Target ID | Target Type | Target Name | Target Organism | Activity Type | Activity Relation | Value | Unit | Reference |
---|---|---|---|---|---|---|---|---|
NPT393 | Cell Line | HCT-116 | Homo sapiens | GI | = | 3 | % | 17958396 |
NPT2 | Others | Unspecified | MIC | > | 188000 | nM | 23073993 | |
NPT564 | Organism | Listeria monocytogenes | Listeria monocytogenes | MIC | > | 188000 | nM | 22070654 |
NPT4428 | Organism | Staphylococcus sciuri | Staphylococcus sciuri | MIC | > | 188000 | nM | 25993496 |
NPT16 | Organism | Staphylococcus aureus | Staphylococcus aureus | MIC | > | 188000 | nM | 18163588 |
NPT16 | Organism | Staphylococcus aureus | Staphylococcus aureus | MIC | > | 188000 | nM | PubChem BioAssay data set |
NPT1531 | Organism | Enterococcus faecium | Enterococcus faecium | MIC | = | 50000 | nM | DrugMatrix in vitro pharmacology data |
NPT564 | Organism | Listeria monocytogenes | Listeria monocytogenes | MIC | > | 188000 | nM | 10.6019/CHEMBL1201861 |
NPT314 | Organism | Bacillus cereus | Bacillus cereus | MIC | <= | 188000 | nM | 10.6019/CHEMBL1201861 |
NPT4844 | Organism | Enterococcus gallinarum | Enterococcus gallinarum | MIC | > | 188000 | nM | 12880316 |
NPT3145 | Organism | Bacillus subtilis subsp. spizizenii ATCC 6633 | Bacillus subtilis subsp. spizizenii ATCC 6633 | MIC | > | 188000 | nM | 10479316 |
NPT1531 | Organism | Enterococcus faecium | Enterococcus faecium | MIC | = | 50000 | nM | 18800848 |
NPT16 | Organism | Staphylococcus aureus | Staphylococcus aureus | MIC | > | 188000 | nM | 23819826 |
NPT1531 | Organism | Enterococcus faecium | Enterococcus faecium | MIC | > | 188000 | nM | 18824352 |
NPT4840 | Organism | Staphylococcus lugdunensis | Staphylococcus lugdunensis | MIC | > | 188000 | nM | 20713660 |
NPT4844 | Organism | Enterococcus gallinarum | Enterococcus gallinarum | MIC | > | 188000 | nM | DrugMatrix in vitro pharmacology data |
NPT314 | Organism | Bacillus cereus | Bacillus cereus | MIC | <= | 188000 | nM | 16643037 |
NPT314 | Organism | Bacillus cereus | Bacillus cereus | MIC | <= | 188000 | nM | 16643032 |
NPT2 | Others | Unspecified | MIC | = | 50000 | nM | 16417306 | |
NPT175 | Organism | Enterococcus faecalis | Enterococcus faecalis | MIC | = | 50000 | nM | 10.1584/jpestics.16.271 |
NPT1531 | Organism | Enterococcus faecium | Enterococcus faecium | MIC | <= | 188000 | nM | 17970595 |
NPT16 | Organism | Staphylococcus aureus | Staphylococcus aureus | MIC | > | 188000 | nM | 24645629 |
NPT1477 | Organism | Staphylococcus haemolyticus | Staphylococcus haemolyticus | MIC | > | 188000 | nM | 10395485 |
NPT1531 | Organism | Enterococcus faecium | Enterococcus faecium | MIC | > | 188000 | nM | Open TG-GATES in vivo data: Biochemistry |
NPT175 | Organism | Enterococcus faecalis | Enterococcus faecalis | MIC | = | 50000 | nM | 23691952 |
NPT314 | Organism | Bacillus cereus | Bacillus cereus | MIC | <= | 188000 | nM | 1593286 |
NPT171 | Cell Line | MRC5 | Homo sapiens | GI | = | 86 | % | 24571273 |
NPT4844 | Organism | Enterococcus gallinarum | Enterococcus gallinarum | MIC | > | 188000 | nM | 11170658 |
NPT175 | Organism | Enterococcus faecalis | Enterococcus faecalis | MIC | = | 50000 | nM | 12398543 |
