Natural Product: NPC172066

Natural Product ID:  NPC172066
Common Name:   (E)-3-[(1R,4S,7R,7Ar)-1-Hydroxy-3,7-Dimethyl-2,4,5,6,7,7A-Hexahydro-1H-Inden-4-Yl]-2-Methylprop-2-Enoic Acid
IUPAC Name:   (E)-3-[(1R,4S,7R,7aR)-1-hydroxy-3,7-dimethyl-2,4,5,6,7,7a-hexahydro-1H-inden-4-yl]-2-methylprop-2-enoic acid
Synonyms:  
Molecular Formula:   C15H22O3
Standard InCHIKey:  XJNQXTISSHEQKD-UNXUOHHUSA-N
Standard InCHI:  InChI=1S/C15H22O3/c1-8-4-5-11(6-10(3)15(17)18)13-9(2)7-12(16)14(8)13/h6,8,11-12,14,16H,4-5,7H2,1-3H3,(H,17,18)/b10-6+/t8-,11+,12-,14+/m1/s1
Canonical SMILES:  C[C@@H]1CC[C@H](C2=C(C[C@H]([C@H]12)O)C)/C=C(/C(=O)O)C
First Find Year:  
Max Developmental Stage:  
Synthetic Gene Cluster:   ;

  Species Source

Organism ID Organism Name Taxonomy Level Family SuperKingdom Isolation Part Collection Location Collection Time Reference
NPO17333 Valeriana officinalis Species Caprifoliaceae Eukaryota TCMID*

  Biological Activity

Target ID Target Type Target Name Target Organism Activity Type Activity Relation Value Unit Reference
NPT94 Individual Protein Aldehyde dehydrogenase 1A1 Homo sapiens Potency = 39810.7 nM PubChem BioAssay data set
NPT249 Individual Protein Glucocorticoid receptor Homo sapiens Potency 4 nM PubChem BioAssay data set
NPT153 Individual Protein Androgen Receptor Homo sapiens Potency 2.2 nM PubChem BioAssay data set
NPT540 Individual Protein Bile acid receptor FXR Homo sapiens Potency 35481.3 nM PubChem BioAssay data set
NPT162 Individual Protein Heat shock protein beta-1 Homo sapiens Potency 61049.5 nM PubChem BioAssay data set
NPT2 Others Unspecified Potency 61049.5 nM PubChem BioAssay data set
NPT2 Others Unspecified Potency 76176.9 nM PubChem BioAssay data set
NPT2 Others Unspecified Potency 1085.6 nM PubChem BioAssay data set
NPT2 Others Unspecified Potency 60509.4 nM PubChem BioAssay data set

  Similar Natural Products in NPASS

Similarity level is defined by Tanimoto coefficient (Tc) between two molecules. Tc lies between [0, 1] where '1' indicates the highest similarity. What is Tanimoto coefficient

●  The left chart: Distribution of similarity level between NPC172066 and all remaining natural products in the NPASS database.
●  The right table: Most similar natural products (Tc>=0.56 or Top200).

