Natural Product: NPC264782

Natural Product ID:  NPC264782
Common Name:   N-(4-Methoxyphenyl)Acetamide
IUPAC Name:   N-(4-methoxyphenyl)acetamide
Synonyms:  
Molecular Formula:   C9H11NO2
Standard InCHIKey:  XVAIDCNLVLTVFM-UHFFFAOYSA-N
Standard InCHI:  InChI=1S/C9H11NO2/c1-7(11)10-8-3-5-9(12-2)6-4-8/h3-6H,1-2H3,(H,10,11)
Canonical SMILES:  COc1ccc(cc1)N=C(O)C
First Find Year:  
Max Developmental Stage:  
Synthetic Gene Cluster:   ;

  Species Source

Organism ID Organism Name Taxonomy Level Family SuperKingdom Isolation Part Collection Location Collection Time Reference
NPO24248.1 Lactarius deliciosus var. deterrimus Varieties Russulaceae Eukaryota UNPD*
NPO1117 Hypholoma capnoides Species Strophariaceae Eukaryota UNPD*
NPO9366 Rosa transmorrisonensis Species Rosaceae Eukaryota UNPD*
NPO2629 Cystoseira caespitosa Species Sargassaceae Eukaryota UNPD*

  Biological Activity

Target ID Target Type Target Name Target Organism Activity Type Activity Relation Value Unit Reference
NPT2 Others Unspecified Potency 39553.5 nM PubChem BioAssay data set
NPT2 Others Unspecified Potency 50239 nM PubChem BioAssay data set
NPT2 Others Unspecified Potency 31698.7 nM PubChem BioAssay data set
NPT2 Others Unspecified Potency 28001.7 nM PubChem BioAssay data set

  Similar Natural Products in NPASS

Similarity level is defined by Tanimoto coefficient (Tc) between two molecules. Tc lies between [0, 1] where '1' indicates the highest similarity. What is Tanimoto coefficient

●  The left chart: Distribution of similarity level between NPC264782 and all remaining natural products in the NPASS database.
●  The right table: Most similar natural products (Tc>=0.56 or Top200).

