Drug Information

Drug ID:  NPD7320
Drug Name:  Hydrocortisone Cypionate
Molecular Formula:  C29H42O6
Canonical SMILES:  O=C(OCC(=O)[C@@]1(O)CC[C@@H]2[C@]1(C)C[C@H](O)[C@H]1[C@H]2CCC2=CC(=O)CC[C@]12C)CCC1CCCC1
Standard InCHI:  InChI=1S/C29H42O6/c1-27-13-11-20(30)15-19(27)8-9-21-22-12-14-29(34,28(22,2)16-23(31)26(21)27)24(32)17-35-25(33)10-7-18-5-3-4-6-18/h15,18,21-23,26,31,34H,3-14,16-17H2,1-2H3/t21-,22-,23-,26+,27-,28-,29-/m0/s1
Standard InCHIKey:  DLVOSEUFIRPIRM-KAQKJVHQSA-N
Max Developmental Stage:  Approved
Max Developmental Stage Source:  ChEMBL

  Structural Similarity Between NPASS Natural Products and NPD7320

Similarity level is defined by Tanimoto coefficient (Tc) between two molecules. Tc lies between [0, 1] where '1' indicates the highest similarity. What is Tanimoto coefficient
Tanimoto coefficient is calculated based on PubChem 881-bit substructure fingerprints.


  Similar Natural Products

High Similarity Level: Tc>=0.85; Intermediate Similarity Level: 0.7 <= Tc < 0.85; Remote Similarity Level: 0.65 <= Tc < 0.7