NPT564 | Organism | Listeria monocytogenes | Listeria monocytogenes | MIC | > | 188000 | nM | 20086162 |
NPT1531 | Organism | Enterococcus faecium | Enterococcus faecium | MIC | = | 50000 | nM | 22055713 |
NPT4843 | Organism | Corynebacterium striatum | Corynebacterium striatum | MIC | > | 188000 | nM | 23398362 |
NPT17 | Organism | Staphylococcus epidermidis | Staphylococcus epidermidis | MIC | > | 188000 | nM | 12670149 |
NPT1863 | Organism | Staphylococcus saprophyticus | Staphylococcus saprophyticus | MIC | > | 188000 | nM | 9322362 |
NPT2 | Others | Unspecified | MIC | > | 188000 | nM | 24216090 | |
NPT4839 | Organism | Staphylococcus intermedius | Staphylococcus intermedius | MIC | > | 188000 | nM | DrugMatrix in vitro pharmacology data |
NPT4845 | Organism | Listeria innocua | Listeria innocua | MIC | > | 188000 | nM | 24472146 |
NPT175 | Organism | Enterococcus faecalis | Enterococcus faecalis | MIC | = | 50000 | nM | 9213587 |
NPT171 | Cell Line | MRC5 | Homo sapiens | GI | = | 34 | % | 15646539 |
NPT393 | Cell Line | HCT-116 | Homo sapiens | GI | = | 68 | % | 15646539 |
NPT3730 | Organism | Enterococcus durans | Enterococcus durans | MIC | = | 50000 | nM | 11473413 |
NPT564 | Organism | Listeria monocytogenes | Listeria monocytogenes | MIC | > | 188000 | nM | 10924166 |
NPT16 | Organism | Staphylococcus aureus | Staphylococcus aureus | MIC | > | 188000 | nM | 19072548 |
NPT16 | Organism | Staphylococcus aureus | Staphylococcus aureus | MIC | > | 188000 | nM | 11473413 |
NPT1863 | Organism | Staphylococcus saprophyticus | Staphylococcus saprophyticus | MIC | > | 188000 | nM | 22148431 |
NPT4075 | Organism | Enterococcus avium | Enterococcus avium | MIC | > | 188000 | nM | 15974580 |
NPT175 | Organism | Enterococcus faecalis | Enterococcus faecalis | MIC | = | 50000 | nM | DrugMatrix in vivo data: Pathology |
NPT3721 | Organism | Enterococcus hirae | Enterococcus hirae | MIC | > | 188000 | nM | 20585136 |
Similarity level is defined by Tanimoto coefficient (Tc) between two molecules. Tc lies between [0, 1] where '1' indicates the highest similarity. What is Tanimoto coefficient
●  The left chart: Distribution of similarity level between NPC311070 and all remaining natural products in the NPASS database.
●  The right table: Most similar natural products (Tc>=0.56 or Top200).
Similarity Score | Similarity Level | Natural Product ID |
---|---|---|
0.939 | High Similarity | NPC472810 |
0.939 | High Similarity | NPC472809 |
0.9383 | High Similarity | NPC131813 |
0.925 | High Similarity | NPC42476 |
0.9167 | High Similarity | NPC78973 |
0.9059 | High Similarity | NPC177037 |
0.9059 | High Similarity | NPC472814 |
0.9048 | High Similarity | NPC470734 |
0.9012 | High Similarity | NPC472377 |
0.8953 | High Similarity | NPC472812 |
0.8941 | High Similarity | NPC182136 |
0.8851 | High Similarity | NPC469697 |
0.8837 | High Similarity | NPC472811 |
0.8824 | High Similarity | NPC50488 |
0.8824 | High Similarity | NPC474396 |
0.8795 | High Similarity | NPC86316 |
0.8795 | High Similarity | NPC106416 |
0.8795 | High Similarity | NPC471795 |
0.8795 | High Similarity | NPC473251 |
0.8795 | High Similarity | NPC42586 |
0.875 | High Similarity | NPC242767 |
0.8736 | High Similarity | NPC205034 |