Similarity Score Similarity Level Natural Product ID
0.8472 Intermediate Similarity NPC81907
0.825 Intermediate Similarity NPC271104
0.8235 Intermediate Similarity NPC146554
0.8171 Intermediate Similarity NPC57370
0.8072 Intermediate Similarity NPC302360
0.8049 Intermediate Similarity NPC224455
0.8023 Intermediate Similarity NPC472240
0.8023 Intermediate Similarity NPC262858
0.7927 Intermediate Similarity NPC159148
0.7907 Intermediate Similarity NPC249889
0.7907 Intermediate Similarity NPC193843
0.7865 Intermediate Similarity NPC476186
0.7841 Intermediate Similarity NPC74296
0.7841 Intermediate Similarity NPC110923
0.7841 Intermediate Similarity NPC212948
0.7816 Intermediate Similarity NPC474396
0.7816 Intermediate Similarity NPC314727
0.7816 Intermediate Similarity NPC310236
0.7816 Intermediate Similarity NPC50488
0.7805 Intermediate Similarity NPC281880
0.7791 Intermediate Similarity NPC312561
0.7778 Intermediate Similarity NPC475994
0.7778 Intermediate Similarity NPC192006
0.7765 Intermediate Similarity NPC109528
0.7765 Intermediate Similarity NPC471795
0.7753 Intermediate Similarity NPC214697
0.7753 Intermediate Similarity NPC476304
0.7738 Intermediate Similarity NPC472377
0.7738 Intermediate Similarity NPC79945
0.7738 Intermediate Similarity NPC311070
0.7738 Intermediate Similarity NPC215893
0.7738 Intermediate Similarity NPC42476
0.7733 Intermediate Similarity NPC202017
0.7727 Intermediate Similarity NPC182136
0.7717 Intermediate Similarity NPC197386
0.7717 Intermediate Similarity NPC166745
0.7717 Intermediate Similarity NPC218107
0.7717 Intermediate Similarity NPC235464
0.7711 Intermediate Similarity NPC6663
0.7701 Intermediate Similarity NPC7280
0.7701 Intermediate Similarity NPC229612
0.7701 Intermediate Similarity NPC472870
0.7692 Intermediate Similarity NPC190713
0.7692 Intermediate Similarity NPC319163
0.7692 Intermediate Similarity NPC67076
0.7674 Intermediate Similarity NPC472869
0.7674 Intermediate Similarity NPC476043
0.7674 Intermediate Similarity NPC194417
0.7667 Intermediate Similarity NPC119562
0.7667 Intermediate Similarity NPC279410
0.7647 Intermediate Similarity NPC472326
0.7647 Intermediate Similarity NPC248758
0.7647 Intermediate Similarity NPC19849
0.7647 Intermediate Similarity NPC472865
0.7647 Intermediate Similarity NPC165064
0.7647 Intermediate Similarity NPC472864
0.764 Intermediate Similarity NPC473675
0.7619 Intermediate Similarity NPC2524
0.7609 Intermediate Similarity NPC141401
0.7595 Intermediate Similarity NPC35656
0.7582 Intermediate Similarity NPC476174
0.7564 Intermediate Similarity NPC318766
0.7558 Intermediate Similarity NPC474853
0.7558 Intermediate Similarity NPC179006
0.7556 Intermediate Similarity NPC115021
0.7556 Intermediate Similarity NPC38232
0.7532 Intermediate Similarity NPC117804
0.7529 Intermediate Similarity NPC470165
0.7529 Intermediate Similarity NPC321385
0.7529 Intermediate Similarity NPC97913
0.7529 Intermediate Similarity NPC477667
0.7528 Intermediate Similarity NPC281942
0.7528 Intermediate Similarity NPC232426
0.7528 Intermediate Similarity NPC78973
0.7528 Intermediate Similarity NPC310479
0.7527 Intermediate Similarity NPC471717
0.75 Intermediate Similarity NPC456
0.75 Intermediate Similarity NPC114743
0.75 Intermediate Similarity NPC250757
0.75 Intermediate Similarity NPC6434
0.75 Intermediate Similarity NPC301534
0.75 Intermediate Similarity NPC472941
0.75 Intermediate Similarity NPC195366
0.75 Intermediate Similarity NPC104560
0.7473 Intermediate Similarity NPC53685
0.7473 Intermediate Similarity NPC57117
0.7471 Intermediate Similarity NPC82979
0.7471 Intermediate Similarity NPC175145
0.7471 Intermediate Similarity NPC475069
0.7471 Intermediate Similarity NPC473226
0.7471 Intermediate Similarity NPC329692
0.747 Intermediate Similarity NPC242767
0.747 Intermediate Similarity NPC308038
0.747 Intermediate Similarity NPC55304
0.747 Intermediate Similarity NPC226226
0.7468 Intermediate Similarity NPC29328
0.7447 Intermediate Similarity NPC470074
0.7444 Intermediate Similarity NPC141831
0.7444 Intermediate Similarity NPC472814
0.7444 Intermediate Similarity NPC72845