Similarity Score Similarity Level Natural Product ID
0.8889 High Similarity NPC76327
0.8264 Intermediate Similarity NPC315632
0.823 Intermediate Similarity NPC255721
0.8158 Intermediate Similarity NPC226914
0.8158 Intermediate Similarity NPC9336
0.7874 Intermediate Similarity NPC473987
0.7838 Intermediate Similarity NPC70201
0.7829 Intermediate Similarity NPC297584
0.7721 Intermediate Similarity NPC473769
0.7674 Intermediate Similarity NPC313466
0.7586 Intermediate Similarity NPC44836
0.75 Intermediate Similarity NPC53596
0.75 Intermediate Similarity NPC322735
0.75 Intermediate Similarity NPC160120
0.75 Intermediate Similarity NPC17388
0.75 Intermediate Similarity NPC289330
0.75 Intermediate Similarity NPC471308
0.7481 Intermediate Similarity NPC208022
0.7438 Intermediate Similarity NPC329190
0.7323 Intermediate Similarity NPC471315
0.7323 Intermediate Similarity NPC471314
0.7319 Intermediate Similarity NPC260601
0.7292 Intermediate Similarity NPC112766
0.725 Intermediate Similarity NPC329358
0.7241 Intermediate Similarity NPC311660
0.7236 Intermediate Similarity NPC222982
0.7227 Intermediate Similarity NPC146530
0.7226 Intermediate Similarity NPC314113
0.7179 Intermediate Similarity NPC256838
0.7177 Intermediate Similarity NPC258992
0.7174 Intermediate Similarity NPC476462
0.7143 Intermediate Similarity NPC19023
0.7143 Intermediate Similarity NPC307456
0.7143 Intermediate Similarity NPC473874
0.7123 Intermediate Similarity NPC70549
0.712 Intermediate Similarity NPC323948
0.7097 Intermediate Similarity NPC303370
0.7083 Intermediate Similarity NPC219383
0.7055 Intermediate Similarity NPC10875
0.7055 Intermediate Similarity NPC10730
0.7049 Intermediate Similarity NPC166837
0.7048 Intermediate Similarity NPC124576
0.7037 Intermediate Similarity NPC23837
0.7027 Intermediate Similarity NPC306366
0.7009 Intermediate Similarity NPC15839
0.6953 Remote Similarity NPC41801
0.6953 Remote Similarity NPC263835
0.6937 Remote Similarity NPC157213
0.6917 Remote Similarity NPC41594
0.6913 Remote Similarity NPC231862
0.6889 Remote Similarity NPC255550
0.6889 Remote Similarity NPC308885
0.6875 Remote Similarity NPC43275
0.6875 Remote Similarity NPC256369
0.6875 Remote Similarity NPC321869
0.6847 Remote Similarity NPC206876
0.6842 Remote Similarity NPC476483
0.6838 Remote Similarity NPC93882
0.6838 Remote Similarity NPC130595
0.6824 Remote Similarity NPC315257
0.6818 Remote Similarity NPC325013
0.6814 Remote Similarity NPC318429
0.68 Remote Similarity NPC235628
0.68 Remote Similarity NPC285635
0.6788 Remote Similarity NPC6854
0.6788 Remote Similarity NPC91615
0.6788 Remote Similarity NPC285078
0.6788 Remote Similarity NPC313737
0.6776 Remote Similarity NPC70172
0.6776 Remote Similarity NPC204179
0.6761 Remote Similarity NPC168750
0.6755 Remote Similarity NPC315498
0.6755 Remote Similarity NPC230942
0.6755 Remote Similarity NPC57105
0.6752 Remote Similarity NPC313918
0.6742 Remote Similarity NPC211218
0.6741 Remote Similarity NPC471306
0.6741 Remote Similarity NPC471321
0.6739 Remote Similarity NPC218530
0.6732 Remote Similarity NPC314861
0.6726 Remote Similarity NPC302546
0.6721 Remote Similarity NPC186469
0.6713 Remote Similarity NPC323798
0.6694 Remote Similarity NPC42383
0.6692 Remote Similarity NPC95733
0.6692 Remote Similarity NPC62101
0.6689 Remote Similarity NPC26872
0.6667 Remote Similarity NPC309982
0.6667 Remote Similarity NPC178902
0.6667 Remote Similarity NPC97811
0.6645 Remote Similarity NPC177404
0.6643 Remote Similarity NPC166667
0.6641 Remote Similarity NPC83279
0.6638 Remote Similarity NPC16649
0.6638 Remote Similarity NPC114325
