Description of the Component
Component ID |
TCMH1514 |
Latin Name |
Fructus caryophylli |
English Name |
Clove fruit |
Chinese Pinyin Name |
Mu Ding Xiang |
中文名 |
母丁香 |
TCM Properties |
Warm,Pungent |
TCM Meridians |
Spleen,Stomach,Kidney |
Therapeutic Class English |
For warming interior |
Therapeutic Class Chinese |
温里 |
Functions |
warm the spleen and stomach, regulate the adverse flow of the stomach qi, and restore the kidney yang |
Toxicity |
NA |
Geo-authentic habitats (道地产区) |
NA |
Reference |
Chinese Pharmacopoeia (2015) |
Barcode ID |
|
Barcode Source |
TCM Prescriptions with the Component
| Prescription ID | Prescription English Name | Prescription Chinese Name |
|---|---|---|
| TCMFx2990 | Bai Hua She Ointment | 白花蛇膏 |
| TCMF3087 | Er Yi Pills | 二益丸 |
| TCMFx3644 | Fo Shan Ren Shen Zai Zao Pills | 佛山人参再造丸 |
| TCMFx3635 | Fo Shan Ren Shen Zai Zao Tablets | 佛山人参再造片 |
| TCMFx4114 | Hai Ma Bu Shen Pills | 海马补肾丸 |
| TCMFx4121 | Hai Ma Duo Bian Pills | 海马多鞭丸 |
| TCMFx4129 | Hai Ma San Shen Pills | 海马三肾丸 |
| TCMFx4264 | Hui Sheng Zai Zao Pills | 回生再造丸 |
| TCMFx4274 | Hui Tian Zai Zao Pills | 回天再造丸 |
| TCMFx55 | Nuan Qi Ointment | 暖脐膏 |
| TCMFx4364 | Nuan Qi Ointment | 暖脐膏 |
| TCMFx2508 | Nuanqi Plaster | 暖脐膏 |
| TCMFx5537 | Ren Shen Zai Zao Pills | 人参再造丸 |
| TCMFx3551 | Shen Rong Gu Ben Huan Shao Pills | 参茸固本还少丸 |
| TCMF5032 | Shi Xiang Ding Tong Pills | 十香定痛丸 |
| TCMFx5040 | Shi Xiang Nuan Qi Ointment | 十香暖脐膏 |
| TCMFx470 | Zai Zao Pills | 再造丸 |
Targeted Human Proteins by the Ingredient of Component
| Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
|---|---|---|---|---|
| TCMT1 | EHMT2 | Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 | Transferase | Q96KQ7 |
| TCMT13 | APEX1 | DNA-(apurinic or apyrimidinic site) lyase | Lyase | P27695 |
| TCMT133 | CA1 | Carbonic anhydrase I | Lyase | P00915 |
| TCMT134 | CA2 | Carbonic anhydrase II | Lyase | P00918 |
| TCMT135 | CA14 | Carbonic anhydrase XIV | Lyase | Q9ULX7 |
| TCMT136 | CA12 | Carbonic anhydrase XII | Lyase | O43570 |
| TCMT137 | CA9 | Carbonic anhydrase IX | Lyase | Q16790 |
| TCMT138 | CA7 | Carbonic anhydrase VII | Lyase | P43166 |
| TCMT139 | CA6 | Carbonic anhydrase VI | Lyase | P23280 |
| TCMT140 | CA5B | Carbonic anhydrase VB | Lyase | Q9Y2D0 |
| TCMT141 | CA5A | Carbonic anhydrase VA | Lyase | P35218 |
| TCMT142 | CA4 | Carbonic anhydrase IV | Lyase | P22748 |
| TCMT143 | CA3 | Carbonic anhydrase III | Lyase | P07451 |
| TCMT158 | EPHX2 | Epoxide hydratase | Lyase | P34913 |
| TCMT162 | UGT1A1 | UDP-glucuronosyltransferase 1-1 | Transferase | P22309 |
| TCMT17 | POLB | DNA polymerase beta | Transferase | P06746 |