0.7444 Intermediate Similarity NPC177037
0.7442 Intermediate Similarity NPC472265
0.7442 Intermediate Similarity NPC164577
0.7442 Intermediate Similarity NPC33913
0.7439 Intermediate Similarity NPC315394
0.7439 Intermediate Similarity NPC203403
0.7439 Intermediate Similarity NPC97377
0.7439 Intermediate Similarity NPC132542
0.7419 Intermediate Similarity NPC99726
0.7416 Intermediate Similarity NPC5509
0.7416 Intermediate Similarity NPC168131
0.7416 Intermediate Similarity NPC214387
0.7416 Intermediate Similarity NPC477215
0.7416 Intermediate Similarity NPC476388
0.7416 Intermediate Similarity NPC470734
0.7416 Intermediate Similarity NPC232747
0.7412 Intermediate Similarity NPC256112
0.7407 Intermediate Similarity NPC476795
0.7407 Intermediate Similarity NPC474885
0.7403 Intermediate Similarity NPC114651
0.7403 Intermediate Similarity NPC477791
0.7403 Intermediate Similarity NPC472875
0.7391 Intermediate Similarity NPC173875
0.7391 Intermediate Similarity NPC183012
0.7391 Intermediate Similarity NPC318282
0.7391 Intermediate Similarity NPC469995
0.7391 Intermediate Similarity NPC174948
0.7386 Intermediate Similarity NPC237540
0.7386 Intermediate Similarity NPC471796
0.7381 Intermediate Similarity NPC138492
0.7381 Intermediate Similarity NPC472301
0.7381 Intermediate Similarity NPC233352
0.7381 Intermediate Similarity NPC45495
0.7381 Intermediate Similarity NPC824
0.7375 Intermediate Similarity NPC265485
0.7375 Intermediate Similarity NPC186042
0.7375 Intermediate Similarity NPC220939
0.7368 Intermediate Similarity NPC99411
0.7363 Intermediate Similarity NPC205034
0.7363 Intermediate Similarity NPC109305
0.7363 Intermediate Similarity NPC152778
0.7363 Intermediate Similarity NPC472871
0.7363 Intermediate Similarity NPC162615
0.7363 Intermediate Similarity NPC474736
0.7356 Intermediate Similarity NPC52628
0.7356 Intermediate Similarity NPC476426
0.7356 Intermediate Similarity NPC42586
0.7356 Intermediate Similarity NPC86316
0.7356 Intermediate Similarity NPC106416
0.7356 Intermediate Similarity NPC473251
0.7349 Intermediate Similarity NPC260814
0.7349 Intermediate Similarity NPC184737
0.7349 Intermediate Similarity NPC19443
0.7349 Intermediate Similarity NPC323249
0.7349 Intermediate Similarity NPC198240
0.7349 Intermediate Similarity NPC169095
0.7349 Intermediate Similarity NPC39547
0.7349 Intermediate Similarity NPC62336
0.7349 Intermediate Similarity NPC239098
0.7349 Intermediate Similarity NPC27949
0.7342 Intermediate Similarity NPC4299
0.7342 Intermediate Similarity NPC34834
0.734 Intermediate Similarity NPC92275
0.734 Intermediate Similarity NPC23364
0.7333 Intermediate Similarity NPC221111
0.7333 Intermediate Similarity NPC472866
0.7333 Intermediate Similarity NPC477149
0.7333 Intermediate Similarity NPC280149
0.7333 Intermediate Similarity NPC48010
0.7333 Intermediate Similarity NPC477147
0.7326 Intermediate Similarity NPC476927
0.7326 Intermediate Similarity NPC23748
0.7326 Intermediate Similarity NPC297398
0.7317 Intermediate Similarity NPC279537
0.7317 Intermediate Similarity NPC473223
0.7317 Intermediate Similarity NPC263582
0.7312 Intermediate Similarity NPC473153
0.7312 Intermediate Similarity NPC328371
0.7312 Intermediate Similarity NPC184065
0.7312 Intermediate Similarity NPC117133
0.7312 Intermediate Similarity NPC29152
0.7308 Intermediate Similarity NPC224532
0.7303 Intermediate Similarity NPC117122
0.7303 Intermediate Similarity NPC472378
0.7303 Intermediate Similarity NPC472809
0.7303 Intermediate Similarity NPC473229
0.7303 Intermediate Similarity NPC474629
0.7303 Intermediate Similarity NPC472810
0.7297 Intermediate Similarity NPC240506
0.7294 Intermediate Similarity NPC88735
0.7294 Intermediate Similarity NPC325031
0.7294 Intermediate Similarity NPC475944
0.7294 Intermediate Similarity NPC473420
0.7294 Intermediate Similarity NPC170303
0.7292 Intermediate Similarity NPC195290
0.7292 Intermediate Similarity NPC204450
0.7284 Intermediate Similarity NPC215050
0.7283 Intermediate Similarity NPC191521
0.7283 Intermediate Similarity NPC469697
0.7283 Intermediate Similarity NPC298973

