.6483 Remote Similarity NPC232178
0.6479 Remote Similarity NPC197513
0.6475 Remote Similarity NPC95172
0.6471 Remote Similarity NPC256838
0.6467 Remote Similarity NPC305717
0.6467 Remote Similarity NPC27904
0.6463 Remote Similarity NPC142577
0.6463 Remote Similarity NPC198336
0.6458 Remote Similarity NPC477826
0.6458 Remote Similarity NPC477827
0.6457 Remote Similarity NPC298320
0.6457 Remote Similarity NPC283810
0.6455 Remote Similarity NPC212123
0.6449 Remote Similarity NPC37584
0.6447 Remote Similarity NPC226855
0.6447 Remote Similarity NPC94810
0.6444 Remote Similarity NPC94343
0.6443 Remote Similarity NPC145134
0.644 Remote Similarity NPC309845
0.6439 Remote Similarity NPC246679
0.6439 Remote Similarity NPC61944
0.6438 Remote Similarity NPC7151
0.6438 Remote Similarity NPC206778
0.6438 Remote Similarity NPC216297
0.6438 Remote Similarity NPC285829
0.6438 Remote Similarity NPC473662
0.6436 Remote Similarity NPC163829
0.6436 Remote Similarity NPC133156
0.6429 Remote Similarity NPC222084
0.6424 Remote Similarity NPC214620
0.6424 Remote Similarity NPC209959
0.6423 Remote Similarity NPC13495
0.642 Remote Similarity NPC300596

  Similar Clinical/Approved Drugs

Similarity level is defined by Tanimoto coefficient (Tc) between two molecules.

●  The left chart: Distribution of similarity level between NPC43218 and all drugs/candidates.
●  The right table: Most similar clinical/approved drugs (Tc>=0.56 or Top200).