0.6637 Remote Similarity NPC47422
0.6603 Remote Similarity NPC310894
0.6603 Remote Similarity NPC258773
0.6596 Remote Similarity NPC476475
0.6596 Remote Similarity NPC471316
0.6593 Remote Similarity NPC301713
0.6579 Remote Similarity NPC259134
0.6579 Remote Similarity NPC177844
0.6579 Remote Similarity NPC99886
0.6579 Remote Similarity NPC8002
0.6579 Remote Similarity NPC78154
0.6577 Remote Similarity NPC125306
0.6556 Remote Similarity NPC26850
0.6555 Remote Similarity NPC100870
0.6544 Remote Similarity NPC153990
0.6544 Remote Similarity NPC251571
0.6538 Remote Similarity NPC477888
0.6529 Remote Similarity NPC178681
0.6522 Remote Similarity NPC71853
0.6519 Remote Similarity NPC29477
0.6508 Remote Similarity NPC21890
0.6504 Remote Similarity NPC231705
0.6497 Remote Similarity NPC85482
0.6496 Remote Similarity NPC155838
0.6478 Remote Similarity NPC168153
0.6475 Remote Similarity NPC274732
0.6475 Remote Similarity NPC471953
0.6475 Remote Similarity NPC470392
0.6471 Remote Similarity NPC93653
0.6466 Remote Similarity NPC321956
0.6454 Remote Similarity NPC122542
0.6452 Remote Similarity NPC142297
0.6449 Remote Similarity NPC52029
0.6449 Remote Similarity NPC35961
0.6449 Remote Similarity NPC195749
0.6446 Remote Similarity NPC51633
0.6439 Remote Similarity NPC321133
0.6434 Remote Similarity NPC204156
0.6417 Remote Similarity NPC132725
0.6417 Remote Similarity NPC314803
0.6417 Remote Similarity NPC307039
0.6408 Remote Similarity NPC126637
0.6406 Remote Similarity NPC26524
0.6403 Remote Similarity NPC114102
0.64 Remote Similarity NPC184161
0.6397 Remote Similarity NPC250476
0.6393 Remote Similarity NPC192596
0.6393 Remote Similarity NPC305205
0.6392 Remote Similarity NPC14651
0.6392 Remote Similarity NPC121658
0.6389 Remote Similarity NPC83289
0.6389 Remote Similarity NPC212850
0.6389 Remote Similarity NPC189724
0.6387 Remote Similarity NPC118511
0.638 Remote Similarity NPC469831
0.6377 Remote Similarity NPC469977
0.637 Remote Similarity NPC470404
0.637 Remote Similarity NPC470403
0.637 Remote Similarity NPC217277
0.637 Remote Similarity NPC470394
0.6364 Remote Similarity NPC469828
0.6357 Remote Similarity NPC214869
0.6356 Remote Similarity NPC471581
0.635 Remote Similarity NPC251466
0.6349 Remote Similarity NPC258056
0.6341 Remote Similarity NPC2518
0.6341 Remote Similarity NPC38079
0.6341 Remote Similarity NPC12987
0.6341 Remote Similarity NPC474603
0.6341 Remote Similarity NPC108875
0.6335 Remote Similarity NPC315631
0.6333 Remote Similarity NPC175298
0.6333 Remote Similarity NPC40209
0.6331 Remote Similarity NPC470706
0.6329 Remote Similarity NPC476518
0.6325 Remote Similarity NPC66083
0.6324 Remote Similarity NPC300955
0.6323 Remote Similarity NPC72291
0.632 Remote Similarity NPC37584
0.6319 Remote Similarity NPC47986
0.6312 Remote Similarity NPC169766
0.6304 Remote Similarity NPC172403
0.6304 Remote Similarity NPC186898
0.6304 Remote Similarity NPC259098
0.6304 Remote Similarity NPC197680
0.6299 Remote Similarity NPC474149
0.6299 Remote Similarity NPC95977
0.6296 Remote Similarity NPC316161
0.6293 Remote Similarity NPC92689
0.629 Remote Similarity NPC17537
0.629 Remote Similarity NPC288760
0.629 Remote Similarity NPC307875
0.629 Remote Similarity NPC470393
0.629 Remote Similarity NPC227255
0.6284 Remote Similarity NPC470395
0.6277 Remote Similarity NPC246133
0.6277 Remote Similarity NPC182147
0.6277 Remote Similarity NPC152186
0.6277 Remote Similarity NPC170583
0.6277 Remote Similarity NPC71105
0.6277 Remote Similarity NPC207541
0.6273 Remote Similarity NPC290069
0.627 Remote Similarity NPC24101
0.627 Remote Similarity NPC96224
0.6266 Remote Similarity NPC1527

