TCM-ID Component

Description of the Component

Component ID	TCMH2333
Latin Name	Cynanchum paniculatum
English Name	Paniculate swallowwort
Chinese Pinyin Name	Xu Chang Qing
中文名	å¾é•¿å¿
TCM Properties	Warm,Pungent
TCM Meridians	Lung,Stomach,Liver,Kidney
Therapeutic Class English	For dispelling wind-dampness
Therapeutic Class Chinese	ç¥›é£Žæ¹¿
Functions	relieve rheumatic conditions, and arrest pain and itching
Toxicity	NA
Geo-authentic habitats (道地产区)	Jiangsu Province,Shanghai
Reference	Chinese Pharmacopoeia (2015)
Barcode ID
Barcode Source

TCM Prescriptions with the Component

Prescription ID	Prescription English Name	Prescription Chinese Name
TCMFx3828	Bo Gu Decoction	é©³éª¨æ°´
TCMFx2320	Dermatitis Adhesive Plaster	çš®ç‚Žçµç¡¬è†
TCMFx3341	Die Da Bang Yao Wine	è·Œæ‰“æ¦œè¯é…’
TCMFx3395	Die Da Shang Ke Wine	è·Œæ‰“ä¼¤ç§‘é…’
TCMFx3418	Die Da Wan Hua You	è·Œæ‰“ä¸‡èŠ±æ²¹
TCMFx3351	Feng Shi Ding Capsules	é£Žæ¹¿å®šèƒ¶å›Š
TCMFx410	Feng Shi Ding Tablet	é£Žæ¹¿å®šç‰‡
TCMFx3357	Feng Shi Ding Tablets	é£Žæ¹¿å®šç‰‡
TCMFx6942	Fu Fang Nan Xing Zhi Tong Ointment	å¤æ–¹å—æ˜Ÿæ¢ç—›è†
TCMFx3333	Fu Fang Yuan Hu Zhi Tong Tablets	å¤æ–¹å…ƒèƒ¡æ¢ç—›ç‰‡
TCMF3109	Fu Yue Kang Capsules	å¦‡æœˆåº·èƒ¶å›Š
TCMFx3417	Gu Ci Pills	éª¨åˆºä¸¸
TCMFx3425	Gu Ci Xiao Tong Capsules	éª¨åˆºæ¶ˆç—›èƒ¶å›Š
TCMFx748	Gu Ci Xiao Tong Tablet	éª¨åˆºæ¶ˆç—›ç‰‡
TCMFx3433	Gu Ci Xiao Tong Tablets	éª¨åˆºæ¶ˆç—›ç‰‡
TCMFx4936	Jian Er Gan Ji Powder	å¥å„¿ç–³ç§¯æ•£
TCMF4308	Jin Gu Zhi Tong Ointment	ç‹éª¨æ¢ç—›è†
TCMFx6976	Jing Dai Ning Capsules	ç»å¸¦å®èƒ¶å›Š
TCMFx4186	Liang Cai Xin Die Da Pills	æ¢è´¢ä¿¡è·Œæ‰“ä¸¸
TCMF2116	Lithagogue Infusion	æŽ’çŸ³å†²å‰‚
TCMFx4862	Luo Fu Shan Bai Cao You	ç½—æµ®å±±ç™¾è‰æ²¹
TCMFx4869	Luo Fu Shan Feng Shi Gao Yao	ç½—æµ®å±±é£Žæ¹¿è†è¯
TCMF4472	Min Dong Jian Qu	é—½ä¸œå»ºæ›²
TCMFx4435	Pai Shi Granules	æŽ’çŸ³é¢—ç²’
TCMFx4427	Pai Shi Ointment	æŽ’çŸ³è†
TCMFx1000	PaiÂ ShiÂ Granules	æŽ’çŸ³é¢—ç²’
TCMFx5474	Shan Long Yao Wine	å±±é¾™è¯é…’
TCMFx5761	Shang Tong Ding	ä¼¤ç—›é…Š
TCMFx5162	She Xiang Jie Tong Ointment	éºé¦™è§£ç—›è†
TCMFx5358	Shen Nong Yao Wine	ç¥žå†œè¯é…’
TCMFx5726	Shuang Xiang Pai Shi Granules	åŒé¦™æŽ’çŸ³é¢—ç²’
TCMF2002	Stomach Strengthening Tea	å¥èƒƒèŒ¶
TCMFx5978	Xiang Gui Huo Xue Ointment	é¦™æ¡‚æ´»è¡€è†
TCMFx6496	Xiao Zhong Zhi Tong Ding	æ¶ˆè‚¿æ¢ç—›é…Š
TCMFx1021	Xiao Zhong Zhi Tong Tincture	æ¶ˆè‚¿æ¢ç—›é…Š
TCMFx6336	Xuan Ling Yao Decoction	ç™£çµè¯æ°´
TCMFx108	Xuan Ning Liniment	ç™£å®æ½å‰‚
TCMF835	Yang Zheng Xiao Ji Capsule	å…»æ£æ¶ˆç§¯èƒ¶å›Š
TCMFx6210	Zhen Zhu Wei An Pills	çç èƒƒå®‰ä¸¸
TCMFx727	Zhen Zhu Wei An Pills	çç èƒƒå®‰ä¸¸
TCMFx397	Zheng Gu Shui	æ£éª¨æ°´