Similarity Score Similarity Level Drug ID Developmental Stage
0.8255 Intermediate Similarity NPD2672 Discontinued
0.8188 Intermediate Similarity NPD3684 Discontinued
0.78 Intermediate Similarity NPD9509 Clinical (unspecified phase)
0.7778 Intermediate Similarity NPD9279 Approved
0.7687 Intermediate Similarity NPD75 Approved
0.7687 Intermediate Similarity NPD9277 Approved
0.7619 Intermediate Similarity NPD9278 Suspended
0.7619 Intermediate Similarity NPD9275 Approved
0.7619 Intermediate Similarity NPD9274 Approved
0.7619 Intermediate Similarity NPD9276 Approved
0.7518 Intermediate Similarity NPD9272 Approved
0.75 Intermediate Similarity NPD1574 Approved
0.7284 Intermediate Similarity NPD2821 Approved
0.7237 Intermediate Similarity NPD1196 Approved
0.7219 Intermediate Similarity NPD1189 Approved
0.7171 Intermediate Similarity NPD1625 Approved
0.7171 Intermediate Similarity NPD1195 Approved
0.716 Intermediate Similarity NPD3253 Clinical (unspecified phase)
0.7111 Intermediate Similarity NPD9508 Approved
0.7097 Intermediate Similarity NPD1543 Discontinued
0.7083 Intermediate Similarity NPD1593 Approved
0.7073 Intermediate Similarity NPD2681 Approved
0.7073 Intermediate Similarity NPD2680 Approved
0.7048 Intermediate Similarity NPD1220 Phase 1
0.7029 Intermediate Similarity NPD255 Approved
0.7029 Intermediate Similarity NPD256 Approved
0.6978 Remote Similarity NPD9568 Approved
0.6954 Remote Similarity NPD1532 Approved
0.6943 Remote Similarity NPD4888 Discontinued
0.694 Remote Similarity NPD9265 Clinical (unspecified phase)
0.6923 Remote Similarity NPD1221 Approved
0.6908 Remote Similarity NPD1626 Approved
0.689 Remote Similarity NPD955 Approved
0.6889 Remote Similarity NPD74 Approved
0.6889 Remote Similarity NPD9266 Approved
0.6855 Remote Similarity NPD1230 Approved
0.6853 Remote Similarity NPD9693 Approved
0.6853 Remote Similarity NPD9692 Approved
0.6821 Remote Similarity NPD9468 Clinical (unspecified phase)
0.6821 Remote Similarity NPD7546 Discontinued
0.6815 Remote Similarity NPD9263 Approved
0.6815 Remote Similarity NPD9267 Approved
0.6815 Remote Similarity NPD9264 Approved
0.6803 Remote Similarity NPD257 Approved
0.6803 Remote Similarity NPD258 Approved
0.6774 Remote Similarity NPD168 Phase 1
0.6774 Remote Similarity NPD167 Phase 2
0.6757 Remote Similarity NPD9569 Approved
0.6755 Remote Similarity NPD1531 Approved
0.675 Remote Similarity NPD711 Discontinued
0.6735 Remote Similarity NPD553 Approved
0.6735 Remote Similarity NPD552 Approved
0.6735 Remote Similarity NPD9567 Approved
0.6712 Remote Similarity NPD182 Clinical (unspecified phase)
0.671 Remote Similarity NPD9477 Approved
0.6707 Remote Similarity NPD1559 Discontinued
0.6685 Remote Similarity NPD7071 Clinical (unspecified phase)
0.6667 Remote Similarity NPD2361 Approved
0.6644 Remote Similarity NPD9269 Phase 2
0.6627 Remote Similarity NPD1839 Phase 1
0.662 Remote Similarity NPD405 Clinical (unspecified phase)
0.6608 Remote Similarity NPD2359 Approved
0.6597 Remote Similarity NPD9268 Approved
0.6588 Remote Similarity NPD1913 Phase 1
0.6584 Remote Similarity NPD2737 Clinical (unspecified phase)
0.6579 Remote Similarity NPD259 Phase 1
0.6568 Remote Similarity NPD2249 Approved
0.6568 Remote Similarity NPD2247 Approved
0.6562 Remote Similarity NPD9256 Approved
0.6562 Remote Similarity NPD9258 Approved
0.6561 Remote Similarity NPD6414 Clinical (unspecified phase)
0.6556 Remote Similarity NPD9537 Phase 1
0.6556 Remote Similarity NPD9536 Phase 1
0.6548 Remote Similarity NPD1168 Approved
0.6545 Remote Similarity NPD3812 Clinical (unspecified phase)
0.6536 Remote Similarity NPD826 Approved
0.6536 Remote Similarity NPD825 Approved
0.6536 Remote Similarity NPD5928 Phase 1
0.6527 Remote Similarity NPD1210 Approved
0.6524 Remote Similarity NPD1514 Discontinued
0.6519 Remote Similarity NPD9261 Approved
0.6503 Remote Similarity NPD9493 Approved
0.6494 Remote Similarity NPD275 Approved
0.6494 Remote Similarity NPD274 Approved
0.6494 Remote Similarity NPD555 Phase 2
0.6485 Remote Similarity NPD2836 Approved
0.6485 Remote Similarity NPD2366 Approved
0.6479 Remote Similarity NPD9281 Approved
0.6478 Remote Similarity NPD5819 Phase 2
0.6463 Remote Similarity NPD3455 Phase 2
0.6463 Remote Similarity NPD3229 Phase 2
0.6454 Remote Similarity NPD181 Approved
0.6436 Remote Similarity NPD4456 Clinical (unspecified phase)
0.6433 Remote Similarity NPD9570 Approved
0.6421 Remote Similarity NPD4082 Approved
0.6414 Remote Similarity NPD9545 Approved
0.6398 Remote Similarity NPD6884 Clinical (unspecified phase)
0.6378 Remote Similarity NPD5197 Approved
0.6378 Remote Similarity NPD5196 Approved
0.6378 Remote Similarity NPD5194 Approved
0.6374 Remote Similarity NPD5937 Approved
0.6369 Remote Similarity NPD3170 Approved
0.6369 Remote Similarity NPD1110 Approved