Similarity Level Similarity Score Natural Product ID
High Similarity 0.9505 NPC44063
High Similarity 0.932 NPC2766
High Similarity 0.9143 NPC43775
High Similarity 0.9091 NPC18509
High Similarity 0.8922 NPC22388
High Similarity 0.8911 NPC144956
High Similarity 0.8762 NPC220974
High Similarity 0.875 NPC235889
High Similarity 0.875 NPC137657
High Similarity 0.8704 NPC71348
High Similarity 0.8679 NPC94529
High Similarity 0.8667 NPC181265
High Similarity 0.8667 NPC196528
High Similarity 0.8654 NPC140723
High Similarity 0.8636 NPC270958
High Similarity 0.8624 NPC52634
High Similarity 0.8624 NPC194100
High Similarity 0.8624 NPC202889
High Similarity 0.8614 NPC305483
High Similarity 0.8614 NPC328162
High Similarity 0.8614 NPC96859
High Similarity 0.8586 NPC185936
High Similarity 0.8586 NPC168027
High Similarity 0.8571 NPC29705
High Similarity 0.8559 NPC471854
High Similarity 0.8558 NPC308726
High Similarity 0.8558 NPC119601
High Similarity 0.8558 NPC473928
High Similarity 0.8532 NPC475524
High Similarity 0.8532 NPC100267
High Similarity 0.8532 NPC280782
High Similarity 0.8519 NPC197428
High Similarity 0.8515 NPC317586
High Similarity 0.8515 NPC477438
High Similarity 0.8515 NPC470016
High Similarity 0.8515 NPC477437
High Similarity 0.8515 NPC469599
High Similarity 0.8509 NPC222688
High Similarity 0.85 NPC477435
High Similarity 0.85 NPC470375
High Similarity 0.85 NPC477436
High Similarity 0.85 NPC470376
High Similarity 0.85 NPC109414
Intermediate Similarity 0.8496 NPC109973
Intermediate Similarity 0.8491 NPC231530
Intermediate Similarity 0.8491 NPC278628
Intermediate Similarity 0.8485 NPC171441
Intermediate Similarity 0.8482 NPC257457
Intermediate Similarity 0.8482 NPC118638
Intermediate Similarity 0.8482 NPC311554
Intermediate Similarity 0.8468 NPC266728
Intermediate Similarity 0.8468 NPC49492
Intermediate Similarity 0.8462 NPC163372
Intermediate Similarity 0.8462 NPC302537
Intermediate Similarity 0.8455 NPC250109
Intermediate Similarity 0.8455 NPC962
Intermediate Similarity 0.8447 NPC477854
Intermediate Similarity 0.844 NPC231589
Intermediate Similarity 0.844 NPC214797
Intermediate Similarity 0.844 NPC118860
Intermediate Similarity 0.8431 NPC49371
Intermediate Similarity 0.8426 NPC304495
Intermediate Similarity 0.8426 NPC241927
Intermediate Similarity 0.8426 NPC475941
Intermediate Similarity 0.8426 NPC474901
Intermediate Similarity 0.8426 NPC258543
Intermediate Similarity 0.8421 NPC470921
Intermediate Similarity 0.8416 NPC477439
Intermediate Similarity 0.8416 NPC166906
Intermediate Similarity 0.8416 NPC111015
Intermediate Similarity 0.8411 NPC475294
Intermediate Similarity 0.84 NPC154101
Intermediate Similarity 0.8396 NPC472227
Intermediate Similarity 0.8396 NPC471293
Intermediate Similarity 0.8396 NPC472228
Intermediate Similarity 0.8384 NPC310010
Intermediate Similarity 0.8384 NPC305039
Intermediate Similarity 0.8384 NPC475921
Intermediate Similarity 0.8384 NPC474704
Intermediate Similarity 0.8384 NPC326627
Intermediate Similarity 0.8381 NPC136289
Intermediate Similarity 0.8381 NPC308351
Intermediate Similarity 0.8381 NPC271266
Intermediate Similarity 0.8365 NPC476274
Intermediate Similarity 0.8365 NPC15390
Intermediate Similarity 0.8365 NPC472972
Intermediate Similarity 0.8365 NPC83709
Intermediate Similarity 0.8364 NPC207251
Intermediate Similarity 0.8364 NPC170487
Intermediate Similarity 0.8362 NPC473255
Intermediate Similarity 0.835 NPC43747
Intermediate Similarity 0.8349 NPC6206
Intermediate Similarity 0.8333 NPC184848
Intermediate Similarity 0.8333 NPC69548
Intermediate Similarity 0.8318 NPC265127
Intermediate Similarity 0.8318 NPC475571
Intermediate Similarity 0.8318 NPC60681
Intermediate Similarity 0.8317 NPC470224
Intermediate Similarity 0.8304 NPC148458
Intermediate Similarity 0.8302 NPC236390
Intermediate Similarity 0.8302 NPC311612
Intermediate Similarity 0.8302 NPC191892
Intermediate Similarity 0.8302 NPC70967
Intermediate Similarity 0.8302 NPC112009
Intermediate Similarity 0.8302 NPC33973
Intermediate Similarity 0.8302 NPC36321
Intermediate Similarity 0.83 NPC471896