0.8736 | High Similarity | NPC115021 |
0.8736 | High Similarity | NPC139692 |
0.8736 | High Similarity | NPC152778 |
0.8736 | High Similarity | NPC162615 |
0.8736 | High Similarity | NPC53555 |
0.8721 | High Similarity | NPC310479 |
0.8721 | High Similarity | NPC221111 |
0.8721 | High Similarity | NPC280149 |
0.8706 | High Similarity | NPC474629 |
0.8706 | High Similarity | NPC472378 |
0.869 | High Similarity | NPC329692 |
0.8652 | High Similarity | NPC134072 |
0.8652 | High Similarity | NPC242848 |
0.8652 | High Similarity | NPC234993 |
0.8652 | High Similarity | NPC162346 |
0.8642 | High Similarity | NPC281880 |
0.8636 | High Similarity | NPC298973 |
0.8636 | High Similarity | NPC470255 |
0.8636 | High Similarity | NPC104925 |
0.8621 | High Similarity | NPC72845 |
0.8621 | High Similarity | NPC329842 |
0.8605 | High Similarity | NPC174342 |
0.8588 | High Similarity | NPC312561 |
0.8588 | High Similarity | NPC471796 |
0.8588 | High Similarity | NPC166857 |
0.8571 | High Similarity | NPC30984 |
0.8571 | High Similarity | NPC65661 |
0.8556 | High Similarity | NPC477718 |
0.8556 | High Similarity | NPC477719 |
0.8556 | High Similarity | NPC475709 |
0.8554 | High Similarity | NPC79945 |
0.8554 | High Similarity | NPC474809 |
0.8539 | High Similarity | NPC472441 |
0.8539 | High Similarity | NPC276110 |
0.8537 | High Similarity | NPC170303 |
0.8537 | High Similarity | NPC159148 |
0.8537 | High Similarity | NPC475944 |
0.8506 | High Similarity | NPC477782 |
0.8506 | High Similarity | NPC51486 |
0.85 | High Similarity | NPC189206 |
0.85 | High Similarity | NPC262747 |
0.8471 | Intermediate Similarity | NPC471219 |
0.8462 | Intermediate Similarity | NPC275086 |
0.8462 | Intermediate Similarity | NPC325229 |
0.8452 | Intermediate Similarity | NPC96055 |
0.8444 | Intermediate Similarity | NPC16967 |
0.8444 | Intermediate Similarity | NPC473153 |
0.8427 | Intermediate Similarity | NPC105490 |
0.8427 | Intermediate Similarity | NPC191521 |
0.8427 | Intermediate Similarity | NPC57117 |
0.8415 | Intermediate Similarity | NPC10636 |
0.8409 | Intermediate Similarity | NPC477783 |
0.8395 | Intermediate Similarity | NPC474816 |
0.8395 | Intermediate Similarity | NPC209135 |
0.8391 | Intermediate Similarity | NPC251528 |
0.8391 | Intermediate Similarity | NPC5509 |
0.8372 | Intermediate Similarity | NPC473891 |
0.837 | Intermediate Similarity | NPC477716 |
0.837 | Intermediate Similarity | NPC38855 |
0.837 | Intermediate Similarity | NPC477721 |
0.8353 | Intermediate Similarity | NPC474013 |
0.8352 | Intermediate Similarity | NPC51499 |
0.8333 | Intermediate Similarity | NPC476927 |
0.8315 | Intermediate Similarity | NPC472640 |
0.8315 | Intermediate Similarity | NPC472641 |
0.8315 | Intermediate Similarity | NPC7349 |
0.8295 | Intermediate Similarity | NPC472642 |
0.8295 | Intermediate Similarity | NPC281942 |
0.8295 | Intermediate Similarity | NPC232426 |
0.828 | Intermediate Similarity | NPC477717 |
0.8276 | Intermediate Similarity | NPC93411 |
0.8261 | Intermediate Similarity | NPC159763 |
0.8261 | Intermediate Similarity | NPC278386 |
0.8261 | Intermediate Similarity | NPC278673 |
0.8261 | Intermediate Similarity | NPC124512 |
0.8261 | Intermediate Similarity | NPC474440 |