  Similar Clinical/Approved Drugs

Similarity level is defined by Tanimoto coefficient (Tc) between two molecules.

●  The left chart: Distribution of similarity level between NPC264782 and all drugs/candidates.
●  The right table: Most similar clinical/approved drugs (Tc>=0.56 or Top200).

Similarity Score Similarity Level Drug ID Developmental Stage
0.9633 High Similarity NPD254 Approved
0.8889 High Similarity NPD9507 Approved
0.84 Intermediate Similarity NPD756 Suspended
0.8254 Intermediate Similarity NPD1393 Approved
0.8077 Intermediate Similarity NPD1422 Approved
0.7879 Intermediate Similarity NPD7083 Clinical (unspecified phase)
0.7845 Intermediate Similarity NPD9376 Approved
0.7823 Intermediate Similarity NPD1158 Phase 2
0.7815 Intermediate Similarity NPD9342 Approved
0.7727 Intermediate Similarity NPD204 Clinical (unspecified phase)
0.7638 Intermediate Similarity NPD1160 Phase 2
0.7594 Intermediate Similarity NPD822 Approved
0.7594 Intermediate Similarity NPD5788 Clinical (unspecified phase)
0.7462 Intermediate Similarity NPD1314 Clinical (unspecified phase)
0.746 Intermediate Similarity NPD522 Approved
0.7447 Intermediate Similarity NPD950 Clinical (unspecified phase)
0.7438 Intermediate Similarity NPD286 Approved
0.7364 Intermediate Similarity NPD848 Approved
0.7364 Intermediate Similarity NPD849 Approved
0.7364 Intermediate Similarity NPD850 Approved
0.7319 Intermediate Similarity NPD2241 Approved
0.7226 Intermediate Similarity NPD521 Clinical (unspecified phase)
0.7222 Intermediate Similarity NPD3296 Phase 1
0.7174 Intermediate Similarity NPD5719 Approved
0.7172 Intermediate Similarity NPD2366 Approved
0.7163 Intermediate Similarity NPD2752 Clinical (unspecified phase)
0.7163 Intermediate Similarity NPD2114 Discontinued
0.7092 Intermediate Similarity NPD1305 Clinical (unspecified phase)
0.7055 Intermediate Similarity NPD4255 Phase 1
0.7049 Intermediate Similarity NPD308 Approved
0.6984 Remote Similarity NPD313 Approved
0.697 Remote Similarity NPD9723 Approved
0.6966 Remote Similarity NPD1678 Clinical (unspecified phase)
0.6966 Remote Similarity NPD4003 Phase 3
0.6954 Remote Similarity NPD4943 Phase 2
0.6954 Remote Similarity NPD4944 Phase 2
0.6939 Remote Similarity NPD980 Clinical (unspecified phase)
0.6937 Remote Similarity NPD9295 Approved
0.6918 Remote Similarity NPD5811 Approved
0.6889 Remote Similarity NPD3145 Approved
0.6889 Remote Similarity NPD3144 Approved
0.687 Remote Similarity NPD3676 Clinical (unspecified phase)
0.6861 Remote Similarity NPD9694 Discovery
0.6846 Remote Similarity NPD6060 Clinical (unspecified phase)
0.6842 Remote Similarity NPD1394 Approved
0.6838 Remote Similarity NPD7477 Discontinued
0.6838 Remote Similarity NPD2674 Phase 3
0.6824 Remote Similarity NPD1440 Discontinued
0.6824 Remote Similarity NPD3236 Phase 3
0.6824 Remote Similarity NPD3237 Clinical (unspecified phase)
0.6821 Remote Similarity NPD3453 Discontinued
0.6814 Remote Similarity NPD9365 Approved
0.6809 Remote Similarity NPD4597 Approved
0.6809 Remote Similarity NPD4598 Approved
0.6781 Remote Similarity NPD3627 Approved
0.6779 Remote Similarity NPD3812 Clinical (unspecified phase)
0.6757 Remote Similarity NPD1557 Discontinued
0.6757 Remote Similarity NPD5617 Suspended
0.6755 Remote Similarity NPD19 Approved
0.6755 Remote Similarity NPD1742 Approved
0.6755 Remote Similarity NPD1191 Discontinued
0.6755 Remote Similarity NPD1743 Approved
0.6742 Remote Similarity NPD1669 Approved