0.6369 Remote Similarity NPD1109 Approved
0.6368 Remote Similarity NPD4596 Phase 1
0.6364 Remote Similarity NPD9618 Approved
0.6364 Remote Similarity NPD5445 Approved
0.6364 Remote Similarity NPD9614 Approved
0.6354 Remote Similarity NPD5860 Discontinued
0.6337 Remote Similarity NPD1161 Approved
0.6335 Remote Similarity NPD4022 Approved
0.6335 Remote Similarity NPD3472 Approved
0.6333 Remote Similarity NPD196 Phase 1
0.6324 Remote Similarity NPD6161 Approved
0.6324 Remote Similarity NPD6162 Approved
0.6322 Remote Similarity NPD7449 Clinical (unspecified phase)
0.6321 Remote Similarity NPD4493 Discontinued
0.6321 Remote Similarity NPD1945 Phase 1
0.6319 Remote Similarity NPD4161 Discontinued
0.6319 Remote Similarity NPD9342 Approved
0.6301 Remote Similarity NPD1759 Phase 1
0.6296 Remote Similarity NPD7597 Clinical (unspecified phase)
0.6292 Remote Similarity NPD1891 Discontinued
0.6287 Remote Similarity NPD1211 Clinical (unspecified phase)
0.6287 Remote Similarity NPD1208 Approved
0.6286 Remote Similarity NPD476 Approved
0.6282 Remote Similarity NPD9694 Discovery
0.6269 Remote Similarity NPD3372 Discontinued
0.6269 Remote Similarity NPD3893 Discontinued
0.6267 Remote Similarity NPD661 Approved
0.6267 Remote Similarity NPD657 Approved
0.6267 Remote Similarity NPD660 Approved
0.6267 Remote Similarity NPD655 Approved
0.6265 Remote Similarity NPD5086 Approved
0.6264 Remote Similarity NPD2248 Approved
0.6264 Remote Similarity NPD2246 Approved
0.6258 Remote Similarity NPD520 Approved
0.625 Remote Similarity NPD9259 Approved
0.625 Remote Similarity NPD1170 Approved
0.625 Remote Similarity NPD9257 Approved
0.6237 Remote Similarity NPD5195 Discontinued
0.6235 Remote Similarity NPD9487 Approved
0.6233 Remote Similarity NPD1758 Phase 1
0.6231 Remote Similarity NPD3783 Clinical (unspecified phase)
0.6209 Remote Similarity NPD2792 Approved
0.6209 Remote Similarity NPD1898 Discontinued
0.6205 Remote Similarity NPD4492 Approved
0.6205 Remote Similarity NPD4494 Approved
0.6205 Remote Similarity NPD3888 Discontinued
0.6203 Remote Similarity NPD6636 Phase 3
0.6203 Remote Similarity NPD4668 Phase 2
0.6194 Remote Similarity NPD9471 Clinical (unspecified phase)
0.6184 Remote Similarity NPD1470 Approved
0.6184 Remote Similarity NPD1164 Approved
0.6178 Remote Similarity NPD447 Suspended
0.6178 Remote Similarity NPD1294 Discontinued
0.6178 Remote Similarity NPD230 Phase 1
0.6176 Remote Similarity NPD4311 Approved
0.6173 Remote Similarity NPD4455 Discontinued
0.617 Remote Similarity NPD5608 Approved
0.617 Remote Similarity NPD5609 Approved
0.6166 Remote Similarity NPD2907 Approved
0.6166 Remote Similarity NPD2906 Approved
0.6163 Remote Similarity NPD3252 Approved
0.6159 Remote Similarity NPD1755 Approved
0.6158 Remote Similarity NPD956 Clinical (unspecified phase)
0.6154 Remote Similarity NPD1527 Phase 2
0.6154 Remote Similarity NPD4515 Suspended
0.615 Remote Similarity NPD5433 Clinical (unspecified phase)
0.615 Remote Similarity NPD4979 Clinical (unspecified phase)
0.6149 Remote Similarity NPD1293 Approved
0.6145 Remote Similarity NPD5637 Discontinued
0.6144 Remote Similarity NPD701 Approved
0.6144 Remote Similarity NPD698 Approved
0.6138 Remote Similarity NPD2339 Phase 3
0.6136 Remote Similarity NPD7324 Discontinued
0.6133 Remote Similarity NPD1201 Approved
0.6129 Remote Similarity NPD3136 Phase 2
0.6129 Remote Similarity NPD9718 Approved
0.6125 Remote Similarity NPD1519 Approved
0.6125 Remote Similarity NPD1537 Approved
0.6125 Remote Similarity NPD1538 Phase 1
0.6122 Remote Similarity NPD9615 Approved
0.6122 Remote Similarity NPD9616 Approved
0.6122 Remote Similarity NPD9613 Approved
0.6115 Remote Similarity NPD9610 Approved
0.6115 Remote Similarity NPD9608 Approved
0.6111 Remote Similarity NPD9377 Approved
0.6111 Remote Similarity NPD9379 Approved
0.6104 Remote Similarity NPD656 Approved
0.6104 Remote Similarity NPD663 Approved
0.6104 Remote Similarity NPD659 Approved
0.6104 Remote Similarity NPD662 Approved
0.6104 Remote Similarity NPD658 Approved
0.6102 Remote Similarity NPD1544 Phase 1
0.6101 Remote Similarity NPD2670 Approved
0.6099 Remote Similarity NPD9507 Approved
0.6096 Remote Similarity NPD6722 Clinical (unspecified phase)
0.6094 Remote Similarity NPD4467 Phase 2
0.6094 Remote Similarity NPD4465 Phase 2

Structure

External Identifiers

PubChem CID   86
ChEMBL   CHEMBL445304
ZINC  

Physicochemical Properties

Molecular Weight:  153.04
ALogP:  -1.45
MLogP:  1.79
XLogP:  0.898
# Rotatable Bonds:  4
Polar Surface Area:  83.55
# H-Bond Aceptor:  3
# H-Bond Donor:  3
# Rings:  1
# Heavy Atoms:  11

Download Data

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General Info & Identifiers & Properties  
Structure MOL file  
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Biological Activities  
Similar NPs/Drugs