  Similar Clinical/Approved Drugs

Similarity level is defined by Tanimoto coefficient (Tc) between two molecules.

●  The left chart: Distribution of similarity level between NPC172066 and all drugs/candidates.
●  The right table: Most similar clinical/approved drugs (Tc>=0.56 or Top200).

Similarity Score Similarity Level Drug ID Developmental Stage
0.7558 Intermediate Similarity NPD5363 Approved
0.7529 Intermediate Similarity NPD5362 Discontinued
0.7381 Intermediate Similarity NPD4822 Approved
0.7381 Intermediate Similarity NPD4820 Approved
0.7381 Intermediate Similarity NPD4819 Approved
0.7381 Intermediate Similarity NPD4821 Approved
0.7349 Intermediate Similarity NPD4268 Approved
0.7349 Intermediate Similarity NPD4271 Approved
0.7326 Intermediate Similarity NPD5332 Approved
0.7326 Intermediate Similarity NPD7154 Phase 3
0.7326 Intermediate Similarity NPD5331 Approved
0.7294 Intermediate Similarity NPD4790 Discontinued
0.7263 Intermediate Similarity NPD7640 Approved
0.7263 Intermediate Similarity NPD7639 Approved
0.7241 Intermediate Similarity NPD3666 Approved
0.7241 Intermediate Similarity NPD3665 Phase 1
0.7241 Intermediate Similarity NPD3133 Approved
0.7209 Intermediate Similarity NPD4269 Approved
0.7209 Intermediate Similarity NPD4270 Approved
0.7176 Intermediate Similarity NPD5790 Clinical (unspecified phase)
0.7159 Intermediate Similarity NPD1696 Phase 3
0.7158 Intermediate Similarity NPD4225 Approved
0.7158 Intermediate Similarity NPD7638 Approved
0.7143 Intermediate Similarity NPD5785 Approved
0.7108 Intermediate Similarity NPD3701 Clinical (unspecified phase)
0.7011 Intermediate Similarity NPD3667 Approved
0.6977 Remote Similarity NPD4252 Approved
0.6974 Remote Similarity NPD368 Approved
0.6941 Remote Similarity NPD7322 Clinical (unspecified phase)
0.6941 Remote Similarity NPD5784 Clinical (unspecified phase)
0.6889 Remote Similarity NPD7146 Approved
0.6889 Remote Similarity NPD6684 Approved
0.6889 Remote Similarity NPD3618 Phase 1
0.6889 Remote Similarity NPD6409 Approved
0.6889 Remote Similarity NPD5330 Approved
0.6889 Remote Similarity NPD7334 Approved
0.6889 Remote Similarity NPD7521 Approved
0.6889 Remote Similarity NPD5786 Approved
0.6882 Remote Similarity NPD7637 Suspended
0.686 Remote Similarity NPD4195 Approved
0.6854 Remote Similarity NPD4786 Approved
0.6818 Remote Similarity NPD4752 Clinical (unspecified phase)
0.6813 Remote Similarity NPD4751 Clinical (unspecified phase)
0.6786 Remote Similarity NPD7339 Approved
0.6786 Remote Similarity NPD6942 Approved
0.6782 Remote Similarity NPD7332 Phase 2
0.6778 Remote Similarity NPD6082 Clinical (unspecified phase)
0.6739 Remote Similarity NPD7513 Clinical (unspecified phase)
0.6739 Remote Similarity NPD6903 Approved
0.6705 Remote Similarity NPD5369 Approved
0.6703 Remote Similarity NPD4623 Approved
0.6703 Remote Similarity NPD4249 Approved
0.6703 Remote Similarity NPD5279 Phase 3
0.6703 Remote Similarity NPD4519 Discontinued
0.6702 Remote Similarity NPD6079 Approved
0.6702 Remote Similarity NPD7515 Phase 2
0.6701 Remote Similarity NPD6083 Phase 2
0.6701 Remote Similarity NPD6084 Phase 2
0.6667 Remote Similarity NPD5328 Approved
0.6667 Remote Similarity NPD6924 Approved
0.6667 Remote Similarity NPD4753 Phase 2
0.6667 Remote Similarity NPD6926 Approved
