TCM-ID Component

Description of the Component

Component ID	TCMH185
Latin Name	Phyllanthus niruri
English Name	Gale of the wind
Chinese Pinyin Name	Bing Tang Cao
中文名	冰糖草
TCM Properties
TCM Meridians
Therapeutic Class English
Therapeutic Class Chinese
Functions
Toxicity	NA
Geo-authentic habitats (道地产区)	NA
Reference	CFDA
Barcode ID	GENG816-14, GBVH3468-11
Barcode Source	BOLDSYSTEMS

TCM Prescriptions with the Component

Prescription ID	Prescription English Name	Prescription Chinese Name
TCMFx5653	Tiao Jing Yi Mu Tablets	调经益母片

Targeted Human Proteins by the Ingredient of Component

Target ID	Gene Symbol	Target Name	Target Class	Uniprot ID
TCMT223	AKR1B1	Aldose reductase	Oxidoreductase	P15121
TCMT605	EDNRA	Endothelin receptor ET-A	GPCR	P25101

Targeted Pathogenic Microbes by the Ingredient of Component

Target ID	Target Name
TCMT1294	Human parainfluenza virus 3
TCMT1438	Plasmodium falciparum
TCMT1447	Respiratory syncytial virus

Ingredient Structrues

Ingredient ID: TCMC795
Formula: C13H16O10

Common Name	Beta-Glucogallin
IUPAC Name	[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] 3,4,5-trihydroxybenzoate
Canonical SMILES	OC[C@H]1O[C@@H](OC(=O)c2cc(O)c(c(c2)O)O)[C@@H]([C@H]([C@@H]1O)O)O
Standard InCHI	InChI=1S/C13H16O10/c14-3-7-9(18)10(19)11(20)13(22-7)23-12(21)4-1-5(15)8(17)6(16)2-4/h1-2,7,9-11,13-20H,3H2/t7-,9-,10+,11-,13+/m1/s1
Standard InCHIKey	GDVRUDXLQBVIKP-HQHREHCSSA-N
External Identifiers	ChEMBL [CHEMBL480283]; PubChem [124021];
Reference of Component-Ingredient Pair	19526787

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH1862	Cornus officinalis	Shan Zhu Yu	山茱萸
TCMH1682	Artemisia carvifolia	Qing Hao Zi	青蒿子
TCMH2087	Grangea maderaspatana	Tian Ji Huang	田基黄
TCMH366	Rheum officinale	Da Huang Liu Jin Gao	大黄流浸膏
TCMH500	Benincasa hispida	Dong Gua Zi	冬瓜子
TCMH1525	Crassostrea gigas	Mu Li	牡蛎
TCMH185	Phyllanthus niruri	Bing Tang Cao	冰糖草
TCMH2135	Glycyrrhiza uralensis	Tu Gan Cao	土甘草
TCMH1965	Rheum palmatum	Shu Da Huang	熟大黄
TCMH1175	Cornus officinalis	Jiu Yu Rou	酒萸肉
TCMH498	Benincasa hispida	Dong Gua Pi	冬瓜皮
TCMH363	Rheum officinale	Da Huang	大黄
TCMH365	Rheum officinale	Da Huang Jin Gao	大黄浸膏
TCMH1681	Artemisia carvifolia	Qing Hao	青蒿
TCMH628	Glycyrrhiza uralensis	Gan Cao	甘草
TCMH629	Glycyrrhiza uralensis	Gan Cao Fen	甘草粉
TCMH630	Glycyrrhiza uralensis	Gan Cao Gan Gao	甘草干膏
TCMH631	Glycyrrhiza uralensis	Gan Cao Gan Gao Fen	甘草干膏粉
TCMH632	Glycyrrhiza uralensis	Gan Cao Gan Jin Gao	甘草干浸膏
TCMH633	Glycyrrhiza uralensis	Gan Cao Gao	甘草膏
TCMH634	Glycyrrhiza uralensis	Gan Cao Jie	甘草节
TCMH635	Glycyrrhiza uralensis	Gan Cao Jin Gao	甘草浸膏
TCMH636	Glycyrrhiza uralensis	Gan Cao Liu Jin Gao	甘草流浸膏
TCMH1475	Glycyrrhiza uralensis	Mi Gan Cao	蜜甘草
TCMH1899	Glycyrrhiza uralensis	Sheng Gan Cao	生甘草

Ingredient ID: TCMC2778
Formula: C27H22O18

Common Name	1-O-Galloyl-6-O-Luteoyl-Alpha-D-Glucose
IUPAC Name	[(2R,3S,4S,5R,6R)-3,4,5-trihydroxy-6-(3,4,5-trihydroxybenzoyl)oxyoxan-2-yl]methyl 3,4,8,9,10-pentahydroxy-6-oxobenzo[c]chromene-1-carboxylate
Canonical SMILES	O[C@H]1[C@H](O)[C@@H](COC(=O)c2cc(O)c(c3c2c2c(O)c(O)c(cc2c(=O)o3)O)O)O[C@@H]([C@@H]1O)OC(=O)c1cc(O)c(c(c1)O)O
Standard InCHI	InChI=1S/C27H22O18/c28-9-1-6(2-10(29)16(9)32)24(39)45-27-22(38)21(37)19(35)13(43-27)5-42-25(40)8-4-12(31)18(34)23-15(8)14-7(26(41)44-23)3-11(30)17(33)20(14)36/h1-4,13,19,21-22,27-38H,5H2/t13-,19-,21+,22-,27-/m1/s1
Standard InCHIKey	WXECVBMGZXQIIU-KFJNVFKXSA-N
External Identifiers	ChEMBL [CHEMBL447617]; PubChem [11296628];
Reference of Component-Ingredient Pair	N/A