0.8242 | Intermediate Similarity | NPC165632 |
0.8235 | Intermediate Similarity | NPC102048 |
0.8235 | Intermediate Similarity | NPC471302 |
0.8235 | Intermediate Similarity | NPC306951 |
0.8235 | Intermediate Similarity | NPC32223 |
0.8222 | Intermediate Similarity | NPC324078 |
0.8214 | Intermediate Similarity | NPC200513 |
0.8214 | Intermediate Similarity | NPC256112 |
0.8214 | Intermediate Similarity | NPC155521 |
0.8214 | Intermediate Similarity | NPC471218 |
0.8214 | Intermediate Similarity | NPC471298 |
0.8214 | Intermediate Similarity | NPC2524 |
0.8202 | Intermediate Similarity | NPC141831 |
0.8202 | Intermediate Similarity | NPC477122 |
0.8191 | Intermediate Similarity | NPC475038 |
0.8191 | Intermediate Similarity | NPC109195 |
0.8191 | Intermediate Similarity | NPC472815 |
0.8182 | Intermediate Similarity | NPC79027 |
0.8172 | Intermediate Similarity | NPC16601 |
0.8172 | Intermediate Similarity | NPC324841 |
0.8171 | Intermediate Similarity | NPC184737 |
0.8152 | Intermediate Similarity | NPC231751 |
0.8152 | Intermediate Similarity | NPC73911 |
0.8152 | Intermediate Similarity | NPC474343 |
0.8132 | Intermediate Similarity | NPC209355 |
0.8118 | Intermediate Similarity | NPC321385 |
0.8118 | Intermediate Similarity | NPC474193 |
0.8118 | Intermediate Similarity | NPC471297 |
0.8118 | Intermediate Similarity | NPC477124 |
0.8118 | Intermediate Similarity | NPC23748 |
0.8118 | Intermediate Similarity | NPC12283 |
0.8111 | Intermediate Similarity | NPC472303 |
0.8105 | Intermediate Similarity | NPC471938 |
0.8095 | Intermediate Similarity | NPC40228 |
0.8095 | Intermediate Similarity | NPC229584 |
0.8095 | Intermediate Similarity | NPC14203 |
0.8085 | Intermediate Similarity | NPC303559 |
0.8085 | Intermediate Similarity | NPC11974 |
0.8072 | Intermediate Similarity | NPC80471 |
0.8072 | Intermediate Similarity | NPC5908 |
0.8072 | Intermediate Similarity | NPC100906 |
0.8072 | Intermediate Similarity | NPC110373 |
0.8068 | Intermediate Similarity | NPC104560 |
0.8068 | Intermediate Similarity | NPC291665 |
0.8049 | Intermediate Similarity | NPC132542 |
0.8049 | Intermediate Similarity | NPC283619 |
0.8046 | Intermediate Similarity | NPC475069 |
0.8046 | Intermediate Similarity | NPC175145 |
0.8023 | Intermediate Similarity | NPC474693 |
0.8023 | Intermediate Similarity | NPC318515 |
0.8023 | Intermediate Similarity | NPC126518 |
0.8023 | Intermediate Similarity | NPC471301 |
0.8022 | Intermediate Similarity | NPC201725 |
0.8022 | Intermediate Similarity | NPC474554 |
0.8021 | Intermediate Similarity | NPC471937 |
0.8 | Intermediate Similarity | NPC476081 |
0.8 | Intermediate Similarity | NPC78594 |
0.8 | Intermediate Similarity | NPC323251 |
0.8 | Intermediate Similarity | NPC471914 |
0.8 | Intermediate Similarity | NPC234335 |
0.8 | Intermediate Similarity | NPC289479 |
0.7979 | Intermediate Similarity | NPC117685 |
0.7979 | Intermediate Similarity | NPC472826 |
0.7979 | Intermediate Similarity | NPC476767 |
0.7979 | Intermediate Similarity | NPC201406 |
0.7979 | Intermediate Similarity | NPC251680 |
0.7979 | Intermediate Similarity | NPC474012 |
0.7979 | Intermediate Similarity | NPC476299 |
0.7978 | Intermediate Similarity | NPC262858 |