0.6667 Remote Similarity NPD5695 Phase 3
0.6667 Remote Similarity NPD6929 Approved
0.6667 Remote Similarity NPD6400 Clinical (unspecified phase)
0.6632 Remote Similarity NPD4202 Approved
0.6632 Remote Similarity NPD6399 Phase 3
0.663 Remote Similarity NPD4250 Approved
0.663 Remote Similarity NPD4251 Approved
0.6629 Remote Similarity NPD4221 Approved
0.6629 Remote Similarity NPD4223 Phase 3
0.6628 Remote Similarity NPD6925 Approved
0.6628 Remote Similarity NPD5776 Phase 2
0.6622 Remote Similarity NPD342 Phase 1
0.66 Remote Similarity NPD5211 Phase 2
0.66 Remote Similarity NPD7632 Discontinued
0.6593 Remote Similarity NPD1694 Approved
0.6591 Remote Similarity NPD7514 Phase 3
0.6591 Remote Similarity NPD6931 Approved
0.6591 Remote Similarity NPD6930 Phase 2
0.6591 Remote Similarity NPD5368 Approved
0.6588 Remote Similarity NPD8264 Approved
0.6585 Remote Similarity NPD6922 Approved
0.6585 Remote Similarity NPD6923 Approved
0.6552 Remote Similarity NPD7145 Approved
0.6526 Remote Similarity NPD5284 Approved
0.6526 Remote Similarity NPD5281 Approved
0.6522 Remote Similarity NPD5690 Phase 2
0.6517 Remote Similarity NPD6902 Approved
0.6517 Remote Similarity NPD6898 Phase 1
0.6512 Remote Similarity NPD6933 Approved
0.6506 Remote Similarity NPD7144 Approved
0.6506 Remote Similarity NPD7143 Approved
0.6505 Remote Similarity NPD5697 Approved
0.65 Remote Similarity NPD2685 Clinical (unspecified phase)
0.65 Remote Similarity NPD5344 Discontinued
0.6495 Remote Similarity NPD4629 Approved
0.6495 Remote Similarity NPD5210 Approved
0.6495 Remote Similarity NPD1698 Clinical (unspecified phase)
0.6489 Remote Similarity NPD6051 Approved
0.6484 Remote Similarity NPD4197 Approved
0.6471 Remote Similarity NPD5141 Approved
0.6465 Remote Similarity NPD5696 Approved
0.6458 Remote Similarity NPD5778 Approved
0.6458 Remote Similarity NPD5779 Approved
0.6444 Remote Similarity NPD6435 Approved
0.6442 Remote Similarity NPD6011 Approved
0.6442 Remote Similarity NPD6899 Approved
0.6442 Remote Similarity NPD6881 Approved
0.6429 Remote Similarity NPD7152 Approved
0.6429 Remote Similarity NPD7150 Approved
0.6429 Remote Similarity NPD5222 Approved
0.6429 Remote Similarity NPD5220 Clinical (unspecified phase)
0.6429 Remote Similarity NPD5221 Approved
0.6429 Remote Similarity NPD7151 Approved
0.6429 Remote Similarity NPD4792 Clinical (unspecified phase)
0.6422 Remote Similarity NPD7115 Discovery
0.6421 Remote Similarity NPD7838 Discovery
0.6421 Remote Similarity NPD6698 Approved
0.6421 Remote Similarity NPD46 Approved
0.6413 Remote Similarity NPD7520 Clinical (unspecified phase)
0.6413 Remote Similarity NPD5329 Approved
0.6408 Remote Similarity NPD5739 Approved
0.6408 Remote Similarity NPD7128 Approved
0.6408 Remote Similarity NPD6402 Approved
0.6408 Remote Similarity NPD6675 Approved
0.6404 Remote Similarity NPD4695 Discontinued
0.6404 Remote Similarity NPD7525 Registered
0.6404 Remote Similarity NPD7509 Discontinued
0.64 Remote Similarity NPD5286 Approved
0.64 Remote Similarity NPD5285 Approved
0.64 Remote Similarity NPD4696 Approved
0.64 Remote Similarity NPD6404 Discontinued
0.6392 Remote Similarity NPD7748 Approved
0.6383 Remote Similarity NPD5737 Approved
0.6383 Remote Similarity NPD6672 Approved