| TCMT18 | GAA | Lysosomal alpha-glucosidase | Hydrolase | P10253 |
| TCMT187 | AR | Androgen Receptor | Nuclear receptor | P10275 |
| TCMT189 | DUSP3 | Dual specificity protein phosphatase 3 | Hydrolase | P51452 |
| TCMT2 | MAPT | Microtubule-associated protein tau | Unclassified | P10636 |
| TCMT206 | CYP2A6 | Cytochrome P450 2A6 | Oxidoreductase | P11509 |
| TCMT207 | BACE1 | Beta-secretase 1 | Protease | P56817 |
| TCMT212 | SRC | Tyrosine-protein kinase SRC | Kinase | P12931 |
| TCMT223 | AKR1B1 | Aldose reductase | Oxidoreductase | P15121 |
| TCMT225 | CA13 | Carbonic anhydrase XIII | Lyase | Q8N1Q1 |
| TCMT248 | CXCL8 | Interleukin-8 | Unclassified | P10145 |
| TCMT260 | FLT3 | Tyrosine-protein kinase receptor FLT3 | Kinase | P36888 |
| TCMT265 | GSK3B | Glycogen synthase kinase-3 beta | Kinase | P49841 |
| TCMT3 | ALOX15 | Arachidonate 15-lipoxygenase | Oxidoreductase | P16050 |
| TCMT31 | CYP2C19 | Cytochrome P450 2C19 | Oxidoreductase | P33261 |
| TCMT33 | CYP3A4 | Cytochrome P450 3A4 | Oxidoreductase | P08684 |
| TCMT354 | AURKA | Serine/threonine-protein kinase Aurora-A | Kinase | O14965 |
| TCMT369 | IGF1R | Insulin-like growth factor I receptor | Kinase | P08069 |
| TCMT370 | KDR | Vascular endothelial growth factor receptor 2 | Kinase | P35968 |
| TCMT374 | AURKB | Serine/threonine-protein kinase Aurora-B | Kinase | Q96GD4 |
| TCMT377 | INSR | Insulin receptor | Kinase | P06213 |
| TCMT401 | MET | Hepatocyte growth factor receptor | Kinase | P08581 |
| TCMT418 | EPHB4 | Ephrin type-B receptor 4 | Kinase | P54760 |
| TCMT42 | KMT2A | Histone-lysine N-methyltransferase MLL | Transferase | Q03164 |
| TCMT423 | EGFR | Epidermal growth factor receptor erbB1 | Kinase | P00533 |
| TCMT436 | NUAK1 | NUAK family SNF1-like kinase 1 | Kinase | O60285 |
| TCMT441 | PTK2 | Focal adhesion kinase 1 | Kinase | Q05397 |
| TCMT457 | FLT4 | Vascular endothelial growth factor receptor 3 | Kinase | P35916 |
| TCMT479 | AKT1 | Serine/threonine-protein kinase AKT | Kinase | P31749 |
| TCMT484 | PLK1 | Serine/threonine-protein kinase PLK1 | Kinase | P53350 |
| TCMT502 | TEK | Tyrosine-protein kinase TIE-2 | Kinase | Q02763 |
| TCMT536 | PDGFRB | Platelet-derived growth factor receptor beta | Kinase | P09619 |
| TCMT61 | MCL1 | Induced myeloid leukemia cell differentiation protein Mcl-1 | Unclassified | Q07820 |
| TCMT620 | HSPA8 | Heat shock cognate 71 kDa protein | Unclassified | P11142 |
| TCMT626 | BRAF | Serine/threonine-protein kinase B-raf | Kinase | P15056 |
| TCMT69 | THRB | Thyroid hormone receptor beta-1 | Nuclear receptor | P10828 |
| TCMT704 | ERBB2 | Receptor protein-tyrosine kinase erbB-2 | Kinase | P04626 |