0.7978 | Intermediate Similarity | NPC82876 |
0.7978 | Intermediate Similarity | NPC146554 |
0.7978 | Intermediate Similarity | NPC472240 |
0.7978 | Intermediate Similarity | NPC473647 |
0.7976 | Intermediate Similarity | NPC469802 |
0.7976 | Intermediate Similarity | NPC268827 |
0.7957 | Intermediate Similarity | NPC208094 |
0.7957 | Intermediate Similarity | NPC253826 |
0.7957 | Intermediate Similarity | NPC205143 |
0.7957 | Intermediate Similarity | NPC53844 |
0.7952 | Intermediate Similarity | NPC239098 |
0.7938 | Intermediate Similarity | NPC472818 |
0.7935 | Intermediate Similarity | NPC471915 |
0.7935 | Intermediate Similarity | NPC111273 |
0.7931 | Intermediate Similarity | NPC476602 |
0.7931 | Intermediate Similarity | NPC472442 |
0.7931 | Intermediate Similarity | NPC163606 |
0.7931 | Intermediate Similarity | NPC35933 |
0.7931 | Intermediate Similarity | NPC475860 |
0.7931 | Intermediate Similarity | NPC473659 |
0.7931 | Intermediate Similarity | NPC109528 |
0.7931 | Intermediate Similarity | NPC329630 |
0.7931 | Intermediate Similarity | NPC52628 |
0.7931 | Intermediate Similarity | NPC189311 |
0.7931 | Intermediate Similarity | NPC474694 |
0.7917 | Intermediate Similarity | NPC187302 |
0.7917 | Intermediate Similarity | NPC97487 |
0.7917 | Intermediate Similarity | NPC120321 |
0.7917 | Intermediate Similarity | NPC112009 |
0.7917 | Intermediate Similarity | NPC10232 |
0.7917 | Intermediate Similarity | NPC196471 |
0.7917 | Intermediate Similarity | NPC45897 |
0.7917 | Intermediate Similarity | NPC189588 |
Similarity level is defined by Tanimoto coefficient (Tc) between two molecules.
●  The left chart: Distribution of similarity level between NPC311070 and all drugs/candidates.
●  The right table: Most similar clinical/approved drugs (Tc>=0.56 or Top200).
Similarity Score | Similarity Level | Drug ID | Developmental Stage |
---|---|---|---|
0.8261 | Intermediate Similarity | NPD4225 | Approved |
0.8214 | Intermediate Similarity | NPD4752 | Clinical (unspecified phase) |
0.8023 | Intermediate Similarity | NPD6400 | Clinical (unspecified phase) |
0.7979 | Intermediate Similarity | NPD7640 | Approved |
0.7979 | Intermediate Similarity | NPD7639 | Approved |
0.7872 | Intermediate Similarity | NPD7638 | Approved |
0.76 | Intermediate Similarity | NPD6686 | Approved |
0.7419 | Intermediate Similarity | NPD7637 | Suspended |
0.7391 | Intermediate Similarity | NPD6051 | Approved |
0.7303 | Intermediate Similarity | NPD6695 | Phase 3 |
0.7273 | Intermediate Similarity | NPD7632 | Discontinued |
0.7253 | Intermediate Similarity | NPD6409 | Approved |
0.7253 | Intermediate Similarity | NPD5330 | Approved |
0.7253 | Intermediate Similarity | NPD6684 | Approved |
0.7253 | Intermediate Similarity | NPD7146 | Approved |
0.7253 | Intermediate Similarity | NPD7334 | Approved |
0.7253 | Intermediate Similarity | NPD7521 | Approved |
0.7241 | Intermediate Similarity | NPD6929 | Approved |
0.7222 | Intermediate Similarity | NPD3133 | Approved |
0.7222 | Intermediate Similarity | NPD3665 | Phase 1 |
0.7222 | Intermediate Similarity | NPD7338 | Clinical (unspecified phase) |
0.7222 | Intermediate Similarity | NPD3666 | Approved |
0.7216 | Intermediate Similarity | NPD6083 | Phase 2 |