Targeted Human Proteins by the Ingredient of Component

Target ID	Gene Symbol	Target Name	Target Class	Uniprot ID
TCMT232	ABCB1	P-glycoprotein 1	Transporter	P08183
TCMT33	CYP3A4	Cytochrome P450 3A4	Oxidoreductase	P08684
TCMT80	MAPK1	MAP kinase ERK2	Kinase	P28482

Targeted Pathogenic Microbes by the Ingredient of Component

Target ID	Target Name
TCMT1218	Staphylococcus aureus

Ingredient Structrues

Ingredient ID: TCMC615
Formula: C10H12O4

Common Name	Acetosyringone
IUPAC Name	1-(4-hydroxy-3,5-dimethoxyphenyl)ethanone
Canonical SMILES	COc1cc(cc(c1O)OC)C(=O)C
Standard InCHI	InChI=1S/C10H12O4/c1-6(11)7-4-8(13-2)10(12)9(5-7)14-3/h4-5,12H,1-3H3
Standard InCHIKey	OJOBTAOGJIWAGB-UHFFFAOYSA-N
External Identifiers	ChEMBL [CHEMBL224146]; PubChem [17198];
Reference of Component-Ingredient Pair	N/A

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH924	Zanthoxylum bungeanum	Hua Jiao	èŠ±æ¤’
TCMH2333	Cynanchum paniculatum	Xu Chang Qing	å¾é•¿å¿
TCMH2671	Polyporus umbellatus	Zhu Ling	çŒªè‹“

Ingredient ID: TCMC5929
Formula: C21H32O5

Common Name	Lineolone
IUPAC Name	1-[(3S,8S,9R,10R,12R,13S,14R,17R)-3,8,12,14-tetrahydroxy-10,13-dimethyl-2,3,4,7,9,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-17-yl]ethanone
Canonical SMILES	O[C@H]1CC[C@]2(C(=CC[C@@]3([C@@H]2C[C@@H](O)[C@]2([C@]3(O)CC[C@H]2C(=O)C)C)O)C1)C
Standard InCHI	InChI=1S/C21H32O5/c1-12(22)15-6-9-21(26)19(15,3)17(24)11-16-18(2)7-5-14(23)10-13(18)4-8-20(16,21)25/h4,14-17,23-26H,5-11H2,1-3H3/t14-,15-,16+,17+,18-,19-,20-,21+/m0/s1
Standard InCHIKey	YETBVMVJLDSXHU-OTKHHKLUSA-N
External Identifiers	ChEMBL [N/A]; PubChem [12311278];
Reference of Component-Ingredient Pair	10923833

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH2333	Cynanchum paniculatum	Xu Chang Qing	å¾é•¿å¿

