Component: Pericarpium zanthoxyli 蜀椒


Description of the Component

Component ID
TCMH1970
Latin Name
Pericarpium zanthoxyli
English Name
Pricklyash peel
Chinese Pinyin Name
Shu Jiao
中文名
蜀椒
TCM Properties
Hot,Pungent
TCM Meridians
Spleen,Stomach,Kidney
Therapeutic Class English
For warming interior
Therapeutic Class Chinese
温里
Functions
warm the spleen and the stomach and relieve pain, kill worms, and relieve itching
Toxicity
NA
Geo-authentic habitats (道地产区)
NA
Reference
CFDA
Barcode ID
Barcode Source

TCM Prescriptions with the Component

Prescription ID Prescription English Name Prescription Chinese Name
TCMFx2812 Da Jian Zhong Decoction 大建中汤
TCMFx7376 Da Jian Zhong Decoction 大建中汤
TCMFx1647 Major Central Supporting Decoction 大建中汤
TCMFx2656 Major Construct the Middle Decoction 大建中汤

Targeted Human Proteins by the Ingredient of Component

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT162 UGT1A1 UDP-glucuronosyltransferase 1-1 Transferase P22309
TCMT187 AR Androgen Receptor Nuclear receptor P10275
TCMT248 CXCL8 Interleukin-8 Unclassified P10145
TCMT3 ALOX15 Arachidonate 15-lipoxygenase Oxidoreductase P16050
TCMT327 TRPV1 Vanilloid receptor Ion channel Q8NER1
TCMT33 CYP3A4 Cytochrome P450 3A4 Oxidoreductase P08684
TCMT81 ALOX12 Arachidonate 12-lipoxygenase Oxidoreductase P18054


Targeted Pathogenic Microbes by the Ingredient of Component

Target ID Target Name
TCMT1218 Staphylococcus aureus
TCMT1245 Phytophthora cactorum
TCMT1246 Escherichia coli
TCMT1251 Candida albicans
TCMT1253 Penicillium chrysogenum
TCMT1408 Colletotrichum gloeosporioides
TCMT1454 Bacillus subtilis
TCMT1455 Mycobacterium tuberculosis H37Rv
TCMT1462 Streptococcus mutans

Ingredient Structrues

Ingredient ID: TCMC2541
Formula: C10H18O

Ingredient ID: TCMC1737
Formula: C10H18O

Ingredient ID: TCMC1608
Formula: C10H16

Ingredient ID: TCMC1578
Formula: C11H14O2

Ingredient ID: TCMC1493
Formula: C10H18O

Ingredient ID: TCMC1159
Formula: C10H12O2

Ingredient ID: TCMC1134
Formula: C10H12O

Properties

Ingredient ID Formulae Name MW AlogP MlogP XlogP # HBA # HBD PSA # Rotatable Bond # Ring # Heacy Atom Lipinski RO5 Violation
TCMC1134 C10H12O Estragole 148.09 0.9769 2.45 3.658 0 0 9.23 4 1 11 0
TCMC1159 C10H12O2 Eugenol 164.08 0.5166 2.34 2.484 0 1 29.46 5 1 12 0
TCMC1493 C10H18O Linalool (+) 154.14 2.4692 2.45 2.468 1 1 20.23 8 0 11 0
TCMC1578 C11H14O2 Methyleugenol 178.1 0.9251 2.45 3.003 0 0 18.46 6 1 13 0
TCMC1608 C10H16 Myrcene 136.13 3.0936 2.56 4.17 0 0 0 6 0 10 0
TCMC1737 C10H18O Nerol 154.14 2.3397 2.45 2.524 1 1 20.23 8 0 11 0
TCMC2541 C10H18O Alpha-Terpineol 154.14 1.1223 2.45 2.369 1 1 20.23 5 1 11 0

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1. General Information of the Component  
2. TCM Prescriptions with the Component  
3. Putative Targets  
4. Activity & References for Filtering Putative Targets  
5. Ingredient Data & Chemical Structure Information (Properties, InChI, InChIkey, SMILES, etc.)