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH185	Phyllanthus niruri	Bing Tang Cao	冰糖草

Ingredient ID: TCMC2614
Formula: C26H28O16

Common Name	Quercetin 3-O-Sambubioside
IUPAC Name	3-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxyoxan-2-yl]oxy-2-(3,4-dihydroxyphenyl)-5,7-dihydroxychromen-4-one
Canonical SMILES	OC[C@H]1O[C@@H](Oc2c(oc3c(c2=O)c(O)cc(c3)O)c2ccc(c(c2)O)O)[C@@H]([C@H]([C@@H]1O)O)O[C@@H]1OC[C@H]([C@@H]([C@H]1O)O)O
Standard InCHI	InChI=1S/C26H28O16/c27-6-15-18(34)20(36)24(42-25-21(37)17(33)13(32)7-38-25)26(40-15)41-23-19(35)16-12(31)4-9(28)5-14(16)39-22(23)8-1-2-10(29)11(30)3-8/h1-5,13,15,17-18,20-21,24-34,36-37H,6-7H2/t13-,15-,17+,18-,20+,21-,24-,25+,26+/m1/s1
Standard InCHIKey	NKFZLEYLWAFYEH-CJNLAGEVSA-N
External Identifiers	ChEMBL [CHEMBL455758]; PubChem [5487635];
Reference of Component-Ingredient Pair	N/A

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH2352	Saussurea involucrata	Xue Lian Hua	雪莲花
TCMH2081	Actinidia arguta	Teng Li Gen	藤梨根
TCMH526	Eucommia ulmoides	Du Zhong Ye	杜仲叶
TCMH1615	Eriobotrya japonica	Pi Ba Ren	枇杷仁
TCMH185	Phyllanthus niruri	Bing Tang Cao	冰糖草
TCMH524	Eucommia ulmoides	Du Zhong	杜仲
TCMH525	Eucommia ulmoides	Du Zhong Tan	杜仲炭
TCMH2098	Saussurea involucrata	Tian Shan Xue Lian Hua	天山雪莲花
TCMH2351	Saussurea involucrata	Xue Lian	雪莲

Ingredient ID: TCMC1571
Formula: C14H10O8

Common Name	Methylbrevifolin Carboxylate
IUPAC Name	methyl 7,8,9-trihydroxy-3,5-dioxo-1,2-dihydrocyclopenta[c]isochromene-1-carboxylate
Canonical SMILES	COC(=O)C1CC(=O)c2c1c1c(O)c(O)c(cc1c(=O)o2)O
Standard InCHI	InChI=1S/C14H10O8/c1-21-13(19)5-3-7(16)12-9(5)8-4(14(20)22-12)2-6(15)10(17)11(8)18/h2,5,15,17-18H,3H2,1H3
Standard InCHIKey	JNWDNAASYHRXMG-UHFFFAOYSA-N
External Identifiers	ChEMBL [CHEMBL567076]; PubChem [5319518];
Reference of Component-Ingredient Pair	N/A

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH457	Euphorbia humifusa	Di Mian Cao	地绵草
TCMH2607	Phyllanthus urinaria	Zhen Zhu Cao	珍珠草
TCMH185	Phyllanthus niruri	Bing Tang Cao	冰糖草
TCMH1247	Geranium wilfordii	Lao Guan Cao	老鹳草
TCMH2465	Phyllanthus urinaria	Ye Xia Zhu	叶下珠
TCMH454	Euphorbia humifusa	Di Jin Cao	地锦草

Properties

Ingredient ID	Formulae	Name	MW	AlogP	MlogP	XlogP	# HBA	# HBD	PSA	# Rotatable Bond	# Ring	# Heacy Atom	Lipinski RO5 Violation
TCMC795	C13H16O10	Beta-Glucogallin	332.07	-3.5251	1.79	-1.304	7	7	177.14	11	2	23	1
TCMC1571	C14H10O8	Methylbrevifolin Carboxylate	306.04	-2.0091	2.12	-0.92	5	3	130.36	6	3	22	0
TCMC2614	C26H28O16	Quercetin 3-O-Sambubioside	596.14	-6.1283	2.56	-1.648	11	10	265.52	16	5	42	2
TCMC2778	C27H22O18	1-O-Galloyl-6-O-Luteoyl-Alpha-D-Glucose	634.08	-5.5485	2.45	-1.35	9	11	310.66	18	5	45	1

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Data Section	Select to Download
1. General Information of the Component
2. TCM Prescriptions with the Component
3. Putative Targets
4. Activity & References for Filtering Putative Targets
5. Ingredient Data & Chemical Structure Information (Properties, InChI, InChIkey, SMILES, etc.)

Component: Phyllanthus niruri 冰糖草

Description of the Component

Component ID

Latin Name

English Name

Chinese Pinyin Name

中文名

TCM Properties

TCM Meridians

Therapeutic Class English

Therapeutic Class Chinese

Functions

Toxicity

Geo-authentic habitats (道地产区)

Reference

Barcode ID

Barcode Source

TCM Prescriptions with the Component

Targeted Human Proteins by the Ingredient of Component

Targeted Pathogenic Microbes by the Ingredient of Component

Ingredient Structrues

Ingredient ID: TCMC795

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC2778

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC2614

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC1571

Occurrence of the ingredient across TCM components

Properties

Download Data