| TCMT721 | HSPA1A | Heat shock 70 kDa protein 1 | Unclassified | P0DMV8 |
| TCMT739 | GPR35 | G-protein coupled receptor 35 | GPCR | Q9HC97 |
| TCMT751 | DYRK1A | Dual-specificity tyrosine-phosphorylation regulated kinase 1A | Kinase | Q13627 |
| TCMT752 | CSNK2A1 | Casein kinase II alpha | Kinase | P68400 |
| TCMT753 | SMAD3 | Mothers against decapentaplegic homolog 3 | Unclassified | P84022 |
| TCMT754 | GSTP1 | Glutathione S-transferase Pi | Transferase | P09211 |
| TCMT755 | PLK4 | Serine/threonine-protein kinase PLK4 | Kinase | O00444 |
| TCMT756 | MAP3K8 | Mitogen-activated protein kinase kinase kinase 8 | Kinase | P41279 |
| TCMT757 | CARM1 | Histone-arginine methyltransferase CARM1 | Transferase | Q86X55 |
| TCMT8 | KDM4E | Lysine-specific demethylase 4D-like | Oxidoreductase | B2RXH2 |
| TCMT80 | MAPK1 | MAP kinase ERK2 | Kinase | P28482 |
| TCMT82 | ESR1 | Estrogen receptor alpha | Nuclear receptor | P03372 |
| TCMT87 | CYP2C9 | Cytochrome P450 2C9 | Oxidoreductase | P11712 |
Targeted Pathogenic Microbes by the Ingredient of Component
| Target ID | Target Name |
|---|---|
| TCMT1090 | Human immunodeficiency virus type 1 integrase |
| TCMT1108 | Integrase |
| TCMT1109 | Reverse transcriptase |
| TCMT1178 | Actinomyces viscosus |
| TCMT1190 | Plasmodium falciparum (isolate FcB1 / Columbia) |
| TCMT1218 | Staphylococcus aureus |
| TCMT1246 | Escherichia coli |
| TCMT1251 | Candida albicans |
| TCMT1253 | Penicillium chrysogenum |
| TCMT1382 | Plasmodium falciparum (isolate K1 / Thailand) |
| TCMT1412 | Salmonella typhimurium |
| TCMT1438 | Plasmodium falciparum |
| TCMT1454 | Bacillus subtilis |
| TCMT1458 | Filobasidiella neoformans |
| TCMT1462 | Streptococcus mutans |
| TCMT1463 | Mycobacterium tuberculosis |
Ingredient Structrues
Ingredient ID: TCMC761
Formula: C7H6O
Ingredient ID: TCMC2822
Formula: C15H24
Ingredient ID: TCMC1159
Formula: C10H12O2
Ingredient ID: TCMC1102
Formula: C14H6O8
Properties
| Ingredient ID | Formulae | Name | MW | AlogP | MlogP | XlogP | # HBA | # HBD | PSA | # Rotatable Bond | # Ring | # Heacy Atom | Lipinski RO5 Violation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TCMC761 | C7H6O | Benzaldehyde | 106.04 | -0.1924 | 2.12 | 3.08 | 1 | 0 | 17.07 | 1 | 1 | 8 | 0 |
| TCMC1102 | C14H6O8 | Ellagic Acid | 302.01 | -2.0234 | 2.12 | -0.046 | 2 | 4 | 133.52 | 4 | 4 | 22 | 0 |
| TCMC1159 | C10H12O2 | Eugenol | 164.08 | 0.5166 | 2.34 | 2.484 | 0 | 1 | 29.46 | 5 | 1 | 12 | 0 |
| TCMC2822 | C15H24 | Alpha-Humulone | 204.19 | 4.1708 | 3.11 | 5.94 | 0 | 0 | 0 | 4 | 1 | 15 | 1 |
Download Data
All data can be downloaded by:→ Selecting data type in the below download table
→ Then click the download button.