0.6738 Remote Similarity NPD7752 Approved
0.6738 Remote Similarity NPD7753 Approved
0.672 Remote Similarity NPD821 Approved
0.6691 Remote Similarity NPD1024 Discontinued
0.6689 Remote Similarity NPD3559 Clinical (unspecified phase)
0.6689 Remote Similarity NPD3560 Approved
0.6689 Remote Similarity NPD3558 Approved
0.6689 Remote Similarity NPD3557 Approved
0.6689 Remote Similarity NPD3556 Approved
0.6688 Remote Similarity NPD4986 Clinical (unspecified phase)
0.6688 Remote Similarity NPD6379 Discontinued
0.6667 Remote Similarity NPD4796 Discontinued
0.6667 Remote Similarity NPD9469 Approved
0.6667 Remote Similarity NPD8330 Clinical (unspecified phase)
0.6638 Remote Similarity NPD9296 Approved
0.6623 Remote Similarity NPD1850 Phase 3
0.6623 Remote Similarity NPD2341 Discontinued
0.6622 Remote Similarity NPD2883 Discontinued
0.6614 Remote Similarity NPD593 Approved
0.6614 Remote Similarity NPD595 Approved
0.6603 Remote Similarity NPD4083 Discontinued
0.66 Remote Similarity NPD3778 Approved
0.6585 Remote Similarity NPD5374 Approved
0.6585 Remote Similarity NPD5373 Approved
0.6581 Remote Similarity NPD3984 Clinical (unspecified phase)
0.6581 Remote Similarity NPD3983 Phase 3
0.6581 Remote Similarity NPD2821 Approved
0.6579 Remote Similarity NPD6063 Approved
0.6558 Remote Similarity NPD2190 Approved
0.6544 Remote Similarity NPD4993 Discontinued
0.6538 Remote Similarity NPD4606 Clinical (unspecified phase)
0.6528 Remote Similarity NPD965 Approved
0.6525 Remote Similarity NPD6636 Phase 3
0.6525 Remote Similarity NPD696 Discontinued
0.6513 Remote Similarity NPD6738 Phase 2
0.6513 Remote Similarity NPD6737 Phase 2
0.6507 Remote Similarity NPD1084 Clinical (unspecified phase)
0.6503 Remote Similarity NPD3656 Approved
0.65 Remote Similarity NPD654 Phase 3
0.6497 Remote Similarity NPD2215 Approved
0.6497 Remote Similarity NPD2216 Approved
0.6493 Remote Similarity NPD1421 Approved
0.6493 Remote Similarity NPD1420 Approved
0.6489 Remote Similarity NPD2595 Approved
0.6489 Remote Similarity NPD2594 Approved
0.648 Remote Similarity NPD556 Approved
0.6479 Remote Similarity NPD3693 Clinical (unspecified phase)
0.6475 Remote Similarity NPD839 Approved
0.6475 Remote Similarity NPD840 Approved
0.646 Remote Similarity NPD6184 Discontinued
0.6458 Remote Similarity NPD7153 Discontinued
0.6454 Remote Similarity NPD442 Discontinued
0.6454 Remote Similarity NPD1772 Clinical (unspecified phase)
0.6447 Remote Similarity NPD1861 Discovery
0.6446 Remote Similarity NPD291 Approved
0.6439 Remote Similarity NPD2668 Approved
0.6439 Remote Similarity NPD2667 Approved
0.6438 Remote Similarity NPD3301 Approved
0.6434 Remote Similarity NPD3391 Approved
0.6423 Remote Similarity NPD1712 Approved
0.6415 Remote Similarity NPD5602 Clinical (unspecified phase)
0.6392 Remote Similarity NPD5680 Clinical (unspecified phase)
0.6389 Remote Similarity NPD9245 Clinical (unspecified phase)
0.6387 Remote Similarity NPD6533 Clinical (unspecified phase)
0.638 Remote Similarity NPD2802 Phase 3
0.637 Remote Similarity NPD4129 Approved
0.6369 Remote Similarity NPD6872 Clinical (unspecified phase)
0.6364 Remote Similarity NPD190 Phase 1
0.6364 Remote Similarity NPD3153 Approved
0.6364 Remote Similarity NPD2358 Clinical (unspecified phase)
0.6364 Remote Similarity NPD3154 Approved
0.6356 Remote Similarity NPD665 Phase 2
0.6352 Remote Similarity NPD6607 Clinical (unspecified phase)
0.6352 Remote Similarity NPD677 Clinical (unspecified phase)