Ingredient ID: TCMC3351
Formula: C9H10O3

Common Name	Isopaeonol
IUPAC Name	1-(3-hydroxy-4-methoxyphenyl)ethanone
Canonical SMILES	COc1ccc(cc1O)C(=O)C
Standard InCHI	InChI=1S/C9H10O3/c1-6(10)7-3-4-9(12-2)8(11)5-7/h3-5,11H,1-2H3
Standard InCHIKey	YLTGFGDODHXMFB-UHFFFAOYSA-N
External Identifiers	ChEMBL [N/A]; PubChem [95693];
Reference of Component-Ingredient Pair	14630187

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH2333	Cynanchum paniculatum	Xu Chang Qing	å¾é•¿å¿

Ingredient ID: TCMC2784
Formula: C28H40O9

Common Name	Paniculatumoside B
IUPAC Name	n.a.
Canonical SMILES	CO[C@@H]1C[C@H](O[C@H]2CC[C@]3(C(=CC[C@@H]4[C@@H]3C/C=C3/[C@H](O)O[C@@]5([C@H]3[C@@H](OC4=O)CO5)C)C2)C)O[C@@H]([C@H]1O)C
Standard InCHI	InChI=1S/C28H40O9/c1-14-24(29)20(32-4)12-22(34-14)35-16-9-10-27(2)15(11-16)5-6-17-19(27)8-7-18-23-21(36-25(17)30)13-33-28(23,3)37-26(18)31/h5,7,14,16-17,19-24,26,29,31H,6,8-13H2,1-4H3/b18-7+/t14-,16+,17-,19+,20-,21+,22+,23-,24-,26-,27+,28-/m1/s1
Standard InCHIKey	RIZURMSYPNFAAV-QBJYZOITSA-N
External Identifiers	ChEMBL [CHEMBL509742]; PubChem [44575541];
Reference of Component-Ingredient Pair	N/A

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH2333	Cynanchum paniculatum	Xu Chang Qing	å¾é•¿å¿

Ingredient ID: TCMC2755
Formula: C28H40O9

Common Name	Paniculatumoside A
IUPAC Name	n.a.
Canonical SMILES	CO[C@@H]1C[C@H](O[C@H]2CC[C@]3(C(=CC[C@@H]4[C@@H]3C/C=C3/[C@@H](O)O[C@@]5([C@H]3[C@H](OC4=O)CO5)C)C2)C)O[C@@H]([C@H]1O)C
Standard InCHI	InChI=1S/C28H40O9/c1-14-24(29)20(32-4)12-22(34-14)35-16-9-10-27(2)15(11-16)5-6-17-19(27)8-7-18-23-21(36-25(17)30)13-33-28(23,3)37-26(18)31/h5,7,14,16-17,19-24,26,29,31H,6,8-13H2,1-4H3/b18-7+/t14-,16+,17-,19+,20-,21-,22+,23-,24-,26+,27+,28-/m1/s1
Standard InCHIKey	RIZURMSYPNFAAV-GSCZNSFOSA-N
External Identifiers	ChEMBL [CHEMBL467256]; PubChem [21599990];
Reference of Component-Ingredient Pair	N/A

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH2333	Cynanchum paniculatum	Xu Chang Qing	å¾é•¿å¿

Ingredient ID: TCMC2
Formula: C23H25NO3

Common Name	(-)-Antofine
IUPAC Name	(13aR)-2,3,6-trimethoxy-9,11,12,13,13a,14-hexahydrophenanthro[9,10-f]indolizine
Canonical SMILES	COc1ccc2c(c1)c1cc(OC)c(cc1c1c2CN2CCC[C@@H]2C1)OC
Standard InCHI	InChI=1S/C23H25NO3/c1-25-15-6-7-16-18(10-15)20-12-23(27-3)22(26-2)11-19(20)17-9-14-5-4-8-24(14)13-21(16)17/h6-7,10-12,14H,4-5,8-9,13H2,1-3H3/t14-/m1/s1
Standard InCHIKey	NCVWJDISIZHFQS-CQSZACIVSA-N
External Identifiers	ChEMBL [CHEMBL228286]; PubChem [639288];
Reference of Component-Ingredient Pair	28666888

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH2333	Cynanchum paniculatum	Xu Chang Qing	å¾é•¿å¿

