Drug Information

Drug ID:  NPD1210
Drug Name:  Meclofenamic Acid
Molecular Formula:  C14H11Cl2NO2
Canonical SMILES:  OC(=O)c1ccccc1Nc1c(Cl)ccc(c1Cl)C
Standard InCHI:  InChI=1S/C14H11Cl2NO2/c1-8-6-7-10(15)13(12(8)16)17-11-5-3-2-4-9(11)14(18)19/h2-7,17H,1H3,(H,18,19)
Standard InCHIKey:  SBDNJUWAMKYJOX-UHFFFAOYSA-N
Max Developmental Stage:  Approved
Max Developmental Stage Source:  TTD; ChEMBL; IUPHAR/BPS

  Structural Similarity Between NPASS Natural Products and NPD1210

Similarity level is defined by Tanimoto coefficient (Tc) between two molecules. Tc lies between [0, 1] where '1' indicates the highest similarity. What is Tanimoto coefficient
Tanimoto coefficient is calculated based on PubChem 881-bit substructure fingerprints.


  Similar Natural Products

High Similarity Level: Tc>=0.85; Intermediate Similarity Level: 0.7 <= Tc < 0.85; Remote Similarity Level: 0.65 <= Tc < 0.7

Similarity Level Similarity Score Natural Product ID
Intermediate Similarity 0.8079 NPC253476
Intermediate Similarity 0.7771 NPC43477
Intermediate Similarity 0.7568 NPC130931
Intermediate Similarity 0.7564 NPC173295
Intermediate Similarity 0.7485 NPC182131
Intermediate Similarity 0.7255 NPC226794
Intermediate Similarity 0.72 NPC229353
Intermediate Similarity 0.716 NPC242933
Intermediate Similarity 0.7134 NPC194562
Intermediate Similarity 0.7127 NPC470317
Intermediate Similarity 0.7126 NPC300596
Intermediate Similarity 0.7126 NPC237649
Intermediate Similarity 0.7099 NPC181527
Intermediate Similarity 0.7089 NPC314098
Intermediate Similarity 0.7088 NPC471742
Intermediate Similarity 0.707 NPC122235
Intermediate Similarity 0.7052 NPC27904
Intermediate Similarity 0.7037 NPC159722
Remote Similarity 0.6944 NPC471743
Remote Similarity 0.6905 NPC259678
Remote Similarity 0.6903 NPC268534
Remote Similarity 0.6898 NPC313293
Remote Similarity 0.6883 NPC150323
Remote Similarity 0.6882 NPC144691
Remote Similarity 0.6875 NPC189116
Remote Similarity 0.6816 NPC471778
Remote Similarity 0.6813 NPC219848
Remote Similarity 0.678 NPC204867
Remote Similarity 0.6776 NPC256268
Remote Similarity 0.6774 NPC279385
Remote Similarity 0.6774 NPC179605
Remote Similarity 0.6772 NPC205946
Remote Similarity 0.6757 NPC243058
Remote Similarity 0.6731 NPC103292
Remote Similarity 0.672 NPC203635
Remote Similarity 0.6717 NPC477999
Remote Similarity 0.6711 NPC216122
Remote Similarity 0.6649 NPC90415
Remote Similarity 0.6648 NPC471130
Remote Similarity 0.6646 NPC209389
Remote Similarity 0.6629 NPC88970
Remote Similarity 0.6629 NPC199737
Remote Similarity 0.6605 NPC477432
Remote Similarity 0.6588 NPC130797
Remote Similarity 0.6584 NPC72473
Remote Similarity 0.6584 NPC307437
Remote Similarity 0.6584 NPC58827
Remote Similarity 0.6568 NPC472241
Remote Similarity 0.6559 NPC475685
Remote Similarity 0.6527 NPC43218
Remote Similarity 0.6519 NPC257490
Remote Similarity 0.6508 NPC316141
Remote Similarity 0.648 NPC322644
Remote Similarity 0.6478 NPC39818
Remote Similarity 0.6453 NPC472242
Remote Similarity 0.645 NPC472243
Remote Similarity 0.644 NPC278434
Remote Similarity 0.6438 NPC254698
Remote Similarity 0.6432 NPC475594
Remote Similarity 0.6429 NPC316574
Remote Similarity 0.6413 NPC112336
Remote Similarity 0.6413 NPC474814
Remote Similarity 0.6398 NPC475607
Remote Similarity 0.6398 NPC192533
Remote Similarity 0.6392 NPC291962
Remote Similarity 0.6392 NPC177684
Remote Similarity 0.6383 NPC298320
Remote Similarity 0.6376 NPC324786
Remote Similarity 0.6364 NPC314223
Remote Similarity 0.6364 NPC474081
Remote Similarity 0.6358 NPC470343
Remote Similarity 0.6358 NPC172170
Remote Similarity 0.6358 NPC472244
Remote Similarity 0.6354 NPC473815
Remote Similarity 0.6353 NPC314252
Remote Similarity 0.6353 NPC181526
Remote Similarity 0.6352 NPC161956
Remote Similarity 0.6352 NPC112373
Remote Similarity 0.6352 NPC258531
Remote Similarity 0.6344 NPC470548
Remote Similarity 0.6324 NPC318183
Remote Similarity 0.6321 NPC477998
Remote Similarity 0.6319 NPC314278
Remote Similarity 0.6307 NPC241392
Remote Similarity 0.6304 NPC470971
Remote Similarity 0.6301 NPC323798
Remote Similarity 0.63 NPC471944
Remote Similarity 0.6298 NPC93653
Remote Similarity 0.6294 NPC319645