0.7216 | Intermediate Similarity | NPD6084 | Phase 2 |
0.7159 | Intermediate Similarity | NPD6931 | Approved |
0.7159 | Intermediate Similarity | NPD6930 | Phase 2 |
0.7143 | Intermediate Similarity | NPD1694 | Approved |
0.7125 | Intermediate Similarity | NPD2685 | Clinical (unspecified phase) |
0.7097 | Intermediate Similarity | NPD7513 | Clinical (unspecified phase) |
0.7097 | Intermediate Similarity | NPD6903 | Approved |
0.7093 | Intermediate Similarity | NPD3701 | Clinical (unspecified phase) |
0.7083 | Intermediate Similarity | NPD7748 | Approved |
0.7065 | Intermediate Similarity | NPD3618 | Phase 1 |
0.7059 | Intermediate Similarity | NPD6924 | Approved |
0.7059 | Intermediate Similarity | NPD6926 | Approved |
0.7053 | Intermediate Similarity | NPD7515 | Phase 2 |
0.7045 | Intermediate Similarity | NPD7645 | Phase 2 |
0.7037 | Intermediate Similarity | NPD7115 | Discovery |
0.7019 | Intermediate Similarity | NPD4061 | Clinical (unspecified phase) |
0.7011 | Intermediate Similarity | NPD6925 | Approved |
0.7011 | Intermediate Similarity | NPD5776 | Phase 2 |
0.701 | Intermediate Similarity | NPD5695 | Phase 3 |
0.7 | Intermediate Similarity | NPD3667 | Approved |
0.7 | Intermediate Similarity | NPD5344 | Discontinued |
0.6989 | Remote Similarity | NPD7750 | Discontinued |
0.6989 | Remote Similarity | NPD7524 | Approved |
0.6979 | Remote Similarity | NPD6399 | Phase 3 |
0.6977 | Remote Similarity | NPD7339 | Approved |
0.6977 | Remote Similarity | NPD6942 | Approved |
0.6972 | Remote Similarity | NPD7328 | Approved |
0.6972 | Remote Similarity | NPD7327 | Approved |
0.697 | Remote Similarity | NPD5696 | Approved |
0.6966 | Remote Similarity | NPD7514 | Phase 3 |
0.6966 | Remote Similarity | NPD7332 | Phase 2 |
0.6947 | Remote Similarity | NPD5785 | Approved |
0.6932 | Remote Similarity | NPD7322 | Clinical (unspecified phase) |
0.6932 | Remote Similarity | NPD7145 | Approved |
0.6915 | Remote Similarity | NPD5737 | Approved |
0.6915 | Remote Similarity | NPD6672 | Approved |
0.6909 | Remote Similarity | NPD7516 | Approved |
0.6897 | Remote Similarity | NPD6933 | Approved |
0.6893 | Remote Similarity | NPD7128 | Approved |
0.6893 | Remote Similarity | NPD5739 | Approved |
0.6893 | Remote Similarity | NPD6675 | Approved |
0.6893 | Remote Similarity | NPD6402 | Approved |
0.6889 | Remote Similarity | NPD6902 | Approved |
0.6882 | Remote Similarity | NPD5279 | Phase 3 |
0.6882 | Remote Similarity | NPD4623 | Approved |
0.6882 | Remote Similarity | NPD4519 | Discontinued |
0.6875 | Remote Similarity | NPD5693 | Phase 1 |
0.6869 | Remote Similarity | NPD7902 | Approved |
0.6854 | Remote Similarity | NPD4195 | Approved |
0.6848 | Remote Similarity | NPD4786 | Approved |
0.6847 | Remote Similarity | NPD8294 | Approved |
0.6847 | Remote Similarity | NPD8377 | Approved |
0.6842 | Remote Similarity | NPD4753 | Phase 2 |
0.6842 | Remote Similarity | NPD5328 | Approved |
0.6837 | Remote Similarity | NPD1698 | Clinical (unspecified phase) |
0.6827 | Remote Similarity | NPD5701 | Approved |
0.6827 | Remote Similarity | NPD5697 | Approved |
0.6809 | Remote Similarity | NPD4751 | Clinical (unspecified phase) |
0.6804 | Remote Similarity | NPD5778 | Approved |