0.6381 Remote Similarity NPD6012 Approved
0.6381 Remote Similarity NPD6013 Approved
0.6381 Remote Similarity NPD6014 Approved
0.6374 Remote Similarity NPD4788 Approved
0.6374 Remote Similarity NPD6695 Phase 3
0.6373 Remote Similarity NPD6647 Phase 2
0.6364 Remote Similarity NPD4755 Approved
0.6364 Remote Similarity NPD5173 Approved
0.6355 Remote Similarity NPD6053 Discontinued
0.6346 Remote Similarity NPD5701 Approved
0.6344 Remote Similarity NPD5205 Approved
0.6344 Remote Similarity NPD4138 Approved
0.6344 Remote Similarity NPD4690 Approved
0.6344 Remote Similarity NPD4689 Approved
0.6344 Remote Similarity NPD4688 Approved
0.6344 Remote Similarity NPD4694 Approved
0.6344 Remote Similarity NPD4693 Phase 3
0.6344 Remote Similarity NPD5280 Approved
0.6337 Remote Similarity NPD5223 Approved
0.6329 Remote Similarity NPD4193 Approved
0.6329 Remote Similarity NPD4194 Approved
0.6329 Remote Similarity NPD4191 Approved
0.6329 Remote Similarity NPD4192 Approved
0.6321 Remote Similarity NPD6883 Approved
0.6321 Remote Similarity NPD7290 Approved
0.6321 Remote Similarity NPD7102 Approved
0.6316 Remote Similarity NPD1695 Approved
0.6304 Remote Similarity NPD3668 Phase 3
0.6304 Remote Similarity NPD7338 Clinical (unspecified phase)
0.63 Remote Similarity NPD8029 Clinical (unspecified phase)
0.6286 Remote Similarity NPD7320 Approved
0.6286 Remote Similarity NPD6686 Approved
0.6279 Remote Similarity NPD4785 Approved
0.6279 Remote Similarity NPD4784 Approved
0.6275 Remote Similarity NPD5225 Approved
0.6275 Remote Similarity NPD5224 Approved
0.6275 Remote Similarity NPD4633 Approved
0.6275 Remote Similarity NPD5226 Approved
0.6264 Remote Similarity NPD5209 Approved
0.6263 Remote Similarity NPD4697 Phase 3
0.6262 Remote Similarity NPD8130 Phase 1
0.6262 Remote Similarity NPD6847 Approved
0.6262 Remote Similarity NPD6649 Approved
0.6262 Remote Similarity NPD6869 Approved
0.6262 Remote Similarity NPD6650 Approved
0.6262 Remote Similarity NPD6617 Approved
0.625 Remote Similarity NPD6932 Approved
0.625 Remote Similarity NPD4756 Discovery
0.6238 Remote Similarity NPD6648 Approved
0.6238 Remote Similarity NPD4700 Approved
0.6237 Remote Similarity NPD6893 Approved
0.6235 Remote Similarity NPD4243 Approved
0.6226 Remote Similarity NPD6372 Approved
0.6226 Remote Similarity NPD6373 Approved
0.6222 Remote Similarity NPD4748 Discontinued
0.6214 Remote Similarity NPD5175 Approved
0.6214 Remote Similarity NPD5174 Approved
0.6211 Remote Similarity NPD5208 Approved
0.6204 Remote Similarity NPD8297 Approved
0.6204 Remote Similarity NPD6882 Approved
0.6203 Remote Similarity NPD4246 Clinical (unspecified phase)
0.62 Remote Similarity NPD7902 Approved
0.619 Remote Similarity NPD7899 Clinical (unspecified phase)
0.6186 Remote Similarity NPD4810 Clinical (unspecified phase)

Structure

External Identifiers

PubChem CID   6537505
ChEMBL   CHEMBL1565922
ZINC  

Physicochemical Properties

Molecular Weight:  250.16
ALogP:  1.5207
MLogP:  2.78
XLogP:  1.81
# Rotatable Bonds:  7
Polar Surface Area:  57.53
# H-Bond Aceptor:  3
# H-Bond Donor:  2
# Rings:  2
# Heavy Atoms:  18

Download Data

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General Info & Identifiers & Properties  
Structure MOL file  
Source Organisms  
Biological Activities  
Similar NPs/Drugs