0.6352 Remote Similarity NPD5078 Clinical (unspecified phase)
0.6335 Remote Similarity NPD5334 Clinical (unspecified phase)
0.6335 Remote Similarity NPD3965 Phase 1
0.6328 Remote Similarity NPD181 Approved
0.632 Remote Similarity NPD9624 Approved
0.6319 Remote Similarity NPD3156 Discontinued
0.6319 Remote Similarity NPD7149 Clinical (unspecified phase)
0.6308 Remote Similarity NPD709 Approved
0.6306 Remote Similarity NPD1414 Approved
0.6306 Remote Similarity NPD1411 Approved
0.6306 Remote Similarity NPD1413 Approved
0.6304 Remote Similarity NPD2250 Discontinued
0.6303 Remote Similarity NPD6045 Phase 3
0.6301 Remote Similarity NPD2458 Approved
0.6301 Remote Similarity NPD2459 Approved
0.6301 Remote Similarity NPD2460 Phase 3
0.6299 Remote Similarity NPD2673 Approved
0.6299 Remote Similarity NPD2671 Approved
0.6291 Remote Similarity NPD814 Clinical (unspecified phase)
0.6291 Remote Similarity NPD3564 Approved
0.6291 Remote Similarity NPD3563 Approved
0.6291 Remote Similarity NPD3562 Approved
0.6291 Remote Similarity NPD493 Approved
0.6291 Remote Similarity NPD5267 Discontinued
0.6277 Remote Similarity NPD3568 Approved
0.6277 Remote Similarity NPD3567 Approved
0.6275 Remote Similarity NPD2672 Discontinued
0.6275 Remote Similarity NPD4201 Clinical (unspecified phase)
0.6275 Remote Similarity NPD4205 Phase 3
0.6267 Remote Similarity NPD9509 Clinical (unspecified phase)
0.6266 Remote Similarity NPD3511 Discontinued
0.625 Remote Similarity NPD1169 Approved
0.625 Remote Similarity NPD4081 Clinical (unspecified phase)
0.625 Remote Similarity NPD3952 Approved
0.625 Remote Similarity NPD6357 Discontinued
0.625 Remote Similarity NPD3953 Clinical (unspecified phase)
0.625 Remote Similarity NPD3951 Phase 3
0.625 Remote Similarity NPD789 Phase 2
0.6241 Remote Similarity NPD1797 Approved
0.6241 Remote Similarity NPD1798 Approved
0.6235 Remote Similarity NPD5670 Approved
0.6232 Remote Similarity NPD2990 Approved
0.6232 Remote Similarity NPD2987 Approved
0.622 Remote Similarity NPD3037 Phase 1
0.6211 Remote Similarity NPD5966 Clinical (unspecified phase)
0.621 Remote Similarity NPD9501 Approved
0.6209 Remote Similarity NPD3538 Suspended
0.6207 Remote Similarity NPD2161 Phase 2
0.62 Remote Similarity NPD681 Clinical (unspecified phase)
0.6194 Remote Similarity NPD5294 Clinical (unspecified phase)
0.619 Remote Similarity NPD6364 Approved
0.619 Remote Similarity NPD290 Approved
0.619 Remote Similarity NPD44 Approved
0.6187 Remote Similarity NPD5266 Clinical (unspecified phase)
0.6187 Remote Similarity NPD2040 Clinical (unspecified phase)
0.6176 Remote Similarity NPD4325 Phase 2
0.6176 Remote Similarity NPD2230 Approved
0.6176 Remote Similarity NPD4324 Phase 2
0.6176 Remote Similarity NPD2233 Approved
0.6176 Remote Similarity NPD2232 Approved
0.6173 Remote Similarity NPD4020 Clinical (unspecified phase)
0.6168 Remote Similarity NPD9542 Approved
0.6165 Remote Similarity NPD2486 Discontinued

Structure

External Identifiers

PubChem CID   5827
ChEMBL   CHEMBL3183230
ZINC  

Physicochemical Properties

Molecular Weight:  165.08
ALogP:  -0.1235
MLogP:  2.12
XLogP:  2.185
# Rotatable Bonds:  5
Polar Surface Area:  41.82
# H-Bond Aceptor:  2
# H-Bond Donor:  1
# Rings:  1
# Heavy Atoms:  12

Download Data

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General Info & Identifiers & Properties  
Structure MOL file  
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Biological Activities  
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