Intermediate Similarity 0.8286 NPC224720
Intermediate Similarity 0.8286 NPC476240
Intermediate Similarity 0.8286 NPC477052
Intermediate Similarity 0.8286 NPC474327
Intermediate Similarity 0.8286 NPC477053
Intermediate Similarity 0.8286 NPC477051
Intermediate Similarity 0.8286 NPC476223
Intermediate Similarity 0.8286 NPC81530
Intermediate Similarity 0.8283 NPC328539
Intermediate Similarity 0.8269 NPC477813
Intermediate Similarity 0.8269 NPC176845
Intermediate Similarity 0.8269 NPC114274
Intermediate Similarity 0.8257 NPC10064
Intermediate Similarity 0.8257 NPC41405
Intermediate Similarity 0.8257 NPC170221
Intermediate Similarity 0.8257 NPC214644
Intermediate Similarity 0.8252 NPC173272
Intermediate Similarity 0.8252 NPC95565
Intermediate Similarity 0.8252 NPC192428
Intermediate Similarity 0.8252 NPC477853
Intermediate Similarity 0.8241 NPC185
Intermediate Similarity 0.8241 NPC59530
Intermediate Similarity 0.8241 NPC83744
Intermediate Similarity 0.8235 NPC245972
Intermediate Similarity 0.8235 NPC196485
Intermediate Similarity 0.823 NPC239273
Intermediate Similarity 0.8224 NPC216245
Intermediate Similarity 0.8224 NPC2436
Intermediate Similarity 0.8224 NPC13385
Intermediate Similarity 0.8224 NPC149124
Intermediate Similarity 0.8224 NPC75531
Intermediate Similarity 0.8224 NPC135854
Intermediate Similarity 0.8224 NPC470251
Intermediate Similarity 0.822 NPC470882
Intermediate Similarity 0.822 NPC473253
Intermediate Similarity 0.822 NPC473265
Intermediate Similarity 0.8218 NPC23434
Intermediate Similarity 0.8214 NPC326542
Intermediate Similarity 0.8214 NPC473798
Intermediate Similarity 0.8208 NPC477915
Intermediate Similarity 0.8208 NPC204450
Intermediate Similarity 0.8208 NPC477054
Intermediate Similarity 0.8208 NPC185530
Intermediate Similarity 0.8208 NPC195290
Intermediate Similarity 0.8208 NPC87351
Intermediate Similarity 0.82 NPC31985
Intermediate Similarity 0.82 NPC86319
Intermediate Similarity 0.82 NPC1015
Intermediate Similarity 0.82 NPC477943
Intermediate Similarity 0.82 NPC275740
Intermediate Similarity 0.82 NPC474245
Intermediate Similarity 0.82 NPC76879
Intermediate Similarity 0.8198 NPC147180
Intermediate Similarity 0.8198 NPC475970
Intermediate Similarity 0.8198 NPC264634
Intermediate Similarity 0.8198 NPC221144
Intermediate Similarity 0.819 NPC154072
Intermediate Similarity 0.819 NPC316964
Intermediate Similarity 0.819 NPC474720
Intermediate Similarity 0.819 NPC88198
Intermediate Similarity 0.819 NPC313528
Intermediate Similarity 0.819 NPC218383
Intermediate Similarity 0.8182 NPC142361
Intermediate Similarity 0.8182 NPC474684
Intermediate Similarity 0.8182 NPC163314
Intermediate Similarity 0.8182 NPC272898
Intermediate Similarity 0.8182 NPC473036
Intermediate Similarity 0.8182 NPC5284
Intermediate Similarity 0.8182 NPC235077
Intermediate Similarity 0.8173 NPC18319
Intermediate Similarity 0.8173 NPC190554
Intermediate Similarity 0.8173 NPC470834
Intermediate Similarity 0.8173 NPC57416
Intermediate Similarity 0.8173 NPC108078
Intermediate Similarity 0.8173 NPC23680
Intermediate Similarity 0.8173 NPC69385
Intermediate Similarity 0.8173 NPC107243
Intermediate Similarity 0.8173 NPC475894
Intermediate Similarity 0.8165 NPC469844
Intermediate Similarity 0.8165 NPC177064
Intermediate Similarity 0.8165 NPC329417
Intermediate Similarity 0.8155 NPC139570
Intermediate Similarity 0.8155 NPC45324
Intermediate Similarity 0.8155 NPC162001
Intermediate Similarity 0.8155 NPC48330
Intermediate Similarity 0.8155 NPC279974
Intermediate Similarity 0.8155 NPC473170
Intermediate Similarity 0.8155 NPC222845
Intermediate Similarity 0.8148 NPC171137
Intermediate Similarity 0.8148 NPC152695
Intermediate Similarity 0.8148 NPC202167
Intermediate Similarity 0.8148 NPC85829
Intermediate Similarity 0.8148 NPC302607

Drug Structure

External Identifiers

TTD  
DrugBank  
ChEMBL  
IUPHAR/BPS  
PharmaGKB  
KEGG Drug  
PubChem CID  
ChEBI  
CAS Number  

Drug Properties

Molecular Weight  486.30
ALogP  -0.8329
MLogP  3.99
XLogP  3.561
HDA  6
HBD  2
Rotatable Bonds  11
TPSA  100.9
RO5 Violation  0