0.6804 | Remote Similarity | NPD5779 | Approved |
0.6792 | Remote Similarity | NPD5955 | Clinical (unspecified phase) |
0.6786 | Remote Similarity | NPD8380 | Approved |
0.6786 | Remote Similarity | NPD8296 | Approved |
0.6786 | Remote Similarity | NPD8379 | Approved |
0.6786 | Remote Similarity | NPD8378 | Approved |
0.6786 | Remote Similarity | NPD8335 | Approved |
0.6786 | Remote Similarity | NPD6923 | Approved |
0.6786 | Remote Similarity | NPD8033 | Approved |
0.6786 | Remote Similarity | NPD6922 | Approved |
0.6782 | Remote Similarity | NPD8264 | Approved |
0.6778 | Remote Similarity | NPD5790 | Clinical (unspecified phase) |
0.6778 | Remote Similarity | NPD7525 | Registered |
0.6774 | Remote Similarity | NPD6893 | Approved |
0.6774 | Remote Similarity | NPD6082 | Clinical (unspecified phase) |
0.6771 | Remote Similarity | NPD6698 | Approved |
0.6771 | Remote Similarity | NPD7838 | Discovery |
0.6771 | Remote Similarity | NPD46 | Approved |
0.6762 | Remote Similarity | NPD7320 | Approved |
0.6762 | Remote Similarity | NPD6881 | Approved |
0.6762 | Remote Similarity | NPD6899 | Approved |
0.6742 | Remote Similarity | NPD5784 | Clinical (unspecified phase) |
0.6739 | Remote Similarity | NPD7154 | Phase 3 |
0.6733 | Remote Similarity | NPD6648 | Approved |
0.6706 | Remote Similarity | NPD7144 | Approved |
0.6706 | Remote Similarity | NPD7143 | Approved |
0.6703 | Remote Similarity | NPD6898 | Phase 1 |
0.6701 | Remote Similarity | NPD7087 | Discontinued |
0.6701 | Remote Similarity | NPD6411 | Approved |
0.6701 | Remote Similarity | NPD6079 | Approved |
0.6698 | Remote Similarity | NPD6013 | Approved |
0.6698 | Remote Similarity | NPD6014 | Approved |
0.6698 | Remote Similarity | NPD6373 | Approved |
0.6698 | Remote Similarity | NPD6372 | Approved |
0.6698 | Remote Similarity | NPD6012 | Approved |
0.6637 | Remote Similarity | NPD7503 | Approved |
0.6636 | Remote Similarity | NPD6883 | Approved |
0.6636 | Remote Similarity | NPD7102 | Approved |
0.6636 | Remote Similarity | NPD7290 | Approved |
0.6633 | Remote Similarity | NPD4202 | Approved |
0.663 | Remote Similarity | NPD5209 | Approved |
0.663 | Remote Similarity | NPD4223 | Phase 3 |
0.663 | Remote Similarity | NPD4221 | Approved |
0.6629 | Remote Similarity | NPD6932 | Approved |
0.6628 | Remote Similarity | NPD7152 | Approved |
0.6628 | Remote Similarity | NPD7151 | Approved |
0.6628 | Remote Similarity | NPD7150 | Approved |
0.6604 | Remote Similarity | NPD6011 | Approved |
0.6602 | Remote Similarity | NPD5211 | Phase 2 |
0.6596 | Remote Similarity | NPD7520 | Clinical (unspecified phase) |
0.6593 | Remote Similarity | NPD7509 | Discontinued |
0.6593 | Remote Similarity | NPD4822 | Approved |
0.6593 | Remote Similarity | NPD4819 | Approved |
0.6593 | Remote Similarity | NPD4821 | Approved |
0.6593 | Remote Similarity | NPD4695 | Discontinued |
0.6593 | Remote Similarity | NPD4820 | Approved |
0.6591 | Remote Similarity | NPD8039 | Approved |
0.6585 | Remote Similarity | NPD5325 | Clinical (unspecified phase) |
0.6574 | Remote Similarity | NPD6869 | Approved |
0.6574 | Remote Similarity | NPD6847 | Approved |
0.6574 | Remote Similarity | NPD6649 | Approved |
0.6574 | Remote Similarity | NPD8130 | Phase 1 |