Remote Similarity 0.629 NPC177261
Remote Similarity 0.6244 NPC21483
Remote Similarity 0.6244 NPC198205
Remote Similarity 0.6243 NPC36495
Remote Similarity 0.6243 NPC474815
Remote Similarity 0.6243 NPC474041
Remote Similarity 0.6243 NPC475761
Remote Similarity 0.6237 NPC126676
Remote Similarity 0.6237 NPC469671
Remote Similarity 0.6235 NPC287358
Remote Similarity 0.6231 NPC311054
Remote Similarity 0.6231 NPC112752
Remote Similarity 0.6229 NPC146370
Remote Similarity 0.6228 NPC476687
Remote Similarity 0.6228 NPC476689
Remote Similarity 0.6228 NPC476685
Remote Similarity 0.6221 NPC2823
Remote Similarity 0.6215 NPC13526
Remote Similarity 0.6211 NPC283810
Remote Similarity 0.62 NPC107828
Remote Similarity 0.62 NPC291426
Remote Similarity 0.62 NPC90358
Remote Similarity 0.6199 NPC315224
Remote Similarity 0.6196 NPC299582
Remote Similarity 0.6185 NPC301702
Remote Similarity 0.6181 NPC198390
Remote Similarity 0.6173 NPC138370
Remote Similarity 0.617 NPC303225
Remote Similarity 0.6168 NPC316746
Remote Similarity 0.6166 NPC49184
Remote Similarity 0.6154 NPC316104
Remote Similarity 0.6154 NPC162417
Remote Similarity 0.615 NPC292265
Remote Similarity 0.6146 NPC471785
Remote Similarity 0.6139 NPC136573
Remote Similarity 0.6139 NPC176371
Remote Similarity 0.6134 NPC160381
Remote Similarity 0.6127 NPC316202
Remote Similarity 0.6127 NPC314648
Remote Similarity 0.6121 NPC322433
Remote Similarity 0.6121 NPC250476
Remote Similarity 0.6108 NPC472245
Remote Similarity 0.6108 NPC288759
Remote Similarity 0.6105 NPC9475
Remote Similarity 0.61 NPC141454
Remote Similarity 0.6096 NPC472118
Remote Similarity 0.6087 NPC257763
Remote Similarity 0.6071 NPC231382
Remote Similarity 0.6071 NPC221873
Remote Similarity 0.607 NPC474916
Remote Similarity 0.6061 NPC114039
Remote Similarity 0.6061 NPC206109
Remote Similarity 0.6057 NPC308197
Remote Similarity 0.6051 NPC150308
Remote Similarity 0.6051 NPC194040
Remote Similarity 0.6049 NPC301292
Remote Similarity 0.6049 NPC313112
Remote Similarity 0.6041 NPC83111
Remote Similarity 0.6039 NPC37584
Remote Similarity 0.6034 NPC471164
Remote Similarity 0.6029 NPC475223
Remote Similarity 0.6027 NPC472844
Remote Similarity 0.6023 NPC300299
Remote Similarity 0.602 NPC206186
Remote Similarity 0.6019 NPC313796
Remote Similarity 0.6019 NPC313345
Remote Similarity 0.6019 NPC315638
Remote Similarity 0.6019 NPC314855
Remote Similarity 0.6011 NPC315829
Remote Similarity 0.601 NPC92803
Remote Similarity 0.6 NPC475983
Remote Similarity 0.6 NPC246983
Remote Similarity 0.6 NPC202812
Remote Similarity 0.6 NPC165599
Remote Similarity 0.6 NPC282103
Remote Similarity 0.6 NPC475448
Remote Similarity 0.599 NPC18890
Remote Similarity 0.599 NPC315545
Remote Similarity 0.599 NPC314297
Remote Similarity 0.5989 NPC41717
Remote Similarity 0.5988 NPC226143
Remote Similarity 0.5977 NPC315051
Remote Similarity 0.5969 NPC84347
Remote Similarity 0.5966 NPC314287
Remote Similarity 0.5965 NPC184437
Remote Similarity 0.5962 NPC39679
Remote Similarity 0.5959 NPC85613
Remote Similarity 0.5955 NPC470579
Remote Similarity 0.5955 NPC478039
Remote Similarity 0.5954 NPC316906
Remote Similarity 0.5952 NPC150863
Remote Similarity 0.5952 NPC204303
Remote Similarity 0.5947 NPC73280
Remote Similarity 0.5942 NPC225400
Remote Similarity 0.5941 NPC90229
Remote Similarity 0.5932 NPC136002
Remote Similarity 0.593 NPC203628
Remote Similarity 0.5928 NPC472163
Remote Similarity 0.5924 NPC61013
Remote Similarity 0.5924 NPC313981
Remote Similarity 0.5924 NPC244856
Remote Similarity 0.5924 NPC123241
Remote Similarity 0.592 NPC476129
Remote Similarity 0.592 NPC476212
Remote Similarity 0.592 NPC476205
Remote Similarity 0.592 NPC476207
Remote Similarity 0.592 NPC476257
Remote Similarity 0.592 NPC476256
Remote Similarity 0.592 NPC83214
Remote Similarity 0.592 NPC476206
Remote Similarity 0.592 NPC259791

Drug Structure

External Identifiers

TTD   DAP000815; DNC000919
DrugBank   DB00939
ChEMBL   CHEMBL509
IUPHAR/BPS   7219
PharmaGKB   PA450341
KEGG Drug   D02341
PubChem CID   4037
ChEBI   6710
CAS Number  644-62-2

Drug Properties

Molecular Weight  295.02
ALogP  1.4704
MLogP  2.45
XLogP  4.669
HDA  3
HBD  2
Rotatable Bonds  7
TPSA  49.33
RO5 Violation  0