Ingredient ID: TCMC1826
Formula: C9H10O3

Common Name	Paeonol
IUPAC Name	1-(2-hydroxy-4-methoxyphenyl)ethanone
Canonical SMILES	COc1ccc(c(c1)O)C(=O)C
Standard InCHI	InChI=1S/C9H10O3/c1-6(10)8-4-3-7(12-2)5-9(8)11/h3-5,11H,1-2H3
Standard InCHIKey	UILPJVPSNHJFIK-UHFFFAOYSA-N
External Identifiers	ChEMBL [CHEMBL1079227]; PubChem [11092];
Reference of Component-Ingredient Pair	21201807

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH1865	Paeonia obovata	Shao Yao	èŠè¯
TCMH810	Paeonia albiflora	Hang Shao	æèŠ
TCMH865	Carthamus tinctorius	Hong Hua	çº¢èŠ±
TCMH1513	Paeonia moutan	Mu Dan Pi	ç‰¡ä¸¹çš®
TCMH1923	Acorus tatarinowii	Shi Chang Pu Qing Gao	çŸ³è–è’²æ¸…è†
TCMH571	Paeonia suffruticosa	Fen Dan Pi	ç²‰ä¸¹çš®
TCMH1409	Cannabis sativa	Ma Ren	éº»ä»
TCMH1469	Flos mume	Mei Hua	æ¢…èŠ±
TCMH1894	Pinellia ternata	Sheng Ban Xia	ç”ŸåŠå¤
TCMH1839	Panax ginseng	Shan Shen	å±±å‚
TCMH1798	Morus alba	Sang Zhi	æ¡‘æž
TCMH447	Illicium difengpi	Di Feng Pi	åœ°æž«çš®
TCMH1531	Akebia quinata	Mu Tong	æœ¨é€š
TCMH114	Platycladus orientalis	Bai Ye	æŸå¶
TCMH130	Pinellia ternata	Ban Xia	åŠå¤
TCMH131	Pinellia ternata	Ban Xia Qu	åŠå¤æ›²
TCMH1677	Pinellia ternata	Qing Ban Xia	æ¸…åŠå¤
TCMH258	Paeonia obovata	Chi Shao	èµ¤èŠ
TCMH1792	Morus alba	Sang Pi	æ¡‘çš®
TCMH1797	Morus alba	Sang Ye	æ¡‘å¶
TCMH1721	Panax ginseng	Ren Shen	äººå‚
TCMH1728	Panax ginseng	Ren Shen Ye	äººå‚å¶
TCMH60	Ginkgo biloba	Bai Guo	ç™½æžœ
TCMH61	Ginkgo biloba	Bai Guo Ren	ç™½æžœä»
TCMH104	Paeonia lactiflora	Bai Shao	ç™½èŠ
TCMH105	Paeonia lactiflora	Bai Shao Gan Jin Gao	ç™½èŠå¹²æµ¸è†
TCMH1005	Cannabis sativa	Huo Ma Ren	ç«éº»ä»
TCMH1920	Acorus tatarinowii	Shi Chang Pu	çŸ³è–è’²
TCMH1922	Acorus tatarinowii	Shi Chang Pu Jin Gao	çŸ³è–è’²æµ¸è†
TCMH2333	Cynanchum paniculatum	Xu Chang Qing	å¾é•¿å¿
TCMH2506	Ginkgo biloba	Yin Xing Ye	é“¶æå¶
TCMH2706	Lithospermum erythrorhizon	Zi Cao	ç´«è‰
TCMH2239	Asarum sieboldii	Xi Xin	ç»†è¾›
TCMH2267	Periploca sepium	Xiang Jia Pi	é¦™åŠ çš®
TCMH2315	Arnebia euchroma	Xin Jiang Zi Cao	æ–°ç–†ç´«è‰

Ingredient ID: TCMC1150
Formula: C8H10

Common Name	Ethylbenzene
IUPAC Name	ethylbenzene
Canonical SMILES	CCc1ccccc1
Standard InCHI	InChI=1S/C8H10/c1-2-8-6-4-3-5-7-8/h3-7H,2H2,1H3
Standard InCHIKey	YNQLUTRBYVCPMQ-UHFFFAOYSA-N
External Identifiers	ChEMBL [CHEMBL371561]; PubChem [7500];
Reference of Component-Ingredient Pair	29217486