0.6574 | Remote Similarity | NPD6650 | Approved |
0.6574 | Remote Similarity | NPD6617 | Approved |
0.6566 | Remote Similarity | NPD7900 | Approved |
0.6566 | Remote Similarity | NPD7901 | Clinical (unspecified phase) |
0.6562 | Remote Similarity | NPD5208 | Approved |
0.6559 | Remote Similarity | NPD5362 | Discontinued |
0.6556 | Remote Similarity | NPD4271 | Approved |
0.6556 | Remote Similarity | NPD4268 | Approved |
0.6552 | Remote Similarity | NPD7507 | Approved |
0.6543 | Remote Similarity | NPD4192 | Approved |
0.6543 | Remote Similarity | NPD4191 | Approved |
0.6543 | Remote Similarity | NPD4193 | Approved |
0.6543 | Remote Similarity | NPD4194 | Approved |
0.6535 | Remote Similarity | NPD4755 | Approved |
0.6514 | Remote Similarity | NPD6882 | Approved |
0.6514 | Remote Similarity | NPD6053 | Discontinued |
0.6514 | Remote Similarity | NPD8297 | Approved |
0.6509 | Remote Similarity | NPD5954 | Clinical (unspecified phase) |
0.6509 | Remote Similarity | NPD6412 | Phase 2 |
0.65 | Remote Similarity | NPD5210 | Approved |
0.65 | Remote Similarity | NPD4629 | Approved |
0.6495 | Remote Similarity | NPD6101 | Approved |
0.6495 | Remote Similarity | NPD6080 | Approved |
0.6495 | Remote Similarity | NPD5764 | Clinical (unspecified phase) |
0.6495 | Remote Similarity | NPD6673 | Approved |
0.6495 | Remote Similarity | NPD6904 | Approved |
0.6489 | Remote Similarity | NPD4197 | Approved |
0.6484 | Remote Similarity | NPD6683 | Phase 2 |
0.6481 | Remote Similarity | NPD6371 | Approved |
0.6476 | Remote Similarity | NPD5141 | Approved |
0.6471 | Remote Similarity | NPD8029 | Clinical (unspecified phase) |
0.6458 | Remote Similarity | NPD3573 | Approved |
0.6437 | Remote Similarity | NPD4243 | Approved |
0.6436 | Remote Similarity | NPD5222 | Approved |
0.6436 | Remote Similarity | NPD5221 | Approved |
0.6436 | Remote Similarity | NPD5220 | Clinical (unspecified phase) |
0.6436 | Remote Similarity | NPD4697 | Phase 3 |
0.6436 | Remote Similarity | NPD4792 | Clinical (unspecified phase) |
0.6422 | Remote Similarity | NPD6401 | Clinical (unspecified phase) |
0.6421 | Remote Similarity | NPD5329 | Approved |
0.6421 | Remote Similarity | NPD5363 | Approved |
0.6408 | Remote Similarity | NPD5286 | Approved |
0.6408 | Remote Similarity | NPD4700 | Approved |
0.6408 | Remote Similarity | NPD4696 | Approved |
0.6408 | Remote Similarity | NPD5285 | Approved |
0.6387 | Remote Similarity | NPD7319 | Approved |
0.6383 | Remote Similarity | NPD5331 | Approved |
0.6383 | Remote Similarity | NPD5332 | Approved |
0.6374 | Remote Similarity | NPD3617 | Approved |
0.6373 | Remote Similarity | NPD5173 | Approved |
0.6364 | Remote Similarity | NPD8034 | Phase 2 |
0.6364 | Remote Similarity | NPD8035 | Phase 2 |
0.6364 | Remote Similarity | NPD5284 | Approved |
0.6364 | Remote Similarity | NPD5281 | Approved |
0.6354 | Remote Similarity | NPD4689 | Approved |
0.6354 | Remote Similarity | NPD4693 | Phase 3 |
PubChem CID   | |
ChEMBL   | CHEMBL3586268 |
ZINC   |
Molecular Weight:   | 318.22 |
ALogP:   | 1.4222 |
MLogP:   | 3.33 |
XLogP:   | 5.571 |
# Rotatable Bonds:   | 7 |
Polar Surface Area:   | 46.53 |
# H-Bond Aceptor:   | 3 |
# H-Bond Donor:   | 1 |
# Rings:   | 3 |
# Heavy Atoms:   | 23 |