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH1063	Curcuma longa	Jiang Huang	å§œé»„
TCMH1923	Acorus tatarinowii	Shi Chang Pu Qing Gao	çŸ³è–è’²æ¸…è†
TCMH1518	Chaenomeles sinensis	Mu Gua	æœ¨ç“œ
TCMH1184	Citrus reticulata	Ju Pi	æ©˜çš®
TCMH1734	Homo sapiens	Ren Zhong Bai	äººä¸ç™½
TCMH309	Curcuma longa	Chuan Yu Jin	å·éƒé‡‘
TCMH1178	Citrus reticulata	Ju He	æ©˜æ ¸
TCMH1920	Acorus tatarinowii	Shi Chang Pu	çŸ³è–è’²
TCMH1922	Acorus tatarinowii	Shi Chang Pu Jin Gao	çŸ³è–è’²æµ¸è†
TCMH2333	Cynanchum paniculatum	Xu Chang Qing	å¾é•¿å¿
TCMH2556	Polygala tenuifolia	Yuan Zhi Liu Jin Gao	è¿œå¿—æµæµ¸è†
TCMH2710	Homo sapiens	Zi He Che	ç´«æ²³è½¦
TCMH2551	Polygonatum odoratum	Yu Zhu	çŽ‰ç«¹
TCMH2554	Polygala tenuifolia	Yuan Zhi	è¿œå¿—
TCMH2555	Polygala tenuifolia	Yuan Zhi Jin Gao	è¿œå¿—æµ¸è†

Properties

Ingredient ID	Formulae	Name	MW	AlogP	MlogP	XlogP	# HBA	# HBD	PSA	# Rotatable Bond	# Ring	# Heacy Atom
TCMC2	C23H25NO3	(-)-Antofine	363.18	-0.683	3.55	3.45	1	0	30.93	6	5	27
TCMC615	C10H12O4	Acetosyringone	196.07	-0.8178	2.12	0.447	1	1	55.76	7	1	14
TCMC1150	C8H10	Ethylbenzene	106.08	0.3069	2.34	4.954	0	0	0	2	1	8
TCMC1826	C9H10O3	Paeonol	166.06	-0.766	2.12	1.32	1	1	46.53	5	1	12
TCMC2755	C28H40O9	Paniculatumoside A	520.27	-1.5282	3.55	1.053	9	2	112.91	9	6	37
TCMC2784	C28H40O9	Paniculatumoside B	520.27	-1.5282	3.55	1.053	9	2	112.91	9	6	37
TCMC3351	C9H10O3	Isopaeonol	166.0629942	-0.766	2.12	0.891	1	1	46.53	2	1	12
TCMC5929	C21H32O5	Lineolone	364.2249741	-1.4621	3.22	0.302	5	4	97.99	1	4	26

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Data Section	Select to Download
1. General Information of the Component
2. TCM Prescriptions with the Component
3. Putative Targets
4. Activity & References for Filtering Putative Targets
5. Ingredient Data & Chemical Structure Information (Properties, InChI, InChIkey, SMILES, etc.)

Component: Cynanchum paniculatum å¾é•¿å¿

Description of the Component

Component ID

Latin Name

English Name

Chinese Pinyin Name

中文名

TCM Properties

TCM Meridians

Therapeutic Class English

Therapeutic Class Chinese

Functions

Toxicity

Geo-authentic habitats (道地产区)

Reference

Barcode ID

Barcode Source

TCM Prescriptions with the Component

Targeted Human Proteins by the Ingredient of Component

Targeted Pathogenic Microbes by the Ingredient of Component

Ingredient Structrues

Ingredient ID: TCMC615

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC5929

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC3351

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC2784

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC2755

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC2

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC1826

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC1150

Occurrence of the ingredient across TCM components

Properties

Download Data

Component: Cynanchum paniculatum å¾é•¿å¿